Pub Date : 2020-12-22DOI: 10.17677/fn20714807.2020.06.02
A. Rakhimov
{"title":"Quantum-chemical calculation of antiviral dexamethasone medication by mndo, ab initio and dft methods","authors":"A. Rakhimov","doi":"10.17677/fn20714807.2020.06.02","DOIUrl":"https://doi.org/10.17677/fn20714807.2020.06.02","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90155224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-27DOI: 10.17677/fn20714807.2019.06.02
L. Kiss
Functionalized β-lactams and their derivatives have generated increasing interest in medicinal chemistry over the last decades. Because of their pharmacological potential the chemistry of fluorinated β-lactams and β-amino acids is considered to be an expanding research field. The stereocontrolled synthesis of various fluorine-containing acylic β-lactams has been accomplished from some readily available unsaturated bicyclic β-lactam isomers. The synthetic strategy was based on ring-opening metathesis of unsaturated bicyclic azetidinones followed by cross-metathesis with fluorine-containing olefins. The cross-metathesis transformations, performed under various conditions with the aim of studying chemodiscrimination of the olefin bonds, resulted in the corresponding functionalized β-lactam derivatives.
{"title":"Stereocontrolled synthesis of fluorine-containing functionalized β-lactam derivatives through cross-metathesis reactions","authors":"L. Kiss","doi":"10.17677/fn20714807.2019.06.02","DOIUrl":"https://doi.org/10.17677/fn20714807.2019.06.02","url":null,"abstract":"Functionalized β-lactams and their derivatives have generated increasing interest in medicinal chemistry over the last decades. Because of their pharmacological potential the chemistry of fluorinated β-lactams and β-amino acids is considered to be an expanding research field. The stereocontrolled synthesis of various fluorine-containing acylic β-lactams has been accomplished from some readily available unsaturated bicyclic β-lactam isomers. The synthetic strategy was based on ring-opening metathesis of unsaturated bicyclic azetidinones followed by cross-metathesis with fluorine-containing olefins. The cross-metathesis transformations, performed under various conditions with the aim of studying chemodiscrimination of the olefin bonds, resulted in the corresponding functionalized β-lactam derivatives.","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74888425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-30DOI: 10.17677/fn20714807.2019.05.04
A. Yarosh
{"title":"Increasing the optical transparency of amorphous copolymers of perfluorinated dioxoles and vinyl esters using xenon difluoride","authors":"A. Yarosh","doi":"10.17677/fn20714807.2019.05.04","DOIUrl":"https://doi.org/10.17677/fn20714807.2019.05.04","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78832015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-30DOI: 10.17677/fn20714807.2019.05.03
A. Tyutyunov
{"title":"Effect of eliminated radical mass and molecular weight of homologs of alkyl halides, α,ω–dihaloalkanes, and α,ω–dibromoperfluoroalkanes on their fragmentation upon electron impact ionization","authors":"A. Tyutyunov","doi":"10.17677/fn20714807.2019.05.03","DOIUrl":"https://doi.org/10.17677/fn20714807.2019.05.03","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90788366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-30DOI: 10.17677/fn20714807.2019.05.01
A. Rakhimov
{"title":"Quantum chemical calculation of some acetanilide molecules by the AM1 method","authors":"A. Rakhimov","doi":"10.17677/fn20714807.2019.05.01","DOIUrl":"https://doi.org/10.17677/fn20714807.2019.05.01","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74940938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-30DOI: 10.17677/fn20714807.2019.05.02
N. Vasiliev
{"title":"Fluorine-containing β-diketones in the process of origination of luminescent nanoscale dispersion","authors":"N. Vasiliev","doi":"10.17677/fn20714807.2019.05.02","DOIUrl":"https://doi.org/10.17677/fn20714807.2019.05.02","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89338316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.17677/FN20714807.2019.04.04
O. Zamyshlyayeva
{"title":"Linear-Dendritic Block Copolymers Based on N-Isopropyl Acrylamide and Tris-(Pentaftorphenyl)Hermane","authors":"O. Zamyshlyayeva","doi":"10.17677/FN20714807.2019.04.04","DOIUrl":"https://doi.org/10.17677/FN20714807.2019.04.04","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88387338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.17677/FN20714807.2019.04.02
V. Dyachenko
{"title":"Synthesis and Antitumor Activity of 1-(1,1,1,3,3,3-Hexafluoro-2-Ferrocenylpropan-2-Yl)-1h-Imidazole","authors":"V. Dyachenko","doi":"10.17677/FN20714807.2019.04.02","DOIUrl":"https://doi.org/10.17677/FN20714807.2019.04.02","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83609049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.17677/FN20714807.2019.04.03
A. Rakhimov
{"title":"Quantum-Chemical Study of the Protonation Mechanism of P-Fluorostyrol by the MNDO Method","authors":"A. Rakhimov","doi":"10.17677/FN20714807.2019.04.03","DOIUrl":"https://doi.org/10.17677/FN20714807.2019.04.03","url":null,"abstract":"","PeriodicalId":12217,"journal":{"name":"Fluorine Notes","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88006571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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