Pub Date : 2025-10-28eCollection Date: 2025-10-01DOI: 10.1177/24730114251386025
Albert T Anastasio, Nicholas R Kiritsis, Isabel R Shaffrey, Francois Lintz, Canon Cornelius, Nacime S Mansur, John Dankert, Conor O'Neill, Cesar de Cesar Netto
Background: Ankle arthrodesis (AA) is a common treatment for end-stage ankle arthritis, chronic instability, and degenerative deformity. Although minimally invasive arthroscopic techniques may reduce soft tissue disruption, postoperative pain, and related morbidity, open techniques may be beneficial for treatment of patients with aberrant anatomy, insufficient bone stock, or complex deformity. This study aimed to determine whether arthroscopic AA is associated with lower rates of adverse events, pseudarthrosis, and health care use compared with open AA techniques at short-term and long-term intervals.
Methods: We conducted a retrospective analysis using the TriNetX research network. Patients undergoing AA were identified using Current Procedural Terminology (CPT) codes for arthroscopic (CPT 29899, n = 879) and open (CPT 27870, n = 10 604) procedures. Two cohorts were defined and propensity score-matched on age, sex, race, body mass index, nicotine dependence, chronic kidney disease, and type 2 diabetes mellitus (n = 873 each). Outcomes were evaluated within 30 days, 90 days, and 2 years.
Results: The arthroscopic AA cohort experienced significantly lower rates of any adverse event, infection, and hospital admission within the 30-day and 90-day outcome windows. Arthroscopic AA was associated with fewer emergency department visits and wound dehiscence within 90 days of surgery. A diagnosed pseudarthrosis within 2 years was more common in the open arthrodesis cohort. Rates of short-term myocardial infarction, cerebral infarct, transfusion, pulmonary embolism, and hematoma did not differ.
Conclusion: Arthroscopic AA was associated with significantly lower rates of medical complications at the short-term intervals, in addition to lower rates of nonunion within 2 years. Although observational, propensity-matched data are consistent with fewer short-term medical complications and lower 2-year nonunion after arthroscopic AA, the results should be interpreted with caution because of the inability to assess the degree of coronal or sagittal plane deformity in the included cases.
Level of evidence: Level III, retrospective cohort study.
背景:踝关节融合术(AA)是终末期踝关节关节炎、慢性不稳定和退行性畸形的常用治疗方法。虽然微创关节镜技术可以减少软组织破裂、术后疼痛和相关的发病率,但开放技术可能有利于治疗解剖异常、骨库存不足或复杂畸形的患者。本研究旨在确定在短期和长期的时间间隔内,与开放式AA技术相比,关节镜下AA是否与较低的不良事件发生率、假关节发生率和医疗保健使用率相关。方法:采用TriNetX研究网络进行回顾性分析。采用关节镜手术(CPT 29899, n = 879)和开放手术(CPT 27870, n = 10604)的现行程序术语(CPT)代码对AA患者进行鉴定。定义了两个队列,并根据年龄、性别、种族、体重指数、尼古丁依赖、慢性肾脏疾病和2型糖尿病进行倾向评分匹配(n = 873)。结果分别在30天、90天和2年内进行评估。结果:关节镜AA组在30天和90天预后窗口内的任何不良事件、感染和住院率均显著降低。关节镜下AA与手术90天内急诊就诊和伤口裂开的减少有关。在开放性关节融合术队列中,2年内诊断出假关节更常见。短期心肌梗死、脑梗死、输血、肺栓塞和血肿的发生率没有差异。结论:关节镜下AA与短期内较低的医疗并发症发生率以及较低的2年内不愈合率相关。尽管观察性倾向匹配的数据与关节镜下AA术后较少的短期医疗并发症和较低的2年骨不连相一致,但由于无法评估纳入病例的冠状面或矢状面畸形程度,因此应谨慎解释结果。证据等级:III级,回顾性队列研究。
{"title":"Arthroscopic Ankle Arthrodesis vs Open Ankle Arthrodesis: A Propensity-Matched, Retrospective Database Analysis of Medical Complications and 2-Year Nonunion Rates.","authors":"Albert T Anastasio, Nicholas R Kiritsis, Isabel R Shaffrey, Francois Lintz, Canon Cornelius, Nacime S Mansur, John Dankert, Conor O'Neill, Cesar de Cesar Netto","doi":"10.1177/24730114251386025","DOIUrl":"10.1177/24730114251386025","url":null,"abstract":"<p><strong>Background: </strong>Ankle arthrodesis (AA) is a common treatment for end-stage ankle arthritis, chronic instability, and degenerative deformity. Although minimally invasive arthroscopic techniques may reduce soft tissue disruption, postoperative pain, and related morbidity, open techniques may be beneficial for treatment of patients with aberrant anatomy, insufficient bone stock, or complex deformity. This study aimed to determine whether arthroscopic AA is associated with lower rates of adverse events, pseudarthrosis, and health care use compared with open AA techniques at short-term and long-term intervals.</p><p><strong>Methods: </strong>We conducted a retrospective analysis using the TriNetX research network. Patients undergoing AA were identified using <i>Current Procedural Terminology</i> (<i>CPT</i>) codes for arthroscopic (<i>CPT</i> 29899, n = 879) and open (<i>CPT</i> 27870, n = 10 604) procedures. Two cohorts were defined and propensity score-matched on age, sex, race, body mass index, nicotine dependence, chronic kidney disease, and type 2 diabetes mellitus (n = 873 each). Outcomes were evaluated within 30 days, 90 days, and 2 years.</p><p><strong>Results: </strong>The arthroscopic AA cohort experienced significantly lower rates of any adverse event, infection, and hospital admission within the 30-day and 90-day outcome windows. Arthroscopic AA was associated with fewer emergency department visits and wound dehiscence within 90 days of surgery. A diagnosed pseudarthrosis within 2 years was more common in the open arthrodesis cohort. Rates of short-term myocardial infarction, cerebral infarct, transfusion, pulmonary embolism, and hematoma did not differ.</p><p><strong>Conclusion: </strong>Arthroscopic AA was associated with significantly lower rates of medical complications at the short-term intervals, in addition to lower rates of nonunion within 2 years. Although observational, propensity-matched data are consistent with fewer short-term medical complications and lower 2-year nonunion after arthroscopic AA, the results should be interpreted with caution because of the inability to assess the degree of coronal or sagittal plane deformity in the included cases.</p><p><strong>Level of evidence: </strong>Level III, retrospective cohort study.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 4","pages":"24730114251386025"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12576266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-28eCollection Date: 2025-10-01DOI: 10.1177/24730114251386359
James Johnson, Leah Buch, Shannon King, Mia Knauf, Joshua Kim, Christopher Gross, Daniel Scott, Samuel Adams, Kenneth Dupont, David Safranski
Background: Achieving interfragmentary compression and stability is critical for successful bone healing in fracture fixation and arthrodesis procedures. Modern orthopaedic plating systems incorporating variable-angle screw designs offer greater versatility; however, the impact of screw trajectory on interfragmentary compression and contact area has not been adequately explored. We questioned if the resultant forces applied by screw orientation would follow the basic principles of vector geometry.
Methods: Interfragmentary compression and contact area were quantified in foam bone surrogate osteotomy models using plates allowing maximum screw angulation of either 15 or 30 degrees, with screws inserted at various angles. Cadaveric second-tarsometatarsal (TMT) arthrodesis constructs were subsequently used to validate the mechanical findings from surrogate testing.
Results: Compression and contact area increased from 0 degrees to 15 degrees to 30 degrees in surrogate models (overall analysis of variance P < .001). Angling screws in the second bone fragment after securing the plate to the first fragment produced the largest compression gains. In cadaveric second-TMT constructs, 30-degree divergence increased compression (~15-fold; 49.4 ± 35.1 N vs 3.4 ± 3.8 N; P < .001) and contact area (~4-fold; 47.8 ± 28.9 mm² vs 12.8 ± 7.3 mm²; P < .001) compared with 0-degree divergence.
Conclusion: With plate fixation, screw divergence from the arthrodesis/fracture line improved interfragmentary compression and contact area, particularly when divergent screws were inserted into the second bone fragment after the plate was secured to the first fragment. As hypothesized, the findings followed basic vector geometry.
Clinical relevance: Surgeons can optimize plate fixation quality and enhance stability in midfoot arthrodesis (and other procedures) by strategically angling locking screws in the second bone fragment after securing the plate to the first fragment. These biomechanical insights offer practical guidance for achieving superior interfragmentary compression and potentially reducing the risk of nonunion in clinical practice.
{"title":"Screw Angulation and Insertion Sequence Increase Interfragmentary Compression When Using Plates for Midfoot Arthrodesis: Foam-Surrogate and Cadaveric Validation.","authors":"James Johnson, Leah Buch, Shannon King, Mia Knauf, Joshua Kim, Christopher Gross, Daniel Scott, Samuel Adams, Kenneth Dupont, David Safranski","doi":"10.1177/24730114251386359","DOIUrl":"10.1177/24730114251386359","url":null,"abstract":"<p><strong>Background: </strong>Achieving interfragmentary compression and stability is critical for successful bone healing in fracture fixation and arthrodesis procedures. Modern orthopaedic plating systems incorporating variable-angle screw designs offer greater versatility; however, the impact of screw trajectory on interfragmentary compression and contact area has not been adequately explored. We questioned if the resultant forces applied by screw orientation would follow the basic principles of vector geometry.</p><p><strong>Methods: </strong>Interfragmentary compression and contact area were quantified in foam bone surrogate osteotomy models using plates allowing maximum screw angulation of either 15 or 30 degrees, with screws inserted at various angles. Cadaveric second-tarsometatarsal (TMT) arthrodesis constructs were subsequently used to validate the mechanical findings from surrogate testing.</p><p><strong>Results: </strong>Compression and contact area increased from 0 degrees to 15 degrees to 30 degrees in surrogate models (overall analysis of variance <i>P</i> < .001). Angling screws in the second bone fragment after securing the plate to the first fragment produced the largest compression gains. In cadaveric second-TMT constructs, 30-degree divergence increased compression (~15-fold; 49.4 ± 35.1 N vs 3.4 ± 3.8 N; <i>P</i> < .001) and contact area (~4-fold; 47.8 ± 28.9 mm<sup>²</sup> vs 12.8 ± 7.3 mm<sup>²</sup>; <i>P</i> < .001) compared with 0-degree divergence.</p><p><strong>Conclusion: </strong>With plate fixation, screw divergence from the arthrodesis/fracture line improved interfragmentary compression and contact area, particularly when divergent screws were inserted into the second bone fragment after the plate was secured to the first fragment. As hypothesized, the findings followed basic vector geometry.</p><p><strong>Clinical relevance: </strong>Surgeons can optimize plate fixation quality and enhance stability in midfoot arthrodesis (and other procedures) by strategically angling locking screws in the second bone fragment after securing the plate to the first fragment. These biomechanical insights offer practical guidance for achieving superior interfragmentary compression and potentially reducing the risk of nonunion in clinical practice.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 4","pages":"24730114251386359"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12576148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-28eCollection Date: 2025-10-01DOI: 10.1177/24730114251386022
Andrew P Thome, Jonathon D Backus, Hyo-Jung Jeong, Jeremy J McCormick, Jeffrey E Johnson
Background: Modified oblique Keller capsular interposition arthroplasty (MOKCIA) is a treatment for hallux rigidus that has been shown to have similar long-term outcomes compared with metatarsophalangeal (MTP) arthrodesis. The purpose of this study was to evaluate differences in the level of sport and other activity following MOKCIA or first MTP arthrodesis.
Methods: From 2005 to 2020, 58 MOKCIA and 112 arthrodesis patients were identified. Patients completed a sports-specific questionnaire (SSQ) along with the visual analog scale (VAS) pain/satisfaction, Foot and Ankle Ability Measure (FAAM), and Patient-Reported Outcomes Measurement Information System (PROMIS) instruments, which yielded 14 MOKCIA and 15 arthrodesis subjects.
Results: At an average 13 years' follow-up, the MOKCIA group participated in a mean of 3.4 ± 1.7 sport activities preoperatively and 3.4 ± 1.9 postoperatively, whereas arthrodesis patients participated in 3.5 ± 1.7 activities preoperatively and 2.9 ± 1.4 postoperatively (P = .22). Compared with preoperative, the MOKCIA group rated sporting activities as less difficult (10/12) and same difficulty (2/12). Hundred percent of patients in the MOKCIA group were satisfied with their overall level of activity following surgery, whereas 87% patients (13/15) in the arthrodesis group were satisfied. Patients in the MOKCIA group were able to participate in similar numbers of activities postoperatively, but arthrodesis patients had decreased activities. PROMIS, VAS pain/satisfaction, and FAAM Sports scores were similar between the groups.
Conclusion: We found that MOKCIA compared similarly with MTP arthrodesis in sports physical function at long-term follow-up. These results must be interpreted in light of the very low follow-up and retrospective recall of preoperative activities.
Level of evidence: Level III, retrospective cohort study.
{"title":"Long-term Return to Sports After Modified Oblique Keller Capsular Interposition Arthroplasty vs Arthrodesis for Advanced Hallux Rigidus: A Retrospective Cohort.","authors":"Andrew P Thome, Jonathon D Backus, Hyo-Jung Jeong, Jeremy J McCormick, Jeffrey E Johnson","doi":"10.1177/24730114251386022","DOIUrl":"10.1177/24730114251386022","url":null,"abstract":"<p><strong>Background: </strong>Modified oblique Keller capsular interposition arthroplasty (MOKCIA) is a treatment for hallux rigidus that has been shown to have similar long-term outcomes compared with metatarsophalangeal (MTP) arthrodesis. The purpose of this study was to evaluate differences in the level of sport and other activity following MOKCIA or first MTP arthrodesis.</p><p><strong>Methods: </strong>From 2005 to 2020, 58 MOKCIA and 112 arthrodesis patients were identified. Patients completed a sports-specific questionnaire (SSQ) along with the visual analog scale (VAS) pain/satisfaction, Foot and Ankle Ability Measure (FAAM), and Patient-Reported Outcomes Measurement Information System (PROMIS) instruments, which yielded 14 MOKCIA and 15 arthrodesis subjects.</p><p><strong>Results: </strong>At an average 13 years' follow-up, the MOKCIA group participated in a mean of 3.4 ± 1.7 sport activities preoperatively and 3.4 ± 1.9 postoperatively, whereas arthrodesis patients participated in 3.5 ± 1.7 activities preoperatively and 2.9 ± 1.4 postoperatively (<i>P</i> = .22). Compared with preoperative, the MOKCIA group rated sporting activities as less difficult (10/12) and same difficulty (2/12). Hundred percent of patients in the MOKCIA group were satisfied with their overall level of activity following surgery, whereas 87% patients (13/15) in the arthrodesis group were satisfied. Patients in the MOKCIA group were able to participate in similar numbers of activities postoperatively, but arthrodesis patients had decreased activities. PROMIS, VAS pain/satisfaction, and FAAM Sports scores were similar between the groups.</p><p><strong>Conclusion: </strong>We found that MOKCIA compared similarly with MTP arthrodesis in sports physical function at long-term follow-up. These results must be interpreted in light of the very low follow-up and retrospective recall of preoperative activities.</p><p><strong>Level of evidence: </strong>Level III, retrospective cohort study.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 4","pages":"24730114251386022"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12576122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-28eCollection Date: 2025-10-01DOI: 10.1177/24730114251386357
Alexandra M Stein, Janice Havasy, Adam Bitterman, John E Herzenberg
Graphical Abstract.
图形抽象。
{"title":"The Méary Angle: A Historical Perspective and Contemporary Review.","authors":"Alexandra M Stein, Janice Havasy, Adam Bitterman, John E Herzenberg","doi":"10.1177/24730114251386357","DOIUrl":"10.1177/24730114251386357","url":null,"abstract":"<p><p>Graphical Abstract.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 4","pages":"24730114251386357"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12576238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-18eCollection Date: 2025-10-01DOI: 10.1177/24730114251375029
Baïdir Haloui, Frank Nobels, Wahid Rezaie
Background: Diabetic forefoot ulcers often result from increased pressure on bony prominences, neuropathy, and poor limb perfusion. The management of these ulcers, particularly when infected, is challenging and can often lead to minor or even major amputation. This study aims to evaluate the efficacy and safety of minimally invasive surgical offloading of recurrent diabetic ulcers of the fifth metatarsal by minimally invasive fifth metatarsal osteotomy and bunionette removal.
Methods: A retrospective case series study was conducted of patients who underwent surgical treatment for diabetic foot ulcers on the lateral or plantar side of the fifth metatarsal head between January 2020 and May 2025. Outcomes included time to healing of the primary ulcer and surgical wound, ulcer recurrence, postoperative complications, and reoperation rates. Clinical and radiologic parameters of the feet were assessed, and patient satisfaction Coughlin scores were collected.
Results: Ten feet from 9 patients who did not respond successfully to conservative offloading were included. The mean age of the patients was 69.5 years. Five feet were classified as Wagner grade 3 wounds, and 4 as Wagner grade 2 wounds. The ulcers healed completely in a mean time of 9.8 weeks postoperatively. Two patients required 6 weeks of antibiotic treatment because of preexisting osteomyelitis. One postoperative infection occurred. There were no corrective failures, and all patients returned to wearing orthopaedic shoes postoperatively. The overall patient satisfaction using the Coughlin satisfaction score was "good" to "excellent."
Conclusion: Minimally invasive fifth metatarsal osteotomy with bunionette removal appears safe and effective for treating refractory diabetic ulcers of the fifth metatarsal head, including cases with active infection. However, larger studies with functional outcomes are needed to establish definitive treatment guidelines.
{"title":"Minimally Invasive Fifth Metatarsal Osteotomy and Bunionette Removal for Recurrent Diabetic Foot Ulcers: A Case Series.","authors":"Baïdir Haloui, Frank Nobels, Wahid Rezaie","doi":"10.1177/24730114251375029","DOIUrl":"10.1177/24730114251375029","url":null,"abstract":"<p><strong>Background: </strong>Diabetic forefoot ulcers often result from increased pressure on bony prominences, neuropathy, and poor limb perfusion. The management of these ulcers, particularly when infected, is challenging and can often lead to minor or even major amputation. This study aims to evaluate the efficacy and safety of minimally invasive surgical offloading of recurrent diabetic ulcers of the fifth metatarsal by minimally invasive fifth metatarsal osteotomy and bunionette removal.</p><p><strong>Methods: </strong>A retrospective case series study was conducted of patients who underwent surgical treatment for diabetic foot ulcers on the lateral or plantar side of the fifth metatarsal head between January 2020 and May 2025. Outcomes included time to healing of the primary ulcer and surgical wound, ulcer recurrence, postoperative complications, and reoperation rates. Clinical and radiologic parameters of the feet were assessed, and patient satisfaction Coughlin scores were collected.</p><p><strong>Results: </strong>Ten feet from 9 patients who did not respond successfully to conservative offloading were included. The mean age of the patients was 69.5 years. Five feet were classified as Wagner grade 3 wounds, and 4 as Wagner grade 2 wounds. The ulcers healed completely in a mean time of 9.8 weeks postoperatively. Two patients required 6 weeks of antibiotic treatment because of preexisting osteomyelitis. One postoperative infection occurred. There were no corrective failures, and all patients returned to wearing orthopaedic shoes postoperatively. The overall patient satisfaction using the Coughlin satisfaction score was \"good\" to \"excellent.\"</p><p><strong>Conclusion: </strong>Minimally invasive fifth metatarsal osteotomy with bunionette removal appears safe and effective for treating refractory diabetic ulcers of the fifth metatarsal head, including cases with active infection. However, larger studies with functional outcomes are needed to establish definitive treatment guidelines.</p><p><strong>Level of evidence: </strong>Level IV, case series.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 4","pages":"24730114251375029"},"PeriodicalIF":0.0,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12547117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145376308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-30eCollection Date: 2025-07-01DOI: 10.1177/24730114251373087
Valerie Carbajal, Brent Kokubun, Peyton Keeling, Daniel Choi, Casey Pyle, Arash Aminian, David Lee, Thomas G Harris
Background: Ankle fracture incidence is increasing in the elderly. There is a growing trend toward early weightbearing. We investigated the effects of early weightbearing after ankle open reduction and internal fixation (ORIF) in the geriatric population.
Methods: A retrospective cohort study was performed of patients aged ≥65 years who underwent ankle ORIF at 3 neighboring community hospitals from 2015 to 2024. A total of 97 were included, with 52 undergoing syndesmotic fixation. Postoperatively, patients were 50% partial weightbearing for 2-3 weeks. Afterward, patients were permitted to bear as much weight as tolerable. Recorded outcomes included fracture union, radiographic maintenance of alignment, hardware failures, wound complications, hardware removals, and the need for repeat surgery.
Results: Weightbearing as tolerated was initiated at an average of 16.6 days. All patients achieved fracture union without hardware failure, catastrophic loss of reduction (>2 mm displacement), accelerated posttraumatic arthritis, or need for revision surgery. Fourteen patients (14.4%) experienced minor complications not requiring return to surgery: 3 had delayed wound healing managed with protected weightbearing, 4 had surgical site infections treated with oral antibiotics, and 7 underwent elective hardware removal for symptomatic hardware at an average of 8.6 months postoperatively.
Conclusion: This is the largest study to date reporting on the effects of early weightbearing in the geriatric ankle ORIF population. We report no major complications and a limited number of soft tissue-related complications. In a patient population with a known morbidity from prolonged immobility, and with advances in recent fracture fixation, we hope our data help build confidence in early postoperative weightbearing.
Level of evidence: Level IV, retrospective cohort study.
{"title":"Early Weightbearing Following Open Reduction and Internal Fixation of Unstable Ankle Fractures in a Geriatric Population: A Retrospective Cohort Study.","authors":"Valerie Carbajal, Brent Kokubun, Peyton Keeling, Daniel Choi, Casey Pyle, Arash Aminian, David Lee, Thomas G Harris","doi":"10.1177/24730114251373087","DOIUrl":"10.1177/24730114251373087","url":null,"abstract":"<p><strong>Background: </strong>Ankle fracture incidence is increasing in the elderly. There is a growing trend toward early weightbearing. We investigated the effects of early weightbearing after ankle open reduction and internal fixation (ORIF) in the geriatric population.</p><p><strong>Methods: </strong>A retrospective cohort study was performed of patients aged ≥65 years who underwent ankle ORIF at 3 neighboring community hospitals from 2015 to 2024. A total of 97 were included, with 52 undergoing syndesmotic fixation. Postoperatively, patients were 50% partial weightbearing for 2-3 weeks. Afterward, patients were permitted to bear as much weight as tolerable. Recorded outcomes included fracture union, radiographic maintenance of alignment, hardware failures, wound complications, hardware removals, and the need for repeat surgery.</p><p><strong>Results: </strong>Weightbearing as tolerated was initiated at an average of 16.6 days. All patients achieved fracture union without hardware failure, catastrophic loss of reduction (>2 mm displacement), accelerated posttraumatic arthritis, or need for revision surgery. Fourteen patients (14.4%) experienced minor complications not requiring return to surgery: 3 had delayed wound healing managed with protected weightbearing, 4 had surgical site infections treated with oral antibiotics, and 7 underwent elective hardware removal for symptomatic hardware at an average of 8.6 months postoperatively.</p><p><strong>Conclusion: </strong>This is the largest study to date reporting on the effects of early weightbearing in the geriatric ankle ORIF population. We report no major complications and a limited number of soft tissue-related complications. In a patient population with a known morbidity from prolonged immobility, and with advances in recent fracture fixation, we hope our data help build confidence in early postoperative weightbearing.</p><p><strong>Level of evidence: </strong>Level IV, retrospective cohort study.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 3","pages":"24730114251373087"},"PeriodicalIF":0.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-30eCollection Date: 2025-07-01DOI: 10.1177/24730114251375027
Abhiram Dawar, Gnaneswar Chundi, Zachary Fuller, David B Ahn, Avani A Chopra, Sheldon S Lin, Tuckerman Jones
Background: Trimalleolar ankle fractures pose a challenge for surgical management, especially in high-risk populations such as the elderly and patients with comorbidities. Surgeons traditionally employ open reduction internal fixation (ORIF) to manage these injuries; however, some recent studies advocate for tibiotalocalcaneal arthrodesis (TTCA) as an alternative that minimizes soft tissue disruption and facilitates earlier weightbearing. This study compares complication and readmission rates associated with ORIF and TTCA in managing trimalleolar fractures, providing insight on complication risks throughout this patient population.
Methods: A retrospective analysis was performed using the 2016-2021 Nationwide Readmissions Database. Adult patients (≥18 years) diagnosed with trimalleolar ankle fractures who underwent either ORIF or TTCA were identified. To balance the cohorts, propensity score matching based on key comorbidities (defined as diabetes, hypertension, chronic kidney disease, osteoporosis, obesity, morbid obesity, or heart failure), age, and sex was performed. Primary outcomes included 30- and 90-day readmissions and complication rates; secondary outcomes were specific complications, including infection, nonunion, and malunion, assessed only in patients with ≥90 days' follow-up.
Results: A total of 602 patients were analyzed after propensity score matching (307 ORIF, 295 TTCA). TTCA patients experienced significantly higher overall complication rates compared to ORIF patients (35% [95% CI: 30.67%-41.56%] vs 13% [95% CI: 9.15%-16.53%], P < .001). Specifically, TTCA was associated with increased nonunion (10% [95% CI: 8.37%-15.67%] vs 2% [95% CI: 1.11%-4.63%], P < .001) and malunion rates (13% [95% CI: 9.53%-17.19%] vs 1% [95% CI: 0.06%-1.82%], P < .001). TTCA patients also demonstrated higher 30-day readmission rates (25% [95% CI: 21.42%-31.40%] vs 13% [95% CI: 10%-17.62%], P < .001) and 90-day readmission rates (20% [95% CI: 15.83%-24.94%] vs 10% [95% CI: 7.21%-13.98%], P < .001). In multivariable analysis, TTCA remained independently associated with higher complication risk (adjusted odds ratio: 4.10, 95% CI: 2.29-7.33, P < .001). Complication rate differences persisted across both high- and low-risk patient subgroups.
Conclusion: In this national database analysis, ORIF was associated with significantly lower complication and readmission rates compared with TTCA for trimalleolar ankle fractures. Despite theoretical advantages of TTCA in high-risk populations, these findings suggest ORIF may be preferable for most patients, with TTCA reserved for carefully selected cases where conventional fixation is unlikely to succeed. Given the limitations of administrative data, prospective randomized trials with longer follow-up are needed to definitively establish optimal treatment algorithms for this challenging pat
背景:三踝踝关节骨折对手术治疗提出了挑战,特别是在高危人群中,如老年人和有合并症的患者。外科医生传统上采用切开复位内固定(ORIF)来治疗这些损伤;然而,最近的一些研究提倡将胫距跟骨关节融合术(TTCA)作为一种替代方法,以最大限度地减少软组织损伤并促进早期负重。本研究比较了ORIF和TTCA治疗三踝骨折的并发症和再入院率,为该患者群体的并发症风险提供了见解。方法:使用2016-2021年全国再入院数据库进行回顾性分析。诊断为三踝踝关节骨折的成年患者(≥18岁)接受ORIF或TTCA治疗。为了平衡队列,根据主要合并症(定义为糖尿病、高血压、慢性肾病、骨质疏松症、肥胖、病态肥胖或心力衰竭)、年龄和性别进行倾向评分匹配。主要结局包括30天和90天的再入院和并发症发生率;次要结局是特定并发症,包括感染、不愈合和不愈合,仅在随访≥90天的患者中评估。结果:602例患者进行倾向评分匹配(ORIF 307例,TTCA 295例)。与ORIF患者相比,TTCA患者的总并发症发生率明显更高(35% [95% CI: 30.67%-41.56%] vs 13% [95% CI: 9.15%-16.53%], P P P P P P P P P结论:在这项国家数据库分析中,与TTCA相比,ORIF患者三踝踝关节骨折的并发症和再入院率显著降低。尽管理论上TTCA在高危人群中有优势,但这些研究结果表明ORIF可能更适合大多数患者,而TTCA保留给那些传统固定不太可能成功的精心挑选的病例。鉴于管理数据的局限性,需要进行前瞻性随机试验,随访时间更长,以明确地为这一具有挑战性的患者群体建立最佳治疗算法。证据等级:III级,预后不良。
{"title":"Tibiotalocalcaneal Arthrodesis vs Open Reduction Internal Fixation for Trimalleolar Ankle Fractures in High-Risk Patients: A National Database Analysis.","authors":"Abhiram Dawar, Gnaneswar Chundi, Zachary Fuller, David B Ahn, Avani A Chopra, Sheldon S Lin, Tuckerman Jones","doi":"10.1177/24730114251375027","DOIUrl":"10.1177/24730114251375027","url":null,"abstract":"<p><strong>Background: </strong>Trimalleolar ankle fractures pose a challenge for surgical management, especially in high-risk populations such as the elderly and patients with comorbidities. Surgeons traditionally employ open reduction internal fixation (ORIF) to manage these injuries; however, some recent studies advocate for tibiotalocalcaneal arthrodesis (TTCA) as an alternative that minimizes soft tissue disruption and facilitates earlier weightbearing. This study compares complication and readmission rates associated with ORIF and TTCA in managing trimalleolar fractures, providing insight on complication risks throughout this patient population.</p><p><strong>Methods: </strong>A retrospective analysis was performed using the 2016-2021 Nationwide Readmissions Database. Adult patients (≥18 years) diagnosed with trimalleolar ankle fractures who underwent either ORIF or TTCA were identified. To balance the cohorts, propensity score matching based on key comorbidities (defined as diabetes, hypertension, chronic kidney disease, osteoporosis, obesity, morbid obesity, or heart failure), age, and sex was performed. Primary outcomes included 30- and 90-day readmissions and complication rates; secondary outcomes were specific complications, including infection, nonunion, and malunion, assessed only in patients with ≥90 days' follow-up.</p><p><strong>Results: </strong>A total of 602 patients were analyzed after propensity score matching (307 ORIF, 295 TTCA). TTCA patients experienced significantly higher overall complication rates compared to ORIF patients (35% [95% CI: 30.67%-41.56%] vs 13% [95% CI: 9.15%-16.53%], <i>P</i> < .001). Specifically, TTCA was associated with increased nonunion (10% [95% CI: 8.37%-15.67%] vs 2% [95% CI: 1.11%-4.63%], <i>P</i> < .001) and malunion rates (13% [95% CI: 9.53%-17.19%] vs 1% [95% CI: 0.06%-1.82%], <i>P</i> < .001). TTCA patients also demonstrated higher 30-day readmission rates (25% [95% CI: 21.42%-31.40%] vs 13% [95% CI: 10%-17.62%], <i>P</i> < .001) and 90-day readmission rates (20% [95% CI: 15.83%-24.94%] vs 10% [95% CI: 7.21%-13.98%], <i>P</i> < .001). In multivariable analysis, TTCA remained independently associated with higher complication risk (adjusted odds ratio: 4.10, 95% CI: 2.29-7.33, <i>P</i> < .001). Complication rate differences persisted across both high- and low-risk patient subgroups.</p><p><strong>Conclusion: </strong>In this national database analysis, ORIF was associated with significantly lower complication and readmission rates compared with TTCA for trimalleolar ankle fractures. Despite theoretical advantages of TTCA in high-risk populations, these findings suggest ORIF may be preferable for most patients, with TTCA reserved for carefully selected cases where conventional fixation is unlikely to succeed. Given the limitations of administrative data, prospective randomized trials with longer follow-up are needed to definitively establish optimal treatment algorithms for this challenging pat","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 3","pages":"24730114251375027"},"PeriodicalIF":0.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-29eCollection Date: 2025-07-01DOI: 10.1177/24730114251372601
Alessandro Cattolico, Fabrizio Sergio, Alessia Boemio, Ottorino Catani, Massimo Noviello, Ciro Ivan De Girolamo, Luigi Bagella, Mario Boccino, Angela Lucariello, Luigi Aurelio Nasto, Enrico Pola, Fabio Zanchini
Background: Haglund syndrome is characterized by heel pain associated with posterosuperior calcaneal exostosis, insertional Achilles tendinopathy, and retrocalcaneal bursitis. When conservative treatments fail, surgical intervention is required. This study aims to evaluate the effectiveness of a combined surgical approach, integrating percutaneous resection of the calcaneal exostosis and proximal medial gastrocnemius release (PMGR) using the Barouk technique in treating Haglund syndrome. The goal is to assess whether this approach offers superior clinical outcomes compared to percutaneous resection alone.
Methods: We prospectively enrolled 224 patients undergoing combined percutaneous resection and PMGR, divided into group A (n = 106; with Achilles-plantar complex contracture) and group B (n = 118; without contracture) based on passive dorsiflexion testing. Outcomes were compared to 2 historical retrospective control groups treated with resection only: group 1 (n = 124; with contracture) and group 2 (n = 135; without contracture). All prospective patients received the combined treatment regardless of contracture status. Patients with body mass index >30 were excluded. The Foot Function Index (FFI) and Victorian Institute of Sport Assessment-Achilles (VISA-A) Questionnaire scores were collected at baseline and 3, 6, and 12 months.
Results: Groups A and B improved a mean 30 ± 5 FFI points and 40 ± 7 VISA-A points at 12 months (both P < .001). When compared to historical controls who underwent resection alone, the combined treatment groups showed statistically superior outcomes at all follow-up intervals (P < .05). However, these comparisons are limited by the nonconcurrent, unmatched study design.
Conclusion: This mixed prospective-retrospective study suggests potential benefits of adding Achilles-plantar complex lengthening to percutaneous calcaneal resection. However, the nonrandomized design, historical controls, and lack of patient/outcome assessor masking significantly limit causal inference. Although the combined approach showed statistically superior outcomes compared with historical controls, these findings should be considered hypothesis-generating pending validation in randomized controlled trials.
Level of evidence: Level III, retrospective-comparative cohort.
{"title":"Preliminary Anatomical and Surgical Assessment of Combined Percutaneous Resection and Proximal Medial Gastrocnemius Release vs Historical Controls in Treating Haglund syndrome: A Mixed Prospective-Retrospective Study.","authors":"Alessandro Cattolico, Fabrizio Sergio, Alessia Boemio, Ottorino Catani, Massimo Noviello, Ciro Ivan De Girolamo, Luigi Bagella, Mario Boccino, Angela Lucariello, Luigi Aurelio Nasto, Enrico Pola, Fabio Zanchini","doi":"10.1177/24730114251372601","DOIUrl":"10.1177/24730114251372601","url":null,"abstract":"<p><strong>Background: </strong>Haglund syndrome is characterized by heel pain associated with posterosuperior calcaneal exostosis, insertional Achilles tendinopathy, and retrocalcaneal bursitis. When conservative treatments fail, surgical intervention is required. This study aims to evaluate the effectiveness of a combined surgical approach, integrating percutaneous resection of the calcaneal exostosis and proximal medial gastrocnemius release (PMGR) using the Barouk technique in treating Haglund syndrome. The goal is to assess whether this approach offers superior clinical outcomes compared to percutaneous resection alone.</p><p><strong>Methods: </strong>We prospectively enrolled 224 patients undergoing combined percutaneous resection and PMGR, divided into group A (n = 106; with Achilles-plantar complex contracture) and group B (n = 118; without contracture) based on passive dorsiflexion testing. Outcomes were compared to 2 historical retrospective control groups treated with resection only: group 1 (n = 124; with contracture) and group 2 (n = 135; without contracture). All prospective patients received the combined treatment regardless of contracture status. Patients with body mass index >30 were excluded. The Foot Function Index (FFI) and Victorian Institute of Sport Assessment-Achilles (VISA-A) Questionnaire scores were collected at baseline and 3, 6, and 12 months.</p><p><strong>Results: </strong>Groups A and B improved a mean 30 ± 5 FFI points and 40 ± 7 VISA-A points at 12 months (both <i>P</i> < .001). When compared to historical controls who underwent resection alone, the combined treatment groups showed statistically superior outcomes at all follow-up intervals (<i>P</i> < .05). However, these comparisons are limited by the nonconcurrent, unmatched study design.</p><p><strong>Conclusion: </strong>This mixed prospective-retrospective study suggests potential benefits of adding Achilles-plantar complex lengthening to percutaneous calcaneal resection. However, the nonrandomized design, historical controls, and lack of patient/outcome assessor masking significantly limit causal inference. Although the combined approach showed statistically superior outcomes compared with historical controls, these findings should be considered hypothesis-generating pending validation in randomized controlled trials.</p><p><strong>Level of evidence: </strong>Level III, retrospective-comparative cohort.</p>","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 3","pages":"24730114251372601"},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12480791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-28eCollection Date: 2025-07-01DOI: 10.1177/24730114251373078
Rohan Bhimani, Marguerite A Mullen, Soheil Ashkani-Esfahani, Colin O'Neill, Gergory R Waryasz, Gino M M J Kerkhoffs, Christopher W DiGiovanni, Daniel Guss
<p><strong>Background: </strong>The clinical treatment of Weber B fibular fractures has primarily focused on the symmetry of the medial clear space. Numerous radiographic studies demonstrate no change in tibiotalar contact area until the deltoid ligament is disrupted. In contrast, more recent studies using weightbearing CT scan (WBCT) and 3D volume analysis suggest that medial clear space (MCS) volume can in fact increase in the setting of a Weber B fibular fracture even if initial radiographs are reassuring, possibly because of a loss of fibular buttress. This study aims to evaluate the ability of WBCT to quantify the impact of isolated Weber B fractures on MCS volume (3D), as well as understand the implication of increasing fibular displacement among patients with a symmetric MCS distance (1D) on initial radiographs.</p><p><strong>Methods: </strong>The study group included 18 patients with unilateral Weber B ankle fractures who underwent preoperative bilateral foot and ankle WBCT. The control group consisted of 60 patients with forefoot/midfoot conditions without ankle injury who underwent similar imaging. Measurements on WBCT images included (1) MCS distance; (2) syndesmotic area; (3) anterior, middle, and posterior distal tibiofibular distance; (4) fibular rotation; (5) distance from fibular tip to plafond; and (6) fibular fracture displacement. Additionally, volumetric measurements included (1) MCS volume, (2) syndesmotic joint volume from the tibial plafond extending to 3 cm and 5 cm proximally, and (3) lateral clear space volume were calculated. Area under the receiver operating characteristic (ROC) curve (AUC) analysis and Delong test were used, and optimal cutoff values to distinguish between stable and unstable Weber B fractures without syndesmotic instability and MCS widening were determined using Youden J statistic.</p><p><strong>Results: </strong>Among patients with unilateral Weber B ankle fractures, all WBCT measurements showed no side-to-side difference in any parameter, except MCS volume (<i>P</i> values < .001). When compared to the uninjured side, fibular displacement up to 2 mm and up to 4 mm was associated with MCS volume increases of 37.1% and 51.8%, respectively, compared with the contralateral uninjured side. Based on ROC analysis and Youden J statistic, a fibular fracture displacement of 2.3 mm was identified as the optimal threshold associated with a significant increase in MCS volume (AUC, 0.81; sensitivity, 77.8%; specificity, 80%). The control group showed no side-to-side difference in any of the measurements.</p><p><strong>Conclusion: </strong>In this preliminary study using WBCT, 3D MCS volume measurements showed statistical differences in Weber B fibular fractures compared with the contralateral side, even when 1D distance measurements appeared symmetric. A displacement threshold of 2.3 mm was identified through ROC analysis, although the clinical significance of these volumetric changes remains unclear and require
{"title":"Weightbearing CT Assessment of Medial Clear Space Volume Changes in Weber B Fractures: A Preliminary Analysis.","authors":"Rohan Bhimani, Marguerite A Mullen, Soheil Ashkani-Esfahani, Colin O'Neill, Gergory R Waryasz, Gino M M J Kerkhoffs, Christopher W DiGiovanni, Daniel Guss","doi":"10.1177/24730114251373078","DOIUrl":"10.1177/24730114251373078","url":null,"abstract":"<p><strong>Background: </strong>The clinical treatment of Weber B fibular fractures has primarily focused on the symmetry of the medial clear space. Numerous radiographic studies demonstrate no change in tibiotalar contact area until the deltoid ligament is disrupted. In contrast, more recent studies using weightbearing CT scan (WBCT) and 3D volume analysis suggest that medial clear space (MCS) volume can in fact increase in the setting of a Weber B fibular fracture even if initial radiographs are reassuring, possibly because of a loss of fibular buttress. This study aims to evaluate the ability of WBCT to quantify the impact of isolated Weber B fractures on MCS volume (3D), as well as understand the implication of increasing fibular displacement among patients with a symmetric MCS distance (1D) on initial radiographs.</p><p><strong>Methods: </strong>The study group included 18 patients with unilateral Weber B ankle fractures who underwent preoperative bilateral foot and ankle WBCT. The control group consisted of 60 patients with forefoot/midfoot conditions without ankle injury who underwent similar imaging. Measurements on WBCT images included (1) MCS distance; (2) syndesmotic area; (3) anterior, middle, and posterior distal tibiofibular distance; (4) fibular rotation; (5) distance from fibular tip to plafond; and (6) fibular fracture displacement. Additionally, volumetric measurements included (1) MCS volume, (2) syndesmotic joint volume from the tibial plafond extending to 3 cm and 5 cm proximally, and (3) lateral clear space volume were calculated. Area under the receiver operating characteristic (ROC) curve (AUC) analysis and Delong test were used, and optimal cutoff values to distinguish between stable and unstable Weber B fractures without syndesmotic instability and MCS widening were determined using Youden J statistic.</p><p><strong>Results: </strong>Among patients with unilateral Weber B ankle fractures, all WBCT measurements showed no side-to-side difference in any parameter, except MCS volume (<i>P</i> values < .001). When compared to the uninjured side, fibular displacement up to 2 mm and up to 4 mm was associated with MCS volume increases of 37.1% and 51.8%, respectively, compared with the contralateral uninjured side. Based on ROC analysis and Youden J statistic, a fibular fracture displacement of 2.3 mm was identified as the optimal threshold associated with a significant increase in MCS volume (AUC, 0.81; sensitivity, 77.8%; specificity, 80%). The control group showed no side-to-side difference in any of the measurements.</p><p><strong>Conclusion: </strong>In this preliminary study using WBCT, 3D MCS volume measurements showed statistical differences in Weber B fibular fractures compared with the contralateral side, even when 1D distance measurements appeared symmetric. A displacement threshold of 2.3 mm was identified through ROC analysis, although the clinical significance of these volumetric changes remains unclear and require","PeriodicalId":12429,"journal":{"name":"Foot & Ankle Orthopaedics","volume":"10 3","pages":"24730114251373078"},"PeriodicalIF":0.0,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}