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Viral hepatitis, hallmarks and molecular features 病毒性肝炎的特征和分子特征
Orlando Vargas-Sierra, Nathalia Beatriz Camara-Medina, Nicole Vincze-Galicia, Camila Uriarte-Figueroa, Javiera Pozo-Montalvo, Perla Yaceli Uc-Uc, D. Rebolledo-Solleiro
Hepatitis is a liver inflammation which has different etiologies, it can be caused pharmacologically or can be associated with fatty liver or alcohol consumption. However, viral infection as the most important cause. Recently, the World Health Organization (WHO) has published reports of outbreaks of hepatitis of unknown etiology in several countries in children less than 16 years. In this review we describe the general aspects of viral hepatitis, the molecular description of the hepatotropic viruses, laboratory findings, molecular diagnosis, prevention strategies. In addition, the main characteristics of some viruses that are not hepatotropic but have been previously reported to be related to some types of hepatitis are mentioned. Finally, a brief description of new cases of hepatitis of unknown origin is given and the adverse effects of SARS COV-2 vaccines are briefly discussed.
肝炎是一种肝脏炎症,有不同的病因,它可以由药物引起,也可以与脂肪肝或饮酒有关。然而,病毒感染是最重要的原因。最近,世界卫生组织(世卫组织)公布了一些国家16岁以下儿童爆发不明原因肝炎的报告。在这篇综述中,我们描述了病毒性肝炎的一般方面,嗜肝病毒的分子描述,实验室发现,分子诊断,预防策略。此外,还提到了一些病毒的主要特征,这些病毒不是嗜肝性的,但以前曾报道与某些类型的肝炎有关。最后,简要介绍了不明原因肝炎的新发病例,并简要讨论了SARS COV-2疫苗的不良反应。
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引用次数: 0
The role of dupilumab in diverse allergic pathologies dupilumab在多种过敏病理中的作用
Marquelle Zerecero-Morcksharpea, Catherin Lizeth Reyes Altamirano, Edna Elisa García Vences
Allergic responses represent a significant health problem due to the ineffectiveness of current treatments, as they attempt to decrease the immune response triggered but are unable to create immune memory that reduces the intensity of such response, so the intensity of the response will always be the same as the first time. An allergic response is characterized by the exacerbated and prolonged release of immunoglobulin E (IgE) that triggers innate immune responses due to the activation of T lymphocytes towards a Th2 phenotype, responsible for the release of interleukins 3 and 4 (IL-3 and IL-4), and the activation of B lymphocytes towards IgE-producing plasma cells. Currently, monoclonal antibodies (mAbs) are used as treatment for various allergic pathologies as they can be used to inhibit the signaling pathways of various interleukins, inactivating the differentiation of T lymphocytes, B lymphocytes, and the production of IgE. One of the most versatile mAbs in the treatment of various allergic responses is Dupilumab, which is designed to inhibit the signaling chain of IL-3 and IL-4, more specifically, it binds to the α receptor of IL-4 and the cytokine-induced receptor complex IL-13. Dupilumab inhibits IL-4 and IL-13 through receptor 1, stopping the release of IgE and proinflammatory cytokines. This treatment can be used to control the inflammatory response caused by allergens. On the other hand, the use of Dupilumab is not patented as the treatment of choice for allergic pathologies. Therefore, in this review, we compile the results of clinical studies of Dupilumab and other mAbs in atopic dermatitis (AD), eosinophilic esophagitis (EoE), chronic rhinosinusitis with nasal polyps (CRSwNP), and asthma, with the aim of determining which of the mAbs has provided better results.
由于目前的治疗无效,过敏反应是一个重大的健康问题,因为它们试图减少触发的免疫反应,但无法产生免疫记忆,从而降低这种反应的强度,因此反应的强度将始终与第一次相同。过敏反应的特点是免疫球蛋白E (IgE)的释放加剧和延长,由于T淋巴细胞对Th2表型的激活引发先天免疫反应,负责释放白细胞介素3和4 (IL-3和IL-4),以及B淋巴细胞对产生IgE的浆细胞的激活。目前,单克隆抗体(mab)被用于治疗各种过敏性疾病,因为它们可以抑制各种白细胞介素的信号通路,使T淋巴细胞、B淋巴细胞的分化失活,并产生IgE。Dupilumab是治疗各种过敏反应中最通用的单克隆抗体之一,它被设计用于抑制IL-3和IL-4的信号链,更具体地说,它结合IL-4的α受体和细胞因子诱导的受体复合物IL-13。Dupilumab通过受体1抑制IL-4和IL-13,阻止IgE和促炎细胞因子的释放。这种治疗方法可以用来控制由过敏原引起的炎症反应。另一方面,Dupilumab作为过敏性疾病的治疗选择并没有获得专利。因此,在本综述中,我们汇总了Dupilumab和其他单抗在特应性皮炎(AD)、嗜酸性食管炎(EoE)、慢性鼻窦炎合并鼻息肉(CRSwNP)和哮喘中的临床研究结果,目的是确定哪一种单抗提供了更好的效果。
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引用次数: 0
Comparison of efficacy between face-to-face and online consultation against overweight and obesity 面对面和在线咨询对抗超重和肥胖的效果比较
Jessica Rubí Molina Tellez, D. Incontri-Abraham, J. A. Almeyda-Farfán, Antonio Ibarra
Introduction: Overweight and obesity have progressively increased in recent years. Online consultation has become a useful tool for healthcare professionals and patients that cannot be assisted through face-to-face consultation. Objectives: Our study aimed to compare the efficacy between online and face-to-face consultation as a strategy in the management of overweight and obesity. Material and Methods: An experimental, cross-sectional study was carried out in 88 patients between 25-30 years old. Patients were classified into two groups of 44 individuals: online and face-to-face consultation.  Nutritional evaluations were conducted in each consultation, which comprised of anthropometric, dietetic, and physical assessments. The therapy consisted of individually designed menus made by a specialist and other recommendations based on the World Health Association (WHO) guidelines.  Results: Most patients in both groups achieved normal anthropometric measurements after the intervention (41/44 face-to-face group; 39/44 online group). Intragroup analysis (before and after intervention) of body mass index (BMI), weight, and fat percentage in both groups revealed a significant improvement after the intervention (p<0.0001). Intergroup analysis of BMI (p<0.4031), weight (p<0.2265), and fat percentage (p<0.3872) showed no significant difference. The analysis of efficacy revealed an efficacy of up to 95% in the online consultation group when compared to the face-to-face consultation one. Conclusions: No significant difference was found between online and face-to-face groups. The efficacy of online consultation was 95%. These results allow us to conclude that online and face-to-face consultation have a similar efficacy.
近年来,超重和肥胖逐渐增加。对于无法通过面对面咨询获得帮助的医疗保健专业人员和患者来说,在线咨询已成为一种有用的工具。目的:我们的研究旨在比较在线咨询和面对面咨询作为超重和肥胖管理策略的疗效。材料与方法:对88例年龄在25-30岁之间的患者进行了一项实验性横断面研究。患者被分为两组,每组44人:在线咨询和面对面咨询。在每次咨询中进行营养评估,包括人体测量、饮食和身体评估。该疗法包括由专家单独设计的菜单和根据世界卫生协会(世卫组织)准则提出的其他建议。结果:干预后,两组患者均达到正常的人体测量值(41/44面对面组;39/44在线组)。组内分析(干预前后)两组体重指数(BMI)、体重、脂肪率均有显著改善(p<0.0001)。BMI (p<0.4031)、体重(p<0.2265)、脂肪率(p<0.3872)组间分析差异无统计学意义。疗效分析显示,与面对面咨询组相比,在线咨询组的疗效高达95%。结论:在线组与面对面组之间无显著差异。在线咨询的有效率为95%。这些结果使我们得出结论,在线咨询和面对面咨询具有相似的功效。
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引用次数: 0
Effect of a gamified digital platform in increasing learning about the prevention of metabolic syndrome, obesity, and type 2 diabetes mellitus 游戏化数字平台在提高对预防代谢综合征、肥胖和2型糖尿病的了解方面的作用
D. Incontri-Abraham, Rocio Macin-Segovia, Elisa Kobashi, Maritza Parada, Daniela González, Alejandro Galván, A. P. Ibarra-García, Antonio Ibarra
Introduction: Gamified digital platforms allow non-health related individuals to learn about the prevention, management and treatment of obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM). Objective: The purpose of this study was to evaluate whether a new gamified digital platform increases learning about the prevention of metabolic syndrome, obesity, and T2DM. Methods: An exploratory, randomized, cause-effect study was carried out in 150 children between 10 and 12 years of age. Three exploratory, cause-effect experiments were designed to evaluate each one of the following pathologies: T2DM, obesity and metabolic syndrome. For each experiment, two study groups of 25 individuals each were formed. The experimental group was asked to use the digital platform that contained the information on the pathology under study in an animated storytelling and playful way. The control group received written information about each pathology. The assessment was carried out by applying a validated questionnaire including basic questions about the three diseases. This test was performed before and after the intervention. Results: We found a significant improvement (p<0.05) in the post-intervention knowledge acquired within the experimental group about metabolic syndrome, obesity, and T2DM when using the digital platform and compared to the control group. Children in the control group significantly improved their scores after the intervention compared to their baseline ones. Conclusion: Gamified digital platforms have the potential to be a novel primary prevention method for metabolic diseases. The present study allows us to conclude that any validated learning instrument increases knowledge about metabolic diseases. However, gamified digital platforms significantly increase learning compared to other types of methods (written information).
导论:游戏化的数字平台允许非健康相关的个人了解肥胖、代谢综合征和2型糖尿病(T2DM)的预防、管理和治疗。目的:本研究的目的是评估一个新的游戏化数字平台是否增加了对预防代谢综合征、肥胖和2型糖尿病的了解。方法:对150名10 - 12岁儿童进行了一项探索性、随机、因果研究。设计了三个探索性的因果实验来评估以下病理:T2DM、肥胖和代谢综合征。每个实验都分为两个研究组,每组25人。实验组被要求使用数字平台,该平台以动画叙事和有趣的方式包含所研究的病理信息。对照组接受每项病理的书面信息。采用一份有效的问卷进行评估,其中包括有关这三种疾病的基本问题。该测试分别在干预前后进行。结果:实验组使用数字平台获得的代谢综合征、肥胖、T2DM的干预后知识与对照组相比有显著提高(p<0.05)。干预后,对照组儿童的得分明显高于基线水平。结论:游戏化数字平台有可能成为代谢性疾病的一种新型一级预防方法。目前的研究使我们得出结论,任何经过验证的学习工具都可以增加对代谢疾病的了解。然而,与其他类型的方法(书面信息)相比,游戏化的数字平台显著提高了学习效果。
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引用次数: 0
AIDS-related disseminated Kaposi Sarcoma: a case report 艾滋病相关弥散性卡波西肉瘤1例报告
Samanta Ruiz, Juan José Díaz-Vintimilla, Maximiliano Trevilla-Viveros, Rogelio Zapata-Arenas, Tamara Monserrat Mejia-Alcantara
Kaposi sarcoma (KS) is the most common malignant tumor in HIV-infected individuals. Although its most common form consists of skin and mucosal lesions, it can also present itself in a disseminated way affecting the gastrointestinal tract, lungs and eye structures. We present the case of a 27-year-old male patient with HIV infection and disseminated Kaposi sarcoma. Disseminated KS is an uncommon form of the disease. Therefore, it is important to take this into account, particularly in HIV-infected individuals with characteristic cutaneous lesions.
卡波西肉瘤(KS)是hiv感染者中最常见的恶性肿瘤。虽然其最常见的形式是皮肤和粘膜病变,但它也可以以播散性的方式出现,影响胃肠道、肺和眼睛结构。我们提出的情况下,27岁的男性患者与艾滋病毒感染和播散卡波西肉瘤。弥散性KS是一种罕见的疾病。因此,考虑到这一点是很重要的,特别是在有特征性皮肤病变的艾滋病毒感染者中。
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引用次数: 0
Anatomical zone where more injuries occur in four different dance styles: Hip-Hop, Classical Ballet, Contemporary dance and Irish dancing: a systematic review Hip-Hop、古典芭蕾、现代舞和爱尔兰舞四种不同舞蹈风格中更易受伤的解剖区:一项系统回顾
Michelle Elena Stewart-Reyes, Ángela Hernández Suárez, Alejandra Romo-Araiza
Introduction: To this date there is no systematic study that reviews which anatomical zone has a higher incidence of injuries in four different dance styles: hip-hop, classical ballet, contemporary dance, and Irish dancing. Objective: Summarize and determine the incidence of injuries by anatomical zones in elite, pre-professional and professional dancers who practice one of the following dance styles: ballet, contemporary dance, hip-hop and Irish dancing. Methods: Articles were searched according to the following criteria: year of publication (between 2016 and 2022), observational and cohort studies published in English, full text available, and analysis of the incidence of injuries in the dance styles of hip-hop, classical ballet, contemporary dance, and Irish dancing. MESH terms and Boolean operators used for the search were “injury AND dancers AND incidence”. Data sources: Databases used were ProQuest, Pubmed, Google Scholar, Elsevier, Clinical Key and ScienceDirect. Results: A total of 511 records were identified, and only 19 were included for the analysis. The results of the reviewed literature revealed that the ankle was the anatomical zone with the highest incidence to suffer an injury (62.9%), overuse injuries had a higher incidence rate (63%), and the joint/ligament was the most common musculoskeletal type of injury (36.84%). Conclusion: Overall, the lower extremity had the highest injury incidence rate; even though the four different dance styles have different techniques and biomechanics, the most reported anatomical zone to suffer an injury was the ankle.
到目前为止,还没有系统的研究回顾了在四种不同的舞蹈风格(嘻哈、古典芭蕾、现代舞和爱尔兰舞)中哪个解剖区域的损伤发生率更高。目的:总结并确定芭蕾、现代舞、街舞和爱尔兰舞四种舞蹈风格的精英舞者、预科舞者和专业舞者的解剖区域损伤发生率。方法:根据以下标准检索文章:发表年份(2016年至2022年),英文发表的观察性和队列研究,全文可查,分析嘻哈、古典芭蕾、现代舞和爱尔兰舞等舞蹈风格的损伤发生率。用于搜索的MESH术语和布尔运算符为“伤害和舞者和发生率”。数据来源:使用的数据库包括ProQuest、Pubmed、Google Scholar、Elsevier、Clinical Key和ScienceDirect。结果:共识别511条记录,其中仅19条纳入分析。文献综述结果显示,踝关节是损伤发生率最高的解剖区域(62.9%),过度使用损伤发生率较高(63%),关节/韧带是最常见的肌肉骨骼损伤类型(36.84%)。结论:总体而言,下肢损伤发生率最高;尽管四种不同的舞蹈风格有不同的技术和生物力学,但据报道,最容易受伤的解剖区域是脚踝。
{"title":"Anatomical zone where more injuries occur in four different dance styles: Hip-Hop, Classical Ballet, Contemporary dance and Irish dancing: a systematic review","authors":"Michelle Elena Stewart-Reyes, Ángela Hernández Suárez, Alejandra Romo-Araiza","doi":"10.36105/psrua.2022v2n4.04","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n4.04","url":null,"abstract":"Introduction: To this date there is no systematic study that reviews which anatomical zone has a higher incidence of injuries in four different dance styles: hip-hop, classical ballet, contemporary dance, and Irish dancing. Objective: Summarize and determine the incidence of injuries by anatomical zones in elite, pre-professional and professional dancers who practice one of the following dance styles: ballet, contemporary dance, hip-hop and Irish dancing. Methods: Articles were searched according to the following criteria: year of publication (between 2016 and 2022), observational and cohort studies published in English, full text available, and analysis of the incidence of injuries in the dance styles of hip-hop, classical ballet, contemporary dance, and Irish dancing. MESH terms and Boolean operators used for the search were “injury AND dancers AND incidence”. Data sources: Databases used were ProQuest, Pubmed, Google Scholar, Elsevier, Clinical Key and ScienceDirect. Results: A total of 511 records were identified, and only 19 were included for the analysis. The results of the reviewed literature revealed that the ankle was the anatomical zone with the highest incidence to suffer an injury (62.9%), overuse injuries had a higher incidence rate (63%), and the joint/ligament was the most common musculoskeletal type of injury (36.84%). Conclusion: Overall, the lower extremity had the highest injury incidence rate; even though the four different dance styles have different techniques and biomechanics, the most reported anatomical zone to suffer an injury was the ankle.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122757264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Relationship between mood disorders and functional decline in older adults during the COVID-19 pandemic COVID-19大流行期间老年人情绪障碍与功能下降的关系
Pamela Alejandra Salcido de Pablo, Marquelle Zerecero-Morcksharpe, Nazly Salgado-Capistrán, Sofía Paci-Martínez, Samantha Cervantes-Valadez
Introduction: During the COVID-19 pandemic, isolation and reduction in mobility have increased the rate of depression and anxiety. This paper reviews the incidence of mood disorders and functional decline in older adults during this period. Methods: We used the Geriatric Depression Scale, the Goldberg anxiety Scale, the Lawton and Brody, and Katz scales to draw our conclusions. Results: A total of 237 patients were clinically evaluated, being 163 women and 74 men.  Of the 163 women in the study, 117 suffered from anxiety and 122 from depression. Also, 75 women out of the 163 included in the study, had COVID-19. Of the 74 men evaluated, 35 presented symptoms of anxiety and 27 of depression, the group age that presented the most anxiety were adults between 60 and 69 years old, and depression between 80 and 89 years old. Of these men, 22 had COVID-19. Conclusion: Confinement during the COVID-19 pandemic has increased depression and anxiety levels in older adults, which in turn has had significant impact on their mental health.
导语:在2019冠状病毒病大流行期间,隔离和行动不便增加了抑郁和焦虑的发生率。本文综述了这一时期老年人情绪障碍和功能下降的发生率。方法:采用老年抑郁量表、Goldberg焦虑量表、Lawton and Brody量表和Katz量表得出结论。结果:临床评估共237例患者,其中女性163例,男性74例。参与研究的163名女性中,117人患有焦虑症,122人患有抑郁症。此外,在参与研究的163名女性中,有75名患有COVID-19。在接受评估的74名男性中,35人表现出焦虑症状,27人表现出抑郁症状,最焦虑的年龄组是60至69岁的成年人,最抑郁的年龄组是80至89岁的成年人。在这些人中,22人患有COVID-19。结论:2019冠状病毒病大流行期间的禁闭增加了老年人的抑郁和焦虑水平,这反过来对他们的心理健康产生了重大影响。
{"title":"Relationship between mood disorders and functional decline in older adults during the COVID-19 pandemic","authors":"Pamela Alejandra Salcido de Pablo, Marquelle Zerecero-Morcksharpe, Nazly Salgado-Capistrán, Sofía Paci-Martínez, Samantha Cervantes-Valadez","doi":"10.36105/psrua.2022v2n4.02","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n4.02","url":null,"abstract":"Introduction: During the COVID-19 pandemic, isolation and reduction in mobility have increased the rate of depression and anxiety. This paper reviews the incidence of mood disorders and functional decline in older adults during this period. Methods: We used the Geriatric Depression Scale, the Goldberg anxiety Scale, the Lawton and Brody, and Katz scales to draw our conclusions. Results: A total of 237 patients were clinically evaluated, being 163 women and 74 men.  Of the 163 women in the study, 117 suffered from anxiety and 122 from depression. Also, 75 women out of the 163 included in the study, had COVID-19. Of the 74 men evaluated, 35 presented symptoms of anxiety and 27 of depression, the group age that presented the most anxiety were adults between 60 and 69 years old, and depression between 80 and 89 years old. Of these men, 22 had COVID-19. Conclusion: Confinement during the COVID-19 pandemic has increased depression and anxiety levels in older adults, which in turn has had significant impact on their mental health.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128370276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social networks and COVID-19 vaccination hesitancy in Mexican older adults 社交网络与墨西哥老年人COVID-19疫苗接种犹豫
J. M. Fernandez-Villa, Victoria Galnares-Carcoba, Juan S. Solis-Mata, Circe Flores-Ruiz, M. Pérez‐Zepeda
Introduction: The importance of social networks is growing, impacting everyday life. At this stage of global COVID-19 vaccination roll-out, hesitancy to get immunized is slowing this process; it is thought that this decision could be impacted by information shared on social networks. Objective: Determine whether the use of social networks is associated with the willingness to get the COVID-19 vaccine. Methods: This is a secondary analysis of the ENSANUT COVID-19 study, that measures the impact of the pandemic on the Mexican population. Only older adults, aged 65 years or older, were included in this work. Face to face interviews were performed to determine social network utilization, willingness to get vaccinated, and socio-demographic information on health and COVID-19. Bivariate analysis and logistic regression were performed. Results: From a total of 1,490 older adults, 59.3 % were women whose mean age was 73.5 (SD 6.8), and 53.3% (n = 795) were willing to get a COVID-19 vaccine when available. In an adjusted multivariate logistic regression model, WhatsApp was found to be a significant variable related to lower risk of vaccine hesitancy (OR 0.43, 95% CI, 0.2–0.85; p = 0.016). Other variables related to vaccine hesitancy were being a woman (OR 1.58, 95% CI, 2–1.23; p < 0.001) and COVID-19 literacy (OR 1.32, 95% CI, 1.01–1.74; p = 0.047). Conclusion: The use of social networks such as WhatsApp is a factor that can influence older adult vaccination against COVID-19. Social networks, among other variables, should be taken into account when analyzing factors that lead to vaccination hesitancy in older adults.
引言:社交网络的重要性正在增长,影响着人们的日常生活。在全球推广COVID-19疫苗接种的这个阶段,对接种疫苗的犹豫正在减缓这一进程;据认为,这一决定可能会受到社交网络上分享的信息的影响。目的:确定社交网络的使用是否与COVID-19疫苗接种意愿相关。方法:这是对ENSANUT COVID-19研究的二次分析,该研究测量了大流行对墨西哥人口的影响。只有年龄在65岁或以上的老年人被纳入这项研究。进行面对面访谈,以确定社交网络利用率、接种疫苗的意愿以及有关健康和COVID-19的社会人口信息。进行双变量分析和逻辑回归。结果:在总共1490名老年人中,59.3%是女性,平均年龄为73.5岁(SD为6.8),53.3% (n = 795)的人愿意接种COVID-19疫苗。在调整后的多因素logistic回归模型中,WhatsApp是与疫苗犹豫风险降低相关的显著变量(OR 0.43, 95% CI, 0.2-0.85;P = 0.016)。与疫苗犹豫相关的其他变量为女性(OR 1.58, 95% CI, 2-1.23;p < 0.001)和COVID-19识字率(OR 1.32, 95% CI, 1.01-1.74;P = 0.047)。结论:WhatsApp等社交网络的使用是影响老年人COVID-19疫苗接种的一个因素。在分析导致老年人疫苗接种犹豫的因素时,应考虑社会网络和其他变量。
{"title":"Social networks and COVID-19 vaccination hesitancy in Mexican older adults","authors":"J. M. Fernandez-Villa, Victoria Galnares-Carcoba, Juan S. Solis-Mata, Circe Flores-Ruiz, M. Pérez‐Zepeda","doi":"10.36105/psrua.2022v2n3.02","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n3.02","url":null,"abstract":"Introduction: The importance of social networks is growing, impacting everyday life. At this stage of global COVID-19 vaccination roll-out, hesitancy to get immunized is slowing this process; it is thought that this decision could be impacted by information shared on social networks. Objective: Determine whether the use of social networks is associated with the willingness to get the COVID-19 vaccine. Methods: This is a secondary analysis of the ENSANUT COVID-19 study, that measures the impact of the pandemic on the Mexican population. Only older adults, aged 65 years or older, were included in this work. Face to face interviews were performed to determine social network utilization, willingness to get vaccinated, and socio-demographic information on health and COVID-19. Bivariate analysis and logistic regression were performed. Results: From a total of 1,490 older adults, 59.3 % were women whose mean age was 73.5 (SD 6.8), and 53.3% (n = 795) were willing to get a COVID-19 vaccine when available. In an adjusted multivariate logistic regression model, WhatsApp was found to be a significant variable related to lower risk of vaccine hesitancy (OR 0.43, 95% CI, 0.2–0.85; p = 0.016). Other variables related to vaccine hesitancy were being a woman (OR 1.58, 95% CI, 2–1.23; p < 0.001) and COVID-19 literacy (OR 1.32, 95% CI, 1.01–1.74; p = 0.047). Conclusion: The use of social networks such as WhatsApp is a factor that can influence older adult vaccination against COVID-19. Social networks, among other variables, should be taken into account when analyzing factors that lead to vaccination hesitancy in older adults.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114118824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prediabetic patients evaluated with Quantose™ IR and their relationship with anthropometric measurements through bioelectrical impedance analysis 采用Quantose™IR评估糖尿病前期患者,并通过生物电阻抗分析评估其与人体测量的关系
Vanessa Mota-Sanhuaa, José Alberto Rojas Jiménez, Diana Martínez Castañeda, Alejandro Covarrubias-Cortés, Georgina Flores García, Sandra López Ríos, Adriana Reyes Camacho, J. A. Jácome-Mondragón, Blanca Velázquez Hernández
Introduction: New metabolomic biomarkers as Quantose™ IR and anthropometric measurements using bioelectrical impedance analysis (BIA) provide relevant information on patients with insulin resistance and prediabetes. QuantoseTM IR is a novel metabolomic test to assess insulin resistance for screening and monitoring. Establishing a correlation between these variables is useful in clinical practice and, to our knowledge, there are no published studies that explore the relationship between Quantose™ IR and anthropometric measurements using BIA in patients with prediabetes. Objective: To evaluate the correlation between Quantose™ IR and BIA anthropometric variables (fat mass, FM; fat mass index, FMI; and body mass index, BMI) in Mexican patients with prediabetes, overweight, and obesity. Materials and Methods: This is an observational, transversal analytic study in 135 patients of both genders between 20 and 65 years of age, BMI 25.0–34.9, with diagnosis of prediabetes. The Quantose™ IR test was performed as well as anthropometric measurements (FM, FMI, and BMI) using BIA taken with Inbody 230TM. Pearson’s correlations and independent sample t-tests were estimated with a significance level of p < 0.05. Results: 135 patients were studied; 77% were female, aged 46 years in average. The prevalence of insulin resistance by Quantose™ IR was 71.1%. A positive correlation was confirmed between Quantose™ IR and FM, FMI, and BMI (p < 0.05). Patients with altered Quantose™ IR had higher FM, FMI, and BMI (p < 0.05). Conclusion: The data here presented confirm the existence of a positive and statistically significant correlation between Quantose™ IR and anthropometric measurements using BIA. This information may be useful for diagnosis and treatment in prediabetic, overweight, and obese patients.
新的代谢组学生物标志物如Quantose™IR和使用生物电阻抗分析(BIA)的人体测量测量提供了胰岛素抵抗和前驱糖尿病患者的相关信息。QuantoseTM IR是一种新的代谢组学测试,用于评估胰岛素抵抗的筛查和监测。建立这些变量之间的相关性在临床实践中是有用的,据我们所知,尚无已发表的研究探讨Quantose™IR与糖尿病前期患者使用BIA进行人体测量之间的关系。目的:评价Quantose™IR与BIA人体测量变量(脂肪质量、FM;脂肪质量指数;和身体质量指数(BMI))在墨西哥患有前驱糖尿病、超重和肥胖的患者中。材料和方法:这是一项观察性的横向分析研究,纳入135例年龄在20 - 65岁之间,BMI为25.0-34.9,诊断为前驱糖尿病的男女患者。使用Inbody 230TM采集的BIA进行Quantose™IR测试和人体测量(FM、FMI和BMI)。Pearson相关和独立样本t检验均以p < 0.05的显著性水平进行估计。结果:135例患者纳入研究;77%为女性,平均年龄46岁。Quantose™IR的胰岛素抵抗患病率为71.1%。Quantose™IR与FM、FMI、BMI呈正相关(p < 0.05)。Quantose™IR改变的患者有更高的FM、FMI和BMI (p < 0.05)。结论:本文的数据证实了Quantose™IR与BIA人体测量值之间存在正相关且具有统计学意义。这些信息可能对糖尿病前期、超重和肥胖患者的诊断和治疗有用。
{"title":"Prediabetic patients evaluated with Quantose™ IR and their relationship with anthropometric measurements through bioelectrical impedance analysis","authors":"Vanessa Mota-Sanhuaa, José Alberto Rojas Jiménez, Diana Martínez Castañeda, Alejandro Covarrubias-Cortés, Georgina Flores García, Sandra López Ríos, Adriana Reyes Camacho, J. A. Jácome-Mondragón, Blanca Velázquez Hernández","doi":"10.36105/psrua.2022v2n3.01","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n3.01","url":null,"abstract":"Introduction: New metabolomic biomarkers as Quantose™ IR and anthropometric measurements using bioelectrical impedance analysis (BIA) provide relevant information on patients with insulin resistance and prediabetes. QuantoseTM IR is a novel metabolomic test to assess insulin resistance for screening and monitoring. Establishing a correlation between these variables is useful in clinical practice and, to our knowledge, there are no published studies that explore the relationship between Quantose™ IR and anthropometric measurements using BIA in patients with prediabetes. Objective: To evaluate the correlation between Quantose™ IR and BIA anthropometric variables (fat mass, FM; fat mass index, FMI; and body mass index, BMI) in Mexican patients with prediabetes, overweight, and obesity. Materials and Methods: This is an observational, transversal analytic study in 135 patients of both genders between 20 and 65 years of age, BMI 25.0–34.9, with diagnosis of prediabetes. The Quantose™ IR test was performed as well as anthropometric measurements (FM, FMI, and BMI) using BIA taken with Inbody 230TM. Pearson’s correlations and independent sample t-tests were estimated with a significance level of p < 0.05. Results: 135 patients were studied; 77% were female, aged 46 years in average. The prevalence of insulin resistance by Quantose™ IR was 71.1%. A positive correlation was confirmed between Quantose™ IR and FM, FMI, and BMI (p < 0.05). Patients with altered Quantose™ IR had higher FM, FMI, and BMI (p < 0.05). Conclusion: The data here presented confirm the existence of a positive and statistically significant correlation between Quantose™ IR and anthropometric measurements using BIA. This information may be useful for diagnosis and treatment in prediabetic, overweight, and obese patients.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131407430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of early or late nutritional intervention with psychological support on symptoms associated with Anorexia Nervosa: a comparative study 早期或晚期营养干预加心理支持对神经性厌食症相关症状的影响:一项比较研究
Andrea Flores-Gamboa, Rocío Ivonne De la Vega-Morales, Lorena Tovar Barrientos, J. G. Serrano-Robles, Nicole Matz-Zyman, A. Ibarra
Introduction: Anorexia nervosa (AN) is a disease with increasing incidence and prevalence, favored by biological, psychological, familial, and social factors. Management must be interdisciplinary, involving the intervention of nutritionists and psychologists. Additionally, it is important to evaluate the effect of an early or a late onset of the intervention. Objective: To determine if early nutrition-based intervention along with psychological support leads to a decrease in the symptoms associated with Anorexia Nervosa, when compared with late intervention. Methods: To evaluate the above parameters, an exploratory study was proposed with a design of non-randomized clinical trial and a non-probability purposive sampling of n = 17 women with AN between 12 and 25 years of age (x̄ = 16.8 ± 3.6). According to the moment of the nutritional intervention with psychological support, the 17 women were divided into two groups: Group 1 (n = 10) start the intervention in the first six months after the onset of the disease while Group 2 (n = 7) started 3 years after the disease. The nutritional and psychological carried out consisted of three phases: individualized nutritional assessment, design of the meal plan according to the metabolic needs of each patient and nutritional indications, and an individualized psychological intervention. Both interventions were carried out once a week for six months, for a total of 24 psychological and nutritional sessions. The physical variables of body mass index (BMI) and arm muscle area (AMA) were measured. To assess emotional changes, the body image dissatisfaction subscale of the Eating Disorder Inventory (EDI) was used. Results: Six months after follow-up, the results showed statistically significant changes in the BMI (p <,0.01), AMA (p <,0.01) and body image dissatisfaction (p <,0.01) after the intervention. It was found that the early-intervention group presented lower values in BMI and AMA as compared to the late-intervention patients while both groups showed a marked reduction in body image dissatisfaction values. The late-intervention group presented the sharpest reduction. There was no significant difference in the variables BMI and AMA in the intragroup comparisons. Conclusion: The early-onset nutritional intervention with psychological support decreased the physical and emotional symptoms associated with AN.
摘要神经性厌食症(Anorexia neurosa, AN)是一种发病率和患病率不断上升的疾病,受生物、心理、家族和社会等因素的影响。管理必须是跨学科的,包括营养学家和心理学家的介入。此外,评估早期或晚期干预的效果也很重要。目的:确定与晚期干预相比,早期营养干预和心理支持是否能减少神经性厌食症相关症状。方法:为评价上述参数,采用非随机临床试验设计和非概率目的抽样,对n = 17例12 ~ 25岁(x′= 16.8±3.6)的an女性进行探索性研究。根据营养干预和心理支持的时间,将17名妇女分为两组:1组(n = 10)在发病后6个月开始干预,2组(n = 7)在发病后3年开始干预。营养和心理治疗包括三个阶段:个体化营养评估、根据每位患者的代谢需要和营养指征设计膳食计划、个体化心理干预。这两种干预措施每周进行一次,持续六个月,总共进行24次心理和营养治疗。测量身体质量指数(BMI)和手臂肌肉面积(AMA)等生理指标。采用进食障碍量表(EDI)的身体形象不满意量表评估情绪变化。结果:随访6个月后,干预后BMI (p < 0.01)、AMA (p < 0.01)、身体形象不满意度(p < 0.01)变化均有统计学意义。研究发现,早期干预组的BMI和AMA值均低于晚期干预组,而两组的身体形象不满意值均显著降低。晚期干预组下降幅度最大。组内比较BMI和AMA变量无显著差异。结论:早发性营养干预配合心理支持可降低AN相关的身体和情绪症状。
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Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare
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