An enormous amount of data is generated and compiled in several databases every year. Along with this, comes a demand for the analysis and interpretation of the entirety of this biological information. Taking care of this task, bioinformatics promises breakthroughs in research and development in complex biomedical areas. In just a few years since its beginning, bioinformatics has led to great progress and demonstrated its potential. It has created an opportunity to solve arising medical and molecular issues faster and more efficiently, as compared to the traditional approach. The present review aims to present some of the main applications of bioinformatics in the field of biomedicine, such as comparative genomics, biomarker identification, computer-aided drug design, vaccine design, and personalized medicine. In addition, we also cover some of its steadily reduced limitations.
{"title":"Bioinformatics approaches for Biomedical Research","authors":"Kasandra Aguilar Cázarez, Ernesto Andrade Collantes, Marisol Verdugo Meza, Claudia María de-la-Rocha-Morales, Cruz Fernando López-Carrera, Paúl Alexis López-Durán","doi":"10.36105/psrua.2022v2n3.04","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n3.04","url":null,"abstract":"An enormous amount of data is generated and compiled in several databases every year. Along with this, comes a demand for the analysis and interpretation of the entirety of this biological information. Taking care of this task, bioinformatics promises breakthroughs in research and development in complex biomedical areas. In just a few years since its beginning, bioinformatics has led to great progress and demonstrated its potential. It has created an opportunity to solve arising medical and molecular issues faster and more efficiently, as compared to the traditional approach. The present review aims to present some of the main applications of bioinformatics in the field of biomedicine, such as comparative genomics, biomarker identification, computer-aided drug design, vaccine design, and personalized medicine. In addition, we also cover some of its steadily reduced limitations.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131866509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-03DOI: 10.36105/psrua.2022v2n3.05
Germán Rivera Monroy, Federica Riccio Cuomo, Dunia Michelle Bustos Campa, Jorge Luis López Marthen
Atypical myeloid leukemia is a myeloproliferative neoplasm in which patients have a dysplastic increase in blood cells of the myeloid lineage as a result of hypercellular bone marrow. Our patient presented a positive Ph karyotype and a negative ABL/BCR transcript. Moreover, her age does not correspond to the mean of diagnosis. Her first treatment was hydroxyurea 1 g/kg for 60 days, which was not positive for the evolution of the disease and thus the elective treatment was changed to imatinib 400 mg/ day. After two months, the treatment has produced a favorable response, which leads to think that the therapy with imatinib offers better clinical results than other conventional ones. This text presents the study carried out at the Manuel Ávila Camacho National Medical Center and compares it with the existing literature regarding diagnosis and treatment to assess similarities and highlight specific points that may help in future case management.
{"title":"Philadelphia-positive atypical chronic myeloid leukemia, BCR/ABL negative: a case report","authors":"Germán Rivera Monroy, Federica Riccio Cuomo, Dunia Michelle Bustos Campa, Jorge Luis López Marthen","doi":"10.36105/psrua.2022v2n3.05","DOIUrl":"https://doi.org/10.36105/psrua.2022v2n3.05","url":null,"abstract":"Atypical myeloid leukemia is a myeloproliferative neoplasm in which patients have a dysplastic increase in blood cells of the myeloid lineage as a result of hypercellular bone marrow. Our patient presented a positive Ph karyotype and a negative ABL/BCR transcript. Moreover, her age does not correspond to the mean of diagnosis. Her first treatment was hydroxyurea 1 g/kg for 60 days, which was not positive for the evolution of the disease and thus the elective treatment was changed to imatinib 400 mg/ day. After two months, the treatment has produced a favorable response, which leads to think that the therapy with imatinib offers better clinical results than other conventional ones. This text presents the study carried out at the Manuel Ávila Camacho National Medical Center and compares it with the existing literature regarding diagnosis and treatment to assess similarities and highlight specific points that may help in future case management.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128783038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Obesity is a multifactorial chronic disease that involves many internal and external factors, causing the death of at least 2.8 million people each year, according to the World Health Organization. Therefore, there is a need for nobler treatments to lose weight. Probiotic foods are classified as functional foods due to their nutritional contribution. Objective: To describe the impact of probiotic foods in the treatment of obesity. Methods: A review of 61 studies from different databases was carried out. Results: It is known that probiotics have several action mechanisms that beneficially affect the gut microbiota to maintain homoeostasis in the whole organism. The relationship between these microorganisms and the control and modulation of a person’s body weight has been observed. Conclusion: The beneficial effects of probiotics are strain-specific and may impact obesity through different action mechanisms, such as abdominal fat decrease, changes in inflammatory biomarkers, microbiota restoration, and reduction in triglycerides serum levels.
{"title":"Probiotic foods as functional foods for modulating obesity","authors":"Bárbara Gallegos-Inzunza, Jimena Prado-Ramírez, Alejandra Romo-Araiza","doi":"10.36105/PSRUA.2021V1N2.05","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N2.05","url":null,"abstract":"Introduction: Obesity is a multifactorial chronic disease that involves many internal and external factors, causing the death of at least 2.8 million people each year, according to the World Health Organization. Therefore, there is a need for nobler treatments to lose weight. Probiotic foods are classified as functional foods due to their nutritional contribution. Objective: To describe the impact of probiotic foods in the treatment of obesity. Methods: A review of 61 studies from different databases was carried out. Results: It is known that probiotics have several action mechanisms that beneficially affect the gut microbiota to maintain homoeostasis in the whole organism. The relationship between these microorganisms and the control and modulation of a person’s body weight has been observed. Conclusion: The beneficial effects of probiotics are strain-specific and may impact obesity through different action mechanisms, such as abdominal fat decrease, changes in inflammatory biomarkers, microbiota restoration, and reduction in triglycerides serum levels.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114997622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurodegenerative diseases are clinical manifestations that depend on the anatomy and function of the affected areas. Amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are some of these diseases, but they are also autoimmune and their etiology makes treatments limited and of little therapeutic efficacy. Currently, some clinical research advances can be pillars for the development of new treatments for these diseases. Therefore, the objective of this review is to describe the latest clinical advances in ALS and MS as well as their results in clinical recovery in randomized clinical trials, meta-analyzes, and full-text systematic reviews conducted in humans and rats, published in English and Spanish in the last 5 years, using PubMed, SciELO, and Cochrane. For clinical trials to be included, they had to provide a detailed breakdown of randomization methods, diagnostic criteria, intervention details, and efficacy evaluation. The results show that, so far, available medications, like riluzole and edaravone for ALS and fingolimod, dimethyl fumarate, and IFN β-1b for MS, only prolong the life of the patient. Among these drugs are also glutamate neurotransmitter antagonists, immunomodulators and even antioxidants; each of them showed significant improvement in the reviewed trials. Similarly, other non-pharmaceutical treatments, as the 600-mg dose of curcumin in the diet for ALS, showed improvement of the patients’ conditions. Regarding MS, more studies should be carried out on autotransplantation with adiposederived mesenchymal stem cells (AdMSCs) to investigate the potential therapeutic benefit of this technique in phases prior to secondary-progressive (SPMS).
{"title":"Clinical advances in multiple sclerosis and amyotrophic lateral sclerosis treatment: A review","authors":"Marquelle Zerecero-Morcksharpe, Elisa García-Vences","doi":"10.36105/PSRUA.2021V1N2.06","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N2.06","url":null,"abstract":"Neurodegenerative diseases are clinical manifestations that depend on the anatomy and function of the affected areas. Amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are some of these diseases, but they are also autoimmune and their etiology makes treatments limited and of little therapeutic efficacy. Currently, some clinical research advances can be pillars for the development of new treatments for these diseases. Therefore, the objective of this review is to describe the latest clinical advances in ALS and MS as well as their results in clinical recovery in randomized clinical trials, meta-analyzes, and full-text systematic reviews conducted in humans and rats, published in English and Spanish in the last 5 years, using PubMed, SciELO, and Cochrane. For clinical trials to be included, they had to provide a detailed breakdown of randomization methods, diagnostic criteria, intervention details, and efficacy evaluation. The results show that, so far, available medications, like riluzole and edaravone for ALS and fingolimod, dimethyl fumarate, and IFN β-1b for MS, only prolong the life of the patient. Among these drugs are also glutamate neurotransmitter antagonists, immunomodulators and even antioxidants; each of them showed significant improvement in the reviewed trials. Similarly, other non-pharmaceutical treatments, as the 600-mg dose of curcumin in the diet for ALS, showed improvement of the patients’ conditions. Regarding MS, more studies should be carried out on autotransplantation with adiposederived mesenchymal stem cells (AdMSCs) to investigate the potential therapeutic benefit of this technique in phases prior to secondary-progressive (SPMS).","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115615603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-06DOI: 10.36105/PSRUA.2021V1N2.01
J. F. Rivas-Vilchis, E. Barrera-Escorcia
Introduction: One of the striking complications of diabetes mellitus is arterial circulatory dysfunction. The 30:15 ratio is an orthostatic index commonly used to diagnose circulatory alterations in diabetic patients with a long evolution. Indices obtained from the second derivative of photoplethysmogram (SDPPG) or acceleration photoplethysmogram (APG) characterize arterial pathological changes. Aim: To compare the cardiovascular response of non-diabetic subjects to active standing versus that of type-2 diabetes (DM2) patients using APG indices. Methods: Digital photoplethysmography (PPG) was obtained from healthy subjects (n = 15, age ± SD, 44.6 ± 7.2 years) and DM2 patients (n = 15, age ± SD, 48.3 ± 7.9 years). The 30:15 ratio, b/a, d/a, and APG-AI, all APG-based, of the participants were calculated and compared at baseline, 15 and 30 s. Results: Comparison of the 30:15 ratios between groups did not show a significant difference. No significant differences were observed between the APG indices in the two groups in the baseline period. However, d/a decreased, and APG-AI increased significantly at beat 30 after active standing in non-diabetic subjects. Values of APG indices in DM2 patients did not show significant changes. Conclusion: The results suggest that APG indices could be used to detect early vascular dysfunctions in DM2 patients.
{"title":"Orthostatic response in patients with type 2 diabetes mellitus evaluated through acceleration photoplethysmogram","authors":"J. F. Rivas-Vilchis, E. Barrera-Escorcia","doi":"10.36105/PSRUA.2021V1N2.01","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N2.01","url":null,"abstract":"Introduction: One of the striking complications of diabetes mellitus is arterial circulatory dysfunction. The 30:15 ratio is an orthostatic index commonly used to diagnose circulatory alterations in diabetic patients with a long evolution. Indices obtained from the second derivative of photoplethysmogram (SDPPG) or acceleration photoplethysmogram (APG) characterize arterial pathological changes. Aim: To compare the cardiovascular response of non-diabetic subjects to active standing versus that of type-2 diabetes (DM2) patients using APG indices. Methods: Digital photoplethysmography (PPG) was obtained from healthy subjects (n = 15, age ± SD, 44.6 ± 7.2 years) and DM2 patients (n = 15, age ± SD, 48.3 ± 7.9 years). The 30:15 ratio, b/a, d/a, and APG-AI, all APG-based, of the participants were calculated and compared at baseline, 15 and 30 s. Results: Comparison of the 30:15 ratios between groups did not show a significant difference. No significant differences were observed between the APG indices in the two groups in the baseline period. However, d/a decreased, and APG-AI increased significantly at beat 30 after active standing in non-diabetic subjects. Values of APG indices in DM2 patients did not show significant changes. Conclusion: The results suggest that APG indices could be used to detect early vascular dysfunctions in DM2 patients.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129913921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-06DOI: 10.36105/PSRUA.2021V1N2.02
Karla Castillo-Gaspar, Valeria Román-Ayala, Adriana Domínguez-K Rescala, Karla Ramírez-Gualito
Polyurethane has been used and over-exploited worldwide in the manufacture of different goods, but it is hard to break down and represents an important contaminant due to its accumulation when discarded. Recent research findings have shown that several bacteria and their enzymes can biodegrade various plastics, such as polyurethane. In this review, we sought to group, analyze, and relate the techniques used by different bacterial species to biodegrade polyurethane that have been identified in different studies by searching databases, such as PubMed, Web of Science, and Scopus. Different species of proteobacteria, actinobacteria, and endobacteria biodegrade polyurethane by oxidation and hydrolysis to obtain carbon and nitrogen sources. Changes as weight loss, tensile strength, and chemical and surface changes were observed in polymer properties, showing that biological technologies have a direct impact on polyurethane by modifying the molecule in different ways.
聚氨酯已经在世界范围内被用于制造不同的商品，但它很难分解，并且由于其丢弃时的积累而成为一种重要的污染物。最近的研究结果表明，几种细菌及其酶可以生物降解各种塑料，如聚氨酯。在这篇综述中，我们试图通过检索PubMed、Web of Science和Scopus等数据库，对不同细菌种类用于生物降解聚氨酯的技术进行分组、分析和关联。不同种类的变形菌、放线菌和内细菌通过氧化和水解生物降解聚氨酯以获得碳和氮源。在聚合物性能中观察到失重、拉伸强度、化学和表面变化等变化，表明生物技术通过不同方式改变分子对聚氨酯产生直接影响。
{"title":"Effect of different bacteria on the biodegradation of polyurethane","authors":"Karla Castillo-Gaspar, Valeria Román-Ayala, Adriana Domínguez-K Rescala, Karla Ramírez-Gualito","doi":"10.36105/PSRUA.2021V1N2.02","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N2.02","url":null,"abstract":"Polyurethane has been used and over-exploited worldwide in the manufacture of different goods, but it is hard to break down and represents an important contaminant due to its accumulation when discarded. Recent research findings have shown that several bacteria and their enzymes can biodegrade various plastics, such as polyurethane. In this review, we sought to group, analyze, and relate the techniques used by different bacterial species to biodegrade polyurethane that have been identified in different studies by searching databases, such as PubMed, Web of Science, and Scopus. Different species of proteobacteria, actinobacteria, and endobacteria biodegrade polyurethane by oxidation and hydrolysis to obtain carbon and nitrogen sources. Changes as weight loss, tensile strength, and chemical and surface changes were observed in polymer properties, showing that biological technologies have a direct impact on polyurethane by modifying the molecule in different ways.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134502289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-06DOI: 10.36105/PSRUA.2021V1N2.04
Galit Wohlmuth-Cohen, Felix León-Avila
Introduction: To date, there is no systematic study focused on posture-related musculoskeletal pain in college students. Objective: Summarize the evidence of musculoskeletal pain in college students. Eligible criteria: Year of publication between 2015 and 2020, observational studies published in English, full text available, and analysis of the presence of musculoskeletal pain in college students. MESH terms and Boolean operators used for the search were pain AND musculoskeletal AND college students. Data sources: Databases used were PubMed, ClinicalKey, ProQuest, ResearchGate, and ScienceDirect. Results: A total of 318 records were identified out of which 296 were excluded, and only 22 were included for analysis. The majority of the records involved college students form the general population, while five involved dental students and five, health science students. The majority of the records involved a setting in which the student was in a constant sitting position, only two involved a dental setting, and one involved a laboratory setting. Conclusions: The most reported sites of pain were neck, shoulders, and upper and lower back.
{"title":"Musculoskeletal pain in college students: a systematic review","authors":"Galit Wohlmuth-Cohen, Felix León-Avila","doi":"10.36105/PSRUA.2021V1N2.04","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N2.04","url":null,"abstract":"Introduction: To date, there is no systematic study focused on posture-related musculoskeletal pain in college students. Objective: Summarize the evidence of musculoskeletal pain in college students. Eligible criteria: Year of publication between 2015 and 2020, observational studies published in English, full text available, and analysis of the presence of musculoskeletal pain in college students. MESH terms and Boolean operators used for the search were pain AND musculoskeletal AND college students. Data sources: Databases used were PubMed, ClinicalKey, ProQuest, ResearchGate, and ScienceDirect. Results: A total of 318 records were identified out of which 296 were excluded, and only 22 were included for analysis. The majority of the records involved college students form the general population, while five involved dental students and five, health science students. The majority of the records involved a setting in which the student was in a constant sitting position, only two involved a dental setting, and one involved a laboratory setting. Conclusions: The most reported sites of pain were neck, shoulders, and upper and lower back.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122495131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-22DOI: 10.36105/PSRUA.2021V1N1.08
Bethliza Alejandro Juárez, Patrick Fleischmann-de la Parra, Karla Tania Esmeralda Rayo-Mercado, T. Ponce-Lopez
Diabetes mellitus is a complex and chronic metabolic disorder characterized by hyperglycemia. Part of the treatment for this condition is the administration of insulin, a protein that directly influences blood glucose levels. It is traditionally administered parenterally; however, new alternative ways for its application seek greater efficiency and less invasiveness. The objective of this article is to compare the different methods of insulin administration, taking into account new technologies. This review article provides an overview of diabetes and insulin, highlights the advantages and disadvantages of insulin delivery methods (subcutaneous, inhaled, oral, and buccal), and shows the new technologies that include biotechnological applications.
{"title":"Comparison between insulin delivery methods: subcutaneous, inhaled, oral, and buccal","authors":"Bethliza Alejandro Juárez, Patrick Fleischmann-de la Parra, Karla Tania Esmeralda Rayo-Mercado, T. Ponce-Lopez","doi":"10.36105/PSRUA.2021V1N1.08","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N1.08","url":null,"abstract":"Diabetes mellitus is a complex and chronic metabolic disorder characterized by hyperglycemia. Part of the treatment for this condition is the administration of insulin, a protein that directly influences blood glucose levels. It is traditionally administered parenterally; however, new alternative ways for its application seek greater efficiency and less invasiveness. The objective of this article is to compare the different methods of insulin administration, taking into account new technologies. This review article provides an overview of diabetes and insulin, highlights the advantages and disadvantages of insulin delivery methods (subcutaneous, inhaled, oral, and buccal), and shows the new technologies that include biotechnological applications.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"07 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121780308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-22DOI: 10.36105/PSRUA.2021V1N1.01
E. Martínez-Solís, Abraham Atman Hernández-Martínez, Adán Peña-Barreto, T. Barrientos-Fortes, D. Álvarez-Hernández, S. Solano-Gálvez, R. Vázquez-López
Introduction: The microbiota is a community of microorganisms that live in a specific environment. Their type and number depend on multiple internal and external factors. Oral is the second most diverse and populated microbiota of the body. Smoking and vaping induce changes in its composition, and it has been demonstrated that they can lead to an increase in antimicrobial resistance. Objective: To compare the phenotypic profile of antimicrobial resistance in the oral microbiota of non-smokers, tobacco users, and electronic cigarette vapers. Methods: An observational, descriptive, cross-sectional, and comparative study was carried out. Three groups of non-smokers, smokers of conventional tobacco, and electronic cigarette (EC) vapers of tobacco flavored e-juice were formed. Oral cavity samples were obtained, incubated, and seeded in agar plates. Bacteria were isolated and identified performing Gram staining, oxidase, indole, and biochemical test panels. Susceptibility tests were performed using a MicroScan autoSCAN-4 system and the Kirby–Bauer test. Results: Variation was observed in the populations of bacteria that were isolated in each of the groups, but the non-smokers showed the most pathogens. In the non-smoking group, Staphylococcus sciuri was the most common bacteria, Staphylococcus sciuri and Enterobacter cloacae were the most abundant in the smoking group, and in the EC vapers group, the most common bacteria were Staphylococcus epidermidis and Staphylococcus sciuri. Conclusion: Multidrug resistance was observed in all the groups. However, EC vapers showed the highest proportions of antimicrobial resistance, raising a major concern.
{"title":"Comparison of the phenotypic profile of antimicrobial resistance in the oral microbiota of non-smokers, tobacco smokers, and electronic cigarette vapers - A pilot study","authors":"E. Martínez-Solís, Abraham Atman Hernández-Martínez, Adán Peña-Barreto, T. Barrientos-Fortes, D. Álvarez-Hernández, S. Solano-Gálvez, R. Vázquez-López","doi":"10.36105/PSRUA.2021V1N1.01","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N1.01","url":null,"abstract":"Introduction: The microbiota is a community of microorganisms that live in a specific environment. Their type and number depend on multiple internal and external factors. Oral is the second most diverse and populated microbiota of the body. Smoking and vaping induce changes in its composition, and it has been demonstrated that they can lead to an increase in antimicrobial resistance. Objective: To compare the phenotypic profile of antimicrobial resistance in the oral microbiota of non-smokers, tobacco users, and electronic cigarette vapers. Methods: An observational, descriptive, cross-sectional, and comparative study was carried out. Three groups of non-smokers, smokers of conventional tobacco, and electronic cigarette (EC) vapers of tobacco flavored e-juice were formed. Oral cavity samples were obtained, incubated, and seeded in agar plates. Bacteria were isolated and identified performing Gram staining, oxidase, indole, and biochemical test panels. Susceptibility tests were performed using a MicroScan autoSCAN-4 system and the Kirby–Bauer test. Results: Variation was observed in the populations of bacteria that were isolated in each of the groups, but the non-smokers showed the most pathogens. In the non-smoking group, Staphylococcus sciuri was the most common bacteria, Staphylococcus sciuri and Enterobacter cloacae were the most abundant in the smoking group, and in the EC vapers group, the most common bacteria were Staphylococcus epidermidis and Staphylococcus sciuri. Conclusion: Multidrug resistance was observed in all the groups. However, EC vapers showed the highest proportions of antimicrobial resistance, raising a major concern.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126465499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-22DOI: 10.36105/PSRUA.2021V1N1.06
Felix León-Avila, Galit Wohlmuth-Cohen, Ana Cristina Suárez-Espinosa, Alejandra De la Cruz-Romano, Jimena Figueroa-Valero
In a matter of months, COVID-19 has spread worldwide, and it has affected not only human lives but also the socioeconomic structure. Disease severity increases with the presence of other factors such as age, diabetes, and hypertension. Exercise has been shown to control blood pressure and blood sugar level; it enhances the immune system and age-related physiological changes. Given its ability to control all of these factors, exercise can be used as a protective agent against disease severity in COVID-19 and as treatment during subsequent rehabilitation.
{"title":"Can exercise be used as a protective agent against disease severity in COVID-19 and as treatment during subsequent rehabilitation?","authors":"Felix León-Avila, Galit Wohlmuth-Cohen, Ana Cristina Suárez-Espinosa, Alejandra De la Cruz-Romano, Jimena Figueroa-Valero","doi":"10.36105/PSRUA.2021V1N1.06","DOIUrl":"https://doi.org/10.36105/PSRUA.2021V1N1.06","url":null,"abstract":"In a matter of months, COVID-19 has spread worldwide, and it has affected not only human lives but also the socioeconomic structure. Disease severity increases with the presence of other factors such as age, diabetes, and hypertension. Exercise has been shown to control blood pressure and blood sugar level; it enhances the immune system and age-related physiological changes. Given its ability to control all of these factors, exercise can be used as a protective agent against disease severity in COVID-19 and as treatment during subsequent rehabilitation.","PeriodicalId":125514,"journal":{"name":"Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128637771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：