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[Alcohol drinking as a risk factor for cancer]. [饮酒是患癌症的危险因素]。
Keitaro Matsuo
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引用次数: 0
Gastric glomus tumor diagnosed by endoscopic ultrasound-guided fine-needle aspiration biopsy: report of a case.
Pub Date : 2014-04-25 DOI: 10.15017/1456032
Y. Minoda, K. Akahoshi, M. Oya, M. Kubokawa, Y. Motomura, Kazuhiko Nakamura
A glomus tumor of the stomach is rare. It is difficult to diagnose the tumor before surgery by only endoscopic biopsy and radiography, and there is no established method of diagnosis before surgical treatment. Esophagogastroduodenoscopy (EGD) on a 50-year-old Japanese woman revealed a 10 mm submucosal tumor in the anterior wall of the gastric angle. Follow-up EGD revealed an increase in the size of the tumor to 15mm. Endoscopic ultrasonography (EUS) demonstrated a 15mm subepithelial hypoechoic solid tumor with continuity to the proper muscle layer. Histologic diagnosis by endoscopic ultrasonography guided fine needle aspiration (EUS-FNA) was glomus tumor. The tumor was treated by laparoscopic local resection. The histologic diagnosis of the resected tumor was similar to the preoperative EUS-FNA results. EUS-FNA would appear to be an effective histologic test for early diagnosis of gastric glomus tumor.
胃球囊瘤是罕见的。术前仅通过内镜活检和x线摄影很难诊断肿瘤,且术前没有确定的诊断方法。食管胃十二指肠镜检查(EGD)发现胃角前壁有一个10毫米的粘膜下肿瘤。随访EGD显示肿瘤增大至15mm。超声内镜(EUS)显示一个15mm的上皮下低回声实体瘤,并延及固有肌肉层。超声内镜引导下细针穿刺(EUS-FNA)病理诊断为血管球瘤。经腹腔镜局部切除治疗。切除肿瘤的组织学诊断与术前EUS-FNA结果相似。EUS-FNA是早期诊断胃球囊瘤的有效组织学检查。
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引用次数: 6
A rare case of a bronchial anomaly running in the hilar region from the right lower lobe to the middle lobe. 一例罕见的支气管异常在肺门区运行从右下叶到中叶。
Pub Date : 2014-04-25 DOI: 10.15017/1448972
T. Fujishita, T. Okamoto, Yuzo Suzuki, Hirokazu Kitahara, S. Shimamatsu, M. Kohno, Y. Morodomi, D. Kawano, Y. Matsuo, H. Honda, Y. Maehara
A 77-year-old male was referred to our department due to lung cancer (cT3N0M0) of the right lower lobe. During right lower lobectomy, a thin duct structure was recognized in the hilar region between the middle and lower lobes that was identified to be a supernumerary bronchus upon a review of the preoperative chest CT images. Although bronchial anomalies are rare, it is important to carefully view preoperative images for any such anomalies in order to more safely perform surgery.
一位77岁男性患者因右下肺叶肺癌(cT3N0M0)转介至我科。在右下肺叶切除术中,经术前胸部CT检查,发现肺门区中下肺叶之间有一薄导管结构,确认为多余支气管。虽然支气管异常是罕见的,但为了更安全地进行手术,仔细查看任何此类异常的术前图像是很重要的。
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引用次数: 1
Gastric glomus tumor diagnosed by endoscopic ultrasound-guided fine-needle aspiration biopsy: report of a case. 超声内镜引导下细针穿刺活检诊断胃球囊瘤1例。
Yosuke Minoda, Kazuya Akahoshi, Masafumi Oya, Masaru Kubokawa, Yasuaki Motomura, Kazuhiko Nakamura

A glomus tumor of the stomach is rare. It is difficult to diagnose the tumor before surgery by only endoscopic biopsy and radiography, and there is no established method of diagnosis before surgical treatment. Esophagogastroduodenoscopy (EGD) on a 50-year-old Japanese woman revealed a 10 mm submucosal tumor in the anterior wall of the gastric angle. Follow-up EGD revealed an increase in the size of the tumor to 15mm. Endoscopic ultrasonography (EUS) demonstrated a 15mm subepithelial hypoechoic solid tumor with continuity to the proper muscle layer. Histologic diagnosis by endoscopic ultrasonography guided fine needle aspiration (EUS-FNA) was glomus tumor. The tumor was treated by laparoscopic local resection. The histologic diagnosis of the resected tumor was similar to the preoperative EUS-FNA results. EUS-FNA would appear to be an effective histologic test for early diagnosis of gastric glomus tumor.

胃球囊瘤是罕见的。术前仅通过内镜活检和x线摄影很难诊断肿瘤,且术前没有确定的诊断方法。食管胃十二指肠镜检查(EGD)发现胃角前壁有一个10毫米的粘膜下肿瘤。随访EGD显示肿瘤增大至15mm。超声内镜(EUS)显示一个15mm的上皮下低回声实体瘤,并延及固有肌肉层。超声内镜引导下细针穿刺(EUS-FNA)病理诊断为血管球瘤。经腹腔镜局部切除治疗。切除肿瘤的组织学诊断与术前EUS-FNA结果相似。EUS-FNA是早期诊断胃球囊瘤的有效组织学检查。
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引用次数: 0
[Individualized immunosuppressive therapy after liver transplantation focusing on detoxifying mechanisms]. 【肝移植后个体化免疫抑制治疗关注解毒机制】。
Satohiro Masuda
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引用次数: 0
A rare case of a bronchial anomaly running in the hilar region from the right lower lobe to the middle lobe. 一例罕见的支气管异常在肺门区运行从右下叶到中叶。
Takatoshi Fujishita, Tatsuro Okamoto, Yuzo Suzuki, Hirokazu Kitahara, Shinichiro Shimamatsu, Mikihiro Kohno, Yosuke Morodomi, Daigo Kawano, Yoshio Matsuo, Hiroshi Honda, Yoshihiko Maehara

A 77-year-old male was referred to our department due to lung cancer (cT3N0M0) of the right lower lobe. During right lower lobectomy, a thin duct structure was recognized in the hilar region between the middle and lower lobes that was identified to be a supernumerary bronchus upon a review of the preoperative chest CT images. Although bronchial anomalies are rare, it is important to carefully view preoperative images for any such anomalies in order to more safely perform surgery.

一位77岁男性患者因右下肺叶肺癌(cT3N0M0)转介至我科。在右下肺叶切除术中,经术前胸部CT检查,发现肺门区中下肺叶之间有一薄导管结构,确认为多余支气管。虽然支气管异常是罕见的,但为了更安全地进行手术,仔细查看任何此类异常的术前图像是很重要的。
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引用次数: 0
[Case of pulmonary inflammatory pseudotumor with cysts]. 肺炎性假瘤伴囊肿1例。
Masakazu Katsura, Hirokazu Kitahara, Yosuke Morodomi, Daigo Kawano, Takaomi Koga, Toshiya Furuta, Tatsuro Okamoto, Yoshinao Oda, Yoshihiko Maehara

We herein report a case involving a 58-year-old female patient with multiple cystic lesions in the right lobe of the lung. The lesions were revealed on chest computed tomography in 2002 and followed up. Transbronchial lung biopsy showed no malignancy in June 2013. The lesions gradually increased in size and thickness and were associated with fluid-filled cysts. We performed a right lower lobectomy in November 2013. Pathological examination revealed inflammatory pseudotumor. Such a case of inflammatory pseudotumor presenting as a pulmonary cyst has not been previously described. Intractable infection and inflammation are regarded as common causes of inflammatory pseudotumor. This condition should be considered in patients with a medical history consistent with infectious disease and a pulmonary cyst found on chest computed tomography.

我们在此报告一例58岁女性患者,右肺多囊性病变。病变于2002年胸部电脑断层扫描发现并随访。2013年6月经支气管肺活检未见恶性肿瘤。病变的大小和厚度逐渐增大,并伴有充满液体的囊肿。2013年11月,我们进行了右下肺叶切除术。病理检查显示炎性假瘤。这种炎症性假肿瘤表现为肺囊肿的病例以前没有被描述过。顽固性感染和炎症被认为是炎性假瘤的常见原因。在病史符合传染病和胸部计算机断层扫描发现肺囊肿的患者中,应考虑这种情况。
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引用次数: 0
[Personalized medicine in non-small-cell carcinoma]. [非小细胞癌的个体化治疗]。
Eiji Iwama, Koichi Takayama, Eishi Baba, Yoichi Nakanishi
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引用次数: 0
[Case report of introducing MMF and steroids as an immunosuppressive therapy after living-donor liver transplantation for a patient with the diabetic nephropathy]. [1例糖尿病肾病患者活体肝移植后引入MMF和类固醇作为免疫抑制治疗的病例报告]。
Shotaro Kuramitsu, Tomohiro Iguchi, Mizuki Ninomiya, Yo-ichi Yamashita, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Tomoharu Yoshizumi, Yuji Soejima, Ken Shirabe, Hirofumi Kawanaka, Tetsuo Ikeda, Toshiya Furuta, Ryuichiro Tamada, Yoshihiko Maehara

Calcineurin inhibitor (CNI) combined with mycophenolate mofetil (MMF) and steroid is mainly used as immunosuppressive therapy after the living-donor liver transplantation (LDLT). However, the nephrotoxicity caused by CNI remains a critical problem for patients with chronic renal failure, especially on early postoperative period. A 62-year-old woman with decompensated liver cirrhosis secondary to hepatitis B (Child-Pugh C, MELD score 11 points) and chronic renal failure due to diabetic nephropathy (Cr 1.56 mg/dl, GFR 27 ml/min/1.73 m2) experienced LDLT. During the reconstruction of hepatic vein, the supra-and infra-hepatic vena cava was totally clamped. The estimated right lobe liver graft volume was 540 g, representing 51.3% of the standard liver volume of the recipient. Because of the perioperative renal dysfunction due to diabetic nephropathy and the total clamping the vena cava which induced the congestion kidney, MMF (1500 mg/day) and steroid (250 mg/day converted into predonisolone) were mainly introduced as an immunosuppressive therapy after LDLT. The low-dose CNI, tacrolimus also induced the nephrotoxicity and was given for only a short time. Finally, according to the postoperative renal function, the low-dose CNI, cyclosporin (50 mg/day) was able to be added to the introduced immunosuppressive therapy. After having left the hospital, MMF (1500 mg/day), steroid (20 mg/day converted into predonisolone) and cyclosporin (75 mg/day) continued to be given as the immunosuppressive therapy and neither acute graft rejection nor drug-induced renal dysfunction was occurred. This is a case report of introducing with mainly MMF and steroid as an immunosuppressive therapy after LDLT for a patient with perioperative renal dysfunction.

钙调磷酸酶抑制剂(CNI)联合霉酚酸酯(MMF)和类固醇主要用于活体肝移植(LDLT)后的免疫抑制治疗。然而,CNI引起的肾毒性仍然是慢性肾功能衰竭患者的一个关键问题,特别是在术后早期。一名62岁女性,继发于乙型肝炎失代偿性肝硬化(Child-Pugh C, MELD评分11分)和糖尿病肾病引起的慢性肾功能衰竭(Cr 1.56 mg/dl, GFR 27 ml/min/1.73 m2),经历了LDLT。重建肝静脉时,完全夹住肝上腔静脉和肝下腔静脉。估计右叶肝移植体积为540 g,占受体标准肝脏体积的51.3%。由于糖尿病肾病围手术期肾功能不全及腔静脉完全夹闭导致肾充血,在LDLT术后主要采用MMF (1500mg /d)和类固醇(250mg /d转化为强的松龙)作为免疫抑制治疗。小剂量CNI、他克莫司也有肾毒性,且给药时间短。最后,根据术后肾功能情况,在引入免疫抑制治疗的基础上,可添加低剂量的CNI,环孢素(50 mg/天)。出院后继续给予MMF (1500mg /d)、类固醇(20mg /d转化为强的松龙)和环孢素(75mg /d)作为免疫抑制治疗,未发生急性移植排斥反应和药物性肾功能障碍。本文报告一例肾功能不全患者行LDLT后主要采用MMF和类固醇作为免疫抑制治疗。
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引用次数: 0
[Case of obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome]. [半阴道梗阻性伴同侧肾异常综合征1例]。
Keiko Horioka, Keiko Kataoka, Hiroko Ooishi, Ryousuke Tsunematsu, Kaoru Okugawa, Hiroaki Kobayashi, Kiyoko Kato

We report the case of 23 year-old woman with OHVIRA syndrome (obstructed hemivagina and ipisilateral renal anomaly) discovered during management for right renal failure. Non-specific symptoms such as lower abdominal pain, dysmenorrhea, and genital bleeding sometimes occur with congenital uterine anomalies such as this. It is very difficult to diagnose OHVIRA syndrome accurately without ultrasound and magnetic resonance imaging, and patients can develop severe complications as a result of delays in diagnosis: endometriosis, pelvic adhesions, or infertility can occur through backflow of genital bleeding because of vaginal septum. In our patient we managed to avoid severe complications by surgically resecting the vaginal septum. She was treated within an appropriate time frame and without complications. Fortunately, after the surgery she managed to become pregnant in the left side of the uterus.

我们报告一例23岁女性OHVIRA综合征(半阴道梗阻性和同侧肾异常)在治疗右肾衰竭时被发现。先天性子宫异常有时会出现下腹痛、痛经和生殖器出血等非特异性症状。在没有超声和磁共振成像的情况下,很难准确诊断OHVIRA综合征,并且由于诊断的延迟,患者可能会出现严重的并发症:子宫内膜异位症、盆腔粘连,或因阴道间隔导致生殖器出血回流而导致不孕。在我们的病人中,我们通过手术切除阴道隔膜避免了严重的并发症。她在适当的时间内接受了治疗,没有出现并发症。幸运的是,手术后,她成功地在子宫左侧怀孕。
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Fukuoka igaku zasshi = Hukuoka acta medica
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