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Correlation of Whole Blood Cell Morphology on Electrical Impedance Spectroscopic Characteristics on the Severity Level of Ischemic Stroke Patients 缺血性脑卒中患者全血细胞形态学与电阻抗频谱特征严重程度的相关性
Pub Date : 2023-11-30 DOI: 10.32996/ijbpcs.2023.5.2.5
Ferhiyan Nabila, C. Widodo, Didik Rahadi Santoso
This paper discusses the influence of peripheral blood smear morphology methods on the electrical impedance spectroscopic characteristics of blood samples from ischemic stroke patients. In this study, there were 26 blood samples, consisting of a control group with 5 blood samples and a group of ischemic stroke patients with 21 samples with varying degrees of severity. The methods used are electrical impedance spectroscopy (EIS) and whole blood cell morphology methods. The EIS method was carried out using the BISDAQ tool and application, and results were obtained in the form of Bode Plot, Bode Phase Plot, Nyquist Plot, and measurement data values in the form of Ms. Excel. Meanwhile, the Morphological method is carried out by making a peripheral blood smear, then viewing and obtaining an image using a digital microscope, and then counting the number of cells using the Image Raster application. Based on the results of the method carried out, the correlation can be seen to conclude that whole blood cell morphology greatly influences the characteristics of EIS and determines the severity of ischemic stroke patients.
本文讨论了外周血涂片形态学方法对缺血性中风患者血液样本电阻抗光谱特性的影响。本研究共收集了 26 份血液样本,其中对照组 5 份,缺血性脑卒中患者组 21 份,患者病情轻重不一。采用的方法是电阻抗光谱法(EIS)和全血细胞形态学法。电阻抗光谱法使用 BISDAQ 工具和应用程序,结果以 Bode Plot、Bode Phase Plot、Nyquist Plot 的形式获得,测量数据值以 Ms.同时,形态学方法是通过制作外周血涂片,然后使用数码显微镜观察并获取图像,再使用图像栅格应用程序计算细胞数量。根据该方法的结果,可以得出相关结论:全血细胞形态在很大程度上影响着 EIS 的特征,并决定着缺血性脑卒中患者的严重程度。
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引用次数: 0
The Investigating of the Effect of Magnetic Field on a Flint Glass for Optical Isolators Applications 磁场对用于光隔离器的燧石玻璃影响的研究
Pub Date : 2023-08-20 DOI: 10.32996/ijbpcs.2023.5.2.2
Khudaidad Wasiq, Mohammad Tayeeb Qurdash
In this study, the effect of a magnetic field on a Flint Glass for optical isolator applications has been reported. A flint glass and a laser light source with a wavelength of 650nm were used as a medium and a light source, respectively. The magnetic field was produced by applying a current through a coil. The linearly polarized light was passed through the medium in the presence of a magnetic field, and the angle of rotation was measured. The angle of rotation was plotted versus magnetic field strength and fitted linearly. The experimental results showed that the flint glass becomes optically active in the presence of a magnetic field because it rotates the plane of linearly polarized light, and this rotation increases with respect to the magnetic field linearly. The Verdet constant was calculated  for 650nm, which is a large coefficient for the rotation of the plane of polarized light.
本研究报道了磁场对用于光隔离器的燧石玻璃的影响。实验以燧石玻璃为介质,以波长为650nm的激光光源为光源。磁场是通过给线圈通电而产生的。线偏振光在磁场作用下通过介质,测量其旋转角度。旋转角度与磁场强度的关系是线性拟合的。实验结果表明,在磁场作用下,燧石玻璃由于使线偏振光平面旋转而具有光学活性,并且这种旋转相对于磁场呈线性增加。在650nm处计算Verdet常数,对于偏振光的平面旋转来说,这是一个很大的系数。
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引用次数: 0
GC-MS and LC-MS/MS Analysis of Secondary Metabolites in the Methanolic Extract of Uncaria callophylla Blume ex Korth. Stems 黄钩藤甲醇提取物中次生代谢产物的GC-MS和LC-MS/MS分析。茎
Pub Date : 2023-08-15 DOI: 10.32996/ijbpcs.2023.5.2.1
Astri Rozanah Siregar, Syafira Soraya, E. Sinaga
Uncaria callophylla Blume ex Korth. is a wild plant species belonging to the Rubiaceae family. These plants thrive in the peat swamp forest of Kalimantan, Indonesia. The stems of Uncaria callophylla have been used by the Dayak Ngaju tribe to treat various diseases and to restore stamina while they work in the forest. The present study was conducted to identify the secondary metabolites in the methanolic extract of Uncaria callohylla stems to increase the knowledge about this plant and its potential in medicinal applications and drug discovery. The analysis was conducted using GC-MS and LC-MS/MS. GC-MS analysis was performed with the Agilent Technologies 7890 Gas Chromatography equipped with an Auto Sampler and 5975 Mass Selective Detector. The LC-MS analysis was carried out in the C18 column of the Waters Acquity UPLC system. MS analysis was performed with an electrospray ionization source (ESI) in positive and negative ion modes, and the compounds were identified using a UNIFI data processor with a mass spectrum library of natural active substances from the Waters Traditional Medical Scientific Library database based on UPLC/QTof MSE Data Acquisition. GC-MS analysis revealed the presence of 24 peaks, and nine of them showed quality 90% or higher, namely n-Hexadecanoic acid (16.63%), 1,3,7-Trimethyl-3,7-Dihydro-1H-Purine-2,6-Dione (13.07%), Hexadecanoic Acid, Methyl Ester; 1,2-Benzenedicarboxylic Acid, Diethyl Ester; 9,12-Octadecadienoic Acid, Methyl Ester; Methyl 14-Methylheptadecanoate; (9E,12E)-9,12-Octadecadienoic Acid; Z, E-3,13-Octadecadien-1-o1; and 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexanethyl-, (all-E)-. LC-MS/MS analysis revealed the presence of five compounds, namely Arecatannin A1, Sweroside_2, Uncarine A, Epianhydrobelachinal, and Betulonic acid. All the secondary metabolites identified from GC-MS and LC-MS/MS analysis have biological activity, which indicates their medicinal potencies. From the result, it can be concluded that Uncaria callophylla stem methanolic extract contains various bioactive compounds justifies its traditional use, and therefore it can be developed further for new drug discovery.
鸡翅钩藤(Uncaria callophylla Blume)是茜草科的一种野生植物。这些植物在印度尼西亚加里曼丹的泥炭沼泽森林中茁壮成长。在达雅克·恩加朱部落,当他们在森林里工作时,钩藤的茎被用来治疗各种疾病和恢复体力。本研究旨在鉴定钩藤(Uncaria callohylla)茎甲醇提取物中的次生代谢物,以增加对该植物的认识及其在药用和药物开发方面的潜力。采用GC-MS和LC-MS/MS进行分析。采用配备自动进样器和5975质量选择检测器的Agilent Technologies 7890气相色谱仪进行GC-MS分析。采用Waters Acquity UPLC系统的C18柱进行LC-MS分析。采用电喷雾电离源(ESI)在正离子和负离子模式下进行质谱分析,采用UNIFI数据处理器和基于UPLC/QTof MSE数据采集的Waters Traditional Medical Scientific library数据库中的天然活性物质质谱库对化合物进行鉴定。GC-MS分析共发现24个峰,其中9个峰的质量为90%及以上,分别为正十六酸(16.63%)、1,3,7-三甲基-3,7-二氢- 1h -嘌呤-2,6-二酮(13.07%)、十六酸甲酯;1,2-苯二甲酸二乙酯;9,12-十八二烯酸甲酯;甲基14-Methylheptadecanoate;(9 e, 12 e) 9日12-Octadecadienoic酸;13-Octadecadien-1-o1 Z, e - 3;2,6、10、14、18、22-四碳六烯,2,6、10、15、19、23-己基-,(全e)-。LC-MS/MS分析结果显示,其中含有槟酒素A1、Sweroside_2、Uncarine A、Epianhydrobelachinal和桦木酸5种化合物。GC-MS和LC-MS/MS分析鉴定的次生代谢物均具有生物活性,说明其具有一定的药用价值。结果表明,甲壳钩藤茎甲醇提取物中含有多种生物活性成分,证明了其传统用途是合理的,因此可以进一步开发用于新药开发。
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引用次数: 0
The Study of ZnO-NRs and Ge-chips Bandgaps for the Elimination of Elemental Semiconductors and Compound Semiconductors Applications ZnO-NRs和ge芯片带隙消除元素半导体和化合物半导体应用的研究
Pub Date : 2023-05-29 DOI: 10.32996/ijbpcs.2023.5.1.3
Mohammad Mohsen Hewadmal, Mujibullah Mahboob, Sayed Abdul Saboor Mosamem
In this paper, the bandgap of Germanium (Ge) and Zinc-Oxid (ZnO) materials were studied using two different techniques called the four-probe method and UV-Visible spectroscopy. A chip of Ge and a ZnO synthesized Nanorods on the FTO substrate were utilized as the samples. Scanning electron microscopy and X-ray diffraction spectroscopy were applied to understand the morphology and the crystal structure of the ZnO particles on the substrate. To get bandgap for Ge, the variation of voltage concerning temperature in  current was recorded, and for ZnO- Nanorods (NRs), the absorption spectra in the range of (200-800) nm were taken. Based on obtained data and calculations, the band gap of Ge and ZnO-NRs were determined to be around  and  respectively. It revealed that the bandgap of compound semiconductors (ZnO- NRs) could be sufficiently large as compared to the elemental semiconductors (Ge), and through that, the modification of various devices is possible in the industry.
本文采用四探针法和紫外-可见光谱法研究了锗(Ge)和氧化锌(ZnO)材料的带隙。在FTO衬底上制备了Ge纳米棒和ZnO纳米棒作为样品。利用扫描电子显微镜和x射线衍射光谱分析了基体上ZnO颗粒的形貌和晶体结构。为了得到Ge的带隙,记录了电压随温度在电流中的变化,并对ZnO-纳米棒(NRs)进行了(200-800)nm范围内的吸收光谱。根据得到的数据和计算,确定了Ge和ZnO-NRs的带隙分别在和附近。结果表明,与单质半导体(Ge)相比,复合半导体(ZnO- NRs)的带隙足够大,从而为工业上各种器件的改造提供了可能。
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引用次数: 0
Determination of the Optimum Operating Conditions for Integrated Methanol and Ethanol Plant from Natural Gas Reactors 天然气反应器甲醇乙醇一体化装置最佳操作条件的确定
Pub Date : 2023-04-03 DOI: 10.32996/ijbpcs.2023.5.1.2
Dimas Laksana Yudharaputra, Sanggono Adisasmito
Methanol and ethanol can be produced from many kinds of feedstock. One of the most preferred methods to synthesize methanol is from natural gas, which is reformed to form synthesis gas (syngas) and converted by a catalyst to form methanol. Conversely, ethanol production mostly comes from biomass, which competes with human food fulfilment. Several pieces of literature conduct syngas transformation to ethanol to solve this problem. However, the experiment is conducted on a lab scale or pilot scale. Before the technology can be mass-produced on a plant scale, we must determine the most suitable operating condition for the reactor to escalate the reactor's productivity. This study is aimed to determine the optimal operating condition for the integrated methanol and ethanol plant, which is the reactors. The software used for the study is Aspen Plus V12.1. The independent variables for all the reactors in this study are the pressure (P) and the temperature (T). We add the feed molar flow ratio as the independent variable for the Steam Methane Reforming (SMR) and the ethanol synthesis reactor. The dependent variable that will be used for the determination of the optimal operating condition of the reactors is the reactant conversion and the product yield. The data validation between the experimental data conducted by other authors and the process modeling result is in good agreement with less than 6% of error for all three reactors. After performing the process simulation and sensitivity analysis to determine the optimal operating condition for the reactors, it is found that the optimal operating condition for the reactors is as follows: (1) SMR reactor: 25 bar pressure, 1,223 K temperature, feed molar flow ratio (H2O/CH4 ratio) of 3, (2) methanol synthesis reactor: 100 bar pressure and 503 K temperature, and (3) ethanol synthesis reactor:110 bar pressure, 583 K temperature, and feed molar flow ratio (H2/CO ratio) of 0.75.
甲醇和乙醇可以由多种原料生产。合成甲醇最优选的方法之一是天然气,天然气经重整形成合成气(syngas),再经催化剂转化生成甲醇。相反,乙醇生产主要来自生物质,这与人类的食物供应竞争。有几篇文献通过合成气转化为乙醇来解决这一问题。然而,该实验是在实验室规模或试点规模上进行的。在该技术可以在工厂规模上大规模生产之前,我们必须确定最适合反应堆的操作条件,以提高反应堆的生产率。本研究旨在确定甲醇乙醇一体化装置的最佳操作条件,即反应器。该研究使用的软件是Aspen Plus V12.1。本研究中所有反应器的自变量均为压力(P)和温度(T),并将进料摩尔流量比作为蒸汽甲烷重整(SMR)和乙醇合成反应器的自变量。用于确定反应器最佳操作条件的因变量是反应物转化率和生成物收率。其他作者的实验数据与过程建模结果的数据验证吻合良好,三个反应器的误差均小于6%。通过过程模拟和灵敏度分析确定反应器的最佳运行条件,发现反应器的最佳运行条件为:(1)SMR反应器:压力25 bar,温度1223 K,进料摩尔流量比(H2O/CH4比)为3;(2)甲醇合成反应器:压力100 bar,温度503 K;(3)乙醇合成反应器:压力110 bar,温度583 K,进料摩尔流量比(H2/CO比)为0.75。
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引用次数: 0
Total Phenolic and Total Flavonoid Content, Antioxidant Activity, and Nutritional Profile of Ziziphus mauritiana Fruit Juice 毛里求斯酸枣果汁中总酚和总黄酮含量、抗氧化活性及营养成分
Pub Date : 2023-03-02 DOI: 10.32996/ijbpcs.2023.5.1.1
Hanifa Nur Adilah, M. I. Saleh, Novia Deliasari Aliyya Az-Zahra, Eun-Mi Cho, E. Sinaga
Ziziphus mauritiana is a plant species belonging to the Rhamnaceae family. It is commonly found in tropical and subtropical regions of Asia, and in Indonesia, this plant grows wild and thrives on the islands of Bali, Lombok and Sumbawa. The fruits of Z. mauritiana are edible, however, in Indonesia, it is underutilized and has very low economic value. To evaluate its possibility to be developed as a functional food, this study was conducted to determine the total phenolics and flavonoids, dietary fiber, and nutrients contained in the fruit juice of Ziziphus mauritiana. Total phenols and flavonoids contents were determined using Folin Ciocalteu and AlCl3 methods, respectively. The in vitro antioxidant activity of the juice was evaluated using the DPPH method. The content of soluble and insoluble dietary fiber was determined using the standard AOAC analysis method, and proximates analysis was conducted in accordance with SNI 01-2891-1992.  The results of this study revealed that freeze-dried juice of Z. mauritiana fruit has total phenols content of 1690 mg GAE/100g, total flavonoids of 15.10 mg QE/100g, soluble dietary fiber of 0.61%, and insoluble dietary fiber 2.03%. However, the antioxidant activity of Ziziphus mauritiana fruit juice was weak with IC50 328.54 ppm. The proximate analysis revealed the crude fiber in the freeze-dried fruit juice was 0.56%, carbohydrates 82.43%, protein 3.34%, fats 0.31%, ash 3.62%, and water 10.30%. In conclusion, Ziziphus mauritiana fruit juice has a high content of total phenolic substances, high dietary fiber, and high nutritional value, therefore it has a good potential to be developed as a functional food.
毛里沙普是鼠李科的一种植物。它常见于亚洲的热带和亚热带地区,在印度尼西亚,这种植物生长在巴厘岛、龙目岛和松巴哇岛上。Z. mauritiana的果实是可食用的,然而,在印度尼西亚,它没有得到充分利用,经济价值很低。为了评估其作为功能性食品开发的可能性,本研究测定了毛里求斯酸枣果汁中总酚类、总黄酮、膳食纤维和营养成分的含量。采用Folin Ciocalteu法和AlCl3法测定总酚和总黄酮含量。采用DPPH法评价其体外抗氧化活性。采用标准AOAC分析方法测定可溶性和不可溶性膳食纤维含量,并按照SNI 01-2891-1992进行近似分析。结果表明,毛里亚果冻干汁中总酚含量为1690 mg GAE/100g,总黄酮含量为15.10 mg QE/100g,可溶性膳食纤维含量为0.61%,不溶性膳食纤维含量为2.03%。而毛里求斯酸枣果汁的抗氧化活性较弱,IC50为328.54 ppm。近似分析表明,冻干果汁的粗纤维含量为0.56%,碳水化合物含量为82.43%,蛋白质含量为3.34%,脂肪含量为0.31%,灰分含量为3.62%,水分含量为10.30%。综上所述,毛里求斯酸枣果汁中总酚类物质含量高,膳食纤维含量高,营养价值高,具有很好的功能性食品开发潜力。
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引用次数: 3
Calculation of the Chemical Shift of N-15 by Quantum Mechanics 用量子力学计算N-15的化学位移
Pub Date : 2022-11-22 DOI: 10.32996/ijbpcs.2022.4.2.5
Emad A. S. Al-Hyali, Yosef Othman Al-Jobure
This study aims to develop a new set of added variables to calculate the chemical shift N-15 based on quantum mechanics methods for a number of periodic compounds using theoretical chemistry (Gaussian V.12, 2010). The relationship between the experimental N-15 was conducted with two mechanical variables, such as SPSS V 2019. The relationship between the theoretical chemical shift values ​​of the N-15 atom nucleus and practical values ​​in literature was examined. Two quantitative mechanical methods are used to extract information to calculate the N-15 chemical shift, the traditional method, the other AB Initio method, and the DFT job theory. The success of the method is determined in terms of the values ​​of the correlation coefficient (R) and the standard error (SE), as well as the material meaning of the specified variables. A good consensus is seen between practical and theoretical values. A comparison was made between the two methods to find out the best in the chemical transformation account. The DFT method gave better results.
本研究旨在利用理论化学(Gaussian V.12, 2010)开发一组新的附加变量,以基于量子力学方法计算一些周期性化合物的化学位移N-15。实验N-15与SPSS V 2019等两个力学变量之间的关系。研究了N-15原子核的理论化学位移值与文献中实际值之间的关系。利用两种定量力学方法提取信息计算N-15化学位移,即传统方法、另一种AB Initio方法和DFT作业理论。该方法的成功与否取决于相关系数(R)和标准误差(SE)的取值,以及指定变量的物质意义。实践值与理论值有很好的一致性。对两种方法进行了比较,找出了化学转化解释的最佳方法。DFT方法得到了较好的结果。
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引用次数: 0
Nanoparticle-induced Ferroptosis for Cancer Therapy 纳米颗粒诱导的铁下垂用于癌症治疗
Pub Date : 2022-09-28 DOI: 10.32996/ijbpcs.2022.4.2.4
Fiona Hammond Quarcoo, Gideon Appiah Kusi, Juliette C.N. Fouemina
Ferroptosis is a recently identified form of non-apoptotic regulated cell death (RCD). It is primarily characterized by the accumulation of lipid peroxide, which is iron-dependent. Ferroptosis is essential for the treatment of tumors, renal failure, and ischemia reperfusion exposure (IRI). Ferroptosis and nanomedicine are now the subjects of intense study and clinical attention. There is, however, a limited amount of data on the precise molecular pathways behind ferroptosis and the contribution of nanoparticles. This work provides a thorough overview of ferroptosis, its regulations, and the various mechanisms by which iron- and non-iron-based nanoparticles potentially trigger ferroptosis in the context of cancer therapy. We investigated the most recent developments in ferroptosis research and nanoparticles as ferrotosis-inducing agents by performing extensive literature studies based on the notion of ferroptosis and cancer therapy and a thorough examination of various publications regarding nanoparticles. Our results suggest that tumor suppression and treatment efficacy can both be enhanced by ferroptosis triggered via nanoparticles. New ideas and viewpoints have also been put out for the treatment of ferroptosis-induced cancer, which will make a significant contribution to cancer therapy.
铁下垂是最近发现的一种非凋亡调节细胞死亡(RCD)形式。它的主要特征是脂质过氧化积累,这是铁依赖的。铁下垂是必不可少的治疗肿瘤,肾功能衰竭,和缺血再灌注暴露(IRI)。铁下垂和纳米医学是目前研究和临床关注的热点。然而,关于铁下垂背后的精确分子途径和纳米颗粒的贡献的数据有限。这项工作提供了铁下垂的全面概述,其调控,以及各种机制,通过铁和非铁基纳米颗粒可能引发铁下垂在癌症治疗的背景下。我们调查了铁下垂研究和纳米颗粒作为铁下垂诱导剂的最新进展,基于铁下垂和癌症治疗的概念进行了广泛的文献研究,并对各种关于纳米颗粒的出版物进行了彻底的检查。我们的研究结果表明,纳米颗粒引发的铁下垂可以提高肿瘤抑制和治疗效果。对嗜铁性癌症的治疗也提出了新的思路和观点,将对癌症治疗做出重要贡献。
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引用次数: 0
Supplementation of Bouea macrophylla Fruit Juice Prevent Oxidative Stress in Rats Fed with High-Fat High-Cholesterol Diet through Attenuation of Lipid Peroxidation 补充大叶茯苓果汁可通过抑制脂质过氧化作用预防高脂高胆固醇饮食大鼠氧化应激
Pub Date : 2022-09-06 DOI: 10.32996/ijbpcs.2022.4.2.3
Alvira Noer Effendi, Mardian Iswahyudi, Eun-Mi Cho, S. Kumala, E. Sinaga
Fruits are rich in fiber and antioxidant compounds that can prevent and treat health disorders related to oxidative stress caused by high-fat high-cholesterol diet (HFHCD). Bouea macrophylla is a tropical fruit plant with edible juicy fruits. In this study, we conducted experiments to prove the effectiveness of B. macrophylla fruit juice (BMFJ) as an antioxidant agent in rats fed with HFHCD. Male Sprague Dawley rats were fed with HFHCD for 100 days and simultaneously orally supplemented with BMFJ. Atorvastatin was used as a positive control. At the end of the experiment, the blood and hepar were collected and assayed for malondialdehyde (MDA). The in vitro antioxidant activity of BMFJ was also evaluated using the DPPH method. Total phenols and flavonoids contents were determined using Folin Ciocalteu and AlCl3 methods, respectively. Results of the experiments showed that total phenols and flavonoids in BMFJ were 570 mg GAE/g and 31.89 mg QE/g, respectively, and the IC50 of radical scavenging activity was 564.271 ppm. The in vivo antioxidant evaluation showed that supplementation of BMFJ significantly prevents the increase of MDA levels, both in serum and liver of rats fed with HFHCD. These findings clearly indicate that supplementation of B. macrophylla fruit juice significantly prevents oxidative stress in rats fed with high-fat high-cholesterol diets through attenuation of lipid peroxidation.
水果富含纤维和抗氧化化合物,可以预防和治疗由高脂肪高胆固醇饮食引起的氧化应激相关的健康疾病。大叶菊是一种热带水果植物,果实多汁,可食用。在本研究中,我们通过实验证明了大叶B. macrophylla果汁(BMFJ)对HFHCD大鼠的抗氧化作用。雄性大鼠饲喂HFHCD 100 d,同时口服BMFJ。阿托伐他汀作为阳性对照。实验结束时,采集血液和肝脏,检测丙二醛(MDA)含量。采用DPPH法评价BMFJ的体外抗氧化活性。采用Folin Ciocalteu法和AlCl3法测定总酚和总黄酮含量。实验结果表明,BMFJ总酚和总黄酮含量分别为570 mg GAE/g和31.89 mg QE/g,清除自由基活性IC50为564.271 ppm。体内抗氧化评价表明,添加BMFJ可显著抑制HFHCD大鼠血清和肝脏中MDA水平的升高。这些研究结果清楚地表明,补充大叶青果汁可以通过抑制脂质过氧化作用,显著防止高脂高胆固醇饮食大鼠的氧化应激。
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引用次数: 1
Identification of Chemical Compounds in Ziziphus mauritiana Fruit Juice by GC-MS and LC-MS/MS Analysis GC-MS和LC-MS/MS分析毛里求斯紫枣果汁中的化学成分
Pub Date : 2022-09-05 DOI: 10.32996/ijbpcs.2022.4.2.2
Syafira Soraya, E. Sukara, E. Sinaga
Ziziphus mauritiana is an edible fruiting plant commonly found in Asia. In Indonesia, this plant grows wild and thrives on the islands of Bali, Lombok, and Sumbawa. Although it is edible and has good potential as food and medicinal ingredient, in Indonesia, the fruits of Z. mauritiana are underutilized and have almost no economic value. Information about the bioactivity and chemical content of the fruit is limited. To evaluate its possibility of being developed as functional food, a GC-MS and LC-MS/MS analysis was carried out to identify the phytochemical content of the fruit juice. From the GC-MS chromatogram, four compounds were identified with a quality match of 85% and above. The compounds were 5-( hydroxymethyl)-2–furancarboxaldehyde (43.45%), 5, 5'-(oxybis(methylene)) bis-2- furancarbox-aldehyde (25.99%), 2,3–dihydro-3,5–dihydroxy–6–methyl-4H–pyran–4-one (6.05%), and hexadecanoic acid (2.16%).   The result of the LC-MS/MS analysis showed 42 peaks of different chemical compounds and included several groups of compounds such as flavonoids, alkaloids, phenols, terpenoids, and organic acids. From these results, it can be concluded that Ziziphus mauritiana fruit juice contains various chemical compounds that are likely to have medicinal activity and therefore has good potential to be used and developed as a functional food.
毛里求斯紫茎是一种常见于亚洲的可食用果植物。在印度尼西亚,这种植物生长在巴厘岛、龙目岛和松巴哇岛上。虽然它是可食用的,作为食品和药用成分具有很好的潜力,但在印度尼西亚,Z. mauritiana的果实未被充分利用,几乎没有经济价值。关于这种水果的生物活性和化学成分的信息有限。为评价其开发为功能食品的可能性,采用气相色谱-质谱(GC-MS)和液相色谱-质谱联用(LC-MS/MS)对果汁中的植物化学成分进行了鉴定。从GC-MS图谱上,鉴定出4个化合物,质量匹配度在85%以上。化合物为5-(羟甲基)-2 -呋喃甲醛(43.45%)、5,5 '-(氧双(亚甲基))-2-呋喃甲醛(25.99%)、2,3 -二氢-3,5 -二羟基- 6 -甲基-4 -吡喃-4 -酮(6.05%)和十六烷酸(2.16%)。LC-MS/MS分析结果显示42个不同的化合物峰,包括黄酮类化合物、生物碱、酚类化合物、萜类化合物和有机酸等。综上所述,毛里求斯酸枣果汁中含有多种可能具有药用活性的化合物,具有很好的功能性食品开发利用潜力。
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引用次数: 4
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International Journal of Biological, Physical and Chemical Studies
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