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Analysis of the Relationship Between Self-Efficacy, Adherence With Diet Therapy and Fluid Control in Patients Receiving Hemodialysis Treatment: A Structural Equation Analysis 血液透析患者自我效能感、饮食治疗依从性和体液控制的关系分析:结构方程分析
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-07-07 DOI: 10.1111/hdi.70004
Gülcan Bahçecioğlu Turan, Ceren Karabulutlu, Zülfünaz Özer

Purpose

Hemodialysis treatment presents physical, emotional, and social challenges for patients, impacting their overall well-being and daily life. Successful management requires adherence to fluid restrictions, dietary guidelines, and regular medication intake. This study explored the associations between self-efficacy, dietary adherence, and fluid control in patients undergoing hemodialysis.

Methods

This cross-sectional, descriptive study was conducted from 15 April 2024 to 15 June 2024, involving 197 patients receiving hemodialysis at a public hospital and a private dialysis center in Erzurum, eastern Turkey. Data were collected using a Personal Information Form, the General Self-Efficacy Scale, the Fluid Control in Hemodialysis Patients Scale, and the Attitude Scale for Dietary Therapy of Hemodialysis Patients. Descriptive statistics and structural equation modeling were used for analysis. A Bayesian estimator assessed direct and indirect relationships between variables. The model's reliability and validity were assessed using various statistical tests.

Results

Participants had an average age of 53.3 years and an average duration on dialysis of 6.7 years. Of the participants, 91.4% regularly monitored their weight, and 65% regularly monitored edema. The average scores were 28.35 (5.92, SD) on the General Self-Efficacy Scale, 45.8 (8.12) on the Attitude Scale for Dietary Therapy, and 49.0 (9.05) on the Fluid Control Scale. Self-efficacy had a significant positive indirect association with fluid control through dietary adherence (β = 0.126, 95% confidence interval [0.008, 0.277]). The total association between self-efficacy and fluid control was also significant (β = 0.624, 95% confidence interval [0.483, 0.755]), with dietary adherence partially mediating this relationship. Self-efficacy accounted for 31% of the variance in dietary adherence, and the overall model explained 41% of the variance in fluid control.

Conclusion

Higher self-efficacy was associated with better dietary adherence and improved fluid control. Dietary adherence partially mediated the association between self-efficacy and fluid control. Healthcare providers may consider strategies to enhance self-efficacy in hemodialysis patients to support dietary adherence and fluid control, potentially improving treatment outcomes, and quality of life.

目的:血液透析治疗给患者带来身体、情感和社会方面的挑战,影响他们的整体健康和日常生活。成功的治疗需要坚持液体限制,饮食指南和定期药物摄入。本研究探讨了血液透析患者自我效能、饮食依从性和体液控制之间的关系。方法:这项横断面描述性研究于2024年4月15日至2024年6月15日进行,涉及197名在土耳其东部埃尔祖鲁姆一家公立医院和一家私立透析中心接受血液透析的患者。采用《个人信息表》、《一般自我效能感量表》、《血透患者体液控制量表》和《血透患者饮食治疗态度量表》进行数据收集。采用描述性统计和结构方程模型进行分析。贝叶斯估计器评估变量之间的直接和间接关系。采用各种统计检验对模型的信度和效度进行了评估。结果:参与者的平均年龄为53.3岁,平均透析时间为6.7年。在参与者中,91.4%定期监测体重,65%定期监测水肿。一般自我效能量表平均得分为28.35分(5.92,SD),饮食治疗态度量表平均得分为45.8分(8.12),体液控制量表平均得分为49.0分(9.05)。自我效能感与饮食依从性的流质控制呈正相关(β = 0.126, 95%可信区间[0.008,0.277])。自我效能感与液体控制之间的总关联也很显著(β = 0.624, 95%可信区间[0.483,0.755]),饮食依从性在其中起部分中介作用。自我效能感占饮食依从性差异的31%,整体模型解释了液体控制差异的41%。结论:较高的自我效能感与更好的饮食依从性和改善的体液控制有关。饮食依从性部分介导了自我效能感和体液控制之间的关联。医疗保健提供者可以考虑提高血液透析患者自我效能的策略,以支持饮食依从性和液体控制,潜在地改善治疗结果和生活质量。
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引用次数: 0
Mediating Effects of Fatigue and Sleep Quality on Uremic Pruritus and Quality of Life Among Hemodialysis Patients: A Cross-Sectional Study 疲劳和睡眠质量对血液透析患者尿毒症性瘙痒和生活质量的中介作用:一项横断面研究。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-30 DOI: 10.1111/hdi.70003
Yongjun Ji, Hye-Ja Park, Sunki Kim

Introduction

Uremic pruritus is a common and distressing symptom among patients undergoing hemodialysis, frequently accompanied by fatigue and poor sleep quality. These symptoms collectively impair quality of life (QoL), yet their interrelationships remain unclear. To examine whether fatigue and sleep quality mediate the relationship between uremic pruritus and QoL in hemodialysis patients.

Methods

A cross-sectional study using quantitative mediation analysis. A total of 175 hemodialysis patients from three hospital-affiliated dialysis centers in South Korea completed validated self-report measures assessing uremic pruritus, fatigue, sleep quality, and QoL. Mediation analysis was conducted using Baron and Kenny's framework, Sobel test, and bootstrapping.

Findings

Uremic pruritus was significantly correlated with fatigue (r = 0.30, p < 0.001) and sleep quality (r = 0.53, p < 0.001), and negatively correlated with QoL (r = −0.29, p < 0.001). Fatigue (B = −0.3, 95% CI: −0.5 to −0.1) and sleep quality (B = −0.2, 95% CI: −0.4 to −0.1) were significantly associated with both uremic pruritus and QoL. The final model accounted for 40% of the variance in QoL.

Conclusions

Uremic pruritus indirectly affects QoL through its impact on fatigue and sleep quality. This suggests that its influence operates via interconnected symptoms rather than directly. The findings support the need for integrated symptom management approaches in dialysis care. Interventions targeting fatigue and sleep quality may be effective in reducing the burden of pruritus and improving daily functioning and well-being in patients undergoing hemodialysis.

Preprint Statement

This manuscript has not been previously published and is not under consideration elsewhere. If the manuscript is posted on a preprint server, the authors will update it with a link to the final published version.

Statistical Compliance Statement

The statistics were checked prior to submission by an expert statistician, Ilhyun Lee, Email: [email protected].

导读:尿毒症性瘙痒是血液透析患者常见且痛苦的症状,常伴有疲劳和睡眠质量差。这些症状共同影响生活质量(QoL),但它们之间的相互关系尚不清楚。探讨疲劳和睡眠质量是否介导血液透析患者尿毒症性瘙痒与生活质量的关系。方法:采用定量中介分析进行横断面研究。来自韩国三家医院附属透析中心的175名血液透析患者完成了有效的自我报告测量,评估尿毒症瘙痒、疲劳、睡眠质量和生活质量。采用Baron和Kenny的框架、Sobel检验和自举法进行中介分析。结果:尿毒症瘙痒与疲劳有显著相关性(r = 0.30, p)。结论:尿毒症瘙痒通过影响疲劳和睡眠质量间接影响生活质量。这表明它的影响是通过相互关联的症状而不是直接起作用的。研究结果支持在透析护理中采用综合症状管理方法的必要性。针对疲劳和睡眠质量的干预措施可能有效地减轻瘙痒的负担,改善血液透析患者的日常功能和幸福感。预印本声明:这份手稿以前没有发表过,也没有在其他地方考虑。如果手稿发布在预印本服务器上,作者将更新它,并提供最终出版版本的链接。统计符合性声明:统计数据在提交前由统计专家李一铉(音译)检查,电子邮件:tarra@statedu.com。
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引用次数: 0
Practical Strategies for Prevention of Catheter-Related Bloodstream Infections (CRBSI) in United States Hemodialysis Facilities 预防导管相关血流感染(CRBSI)在美国血液透析设施的实用策略。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-29 DOI: 10.1111/hdi.70005
Leslie P. Wong

Hemodialysis (HD) patients are at high risk for infection owing to the necessity of vascular access to the bloodstream for treatments. Despite widespread efforts to promote early establishment of arteriovenous fistula or graft (AVF/G) for HD, 70%–80% of patients initiate dialysis with a central venous catheter (CVC). Catheter-related bloodstream infections (CRBSIs) are a known risk of central venous catheter use, accounting for 70% of HD access-related bloodstream infections. Given the significant morbidity, mortality, and cost associated with central venous catheter use, prevention of CRBSIs is a major priority for nephrologists, dialysis facilities, and kidney care organizations attempting to improve quality and deliver safe care to dialysis patients. Recent strategies for prevention of CRBSI in HD have broadened focus to pre-dialysis education and planning and a growing armamentarium of evidence-based interventions to avoid or mitigate the consequences of central venous catheter use. New commercially available products containing chlorhexidine and taurolidine promise to augment core interventions to prevent CRBSI in dialysis facilities. This manuscript reviews selected topics and recent advances in knowledge related to preventing CRBSI in HD, with emphasis on dialysis care in United States.

血液透析(HD)患者感染的风险很高,因为需要血管进入血液进行治疗。尽管人们普遍提倡早期建立动静脉瘘或移植物(AVF/G)治疗HD,但70%-80%的患者开始使用中心静脉导管(CVC)进行透析。导管相关血流感染(crbsi)是使用中心静脉导管的已知风险,占HD通路相关血流感染的70%。考虑到中心静脉导管使用相关的显著发病率、死亡率和成本,预防crbsi是肾病学家、透析机构和肾脏护理组织试图提高透析质量和为透析患者提供安全护理的首要任务。最近预防HD患者CRBSI的策略已扩大到透析前教育和计划,以及越来越多的循证干预措施,以避免或减轻中心静脉导管使用的后果。含有氯己定和牛罗列定的新市售产品有望增强核心干预措施,以预防透析设施中的CRBSI。这篇文章回顾了与预防HD患者CRBSI相关的选定主题和最新进展,重点是美国的透析护理。
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引用次数: 0
Use of Extracorporeal Therapies to Treat Severe Caffeine Poisoning 使用体外疗法治疗严重咖啡因中毒。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-24 DOI: 10.1111/hdi.70002
Saeko Kohara, Yoshito Kamijo, Michiko Takai, Ryoko Kyan, Eiju Hasegawa, Takuya Shimane

Introduction

Reflecting on recent reports suggesting the efficacy of extracorporeal blood purification, including hemodialysis, for severe caffeine poisoning, we conducted a retrospective 5-year follow-up study on acute caffeine poisoning in Japan particularly focusing on extracorporeal blood purification.

Methods

Patients transported to emergency facilities between April 2016 and March 2021 after consuming large or excessive amounts of over-the-counter drugs and energy drinks containing caffeine as a primary ingredient were included. We collected information on demographic characteristics, medical history, the caffeine-containing products consumed, clinical and laboratory findings, treatments, and outcomes using a questionnaire. We compared the data of patients who were treated with and without extracorporeal blood purification (blood purification vs. nonblood purification group). We also compared our findings with those of a previous related study.

Findings

Seventy-six patients were included. Patients in the blood purification group (n = 22) were significantly older (p = 0.02), ingested higher estimated doses of caffeine (p < 0.01), demonstrated higher pulse rates (p = 0.01), respiratory rates (p = 0.03), and serum glucose levels (p = 0.05) on admission, resulting in longer hospital stays (p < 0.01) than those in the nonblood purification group (n = 54). However, their backgrounds, clinical features on arrival, and clinical signs and symptoms during the clinical course were similar between this and the previous study. Compared to the previous study, this study had a higher percentage of patients who underwent extracorporeal blood purification (16.8% vs. 28.9%; p = 0.07), including hemodialysis (10.9% vs. 22.4%; p = 0.06); nevertheless, no statistically significant differences were observed in the prognoses between the studies.

Conclusions

Currently, the use of extracorporeal blood purification including hemodialysis for the treatment of caffeine poisoning is being promoted in Japan; however, the decision to administer it mostly depends on the patients' ingested doses or vital signs, and not on the serum caffeine levels. Further studies are warranted to confirm whether extracorporeal blood purification improves the prognoses of patients with severe caffeine poisoning.

引言:考虑到最近的报道表明体外血液净化(包括血液透析)对严重咖啡因中毒的疗效,我们在日本进行了一项为期6年的急性咖啡因中毒回顾性随访研究,特别关注体外血液净化。方法:纳入2016年4月至2022年3月期间因大量或过量服用非处方药和以咖啡因为主要成分的能量饮料而被送往急救机构的患者。我们通过问卷调查收集了人口统计学特征、病史、摄入的含咖啡因产品、临床和实验室结果、治疗和结果等信息。我们比较了接受和不接受体外血液净化治疗的患者的数据(血液净化组与非血液净化组)。我们还将我们的研究结果与之前的相关研究结果进行了比较。结果:纳入76例患者。血液净化组(n = 22)患者明显年龄较大(p = 0.02),摄入的咖啡因估计剂量较高(p)。结论:目前,日本正在推广使用体外血液净化包括血液透析治疗咖啡因中毒;然而,决定是否使用它主要取决于患者的摄入剂量或生命体征,而不是血清咖啡因水平。需要进一步的研究来证实体外血液净化是否能改善严重咖啡因中毒患者的预后。
{"title":"Use of Extracorporeal Therapies to Treat Severe Caffeine Poisoning","authors":"Saeko Kohara,&nbsp;Yoshito Kamijo,&nbsp;Michiko Takai,&nbsp;Ryoko Kyan,&nbsp;Eiju Hasegawa,&nbsp;Takuya Shimane","doi":"10.1111/hdi.70002","DOIUrl":"10.1111/hdi.70002","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Reflecting on recent reports suggesting the efficacy of extracorporeal blood purification, including hemodialysis, for severe caffeine poisoning, we conducted a retrospective 5-year follow-up study on acute caffeine poisoning in Japan particularly focusing on extracorporeal blood purification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients transported to emergency facilities between April 2016 and March 2021 after consuming large or excessive amounts of over-the-counter drugs and energy drinks containing caffeine as a primary ingredient were included. We collected information on demographic characteristics, medical history, the caffeine-containing products consumed, clinical and laboratory findings, treatments, and outcomes using a questionnaire. We compared the data of patients who were treated with and without extracorporeal blood purification (blood purification vs. nonblood purification group). We also compared our findings with those of a previous related study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>Seventy-six patients were included. Patients in the blood purification group (<i>n</i> = 22) were significantly older (<i>p</i> = 0.02), ingested higher estimated doses of caffeine (<i>p</i> &lt; 0.01), demonstrated higher pulse rates (<i>p</i> = 0.01), respiratory rates (<i>p</i> = 0.03), and serum glucose levels (<i>p</i> = 0.05) on admission, resulting in longer hospital stays (<i>p</i> &lt; 0.01) than those in the nonblood purification group (<i>n</i> = 54). However, their backgrounds, clinical features on arrival, and clinical signs and symptoms during the clinical course were similar between this and the previous study. Compared to the previous study, this study had a higher percentage of patients who underwent extracorporeal blood purification (16.8% vs. 28.9%; <i>p</i> = 0.07), including hemodialysis (10.9% vs. 22.4%; <i>p</i> = 0.06); nevertheless, no statistically significant differences were observed in the prognoses between the studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Currently, the use of extracorporeal blood purification including hemodialysis for the treatment of caffeine poisoning is being promoted in Japan; however, the decision to administer it mostly depends on the patients' ingested doses or vital signs, and not on the serum caffeine levels. Further studies are warranted to confirm whether extracorporeal blood purification improves the prognoses of patients with severe caffeine poisoning.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"30 1","pages":"73-79"},"PeriodicalIF":1.2,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/hdi.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Single Cannulaton Technique for Puncturing Arteriovenous Fistulas: Randomized Comparison With Rope Ladder Technique Cannulation 多重单管技术穿刺动静脉瘘:与绳梯技术插管的随机比较。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-17 DOI: 10.1111/hdi.70000
Fang Xu, Jun Qiu, Shanshan Huo, Haitao Bai, Xia Wang, Peng Shu

Objective

This study aims to evaluate the impact of multiple single cannulation technique (MuST) on complications associated with arteriovenous fistulas (AV fistulas) in hemodialysis patients.

Methods

Patients who initiated hemodialysis using AV fistulas at our hospital between August 2023 and December 2023 were selected using convenience sampling. Participants were randomly assigned to either the control group or the experimental group using a random number table, with odd-numbered patients placed in the control group and even-numbered patients in the experimental group. The experimental group received MuST, while the control group received the rope ladder cannulation technique. After 12 months of follow-up, we assessed the incidence of aneurysms, thrombosis, infiltration, and stenosis, along with the cannulation success rate. Pain levels were evaluated using the Visual Analogue Scale (VAS) for pain, and cannulation difficulty was rated using Likert's five-point scale.

Results

The experimental group exhibited significantly lower incidences of aneurysms (3.44% vs. 15.3%), thrombus (1.72% vs. 13.6%), and stenosis (1.72% vs. 11.7%) compared to the control group (p < 0.05). The cannulation success rate was also significantly higher in the experimental group (99.5% vs. 99.0%) (p < 0.05). Moreover, the experimental group reported significantly lower cannulation difficulty scores (1.41 ± 0.54 vs. 2.24 ± 1.04) and pain scores (1.82 ± 0.93 vs. 3.29 ± 0.77) (p < 0.05). However, the incidence of infiltration was significantly higher in the experimental group (19.0% vs. 6.78%).

Conclusions

MuST was associated with reduced pain and higher success rate of cannulation, and fewer complications compared to the standard rope ladder method. However, it was linked with a higher rate of infiltration. These findings suggest that MuST may be a promising alternative and warrants further investigation and broader clinical adoption.

目的:本研究旨在评价多次单管技术(MuST)对血液透析患者动静脉瘘(AV瘘)并发症的影响。方法:选取2023年8月至2023年12月在我院进行房室瘘血液透析的患者,采用方便抽样法。参与者使用随机数字表随机分配到对照组或实验组,奇数患者被安排在对照组,偶数患者被安排在实验组。实验组采用MuST,对照组采用绳梯插管技术。随访12个月后,我们评估动脉瘤、血栓、浸润和狭窄的发生率以及插管成功率。采用视觉模拟疼痛量表(Visual Analogue Scale, VAS)评估疼痛程度,采用Likert五分制评分插管难度。结果:实验组动脉瘤发生率(3.44%比15.3%)、血栓发生率(1.72%比13.6%)、狭窄发生率(1.72%比11.7%)明显低于对照组(p)。结论:与标准绳梯法相比,MuST能减轻疼痛、提高插管成功率、减少并发症。然而,它与较高的渗透率有关。这些发现表明,MuST可能是一个有希望的替代方案,值得进一步研究和更广泛的临床应用。
{"title":"Multiple Single Cannulaton Technique for Puncturing Arteriovenous Fistulas: Randomized Comparison With Rope Ladder Technique Cannulation","authors":"Fang Xu,&nbsp;Jun Qiu,&nbsp;Shanshan Huo,&nbsp;Haitao Bai,&nbsp;Xia Wang,&nbsp;Peng Shu","doi":"10.1111/hdi.70000","DOIUrl":"10.1111/hdi.70000","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aims to evaluate the impact of multiple single cannulation technique (MuST) on complications associated with arteriovenous fistulas (AV fistulas) in hemodialysis patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients who initiated hemodialysis using AV fistulas at our hospital between August 2023 and December 2023 were selected using convenience sampling. Participants were randomly assigned to either the control group or the experimental group using a random number table, with odd-numbered patients placed in the control group and even-numbered patients in the experimental group. The experimental group received MuST, while the control group received the rope ladder cannulation technique. After 12 months of follow-up, we assessed the incidence of aneurysms, thrombosis, infiltration, and stenosis, along with the cannulation success rate. Pain levels were evaluated using the Visual Analogue Scale (VAS) for pain, and cannulation difficulty was rated using Likert's five-point scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The experimental group exhibited significantly lower incidences of aneurysms (3.44% vs. 15.3%), thrombus (1.72% vs. 13.6%), and stenosis (1.72% vs. 11.7%) compared to the control group (<i>p</i> &lt; 0.05). The cannulation success rate was also significantly higher in the experimental group (99.5% vs. 99.0%) (<i>p</i> &lt; 0.05). Moreover, the experimental group reported significantly lower cannulation difficulty scores (1.41 ± 0.54 vs. 2.24 ± 1.04) and pain scores (1.82 ± 0.93 vs. 3.29 ± 0.77) (<i>p</i> &lt; 0.05). However, the incidence of infiltration was significantly higher in the experimental group (19.0% vs. 6.78%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>MuST was associated with reduced pain and higher success rate of cannulation, and fewer complications compared to the standard rope ladder method. However, it was linked with a higher rate of infiltration. These findings suggest that MuST may be a promising alternative and warrants further investigation and broader clinical adoption.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"30 1","pages":"58-65"},"PeriodicalIF":1.2,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three Dimensional Speckle Tracking Echocardiography in Hemodialysis Patients 三维斑点跟踪超声心动图在血液透析患者中的应用。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-16 DOI: 10.1111/hdi.13272
Serap Yadigar, Gülümser Sevgin Halil, Pınar Özdemir, Erman Özdemir, Ezgi Gültekin Güner, Abdurrahman Engin Demir, Sukru Hakan Gunduz, Banu Şahin Yıldız, Mustafa Yıldız

Background

It has been suggested that ventricular strain measurements may be impaired in chronic hemodialysis patients despite having no history of heart disease. The aim of this study is to investigate whether ventricular strain parameters can be used to detect subclinical cardiac dysfunction in hemodialysis patients.

Methods

In our study, 47 patients under the age of 65 years with no known history of cardiac or valvular disease and receiving chronic hemodialysis treatment for at least 1 year were compared with an age- and sex-matched control group of 29 healthy individuals. Transthoracic echocardiography was used to evaluate parameters such as global longitudinal strain, right ventricular global longitudinal strain, and left ventricular diastolic diameter. Differences between groups were analyzed by Student's t-test and Mann–Whitney U test.

Results

The global longitudinal strain values of the hemodialysis group were significantly lower than those of the control group (−13.2 ± 3.91 vs. −22.1 ± 1.59, p < 0.001). Right ventricular global longitudinal strain (RV GLS) and left ventricular diastolic diameter were also significantly impaired in the hemodialysis group (p < 0.05). These results indicate the presence of subclinical cardiac dysfunction in hemodialysis patients.

Conclusions

Ventricular strain measurements may be impaired in chronic hemodialysis patients without a history of cardiovascular disease. Therefore, it is considered that ventricular strain measurements can be a useful method for the early detection of cardiac dysfunction in hemodialysis patients.

背景:有研究表明,尽管没有心脏病史,但慢性血液透析患者的心室应变测量可能会受损。本研究的目的是探讨心室应变参数是否可以用于检测血液透析患者的亚临床心功能障碍。方法:在我们的研究中,47例65岁以下、无心脏或瓣膜疾病病史且接受慢性血液透析治疗至少1年的患者与29例年龄和性别匹配的健康对照组进行比较。经胸超声心动图评价总纵应变、右心室总纵应变、左心室舒张直径等参数。组间差异采用Student’st检验和Mann-Whitney U检验。结果:血液透析组的整体纵向应变值明显低于对照组(-13.2±3.91 vs -22.1±1.59,p)。结论:无心血管病史的慢性血液透析患者的心室应变测量可能受损。因此,心室应变测量可作为血液透析患者心功能障碍早期检测的有效方法。
{"title":"Three Dimensional Speckle Tracking Echocardiography in Hemodialysis Patients","authors":"Serap Yadigar,&nbsp;Gülümser Sevgin Halil,&nbsp;Pınar Özdemir,&nbsp;Erman Özdemir,&nbsp;Ezgi Gültekin Güner,&nbsp;Abdurrahman Engin Demir,&nbsp;Sukru Hakan Gunduz,&nbsp;Banu Şahin Yıldız,&nbsp;Mustafa Yıldız","doi":"10.1111/hdi.13272","DOIUrl":"10.1111/hdi.13272","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>It has been suggested that ventricular strain measurements may be impaired in chronic hemodialysis patients despite having no history of heart disease. The aim of this study is to investigate whether ventricular strain parameters can be used to detect subclinical cardiac dysfunction in hemodialysis patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In our study, 47 patients under the age of 65 years with no known history of cardiac or valvular disease and receiving chronic hemodialysis treatment for at least 1 year were compared with an age- and sex-matched control group of 29 healthy individuals. Transthoracic echocardiography was used to evaluate parameters such as global longitudinal strain, right ventricular global longitudinal strain, and left ventricular diastolic diameter. Differences between groups were analyzed by Student's <i>t</i>-test and Mann–Whitney <i>U</i> test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The global longitudinal strain values of the hemodialysis group were significantly lower than those of the control group (−13.2 ± 3.91 vs. −22.1 ± 1.59, <i>p</i> &lt; 0.001). Right ventricular global longitudinal strain (RV GLS) and left ventricular diastolic diameter were also significantly impaired in the hemodialysis group (<i>p</i> &lt; 0.05). These results indicate the presence of subclinical cardiac dysfunction in hemodialysis patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Ventricular strain measurements may be impaired in chronic hemodialysis patients without a history of cardiovascular disease. Therefore, it is considered that ventricular strain measurements can be a useful method for the early detection of cardiac dysfunction in hemodialysis patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 4","pages":"588-598"},"PeriodicalIF":1.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green Dialysis Review: Reducing Water, Energy, and Waste 绿色透析综述:减少水、能源和浪费。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-15 DOI: 10.1111/hdi.13251
Kyle J. Backston, Cole J. Thompson, Manya Raina, Nafees R. Sathik, Lydia S. Noh, Pooja P. Lokkur, Shyam B. Bansal

Background

Hemodialysis is a lifesaving therapy but imposes a significant environmental burden due to its excessive consumption of water and energy and the generation of non-recyclable medical waste. The emerging Green Dialysis movement aims to mitigate these environmental impacts by promoting sustainable practices in nephrology. We summarize current knowledge on the environmental challenges associated with hemodialysis and highlight innovative strategies for reducing its ecological footprint through the Green Dialysis framework.

Methods

This review synthesized recent literature on water use, energy consumption, and waste generation in dialysis, evaluating practical and technological innovations, including water recycling, reduced dialysate flow, renewable energy integration, and sorbent-based systems, that aim to improve sustainability in nephrology care.

Results

Key environmental challenges of hemodialysis include excessive water and energy consumption and substantial waste generation. Hemodialysis facilities consume vast quantities of water, with up to 60 percent of treated water being discarded, while energy demands produce considerable carbon emissions. Waste production, particularly plastic waste, poses additional environmental challenges, as much of it is non-recyclable and poorly managed. Through the Green Dialysis movement, there is a concerted effort to promote sustainable practices in nephrology. Innovative solutions such as water recycling, reduced dialysate flow rates, adoption of renewable energy sources, and advanced hemodialysis machine designs may minimize resource use and waste.

Conclusion

The Green Dialysis movement offers a comprehensive and actionable approach to improving the environmental sustainability of dialysis care. By integrating these strategies, the Green Dialysis movement aims to mitigate the environmental footprint of hemodialysis, fostering a sustainable and resilient future for nephrology care.

背景:血液透析是一种挽救生命的治疗方法,但由于其过度消耗水和能源以及产生不可回收的医疗废物,造成了重大的环境负担。新兴的绿色透析运动旨在通过促进肾病学的可持续实践来减轻这些环境影响。我们总结了与血液透析相关的环境挑战的当前知识,并强调了通过绿色透析框架减少其生态足迹的创新策略。方法:本综述综合了最近关于透析中的水使用、能源消耗和废物产生的文献,评估了实用和技术创新,包括水循环利用、减少透析液流量、可再生能源整合和基于吸附剂的系统,旨在提高肾病护理的可持续性。结果:血液透析的主要环境挑战包括过度的水和能源消耗以及大量的废物产生。血液透析设施消耗大量的水,高达60%的处理过的水被丢弃,而能源需求产生了可观的碳排放。废物生产,特别是塑料废物,带来了额外的环境挑战,因为其中大部分是不可回收的,管理不善。通过绿色透析运动,有一个协调一致的努力,以促进可持续的做法在肾脏病。创新的解决方案,如水循环利用、降低透析液流速、采用可再生能源和先进的血液透析机设计,可以最大限度地减少资源使用和浪费。结论:绿色透析运动为改善透析护理的环境可持续性提供了一种全面可行的方法。通过整合这些策略,绿色透析运动旨在减轻血液透析的环境足迹,促进肾病护理的可持续和有弹性的未来。
{"title":"Green Dialysis Review: Reducing Water, Energy, and Waste","authors":"Kyle J. Backston,&nbsp;Cole J. Thompson,&nbsp;Manya Raina,&nbsp;Nafees R. Sathik,&nbsp;Lydia S. Noh,&nbsp;Pooja P. Lokkur,&nbsp;Shyam B. Bansal","doi":"10.1111/hdi.13251","DOIUrl":"10.1111/hdi.13251","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hemodialysis is a lifesaving therapy but imposes a significant environmental burden due to its excessive consumption of water and energy and the generation of non-recyclable medical waste. The emerging Green Dialysis movement aims to mitigate these environmental impacts by promoting sustainable practices in nephrology. We summarize current knowledge on the environmental challenges associated with hemodialysis and highlight innovative strategies for reducing its ecological footprint through the Green Dialysis framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review synthesized recent literature on water use, energy consumption, and waste generation in dialysis, evaluating practical and technological innovations, including water recycling, reduced dialysate flow, renewable energy integration, and sorbent-based systems, that aim to improve sustainability in nephrology care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Key environmental challenges of hemodialysis include excessive water and energy consumption and substantial waste generation. Hemodialysis facilities consume vast quantities of water, with up to 60 percent of treated water being discarded, while energy demands produce considerable carbon emissions. Waste production, particularly plastic waste, poses additional environmental challenges, as much of it is non-recyclable and poorly managed. Through the Green Dialysis movement, there is a concerted effort to promote sustainable practices in nephrology. Innovative solutions such as water recycling, reduced dialysate flow rates, adoption of renewable energy sources, and advanced hemodialysis machine designs may minimize resource use and waste.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The Green Dialysis movement offers a comprehensive and actionable approach to improving the environmental sustainability of dialysis care. By integrating these strategies, the Green Dialysis movement aims to mitigate the environmental footprint of hemodialysis, fostering a sustainable and resilient future for nephrology care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 4","pages":"463-471"},"PeriodicalIF":1.2,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Hemorrhagic Rectal Ulcer in a Uremic Patient: A Case Report and Literature Review 尿毒症患者急性出血性直肠溃疡1例报告及文献复习。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-12 DOI: 10.1111/hdi.13273
Dongdong Liu, Xingbing Han, Min Li, Lingyan Li, Yi Huang, Jingmei Song

Background

Acute hemorrhagic rectal ulcer (AHU) is a rare but severe cause of painless lower GI bleeding, mainly in elderly patients with comorbidities. Uremia increases bleeding risk due to platelet dysfunction and hemodialysis anticoagulation, but AHU in dialysis patients is underreported.

Aims

To report a case of AHU in a uremic hemodialysis patient and analyze management challenges.

Materials and Methods

A 78-year-old female with ESRD presented with rectal bleeding. Colonoscopy showed a 3 × 4 cm ulcer, managed with clips, injections, and adhesives.

Results

The patient experienced recurrent bleeding, requiring multiple endoscopic interventions (titanium clip placement, methylene blue-polydocanol injection, tissue adhesive). Despite initial hemostasis, she developed worsening heart failure and multi-organ failure, dying at home after ICU admission.

Discussion

Uremia, anticoagulation, and comorbidities fueled bleeding. Endoscopic therapy was key, but systemic decline dominated. Multidisciplinary care is vital for high-risk patients.

Conclusion

This case instills awareness of the exigency regarding continuous observation and tailored management in this population of patients with high risk.

背景:急性出血性直肠溃疡(AHU)是一种罕见但严重的下消化道无痛性出血原因,主要发生在有合并症的老年患者中。尿毒症由于血小板功能障碍和血液透析抗凝而增加出血风险,但透析患者AHU的报道不足。目的:报告一例尿毒症血液透析患者的AHU并分析处理挑战。材料和方法:一位78岁的ESRD女性患者以直肠出血为主要表现。结肠镜检查显示一个3 × 4厘米的溃疡,用夹子、注射和粘接剂治疗。结果:患者反复出血,需要多次内镜干预(钛夹置入、亚甲基蓝-聚多酚注射、组织粘接剂)。尽管最初止血,但她出现了恶化的心力衰竭和多器官衰竭,在ICU入院后死于家中。讨论:尿毒症、抗凝和合并症引发出血。内镜治疗是关键,但全身性衰退占主导地位。多学科治疗对高危患者至关重要。结论:该病例使人们意识到对这类高危患者进行持续观察和针对性治疗的紧迫性。
{"title":"Acute Hemorrhagic Rectal Ulcer in a Uremic Patient: A Case Report and Literature Review","authors":"Dongdong Liu,&nbsp;Xingbing Han,&nbsp;Min Li,&nbsp;Lingyan Li,&nbsp;Yi Huang,&nbsp;Jingmei Song","doi":"10.1111/hdi.13273","DOIUrl":"10.1111/hdi.13273","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Acute hemorrhagic rectal ulcer (AHU) is a rare but severe cause of painless lower GI bleeding, mainly in elderly patients with comorbidities. Uremia increases bleeding risk due to platelet dysfunction and hemodialysis anticoagulation, but AHU in dialysis patients is underreported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To report a case of AHU in a uremic hemodialysis patient and analyze management challenges.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A 78-year-old female with ESRD presented with rectal bleeding. Colonoscopy showed a 3 × 4 cm ulcer, managed with clips, injections, and adhesives.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The patient experienced recurrent bleeding, requiring multiple endoscopic interventions (titanium clip placement, methylene blue-polydocanol injection, tissue adhesive). Despite initial hemostasis, she developed worsening heart failure and multi-organ failure, dying at home after ICU admission.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Uremia, anticoagulation, and comorbidities fueled bleeding. Endoscopic therapy was key, but systemic decline dominated. Multidisciplinary care is vital for high-risk patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case instills awareness of the exigency regarding continuous observation and tailored management in this population of patients with high risk.</p>\u0000 </section>\u0000 </div>","PeriodicalId":12815,"journal":{"name":"Hemodialysis International","volume":"29 4","pages":"730-736"},"PeriodicalIF":1.2,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Artificial Intelligence in Scientific Writing. The Danger of Trying Too Hard to Please 人工智能在科学写作中的应用。过分努力取悦他人的危险。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-12 DOI: 10.1111/hdi.13270
John T. Daugirdas

The author describes his experience using several artificial intelligence programs to assist in the process of editing or preparing manuscripts for publication. While the programs were very useful to increase clarity and optimize the English of previously written text, problems arose when asked to review the literature to describe or expand on concepts, and then to cite references to support those statements. Citations were sometimes fabricated. The artificial intelligence program would even provide PubMed identification (PMID) numbers for references cited, which sometimes pointed to completely different publications. In references that were correctly cited, a request to extract data from their abstracts yielded data that were completely fabricated or incorrect. The newer versions of these artificial intelligence programs appear to be enormously helpful in helping with the process of scientific writing, but one needs to assiduously verify every statement made with regard to their interpretation of the medical literature and double-check any citations by retrieving and reading those references. Because statements made by these agents are proffered with great confidence and using excellent writing skills, the resulting errors can be difficult to anticipate. The motivations behind such errors are unknown, but appear to be related to a desire of AI to please the user at any cost. Programmers who create these tools somehow managed to allow such errors, and this issue must be addressed in future versions of AI. Also, it would help greatly if AI had access to the full text of medical scientific articles, which might be achieved by contractual agreements with the main medical publishers.

作者描述了他使用几个人工智能程序来协助编辑或准备出版手稿的经验。虽然这些程序对于提高先前书面文本的清晰度和优化英语非常有用,但当被要求回顾文献以描述或扩展概念,然后引用参考文献来支持这些陈述时,问题就出现了。引文有时是捏造的。人工智能程序甚至会为引用的参考文献提供PubMed识别(PMID)号码,有时会指向完全不同的出版物。在正确引用的参考文献中,从其摘要中提取数据的请求会产生完全捏造或不正确的数据。这些新版本的人工智能程序似乎在帮助科学写作的过程中有很大的帮助,但人们需要认真核实每一个关于它们对医学文献的解释的陈述,并通过检索和阅读这些参考文献来仔细检查任何引用。由于这些代理人的陈述充满信心,并且使用了出色的写作技巧,因此产生的错误很难预测。这些错误背后的动机尚不清楚,但似乎与人工智能不惜一切代价取悦用户的愿望有关。创造这些工具的程序员设法允许这样的错误,这个问题必须在未来的AI版本中解决。此外,如果人工智能能够获得医学科学文章的全文,这将大有帮助,这可以通过与主要医学出版商达成合同协议来实现。
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引用次数: 0
Psychological Distress in Hemodialysis: Impact of Life Events, Illness Perception, and Difficulty Processing Emotions (Alexithymia) 血液透析中的心理困扰:生活事件、疾病感知和情绪处理困难(述情障碍)的影响。
IF 1.2 4区 医学 Q3 UROLOGY & NEPHROLOGY Pub Date : 2025-06-10 DOI: 10.1111/hdi.13269
Weihuan Sun, Yanshuang Chang

Background

Depression and anxiety in individuals undergoing hemodialysis (HD) significantly impair daily functioning and hinder renal rehabilitation efforts. Various factors, including negative life events, illness perceptions, and difficulty processing emotions (alexithymia), have been associated with these psychological challenges; however, their specific impact on HD-related psychological distress remains unclear.

Methods

In this cross-sectional study, 246 individuals receiving HD were assessed using self-administered questionnaires, including the Life Events Scale (LES), Illness Perceptions Questionnaire (IPQ-R), Toronto Alexithymia Scale (TAS-20), and the Hospital Anxiety and Depression Scale (HADS).

Results

The study found that 32.5% and 41.5% of HD patients exhibited symptoms of depression and anxiety, respectively. Logistic regression analyses revealed significant correlations between negative life events, illness perceptions, and alexithymia with both depression and anxiety. Specifically, higher scores on the “Negative Emotional Representation about Illness” subscale were associated with an increased risk of depression (adjusted odds ratio [OR], 1.302; 95% confidence interval [CI], 1.118–1.544; p < 0.001). Conversely, lower scores on “Personal Control” were linked to a heightened risk of depression (adjusted OR, 0.796; 95% CI, 0.683–0.927; p = 0.003). For anxiety, elevated scores in “Negative Emotional Representation about Illness” (adjusted OR, 1.185; 95% CI, 1.014–1.261; p = 0.015) and “difficulty identifying feelings” (adjusted OR, 1.210; 95% CI, 1.031–1.411; p = 0.016) indicated increased risk, while lower scores in “Personal Control” were similarly associated with heightened anxiety risk (adjusted OR, 0.852; 95% CI, 0.734–0.983; p = 0.042).

Conclusion

This study suggests that negative life events, specific illness perceptions, and alexithymia are significant predictors of depression and anxiety among HD patients. Addressing maladaptive illness perceptions and emotional regulation deficits could offer novel strategies to enhance mental health outcomes in this population, highlighting the need for further investigation.

背景:接受血液透析(HD)的个体的抑郁和焦虑显著损害日常功能并阻碍肾脏康复。各种因素,包括消极的生活事件、疾病感知和处理情绪困难(述情障碍),都与这些心理挑战有关;然而,它们对hd相关心理困扰的具体影响尚不清楚。方法:采用生活事件量表(LES)、疾病感知量表(IPQ-R)、多伦多述情障碍量表(TAS-20)和医院焦虑抑郁量表(HADS)等自填问卷对246例HD患者进行评估。结果:研究发现,32.5%和41.5%的HD患者分别表现出抑郁和焦虑症状。逻辑回归分析显示负面生活事件、疾病认知和述情障碍与抑郁和焦虑之间存在显著相关性。具体而言,“疾病负面情绪表征”分量表得分越高,患抑郁症的风险越高(调整优势比[OR], 1.302;95%置信区间[CI], 1.118-1.544;结论:本研究提示负性生活事件、特定疾病认知和述情障碍是HD患者抑郁和焦虑的重要预测因素。解决适应不良的疾病认知和情绪调节缺陷可能为提高这一人群的心理健康结果提供新的策略,强调了进一步研究的必要性。
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引用次数: 0
期刊
Hemodialysis International
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