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OX40 gene expression level on pathology sections obtained from Pituitary Adenomas tissues OX40基因在垂体腺瘤病理切片上的表达水平
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.99076
Buruç Erkan
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引用次数: 0
Comparison of SWE (Shear Wave Elastography) values with ADC (Apparent Diffusion Coefficient) values in the evaluation of breast lesions SWE(剪切波弹性成像)值与ADC(表观扩散系数)值在乳腺病变评估中的比较
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.56514
Ezgi Kartal Aygörmez
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引用次数: 0
Is There A Correlation Between Testicular Torsion in Children and the Climate Factors? 儿童睾丸扭转与气候因素有关吗?
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.79926
C. Şahin
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引用次数: 0
Why do parents choose to attend the emergency department? A Cross-sectional study 为什么家长选择到急诊科就诊?横断面研究
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.82642
Nevin Cambaz Kurt
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引用次数: 0
Intestinal spirochaetosis in an immunocompetent host: case report and review of literature 免疫正常宿主的肠螺旋体病:病例报告和文献回顾
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.87059
Ayse Ozbek
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引用次数: 0
Does epidural magnesium sulphate cause medulla spinalis injury in rabbits? 硬膜外硫酸镁会引起家兔脊髓损伤吗?
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.44365
Elvan Oçmen
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引用次数: 0
Assessment Of Thyroid Function in Patients with Parkinson's Disease 帕金森病患者甲状腺功能的评估
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.68889
Tamer Bayram
Introduction: The study aims to observe thyroid dysfunction, its prevalence, and the relationship between the Unified Parkinson’s Disease Rating Scale (UPDRS) and thyroid function in Parkinson’s patients. Methods: Seventy patients with Parkinson’s disease (PD) and 60 age-and sex-matched controls were enrolled in the study. PD patients were divided into tremor dominant-type (TDT) and akinetic-rigid-type (ART) subgroups. Serum fT4, TSH, and Anti TPO levels of patients were retrospectively reviewed. The results of the patients were compared with the controls, and the relationship between the UPDRS score and thyroid hormone levels was observed. Results: The mean levels of TSH and fT4 were higher in PD patients, but the difference was not statistically significant. TDT and ART subgroups did not show differences in age, UPDRS motor score, and TSH level. Only 1 (1.42%) female patient had hypothyroidism in the TDT subgroup. Three females and 2 males had subclinical hyperthyroidism in the PD group (2 females and 2 males in TDT and 1 female in the ART subgroup). The fT4 level and subclinical hyperthyroidism were significantly higher in the TDT subgroup than in ART. None of the patients in the PD group had hyperthyroidism or subclinical hypothyroidism. The prevalence of subclinical hyperthyroidism was higher in the PD group and the prevalence of hypothyroidism did not differ between the two groups. There was no significant relationship between the UPDRS score and thyroid hormone levels or anti-TPO. Discussion and Conclusion: Thyroid dysfunction in Parkinson’s patients may cause difficulties in the treatment and follow-up process, as thyroid hormone levels may aggravate or camouflage Parkinson’s symptoms. In the study, the frequency of subclinical hyperthyroidism was higher in PD patients. The mean fT4 level and subclinical hyperthyroidism in TDT were significantly higher than those with ART. In addition, there was no correlation between the severity of the disease and the thyroid results. Thyroid tests should be carefully evaluated to facilitate treatment regulation in Parkinson’s disease.
简介:本研究旨在观察帕金森病患者甲状腺功能障碍、患病率以及统一帕金森病评定量表(UPDRS)与甲状腺功能的关系。方法:70例帕金森病(PD)患者和60例年龄和性别匹配的对照组纳入研究。PD患者分为震颤优势型(TDT)亚组和动硬型(ART)亚组。回顾性分析患者血清fT4、TSH和抗TPO水平。将患者的结果与对照组进行比较,观察UPDRS评分与甲状腺激素水平的关系。结果:PD患者TSH、fT4平均水平较高,但差异无统计学意义。TDT和ART亚组在年龄、UPDRS运动评分和TSH水平上无差异。TDT亚组中仅有1例(1.42%)女性患者出现甲状腺功能减退。PD组出现亚临床甲状腺功能亢进3名女性,2名男性(TDT组2名女性,2名男性,ART组1名女性)。TDT组fT4水平和亚临床甲状腺功能亢进明显高于ART组。PD组无甲亢或亚临床甲状腺功能减退。PD组亚临床甲状腺功能亢进的患病率更高,两组之间甲状腺功能减退的患病率没有差异。UPDRS评分与甲状腺激素水平或抗tpo无显著相关性。讨论与结论:帕金森患者甲状腺功能障碍可能会加重或掩盖帕金森症状,给治疗和随访带来困难。在本研究中,PD患者出现亚临床甲状腺功能亢进的频率更高。TDT组fT4平均水平和亚临床甲状腺功能亢进明显高于ART组。此外,疾病的严重程度与甲状腺检查结果之间没有相关性。甲状腺检查应仔细评估,以促进帕金森病的治疗调节。
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引用次数: 0
Is lobectomy an appropriate surgical strategy for nodular goiter in endemic areas? 在流行地区,肺叶切除术是治疗结节性甲状腺肿的合适手术策略吗?
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.83584
Nurdan Altan
Introduction: Thyroid nodules are evaluated by fine-needle aspiration biopsy (FNAB) according to their radiologic characteristics. International guidelines recommend lobectomy according to the size of the nodules and FNAB results. The aim of this study is to assess whether lobectomy is one of the treatment choices in endemic areas. Methods: Patients who underwent lobectomy between January 2013 and September 2017 were studied retrospectively. Patients’ demographic features, thyroid hormone levels, medications, FNAB results before the surgery, lobectomy indications, ultrasonographic features, final pathologies, and secondary surgical interventions were recorded. Results: Data of 388 patients who underwent lobectomy were examined. As patients were classified according to their FNAB results, all categories had higher malignancy rates than expected in the final pathology results. One hundred and eighteen (30.4%) patients had undergone completion thyroidectomy. The final pathology of the completion thyroidectomy samples showed 24.07% (n=26) malignancy. Discussion and Conclusion: FNAB is the gold standard for the malignancy risks in thyroid nodules in all guidelines. In endemic areas, this classification system may be inadequate. Two-staged thyroid surgery is becoming more popular. In our series, 30.4% of patients had undergone completion thyroidectomy according to their final pathology results. We need to add newer sights to guidelines for endemic areas.
简介:甲状腺结节是根据其放射学特征通过细针穿刺活检(FNAB)评估的。国际指南建议根据结节的大小和FNAB结果进行肺叶切除术。本研究的目的是评估肺叶切除术是否为流行地区的治疗选择之一。方法:回顾性分析2013年1月至2017年9月接受肺叶切除术的患者。记录患者的人口统计学特征、甲状腺激素水平、用药情况、术前FNAB结果、肺叶切除指征、超声特征、最终病理及二次手术干预。结果:对388例肺叶切除术患者的资料进行了分析。根据FNAB结果对患者进行分类,在最终病理结果中,所有类别的恶性肿瘤发生率均高于预期。118例(30.4%)患者行完全性甲状腺切除术。完成甲状腺切除术样本的最终病理显示24.07% (n=26)为恶性肿瘤。讨论与结论:FNAB是所有指南中判断甲状腺结节恶性风险的金标准。在流行地区,这种分类系统可能不够。两阶段甲状腺手术正变得越来越流行。在我们的研究中,根据最终病理结果,30.4%的患者接受了完全甲状腺切除术。我们需要在流行地区的指南中增加更新的内容。
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引用次数: 0
Trifocal Nummular Headache; A case report of dramatical response to local anesthetic injection 三灶性麻状头痛;局部麻药注射产生显著反应1例报告
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2023.15975
Cansu Köseoğlu Toksoy
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引用次数: 0
The Role of Increase of Total IgE and Passive Smoking in Adenoid Vegetation Recurrences 总IgE升高与被动吸烟在腺样体肥大复发中的作用
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2018.57855
Selçuk Yıldız
Correspondence (İletişim): Selçuk Yıldız, M.D. Haydarpasa Numune Egitim ve Arastirma Hastanesi, Kulak Burun Bogaz Klinigi, Istanbul, Turkey Phone (Telefon): +90 216 542 32 32 E-mail (E-posta): selcukyildiz60@hotmail.com Submitted Date (Başvuru Tarihi): 05.03.2018 Accepted Date (Kabul Tarihi): 27.06.2018 Copyright 2019 Haydarpaşa Numune Medical Journal OPEN ACCESS This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/). 225 Yıldız et al., The Role of Allergy in Recurrence of Adenoid Vegetation / doi: 10.14744/hnhj.2018.57855 Studies advocate that AV is related to the presence of atopy in the patient. Coexistence between allergic rhinitis and AV has been reported to be significant. Also, some studies have suggested a significant relationship between increased IgE levels and adenotonsillar hypertrophy [2–12]. Smoking by parents leads to ciliary dysfunction in children and thus increases the incidence of upper respiratory tract infections, such as chronic sinusitis and chronic otitis media. Repetition of such infections may pave the way for the formation of adenoid hypertrophy by lymphoid tissue stimulation [13–17]. Allergy and passive smoking may have a role in patients who had undergone adenoidectomy and developed recurrent adenoid hypertrophy. In this study, based on this information in the literature, AV recurrence was screened in long-term control of children who had undergone adenoidectomy, and it was planned to investigate the role of atopy and exposure to cigarette smoke in recurrent cases. Materials and Methods The patients aged 4-17 years with total IgE values above 200 IU/L who had undergone adenoidectomy operation in our clinic at least 6-16 months ago between 2010 and 2014 were included in this study after approval of the Clinical Research Ethics Committee of Haydarpaşa Numune Training and Research Hospital was obtained. Patients who had undergone additional surgical procedures other than adenoidectomies, such as ventilation tube application or tonsillectomy, were not included in the study group. Files of only 30 patients who had undergone adenoidectomy were retrospectively reviewed. Identity information, anamnesis, body mass indexes, date of operation, physical examination findings and laboratory tests recorded during the application were noted on the case report forms. Anamnesis records were examined for nasal obstruction, history of frequent upper respiratory tract infections, open mouth sleep, mouth snoring and apnea, and also upper airway complaints were investigated. The findings were noted by questioning whether the patient himself/ herself smoked in the adolescent age group and whether or not his/her family was a smoker in all age groups. Among laboratory findings, total IgE values were recorded using RAST® test, and cases with higher than normal values were determined. Patients underwent a detailed ear nose throat and systemic examination at least six months postoperatively. Phy
通讯(İletişim): seluk Yıldız, M.D. Haydarpasa Numune Egitim ve Arastirma Hastanesi, Kulak Burun Bogaz Klinigi,土耳其伊斯坦布尔电话(Telefon): +90 216 542 32 32电子邮件(E-posta): selcukyildiz60@hotmail.com提交日期(bavuru Tarihi): 05.03.2018接受日期(喀布尔Tarihi): 27.06.2018版权所有2019 haydarpanumune Medical Journal OPEN ACCESS这是一篇在CC BY-NC许可(http://creativecommons.org/licenses/by-nc/4.0/)下的开放获取文章。225 Yıldız等,The Role of Allergy in The Recurrence of Adenoid Vegetation / doi: 10.14744/hnhj.2018.57855研究认为AV与患者的特应性存在有关。据报道,变应性鼻炎与AV的共存是显著的。此外,一些研究表明IgE水平升高与腺扁桃体肥大之间存在显著关系[2-12]。父母吸烟导致儿童纤毛功能障碍,从而增加上呼吸道感染的发病率,如慢性鼻窦炎和慢性中耳炎。这种感染的重复可能为淋巴组织刺激形成腺样体肥大铺平道路[13-17]。过敏和被动吸烟可能在接受腺样体切除术并复发性腺样体肥大的患者中起作用。本研究在文献资料的基础上,对腺样体切除术后的儿童进行了AV复发的长期对照筛查,并计划探讨特应性和吸烟暴露在复发病例中的作用。材料与方法2010年至2014年6-16个月前在我院行腺样体切除术的患者,年龄4-17岁,总IgE值大于200 IU/L,经海达医学培训与研究医院临床研究伦理委员会批准纳入本研究。除腺样体切除术外,接受过其他外科手术的患者,如通气管应用或扁桃体切除术,不包括在研究组中。回顾性分析了30例腺样体切除术患者的资料。在病例报告表格上注明了申请期间记录的身份信息、记忆、体重指数、手术日期、体检结果和实验室检查结果。检查鼻塞、频繁上呼吸道感染、张口睡眠、口部打鼾和呼吸暂停的记忆记录,并调查上呼吸道主诉。通过询问患者本人是否在青少年年龄段吸烟,以及他/她的家人是否在所有年龄段都吸烟,研究结果得到了注意。在实验室检查中,使用RAST®检测记录总IgE值,并确定高于正常值的病例。患者术后至少6个月接受详细的耳鼻喉和全身检查。体检还调查了过敏性鼻炎的存在。经鼻咽内镜检查确定后鼻孔梗阻程度。根据梗阻程度将后肛管梗阻分级如下:1级。0 - 25%;2级。2650%;三年级。51 - 75%;四年级。76 - 100%阻塞。非1级病例为AV复发。经过详细的询问和详细的体格检查,确定症状复发的病例。LLC Kaysville。犹他州。采用美国)进行统计分析。采用独立样本检验对研究数据进行评价。采用Yates连续性校正和Fisher精确检验比较定性数据。结果采用95%置信区间和p<0.05显著性水平进行评价。
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Haydarpasa Numune Training and Research Hospital Medical Journal
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