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Use of hemogram parameters in the differentiation of benign thyroid nodules and thyroid papillary carcinoma cases 血流图参数在甲状腺良性结节与甲状腺乳头状癌鉴别中的应用
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.97658
D. Ozdemir
Introduction: We aimed to compare red cell distribution width (RDW), mean platelet volume (MPV), and some other laboratory parameters in patients with papillary thyroid carcinoma (PTC) or benign thyroid nodule (BTN). Methods: A total of 365 cases (186 with PTC and 179 with BTN) who underwent lobectomy or bilateral total thyroidectomy were included in the study. The patients were divided into two groups, PTC and BTN, according to histopathological diagnosis. Results: 76.4% of the patients were female and the mean age was 54.94±13.76 years. The median RDW value was 13.3% (12.7–13.9) in the PTC group and 13.2% (12.7–14.2%) in the BTN group. Mean MPV value was 10.28±1.20 fL in the PTC group and 10.26±1.07 fL in the BTN group. The groups were similar in terms of MPV and RDW values (p=0.477 and p=0.883, respectively). Thyroid gland size and detected nodule sizes were significantly greater in the BTN group compared to the PTC group (p<0.001 for all). Discussion and Conclusion: Complete blood count results, including RDW and MPV, were found to have no clinical value in distinguishing between PTC and BTN
我们的目的是比较甲状腺乳头状癌(PTC)和良性甲状腺结节(BTN)患者的红细胞分布宽度(RDW)、平均血小板体积(MPV)和其他一些实验室参数。方法:对行双侧或双侧甲状腺全切除术的365例患者(PTC 186例,BTN 179例)进行回顾性分析。根据组织病理诊断将患者分为PTC组和BTN组。结果:女性占76.4%,平均年龄54.94±13.76岁。PTC组的中位RDW值为13.3% (12.7-13.9),BTN组为13.2%(12.7-14.2%)。PTC组MPV均值为10.28±1.20 fL, BTN组MPV均值为10.26±1.07 fL。两组在MPV和RDW值方面相似(p=0.477和p=0.883)。与PTC组相比,BTN组的甲状腺大小和检测到的结节大小显著大于PTC组(p<0.001)。讨论与结论:包括RDW和MPV在内的全血细胞计数结果在区分PTC和BTN方面没有临床价值
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引用次数: 0
Surgical Outcomes of Intracranial Meningiomas: A Retrospective Study 颅内脑膜瘤的手术效果:回顾性研究
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.11129
Eylem Burcu Kahraman Özlü
Introduction: In this study, it was aimed to evaluate the clinical outcomes of patients who underwent surgical resection for meningioma. Methods: Medical records were retrospectively reviewed for all cranial and spinal cases diagnosed and underwent surgery at BRSHH Hospital between 2012 and 2016. All intracranial meningioma patients constituted the core sample for this study. Results: This series included 136 (88 females, 48 males) patients, with a mean age of 55.1±14.1 years. The mean preoperative course was 23.0±40.5 months. The most common symptom was headache (71.3%). The most common location was the frontal region which was seen in 29 patients (21.3%). The mean follow-up period was 36.0±18.95 months. 84.4% of grade I, and 68.2% of grade II demonstrated isointense lesions on T1-weighted magnetic resonance imaging (MRIs) (p=0.027). 15.5% of grade I and 47.7% of grade II showed irregularity (p=0.04). Giant tumors were more commonly associated with non-grade I meningiomas than grade I (p=0.006). 58.9% of grade I and 79.5% of grade II meningiomas demonstrated peritumoral edema on MRIs. The presence of preoperative neurological deficit (p<0.0001), irregularity on MRI (p=0.002), and recurrence (p=0.002) were associated with poor prognosis of surgical outcomes. Gross-total resection (GTR) (p=0.0003) was associated with a good prognosis. Discussion and Conclusion: The presence of preoperative neurological deficit, irregularity on MRI, and recurrence were factors associated with poor prognosis of surgical outcomes. GTR was associated with good surgical outcomes. The presence of preoperative deficits and irregularity on MRIs were associated with a high recurrence rate.
在这项研究中,旨在评估脑膜瘤手术切除患者的临床结果。方法:回顾性分析2012年至2016年在BRSHH医院诊断并接受手术的所有颅脑和脊柱病例的病历。所有颅内脑膜瘤患者构成本研究的核心样本。结果:136例患者(女性88例,男性48例),平均年龄55.1±14.1岁。术前平均时间23.0±40.5个月。最常见的症状是头痛(71.3%)。最常见的部位是额叶区,29例(21.3%)。平均随访时间36.0±18.95个月。84.4%的I级和68.2%的II级患者在t1加权磁共振成像(mri)上表现为等强度病变(p=0.027)。15.5%的I级患者和47.7%的II级患者出现异常(p=0.04)。巨型肿瘤与非一级脑膜瘤的相关性高于一级脑膜瘤(p=0.006)。在mri上,58.9%的I级脑膜瘤和79.5%的II级脑膜瘤表现为瘤周水肿。术前神经功能缺损(p<0.0001)、MRI异常(p=0.002)和复发(p=0.002)与手术预后不良相关。总切除(GTR) (p=0.0003)与良好的预后相关。讨论与结论:术前神经功能缺损、MRI异常、复发是导致手术预后不良的因素。GTR与良好的手术结果相关。术前mri显示的缺陷和不规则与高复发率相关。
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引用次数: 0
Bloody nipple discharge in children: Single center experience 儿童乳头溢血:单中心经验
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.25986
Sefa Sağ
Introduction: Bloody nipple discharge (BND) in children is an exceptionally rare entity. The aim of the study was to evaluate the underlying etiologies, treatment strategies, and clinical outcomes in children with BND. Methods: The retrospective study included pediatric patients (aged below 18 years) who presented with BND in our clinic between May 2015 and May 2020. Demographic and clinical characteristics including age, gender, laboratory, ultrasound (US), and histopathological findings, treatment modalities, and follow-up records were evaluated for each patient. Results: Patients comprised six (75%) girls and two (25%) boys. Median age at diagnosis was 15 years (minimum-maximum: 3–192 months) and all the girls were adolescents. BND was located in the left breast in five and in the right in three patients, and bilateral BND was not detected in any patient. All patients had normal serum hormone levels and a negative discharge culture. In US examination, mammary ductal ectasia (MDE) was diagnosed in two patients, one patient had hypoechoic tissue in the subareolar region, whereas the others had normal US findings. Cytology showed ductal epithelial cells without malignancy, which confirmed MDE in all patients. BND resolved with antibiotic treatment in one patient and resolved with no treatment in other patients. Discussion and Conclusion: BND can occur in adolescent girls as well. MDE is a leading cause of BND. Given that MDE is usually a self-limiting condition, unnecessary invasive interventions should be avoided. Cytological and US examinations seem to be highly useful in the diagnosis and follow-up of patients with BND.
儿童乳头溢血(BND)是一种非常罕见的疾病。本研究的目的是评估BND患儿的潜在病因、治疗策略和临床结果。方法:回顾性研究纳入2015年5月至2020年5月期间在我院就诊的BND儿科患者(年龄在18岁以下)。评估每位患者的人口统计学和临床特征,包括年龄、性别、实验室、超声(US)、组织病理学结果、治疗方式和随访记录。结果:6例(75%)女孩,2例(25%)男孩。诊断时的中位年龄为15岁(最小-最大:3-192个月),所有女孩均为青少年。5例BND位于左乳,3例位于右乳,未发现双侧BND。所有患者血清激素水平正常,分泌物培养阴性。在超声检查中,两名患者被诊断为乳腺导管扩张(MDE),一名患者在乳晕下区有低回声组织,而其他患者的超声检查结果正常。细胞学检查显示导管上皮细胞无恶性肿瘤,证实所有患者均为MDE。1例患者抗生素治疗后BND消失,其余患者未治疗。讨论与结论:BND也可能发生在青春期的女孩身上。MDE是导致BND的主要原因。鉴于MDE通常是一种自限性疾病,应避免不必要的侵入性干预。细胞学和超声检查似乎对BND患者的诊断和随访非常有用。
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引用次数: 0
Supraclavicular Brachiocephalic Vein Access for Tunneled Dialysis Catheter Placement in Patients with Bilateral Internal Jugular Vein Thrombosis 双侧颈内静脉血栓形成患者的锁骨上头臂静脉隧道透析置管通路
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.09825
U. Öğüşlü
Introduction: To evaluate the safety, effectiveness, and outcomes of tunneled dialysis catheters (TDC) placed through supr-aclavicular brachiocephalic vein (BCV) access in patients with bilateral internal jugular vein (IJV) thrombosis. Methods: Between January 2017 and October 2020, TDCs were placed through supraclavicular BCV access in 46 patients with bilateral IJV thrombosis. Patient demographics, number of attempts, technical and clinical success rates, complications, and patency rates were noted. Results: 21 (45.7%) patients were male. The mean age was 65.9 years (range 20–89). All catheters were placed at the first attempt. The right BCV was accessed in 16 (34%) patients. The technical and clinical success rate was 100%. No major complication was encountered. The mean follow-up period was 573.5 (range 50–1698) days. 44/46 (95.7%) of the catheters were functional at 30 days. The infection rate was 2.7/1000 catheter days. 38 catheter exchanges (mean: 1.9, range: 1–6) were required in 20 patients. The primary and secondary patency rates were 77.8% and 95.2% at 6 months, 77.8% and 95.2% at 12 months, and 74.8% and 84.8% at 24 months, respectively. Discussion and Conclusion: TDC placement through supraclavicular BCV access is a viable option in patients with bilateral IJV thrombosis. High success rates and low complication rates with acceptable outcomes make this route an attractive alternative before proceeding to more complex access routes.
目的:评价通过锁骨上头臂静脉(BCV)通道置入隧道式透析导管(TDC)治疗双侧颈内静脉(IJV)血栓形成患者的安全性、有效性和结果。方法:2017年1月至2020年10月,46例双侧IJV血栓患者通过锁骨上BCV通道放置tdc。记录了患者人口统计、尝试次数、技术和临床成功率、并发症和通畅率。结果:男性21例(45.7%)。平均年龄65.9岁(20 ~ 89岁)。所有导尿管都是在第一次尝试时放置的。16例(34%)患者进入了正确的BCV。技术及临床成功率均为100%。没有遇到重大并发症。平均随访时间573.5天(50 ~ 1698天)。在30 d时,44/46(95.7%)的导管功能正常。感染率为2.7/1000导尿管d。20例患者需要38例导管交换(平均1.9例,范围1-6例)。6个月时原发性和继发性通畅率分别为77.8%和95.2%,12个月时77.8%和95.2%,24个月时74.8%和84.8%。讨论与结论:通过锁骨上BCV通道放置TDC是双侧IJV血栓形成患者的可行选择。高成功率和低并发症发生率以及可接受的结果使该路径在进行更复杂的访问路径之前成为一种有吸引力的选择。
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引用次数: 0
Ethics Committee Application Procedures in Clinical Trials 伦理委员会临床试验申请程序
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.56667
Hilal Ilbars
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引用次数: 0
Comprasion of The Results of Plication and Resection Techniques in Horizontal Strabismus Surgery 水平斜视手术中应用和切除技术效果的比较
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.54926
Gizem Yel
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引用次数: 0
The first case of Pediatric Multisystem Inflammatory Syndrome (MIS-C) to be diagnosed in our clinic in the late stages of the pandemic 小儿多系统炎症综合征(MIS-C)在大流行晚期在我们诊所确诊的第一例
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2021.76148
Elif Küçük
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引用次数: 0
Cerebral Oxygen Desaturation And Postoperative Cognitive Effects In Elderly Patients Operated In Beach Chair Position 老年患者采用沙滩椅位手术后脑氧饱和度及术后认知功能的影响
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.70446
A. Ozgultekin
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引用次数: 0
The evaluation of Sleep Hygiene in Subacromial Impingement Syndrome: A case control study 肩峰下撞击综合征患者睡眠卫生评价:一项病例对照研究
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.49091
Sibel Süzen Özbayrak
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引用次数: 0
Maturity-Onset Diabetes of the Young-2(MODY2) 青壮年型糖尿病(MODY2)
Pub Date : 2023-01-01 DOI: 10.14744/hnhj.2022.88886
Ayşe Gümüş Özçelik
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引用次数: 0
期刊
Haydarpasa Numune Training and Research Hospital Medical Journal
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