Pub Date : 2025-08-01Epub Date: 2025-07-23DOI: 10.21037/hbsn-2025-294
Jeong-Ju Yoo, Young Seok Kim, Sang Gyune Kim
{"title":"Listening to the spleen: a 100 Hz pulse toward a non-invasive way in assessing portal hypertension.","authors":"Jeong-Ju Yoo, Young Seok Kim, Sang Gyune Kim","doi":"10.21037/hbsn-2025-294","DOIUrl":"10.21037/hbsn-2025-294","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"658-661"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-25DOI: 10.21037/hbsn-2025-504
Bo Zhou, Minghao Sun, Mian Yang, Wei Cui, Huayu Yang
{"title":"Construction and application of multicellular tumor microenvironment models based on three-dimensional bioprinting technology.","authors":"Bo Zhou, Minghao Sun, Mian Yang, Wei Cui, Huayu Yang","doi":"10.21037/hbsn-2025-504","DOIUrl":"10.21037/hbsn-2025-504","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"692-696"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-21DOI: 10.21037/hbsn-2025-503
Liwei Du, Hongyuan Yi, Youkang Chen, Haifeng Xu
{"title":"Can portable artificial livers become an alternative to liver transplantation in the future?","authors":"Liwei Du, Hongyuan Yi, Youkang Chen, Haifeng Xu","doi":"10.21037/hbsn-2025-503","DOIUrl":"10.21037/hbsn-2025-503","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"669-672"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-25DOI: 10.21037/hbsn-2025-316
Alexander Olkus, Michael T Dill
{"title":"Beyond chemotherapy in biliary tract cancer: a closer look at the updated long-term follow-up data of the TOPAZ-1 trial.","authors":"Alexander Olkus, Michael T Dill","doi":"10.21037/hbsn-2025-316","DOIUrl":"10.21037/hbsn-2025-316","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"676-679"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-24DOI: 10.21037/hbsn-2025-221
Stephanie Y Ohara, Michelle C Nguyen, Amit K Mathur, Peter E Frasco, Bashar Aqel, Blanca C Lizaola-Mayo, Caroline C Jadlowiec
{"title":"Updates on the impact of the new liver allocation policy on national liver transplants.","authors":"Stephanie Y Ohara, Michelle C Nguyen, Amit K Mathur, Peter E Frasco, Bashar Aqel, Blanca C Lizaola-Mayo, Caroline C Jadlowiec","doi":"10.21037/hbsn-2025-221","DOIUrl":"10.21037/hbsn-2025-221","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"643-646"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating abdominal surgery in extrahepatic portal vein obstruction: new insights and remaining issues.","authors":"Tetsuya Shimizu, Hiroshi Yoshida, Yoichi Kawano, Akira Matsushita, Masato Yoshioka, Junji Ueda","doi":"10.21037/hbsn-2025-290","DOIUrl":"10.21037/hbsn-2025-290","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"665-668"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-04-25DOI: 10.21037/hbsn-24-552
Silvia Corcione, Damiano Patrono, Nour Shbaklo, Luca Mirabile, Maria Roberta Fortunato, Tommaso Lupia, Paola Maffezzoli, Antonio Curtoni, Alessandro Bondi, Cristina Costa, Renato Romagnoli, Francesco Giuseppe De Rosa
Background: Liver transplantation (LT) is a crucial treatment for end-stage liver disease, but the limited organ supply has led to the use of extended criteria donors (ECD). The implementation of dynamic preservation techniques like hypothermic oxygenated machine perfusion (HOPE) is crucial in improving outcomes for ECD grafts. However, graft contamination and infection are a concern. This study aimed to evaluate the risk of infections within 10 days from LT between HOPE and static cold storage (SCS) groups and postoperative complications.
Methods: A retrospective cohort study was conducted, including LT recipients transplanted at a single-center from March 2016 to June 2023. Patients were divided into HOPE and SCS groups, and propensity score matching was used to select comparable cohorts. Data on patient and donor characteristics were analyzed.
Results: After propensity score matching, a cohort of 370 (HOPE, n=185; SCS, n=185) patients was selected for analysis. The study found no significant differences in the rate of clinically relevant infections, microbiological positive samples, or donor-derived infections within 10 days between HOPE and SCS groups. Postoperative outcomes, as well as patient and graft survival, were also similar between the two groups. The study showed that HOPE is a feasible and safe approach, with a comparable risk of infection.
Conclusions: The study results indicate that HOPE use in LT does not increase the risk of infection and is associated with similar patient and graft survival outcomes compared to SCS. These findings confirm the safety and efficacy of HOPE in LT and its potential to expand the donor pool without compromising recipient outcomes.
{"title":"Hypothermic oxygenated machine perfusion does not increase the risk of infection after liver transplantation: a retrospective cohort study.","authors":"Silvia Corcione, Damiano Patrono, Nour Shbaklo, Luca Mirabile, Maria Roberta Fortunato, Tommaso Lupia, Paola Maffezzoli, Antonio Curtoni, Alessandro Bondi, Cristina Costa, Renato Romagnoli, Francesco Giuseppe De Rosa","doi":"10.21037/hbsn-24-552","DOIUrl":"10.21037/hbsn-24-552","url":null,"abstract":"<p><strong>Background: </strong>Liver transplantation (LT) is a crucial treatment for end-stage liver disease, but the limited organ supply has led to the use of extended criteria donors (ECD). The implementation of dynamic preservation techniques like hypothermic oxygenated machine perfusion (HOPE) is crucial in improving outcomes for ECD grafts. However, graft contamination and infection are a concern. This study aimed to evaluate the risk of infections within 10 days from LT between HOPE and static cold storage (SCS) groups and postoperative complications.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted, including LT recipients transplanted at a single-center from March 2016 to June 2023. Patients were divided into HOPE and SCS groups, and propensity score matching was used to select comparable cohorts. Data on patient and donor characteristics were analyzed.</p><p><strong>Results: </strong>After propensity score matching, a cohort of 370 (HOPE, n=185; SCS, n=185) patients was selected for analysis. The study found no significant differences in the rate of clinically relevant infections, microbiological positive samples, or donor-derived infections within 10 days between HOPE and SCS groups. Postoperative outcomes, as well as patient and graft survival, were also similar between the two groups. The study showed that HOPE is a feasible and safe approach, with a comparable risk of infection.</p><p><strong>Conclusions: </strong>The study results indicate that HOPE use in LT does not increase the risk of infection and is associated with similar patient and graft survival outcomes compared to SCS. These findings confirm the safety and efficacy of HOPE in LT and its potential to expand the donor pool without compromising recipient outcomes.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"562-574"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-25DOI: 10.21037/hbsn-2025-215
Alberto Ferrarese, Andrea Gasperetti, Andrea Ermolao, Giacomo Germani, Patrizia Burra
{"title":"Running towards liver transplantation.","authors":"Alberto Ferrarese, Andrea Gasperetti, Andrea Ermolao, Giacomo Germani, Patrizia Burra","doi":"10.21037/hbsn-2025-215","DOIUrl":"10.21037/hbsn-2025-215","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"697-699"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-24DOI: 10.21037/hbsn-2025-252
Sonal Walia, Alexandra M Roch, Eugene P Ceppa
{"title":"Neuroendocrine liver metastasis.","authors":"Sonal Walia, Alexandra M Roch, Eugene P Ceppa","doi":"10.21037/hbsn-2025-252","DOIUrl":"10.21037/hbsn-2025-252","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"655-657"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-25DOI: 10.21037/hbsn-2025-139
Congwei Jia, Jinyi Meng, Can Yin, Xuemei Sun, Yan You, Lei Zhang, Xiaoyan Chang
{"title":"Primary Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma concurrent with lymphoepithelioma-like intrahepatic cholangiocarcinoma and cavernous hemangioma in liver.","authors":"Congwei Jia, Jinyi Meng, Can Yin, Xuemei Sun, Yan You, Lei Zhang, Xiaoyan Chang","doi":"10.21037/hbsn-2025-139","DOIUrl":"10.21037/hbsn-2025-139","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"716-719"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}