Pub Date : 2026-02-19DOI: 10.1177/15589447261416972
Kathryn Culliton, Kendrick Au, Sebastian Undurraga, Hakim Louati, Heathcliff D'Sa, Braden Gammon
Background: TDetection of distal radioulnar joint (DRUJ) instability has proven inconsistent despite numerous examination maneuvers. Computed tomography (CT) has been suggested as a modality for evaluating DRUJ instability; however, without stress across the DRUJ, it fails to reliably identify this. No study has simultaneously assessed stress CT with clinical stress maneuvers. As such, the purpose of this study was to compare both methods in stable and unstable wrists.
Methods: An arthrometer was developed to evaluate a clinical stress test of the DRUJ in various degrees of forearm rotation. In each forearm position, specimens were subjected to standardized volar and dorsal loads to simulate clinical stress to the DRUJ. Computed tomography images were acquired in each position with additional unstressed images. The triangular fibrocartilage complex (TFCC) was then sectioned to simulate DRUJ instability.
Results: Nine upper extremities were used. The arthrometer could detect a significant difference between sectioned and intact TFCCs in the supinated forearm position. A large proportion of the translation measured by the arthrometer was due to rotation within the clamps. In the unstressed state, CT analysis using the radioulnar ratio failed to show significant differences in DRUJ stability for any forearm orientation. By applying stress across the DRUJ, CT analysis of ulnar translation along the sigmoid notch showed significant differences between TFCC intact and sectioned wrists.
Conclusions: Clinical examination maneuvers and arthrometers are observing a rotational component that occurs due to the inability to directly clamp the underlying bone, whereas stress CT is more accurate for quantifying underlying bony translation. Unstressed CT analysis did not identify instability.
{"title":"A Biomechanical Analysis of the Distal Radioulnar Joint Ballottement Test Using Stress CT.","authors":"Kathryn Culliton, Kendrick Au, Sebastian Undurraga, Hakim Louati, Heathcliff D'Sa, Braden Gammon","doi":"10.1177/15589447261416972","DOIUrl":"https://doi.org/10.1177/15589447261416972","url":null,"abstract":"<p><strong>Background: </strong>TDetection of distal radioulnar joint (DRUJ) instability has proven inconsistent despite numerous examination maneuvers. Computed tomography (CT) has been suggested as a modality for evaluating DRUJ instability; however, without stress across the DRUJ, it fails to reliably identify this. No study has simultaneously assessed stress CT with clinical stress maneuvers. As such, the purpose of this study was to compare both methods in stable and unstable wrists.</p><p><strong>Methods: </strong>An arthrometer was developed to evaluate a clinical stress test of the DRUJ in various degrees of forearm rotation. In each forearm position, specimens were subjected to standardized volar and dorsal loads to simulate clinical stress to the DRUJ. Computed tomography images were acquired in each position with additional unstressed images. The triangular fibrocartilage complex (TFCC) was then sectioned to simulate DRUJ instability.</p><p><strong>Results: </strong>Nine upper extremities were used. The arthrometer could detect a significant difference between sectioned and intact TFCCs in the supinated forearm position. A large proportion of the translation measured by the arthrometer was due to rotation within the clamps. In the unstressed state, CT analysis using the radioulnar ratio failed to show significant differences in DRUJ stability for any forearm orientation. By applying stress across the DRUJ, CT analysis of ulnar translation along the sigmoid notch showed significant differences between TFCC intact and sectioned wrists.</p><p><strong>Conclusions: </strong>Clinical examination maneuvers and arthrometers are observing a rotational component that occurs due to the inability to directly clamp the underlying bone, whereas stress CT is more accurate for quantifying underlying bony translation. Unstressed CT analysis did not identify instability.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447261416972"},"PeriodicalIF":1.8,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-16DOI: 10.1177/15589447251413729
Haley Nakata, Jackson M Cathey, Ethan Y Song, James P Fischer, Daniel J Lorenzana, Warren C Hammert, David S Ruch, Tyler S Pidgeon
Background: The scaphoid height-to-length (H/L) ratio assesses reduction quality, with lower values indicating better anatomic restoration and reduced malunion risk. We hypothesized that dorsal percutaneous fixation of acute, unstable distal oblique fractures yields a lower postoperative H/L ratio compared with volar fixation.
Methods: We retrospectively reviewed all Herbert B1 fractures treated with percutaneous screw fixation at a single, tertiary referral center over 10 years. Dorsal and volar approaches followed standardized protocols, with guidewire placement under fluoroscopy and headless compression screw fixation. Postoperative computed tomography (CT) assessed the H/L ratio, intrascaphoid angle (ISA), and dorsal cortical angle (DCA), reformatted along the long axis of the scaphoid. Demographics, injury/operative characteristics, CT-based metrics, and clinical outcomes were compared between approaches.
Results: A total of 18 patients met inclusion criteria (dorsal n = 10, volar n = 8), with an average follow-up of 7.3 months. The cohorts did not significantly differ in demographic, injury, or operative covariates. Computed tomography assessment showed similar ISA and DCA, but a lower H/L ratio in the dorsal approach cohort (0.64 vs 0.70, P = .040). While functional outcomes were mostly comparable, dorsal approach patients reported lower Disability of the Arm, Shoulder, and Hand scores at final follow-up (17.7 vs 45.5, P = .019). Two of the 18 patients developed nonunion; both were treated via a dorsal approach.
Conclusions: A dorsal approach may achieve more anatomic reduction in percutaneous screw fixation of distal oblique scaphoid fractures, though it remains unclear whether the approach has any meaningful, relative influence on functional outcome and bone union.
背景:舟状骨高长比(H/L)评估复位质量,数值越低表明解剖修复越好,畸形愈合风险越低。我们假设,与掌侧固定相比,背侧经皮固定治疗急性不稳定远端斜骨折术后H/L比更低。方法:我们回顾性回顾了10年来在单一三级转诊中心经皮螺钉固定治疗的所有Herbert B1骨折。背侧和掌侧入路采用标准化方案,在透视下放置导丝,无头加压螺钉固定。术后计算机断层扫描(CT)评估沿舟状骨长轴重构的H/L比、舟状骨内角(ISA)和背皮质角(DCA)。比较两种方法的人口统计学、损伤/手术特征、基于ct的指标和临床结果。结果:18例患者符合纳入标准(背侧10例,掌侧8例),平均随访7.3个月。这些队列在人口统计学、损伤或手术协变量方面没有显著差异。计算机断层扫描评估显示ISA和DCA相似,但在背侧入路队列中H/L比较低(0.64 vs 0.70, P = 0.040)。虽然功能结果大多具有可比性,但在最终随访时,背侧入路患者报告的手臂、肩部和手部残疾评分较低(17.7 vs 45.5, P = 0.019)。18例患者中有2例出现骨不连;两例均经背侧入路治疗。结论:背侧入路在经皮经皮螺钉固定远侧斜舟状骨骨折时可实现更多解剖复位,但目前尚不清楚该入路是否对功能结局和骨愈合有任何有意义的相对影响。
{"title":"Percutaneous Screw Fixation for Distal Oblique Scaphoid Fractures: A Computed Tomography-Based Evaluation of the Dorsal and Volar Approach.","authors":"Haley Nakata, Jackson M Cathey, Ethan Y Song, James P Fischer, Daniel J Lorenzana, Warren C Hammert, David S Ruch, Tyler S Pidgeon","doi":"10.1177/15589447251413729","DOIUrl":"10.1177/15589447251413729","url":null,"abstract":"<p><strong>Background: </strong>The scaphoid height-to-length (H/L) ratio assesses reduction quality, with lower values indicating better anatomic restoration and reduced malunion risk. We hypothesized that dorsal percutaneous fixation of acute, unstable distal oblique fractures yields a lower postoperative H/L ratio compared with volar fixation.</p><p><strong>Methods: </strong>We retrospectively reviewed all Herbert B1 fractures treated with percutaneous screw fixation at a single, tertiary referral center over 10 years. Dorsal and volar approaches followed standardized protocols, with guidewire placement under fluoroscopy and headless compression screw fixation. Postoperative computed tomography (CT) assessed the H/L ratio, intrascaphoid angle (ISA), and dorsal cortical angle (DCA), reformatted along the long axis of the scaphoid. Demographics, injury/operative characteristics, CT-based metrics, and clinical outcomes were compared between approaches.</p><p><strong>Results: </strong>A total of 18 patients met inclusion criteria (dorsal n = 10, volar n = 8), with an average follow-up of 7.3 months. The cohorts did not significantly differ in demographic, injury, or operative covariates. Computed tomography assessment showed similar ISA and DCA, but a lower H/L ratio in the dorsal approach cohort (0.64 vs 0.70, <i>P</i> = .040). While functional outcomes were mostly comparable, dorsal approach patients reported lower Disability of the Arm, Shoulder, and Hand scores at final follow-up (17.7 vs 45.5, <i>P</i> = .019). Two of the 18 patients developed nonunion; both were treated via a dorsal approach.</p><p><strong>Conclusions: </strong>A dorsal approach may achieve more anatomic reduction in percutaneous screw fixation of distal oblique scaphoid fractures, though it remains unclear whether the approach has any meaningful, relative influence on functional outcome and bone union.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251413729"},"PeriodicalIF":1.8,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12913037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-16DOI: 10.1177/15589447261416976
Jared Reid, Colin Zieminski, J Ambrose Martino, Julia DeSalvo, Dane Daley, Charles Daly
Background: Peripheral nerve injuries (PNIs) are a significant cause of global disability, often leading to lifelong sensory and motor deficits. Increasing efforts to unveil the psychosocial implications of such injuries is being made. The aim of this study was to determine the impact of preoperatively diagnosed mental health disorder (MHD), specifically major depressive disorder (MDD), generalized anxiety disorder (GAD), and post-traumatic stress disorder (PTSD), on short-term outcomes following PNI repair.
Methods: A large, retrospective cohort, using the TriNetX Collaborative Global Network database queried on April 9, 2025, was used to identify patients undergoing PNI repair with preoperative MHD diagnoses. Propensity matching was performed, allowing analysis of 30-day and 90-day postoperative outcomes in patients with MHD along with subgroup analysis of those diagnosed with MDD, GAD, or PTSD.
Results: Mental health disorder (n = 2521), MDD (n = 1107), GAD (n = 996), and PTSD (n = 938) groups were found to have increased emergency department use and hospital readmission postoperatively. Patients with MHD were less likely to attend outpatient follow-up in clinic or use occupational therapy services. Complications and opioid consumptions were similar among all groups.
Conclusions: Following PNI repair, patients with pre-existing MHD demonstrated increased hospital resource utilization and decreased outpatient follow-up despite similar complication and opioid use rates. The need for a comprehensive, multifaceted approach to optimize treatment outcomes following PNI, specifically those with concomitant MHD, is obviated by the findings in this study.
{"title":"Effects of Mental Health on 30-Day Postoperative Outcomes Following Peripheral Nerve Repair.","authors":"Jared Reid, Colin Zieminski, J Ambrose Martino, Julia DeSalvo, Dane Daley, Charles Daly","doi":"10.1177/15589447261416976","DOIUrl":"10.1177/15589447261416976","url":null,"abstract":"<p><strong>Background: </strong>Peripheral nerve injuries (PNIs) are a significant cause of global disability, often leading to lifelong sensory and motor deficits. Increasing efforts to unveil the psychosocial implications of such injuries is being made. The aim of this study was to determine the impact of preoperatively diagnosed mental health disorder (MHD), specifically major depressive disorder (MDD), generalized anxiety disorder (GAD), and post-traumatic stress disorder (PTSD), on short-term outcomes following PNI repair.</p><p><strong>Methods: </strong>A large, retrospective cohort, using the TriNetX Collaborative Global Network database queried on April 9, 2025, was used to identify patients undergoing PNI repair with preoperative MHD diagnoses. Propensity matching was performed, allowing analysis of 30-day and 90-day postoperative outcomes in patients with MHD along with subgroup analysis of those diagnosed with MDD, GAD, or PTSD.</p><p><strong>Results: </strong>Mental health disorder (n = 2521), MDD (n = 1107), GAD (n = 996), and PTSD (n = 938) groups were found to have increased emergency department use and hospital readmission postoperatively. Patients with MHD were less likely to attend outpatient follow-up in clinic or use occupational therapy services. Complications and opioid consumptions were similar among all groups.</p><p><strong>Conclusions: </strong>Following PNI repair, patients with pre-existing MHD demonstrated increased hospital resource utilization and decreased outpatient follow-up despite similar complication and opioid use rates. The need for a comprehensive, multifaceted approach to optimize treatment outcomes following PNI, specifically those with concomitant MHD, is obviated by the findings in this study.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447261416976"},"PeriodicalIF":1.8,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.1177/15589447251414125
Michelle Richardson, Adam Margalit, Gerardo Sanchez, Peter Ren, Samara Moll, Liana Tedesco, Jadie De Tolla, Jacques Hacquebord, Omri Ayalon
Background: The purpose of this study is to compare outcomes in patients with isolated unrepairable scapholunate (SL) injuries treated with the reduction and association of the scaphoid and lunate (RASL) screw technique versus suture anchors with an internal brace (IB).
Methods: Patients treated with either the RASL screw or IB technique for a complete, nonrepairable SL injury were identified. Radiographic and clinical data were recorded preoperatively, immediate postoperatively, and at final follow-up. Patients were then contacted via telephone survey, and Quick Disabilities of the Arm, Shoulder, and Hand (qDASH) questionnaire was administered. Patients with less than 6 months of follow-up were excluded.
Results: Twenty-five patients (19 men, 6 women) with an average age of 43 (range = 23-66) years were identified (RASL = 14 and IB = 11). There were no differences between groups in radiographic parameters or range of motion at final follow-up, except for a smaller SL gap at final follow-up in RASL patients (1.5 vs 2.4 mm, P = .03). Four patients in the RASL (29%) group required additional procedures for screw removal secondary to screw breakage (n = 1) or screw migration/loosening (n = 3). One patient in the IB group had complete failure/diastasis postoperatively, and 36% (4/11) of patients had osteolysis at final follow-up. At final follow-up, qDASH was 26 versus 31 in the IB versus RASL groups (P = .79).
Conclusions: Both RASL and IB have similar postoperative outcomes when treating SL injuries. It is important to note complications of screw breakage/loosening associated with RASL and recurrent diastasis/gapping and high rate of osteolysis with IB, although this has an unknown clinical significance.
背景:本研究的目的是比较孤立的不可修复的舟月骨(SL)损伤患者采用舟月骨和月骨(RASL)螺钉复位和联合技术与内支架(IB)缝合锚钉治疗的结果。方法:采用RASL螺钉或IB技术治疗完全性、不可修复的SL损伤的患者。术前、术后及最后随访时记录影像学和临床资料。然后通过电话调查与患者联系,并进行手臂,肩膀和手的快速残疾(qDASH)问卷调查。随访时间少于6个月的患者被排除。结果:25例患者(男19例,女6例),平均年龄43岁(范围23 ~ 66岁),RASL = 14, IB = 11。除了RASL患者最终随访时SL间隙较小(1.5 mm vs 2.4 mm, P = .03)外,两组之间在放射学参数或活动范围方面没有差异。RASL组中有4例(29%)患者因螺钉断裂(n = 1)或螺钉移动/松动(n = 3)需要进行额外的螺钉拆卸手术。IB组1例患者术后完全失活/转移,36%(4/11)患者在最终随访时出现骨溶解。在最终随访时,IB组和RASL组的qDASH分别为26和31 (P = 0.79)。结论:RASL和IB治疗SL损伤的术后效果相似。值得注意的是,与RASL相关的螺钉断裂/松动、复发性移位/间隙和IB高溶骨率的并发症,尽管其临床意义尚不清楚。
{"title":"Reduction and Association of the Scaphoid and Lunate Versus Internal Brace for Scapholunate Ligament Reconstruction.","authors":"Michelle Richardson, Adam Margalit, Gerardo Sanchez, Peter Ren, Samara Moll, Liana Tedesco, Jadie De Tolla, Jacques Hacquebord, Omri Ayalon","doi":"10.1177/15589447251414125","DOIUrl":"10.1177/15589447251414125","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study is to compare outcomes in patients with isolated unrepairable scapholunate (SL) injuries treated with the reduction and association of the scaphoid and lunate (RASL) screw technique versus suture anchors with an internal brace (IB).</p><p><strong>Methods: </strong>Patients treated with either the RASL screw or IB technique for a complete, nonrepairable SL injury were identified. Radiographic and clinical data were recorded preoperatively, immediate postoperatively, and at final follow-up. Patients were then contacted via telephone survey, and Quick Disabilities of the Arm, Shoulder, and Hand (qDASH) questionnaire was administered. Patients with less than 6 months of follow-up were excluded.</p><p><strong>Results: </strong>Twenty-five patients (19 men, 6 women) with an average age of 43 (range = 23-66) years were identified (RASL = 14 and IB = 11). There were no differences between groups in radiographic parameters or range of motion at final follow-up, except for a smaller SL gap at final follow-up in RASL patients (1.5 vs 2.4 mm, P = .03). Four patients in the RASL (29%) group required additional procedures for screw removal secondary to screw breakage (n = 1) or screw migration/loosening (n = 3). One patient in the IB group had complete failure/diastasis postoperatively, and 36% (4/11) of patients had osteolysis at final follow-up. At final follow-up, qDASH was 26 versus 31 in the IB versus RASL groups (P = .79).</p><p><strong>Conclusions: </strong>Both RASL and IB have similar postoperative outcomes when treating SL injuries. It is important to note complications of screw breakage/loosening associated with RASL and recurrent diastasis/gapping and high rate of osteolysis with IB, although this has an unknown clinical significance.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251414125"},"PeriodicalIF":1.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.1177/15589447261415641
Haley D Puckett, Jacob S Borgida, Stephen A Doxey, Rebekah M Kleinsmith, Deborah C Bohn, Jeffrey B Husband, Brian P Cunningham
Background: Distal radius fractures (DRFs) are a common orthopedic injury. Patient-reported outcomes (PROs) and achievement of the minimum clinically important difference (MCID) provide insight into functional recovery. The purpose of this study was to evaluate the impact of patient characteristics, particularly anxiety, on PROs and MCID achievement following DRF.
Methods: All adult patients undergoing primary operative fixation of a DRF at a single health system between 2018 and 2023 were identified. Exclusions included polytrauma, fixation besides a volar locking plate, or missing PROs at baseline or any postoperative follow-up. The Patient-Rated Wrist Evaluation (PRWE) was collected preoperatively and at 6 weeks, 3 months, and 6 months postoperatively. An anchor-based MCID was calculated using a general health question.
Results: Seventy-eight patients were included (87.2% female, average age 62.4 ± 12.5 years). Fifty-nine patients (75.6%) had intraarticular fractures. Depression was more common in the anxiety cohort (68.4% vs 20.3%, P < .001). The MCID thresholds at 3 and 6 months were 57.7 and 61.8, respectively. Patients with anxiety had lower MCID achievement at 6 months (31.6% vs 59.3%, P = .035) and smaller PRWE improvements (P = .002). The PRWE scores at 6 weeks and 3 months were moderately correlated with 6-month scores (r = .51, r = .58, respectively), and 3-month changes were strongly correlated with 6-month changes (r = .73)Conclusions:Anxiety was associated with smaller improvements in PRWE scores and reduced MCID achievement, highlighting the importance of addressing mental health in postoperative care. Early PRWE scores were moderately predictive of 6-month scores, suggesting that patients with limited early improvement may benefit from targeted interventions to optimize long-term recovery.
背景:桡骨远端骨折(DRFs)是一种常见的骨科损伤。患者报告的结果(PROs)和最小临床重要差异(MCID)的实现提供了对功能恢复的洞察。本研究的目的是评估患者特征,特别是焦虑,对DRF后PROs和MCID成就的影响。方法:对2018年至2023年间在单一卫生系统接受DRF初次手术固定的所有成年患者进行分析。排除包括多发外伤、掌侧锁定钢板以外的固定、基线或任何术后随访时缺少PROs。术前、术后6周、3个月和6个月收集患者腕关节评估(PRWE)。使用一般健康问题计算基于锚点的MCID。结果:纳入患者78例(女性87.2%,平均年龄62.4±12.5岁)。59例(75.6%)发生关节内骨折。抑郁在焦虑组中更为常见(68.4% vs 20.3%, P < 0.001)。3个月和6个月时的MCID阈值分别为57.7和61.8。焦虑患者在6个月时的MCID成就较低(31.6% vs 59.3%, P = 0.035), PRWE改善较小(P = 0.002)。6周和3个月的PRWE评分与6个月评分中度相关(r = 0.51, r = 0.58), 3个月的变化与6个月的变化强烈相关(r = 0.73)结论:焦虑与PRWE评分的小幅改善和MCID成就的降低相关,强调了在术后护理中处理心理健康的重要性。早期PRWE评分可适度预测6个月评分,这表明早期改善有限的患者可能受益于有针对性的干预措施,以优化长期恢复。
{"title":"Anxiety and the Attainment of Clinically Significant Outcomes in Operatively Treated Distal Radius Fracture Patients: A Retrospective Study of 78 Patients.","authors":"Haley D Puckett, Jacob S Borgida, Stephen A Doxey, Rebekah M Kleinsmith, Deborah C Bohn, Jeffrey B Husband, Brian P Cunningham","doi":"10.1177/15589447261415641","DOIUrl":"10.1177/15589447261415641","url":null,"abstract":"<p><strong>Background: </strong>Distal radius fractures (DRFs) are a common orthopedic injury. Patient-reported outcomes (PROs) and achievement of the minimum clinically important difference (MCID) provide insight into functional recovery. The purpose of this study was to evaluate the impact of patient characteristics, particularly anxiety, on PROs and MCID achievement following DRF.</p><p><strong>Methods: </strong>All adult patients undergoing primary operative fixation of a DRF at a single health system between 2018 and 2023 were identified. Exclusions included polytrauma, fixation besides a volar locking plate, or missing PROs at baseline or any postoperative follow-up. The Patient-Rated Wrist Evaluation (PRWE) was collected preoperatively and at 6 weeks, 3 months, and 6 months postoperatively. An anchor-based MCID was calculated using a general health question.</p><p><strong>Results: </strong>Seventy-eight patients were included (87.2% female, average age 62.4 ± 12.5 years). Fifty-nine patients (75.6%) had intraarticular fractures. Depression was more common in the anxiety cohort (68.4% vs 20.3%, <i>P</i> < .001). The MCID thresholds at 3 and 6 months were 57.7 and 61.8, respectively. Patients with anxiety had lower MCID achievement at 6 months (31.6% vs 59.3%, <i>P</i> = .035) and smaller PRWE improvements (<i>P</i> = .002). The PRWE scores at 6 weeks and 3 months were moderately correlated with 6-month scores (<i>r</i> = .51, <i>r</i> = .58, respectively), and 3-month changes were strongly correlated with 6-month changes (<i>r</i> = .73)Conclusions:Anxiety was associated with smaller improvements in PRWE scores and reduced MCID achievement, highlighting the importance of addressing mental health in postoperative care. Early PRWE scores were moderately predictive of 6-month scores, suggesting that patients with limited early improvement may benefit from targeted interventions to optimize long-term recovery.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447261415641"},"PeriodicalIF":1.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.1177/15589447251415377
Joshua K Kim, Alyssa R Henriquez, Hani I Naga, Suhail K Mithani, Warren C Hammert
Background: TSymptomatic thumb carpometacarpal arthritis refractory to nonoperative treatment often results in carpometacarpal arthroplasty surgery. Postoperative therapy facilitates functional recovery, but there may be barriers that can affect recovery and final outcomes. This study identified socioeconomic or functional factors influencing therapy attendance after surgery and patient outcomes.
Methods: Patients at a single academic institution from 2014 to 2024 with carpometacarpal osteoarthritis undergoing carpometacarpal arthroplasty surgery were reviewed. Demographics, postoperative clinic and therapy visits, Patient-Reported Outcomes Measurement Information System scores, and Quick Disabilities of the Arm, Shoulder, and Hand scores were tallied. Bivariate analysis compared patients attending 5 or more therapy sessions with those who did not. Area of deprivation was used to divide patients for analysis.
Results: A total of 1259 patients were eligible for inclusion, with 1078 (85.6%) attending hand therapy for 4 [2, 7] sessions over 7.4 [3.6, 12.1] weeks. Socioeconomically disadvantaged patients had fewer therapy visits but no worse functional outcomes. Patients engaging in consistent therapy reported worse pain interference, physical function, and upper extremity function at 6 weeks relative to those attending fewer sessions (all P < .05). Function nearly equalized at 3 months, and at 6 months, consistent therapy patients achieved more favorable Pain Interference and Physical Function scores (P < .05).
Conclusion: Patients with carpometacarpal osteoarthritis exhibit high therapy attendance following surgery. Socioeconomically disadvantaged patients attended fewer therapy sessions but had comparable functional outcomes. Patients with poorer functional scores at 6 weeks tended to attend therapy longitudinally. At latest follow-up however, their function exceeded non-participants. Therapy attendance is influenced by socioeconomic factors and natural functional recovery.
{"title":"Characterizing Hand Therapy Participation Following Trapeziectomy for Carpometacarpal Osteoarthritis.","authors":"Joshua K Kim, Alyssa R Henriquez, Hani I Naga, Suhail K Mithani, Warren C Hammert","doi":"10.1177/15589447251415377","DOIUrl":"10.1177/15589447251415377","url":null,"abstract":"<p><strong>Background: </strong>TSymptomatic thumb carpometacarpal arthritis refractory to nonoperative treatment often results in carpometacarpal arthroplasty surgery. Postoperative therapy facilitates functional recovery, but there may be barriers that can affect recovery and final outcomes. This study identified socioeconomic or functional factors influencing therapy attendance after surgery and patient outcomes.</p><p><strong>Methods: </strong>Patients at a single academic institution from 2014 to 2024 with carpometacarpal osteoarthritis undergoing carpometacarpal arthroplasty surgery were reviewed. Demographics, postoperative clinic and therapy visits, Patient-Reported Outcomes Measurement Information System scores, and Quick Disabilities of the Arm, Shoulder, and Hand scores were tallied. Bivariate analysis compared patients attending 5 or more therapy sessions with those who did not. Area of deprivation was used to divide patients for analysis.</p><p><strong>Results: </strong>A total of 1259 patients were eligible for inclusion, with 1078 (85.6%) attending hand therapy for 4 [2, 7] sessions over 7.4 [3.6, 12.1] weeks. Socioeconomically disadvantaged patients had fewer therapy visits but no worse functional outcomes. Patients engaging in consistent therapy reported worse pain interference, physical function, and upper extremity function at 6 weeks relative to those attending fewer sessions (all P < .05). Function nearly equalized at 3 months, and at 6 months, consistent therapy patients achieved more favorable Pain Interference and Physical Function scores (P < .05).</p><p><strong>Conclusion: </strong>Patients with carpometacarpal osteoarthritis exhibit high therapy attendance following surgery. Socioeconomically disadvantaged patients attended fewer therapy sessions but had comparable functional outcomes. Patients with poorer functional scores at 6 weeks tended to attend therapy longitudinally. At latest follow-up however, their function exceeded non-participants. Therapy attendance is influenced by socioeconomic factors and natural functional recovery.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251415377"},"PeriodicalIF":1.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.1177/15589447261416993
Anagh Astavans, Indeevar R Beeram, Dawn M LaPorte
Background: Triangular fibrocartilage complex (TFCC) injuries are common in athletes and may lead to substantial pain and functional limitations. This study characterizes TFCC injuries in athletes, particularly those involved in racquet sports. We also report on treatment patterns, patient outcomes, and risk factors for TFCC injury.
Methods: Patients with soft tissue injuries of the wrist at our institution in the last 9 years were screened for diagnosis of TFCC injury associated with racquet sports. Patients were excluded if there was no record of treatment or follow-up after diagnosis. Retrospective chart review was performed to collect data on demographics, injury and treatment specifics, return to baseline activity (RTBA) time after initiating treatment, and complications.
Results: Of 700 patients diagnosed with TFCC injury, 23.1% sustained injury during sports. Twenty-five (15.4%) were playing a racquet sport, most commonly tennis (n = 21). Five patients were excluded according to exclusion criteria. Fifty-five percent of the included patients were men, adolescents, and played their sport competitively. Seventy-five percent injured their dominant wrist, with 35% sustaining an ulnar-sided tear. Fifteen patients were treated nonoperatively through wrist immobilization and therapy. Of the 5 surgically treated patients, 4 underwent arthroscopic debridement while 1 underwent open repair. Seventeen patients (12 nonoperative and all surgical) were able to RTBA (average time: 134 days), of which only one had pain recurrence.
Conclusions: Triangular fibrocartilage complex injuries disproportionately affect tennis players but favorably resolved from nonoperative treatment in 73.3% of cases and from surgery in all cases. Prior TFCC pathology and age above 50 were associated with no RTBA.
{"title":"Triangular Fibrocartilage Complex Injuries in Racquet Sport Players: Prevalence, Management, and Outcomes.","authors":"Anagh Astavans, Indeevar R Beeram, Dawn M LaPorte","doi":"10.1177/15589447261416993","DOIUrl":"10.1177/15589447261416993","url":null,"abstract":"<p><strong>Background: </strong>Triangular fibrocartilage complex (TFCC) injuries are common in athletes and may lead to substantial pain and functional limitations. This study characterizes TFCC injuries in athletes, particularly those involved in racquet sports. We also report on treatment patterns, patient outcomes, and risk factors for TFCC injury.</p><p><strong>Methods: </strong>Patients with soft tissue injuries of the wrist at our institution in the last 9 years were screened for diagnosis of TFCC injury associated with racquet sports. Patients were excluded if there was no record of treatment or follow-up after diagnosis. Retrospective chart review was performed to collect data on demographics, injury and treatment specifics, return to baseline activity (RTBA) time after initiating treatment, and complications.</p><p><strong>Results: </strong>Of 700 patients diagnosed with TFCC injury, 23.1% sustained injury during sports. Twenty-five (15.4%) were playing a racquet sport, most commonly tennis (n = 21). Five patients were excluded according to exclusion criteria. Fifty-five percent of the included patients were men, adolescents, and played their sport competitively. Seventy-five percent injured their dominant wrist, with 35% sustaining an ulnar-sided tear. Fifteen patients were treated nonoperatively through wrist immobilization and therapy. Of the 5 surgically treated patients, 4 underwent arthroscopic debridement while 1 underwent open repair. Seventeen patients (12 nonoperative and all surgical) were able to RTBA (average time: 134 days), of which only one had pain recurrence.</p><p><strong>Conclusions: </strong>Triangular fibrocartilage complex injuries disproportionately affect tennis players but favorably resolved from nonoperative treatment in 73.3% of cases and from surgery in all cases. Prior TFCC pathology and age above 50 were associated with no RTBA.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447261416993"},"PeriodicalIF":1.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.1177/15589447251415390
Richard W McKinney, Anna Barclay, Jacob Sneddon, Patrick J Schimoler, Alexander Kharlamov, Boyle Cheng, Peter Tang
Background: Flexor tendon injuries remain a challenge for hand surgeons. The constraints of the pulley system with the need for a strong repair require a delicate balance. Suture repair has been the gold standard. The 4-strand locked cruciate stitch is the technique of choice for many. This can be laborious and technically difficult. Tendon stapler devices (TSDs) aim to provide fast, strong, low-profile repairs. Industry data have shown stronger TSD repairs compared with suture repair techniques. We aim to further explore the relative strengths of TSD and 4-strand locked cruciate repairs in cadavers.
Methods: Twenty-four flexor tendons were used for 12 suture repairs and 12 TSD repairs. Four-strand locked cruciate repairs used 3-0 braided composite suture. The TSD repairs used CoNextions devices. Specimens were analyzed on a uniaxial load frame and distracted at 0.5 mm/s. Tension was recorded at 100 Hz. A camera system measured reference point positions at 10 Hz. Maximum tension and tension at 2-mm gap formation were recorded. Independent t-tests were used to compare groups, with significance noted by P < .05.
Results: Load to failure for the staple group and suture group were 70.6 ± 20.5 N and 49.9 ± 14.1 N, respectively. Load to 2-mm gap for the staple group and the suture group were 57.5 ± 21.1 N and 38.6 ± 13.7 N, respectively. Mean load to failure and load to 2-mm gap were significantly greater in the TSD group.
Conclusions: In this study, TSD repairs were stronger than the 4-strand locked cruciate suture repair. Further clinical studies and cost analyses are necessary to support their widespread use.
{"title":"Tendon Stapler Device Versus Traditional Suture Repair for Flexor Tendon Injuries: A Biomechanical Comparison.","authors":"Richard W McKinney, Anna Barclay, Jacob Sneddon, Patrick J Schimoler, Alexander Kharlamov, Boyle Cheng, Peter Tang","doi":"10.1177/15589447251415390","DOIUrl":"10.1177/15589447251415390","url":null,"abstract":"<p><strong>Background: </strong>Flexor tendon injuries remain a challenge for hand surgeons. The constraints of the pulley system with the need for a strong repair require a delicate balance. Suture repair has been the gold standard. The 4-strand locked cruciate stitch is the technique of choice for many. This can be laborious and technically difficult. Tendon stapler devices (TSDs) aim to provide fast, strong, low-profile repairs. Industry data have shown stronger TSD repairs compared with suture repair techniques. We aim to further explore the relative strengths of TSD and 4-strand locked cruciate repairs in cadavers.</p><p><strong>Methods: </strong>Twenty-four flexor tendons were used for 12 suture repairs and 12 TSD repairs. Four-strand locked cruciate repairs used 3-0 braided composite suture. The TSD repairs used CoNextions devices. Specimens were analyzed on a uniaxial load frame and distracted at 0.5 mm/s. Tension was recorded at 100 Hz. A camera system measured reference point positions at 10 Hz. Maximum tension and tension at 2-mm gap formation were recorded. Independent t-tests were used to compare groups, with significance noted by P < .05.</p><p><strong>Results: </strong>Load to failure for the staple group and suture group were 70.6 ± 20.5 N and 49.9 ± 14.1 N, respectively. Load to 2-mm gap for the staple group and the suture group were 57.5 ± 21.1 N and 38.6 ± 13.7 N, respectively. Mean load to failure and load to 2-mm gap were significantly greater in the TSD group.</p><p><strong>Conclusions: </strong>In this study, TSD repairs were stronger than the 4-strand locked cruciate suture repair. Further clinical studies and cost analyses are necessary to support their widespread use.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251415390"},"PeriodicalIF":1.8,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-10DOI: 10.1177/15589447251415387
Ethan Blum, Mitch S Mologne, Julia M Perugini, David M Brogan, Christopher J Dy
Ballistic peripheral nerve injuries (PNIs) are a distinct and complex form of nerve trauma caused by high-energy mechanisms and frequently accompanied by soft tissue and skeletal damage. Despite their prevalence in both military and civilian trauma, the literature on diagnosis, timing, treatment, and outcomes remains fragmented. We conducted a systematic review of PubMed, Embase, and Scopus (1975-2025) following Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and included 27 studies with more than 2500 patients that reported original data on ballistic PNIs. Diagnostic approaches were inconsistent, with variable use of electrodiagnostics, imaging, and clinical assessment. The timing of diagnosis and surgery ranged from days to more than a year postinjury, and surgical strategies included neurolysis, direct repair, and nerve grafting. Outcome reporting was heterogeneous, with motor recovery often assessed using the Medical Research Council scale, while sensory and functional outcomes were less consistently measured and rarely evaluated with validated instruments. Across studies, many patients achieved partial motor recovery, but the lack of standardized diagnostic protocols and uniform outcome measures limited comparability. Overall, the evaluation and management of ballistic PNIs remain highly variable, underscoring the need for standardized diagnostic pathways and consistent, validated outcome reporting to guide future research and clinical care.
{"title":"Ballistic Nerve Injuries of the Extremities: A Systematic Review of Diagnosis, Timing, Treatment, and Outcomes.","authors":"Ethan Blum, Mitch S Mologne, Julia M Perugini, David M Brogan, Christopher J Dy","doi":"10.1177/15589447251415387","DOIUrl":"10.1177/15589447251415387","url":null,"abstract":"<p><p>Ballistic peripheral nerve injuries (PNIs) are a distinct and complex form of nerve trauma caused by high-energy mechanisms and frequently accompanied by soft tissue and skeletal damage. Despite their prevalence in both military and civilian trauma, the literature on diagnosis, timing, treatment, and outcomes remains fragmented. We conducted a systematic review of PubMed, Embase, and Scopus (1975-2025) following Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and included 27 studies with more than 2500 patients that reported original data on ballistic PNIs. Diagnostic approaches were inconsistent, with variable use of electrodiagnostics, imaging, and clinical assessment. The timing of diagnosis and surgery ranged from days to more than a year postinjury, and surgical strategies included neurolysis, direct repair, and nerve grafting. Outcome reporting was heterogeneous, with motor recovery often assessed using the Medical Research Council scale, while sensory and functional outcomes were less consistently measured and rarely evaluated with validated instruments. Across studies, many patients achieved partial motor recovery, but the lack of standardized diagnostic protocols and uniform outcome measures limited comparability. Overall, the evaluation and management of ballistic PNIs remain highly variable, underscoring the need for standardized diagnostic pathways and consistent, validated outcome reporting to guide future research and clinical care.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251415387"},"PeriodicalIF":1.8,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-08DOI: 10.1177/15589447251415393
Jeffrey Coombs, Christopher M Dussik, Amy Phan, Joseph Ferraro, Danielle Wilbur, Constantinos Ketonis
Background: The optimal surgical strategy for carpal tunnel release remains a subject of debate. This study compared the perioperative complication rates of endoscopic and open carpal tunnel release for the treatment of carpal tunnel syndrome in patients with nicotine dependence.
Methods: The TriNetX database was queried to conduct a retrospective cohort study, identifying a total of 22 435 open carpal tunnel releases and 4947 endoscopic carpal tunnel releases performed on patients with nicotine dependence. Short-term, 90-day complication rates were assessed across both cohorts, including hospital admissions, postoperative emergency department (ED) visits, infections, nerve injury, renal injury, and thrombotic events. Propensity score-matched analyses were performed to mitigate the risk of confounding.
Results: After adjusting for demographic and comorbidity variables, patients with nicotine dependence undergoing open carpal tunnel release had increased risk of postoperative admission (odds ratio [OR] = 3.1, 95% confidence interval [CI] = 1.6-5.9), ED visit (OR = 1.2, 95% CI = 1.1-1.4), median nerve injury (OR = 2.0, 95% CI = 1.0-4.7), and superficial infections (OR = 2.2, 95% CI = 1.7-2.8) compared with the endoscopic carpal tunnel release cohort.
Conclusion: Patients with nicotine dependence who undergo open carpal tunnel release experience higher 90-day perioperative complication rates compared with those receiving endoscopic carpal tunnel release. This effect persisted in both unmatched and matched analyses, suggesting an endoscopic technique may be preferable in patients with nicotine dependence due to lower short-term complication risk.
背景:腕管释放的最佳手术策略仍然是一个有争议的主题。本研究比较了内窥镜和开放式腕管释放术治疗尼古丁依赖患者腕管综合征的围手术期并发症发生率。方法:查询TriNetX数据库进行回顾性队列研究,共对尼古丁依赖患者进行了22 435例切开腕管松解术和4947例内镜腕管松解术。评估两个队列的短期90天并发症发生率,包括住院、术后急诊就诊、感染、神经损伤、肾损伤和血栓事件。进行倾向评分匹配分析以降低混杂的风险。结果:在调整了人口统计学和合并症变量后,与内窥镜腕管释放组相比,接受开放式腕管释放的尼古丁依赖患者术后入院(优势比[OR] = 3.1, 95%可信区间[CI] = 1.6-5.9)、ED就诊(OR = 1.2, 95% CI = 1.1-1.4)、中神经损伤(OR = 2.0, 95% CI = 1.0-4.7)和表面感染(OR = 2.2, 95% CI = 1.7-2.8)的风险增加。结论:尼古丁依赖患者行切开腕管释放术与行内窥镜腕管释放术相比,90天围手术期并发症发生率更高。这种效果在未匹配和匹配的分析中都存在,表明内窥镜技术可能更适合尼古丁依赖患者,因为其短期并发症风险较低。
{"title":"Improved Outcomes With Endoscopic Carpal Tunnel Release for Patients With Nicotine Dependence.","authors":"Jeffrey Coombs, Christopher M Dussik, Amy Phan, Joseph Ferraro, Danielle Wilbur, Constantinos Ketonis","doi":"10.1177/15589447251415393","DOIUrl":"10.1177/15589447251415393","url":null,"abstract":"<p><strong>Background: </strong>The optimal surgical strategy for carpal tunnel release remains a subject of debate. This study compared the perioperative complication rates of endoscopic and open carpal tunnel release for the treatment of carpal tunnel syndrome in patients with nicotine dependence.</p><p><strong>Methods: </strong>The TriNetX database was queried to conduct a retrospective cohort study, identifying a total of 22 435 open carpal tunnel releases and 4947 endoscopic carpal tunnel releases performed on patients with nicotine dependence. Short-term, 90-day complication rates were assessed across both cohorts, including hospital admissions, postoperative emergency department (ED) visits, infections, nerve injury, renal injury, and thrombotic events. Propensity score-matched analyses were performed to mitigate the risk of confounding.</p><p><strong>Results: </strong>After adjusting for demographic and comorbidity variables, patients with nicotine dependence undergoing open carpal tunnel release had increased risk of postoperative admission (odds ratio [OR] = 3.1, 95% confidence interval [CI] = 1.6-5.9), ED visit (OR = 1.2, 95% CI = 1.1-1.4), median nerve injury (OR = 2.0, 95% CI = 1.0-4.7), and superficial infections (OR = 2.2, 95% CI = 1.7-2.8) compared with the endoscopic carpal tunnel release cohort.</p><p><strong>Conclusion: </strong>Patients with nicotine dependence who undergo open carpal tunnel release experience higher 90-day perioperative complication rates compared with those receiving endoscopic carpal tunnel release. This effect persisted in both unmatched and matched analyses, suggesting an endoscopic technique may be preferable in patients with nicotine dependence due to lower short-term complication risk.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447251415393"},"PeriodicalIF":1.8,"publicationDate":"2026-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12885957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}