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Case Report: A Rare Presentation of Giant Multicompartmental Lipoma of Hand in a 3-Year-Old Child. 病例报告:一例罕见的3岁儿童巨大多室脂肪瘤。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-10 DOI: 10.1177/15589447261422487
Shreyas Gadgil, Rohit Babu Mula, Sreechand Yenuganti, Seetu Palo

Lipomas of the hand are uncommon accounting for only 1% to 3.8% of benign tumors of the hand. Moreover, in children, lipomas of the hand are extremely rare. A giant lipoma, ie, measuring greater than 5 cm, of the hand in the pediatric population is exceptionally uncommon. Lipomas of the hand can often be intermuscular, involving multiple compartments of the hand, presenting as an "infiltrating lipoma." Lipoma of the hand presents as a swelling with variable accompanying symptoms such as restricted movements and neurological complaints depending upon their size and site. Here, we discuss the presentation of a rare case of a giant, infiltrating lipoma in the hand of a 3-year-old child, its diagnosis and management.

手部脂肪瘤并不常见,仅占手部良性肿瘤的1% ~ 3.8%。此外,在儿童中,手部的脂肪瘤极为罕见。一个巨大的脂肪瘤,即测量大于5厘米,在儿科人群中是非常罕见的。手部脂肪瘤常发生于肌肉间,累及手部多个隔室,表现为“浸润性脂肪瘤”。手部脂肪瘤表现为肿胀,伴随各种症状,如运动受限和神经系统疾病,取决于其大小和部位。在这里,我们讨论一个罕见的病例,一个巨大的,浸润性脂肪瘤在一个3岁的孩子的手,其诊断和处理。
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引用次数: 0
Syndactyly and Risk of Cancer. 并趾与癌症风险。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-09 DOI: 10.1177/15589447261416115
Kira L Smith, Matthew V Abola, Logan M Good, Raymond W Liu, Apurva S Shah, Samir K Trehan, Aaron Daluiski

Background: Syndactyly is the most common upper-extremity congenital condition, and cases can be associated with genetic syndromes or arise sporadically (nonsyndromic). The purpose of this investigation was to determine rates of both malignant and benign neoplasms among pediatric patients diagnosed with nonsyndromic syndactyly compared to matched controls.

Methods: The TriNetX US Collaborative database was queried using International Classification of Disease, 10th Revision codes to identify patients aged 10 years or younger diagnosed with syndactyly. Patient history of syndactyly was utilized to categorize patients into 2 cohorts. These cohorts were propensity-matched by age, sex, race, ethnicity, and congenital malformation syndromes. Subsequent rate of neoplasms was compared between patients with and without syndactyly.

Results: A total of 7478 patients aged 10 years or younger diagnosed with syndactyly were identified. After 1:1 propensity matching, both cohorts included 5461 patients. The rate of digestive malignancies was significantly higher int he syndactyly cohort than that in the control cohort. The rate of benign neoplasms was significant at >5 years follow-up duration (P = .016, 95% CI 0.001-0.005) but was not significant at 1 year or 1 to 5 years. Similarly, rate of any neoplasm was significant at >5 years follow-up duration (P = .013, 95% CI 0.001-0.005) but not at 1 year or 1 to 5 years.

Conclusions: Nonsyndromic syndactyly is associated with an increased rate of benign neoplasms and digestive malignancies. Further investigation is needed to better understand the relationship between the syndactyly phenotype and risk of malignancy.

背景:并指畸形是最常见的上肢先天性疾病,病例可与遗传综合征相关或零星发生(非综合征性)。本研究的目的是确定在诊断为无综合征并指畸形的儿童患者中,与匹配的对照组相比,恶性和良性肿瘤的发生率。方法:使用国际疾病分类第10版代码查询TriNetX美国协作数据库,识别10岁及以下诊断为并指畸形的患者。并指病史将患者分为两组。这些队列按年龄、性别、种族、民族和先天性畸形综合征进行倾向匹配。比较有无并指畸形患者的肿瘤发生率。结果:共发现7478例10岁及以下诊断为并指畸形的患者。在1:1倾向匹配后,两个队列均包括5461例患者。并指组消化道恶性肿瘤发生率明显高于对照组。在随访50 ~ 5年时,良性肿瘤的发生率有显著性差异(P = 0.016, 95% CI 0.001 ~ 0.005),但在随访1年或1 ~ 5年时无显著性差异。同样,任何肿瘤的发生率在50 ~ 5年随访期间均有显著性差异(P = 0.013, 95% CI 0.001 ~ 0.005),但在1年或1 ~ 5年随访期间无显著性差异。结论:非综合征性并趾与良性肿瘤和消化道恶性肿瘤的发生率增加有关。需要进一步的研究来更好地了解并指表型与恶性肿瘤风险之间的关系。
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引用次数: 0
Survivorship and Patient Satisfaction With Stablyx Implant for Thumb Carpometacarpal Arthroplasty. 拇指腕掌关节置换术中Stablyx植入物的存活率和患者满意度。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-05 DOI: 10.1177/15589447261422505
Camden O Novikova, Kelsey M Gray, Nicholas J Peterman, Miles C Farlow, Micheala I McCarthy, Anthony E Capito, Peter J Apel

Background: Many surgical techniques and devices are available to address thumb carpometacarpal (CMC) joint arthritis. To date, limited evidence exists regarding patient satisfaction, patient-reported outcomes, and revision-free survivorship of the Stablyx implant. We sought to examine these metrics for these implants against conventional CMC arthroplasty techniques.

Methods: Six hundred and thirty-one patients who underwent CMC arthroplasty were identified at our institution. Patients were contacted to obtain patient satisfaction scores, Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) scores, and potential revision dates. Retrospective chart review was then performed on all 287 respondents. Respondents were placed into cohorts based on the arthroplasty surgical technique: (1) Stablyx (n = 53); (2) ligament reconstruction and tendon interposition (LRTI) with the flexor carpi radialis (n = 90); (3) abductor pollicis longus (APL) suspensionplasty (n = 71); and (4) TightRope suspensionplasty (n = 73). Minimum follow-up was 6 months with an average follow-up of 3.6 ± 2.2 years for the Stablyx cohort and 5.3 ± 2.8 years for all other CMC arthroplasty techniques (AOCAT). Patient demographics, including age, sex, smoking status, Eaton score, and operating surgeon, were also examined.

Results: Through multivariable modeling, higher revision rates were observed in patients who received Stablyx than those who underwent LRTI (control), APL suspensionplasty, or TightRope suspensionplasty. Dissatisfaction was greater in the Stablyx cohort (35%) than the AOCAT cohort (6.8%). No difference in QuickDASH scores were observed between groups.

Conclusions: Higher revision rates and lower patient satisfaction scores were seen in patients who underwent Stablyx CMC hemiarthroplasty compared with other arthroplasty techniques.

背景:许多外科技术和设备可用于解决拇指腕掌关节关节炎。迄今为止,关于患者满意度、患者报告的结果和Stablyx植入物的无修改生存期的证据有限。我们试图检查这些植入物与传统CMC关节置换术的指标。方法:631例在我院行CMC关节置换术的患者。联系患者以获得患者满意度评分、手臂、肩膀和手的快速残疾(QuickDASH)评分和可能的修订日期。然后对所有287名受访者进行回顾性图表审查。根据关节成形术的技术将应答者分组:(1)Stablyx (n = 53);(2)桡侧腕屈肌韧带重建和肌腱插入(LRTI) (n = 90);(3)拇长外展肌(APL)悬吊成形术(71例);(4)钢丝绳悬吊成形术(n = 73)。Stablyx组的最短随访时间为6个月,平均随访时间为3.6±2.2年,其他CMC关节置换技术(AOCAT)的平均随访时间为5.3±2.8年。患者的人口统计资料,包括年龄、性别、吸烟状况、伊顿评分和手术医生,也被检查。结果:通过多变量建模,观察到接受Stablyx的患者比接受LRTI(对照组)、APL悬吊成形术或TightRope悬吊成形术的患者翻修率更高。Stablyx组的不满意度(35%)高于AOCAT组(6.8%)。各组之间QuickDASH评分无差异。结论:与其他关节置换术相比,采用稳定CMC半关节置换术的患者翻修率较高,患者满意度较低。
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引用次数: 0
Ambulatory Free Medial Femoral Condyle and Trochlea Flaps for Management of Scaphoid Fractures and Nonunions. 可移动股骨内侧髁和滑车皮瓣治疗舟状骨骨折和骨不连。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-04 DOI: 10.1177/15589447261422499
Benjamin A Sarac, Hisham M Awan, Ryan W Schmucker

Background: Fractures of the scaphoid are the most common carpal bone fracture and have high rates of nonunion. Management of nonunions is crucial to preventing the predictable pattern of arthritis seen with scaphoid nonunion advanced collapse (SNAC). The medial femoral condyle (MFC) and trochlea (MFT) flaps have become a popular option for the management of recalcitrant nonunions. We analyzed our experience with outpatient free vascuarlized MFC/MFT flaps for management of scaphoid fractures and nonunions.

Methods: A retrospective review of a 2-surgeon approach to outpatient MFC/MFT flap reconstruction of scaphoid nonunions without postoperative flap monitoring was performed. Baseline demographic details, injury history, preoperative and postoperative radiographic analysis, operative details, and postoperative union were collected. Patients were discharged either on the day of surgery or the follow morning.

Results: Ten patients met inclusion criteria. Four patients had involvement of the proximal pole and received an MFT as opposed to an MFC. Eight patients were discharged on the day of surgery, and the remaining 2 were discharged on the first postoperative day. Nine patients (90%) showed postoperative union on imaging, with no residual dorsal intercalated segment instability deformity.

Conclusions: Vascularized bone grafting with a free MFC/MFT for management of recalcitrant scaphoid nonunion can be successfully and safely performed without postoperative monitoring in an outpatient surgery center setting. This series is the first to report on ambulatory free MFC/MFT flap reconstruction, and to our knowledge, it is the second in the literature to describe free vascularized tissue transfer of any kind performed with same-day discharge.

Level of evidence: Level IV, Therapeutic.

背景:舟状骨骨折是最常见的腕骨骨折,且具有较高的不愈合率。骨不连的管理对于预防舟状骨不连晚期塌陷(SNAC)导致的可预测的关节炎模式至关重要。股骨内侧髁(MFC)和滑车(MFT)皮瓣已成为治疗顽固性骨不连的一种流行选择。我们分析了门诊免费血管化MFC/MFT皮瓣治疗舟状骨骨折和骨不连的经验。方法:回顾性分析了2位外科医生在无术后皮瓣监测的情况下对门诊MFC/MFT皮瓣重建舟状骨不连的方法。收集基线人口统计信息、损伤史、术前和术后放射学分析、手术细节和术后愈合。患者在手术当天或第二天早上出院。结果:10例患者符合纳入标准。4例患者有近极受累,接受了MFT而不是MFC。8例患者于手术当日出院,2例患者于术后第一天出院。9例(90%)患者术后影像学显示愈合,无残余背插节段不稳畸形。结论:游离MFC/MFT带血管骨移植治疗顽固性舟状骨不连在门诊手术中心可成功且安全地进行,无需术后监测。本系列是第一个关于动态游离MFC/MFT皮瓣重建的报道,据我们所知,这是文献中第二个描述当日出院的任何类型的游离血管化组织转移的报道。证据等级:四级,治疗性。
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引用次数: 0
ECTR With Tourniquet and Local Anesthesia Only: Efficiency and Patient Satisfaction. 仅止血带和局部麻醉的ECTR:效率和患者满意度。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-04 DOI: 10.1177/15589447261418695
Kasparas Zilinskas, Reena Bakshi, Kristin Clemmons, Melanie Bertolino Zilinskas, Alexander Hoey, Manoucher Lance Tavana
<p><strong>Background: </strong>Carpal tunnel release (CTR) is commonly performed using wide-awake local anesthesia no tourniquet (WALANT) in a clinic or ambulatory surgery center and is shown to have similar satisfaction rates and postoperative complication profile compared to operating room (OR) procedures. Endoscopic carpal tunnel release (ECTR) is commonly performed; however, it is usually done in an OR setting with the use of anesthesia (OR-ECTR). We present a single institution's experience performing ECTR utilizing a tourniquet under local only anesthesia (LO-ECTR). We compared procedural efficiency and environmental impact between OR-ECTR and LO-ECTR. In addition, patient satisfaction with LO-ECTR was assessed via a postprocedural survey.</p><p><strong>Methods: </strong>A retrospective review identified patients who underwent OR-ECTR and LO-ECTR from June 2021 to June 2023 by a single surgeon at our institution. Efficiency was measured by comparing procedure, recovery, and total time spent in the hospital. Environmental impact was assessed by measuring OR waste weight. Student's <i>t</i>-tests for continuous variables and Chi-squared tests for categorical variables were performed. Patients in the LO-ECTR group answered a survey immediately postoperatively that included pain scores on a Likert scale and overall satisfaction. Inclusion criteria included primary carpal tunnel syndrome (CTS), diagnosis based on clinical or electromyography studies, and no concurrent procedures. The Microaire SmartRelease ECTR system was used in the OR-ECTR cases, and the Trice Seg-WAY ECTR-d system was used in the LO-ECTR cases.</p><p><strong>Results: </strong>A total of 137 cases in the LO-ECTR and 104 cases in the OR-ECTR group met inclusion criteria. Age, body mass index, operative hand, and race were similar between both groups. LO-ECTR procedures were faster than OR-ECTR procedures for all time metrics. Total procedure and operating time improved (9 ± 2 minutes vs 14 ± 4 minutes and 15 ± 2 minutes vs 28 ± 6 minutes). Preoperative holding time improved (35 ± 15 minutes vs 89 ± 30 minutes). Recovery time was notably faster (7 ± 4 minutes vs 48 ± 22 minutes), which affected total hospital time (61.9 ± 18.6 minutes vs 166.9 ± 38.3 minutes). All differences were statistically significant with <i>P</i> < .001. Waste weights were significantly lower in the LO-ECTR cohort than those in the OR-ECTR cohort; however, sample sizes were small in both cohorts (1.3 ± 0.04 kg in LO-ECTR vs 6.0 ± 0.7 kg in OR-ECTR, <i>P</i> < .001). Within the LO-ECTR group, the overall pain level experience was mild/moderate. The average overall satisfaction with the experience was 96.6%, with 98.5% of patients stating they would recommend this procedure to a friend.</p><p><strong>Conclusion: </strong>LO-ECTR was faster than OR-ECTR for all studied time metrics. Data are suggestive of improvement in the environmental impact factor. Limitations include a lack of meaningful postoperative
背景:腕管释放术(CTR)通常在临床或门诊手术中心使用全清醒局麻无止血带(WALANT)进行,与手术室(or)手术相比,其满意率和术后并发症发生率相似。内镜下腕管释放术(ECTR)是常用的手术;然而,它通常是在手术室中使用麻醉(OR- ectr)进行的。我们介绍了一家机构在局部麻醉下使用止血带进行ECTR (LO-ECTR)的经验。我们比较了OR-ECTR和LO-ECTR的程序效率和环境影响。此外,通过术后调查评估患者对LO-ECTR的满意度。方法:回顾性分析我院一名外科医生于2021年6月至2023年6月期间接受OR-ECTR和LO-ECTR的患者。效率是通过比较手术、恢复和住院总时间来衡量的。通过测量废物重量来评估环境影响。对连续变量进行学生t检验,对分类变量进行卡方检验。LO-ECTR组的患者术后立即回答了一项调查,包括李克特疼痛评分和总体满意度。纳入标准包括原发性腕管综合征(CTS),诊断基于临床或肌电图研究,无并发手术。在OR-ECTR中使用Microaire SmartRelease ECTR系统,在LO-ECTR中使用Trice Seg-WAY ECTR-d系统。结果:LO-ECTR组137例,OR-ECTR组104例符合纳入标准。两组的年龄、体重指数、手术手和种族相似。在所有时间指标上,LO-ECTR程序都比OR-ECTR程序快。总的程序和手术时间(9±2分钟比14±4分钟和15±2分钟比28±6分钟)有所改善。术前保持时间延长(35±15分钟vs 89±30分钟)。恢复时间明显更快(7±4分钟vs 48±22分钟),影响总住院时间(61.9±18.6分钟vs 166.9±38.3分钟)。差异均有统计学意义,P < 0.001。低- ectr组的废物重量显著低于高- ectr组;然而,两个队列的样本量都很小(低ectr组为1.3±0.04 kg,高ectr组为6.0±0.7 kg, P < 0.001)。在LO-ECTR组中,总体疼痛水平为轻度/中度。平均总体满意度为96.6%,98.5%的患者表示他们会向朋友推荐这种手术。结论:在所有研究的时间指标上,LO-ECTR均快于OR-ECTR。数据表明环境影响因素有所改善。局限性包括缺乏有意义的术后患者事件和研究的回顾性性质。进一步的研究将调查LO-ECTR组的长期结果。
{"title":"ECTR With Tourniquet and Local Anesthesia Only: Efficiency and Patient Satisfaction.","authors":"Kasparas Zilinskas, Reena Bakshi, Kristin Clemmons, Melanie Bertolino Zilinskas, Alexander Hoey, Manoucher Lance Tavana","doi":"10.1177/15589447261418695","DOIUrl":"10.1177/15589447261418695","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Carpal tunnel release (CTR) is commonly performed using wide-awake local anesthesia no tourniquet (WALANT) in a clinic or ambulatory surgery center and is shown to have similar satisfaction rates and postoperative complication profile compared to operating room (OR) procedures. Endoscopic carpal tunnel release (ECTR) is commonly performed; however, it is usually done in an OR setting with the use of anesthesia (OR-ECTR). We present a single institution's experience performing ECTR utilizing a tourniquet under local only anesthesia (LO-ECTR). We compared procedural efficiency and environmental impact between OR-ECTR and LO-ECTR. In addition, patient satisfaction with LO-ECTR was assessed via a postprocedural survey.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective review identified patients who underwent OR-ECTR and LO-ECTR from June 2021 to June 2023 by a single surgeon at our institution. Efficiency was measured by comparing procedure, recovery, and total time spent in the hospital. Environmental impact was assessed by measuring OR waste weight. Student's &lt;i&gt;t&lt;/i&gt;-tests for continuous variables and Chi-squared tests for categorical variables were performed. Patients in the LO-ECTR group answered a survey immediately postoperatively that included pain scores on a Likert scale and overall satisfaction. Inclusion criteria included primary carpal tunnel syndrome (CTS), diagnosis based on clinical or electromyography studies, and no concurrent procedures. The Microaire SmartRelease ECTR system was used in the OR-ECTR cases, and the Trice Seg-WAY ECTR-d system was used in the LO-ECTR cases.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 137 cases in the LO-ECTR and 104 cases in the OR-ECTR group met inclusion criteria. Age, body mass index, operative hand, and race were similar between both groups. LO-ECTR procedures were faster than OR-ECTR procedures for all time metrics. Total procedure and operating time improved (9 ± 2 minutes vs 14 ± 4 minutes and 15 ± 2 minutes vs 28 ± 6 minutes). Preoperative holding time improved (35 ± 15 minutes vs 89 ± 30 minutes). Recovery time was notably faster (7 ± 4 minutes vs 48 ± 22 minutes), which affected total hospital time (61.9 ± 18.6 minutes vs 166.9 ± 38.3 minutes). All differences were statistically significant with &lt;i&gt;P&lt;/i&gt; &lt; .001. Waste weights were significantly lower in the LO-ECTR cohort than those in the OR-ECTR cohort; however, sample sizes were small in both cohorts (1.3 ± 0.04 kg in LO-ECTR vs 6.0 ± 0.7 kg in OR-ECTR, &lt;i&gt;P&lt;/i&gt; &lt; .001). Within the LO-ECTR group, the overall pain level experience was mild/moderate. The average overall satisfaction with the experience was 96.6%, with 98.5% of patients stating they would recommend this procedure to a friend.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;LO-ECTR was faster than OR-ECTR for all studied time metrics. Data are suggestive of improvement in the environmental impact factor. Limitations include a lack of meaningful postoperative ","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"15589447261418695"},"PeriodicalIF":1.8,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147354738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine Learning-Aided Diagnosis Enhances Human Detection of Perilunate Dislocations. 机器学习辅助诊断增强了人类对月骨周围脱位的检测。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2025-01-15 DOI: 10.1177/15589447241308603
Anna Luan, Lisa von Rabenau, Arman T Serebrakian, Christopher S Crowe, Bao H Do, Kyle R Eberlin, James Chang, Brian C Pridgen

Background: Perilunate/lunate injuries are frequently misdiagnosed. We hypothesize that utilization of a machine learning algorithm can improve human detection of perilunate/lunate dislocations.

Methods: Participants from emergency medicine, hand surgery, and radiology were asked to evaluate 30 lateral wrist radiographs for the presence of a perilunate/lunate dislocation with and without the use of a machine learning algorithm, which was used to label the lunate. Human performance with and without the machine learning tool was evaluated using sensitivity, specificity, accuracy, and F1 score.

Results: A total of 137 participants were recruited, with 55 respondents from emergency medicine, 33 from radiology, and 49 from hand surgery. Thirty-nine participants were attending physicians or fellows, and 98 were residents. Use of the machine learning tool improved specificity from 88% to 94%, accuracy from 89% to 93%, and F1 score from 0.89 to 0.92. When stratified by training level, attending physicians and fellows had an improvement in specificity from 93% to 97%. For residents, use of the machine learning tool resulted in improved accuracy from 86% to 91% and specificity from 86% to 93%. The performance of surgery and radiology residents improved when assisted by the tool to achieve similar accuracy to attendings, and their assisted diagnostic performance reaches levels similar to that of the fully automated artificial intelligence tool.

Conclusions: Use of a machine learning tool improves resident accuracy for radiographic detection of perilunate dislocations, and improves specificity for all training levels. This may help to decrease misdiagnosis of perilunate dislocations, particularly when subspecialist evaluation is delayed.

背景:月骨周围/月骨损伤经常被误诊。我们假设利用机器学习算法可以提高人类对月骨周围/月骨脱位的检测。方法:来自急诊医学、手外科和放射学的参与者被要求评估30张侧位腕关节x线片是否存在月骨周围/月骨脱位,有无使用机器学习算法,该算法用于标记月骨。使用和不使用机器学习工具评估人类的表现,使用敏感性、特异性、准确性和F1评分。结果:共招募了137名参与者,其中55名来自急诊医学,33名来自放射学,49名来自手外科。39名参与者是主治医生或研究员,98名是住院医生。使用机器学习工具将特异性从88%提高到94%,准确性从89%提高到93%,F1评分从0.89提高到0.92。当按培训水平分层时,主治医生和研究员的特异性从93%提高到97%。对于住院医生来说,使用机器学习工具将准确率从86%提高到91%,特异性从86%提高到93%。在该工具的帮助下,外科和放射科住院医生的表现得到了改善,达到了与主治医生相似的准确性,他们的辅助诊断性能达到了与全自动人工智能工具相似的水平。结论:机器学习工具的使用提高了月骨周围脱位放射学检测的准确性,并提高了所有训练水平的特异性。这可能有助于减少月骨周围脱位的误诊,特别是当专科评估延迟时。
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引用次数: 0
Aggressive Digital Papillary Adenocarcinoma: A Meta-Analysis of the Presentation, Treatment, and Outcomes of a Rare Hand Tumor. 侵袭性手指乳头状腺癌:一项罕见手部肿瘤的表现、治疗和结果的荟萃分析。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2025-01-10 DOI: 10.1177/15589447241308612
Shaun D Mendenhall, Emily M Graham, Natasha N Lewis, Ryan W Schmucker, Jacob P Veith, Jennifer L Koechle, Michael W Neumeister

Background: Aggressive digital papillary adenocarcinoma (ADPA) is a rare skin adnexal tumor with a predilection for the hand. The presentation, treatment, and outcomes of ADPA remain poorly defined due to the scarcity of reports and low-level evidence of published findings.

Methods: We performed a meta-analysis following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines with the intent to provide hand surgeons a better understanding of the diagnosis and treatment of the disease. Three additional cases of ADPA from our institution were combined with the results from the systematic review.

Results: A total of 238 cases were included in the meta-analysis. Most ADPAs were painful, evolving, and less than 2 cm in size. Regional sentinel lymph node biopsies were performed in 55 patients, of which 25.5% were positive. Overall cohort recurrence and distant metastasis rates were 24.3% and 18.1%, respectively. Patients who obtained clear margins within 6 months of diagnosis had significantly lower rates of recurrence, metastasis, and mortality (P < .001, P = .04, P = .003, respectively). There were no differences in recurrence or metastasis rates in those who obtained clear margins by excision or amputation (P = .27 and P = .07, respectively). In patients who died from disease (6.0%), 5.0 years was the average time to death.

Conclusions: Aggressive digital papillary adenocarcinoma should be included in the differential diagnosis of hand lesions with unusual presentations or lack of response to other therapies. Clear margins should be obtained within 6 months of diagnosis, and routine surveillance should be provided by an oncologic physician familiar with ADPA as these tumors have high recurrence rates.

背景:侵袭性手指乳头状腺癌(ADPA)是一种罕见的皮肤附件肿瘤,多发生于手部。由于报告的缺乏和已发表的研究结果的低水平证据,ADPA的表现、治疗和结果仍然不明确。方法:我们根据系统评价和meta分析指南的首选报告项目进行了荟萃分析,目的是让手外科医生更好地了解该疾病的诊断和治疗。我们将我院另外三例ADPA病例与系统评价的结果相结合。结果:meta分析共纳入238例。大多数adpa是痛苦的,不断发展的,尺寸小于2厘米。55例患者行局部前哨淋巴结活检,其中25.5%为阳性。总体队列复发率和远处转移率分别为24.3%和18.1%。诊断后6个月内切缘清晰的患者复发、转移和死亡率明显降低(P < 0.001, P = 0.04, P = 0.003)。在切除或截肢获得清晰边缘的患者中,复发或转移率无差异(P = 0.27和P = 0.07)。在疾病死亡的患者中(6.0%),平均死亡时间为5.0年。结论:侵袭性手指乳头状腺癌应纳入异常表现或对其他治疗缺乏反应的手部病变的鉴别诊断。由于这些肿瘤复发率高,应在诊断后6个月内明确界限,并由熟悉ADPA的肿瘤科医生进行常规监测。
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引用次数: 0
Understanding Stakeholder Priorities in Dupuytren Disease: A Qualitative Study. 理解Dupuytren病的利益相关者优先级:一项定性研究。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2024-12-27 DOI: 10.1177/15589447241306143
Marta Karpinski, Caroline Hircock, Lucas Gallo, Emily Dunn, Jessica Murphy, Manraj N Kaur, Achilles Thoma

Background: Currently, there is no recommended standard set of outcomes to report in Dupuytren disease treatment studies, nor are there guidelines on how the outcomes themselves should be reported. This study aimed to elicit the most salient issues for patients living with and undergoing treatment for Dupuytren disease, as well as for the hand surgeons, occupational therapists, and physical therapists caring for these patients.

Methods: A qualitative, interpretive description study employing one-on-one semi-structured interviews was conducted. Ten surgeons, 12 occupational and physical therapists, and 10 patients were interviewed.

Results: Priorities related to Dupuytren disease treatment and recovery differed by stakeholder group. Surgeons prioritized range of motion, recovery time, and recurrence. Physical and occupational therapists frequently mentioned range of motion, grip strength, activities of daily living, return to meaningful activities, wound healing, edema, lack of sensation, and pain as important treatment outcomes. Patients described extension deficit, activities of daily living, holding objects, and lack of sensation.

Conclusions: Through the present study, we have identified outcomes of high importance to patients, hand surgeons, occupational therapists, and physical therapists. These results can be used to inform the development of a core outcome set for Dupuytren contracture.

背景:目前,没有推荐的Dupuytren病治疗研究报告结果的标准集,也没有关于如何报告结果本身的指南。本研究旨在为患有和正在接受Dupuytren病治疗的患者以及护理这些患者的手外科医生、职业治疗师和物理治疗师引出最突出的问题。方法:采用一对一半结构化访谈进行定性、解释性描述研究。访谈了10名外科医生、12名职业理疗师和10名患者。结果:不同利益相关者群体对Dupuytren病治疗和康复的优先级不同。外科医生优先考虑活动范围、恢复时间和复发率。物理和职业治疗师经常提到运动范围、握力、日常生活活动、恢复有意义的活动、伤口愈合、水肿、感觉缺乏和疼痛是重要的治疗结果。患者描述伸展缺陷,日常生活活动,拿东西,缺乏感觉。结论:通过本研究,我们确定了对患者、手外科医生、职业治疗师和物理治疗师非常重要的结果。这些结果可用于制定Dupuytren挛缩的核心结果集。
{"title":"Understanding Stakeholder Priorities in Dupuytren Disease: A Qualitative Study.","authors":"Marta Karpinski, Caroline Hircock, Lucas Gallo, Emily Dunn, Jessica Murphy, Manraj N Kaur, Achilles Thoma","doi":"10.1177/15589447241306143","DOIUrl":"10.1177/15589447241306143","url":null,"abstract":"<p><strong>Background: </strong>Currently, there is no recommended standard set of outcomes to report in Dupuytren disease treatment studies, nor are there guidelines on how the outcomes themselves should be reported. This study aimed to elicit the most salient issues for patients living with and undergoing treatment for Dupuytren disease, as well as for the hand surgeons, occupational therapists, and physical therapists caring for these patients.</p><p><strong>Methods: </strong>A qualitative, interpretive description study employing one-on-one semi-structured interviews was conducted. Ten surgeons, 12 occupational and physical therapists, and 10 patients were interviewed.</p><p><strong>Results: </strong>Priorities related to Dupuytren disease treatment and recovery differed by stakeholder group. Surgeons prioritized range of motion, recovery time, and recurrence. Physical and occupational therapists frequently mentioned range of motion, grip strength, activities of daily living, return to meaningful activities, wound healing, edema, lack of sensation, and pain as important treatment outcomes. Patients described extension deficit, activities of daily living, holding objects, and lack of sensation.</p><p><strong>Conclusions: </strong>Through the present study, we have identified outcomes of high importance to patients, hand surgeons, occupational therapists, and physical therapists. These results can be used to inform the development of a core outcome set for Dupuytren contracture.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"472-477"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancellous Grafting Versus Corticocancellous Graft With Volar Locked Plating for Scaphoid Waist Fracture Nonunion: An Evaluation of Early Bony Bridging. 松质骨移植与皮质松质骨移植并发掌侧锁定钢板治疗舟状骨腰部骨折不愈合:早期骨桥的评估。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2024-12-27 DOI: 10.1177/15589447241308598
Michael J Stoltz, James Gainer, John A Nyland, Victor L Fehrenbacher, Amit Gupta, Luke P Robinson

Background: Achieving bony union in scaphoid nonunion fractures is challenging. Various bone grafts have been studied using headless compression screws (HCS) fixation. However, the impact of bone graft choice on bone healing with volar locking plates (VLP) use is less clear. This study evaluates osseous bridging using packed cancellous grafting versus corticocancellous grafting when used during scaphoid waist nonunion repair with volar plating.

Methods: A retrospective case series was performed of 22 consecutive patients with a scaphoid waist fracture nonunions that were treated with VLP fixation and bone autografts. Inclusion criteria required ≥90-day follow-up clinical examination and postoperative computed tomography (CT) scan. Graft types included corticocancellous or packed cancellous autograft harvested from the radius or iliac crest. Amount of bone healing and presence of residual dorsal intercalated segmental instability were determined by 3 fellowship-trained hand surgeons.

Results: Twenty-two patients with scaphoid fracture nonunions that met study inclusion criteria were evaluated. Postoperative CT scan showed osseous bridging in 95% (21/22) of patients. Despite less time between surgery and the final follow-up CT scan (102.7 ± 59 days for packed cancellous autografts vs 133.6 ± 73 days for corticocancellous autografts), the packed cancellous autograft group displayed higher osseous bridging percentages compared with the corticocancellous graft (80.7% ± 17% vs 47.8% ± 35%, P = .013).

Conclusion: Nearly all patients displayed osseous bridging on postoperative CT scan with VLP and autograft use. However, study findings suggest that packed cancellous autograft use displayed more robust early healing.

背景:在舟状骨不愈合骨折中实现骨愈合是具有挑战性的。使用无头加压螺钉(HCS)固定研究了各种骨移植物。然而,骨移植选择对掌侧锁定钢板(VLP)骨愈合的影响尚不清楚。本研究评估了掌侧钢板修复舟状骨腰骨不连时采用填充松质骨移植与皮质松质骨移植的骨桥。方法:对22例连续行VLP固定和自体骨移植治疗的舟状骨腰骨折不连患者进行回顾性分析。纳入标准要求随访≥90天临床检查和术后CT扫描。移植物类型包括从桡骨或髂骨取的皮质松质或填充松质自体移植物。骨愈合量和残余背侧插入节段不稳定的存在由3名研究员培训的手外科医生确定。结果:22例舟状骨骨折不连符合研究纳入标准。术后CT扫描显示95%(21/22)患者出现骨桥。尽管从手术到最终随访CT扫描之间的时间较短(填充松质自体移植物为102.7±59天,皮质松质自体移植物为133.6±73天),但与皮质松质自体移植物相比,填充松质自体移植物组显示出更高的骨桥率(80.7%±17%比47.8%±35%,P = 0.013)。结论:VLP和自体移植物术后CT扫描显示骨桥。然而,研究结果表明,使用填充的自体松质移植物显示出更强健的早期愈合。
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引用次数: 0
Effect of Time to Surgery on Surgical Site Infection in Open Distal Radius Fractures: A Review of the ACS Trauma Quality Improvement Program Database. 手术时间对开放性桡骨远端骨折手术部位感染的影响:对ACS创伤质量改善计划数据库的回顾
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2024-12-25 DOI: 10.1177/15589447241305422
Walter Sobba, Lawrence J Lin, Gerardo E Sanchez-Navarro, Jadie De Tolla, Omri Ayalon, Jacques H Hacquebord

Background: Managing open distal radius fractures (DRFs) poses challenges. While preventing surgical site infection (SSI) involves prompt antibiotic administration and thorough irrigation and debridement, the impact of urgent intervention on reducing postoperative infection rates is debated. We hypothesize that timing of surgery does not significantly affect the incidence of SSI in open DRF treated within or after 24 hours from time of injury.

Methods: We retrospectively analyzed the American College of Surgeons Trauma Quality Improvement Program from 2011 to 2021. We focused on outcome variables, including superficial SSI and deep SSI or osteomyelitis. To evaluate the relationship between time to operative intervention and SSI rates, we employed least absolute shrinkage and selection operator and multivariate regression models, adjusting for patient-specific factors and injury severity.

Results: A total of 14 486 patients were included. Regression modeling demonstrated a 23% increase in the odds of deep SSI with each 1-day delay in surgery (P = .010). However, no association was found between time to surgery and superficial SSI (odds ratio [OR] = 0.96, P = .768). Injury severity score (ISS) was associated with increased odds of superficial SSI (OR = 1.06, P < .001) and deep SSI (OR = 1.06, P < .001) while diabetes (OR = 3.56, P = .013) was significantly associated with increased rates of superficial SSI.

Conclusions: Extended time to surgery correlates with a modest rise in deep SSI incidence in open DRF. However, there was no heightened risk of superficial SSI in patients with delayed surgery. Polytrauma, alcohol use disorder, and diabetes were linked to elevated SSI rates in open DRF.

导言:桡骨远端开放性骨折(DRFs)的治疗面临挑战。虽然预防手术部位感染(SSI)涉及及时使用抗生素和彻底冲洗和清创,但紧急干预对降低术后感染率的影响仍存在争议。我们假设手术时间对开放性DRF在受伤后24小时内或24小时后治疗的SSI发生率没有显著影响。方法:回顾性分析2011年至2021年美国外科医师学会创伤质量改善项目。我们关注结果变量,包括浅表SSI和深部SSI或骨髓炎。为了评估手术干预时间与SSI发生率之间的关系,我们采用了最小绝对收缩和选择算子和多元回归模型,调整了患者特定因素和损伤严重程度。结果:共纳入14 486例患者。回归模型显示,手术每延迟1天,发生深部SSI的几率增加23% (P = 0.010)。然而,手术时间与浅表SSI之间没有关联(优势比[OR] = 0.96, P = .768)。损伤严重程度评分(ISS)与浅表SSI (OR = 1.06, P < .001)和深部SSI (OR = 1.06, P < .001)的发生率增加相关,而糖尿病(OR = 3.56, P = .013)与浅表SSI发生率增加显著相关。结论:延长手术时间与开放性DRF深部SSI发生率适度上升相关。然而,延迟手术患者发生浅表SSI的风险没有增加。多发创伤、酒精使用障碍和糖尿病与开放性DRF中SSI发生率升高有关。
{"title":"Effect of Time to Surgery on Surgical Site Infection in Open Distal Radius Fractures: A Review of the ACS Trauma Quality Improvement Program Database.","authors":"Walter Sobba, Lawrence J Lin, Gerardo E Sanchez-Navarro, Jadie De Tolla, Omri Ayalon, Jacques H Hacquebord","doi":"10.1177/15589447241305422","DOIUrl":"10.1177/15589447241305422","url":null,"abstract":"<p><strong>Background: </strong>Managing open distal radius fractures (DRFs) poses challenges. While preventing surgical site infection (SSI) involves prompt antibiotic administration and thorough irrigation and debridement, the impact of urgent intervention on reducing postoperative infection rates is debated. We hypothesize that timing of surgery does not significantly affect the incidence of SSI in open DRF treated within or after 24 hours from time of injury.</p><p><strong>Methods: </strong>We retrospectively analyzed the American College of Surgeons Trauma Quality Improvement Program from 2011 to 2021. We focused on outcome variables, including superficial SSI and deep SSI or osteomyelitis. To evaluate the relationship between time to operative intervention and SSI rates, we employed least absolute shrinkage and selection operator and multivariate regression models, adjusting for patient-specific factors and injury severity.</p><p><strong>Results: </strong>A total of 14 486 patients were included. Regression modeling demonstrated a 23% increase in the odds of deep SSI with each 1-day delay in surgery (<i>P</i> = .010). However, no association was found between time to surgery and superficial SSI (odds ratio [OR] = 0.96, <i>P</i> = .768). Injury severity score (ISS) was associated with increased odds of superficial SSI (OR = 1.06, <i>P</i> < .001) and deep SSI (OR = 1.06, <i>P</i> < .001) while diabetes (OR = 3.56, <i>P</i> = .013) was significantly associated with increased rates of superficial SSI.</p><p><strong>Conclusions: </strong>Extended time to surgery correlates with a modest rise in deep SSI incidence in open DRF. However, there was no heightened risk of superficial SSI in patients with delayed surgery. Polytrauma, alcohol use disorder, and diabetes were linked to elevated SSI rates in open DRF.</p>","PeriodicalId":12902,"journal":{"name":"HAND","volume":" ","pages":"358-364"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11669146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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