Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25854
G. Bhattarai
Amaranth (Amaranthus), a member of amaranthaceous group of plants, is classified as a pseudo cereal and grown either as a grain crop or as a leafy vegetable. It is one of the few multi-purpose crops which can supply grains and tasty leafy vegetables. The grain has ability to grow in the dry and semi-dry lands due to its drought tolerant characteristics. It is rich in protein, lysine, carotenoids, dietary fiber, iron, vitamin C, vitamin A, riboflavin, thiamin, folic acid, calcium etc. Amaranth contain substantial amount of bioactive components such as tocopherol (α, β and γ), DPPH (2, 2-diphenyl-1-picrylhydrazyl), anthocyanins, lutein and other phenolic compounds. The fat in amaranth seed is low but composed of essential fatty acids (linoleic and linolenic). Grain amaranth can be used as a flour ingredient for pancakes, bread, muffins, dumplings, crackers, cookies, puddings, porridge, cakes and as a roasted puffed snack. Vegetable types amaranth (also leaves of grain amaranth) are used to make curry, vegetable salads, steamed salad, boiled soups, stir fried, or baked to taste. The seeds and leaves of amaranth are used as herbal remedies and have nutraceutical value. Because of no gluten content, grain amaranth is valuable carbohydrate source for person having glutin intolerance problem. Seed or leaf of amaranths contains some antinutritional factors, such as saponins, tannins, phytic acid, oxalates, protease inhibitors, nitrates and phytohemagglutinins. Thermal processing in moist environment, prior to food use inactivates the antinutritional factors. The present paper briefly describes crop introduction, botany, chemical and nutritive composition, functional and bioactive components, antinutritional factors and food uses including new findings on functional properties of grain amaranth.
{"title":"Amaranth: A Golden Crop for Future","authors":"G. Bhattarai","doi":"10.3126/hijost.v2i0.25854","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25854","url":null,"abstract":"Amaranth (Amaranthus), a member of amaranthaceous group of plants, is classified as a pseudo cereal and grown either as a grain crop or as a leafy vegetable. It is one of the few multi-purpose crops which can supply grains and tasty leafy vegetables. The grain has ability to grow in the dry and semi-dry lands due to its drought tolerant characteristics. It is rich in protein, lysine, carotenoids, dietary fiber, iron, vitamin C, vitamin A, riboflavin, thiamin, folic acid, calcium etc. Amaranth contain substantial amount of bioactive components such as tocopherol (α, β and γ), DPPH (2, 2-diphenyl-1-picrylhydrazyl), anthocyanins, lutein and other phenolic compounds. The fat in amaranth seed is low but composed of essential fatty acids (linoleic and linolenic). Grain amaranth can be used as a flour ingredient for pancakes, bread, muffins, dumplings, crackers, cookies, puddings, porridge, cakes and as a roasted puffed snack. Vegetable types amaranth (also leaves of grain amaranth) are used to make curry, vegetable salads, steamed salad, boiled soups, stir fried, or baked to taste. The seeds and leaves of amaranth are used as herbal remedies and have nutraceutical value. Because of no gluten content, grain amaranth is valuable carbohydrate source for person having glutin intolerance problem. Seed or leaf of amaranths contains some antinutritional factors, such as saponins, tannins, phytic acid, oxalates, protease inhibitors, nitrates and phytohemagglutinins. Thermal processing in moist environment, prior to food use inactivates the antinutritional factors. The present paper briefly describes crop introduction, botany, chemical and nutritive composition, functional and bioactive components, antinutritional factors and food uses including new findings on functional properties of grain amaranth.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89416681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25853
S. Shrestha, R. Yadav
Soy corn yoghurt is a vegan friendly product prepared by using soymilk as the major ingredient. The aim of this study was to assess the effect of corn milk addition (0, 10, 20, 25 & 30%) on the quality of soy yoghurt. The samples were subjected to sensory evaluation for consumer acceptability and data were subjected to statistical analysis. From sensory evaluation and statistical analysis 10% corn milk inclusion was selected as the best product (p<0.05). The yoghurt thus prepared using 10% corn milk had total solids 22.04%, moisture content 78.62%, protein 4.84%, fat 3.29%, carbohydrate 12.57%, ash 0.81%, acidity 0.68% and pH 4.58. Both control and 10% corn milk incorporated yoghurts were stored under refrigeration 6±1° C and analyzed at 2 days interval till 10 days. Yoghurts with corn milk and control were organoleptically acceptable up to 10 and 6 days respectively. Acidity and syneresis increased but pH decreased with storage time in both samples.
{"title":"Preparation and Quality Evaluation of Soy Corn Yoghurt","authors":"S. Shrestha, R. Yadav","doi":"10.3126/hijost.v2i0.25853","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25853","url":null,"abstract":"Soy corn yoghurt is a vegan friendly product prepared by using soymilk as the major ingredient. The aim of this study was to assess the effect of corn milk addition (0, 10, 20, 25 & 30%) on the quality of soy yoghurt. The samples were subjected to sensory evaluation for consumer acceptability and data were subjected to statistical analysis. From sensory evaluation and statistical analysis 10% corn milk inclusion was selected as the best product (p<0.05). The yoghurt thus prepared using 10% corn milk had total solids 22.04%, moisture content 78.62%, protein 4.84%, fat 3.29%, carbohydrate 12.57%, ash 0.81%, acidity 0.68% and pH 4.58. Both control and 10% corn milk incorporated yoghurts were stored under refrigeration 6±1° C and analyzed at 2 days interval till 10 days. Yoghurts with corn milk and control were organoleptically acceptable up to 10 and 6 days respectively. Acidity and syneresis increased but pH decreased with storage time in both samples.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81000134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25836
H. Khanal, Sanjita Bhujel
Gastrointestinal parasitic infections are the major sources of diarrheal disease in developing countries and Human Immunodeficiency virus (HIV) infected patients are at the most risk. The objective of this study was to determine the prevalence of intestinal parasitic infections (IPIs) in the HIV-infected individuals visiting different care centers of Morang and Sunsari districts. The present cross-sectional study was conducted from two different HIV rehabilitation centers and one antiretroviral therapy center from eastern Nepal. A semi structured questionnaires was provided to HIV patients and 149 stool specimens were collected to analyze macroscopically and microscopically for the presence of enteric parasites. Data were analyzed by SPSS version 16. A total of 149 HIV seropositive patients with and without diarrhea were included in the study. Overall prevalence rate of enteroparasites was 19.46%. The prevalence rate of enteric parasites in HIV patients showed higher rate of protozoan infections (58.6%) than helminths (41.4%). High prevalence of parasitic infection was seen in male and also among male in the age groups of 31-40 years. The polyparasitism was not detected. A significant difference (p<0.05) was observed in the level of infection of intestinal parasites between the HIV seropositive with gastrointestinal tract (GIT) symptoms and HIV seropositive without GIT symptoms. The enteric parasitic infections were detected in 19.46% among HIV seropositive patients. Early detection of enteric parasitic infections could help in the management and improvement of the quality of life for HIV-infected individuals.
胃肠道寄生虫感染是发展中国家腹泻疾病的主要来源，感染人类免疫缺陷病毒(HIV)的患者面临的风险最大。本研究的目的是确定在Morang和Sunsari地区不同护理中心就诊的艾滋病毒感染者肠道寄生虫感染(IPIs)的患病率。目前的横断面研究是在尼泊尔东部的两个不同的艾滋病毒康复中心和一个抗逆转录病毒治疗中心进行的。对HIV患者进行半结构式问卷调查，并采集149份粪便标本，进行宏观和微观分析肠道寄生虫的存在。数据采用SPSS version 16进行分析。共有149例伴有或不伴有腹泻的HIV血清阳性患者被纳入研究。肠道寄生虫总患病率为19.46%。HIV患者肠道寄生虫患病率中，原生动物感染率(58.6%)高于蠕虫感染率(41.4%)。男性和31-40岁年龄组的男性寄生虫感染率较高。未检测到多寄生现象。有胃肠道症状的HIV血清阳性组与无胃肠道症状的HIV血清阳性组肠道寄生虫感染水平差异有统计学意义(p<0.05)。在HIV血清阳性患者中，肠道寄生虫感染检出率为19.46%。早期发现肠道寄生虫感染有助于管理和改善艾滋病毒感染者的生活质量。
{"title":"Intestinal Parasitosis among Human Immunodeficiency Virus Infected Patients Visiting Different Care Centers of Eastern Nepal","authors":"H. Khanal, Sanjita Bhujel","doi":"10.3126/hijost.v2i0.25836","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25836","url":null,"abstract":"Gastrointestinal parasitic infections are the major sources of diarrheal disease in developing countries and Human Immunodeficiency virus (HIV) infected patients are at the most risk. The objective of this study was to determine the prevalence of intestinal parasitic infections (IPIs) in the HIV-infected individuals visiting different care centers of Morang and Sunsari districts. The present cross-sectional study was conducted from two different HIV rehabilitation centers and one antiretroviral therapy center from eastern Nepal. A semi structured questionnaires was provided to HIV patients and 149 stool specimens were collected to analyze macroscopically and microscopically for the presence of enteric parasites. Data were analyzed by SPSS version 16. A total of 149 HIV seropositive patients with and without diarrhea were included in the study. Overall prevalence rate of enteroparasites was 19.46%. The prevalence rate of enteric parasites in HIV patients showed higher rate of protozoan infections (58.6%) than helminths (41.4%). High prevalence of parasitic infection was seen in male and also among male in the age groups of 31-40 years. The polyparasitism was not detected. A significant difference (p<0.05) was observed in the level of infection of intestinal parasites between the HIV seropositive with gastrointestinal tract (GIT) symptoms and HIV seropositive without GIT symptoms. The enteric parasitic infections were detected in 19.46% among HIV seropositive patients. Early detection of enteric parasitic infections could help in the management and improvement of the quality of life for HIV-infected individuals.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81516656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25834
D. R. Rai, S. Rai
This paper described 44 freshwater algae (except diatoms and red algae) belonging to classes' cyanophyceae, chlorophyceae, charophyceae and euglenophyceae from Hasina wetland and its surrounding area, Sundar- Haraicha, Morang, Nepal. Samples were collected from Budhi Khola, Khayer Khola and ponds and marshy land in Hasina wetland. In total, the largest family was chlorophyceae represented by 30 taxa and the largest genus was Cosmarium represented by 6 taxa. The study showed that this area is rich in algal diversity.
{"title":"Freshwater Algae (Excluding Diatoms and Red Algae) from Hasina Wetland, Sundar Haraicha, Morang, Nepal","authors":"D. R. Rai, S. Rai","doi":"10.3126/hijost.v2i0.25834","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25834","url":null,"abstract":"This paper described 44 freshwater algae (except diatoms and red algae) belonging to classes' cyanophyceae, chlorophyceae, charophyceae and euglenophyceae from Hasina wetland and its surrounding area, Sundar- Haraicha, Morang, Nepal. Samples were collected from Budhi Khola, Khayer Khola and ponds and marshy land in Hasina wetland. In total, the largest family was chlorophyceae represented by 30 taxa and the largest genus was Cosmarium represented by 6 taxa. The study showed that this area is rich in algal diversity.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74929487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Overweight and obesity is an emerging public health issue in developed world and is also rapidly increasing in developing world. This study was carried out to determine the prevalence and associated risk factors of overweight and obesity among women of child bearing age. A cross sectional study was conducted among 206 women residing in Dharan Sub-Metropolitan city of eastern Nepal. BMI, waist circumference and waist to hip ratio were used as indicators for overweight and obesity based on WHO classification and IDF Classification criteria. Association between socioeconomic factors, dietary factors, physical activity, behavioral factors and health related factors with overweight and obesity among women were assessed by using chi square test. Results showed that 50.48% women were overweight and obese (BMI > 25), while 89% based on WHR and, 75.2% based on waist circumference were abdominally obese. The study also showed that age, marital status, size of family, parity, drinking habit and protein intake were major risk factors for overweight and obesity based on BMI. Abdominal obesity based on waist circumference measurement was associated with age, marital status, parity, TV watching while eating habit, contraceptives use, eating outside and protein intake. The high prevalence of overweight and obesity, and diverse natures of associated risk factors among child bearing age women in Dharan showed that more research in this aspect need to be carried out and concerned agencies should focus on identified risk factors for interventions to reduce existing problems of overweight and obesity among women of reproductive age.
{"title":"Risk Factors Associated with Overweight and Obesity among Women of Reproductive Age Residing in Dharan Sub-Metropolitan City, Nepal","authors":"Prabina Bhattarai, Richa Bhattarai, Dambar Bahadur Khadka","doi":"10.3126/hijost.v2i0.25837","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25837","url":null,"abstract":"Overweight and obesity is an emerging public health issue in developed world and is also rapidly increasing in developing world. This study was carried out to determine the prevalence and associated risk factors of overweight and obesity among women of child bearing age. A cross sectional study was conducted among 206 women residing in Dharan Sub-Metropolitan city of eastern Nepal. BMI, waist circumference and waist to hip ratio were used as indicators for overweight and obesity based on WHO classification and IDF Classification criteria. Association between socioeconomic factors, dietary factors, physical activity, behavioral factors and health related factors with overweight and obesity among women were assessed by using chi square test. Results showed that 50.48% women were overweight and obese (BMI > 25), while 89% based on WHR and, 75.2% based on waist circumference were abdominally obese. The study also showed that age, marital status, size of family, parity, drinking habit and protein intake were major risk factors for overweight and obesity based on BMI. Abdominal obesity based on waist circumference measurement was associated with age, marital status, parity, TV watching while eating habit, contraceptives use, eating outside and protein intake. The high prevalence of overweight and obesity, and diverse natures of associated risk factors among child bearing age women in Dharan showed that more research in this aspect need to be carried out and concerned agencies should focus on identified risk factors for interventions to reduce existing problems of overweight and obesity among women of reproductive age.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73731893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25851
I. Koirala
We have investigated the effect of surface coordination of atoms on the surface properties of Cd-Ga and Cd-Zn liquid alloys by varying their surface coordination fractions using statistical mechanics model. Surface tension and surface concentration did not have significant effect on the calculation of both surface tension and surface concentration of two alloys. The computation of the concentration fluctuations at the surface revealed that it was sensitive to the surface coordination fractions of both segregating systems. In those alloys we found that the computation of the Warren-Cowley short rang order parameter was influenced by the surface coordination fractions.
{"title":"Effects of surface coordination of atoms on the surface properties of Cd-X (X= Ga, Zn) liquid alloys","authors":"I. Koirala","doi":"10.3126/hijost.v2i0.25851","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25851","url":null,"abstract":"We have investigated the effect of surface coordination of atoms on the surface properties of Cd-Ga and Cd-Zn liquid alloys by varying their surface coordination fractions using statistical mechanics model. Surface tension and surface concentration did not have significant effect on the calculation of both surface tension and surface concentration of two alloys. The computation of the concentration fluctuations at the surface revealed that it was sensitive to the surface coordination fractions of both segregating systems. In those alloys we found that the computation of the Warren-Cowley short rang order parameter was influenced by the surface coordination fractions.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"61 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90136106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25844
Arjun Ghimire, N. Magar
Curry leaves (Murraya koenigii L.) are the sweet smelling leaves of small tree of Rutaceae family native to Southwest Asia. In this study, the effect of temperatures (50, 55 and 60°C) on the drying of curry leaves was investigated. The experimental data were fitted to six thin layer mathematical models (Newton, Page, Handerson and Pabis, logarithmic, two-term exponential and Midilli et al). The models were evaluated in terms of coefficient of determination (R2), chi square (χ2) and root mean square error (RMSE). The Midilli et al model was best fitted to the experimental data of all the models evaluated. The effective diffusivity was calculated using Fick's diffusion equation, and the value varied from 2.07×10-12 m2/s to 2.643×10-12 m2/s. The activation energy and the diffusivity constant were found to be 21.808 kJ/mol and 4.667×10-8 m2/s respectively.
{"title":"Thin Layer Drying Kinetics Modelling of Curry Leaves (Murraya koenigii L.) in Cabinet Dryer","authors":"Arjun Ghimire, N. Magar","doi":"10.3126/hijost.v2i0.25844","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25844","url":null,"abstract":"Curry leaves (Murraya koenigii L.) are the sweet smelling leaves of small tree of Rutaceae family native to Southwest Asia. In this study, the effect of temperatures (50, 55 and 60°C) on the drying of curry leaves was investigated. The experimental data were fitted to six thin layer mathematical models (Newton, Page, Handerson and Pabis, logarithmic, two-term exponential and Midilli et al). The models were evaluated in terms of coefficient of determination (R2), chi square (χ2) and root mean square error (RMSE). The Midilli et al model was best fitted to the experimental data of all the models evaluated. The effective diffusivity was calculated using Fick's diffusion equation, and the value varied from 2.07×10-12 m2/s to 2.643×10-12 m2/s. The activation energy and the diffusivity constant were found to be 21.808 kJ/mol and 4.667×10-8 m2/s respectively.","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73707301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-01DOI: 10.3126/hijost.v2i0.25841
S. Yadav, P. R. Dahal, Shivjee Sah, V. Sharma
Urinary tract infection (UTI) is one of the most common diseases encountered worldwide and is a major public health problem in terms of morbidity and financial costs. A cross-sectional study was conducted in Alka Hospital, Lalitpur, Nepal from February to July, 2014. A total of 353 midstream urine samples were collected from postmenopausal women visiting Alka Hospital, Lalitpur, Nepal. The samples were examined by microscopically and culture methods. The isolated organisms were identified by conventional microbiological methods. Antibiotic susceptibility test was performed by modified Kirby-Bauer disc diffusion method according to CLSI (2011) guidelines. Among 353 urine samples processed, 32 % (113) showed significant bacteriuria. Out of 113 bacterial isolates, the prevalence of gram negative bacteria was 97.3% (110) while that of gram positive was 2.7% (3). The most predominating organisms causing UTI were Escherichia coli (84.9%) followed by Klebsiella pneumoniae (5.3%), Enterococcus faecalis (1.7%), Providencia spp. (1.7%), Klebsiella oxytoca (1.7%), Proteus mirabilis (1.7%), Proteus vulgaris (0.9%), Citrobacter freundii (0.9%) and Staphylococcus aureus (0.9%). Antibiotic susceptibility tests of the isolates showed that, most of the gram negative bacterial isolates were sensitive to Piperacillin+Tazobactam followed by Amikacin, Imipenem and Nitrofurantoin, while they were resistant to Amoxicillin. All gram positive isolates were sensitive to Amoxicillin and resistant to Gentamycin. This study showed that higher aged postmenopausal women (>80 years) were at higher risk for UTI than those of lower aged ones (<80 years).
{"title":"Bacteriological Profile of Urinary Tract Infections among Postmenopausal Women Visiting Alka Hospital, Lalitpur, Nepal","authors":"S. Yadav, P. R. Dahal, Shivjee Sah, V. Sharma","doi":"10.3126/hijost.v2i0.25841","DOIUrl":"https://doi.org/10.3126/hijost.v2i0.25841","url":null,"abstract":"Urinary tract infection (UTI) is one of the most common diseases encountered worldwide and is a major public health problem in terms of morbidity and financial costs. A cross-sectional study was conducted in Alka Hospital, Lalitpur, Nepal from February to July, 2014. A total of 353 midstream urine samples were collected from postmenopausal women visiting Alka Hospital, Lalitpur, Nepal. The samples were examined by microscopically and culture methods. The isolated organisms were identified by conventional microbiological methods. Antibiotic susceptibility test was performed by modified Kirby-Bauer disc diffusion method according to CLSI (2011) guidelines. Among 353 urine samples processed, 32 % (113) showed significant bacteriuria. Out of 113 bacterial isolates, the prevalence of gram negative bacteria was 97.3% (110) while that of gram positive was 2.7% (3). The most predominating organisms causing UTI were Escherichia coli (84.9%) followed by Klebsiella pneumoniae (5.3%), Enterococcus faecalis (1.7%), Providencia spp. (1.7%), Klebsiella oxytoca (1.7%), Proteus mirabilis (1.7%), Proteus vulgaris (0.9%), Citrobacter freundii (0.9%) and Staphylococcus aureus (0.9%). Antibiotic susceptibility tests of the isolates showed that, most of the gram negative bacterial isolates were sensitive to Piperacillin+Tazobactam followed by Amikacin, Imipenem and Nitrofurantoin, while they were resistant to Amoxicillin. All gram positive isolates were sensitive to Amoxicillin and resistant to Gentamycin. This study showed that higher aged postmenopausal women (>80 years) were at higher risk for UTI than those of lower aged ones (<80 years).","PeriodicalId":12935,"journal":{"name":"Himalayan Journal of Science and Technology","volume":"127 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75843230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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