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Evaluation of a pharmacy based personal health record by elderly respiratory patients 基于药房的老年呼吸道患者个人健康记录评价
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa748
E. Metting, A. Baron, N. Chavannes, A. Tran, Sanne van Luenen, C. Jong
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引用次数: 0
mHealth mood monitoring for people with COPD 慢性阻塞性肺病患者的移动健康情绪监测
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa2236
Maxine E. Whelan, Carmelo Velardo, H. Rutter, L. Tarassenko, A. Farmer
Background: Co-morbid anxiety and depression can add to the complexity of chronic obstructive pulmonary disease (COPD). While digital health technologies for people with COPD support monitoring of vital signs (including oxygen saturation and pulse), mood is not routinely monitored even though it could support self-management. Aim: To report adherence to mood self-monitoring and levels of anxiety and depression for people with COPD. Methods: The sElf-management anD support proGrammE (EDGE) was a 12-month randomised controlled trial involving people with COPD. Participants were asked to complete an anxiety (General Anxiety Disorder, GAD) and depression questionnaire (Patient Health Questionnaire, PHQ) every 4 weeks via a tablet computer. Health status (EuroQol 5 Dimensions, EQ5D), respiratory impairment (St George’s Respiratory Questionnaire-COPD, SGRQ-C) and smoking status were recorded. Answering ≥10 of 12 months was adherent and PHQ and GAD scores of ≥5 positive. Results: Of 106 (99%) participants entering mood data, 81 participants were adherent. There were more ex-smokers in the adherent participant pool (n=71 of 81) compared with the non-adherent participants (n=13 of 25); p Conclusions: People with COPD can self-monitor mood over 12 months. With >50% of participants suggesting an elevated risk of both anxiety and depression (associated with a lower health status and higher respiratory impairment), the opportunity to regularly monitor mood in this patient population could offer useful information for comorbidity management.
背景:共病焦虑和抑郁可增加慢性阻塞性肺疾病(COPD)的复杂性。虽然数字健康技术支持对COPD患者的生命体征(包括氧饱和度和脉搏)进行监测,但情绪并没有得到常规监测,尽管它可以支持自我管理。目的:报告COPD患者的情绪自我监测依从性以及焦虑和抑郁水平。方法:自我管理和支持计划(EDGE)是一项为期12个月的随机对照试验,涉及COPD患者。参与者被要求每4周通过平板电脑完成一份焦虑(一般焦虑障碍,GAD)和抑郁问卷(患者健康问卷,PHQ)。记录健康状况(EuroQol 5 Dimensions, EQ5D)、呼吸障碍(圣乔治呼吸问卷- copd, SGRQ-C)和吸烟状况。在12个月中回答≥10为坚持,PHQ和GAD评分≥5为阳性。结果:106名(99%)参与者输入情绪数据,81名参与者坚持。坚持戒烟的参与者(81人中有71人)比不坚持戒烟的参与者(25人中有13人)要多;结论:COPD患者可以在12个月内自我监测情绪。有超过50%的参与者表示焦虑和抑郁的风险升高(与较低的健康状况和较高的呼吸障碍有关),有机会定期监测该患者人群的情绪可以为合并症管理提供有用的信息。
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引用次数: 0
eHealth self-management support after high-altitude climate treatment (HACT) of severe asthma: a randomised controlled trial 重度哮喘高海拔气候治疗(HACT)后电子健康自我管理支持:一项随机对照试验
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa2230
L. Rijssenbeek-Nouwens, Thijs Beerthuizen, J. Snoeck-Stroband, J. Sont
Background: In severe asthma, it has been shown that HACT improves asthma control. However, asthma may worsen after finishing HACT and returning to sea level. We assessed the effectiveness of patient tailored eHealth self-management support in addition to standard care after discharge from HACT. Methods: In a RCT with 1-year follow-up 62 asthmatic adults were randomised to receive either eHealth self-management support (PatientCoach) in addition to standard care (N=33), or standard care only (N=29) after discharge from a 12-week multi-disciplinary rehabilitation program at a high-altitude asthma centre. Endpoints were changes in asthma-related quality of life (QoL: AQLQ, the higher the better) and asthma control (ACQ, the lower the better), both with a minimally important difference of 0.5 points. Results: Asthma-related QoL and asthma control gradually declined over time in the standard care group, whereas there was less decline in the eHealth group. In both endpoints, mixed-model analysis showed a positive effect in favour of eHealth during follow-up (AQLQ difference 0.39 (0.092 to 0.69); P = .01; ACQ difference -0.50 (-0.86 to -0.15); P = .006), which was especially found in patients with uncontrolled asthma at discharge (AQLQ difference 0.59 (0.19 to 0.99); P = .003; ACQ difference -0.73 (-1.18 to -0.28), P = .002). Conclusion: eHealth self-management support was associated with a smaller gradual decline in QoL and asthma control, especially in patients with suboptimal asthma control after discharge from HACT. eHealth support of adults with severe asthma after discharge from HACT seems feasible and effective to maintain quality of life and asthma control.
背景:在严重哮喘中,HACT已被证明可以改善哮喘控制。然而,在完成HACT并返回海平面后,哮喘可能会恶化。我们评估了患者定制的电子健康自我管理支持以及HACT出院后的标准护理的有效性。方法:在一项为期1年随访的随机对照试验中,62名哮喘成人在高原哮喘中心进行了为期12周的多学科康复计划后,随机分为两组,一组接受eHealth自我管理支持(PatientCoach)和标准治疗(N=33),另一组仅接受标准治疗(N=29)。终点是哮喘相关生活质量(QoL: AQLQ,越高越好)和哮喘控制(ACQ,越低越好)的变化,两者均有0.5点的最小重要差异。结果:标准治疗组哮喘相关生活质量和哮喘控制随时间逐渐下降,而电子健康组下降较少。在两个终点,混合模型分析显示,随访期间eHealth的积极影响(AQLQ差异0.39(0.092至0.69);P = 0.01;ACQ差-0.50 (-0.86 ~ -0.15);P = 0.006),特别是在出院时哮喘未控制的患者中(AQLQ差值0.59 (0.19 ~ 0.99);P = .003;ACQ差-0.73 (-1.18 ~ -0.28),P = 0.002)。结论:eHealth自我管理支持与生活质量和哮喘控制的逐渐下降有关,特别是在HACT出院后哮喘控制不佳的患者中。成人重症哮喘患者从HACT出院后的电子健康支持似乎是可行和有效的,以维持生活质量和哮喘控制。
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引用次数: 1
Are mobile device applications effective at supporting COPD self-management compared to usual care? 与常规护理相比,移动设备应用在支持COPD自我管理方面是否有效?
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa747
George Shaw, Maxine E. Whelan, L. Armitage, A. Farmer
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引用次数: 0
Respiratory system auscultation using machine learning - a big step towards objectivisation? 使用机器学习的呼吸系统听诊——向客观化迈出了一大步?
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa2231
Tomasz Grzywalski, Marcin Szajek, Honorata Hafke-Dys, A. Bręborowicz, J. Kocinski, Anna Pastusiak, Riccardo Belluzzo
A stethoscope, introduced more than two centuries ago, is still a tool providing potentially valuable information gained during one of the most common examinations. However, the biggest drawback of auscultation is its subjectivity. It depends mainly on the experience and ability of the doctor to perceive and distinguish pathological signals. Many research has shown very low efficiency of doctors in this area. Moreover, most of physicians are aware of this problem and needs supporting device. Therefore we have developed the Artificial Intelligence (AI) algorithms which recognise pathological sounds (wheezes, rhonchi, fine and coarse crackles). Here we present the comparison of the performance of physicians and AI in detection of those sounds. A database of more than 10 000 recordings described by a consilium of specialists (pulmonologists and acousticians) was used for AI learning. Then another set of more than 500 real auscultatory sounds were used to investigate the efficiency of AI in comparison to a group of doctors. The standard F1-score was used for evaluation, because it considers both the precision and the recall. For each phenomena, the results for the AI is higher than for doctors with an average advantage of 8.4 percentage points, reaching even 13,5 p.p. for fine crackles. The results suggest that the implementation of AI can significantly improve the efficiency of auscultation in everyday practice making it more objective, leading to a minimization of errors. The solution is now being tested with a group of hospitals and medical providers and proves its efficiency and usability in everyday practice making this examination faster and more reliable.
听诊器是在两个多世纪前引入的,它仍然是一种工具,可以在最常见的检查中获得潜在的有价值的信息。但听诊最大的缺点是主观性强。它主要依靠医生的经验和能力来感知和区分病理信号。许多研究表明,医生在这方面的效率非常低。此外,大多数医生都意识到这个问题,并需要支持设备。因此,我们开发了人工智能(AI)算法来识别病理声音(喘息声、隆隆声、细声和粗声)。在这里,我们比较了医生和人工智能在检测这些声音方面的表现。人工智能学习使用了一个由专家(肺科医生和声学家)组成的超过1万份录音的数据库。然后,另一组超过500个真实的听诊声音被用来研究人工智能与一组医生的效率。采用标准的f1分进行评价,因为它同时考虑了准确率和召回率。对于每种现象,人工智能的结果都高于医生,平均优势为8.4个百分点,对于细微裂纹甚至达到13.5个百分点。结果表明,人工智能的实施可以显著提高听诊在日常练习中的效率,使听诊更加客观,从而最大限度地减少错误。目前,该解决方案正在多家医院和医疗机构进行测试,并在日常实践中证明了其效率和可用性,使这项检查更快、更可靠。
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引用次数: 2
Validation of app and telephonic versions of the Control of Allergic Rhinitis and Asthma Test (CARAT) 变应性鼻炎和哮喘控制测试(CARAT)应用和电话版本的验证
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa741
C. I. Oliveira Jácome, R. Almeida, A. Pereira, P. Vieira-Marques, M. Couto, A. Todo Bom, J. Azevedo, P. Leiria Pinto, A. Castro Neves, N. Pinto, F. Todo Bom, Alberto Costa, J. Cardoso, M. Emiliano, R. Gerardo, A. Arrobas, M. Valério, C. Chaves Loureiro, L. Maia Santos, C. Lozoya, A. Mendes, F. Menezes, R. Gomes, J. C. Cidrais Rodrigues, Georgeta Oiveira, N. Santos, R. Câmara, D. Bordalo, J. Ferreira, R. Rodrigues Alves, Rui Silva, C. Alves, A. Carvalho, F. Teixeira, Diana Silva, M. Cálix, C. Lopes, L. Taborda-Barata, J. Almeida Fonseca
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引用次数: 1
Digitalising the personalised asthma action plan (PAAP) - a multi-perspective qualitative study 数字化个性化哮喘行动计划(PAAP) -一项多视角定性研究
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa736
U. Vaghela, James Moss, M. Partridge, A. Simoni, A. Bush
Asthma control can be optimised by medication compliance, trigger avoidance and recognising when and how to react to worsening control and asthma attacks. Failure to support this, by the under-issuing of personalised asthma action plans (PAAPs) by healthcare professionals (HCPs) and under-utilisation by patients, contributes substantially to asthma deaths (NRAD. RCP 2014;27). Since there is evidence that mobile applications can improve chronic disease health outcomes, we hypothesised PAAP digitalisation can improve current asthma self-management approaches. To assess whether and how a digital PAAP could address barriers to PAAP implementation, we performed focus group discussions with primary (n=3) and secondary (n=5) care doctors and nurses involved in asthma care, and patients (n=5) of variable age (18-65) and disease severity (moderate to poor asthma control over 1 year). Within group coding and categorisation contributed to a cross-case thematic framework for analysis. We found that patients and HCPs experience decision-making uncertainty using current PAAPs. In primary care, there is no uniformity in PAAP usage and methods to evaluate self-management efficacy. A digital PAAP would enable longitudinal data recording with objective monitoring capabilities. Patients valued the interactive, real-time support it could provide in affirming treatment escalation and medication choices. Nevertheless, a digital tool may have adverse effects, with concerns over data overload, quality and overdependence on technology. However, if built using a validated algorithm and in collaboration with key stakeholders, digital PAAPs could optimise self-management assessment and execution for patients and HCPs.
哮喘控制可以通过药物依从性、避免触发和识别何时以及如何应对控制恶化和哮喘发作来优化。由于医疗保健专业人员(HCPs)发布的个性化哮喘行动计划(paap)不足以及患者的利用不足,未能支持这一点,这在很大程度上导致了哮喘死亡(NRAD)。RCP 2014; 27)。由于有证据表明移动应用程序可以改善慢性疾病的健康结果,我们假设PAAP数字化可以改善当前的哮喘自我管理方法。为了评估数字PAAP是否以及如何解决PAAP实施的障碍,我们与参与哮喘护理的初级(n=3)和二级(n=5)护理医生和护士以及不同年龄(18-65岁)和疾病严重程度(1年内哮喘控制中度至不良)的患者(n=5)进行了焦点小组讨论。在组内编码和分类有助于跨案例专题框架的分析。我们发现患者和HCPs在使用当前PAAPs时存在决策不确定性。在初级保健中,PAAP的使用和评估自我管理疗效的方法没有统一。数字PAAP将使纵向数据记录具有客观监测能力。患者重视它在确定治疗升级和药物选择方面提供的交互式实时支持。然而,数字工具可能会带来负面影响,比如数据过载、质量问题和对技术的过度依赖。然而,如果使用经过验证的算法并与关键利益相关者合作,数字paap可以优化患者和HCPs的自我管理评估和执行。
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引用次数: 0
Tele-rehabilitation program in Idiopathic Pulmonary Fibrosis 特发性肺纤维化的远程康复方案
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa2232
José Cerdán de las Heras, O. Hilberg, A. Løkke, E. Bendstrup
Background: In Idiopathic Pulmonary Fibrosis (IPF), pulmonary rehabilitation (PR) is recommended to improve quality of life (QoL) and exercise capacity (EC). Not all patients with IPF can participate in hospital based PR due to frailty and long travelling distances. Tele-rehabilitation (TR) might be an alternative solution. We investigated the feasibility and efficacy of TR on EC and QoL in patients with IPF. Method: Single-center, prospective, randomized study, including stable patients with IPF for 3 months (3M) of TR: video and chat-consultations with a real physiotherapist and workout sessions with a virtual autonomous physiotherapist agent (VAPA). Forced vital capacity (FVC), diffusion capacity (DLCO) was registered at baseline (BL). EC evaluated with 6-minute-walk-test distance (6MWTD) and QoL with Kings Brief Interstitial Lung Diseases (KBILD) and St. George’s Respiratory Questionnaire (SGRQ) before and after 3M of training. Control patients did not receive hospital-based PR. Results: 29 patients were included, 15 in the intervention group (IN) (male 86.7%, mean age 69.7±8.7 years, FVC % 76.7±16.4, DLCO % 46.5±11), and 14 in the control group (CO) (male 57.1%, mean age 72±7.6 years, FVC % 90.8±16.5, DLCO % 55±14 ). BL and 3M data can be seen in table. Conclusion: TR with VAPA is feasible for IPF. Improved EC was shown after 3M follow up.
背景:在特发性肺纤维化(IPF)中,肺康复(PR)被推荐用于改善生活质量(QoL)和运动能力(EC)。并非所有IPF患者都能参加基于医院的PR,因为他们身体虚弱且旅行距离较远。远程康复(TR)可能是另一种解决方案。我们探讨了TR对IPF患者EC和QoL的可行性和有效性。方法:单中心、前瞻性、随机研究,纳入稳定的IPF患者进行3个月(3M)的TR:与真实物理治疗师进行视频和聊天咨询,并使用虚拟自主物理治疗师代理(VAPA)进行锻炼。用力肺活量(FVC)和弥散量(DLCO)分别记录于基线(BL)。采用6分钟步行测试距离(6MWTD)、king短暂间质性肺疾病(KBILD)和St. George呼吸问卷(SGRQ)评估训练前后的EC。结果:纳入29例患者,干预组(in) 15例(男性86.7%,平均年龄69.7±8.7岁,FVC % 76.7±16.4,DLCO % 46.5±11),对照组(CO) 14例(男性57.1%,平均年龄72±7.6岁,FVC % 90.8±16.5,DLCO % 55±14)。BL和3M数据见表。结论:应用VAPA治疗IPF是可行的。3M随访后,EC有所改善。
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引用次数: 2
Is poor asthma self-management due to failure to recognise symptoms or failure to act? Novel insights from mining large-scale clinical observational study 哮喘自我管理不良是由于未能认识到症状还是未能采取行动?挖掘大规模临床观察研究的新见解
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa746
S. A. Shah
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引用次数: 0
Improving inhaler technique in asthma/COPD by mHealth: a Belgian RCT mHealth改善哮喘/COPD吸入器技术:比利时的一项随机对照试验
Pub Date : 2019-09-28 DOI: 10.1183/13993003.congress-2019.pa2235
L. Lahousse, Anna Vanoverschelde
Introduction: Despite inhalation medication being the main treatment of asthma/COPD patients, only one third of patients demonstrates a correct inhaler technique. While pharmaceutical care has shown to effectively improve inhaler technique, the integration of the MyPuff app to support continued patient education at home has not been evaluated. Aim: To investigate improvement in inhaler technique by integrating a mHealth app compared to standard information leaflets into pharmaceutical care provided to patients with asthma/COPD. Methods: This 3 month Belgian community pharmacy-based open RCT enrolled adult patients, from March till December 2018, with registered inhaler therapy for asthma/COPD. Randomization was stratified according to the 9 community pharmacies to either receive aid for using the MyPuff-app, or a standard information leaflet to further optimize their inhaler technique at home. Inhaler technique was scored by comparing the patient demonstration with the correct protocol per device. Results: Seventy community patients (median age 64y, 56% females; 44% asthma, 39% COPD, 17% ACO) were randomized to the app (n=37; 53%) or leaflet (n=33; 47%). In 60 patients with follow-up, mean score on inhaler technique improved from 49% (SD 28%) to 65% (SD 33%) and the number of patients making critical errors dropped from 52% to 33%. Patients in the app group did not improve more than in the leaflet group. The reported use of the app (13%) was lower than the leaflet use (57%). Conclusion: The inhaler technique of asthma/COPD patients was improved 3 months after pharmaceutical care delivery, however, providing an app to further optimize inhaler technique at home was not better than providing an information leaflet.
尽管吸入性药物治疗是哮喘/慢性阻塞性肺病患者的主要治疗方法,但只有三分之一的患者掌握了正确的吸入器技术。虽然药物治疗已经证明可以有效地改善吸入器技术,但整合MyPuff应用程序来支持患者在家中继续接受教育还没有得到评估。目的:通过将移动健康应用程序与标准信息传单相比较,研究为哮喘/慢性阻塞性肺病患者提供的药学服务中吸入器技术的改进。方法:这项为期3个月的比利时社区药房开放随机对照试验,于2018年3月至12月招募成年患者,注册吸入器治疗哮喘/COPD。根据9家社区药房进行随机分层,要么接受使用MyPuff-app的援助,要么接受标准信息传单,以进一步优化他们在家使用吸入器的技术。通过比较患者演示和每个设备的正确方案,对吸入器技术进行评分。结果:70例社区患者(中位年龄64岁,女性56%;44%哮喘,39% COPD, 17% ACO)随机分配到app (n=37;53%)或小叶(n=33;47%)。在随访的60例患者中,吸入器技术的平均评分从49% (SD 28%)提高到65% (SD 33%),发生严重错误的患者数量从52%下降到33%。应用程序组患者的改善并不比单张组多。该应用程序的使用率(13%)低于传单的使用率(57%)。结论:哮喘/慢性阻塞性肺病患者吸入器技术在药学服务提供3个月后得到改善,但在家中提供应用程序进一步优化吸入器技术并不比提供信息单张更好。
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引用次数: 1
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M-health/e-health
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