Pub Date : 2025-12-11DOI: 10.1007/s10029-025-03522-5
Devin J Clegg, Jacob H Creighton, Hunter L White, R Eric Heidel, Jonathan A Laredo, Josephine A Fuller, Sarah M Budney, Kyle L Kleppe, Kaela E Blake, Aldo Fafaj
Purpose: Parastomal hernias are a common complication after ostomy creation with high morbidity. Minimally invasive Sugarbaker mesh-based repairs have shown improved outcomes. Laparoscopic (LPHR) and robotic-assisted (RPHR) Sugarbaker parastomal hernia repairs were compared.
Methods: Retrospective analysis of the Abdominal Core Health Quality Collaborative (ACHQC) database was conducted for elective, minimally invasive Sugarbaker parastomal hernia repair with permanent synthetic mesh from January 2014 to December 2023. Patients were grouped by surgical approach: RPHR or LPHR. Primary outcome was pragmatic hernia recurrence. Secondary outcomes included average pain intensity, hernia-related quality of life, and 30/90-day complications. Statistical analyses included chi-square, t-tests, and Mann-Whitney U tests.
Results: Three hundred sixty-eight patients were included (RPHR: n = 260; LPHR: n = 108). Demographics and comorbidities were similar. RPHR involved more mesh excisions (37.5% vs. 4.3%; P = .009), hernia with longer lengths (8.3 cm vs. 6.4 cm; P < .001), and more frequent fascial closure (94.4% vs. 48.1%; P < .001). Recurrence within one year was lower after RPHR (20.9% vs. 40.5%; P = .03), but no significant differences were observed between postoperative years one through six. No differences in pain or quality-of-life outcomes were noted between groups, but both groups demonstrated significant improvements in hernia-related quality-of-life over one year.
Conclusion: Recurrence within one year was lower after RPHR compared to LPHR. Longer-term recurrence rates were similar between approaches. However, long-term recurrence findings are limited by low follow-up rates. Both approaches significantly improved hernia-related quality-of-life. Over time, recurrence may be more dependent on the altered anatomy and physiology of the stoma-affected abdominal wall rather than the specific minimally invasive approach used.
目的:造口旁疝是造口术后常见的并发症,发病率高。基于Sugarbaker网的微创修复显示出改善的效果。比较腹腔镜(LPHR)和机器人辅助(RPHR) Sugarbaker造口旁疝修补术。方法:回顾性分析2014年1月至2023年12月选择性微创Sugarbaker造口旁疝永久性合成补片修补术的腹部核心健康质量协作(ACHQC)数据库。患者按手术入路分组:RPHR或LPHR。主要结果为实用疝复发。次要结局包括平均疼痛强度、疝气相关生活质量和30/90天并发症。统计分析包括卡方检验、t检验和Mann-Whitney U检验。结果:纳入368例患者(RPHR: n = 260; LPHR: n = 108)。人口统计学和合并症相似。RPHR涉及更多的补片切除(37.5% vs. 4.3%);结论:与LPHR相比,RPHR术后1年内的复发率较低。两种方法的长期复发率相似。然而,长期复发发现受到低随访率的限制。两种方法都显著改善了疝气相关的生活质量。随着时间的推移,复发可能更多地取决于受造口影响的腹壁的解剖和生理改变,而不是采用特定的微创入路。
{"title":"Comparison of recurrence and quality-of-Life outcomes after robotic versus laparoscopic parastomal hernia repair: a retrospective analysis of the abdominal core health quality collaborative.","authors":"Devin J Clegg, Jacob H Creighton, Hunter L White, R Eric Heidel, Jonathan A Laredo, Josephine A Fuller, Sarah M Budney, Kyle L Kleppe, Kaela E Blake, Aldo Fafaj","doi":"10.1007/s10029-025-03522-5","DOIUrl":"https://doi.org/10.1007/s10029-025-03522-5","url":null,"abstract":"<p><strong>Purpose: </strong>Parastomal hernias are a common complication after ostomy creation with high morbidity. Minimally invasive Sugarbaker mesh-based repairs have shown improved outcomes. Laparoscopic (LPHR) and robotic-assisted (RPHR) Sugarbaker parastomal hernia repairs were compared.</p><p><strong>Methods: </strong>Retrospective analysis of the Abdominal Core Health Quality Collaborative (ACHQC) database was conducted for elective, minimally invasive Sugarbaker parastomal hernia repair with permanent synthetic mesh from January 2014 to December 2023. Patients were grouped by surgical approach: RPHR or LPHR. Primary outcome was pragmatic hernia recurrence. Secondary outcomes included average pain intensity, hernia-related quality of life, and 30/90-day complications. Statistical analyses included chi-square, t-tests, and Mann-Whitney U tests.</p><p><strong>Results: </strong>Three hundred sixty-eight patients were included (RPHR: n = 260; LPHR: n = 108). Demographics and comorbidities were similar. RPHR involved more mesh excisions (37.5% vs. 4.3%; P = .009), hernia with longer lengths (8.3 cm vs. 6.4 cm; P < .001), and more frequent fascial closure (94.4% vs. 48.1%; P < .001). Recurrence within one year was lower after RPHR (20.9% vs. 40.5%; P = .03), but no significant differences were observed between postoperative years one through six. No differences in pain or quality-of-life outcomes were noted between groups, but both groups demonstrated significant improvements in hernia-related quality-of-life over one year.</p><p><strong>Conclusion: </strong>Recurrence within one year was lower after RPHR compared to LPHR. Longer-term recurrence rates were similar between approaches. However, long-term recurrence findings are limited by low follow-up rates. Both approaches significantly improved hernia-related quality-of-life. Over time, recurrence may be more dependent on the altered anatomy and physiology of the stoma-affected abdominal wall rather than the specific minimally invasive approach used.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"27"},"PeriodicalIF":2.4,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145722687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-02DOI: 10.1007/s10029-025-03511-8
Laurits Leander, Erling Oma, Regnar Bøge Arnesen, Lars Nannestad Jorgensen
Abcstrat: PURPOSE: Parastomal hernia is a common complication that may require emergency repair (ePHR). Although 20% of PHRs are performed in an emergency setting, treatment strategies and outcomes are poorly documented. This systematic review aimed to determine the optimal strategy and surgical technique for ePHR.
Methods: A literature search was conducted in PubMed, Embase, Web of Science, CINAHL, Cochrane Library and Google Scholar for original studies reporting on ePHR. Primary outcome was rate of reoperation within 90 days. Secondary outcomes were length of stay (LOS) as well as 90-day rates of surgical site infection (SSI), other complications, and mortality.
Results: The search identified 328 studies of which 10 was included totalling 21,877 patients undergoing ePHR. Mean rates for short-term reoperation, SSI, other complications and mortality were 39% (95%-confidence interval 31-49%), 24% (15-37%), 44% (30-59%) and 12% (8-16%), respectively. Median LOS varied between 7 and 13 days. Insufficient data precluded meta-analysis for comparison of (1) open and laparoscopic repair, (2) local repair, relocation and reversal, as well as (3) mesh and suture repair.
Conclusion: Besides considerable LOS, ePHR was associated with high morbidity and mortality. The limited available literature and conflicting data did not entitle recommendation of a specific surgical approach for this patient group. There was no evidence that suggested mesh should be avoided in ePHR. Future studies should investigate a two-stage approach with initial damage control versus one-stage definitive repair. Moreover, studies are warranted to compare open and minimally invasive surgery for ePHR.
摘要:目的:造口旁疝是一种常见的并发症,可能需要紧急修复(ePHR)。虽然20%的phrr是在紧急情况下进行的,但治疗策略和结果的记录很差。本系统综述旨在确定epr的最佳策略和手术技术。方法:在PubMed、Embase、Web of Science、CINAHL、Cochrane Library和谷歌Scholar等网站检索关于ePHR的原创研究。主要观察指标为90天内的再手术率。次要结局是住院时间(LOS)、90天手术部位感染率(SSI)、其他并发症和死亡率。结果:检索确定了328项研究,其中10项纳入了21,877例接受ePHR的患者。短期再手术、SSI、其他并发症和死亡率的平均发生率分别为39%(95%可信区间31-49%)、24%(15-37%)、44%(30-59%)和12%(8-16%)。平均生存期在7到13天之间。由于数据不足,无法对(1)开放式和腹腔镜修复,(2)局部修复、再定位和翻转,以及(3)补片和缝合修复进行meta分析。结论:除了严重的LOS外,ePHR的发病率和死亡率也很高。有限的可用文献和相互矛盾的数据并没有为该患者组推荐特定的手术方法。没有证据表明在心电图中应避免补片。未来的研究应该探讨两阶段的方法,即初始损伤控制与一阶段的最终修复。此外,研究需要比较开放手术和微创手术对epr的影响。
{"title":"Emergency parastomal hernia repair - a systematic review.","authors":"Laurits Leander, Erling Oma, Regnar Bøge Arnesen, Lars Nannestad Jorgensen","doi":"10.1007/s10029-025-03511-8","DOIUrl":"10.1007/s10029-025-03511-8","url":null,"abstract":"<p><strong>Abcstrat: </strong>PURPOSE: Parastomal hernia is a common complication that may require emergency repair (ePHR). Although 20% of PHRs are performed in an emergency setting, treatment strategies and outcomes are poorly documented. This systematic review aimed to determine the optimal strategy and surgical technique for ePHR.</p><p><strong>Methods: </strong>A literature search was conducted in PubMed, Embase, Web of Science, CINAHL, Cochrane Library and Google Scholar for original studies reporting on ePHR. Primary outcome was rate of reoperation within 90 days. Secondary outcomes were length of stay (LOS) as well as 90-day rates of surgical site infection (SSI), other complications, and mortality.</p><p><strong>Results: </strong>The search identified 328 studies of which 10 was included totalling 21,877 patients undergoing ePHR. Mean rates for short-term reoperation, SSI, other complications and mortality were 39% (95%-confidence interval 31-49%), 24% (15-37%), 44% (30-59%) and 12% (8-16%), respectively. Median LOS varied between 7 and 13 days. Insufficient data precluded meta-analysis for comparison of (1) open and laparoscopic repair, (2) local repair, relocation and reversal, as well as (3) mesh and suture repair.</p><p><strong>Conclusion: </strong>Besides considerable LOS, ePHR was associated with high morbidity and mortality. The limited available literature and conflicting data did not entitle recommendation of a specific surgical approach for this patient group. There was no evidence that suggested mesh should be avoided in ePHR. Future studies should investigate a two-stage approach with initial damage control versus one-stage definitive repair. Moreover, studies are warranted to compare open and minimally invasive surgery for ePHR.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"26"},"PeriodicalIF":2.4,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145654363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Inguinal hernia is a common occurrence affecting one in four men. Recurrence is a major clinical pitfall that affects about 10% of patients with increased recurrence and postoperative complications after a revision repair. Reoperation due to metachronous contralateral inguinal hernia is another possible outcome. The impact of minimally invasive surgery (MIS) techniques on inguinal hernia recurrence rates as compared to open surgery is less clear and further confounded by the adoption of robotic approaches. The aim of this study was to compare reoperation rates.
Methods: Adult patients who underwent primary unilateral inguinal hernia repair (IHR) in an outpatient setting between January 2015 and December 2021 were queried from the MerativeTM MarketScan® Research Databases. Reoperation for IHR within two years was compared across surgical approaches: Open (O-IHR), Laparoscopic (L-IHR), and Robotic (R-IHR). Reoperations were further categorized and analyzed separately for recurrent and non-recurrent IHR. Secondary outcomes included all-cause total healthcare expenditures, assessed during the index operation and up to two years postoperatively, based on combined insurer and patient payments. A 1:1 propensity score matching approach was applied, with Cox proportional hazards regression used to analyze reoperation risk, and generalized linear regression models employed to evaluate expenditures.
Results: A total of 73,870 patients undergoing IHR (39,591 [53.6%] O-IHR, 30,858 [41.8%] L-IHR, and 3,421 [4.6%] R-IHR) were included. As compared to O-IHR, any IHR reoperation risk at 2-years was about 42% lower with R-IHR (HR = 0.58, p = 0.002) and about 16% lower with L-IHR (HR= 0.84, p < .001). As compared to O-IHR, total expenditure for the index surgery was approximately $3,391 higher with L-IHR (p < .001) and $4,137 higher with R-IHR (p < .001). R-IHR had about $615 higher index expenditure than L-IHR (p = 0.004).
Conclusion: The current study demonstrates that robotic IHR is associated with a lower risk of reoperations at 2 years after an initial repair as compared to L-IHR and O-IHR, but higher index expenditure in the outpatient setting for an economically active population.
{"title":"Metachronous reoperation for recurrent and non-recurrent inguinal hernia after primary unilateral inguinal hernia repair: propensity score matched analysis of large US claims database.","authors":"Luis Arias-Espinosa, Gediwon Milky, Hannah Bossie, Gabriele Barrocas, Heather Atchison, I-Fan Shih, Flavio Malcher","doi":"10.1007/s10029-025-03518-1","DOIUrl":"10.1007/s10029-025-03518-1","url":null,"abstract":"<p><strong>Introduction: </strong>Inguinal hernia is a common occurrence affecting one in four men. Recurrence is a major clinical pitfall that affects about 10% of patients with increased recurrence and postoperative complications after a revision repair. Reoperation due to metachronous contralateral inguinal hernia is another possible outcome. The impact of minimally invasive surgery (MIS) techniques on inguinal hernia recurrence rates as compared to open surgery is less clear and further confounded by the adoption of robotic approaches. The aim of this study was to compare reoperation rates.</p><p><strong>Methods: </strong>Adult patients who underwent primary unilateral inguinal hernia repair (IHR) in an outpatient setting between January 2015 and December 2021 were queried from the Merative<sup>TM</sup> MarketScan® Research Databases. Reoperation for IHR within two years was compared across surgical approaches: Open (O-IHR), Laparoscopic (L-IHR), and Robotic (R-IHR). Reoperations were further categorized and analyzed separately for recurrent and non-recurrent IHR. Secondary outcomes included all-cause total healthcare expenditures, assessed during the index operation and up to two years postoperatively, based on combined insurer and patient payments. A 1:1 propensity score matching approach was applied, with Cox proportional hazards regression used to analyze reoperation risk, and generalized linear regression models employed to evaluate expenditures.</p><p><strong>Results: </strong>A total of 73,870 patients undergoing IHR (39,591 [53.6%] O-IHR, 30,858 [41.8%] L-IHR, and 3,421 [4.6%] R-IHR) were included. As compared to O-IHR, any IHR reoperation risk at 2-years was about 42% lower with R-IHR (HR = 0.58, p = 0.002) and about 16% lower with L-IHR (HR= 0.84, p < .001). As compared to O-IHR, total expenditure for the index surgery was approximately $3,391 higher with L-IHR (p < .001) and $4,137 higher with R-IHR (p < .001). R-IHR had about $615 higher index expenditure than L-IHR (p = 0.004).</p><p><strong>Conclusion: </strong>The current study demonstrates that robotic IHR is associated with a lower risk of reoperations at 2 years after an initial repair as compared to L-IHR and O-IHR, but higher index expenditure in the outpatient setting for an economically active population.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"25"},"PeriodicalIF":2.4,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12664852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145632143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1007/s10029-025-03499-1
Kristian Als Nielsen, Alexandros Valorenzos, Karsten Kaiser, Cathrine Häbel Frandsen, Per Helligsø, Sofie Ronja Petersen, Mark Bremholm Ellebaek, Michael Festersen Nielsen
Purpose: The use of robotic-assisted ventral hernia repair (rVHR) has expanded rapidly, but its economic viability remains debated. This study aimed to provide a transparent cost analysis of rVHR compared with open ventral hernia repair (oVHR), and to identify patient subgroups where rVHR may represent a cost-effective alternative.
Methods: Patients with midline ventral hernias were randomized to rVHR or oVHR. A detailed bottom-up costing approach was applied, including preoperative, intraoperative, hospitalization, and post-hospitalization costs, as well as capital and maintenance costs of the robotic platform. Group-specific mean costs were estimated using log-linear regression models. Cost-consequence and cost-effectiveness analyses were performed, and an interaction model was used to explore cost differences in relation to hernia defect size.
Results: Fifty-six patients were included (29 rVHR, 27 oVHR). Mean total hospital costs were significantly higher for rVHR (€3,539) compared with oVHR (€1,696; cost ratio 2.09, p <0.001). Instrumentation and consumables accounted for the largest share of rVHR costs, while hospitalization represented the largest component in oVHR. Modeling suggested a potential crossover point at a defect size of 56 cm², beyond which rVHR could become relatively more cost-effective. The cost-effectiveness analysis showed that robotic-assisted surgery required an additional €1,149 to reduce hospital stay by one day.
Conclusion: Robotic-assisted ventral hernia repair is associated with substantially higher costs than open repair in our setting. However, rVHR may represent a more cost-effective strategy for larger or more complex hernias, supporting selective use based on patient characteristics and institutional resources.
{"title":"Robotic-assisted ventral hernia repair - a detailed economic evaluation: is it worth it?","authors":"Kristian Als Nielsen, Alexandros Valorenzos, Karsten Kaiser, Cathrine Häbel Frandsen, Per Helligsø, Sofie Ronja Petersen, Mark Bremholm Ellebaek, Michael Festersen Nielsen","doi":"10.1007/s10029-025-03499-1","DOIUrl":"10.1007/s10029-025-03499-1","url":null,"abstract":"<p><strong>Purpose: </strong>The use of robotic-assisted ventral hernia repair (rVHR) has expanded rapidly, but its economic viability remains debated. This study aimed to provide a transparent cost analysis of rVHR compared with open ventral hernia repair (oVHR), and to identify patient subgroups where rVHR may represent a cost-effective alternative.</p><p><strong>Methods: </strong>Patients with midline ventral hernias were randomized to rVHR or oVHR. A detailed bottom-up costing approach was applied, including preoperative, intraoperative, hospitalization, and post-hospitalization costs, as well as capital and maintenance costs of the robotic platform. Group-specific mean costs were estimated using log-linear regression models. Cost-consequence and cost-effectiveness analyses were performed, and an interaction model was used to explore cost differences in relation to hernia defect size.</p><p><strong>Results: </strong>Fifty-six patients were included (29 rVHR, 27 oVHR). Mean total hospital costs were significantly higher for rVHR (€3,539) compared with oVHR (€1,696; cost ratio 2.09, p <0.001). Instrumentation and consumables accounted for the largest share of rVHR costs, while hospitalization represented the largest component in oVHR. Modeling suggested a potential crossover point at a defect size of 56 cm², beyond which rVHR could become relatively more cost-effective. The cost-effectiveness analysis showed that robotic-assisted surgery required an additional €1,149 to reduce hospital stay by one day.</p><p><strong>Conclusion: </strong>Robotic-assisted ventral hernia repair is associated with substantially higher costs than open repair in our setting. However, rVHR may represent a more cost-effective strategy for larger or more complex hernias, supporting selective use based on patient characteristics and institutional resources.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"24"},"PeriodicalIF":2.4,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12660387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145632112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03523-4
Maria Jose Gomez-Jurado, Mireia Verdaguer-Tremolosa, Victor Rodrigues-Gonçalves, Pilar Martínez-López, María Martínez-López, Meritxell Pera, Mar Dalmau, Manuel López-Cano
Purpose: To evaluate short and long-term outcomes of bilateral groin hernia (BGH) repair using an open preperitoneal approach (OPA) compared to minimally invasive surgery (MIS) in ambulatory surgery.
Methods: A retrospective cohort study was conducted including patients undergoing ambulatory BGH repair between 2010 and 2018 at Vall d'Hebron University Hospital (Barcelona) using either OPA (a modified Wantz technique) or MIS [transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP)]. Demographic, perioperative, and postoperative data were analysed. Chronic postoperative inguinal pain (CPIP) was assessed at two time points: early (3-12 months) and late (> 12 months postoperatively). Long-term follow-up was conducted through structured telephone interviews using the Hernia Recurrence Inventory survey. Multivariate logistic regression and ROC analysis were used to identify predictors of CPIP.
Results: A total of 244 patients (488 hernias) met the inclusion criteria, with a median follow-up of 116 months. OPA patients were older and had more comorbidities (P < 0.001). Operative time was shorter in the OPA group (median 70 vs. 110 min; P < 0.001). No significant differences were found in recurrence rates or surgical site occurrences. Multivariate analysis showed that OPA was independently associated with a lower risk of CPIP between 3-12 months postoperatively (OR 0.091, P < 0.001) compared to MIS. At long-term follow-up, higher Body Mass Index (BMI) was the only factor associated with persistent pain (OR 1.2, P = 0.024).
Conclusion: OPA is a safe and effective technique for BGH repair, offering shorter operative times and lower risk of CPIP between 3-12 months postoperatively compared to MIS, while maintaining comparable long-term outcomes (> 12 months).
{"title":"Ambulatory bilateral groin hernia repair: open preperitoneal versus laparoscopic outcomes.","authors":"Maria Jose Gomez-Jurado, Mireia Verdaguer-Tremolosa, Victor Rodrigues-Gonçalves, Pilar Martínez-López, María Martínez-López, Meritxell Pera, Mar Dalmau, Manuel López-Cano","doi":"10.1007/s10029-025-03523-4","DOIUrl":"10.1007/s10029-025-03523-4","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate short and long-term outcomes of bilateral groin hernia (BGH) repair using an open preperitoneal approach (OPA) compared to minimally invasive surgery (MIS) in ambulatory surgery.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted including patients undergoing ambulatory BGH repair between 2010 and 2018 at Vall d'Hebron University Hospital (Barcelona) using either OPA (a modified Wantz technique) or MIS [transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP)]. Demographic, perioperative, and postoperative data were analysed. Chronic postoperative inguinal pain (CPIP) was assessed at two time points: early (3-12 months) and late (> 12 months postoperatively). Long-term follow-up was conducted through structured telephone interviews using the Hernia Recurrence Inventory survey. Multivariate logistic regression and ROC analysis were used to identify predictors of CPIP.</p><p><strong>Results: </strong>A total of 244 patients (488 hernias) met the inclusion criteria, with a median follow-up of 116 months. OPA patients were older and had more comorbidities (P < 0.001). Operative time was shorter in the OPA group (median 70 vs. 110 min; P < 0.001). No significant differences were found in recurrence rates or surgical site occurrences. Multivariate analysis showed that OPA was independently associated with a lower risk of CPIP between 3-12 months postoperatively (OR 0.091, P < 0.001) compared to MIS. At long-term follow-up, higher Body Mass Index (BMI) was the only factor associated with persistent pain (OR 1.2, P = 0.024).</p><p><strong>Conclusion: </strong>OPA is a safe and effective technique for BGH repair, offering shorter operative times and lower risk of CPIP between 3-12 months postoperatively compared to MIS, while maintaining comparable long-term outcomes (> 12 months).</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"17"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12644117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145586722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03501-w
Marina Eguchi, Thiago Souza E Silva Silva, Elisa Guimarães Forchezatto, Yasmin Biscola da Cruz, Vitor Neves, Denise Padilha, Diego Camacho, Leandro Totti Cavazzola, Diego L Lima
Aim: More than one-third of inguinal hernias are asymptomatic, and performing surgery in the absence or presence of mild symptoms remains a point of concern for many surgeons. This study aims to evaluate whether watchful waiting (WW) is a viable management strategy for asymptomatic and mildly symptomatic inguinal hernias by comparing its outcomes to early surgical repair. To broaden the scope of existing evidence, we included both recent randomized controlled trials and observational studies.
Material and methods: PubMed, Cochrane Central, and EMBASE were searched for studies comparing early repair and WW in patients with asymptomatic or mildly symptomatic inguinal hernias. The primary outcomes assessed were the rate of crossover from WW to surgery, reasons for crossover, and the presence of pain in both groups. Secondary outcomes included quality of life (QoL) and hernia recurrence. A Kaplan-Meier failure function curve was constructed to estimate time from study enrollment to crossover.
Results: Among 619 screened studies, 12 met the inclusion criteria, covering 1,755 patients (748 (42.6%) in early surgical intervention and 1,007 [57.4%] in the WW). Among WW patients, 477 (27.1%) eventually crossed over to surgery, with crossover rates ranging from 6.1% (Patti 2014) to 75.4% (Chung 2011). Approximately 50% of WW patients required surgery within five years. The most reported reason for crossover was pain (65%), followed by impaired quality of life (16%), bowel-related symptoms such as incarceration or strangulation (8.5%), hernia volume progression (3%), and other or unspecified causes (7.5%). Pain was the most consistent patient-specific predictor of crossover to surgery.
Conclusion: WW appears to be a viable and safe approach with low complications rates for patients with asymptomatic inguinal hernias. However, long-term data show that approximately 50% of patients cross over to surgery within five years, and this proportion exceeds 96% by 12 years. Ultimately, the decision between WW and early surgical intervention should be guided by shared decision-making, considering patient values, symptom burden, comorbidities, and life expectancy.
{"title":"Watchful waiting vs. early repair for asymptomatic and mildly symptomatic inguinal hernia - silent hernia, loud debate: a qualitative systematic review.","authors":"Marina Eguchi, Thiago Souza E Silva Silva, Elisa Guimarães Forchezatto, Yasmin Biscola da Cruz, Vitor Neves, Denise Padilha, Diego Camacho, Leandro Totti Cavazzola, Diego L Lima","doi":"10.1007/s10029-025-03501-w","DOIUrl":"10.1007/s10029-025-03501-w","url":null,"abstract":"<p><strong>Aim: </strong>More than one-third of inguinal hernias are asymptomatic, and performing surgery in the absence or presence of mild symptoms remains a point of concern for many surgeons. This study aims to evaluate whether watchful waiting (WW) is a viable management strategy for asymptomatic and mildly symptomatic inguinal hernias by comparing its outcomes to early surgical repair. To broaden the scope of existing evidence, we included both recent randomized controlled trials and observational studies.</p><p><strong>Material and methods: </strong>PubMed, Cochrane Central, and EMBASE were searched for studies comparing early repair and WW in patients with asymptomatic or mildly symptomatic inguinal hernias. The primary outcomes assessed were the rate of crossover from WW to surgery, reasons for crossover, and the presence of pain in both groups. Secondary outcomes included quality of life (QoL) and hernia recurrence. A Kaplan-Meier failure function curve was constructed to estimate time from study enrollment to crossover.</p><p><strong>Results: </strong>Among 619 screened studies, 12 met the inclusion criteria, covering 1,755 patients (748 (42.6%) in early surgical intervention and 1,007 [57.4%] in the WW). Among WW patients, 477 (27.1%) eventually crossed over to surgery, with crossover rates ranging from 6.1% (Patti 2014) to 75.4% (Chung 2011). Approximately 50% of WW patients required surgery within five years. The most reported reason for crossover was pain (65%), followed by impaired quality of life (16%), bowel-related symptoms such as incarceration or strangulation (8.5%), hernia volume progression (3%), and other or unspecified causes (7.5%). Pain was the most consistent patient-specific predictor of crossover to surgery.</p><p><strong>Conclusion: </strong>WW appears to be a viable and safe approach with low complications rates for patients with asymptomatic inguinal hernias. However, long-term data show that approximately 50% of patients cross over to surgery within five years, and this proportion exceeds 96% by 12 years. Ultimately, the decision between WW and early surgical intervention should be guided by shared decision-making, considering patient values, symptom burden, comorbidities, and life expectancy.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"19"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145587141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03539-w
Wendy Wang, Javairia Haq, Em Long-Mills, Dmitry Tumin, Maryna Chumakova-Orin
Purpose: Pre-existing comorbidities may negatively impact surgical outcomes, yet risk profiles based on combinations of comorbidities are underutilized. We aimed to identify comorbidity clusters associated with adverse surgical outcomes after inguinal or ventral hernia repair.
Methods: We performed a retrospective cohort study using the ACS-NSQIP database (2016-2023). Adults undergoing elective inguinal or ventral hernia repair were identified using CPT and ICD-10 codes. Latent class analysis (LCA) identified subgroups of patients who shared similar patterns of comorbidities. Outcomes included postoperative complications, hospital length of stay, and 30-day mortality.
Results: Among 224,522 patients, LCA identified six profiles: no comorbidities, smoking, bleeding disorder or congestive heart failure (CHF), obesity with diabetes or smoking, obesity without diabetes or smoking, and hypertension. Compared with no comorbidities, risk of complications was higher in the smoking (OR 1.32, 95% CI 1.18-1.49), bleeding disorder or CHF (OR 1.68, 95% CI 1.23-2.29), obesity with diabetes or smoking (OR 1.41, 95% CI 1.25-1.58), obesity without diabetes or smoking (OR 1.17, 95% CI 1.06-1.29), and hypertension (OR 1.16, 95% CI 1.05-1.28) clusters. These clusters also had longer hospital stays compared to patients with no comorbidities. 30-day mortality was significantly increased in the "bleeding disorder or CHF" (OR 3.22, 95% CI 1.52-6.84) and hypertension (OR 1.66, 95% CI 1.09-2.54) clusters.
Conclusion: Distinct comorbidity clusters predict complications, prolonged hospitalization, and mortality following hernia repair. Incorporating comorbidity profiles into preoperative risk stratification may enhance surgical decision-making, allow targeted interventions, and improve outcomes in high-risk patients.
目的:先前存在的合并症可能会对手术结果产生负面影响,但基于合并症组合的风险概况尚未得到充分利用。我们的目的是确定与腹股沟或腹疝修补术后不良手术结果相关的合并症群。方法:采用ACS-NSQIP数据库(2016-2023)进行回顾性队列研究。采用CPT和ICD-10编码对接受择期腹股沟或腹疝修补术的成人进行鉴定。潜在分类分析(LCA)确定了具有相似合并症模式的患者亚组。结果包括术后并发症、住院时间和30天死亡率。结果:在224,522例患者中,LCA确定了6个特征:无合并症、吸烟、出血性疾病或充血性心力衰竭(CHF)、肥胖合并糖尿病或吸烟、肥胖非糖尿病或吸烟和高血压。与无合并症相比,吸烟组(OR 1.32, 95% CI 1.18-1.49)、出血性疾病或CHF组(OR 1.68, 95% CI 1.23-2.29)、肥胖合并糖尿病或吸烟组(OR 1.41, 95% CI 1.25-1.58)、肥胖合并糖尿病或吸烟组(OR 1.17, 95% CI 1.06-1.29)和高血压组(OR 1.16, 95% CI 1.05-1.28)的并发症风险更高。与无合并症的患者相比,这些患者的住院时间也更长。“出血性疾病或CHF”(or 3.22, 95% CI 1.52-6.84)和高血压(or 1.66, 95% CI 1.09-2.54)组的30天死亡率显著增加。结论:不同的合并症簇预示着疝修补术后的并发症、住院时间延长和死亡率。将合并症资料纳入术前风险分层可以加强手术决策,允许有针对性的干预,并改善高危患者的预后。
{"title":"Correlation between inguinal and ventral hernia repair outcomes and pre-existing comorbidity clusters: ACS-NSQIP study.","authors":"Wendy Wang, Javairia Haq, Em Long-Mills, Dmitry Tumin, Maryna Chumakova-Orin","doi":"10.1007/s10029-025-03539-w","DOIUrl":"10.1007/s10029-025-03539-w","url":null,"abstract":"<p><strong>Purpose: </strong>Pre-existing comorbidities may negatively impact surgical outcomes, yet risk profiles based on combinations of comorbidities are underutilized. We aimed to identify comorbidity clusters associated with adverse surgical outcomes after inguinal or ventral hernia repair.</p><p><strong>Methods: </strong>We performed a retrospective cohort study using the ACS-NSQIP database (2016-2023). Adults undergoing elective inguinal or ventral hernia repair were identified using CPT and ICD-10 codes. Latent class analysis (LCA) identified subgroups of patients who shared similar patterns of comorbidities. Outcomes included postoperative complications, hospital length of stay, and 30-day mortality.</p><p><strong>Results: </strong>Among 224,522 patients, LCA identified six profiles: no comorbidities, smoking, bleeding disorder or congestive heart failure (CHF), obesity with diabetes or smoking, obesity without diabetes or smoking, and hypertension. Compared with no comorbidities, risk of complications was higher in the smoking (OR 1.32, 95% CI 1.18-1.49), bleeding disorder or CHF (OR 1.68, 95% CI 1.23-2.29), obesity with diabetes or smoking (OR 1.41, 95% CI 1.25-1.58), obesity without diabetes or smoking (OR 1.17, 95% CI 1.06-1.29), and hypertension (OR 1.16, 95% CI 1.05-1.28) clusters. These clusters also had longer hospital stays compared to patients with no comorbidities. 30-day mortality was significantly increased in the \"bleeding disorder or CHF\" (OR 3.22, 95% CI 1.52-6.84) and hypertension (OR 1.66, 95% CI 1.09-2.54) clusters.</p><p><strong>Conclusion: </strong>Distinct comorbidity clusters predict complications, prolonged hospitalization, and mortality following hernia repair. Incorporating comorbidity profiles into preoperative risk stratification may enhance surgical decision-making, allow targeted interventions, and improve outcomes in high-risk patients.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"23"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145587075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03491-9
Lei Guan, Yusheng Nie, Xiaoli Liu, Qiuyue Ma, Huiqi Yang, Jie Chen
Purpose: The synthetic meshes were widely applied in laparoscopic repair of hiatal hernia. In contrast, there were few researches on the application of biological meshes and it's clinical effects needed to be further verified especially in the giant hiatal hernia. Our aim of this study was to assess the clinical outcomes and safety of biological versus synthetic meshes in a short-term comparative period.
Methods: This prospective cohort study of 174 patients with 87 patients in each group underwent laparoscopic repair of hiatal hernia from April 2022 to February 2024 in single‑center. The biological mesh group and the synthetic mesh group were respectively repaired with Small Intestinal Submucosa (SIS) mesh and anti-adhesion polypropylene mesh for crura reinforcement. The general baseline characteristics, perioperative data, complications, recurrence rate, symptom and quality of life improvement data (the Visual Analog Scale, VAS and the Short Form 36 Health Survey, SF-36), satisfaction were collected. Follow-up data were collected at 6 and 12 months postoperatively.
Results: In comparison between the two groups, no significant differences were observed in the general baseline characteristics including sex, age, BMI, chronic disease, preoperative PPI use, preoperative anaemia (P > 0.05) and perioperative data including operation times, blooding loss, defect length, defect width and mesh-related reactions (extensive perimesh fluid collection and postoperative fever) (P > 0.05). The postoperative hospital stay of the biological group was longer than the synthetic group (4.5 ± 1.6vs. 4.1 ± 1.1; P = 0.111) with no statistical difference. There was no mortality and mesh-related complications such as dysphagia, mesh infection, esophageal erosion, esophageal perforation in each group. Both groups demonstrated similar and significant improvement in quality of life scores and symptoms scores with high satisfaction at 6 and 12 months postoperatively (P > 0.05). The recurrence rate was 0% in the biological mesh group and 1.1% in the synthetic mesh group at 6 months (P = 0.316). At 12 months, the recurrence rate was 1.1% in each group (P = 1.000). All recurrent cases were diagnosed as type IV hiatal hernia preoperatively.
Conclusions: Biological and synthetic meshes demonstrated similar and satisfactory results in clinical effect and improvement of quality of life with low recurrence and complication rates in laparoscopic hiatal hernia repair. The biological mesh is effective and safe in the repair of giant hiatal hernia. Compared with synthetic meshes, the application of biological meshes does not increase the postoperative hospital stay due to the mesh-related reactions in a short-term comparative period.
{"title":"Prospective cohort study of biological versus and synthetic meshes for laparoscopic repair of hiatal hernia.","authors":"Lei Guan, Yusheng Nie, Xiaoli Liu, Qiuyue Ma, Huiqi Yang, Jie Chen","doi":"10.1007/s10029-025-03491-9","DOIUrl":"10.1007/s10029-025-03491-9","url":null,"abstract":"<p><strong>Purpose: </strong>The synthetic meshes were widely applied in laparoscopic repair of hiatal hernia. In contrast, there were few researches on the application of biological meshes and it's clinical effects needed to be further verified especially in the giant hiatal hernia. Our aim of this study was to assess the clinical outcomes and safety of biological versus synthetic meshes in a short-term comparative period.</p><p><strong>Methods: </strong>This prospective cohort study of 174 patients with 87 patients in each group underwent laparoscopic repair of hiatal hernia from April 2022 to February 2024 in single‑center. The biological mesh group and the synthetic mesh group were respectively repaired with Small Intestinal Submucosa (SIS) mesh and anti-adhesion polypropylene mesh for crura reinforcement. The general baseline characteristics, perioperative data, complications, recurrence rate, symptom and quality of life improvement data (the Visual Analog Scale, VAS and the Short Form 36 Health Survey, SF-36), satisfaction were collected. Follow-up data were collected at 6 and 12 months postoperatively.</p><p><strong>Results: </strong>In comparison between the two groups, no significant differences were observed in the general baseline characteristics including sex, age, BMI, chronic disease, preoperative PPI use, preoperative anaemia (P > 0.05) and perioperative data including operation times, blooding loss, defect length, defect width and mesh-related reactions (extensive perimesh fluid collection and postoperative fever) (P > 0.05). The postoperative hospital stay of the biological group was longer than the synthetic group (4.5 ± 1.6vs. 4.1 ± 1.1; P = 0.111) with no statistical difference. There was no mortality and mesh-related complications such as dysphagia, mesh infection, esophageal erosion, esophageal perforation in each group. Both groups demonstrated similar and significant improvement in quality of life scores and symptoms scores with high satisfaction at 6 and 12 months postoperatively (P > 0.05). The recurrence rate was 0% in the biological mesh group and 1.1% in the synthetic mesh group at 6 months (P = 0.316). At 12 months, the recurrence rate was 1.1% in each group (P = 1.000). All recurrent cases were diagnosed as type IV hiatal hernia preoperatively.</p><p><strong>Conclusions: </strong>Biological and synthetic meshes demonstrated similar and satisfactory results in clinical effect and improvement of quality of life with low recurrence and complication rates in laparoscopic hiatal hernia repair. The biological mesh is effective and safe in the repair of giant hiatal hernia. Compared with synthetic meshes, the application of biological meshes does not increase the postoperative hospital stay due to the mesh-related reactions in a short-term comparative period.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"20"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145587026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03528-z
Hector Guadalajara, Marius Kaser, Miguel León Arellano, Montiel Jiménez Fuertes, Ignacio Mahíllo-Fernández, Damián García-Olmo
{"title":"Barbed versus conventional sutures and the risk of abdominal wall dehiscence after laparotomy: a multicenter retrospective cohort study.","authors":"Hector Guadalajara, Marius Kaser, Miguel León Arellano, Montiel Jiménez Fuertes, Ignacio Mahíllo-Fernández, Damián García-Olmo","doi":"10.1007/s10029-025-03528-z","DOIUrl":"https://doi.org/10.1007/s10029-025-03528-z","url":null,"abstract":"","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"21"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145586964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1007/s10029-025-03535-0
Qin Ma, Xi Li, Jinming Xu, Jinjie Du
Objective: To evaluate the efficacy and safety of different methods of managing the distal hernia sac in preventing seroma after laparoscopic transabdominal preperitoneal repair (TAPP) for large indirect inguinal hernias.
Methods: A retrospective analysis was conducted on 163 male patients with unilateral large indirect inguinal hernias (hernia sac diameter > 5 cm) who underwent TAPP at the Department of Gastrointestinal Surgery, Fuling Hospital of Chongqing University between January 2020 and January 2025. Based on the method of hernia sac management, patients were divided into three groups: Group A (n = 38) underwent complete dissection of the hernia sac; Group B (n = 61) underwent transection and abandonment of the distal sac; Group C (n = 64) underwent midline transection of the lateral hernia sac combined with lateral fixation of the residual stump. Perioperative indicators, postoperative VAS scores, and complication rates were compared among the groups.
Results: All 163 patients successfully completed the surgery. Operative time was significantly longer in Group A (94.16 ± 21.93 min) compared to Groups B (80.59 ± 27.00 min) and C (93.97 ± 23.49 min) (P = 0.027), whereas no significant difference was detected between Groups B and C. The time required for hernia sac management also differed significantly across groups (P < 0.001), being longest in Group A, followed by Group C, and shortest in Group B. In terms of hospital stay, Group B (6 [5, 7] days) stayed significantly longer than both Group A and Group C (both 5 [4, 7] days) (P = 0.005). The incidence of seroma was significantly higher in Group B (18.03%) than in Group A (5.26%) and Group C (4.69%) (P = 0.035). Multivariable logistic regression further identified the surgical technique used in Group B as an independent risk factor for seroma (aOR: 5.47, 95% CI: 1.35-22.13, P = 0.017). The incidences of scrotal hematoma and ischemic orchitis were significantly higher in Group A than in the other two groups (P = 0.012 for both). There were no significant differences among the three groups in postoperative VAS scores, intraoperative blood loss, urinary retention, infection, recurrence, or chronic pain rates.
Conclusion: In this study, midline transection of the lateral hernia sac combined with lateral stump fixation was associated with a lower incidence of seroma after TAPP for large indirect inguinal hernias, without a significant increase in the risks of postoperative pain, scrotal hematoma, ischemic orchitis, infection, recurrence, or other complications.
{"title":"Different methods of managing the distal hernia sac to prevent seroma after laparoscopic repair of large indirect inguinal hernias: a real-world study.","authors":"Qin Ma, Xi Li, Jinming Xu, Jinjie Du","doi":"10.1007/s10029-025-03535-0","DOIUrl":"10.1007/s10029-025-03535-0","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of different methods of managing the distal hernia sac in preventing seroma after laparoscopic transabdominal preperitoneal repair (TAPP) for large indirect inguinal hernias.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 163 male patients with unilateral large indirect inguinal hernias (hernia sac diameter > 5 cm) who underwent TAPP at the Department of Gastrointestinal Surgery, Fuling Hospital of Chongqing University between January 2020 and January 2025. Based on the method of hernia sac management, patients were divided into three groups: Group A (n = 38) underwent complete dissection of the hernia sac; Group B (n = 61) underwent transection and abandonment of the distal sac; Group C (n = 64) underwent midline transection of the lateral hernia sac combined with lateral fixation of the residual stump. Perioperative indicators, postoperative VAS scores, and complication rates were compared among the groups.</p><p><strong>Results: </strong>All 163 patients successfully completed the surgery. Operative time was significantly longer in Group A (94.16 ± 21.93 min) compared to Groups B (80.59 ± 27.00 min) and C (93.97 ± 23.49 min) (P = 0.027), whereas no significant difference was detected between Groups B and C. The time required for hernia sac management also differed significantly across groups (P < 0.001), being longest in Group A, followed by Group C, and shortest in Group B. In terms of hospital stay, Group B (6 [5, 7] days) stayed significantly longer than both Group A and Group C (both 5 [4, 7] days) (P = 0.005). The incidence of seroma was significantly higher in Group B (18.03%) than in Group A (5.26%) and Group C (4.69%) (P = 0.035). Multivariable logistic regression further identified the surgical technique used in Group B as an independent risk factor for seroma (aOR: 5.47, 95% CI: 1.35-22.13, P = 0.017). The incidences of scrotal hematoma and ischemic orchitis were significantly higher in Group A than in the other two groups (P = 0.012 for both). There were no significant differences among the three groups in postoperative VAS scores, intraoperative blood loss, urinary retention, infection, recurrence, or chronic pain rates.</p><p><strong>Conclusion: </strong>In this study, midline transection of the lateral hernia sac combined with lateral stump fixation was associated with a lower incidence of seroma after TAPP for large indirect inguinal hernias, without a significant increase in the risks of postoperative pain, scrotal hematoma, ischemic orchitis, infection, recurrence, or other complications.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"22"},"PeriodicalIF":2.4,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145586977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}