Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03553-y
Haiye Shen, Dominic Farris, David L Sanders, Helen Dawes, Sarah E Lamb, John M Findlay
Background: Incisional and non-incisional ventral hernias are common and important causes of symptoms, functional restriction, and complications, with significant potential to impact upon quality of life. The goals of hernia repair are to treat, prevent or improve these. However, outcomes of surgery remain relatively poor with significant gaps within the evidence base, which may be due to inconsistent use of outcome measures. The aim of this study was to appraise outcome reporting in the recent literature of randomized controlled trials (RCTs).
Objectives: This scoping review aimed to map and categorize the outcome measures reported in RCTs of incisional and non-incisional ventral hernia repair.
Eligibility criteria: All RCTs assessing any intervention related to incisional, primary, or recurrent ventral hernia repair between2015 and 2025 were included.
Source of evidence: A literature search was performed of the PubMed, EMBASE (1974 to present), and Cochrane Central Register of Controlled Trials databases in November March 2025.
Charting methods: Data was extracted independently by two reviewers. All outcomes reported by the included studies were identified and recorded.
Results: 118 RCTs were included. Their outcomes were mapped into five main broad categories. The commonest outcomes used were short-term operative complications (72.9%), hernia recurrence (59.3%), pain (57.6%), and quality of life (33.9%). Patient-reported outcomes were measured in 78 (66.1%) randomized controlled trials, of which 15 assessment tools were identified; 11 were generic, and 4were hernia-specific. There was considerable heterogeneity in how and when these endpoints were assessed and defined.
Conclusion: This scoping review found considerable differences in outcome reporting in contemporary RCTs of incisional and non-incisional ventral hernia. These have significant implications for translating evidence into practice, and its synthesis, and support the need for a core outcome set in this field. However, we identified areas such as abdominal wall function which are infrequently reported and require consideration.
{"title":"A scoping review of outcome reporting in randomized controlled trials of incisional and non-incisional ventral hernia repair.","authors":"Haiye Shen, Dominic Farris, David L Sanders, Helen Dawes, Sarah E Lamb, John M Findlay","doi":"10.1007/s10029-025-03553-y","DOIUrl":"10.1007/s10029-025-03553-y","url":null,"abstract":"<p><strong>Background: </strong>Incisional and non-incisional ventral hernias are common and important causes of symptoms, functional restriction, and complications, with significant potential to impact upon quality of life. The goals of hernia repair are to treat, prevent or improve these. However, outcomes of surgery remain relatively poor with significant gaps within the evidence base, which may be due to inconsistent use of outcome measures. The aim of this study was to appraise outcome reporting in the recent literature of randomized controlled trials (RCTs).</p><p><strong>Objectives: </strong>This scoping review aimed to map and categorize the outcome measures reported in RCTs of incisional and non-incisional ventral hernia repair.</p><p><strong>Eligibility criteria: </strong>All RCTs assessing any intervention related to incisional, primary, or recurrent ventral hernia repair between2015 and 2025 were included.</p><p><strong>Source of evidence: </strong>A literature search was performed of the PubMed, EMBASE (1974 to present), and Cochrane Central Register of Controlled Trials databases in November March 2025.</p><p><strong>Charting methods: </strong>Data was extracted independently by two reviewers. All outcomes reported by the included studies were identified and recorded.</p><p><strong>Results: </strong>118 RCTs were included. Their outcomes were mapped into five main broad categories. The commonest outcomes used were short-term operative complications (72.9%), hernia recurrence (59.3%), pain (57.6%), and quality of life (33.9%). Patient-reported outcomes were measured in 78 (66.1%) randomized controlled trials, of which 15 assessment tools were identified; 11 were generic, and 4were hernia-specific. There was considerable heterogeneity in how and when these endpoints were assessed and defined.</p><p><strong>Conclusion: </strong>This scoping review found considerable differences in outcome reporting in contemporary RCTs of incisional and non-incisional ventral hernia. These have significant implications for translating evidence into practice, and its synthesis, and support the need for a core outcome set in this field. However, we identified areas such as abdominal wall function which are infrequently reported and require consideration.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"71"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145989051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03566-7
Claudia Theis, Neophytos Christodoulou, Victor Andrade Nunes, Augusto Graziani E Sousa, Sergio Mazzola Poli de Figueiredo
Purpose: Retromuscular ventral hernia repair (RVHR) is a well-established and increasingly popular technique for mesh placement, offering favorable recurrence and complication rates. However, the role of mesh fixation in RVHR remains unclear, as some have questioned its effect on reducing recurrence and could potentially increase postoperative morbidity. We performed a systematic review and meta-analysis to compare outcomes of RVHR with and without mesh fixation.
Methodology: PubMed, EMBASE, and Cochrane Library were searched through July 2025. Eligible studies included adult patients undergoing open RVHR with or without fixation. Primary outcomes were hernia recurrence and postoperative pain; secondary outcomes included hematoma, seroma, surgical site infection (SSI), reoperation, operative time, length of stay (LOS), and quality of life. Risk of bias was assessed using RoB 2 and ROBINS-I. Random-effects models were used, and heterogeneity was quantified using the I2 statistic.
Results: Six studies (15,106 patients; 3,994 without fixation) met inclusion criteria: two randomized controlled trials and four observational cohorts, including one registry study. Recurrence did not differ between fixation and non-fixation (OR 1.1, 95% CI 0.91-1.34; I2 = 0%). Fixation was associated with significantly worse quality-of-life scores (MD -12.71, 95% CI -16.48 to -8.93; p < 0.001; I2 = 0%) and higher hematoma risk (OR 5.18, 95% CI 1.18-22.68; p = 0.03; I2 = 0%). No significant differences were found for pain, SSI, seroma, reoperation, LOS, or operative time.
Conclusion: Our systematic review and meta-analysis identified no difference in recurrence, pain, SSI, or long-term outcomes between mesh fixation and non-fixation in RVHR. However, fixation was associated with significantly worse quality-of-life scores and a higher risk of hematoma. These findings suggest a selective rather than routine use of mesh fixation in RVHR.
目的:肌肉后腹疝修补术(RVHR)是一种成熟且日益流行的补片放置技术,具有良好的复发率和并发症发生率。然而,补片固定在RVHR中的作用仍不清楚,因为一些人质疑其减少复发的作用,并可能增加术后发病率。我们进行了系统回顾和荟萃分析,以比较有和没有网状物固定的RVHR的结果。方法:检索截止到2025年7月的PubMed、EMBASE和Cochrane图书馆。符合条件的研究包括接受开放性RVHR的成人患者,有或没有固定。主要结局为疝复发和术后疼痛;次要结局包括血肿、血肿、手术部位感染(SSI)、再手术、手术时间、住院时间(LOS)和生活质量。使用rob2和ROBINS-I评估偏倚风险。采用随机效应模型,采用I2统计量对异质性进行量化。结果:6项研究(15106例患者,3994例未固定)符合纳入标准:2项随机对照试验和4项观察性队列,包括1项注册研究。固定和非固定的复发率无差异(OR 1.1, 95% CI 0.91-1.34; I2 = 0%)。固定与较差的生活质量评分相关(MD -12.71, 95% CI -16.48至-8.93;p)结论:我们的系统回顾和荟萃分析发现,在RVHR中,网状固定与非固定在复发、疼痛、SSI或长期结局方面没有差异。然而,固定与较差的生活质量评分和较高的血肿风险相关。这些发现提示在RVHR中选择性而非常规使用网状固定。
{"title":"Is mesh fixation necessary in open retromuscular ventral hernia repair? A meta-analysis.","authors":"Claudia Theis, Neophytos Christodoulou, Victor Andrade Nunes, Augusto Graziani E Sousa, Sergio Mazzola Poli de Figueiredo","doi":"10.1007/s10029-025-03566-7","DOIUrl":"10.1007/s10029-025-03566-7","url":null,"abstract":"<p><strong>Purpose: </strong>Retromuscular ventral hernia repair (RVHR) is a well-established and increasingly popular technique for mesh placement, offering favorable recurrence and complication rates. However, the role of mesh fixation in RVHR remains unclear, as some have questioned its effect on reducing recurrence and could potentially increase postoperative morbidity. We performed a systematic review and meta-analysis to compare outcomes of RVHR with and without mesh fixation.</p><p><strong>Methodology: </strong>PubMed, EMBASE, and Cochrane Library were searched through July 2025. Eligible studies included adult patients undergoing open RVHR with or without fixation. Primary outcomes were hernia recurrence and postoperative pain; secondary outcomes included hematoma, seroma, surgical site infection (SSI), reoperation, operative time, length of stay (LOS), and quality of life. Risk of bias was assessed using RoB 2 and ROBINS-I. Random-effects models were used, and heterogeneity was quantified using the I2 statistic.</p><p><strong>Results: </strong>Six studies (15,106 patients; 3,994 without fixation) met inclusion criteria: two randomized controlled trials and four observational cohorts, including one registry study. Recurrence did not differ between fixation and non-fixation (OR 1.1, 95% CI 0.91-1.34; I2 = 0%). Fixation was associated with significantly worse quality-of-life scores (MD -12.71, 95% CI -16.48 to -8.93; p < 0.001; I2 = 0%) and higher hematoma risk (OR 5.18, 95% CI 1.18-22.68; p = 0.03; I2 = 0%). No significant differences were found for pain, SSI, seroma, reoperation, LOS, or operative time.</p><p><strong>Conclusion: </strong>Our systematic review and meta-analysis identified no difference in recurrence, pain, SSI, or long-term outcomes between mesh fixation and non-fixation in RVHR. However, fixation was associated with significantly worse quality-of-life scores and a higher risk of hematoma. These findings suggest a selective rather than routine use of mesh fixation in RVHR.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"69"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03573-8
Anshumi Desai, Gabriel De la Cruz Ku, Jiddu Guart, Alba Zevallos, Martin Hemeryth, Flavia Rioja, Joseph M Escandón, Sarah Roberts, Jose Luis Guillermo Barrueto-Deza, Bryan Valcarcel, Camila Franco
Introduction: Parastomal hernias (PSHs) significantly impact the quality of life and pose risks including obstruction and stoma dysfunction. Minimally invasive approaches, particularly robotic surgery, are increasingly employed for elective PSH repairs, yet comparative outcomes remain insufficiently studied. This study evaluated short-term outcomes comparing robotic and open PSH repairs.
Methods: A retrospective cohort analysis was conducted using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Patients undergoing elective open, laparoscopic, or robotic PSH repairs were identified. Propensity score matching was used to balance baseline characteristics, and multivariate logistic regression identified independent predictors of complications.
Results: Of 1,322 patients, 734 (55.5%) underwent open repair, 408 (30.9%) robotic, and 180 (13.6%) laparoscopic. After matching 808 patients (404 robotic, 404 open), robotic repair significantly reduced overall complications (50 patients, 12.4% vs. 101 patients, 25.0%; p < 0.001), surgical complications (22 patients, 5.4% vs. 45 patients, 11.1%; p = 0.003), medical complications (36 patients, 8.9% vs. 66 patients, 16.3%; p = 0.001), superficial surgical site infections (8 patients, 2.0% vs. 26 patients, 6.4%; p = 0.002), and bleeding requiring transfusion (2 patients, 0.5% vs. 13 patients, 3.2%; p = 0.004). Robotic surgery also reduced length of stay (3.26 days vs. 6.08 days; p < 0.001). Multivariate analysis confirmed robotic technique as an independent protective factor against postoperative complications (OR: 0.414; p < 0.001). (OR: 0.414; p < 0.001).
Conclusion: Robotic-assisted PSH repair significantly reduces perioperative morbidity, complication rates, and hospital length of stay compared to open surgery. These results support robotic approaches as preferable for elective PSH repair.
摘要:造口旁疝(PSHs)严重影响患者的生活质量,并存在梗阻和造口功能障碍等风险。微创入路,特别是机器人手术,越来越多地用于选择性PSH修复,但比较结果仍然没有充分的研究。本研究比较了机器人和开放式PSH修复的短期效果。方法:采用美国外科医师学会国家手术质量改进计划(ACS-NSQIP)数据库进行回顾性队列分析。患者接受择期开放、腹腔镜或机器人PSH修复。倾向评分匹配用于平衡基线特征,多变量逻辑回归确定并发症的独立预测因子。结果:在1322例患者中,734例(55.5%)采用开放式修复,408例(30.9%)采用机器人修复,180例(13.6%)采用腹腔镜修复。在匹配808例患者(404例机器人,404例开放)后,机器人修复显着降低了总体并发症(50例,12.4% vs. 101例,25.0%)。结论:与开放手术相比,机器人辅助PSH修复显着降低了围手术期发病率、并发症发生率和住院时间。这些结果支持机器人方法是选择性PSH修复的首选方法。
{"title":"Short-term outcomes and risk factors for complications in robotic versus open parastomal hernia repair: a retrospective propensity score-matched analysis.","authors":"Anshumi Desai, Gabriel De la Cruz Ku, Jiddu Guart, Alba Zevallos, Martin Hemeryth, Flavia Rioja, Joseph M Escandón, Sarah Roberts, Jose Luis Guillermo Barrueto-Deza, Bryan Valcarcel, Camila Franco","doi":"10.1007/s10029-025-03573-8","DOIUrl":"https://doi.org/10.1007/s10029-025-03573-8","url":null,"abstract":"<p><strong>Introduction: </strong>Parastomal hernias (PSHs) significantly impact the quality of life and pose risks including obstruction and stoma dysfunction. Minimally invasive approaches, particularly robotic surgery, are increasingly employed for elective PSH repairs, yet comparative outcomes remain insufficiently studied. This study evaluated short-term outcomes comparing robotic and open PSH repairs.</p><p><strong>Methods: </strong>A retrospective cohort analysis was conducted using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Patients undergoing elective open, laparoscopic, or robotic PSH repairs were identified. Propensity score matching was used to balance baseline characteristics, and multivariate logistic regression identified independent predictors of complications.</p><p><strong>Results: </strong>Of 1,322 patients, 734 (55.5%) underwent open repair, 408 (30.9%) robotic, and 180 (13.6%) laparoscopic. After matching 808 patients (404 robotic, 404 open), robotic repair significantly reduced overall complications (50 patients, 12.4% vs. 101 patients, 25.0%; p < 0.001), surgical complications (22 patients, 5.4% vs. 45 patients, 11.1%; p = 0.003), medical complications (36 patients, 8.9% vs. 66 patients, 16.3%; p = 0.001), superficial surgical site infections (8 patients, 2.0% vs. 26 patients, 6.4%; p = 0.002), and bleeding requiring transfusion (2 patients, 0.5% vs. 13 patients, 3.2%; p = 0.004). Robotic surgery also reduced length of stay (3.26 days vs. 6.08 days; p < 0.001). Multivariate analysis confirmed robotic technique as an independent protective factor against postoperative complications (OR: 0.414; p < 0.001). (OR: 0.414; p < 0.001).</p><p><strong>Conclusion: </strong>Robotic-assisted PSH repair significantly reduces perioperative morbidity, complication rates, and hospital length of stay compared to open surgery. These results support robotic approaches as preferable for elective PSH repair.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"62"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03559-6
Gunnar Nordqvist, Karin Strigård, Jeaneth Johansson, Catharina Gustavsson, Viktor Holmdahl
Aim: The aim of this study was to explore patients' experiences of participation in a preoptimisation programme prior to ventral hernia repair, focusing on the programme's feasibility and patient-perceived potential.
Introduction: Preoptimisation of modifiable risk factors has received growing attention, but little is known about ventral hernia patients' perspectives on such programmes. Understanding patient motivation and perceived barriers is critical for designing effective interventions.
Method: Eight ventral hernia patients participated in a home-based preoptimisation programme lasting at least three weeks. Focus group interviews were conducted and analysed using reflexive thematic analysis.
Results: Participants generally perceived the preoptimisation programme positively. Clear and structured advice was valued, with participants appreciating straightforward instructions on physical activity and lifestyle change. Reported barriers included everyday life circumstances, orthopaedic comorbidities, and in some cases the hernia itself. Patients described perceived positive health effects, including improved fitness, weight loss, and better diabetes control. No adverse effects were raised during the interviews.
Conclusion: This is, to our knowledge, the first qualitative study of pre-optimisation programmes in ventral hernia surgery. As an exploratory, hypothesis-generating study, its findings are shaped by sample size and setting but provide novel insights that complement quantitative research by highlighting patient perspectives. Pre-optimisation programmes appear feasible and meaningful to ventral hernia patients, particularly when supported by clear guidance, structured follow-up, and surgeon involvement. The findings are discussed in the light of Self-Determination Theory, which emphasises internalisation of motivation through autonomy, competence, and relatedness.
{"title":"Potential and feasibility of preoptimisation in ventral hernia repair- a focus group study.","authors":"Gunnar Nordqvist, Karin Strigård, Jeaneth Johansson, Catharina Gustavsson, Viktor Holmdahl","doi":"10.1007/s10029-025-03559-6","DOIUrl":"10.1007/s10029-025-03559-6","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to explore patients' experiences of participation in a preoptimisation programme prior to ventral hernia repair, focusing on the programme's feasibility and patient-perceived potential.</p><p><strong>Introduction: </strong>Preoptimisation of modifiable risk factors has received growing attention, but little is known about ventral hernia patients' perspectives on such programmes. Understanding patient motivation and perceived barriers is critical for designing effective interventions.</p><p><strong>Method: </strong>Eight ventral hernia patients participated in a home-based preoptimisation programme lasting at least three weeks. Focus group interviews were conducted and analysed using reflexive thematic analysis.</p><p><strong>Results: </strong>Participants generally perceived the preoptimisation programme positively. Clear and structured advice was valued, with participants appreciating straightforward instructions on physical activity and lifestyle change. Reported barriers included everyday life circumstances, orthopaedic comorbidities, and in some cases the hernia itself. Patients described perceived positive health effects, including improved fitness, weight loss, and better diabetes control. No adverse effects were raised during the interviews.</p><p><strong>Conclusion: </strong>This is, to our knowledge, the first qualitative study of pre-optimisation programmes in ventral hernia surgery. As an exploratory, hypothesis-generating study, its findings are shaped by sample size and setting but provide novel insights that complement quantitative research by highlighting patient perspectives. Pre-optimisation programmes appear feasible and meaningful to ventral hernia patients, particularly when supported by clear guidance, structured follow-up, and surgeon involvement. The findings are discussed in the light of Self-Determination Theory, which emphasises internalisation of motivation through autonomy, competence, and relatedness.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"66"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03544-z
Michala Klusáček Rampichová, Kateřina Strnadová, M Plencner, L Stanislav, A Litvinec, Z Tonar, T Blassová, M Otáhal, E Filová, D Lukáš, V Jenčová
Purpose: Incisional hernia is a common postoperative complication following abdominal surgery. Despite the use of synthetic meshes, recurrence rates remain high. This study aimed to develop and evaluate a biodegradable, aligned microfibrous scaffold to support wound healing and strengthen abdominal wall repair.
Methods: Scaffolds were fabricated from poly(ε-caprolactone) (PCL) using a controlled fiber-drawing technique to produce highly aligned microfibers with reproducible thickness and architecture. Their biocompatibility was examined in vitro using fibroblasts through adhesion and proliferation assays. For in vivo evaluation, the scaffolds were implanted over standardized abdominal wall incisions in rabbits. After six weeks, the regenerated tissue was harvested for mechanical testing to determine tensile strength and elasticity, while histological and immunohistochemical analyses assessed collagen type I deposition and neovascularization within the scaffold area.
Results: The aligned PCL scaffold promoted strong cell attachment and proliferation in vitro. In vivo, its application significantly increased tensile modulus compared with control wounds. Histological analysis revealed denser and more organized collagen deposition and a higher microvessel density in the scaffold-treated group, indicating enhanced tissue remodeling and vascular integration.
Conclusion: The aligned PCL microfibrous scaffold improved the mechanical and biological quality of the abdominal wall healing in vivo. These results suggest its potential for reducing the formation of incisional hernias and are suitable for further testing leading to use in clinical practice.
{"title":"Enhancing abdominal wall healing using an oriented polycaprolactone microfibrous scaffold prepared using the fiber drawing method: A rabbit model study.","authors":"Michala Klusáček Rampichová, Kateřina Strnadová, M Plencner, L Stanislav, A Litvinec, Z Tonar, T Blassová, M Otáhal, E Filová, D Lukáš, V Jenčová","doi":"10.1007/s10029-025-03544-z","DOIUrl":"10.1007/s10029-025-03544-z","url":null,"abstract":"<p><strong>Purpose: </strong>Incisional hernia is a common postoperative complication following abdominal surgery. Despite the use of synthetic meshes, recurrence rates remain high. This study aimed to develop and evaluate a biodegradable, aligned microfibrous scaffold to support wound healing and strengthen abdominal wall repair.</p><p><strong>Methods: </strong>Scaffolds were fabricated from poly(ε-caprolactone) (PCL) using a controlled fiber-drawing technique to produce highly aligned microfibers with reproducible thickness and architecture. Their biocompatibility was examined in vitro using fibroblasts through adhesion and proliferation assays. For in vivo evaluation, the scaffolds were implanted over standardized abdominal wall incisions in rabbits. After six weeks, the regenerated tissue was harvested for mechanical testing to determine tensile strength and elasticity, while histological and immunohistochemical analyses assessed collagen type I deposition and neovascularization within the scaffold area.</p><p><strong>Results: </strong>The aligned PCL scaffold promoted strong cell attachment and proliferation in vitro. In vivo, its application significantly increased tensile modulus compared with control wounds. Histological analysis revealed denser and more organized collagen deposition and a higher microvessel density in the scaffold-treated group, indicating enhanced tissue remodeling and vascular integration.</p><p><strong>Conclusion: </strong>The aligned PCL microfibrous scaffold improved the mechanical and biological quality of the abdominal wall healing in vivo. These results suggest its potential for reducing the formation of incisional hernias and are suitable for further testing leading to use in clinical practice.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"67"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145989025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03564-9
Shan L Kalmeta, Gustavo Salgado-Garza, Rebecca Prymak, Maggie E Bosley, Vahagn C Nikolian
Purpose: During the COVID-19 pandemic, digital encounters became a crucial means of maintaining access to care amid restrictions on in-person interactions. As these limitations ease, it is essential to evaluate the outcomes of telehealth-based consultations. Before the pandemic, telehealth was predominantly used in postoperative care for surgical populations. This study examines the safety and efficacy of telehealth-based consultations compared to traditional in-person preoperative evaluations for small ventral hernia repair, contributing to the understanding of how telemedicine can be effectively integrated into surgical practices.
Methods: We utilized a prospectively maintained single-center database from a tertiary referral hospital with a specialized hernia and abdominal wall reconstruction team to compare preoperative, intraoperative, and postoperative variables between ventral hernia patients who received telehealth-based (phone or video) consultations and those who had any in-person clinic evaluation.
Results: A total of 187 patients with small (< 4 cm) ventral hernias were evaluated, with 42 (22%) being evaluated entirely through telemedicine-based consultations prior to their surgery. There were comparable post-operative outcomes for patients evaluated entirely virtually preoperative compared to those evaluated with at least one traditional in-person evaluation. In both cohorts, 52% of patients followed up at one-year through our hernia surveillance program. The unanticipated recurrence rates observed were 0% for digital pre-operative patients, and 2.01% for patients evaluated in person pre-operatively (p = 1).
Conclusions: Based on the data presented here, virtual preoperative encounters are as safe and effective as traditional in-person evaluations for patients with small ventral hernias.
{"title":"Postoperative outcomes among patients evaluated via telemedicine-based preoperative consultations for small ventral hernias.","authors":"Shan L Kalmeta, Gustavo Salgado-Garza, Rebecca Prymak, Maggie E Bosley, Vahagn C Nikolian","doi":"10.1007/s10029-025-03564-9","DOIUrl":"https://doi.org/10.1007/s10029-025-03564-9","url":null,"abstract":"<p><strong>Purpose: </strong>During the COVID-19 pandemic, digital encounters became a crucial means of maintaining access to care amid restrictions on in-person interactions. As these limitations ease, it is essential to evaluate the outcomes of telehealth-based consultations. Before the pandemic, telehealth was predominantly used in postoperative care for surgical populations. This study examines the safety and efficacy of telehealth-based consultations compared to traditional in-person preoperative evaluations for small ventral hernia repair, contributing to the understanding of how telemedicine can be effectively integrated into surgical practices.</p><p><strong>Methods: </strong>We utilized a prospectively maintained single-center database from a tertiary referral hospital with a specialized hernia and abdominal wall reconstruction team to compare preoperative, intraoperative, and postoperative variables between ventral hernia patients who received telehealth-based (phone or video) consultations and those who had any in-person clinic evaluation.</p><p><strong>Results: </strong>A total of 187 patients with small (< 4 cm) ventral hernias were evaluated, with 42 (22%) being evaluated entirely through telemedicine-based consultations prior to their surgery. There were comparable post-operative outcomes for patients evaluated entirely virtually preoperative compared to those evaluated with at least one traditional in-person evaluation. In both cohorts, 52% of patients followed up at one-year through our hernia surveillance program. The unanticipated recurrence rates observed were 0% for digital pre-operative patients, and 2.01% for patients evaluated in person pre-operatively (p = 1).</p><p><strong>Conclusions: </strong>Based on the data presented here, virtual preoperative encounters are as safe and effective as traditional in-person evaluations for patients with small ventral hernias.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"65"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Incisional hernia (IH) is a significant complication that occurs after midline laparotomy and is associated with high morbidity and economic impacts. A fundamental goal of preventing IH is to determine which patients are considered low- or high-risk, as modifications in prevention techniques have been justified in high-risk patients.
Aim: of this study was to externally validate the IHXGBoost-P model to assess its accuracy, generalizability, and clinical applicability in an independent cohort.
Methods: A prospective cohort study was conducted in a tertiary hospital in Mexico (March 2021-December 2022) to externally validate the IHXGBoost-P model. Patients older than 18 years who underwent midline laparotomy and have a minimum follow-up of 24 months were included. The performance of the model was evaluated via area under the receiver operating characteristic curve (AUROC), accuracy, sensitivity, precision, specificity and calibration metrics.
Results: Of the 438 patients analyzed, 62 (14.1%) developed IH. The model demonstrated good discriminative capacity (Accuracy: 0.94 ± 0.015) and calibration (Brier score: 0.051). Key predictors included the risk of surgical site infection (odds ratio (OR): 3.01, 95% CI: 2.32-3.91), previous surgery, and body mass index (BMI). The specificity (0.97 ± 0.013) was determined to be high and useful for identifying lowrisk patients.
Conclusions: The IHXGBoost-P model is a reliable tool for predicting the risk of IH, with robust performance being observed in external validation. Its integration into clinical practice through a web application could optimize surgical decision-making to prevent IH.
{"title":"External validation of the IHXGboost-P model to predict incisional hernia after midline laparotomy.","authors":"Edgard Efren Lozada Hernandez, Tania A Ramirez-Delreal, Dagoberto Armenta-Medina, Sebastián Salazar-Colores","doi":"10.1007/s10029-025-03579-2","DOIUrl":"https://doi.org/10.1007/s10029-025-03579-2","url":null,"abstract":"<p><strong>Background: </strong>Incisional hernia (IH) is a significant complication that occurs after midline laparotomy and is associated with high morbidity and economic impacts. A fundamental goal of preventing IH is to determine which patients are considered low- or high-risk, as modifications in prevention techniques have been justified in high-risk patients.</p><p><strong>Aim: </strong>of this study was to externally validate the IHXGBoost-P model to assess its accuracy, generalizability, and clinical applicability in an independent cohort.</p><p><strong>Methods: </strong>A prospective cohort study was conducted in a tertiary hospital in Mexico (March 2021-December 2022) to externally validate the IHXGBoost-P model. Patients older than 18 years who underwent midline laparotomy and have a minimum follow-up of 24 months were included. The performance of the model was evaluated via area under the receiver operating characteristic curve (AUROC), accuracy, sensitivity, precision, specificity and calibration metrics.</p><p><strong>Results: </strong>Of the 438 patients analyzed, 62 (14.1%) developed IH. The model demonstrated good discriminative capacity (Accuracy: 0.94 ± 0.015) and calibration (Brier score: 0.051). Key predictors included the risk of surgical site infection (odds ratio (OR): 3.01, 95% CI: 2.32-3.91), previous surgery, and body mass index (BMI). The specificity (0.97 ± 0.013) was determined to be high and useful for identifying lowrisk patients.</p><p><strong>Conclusions: </strong>The IHXGBoost-P model is a reliable tool for predicting the risk of IH, with robust performance being observed in external validation. Its integration into clinical practice through a web application could optimize surgical decision-making to prevent IH.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"63"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1007/s10029-025-03568-5
Joshua Bruinsma, Niamh Moynagh, Benjamin M Mac Curtain, Nicholas A Clausen, Wanyang Qian, Mohammad Elfaki, Avinash Deshwal, Rostyslav Nikolenko, Ibrahim Haidaran, Hugo C Temperley, Zi Qin Ng
Purpose: Inguinal hernias are commonly encountered during robotic-assisted radical prostatectomy (RARP), either preoperatively or intraoperatively. Performing concurrent inguinal hernia repair (IHR) at the time of RARP may prevent the morbidity, cost, and inconvenience associated with a second operation. This systematic review and meta-analysis aimed to evaluate the safety and efficacy of concurrent IHR during RARP compared with RARP alone.
Methods: This study followed PRISMA guidelines and was prospectively registered with PROSPERO (CRD42025646245). Comprehensive searches of PubMed, EMBASE, and Cochrane CENTRAL were conducted to identify studies comparing outcomes of RARP with and without concurrent IHR. Primary outcomes included operative time, length of hospital stay, blood loss, and postoperative complications. A proportional meta-analysis was performed using a random-effects model, and heterogeneity was assessed using the I² statistic.
Results: Twenty studies comprising 1,402 patients who underwent concurrent IHR and 20,405 patients who underwent RARP alone were included. Concurrent IHR was associated with a statistically significant increase in operative time (mean difference 30.45 min; 95% CI 13.71-77.38) but showed no significant differences in postoperative complications, blood loss, or hospital stay. The pooled hernia recurrence rate was low (mean 1.9%), and Clavien-Dindo I-III complication rates were comparable between groups.
Conclusion: Concurrent IHR during RARP may be feasible, with perioperative outcomes broadly comparable to RARP alone. Concurrent repair may be considered in selected patients and experienced centres however given study heterogeneity and the predominance of retrospective evidence, these findings should be interpreted cautiously.
Trial registration: The trial was prospectively registered on PROSPERO on 03/02/2025 under ID: CRD42025646245.
目的:腹股沟疝是机器人辅助根治性前列腺切除术(RARP)中常见的并发症,无论是术前还是术中。在RARP时进行并发腹股沟疝修补术(IHR)可以避免与第二次手术相关的发病率、成本和不便。本系统综述和荟萃分析旨在评价RARP期间并发IHR与单独RARP期间的安全性和有效性。方法:本研究遵循PRISMA指南,并在PROSPERO (CRD42025646245)进行前瞻性注册。对PubMed、EMBASE和Cochrane CENTRAL进行综合检索,以确定比较RARP合并和不合并IHR的结果的研究。主要结局包括手术时间、住院时间、出血量和术后并发症。采用随机效应模型进行比例荟萃分析,采用I²统计量评估异质性。结果:纳入了20项研究,包括1402例同时进行IHR的患者和20405例单独进行RARP的患者。并发IHR与手术时间增加有统计学意义(平均差异30.45分钟;95% CI 13.71-77.38),但在术后并发症、失血或住院时间方面无显著差异。合并疝复发率较低(平均1.9%),Clavien-Dindo I-III并发症发生率组间比较。结论:RARP期间并发IHR可能是可行的,其围手术期结果与单独RARP大致相当。在选定的患者和有经验的中心可以考虑同时修复,但是考虑到研究的异质性和回顾性证据的优势,这些发现应该谨慎解释。试验注册:该试验于2025年2月3日在PROSPERO前瞻性注册,ID: CRD42025646245。
{"title":"Concurrent inguinal hernia repair during robotic radical prostatectomy: a systematic review and meta-analysis.","authors":"Joshua Bruinsma, Niamh Moynagh, Benjamin M Mac Curtain, Nicholas A Clausen, Wanyang Qian, Mohammad Elfaki, Avinash Deshwal, Rostyslav Nikolenko, Ibrahim Haidaran, Hugo C Temperley, Zi Qin Ng","doi":"10.1007/s10029-025-03568-5","DOIUrl":"10.1007/s10029-025-03568-5","url":null,"abstract":"<p><strong>Purpose: </strong>Inguinal hernias are commonly encountered during robotic-assisted radical prostatectomy (RARP), either preoperatively or intraoperatively. Performing concurrent inguinal hernia repair (IHR) at the time of RARP may prevent the morbidity, cost, and inconvenience associated with a second operation. This systematic review and meta-analysis aimed to evaluate the safety and efficacy of concurrent IHR during RARP compared with RARP alone.</p><p><strong>Methods: </strong>This study followed PRISMA guidelines and was prospectively registered with PROSPERO (CRD42025646245). Comprehensive searches of PubMed, EMBASE, and Cochrane CENTRAL were conducted to identify studies comparing outcomes of RARP with and without concurrent IHR. Primary outcomes included operative time, length of hospital stay, blood loss, and postoperative complications. A proportional meta-analysis was performed using a random-effects model, and heterogeneity was assessed using the I² statistic.</p><p><strong>Results: </strong>Twenty studies comprising 1,402 patients who underwent concurrent IHR and 20,405 patients who underwent RARP alone were included. Concurrent IHR was associated with a statistically significant increase in operative time (mean difference 30.45 min; 95% CI 13.71-77.38) but showed no significant differences in postoperative complications, blood loss, or hospital stay. The pooled hernia recurrence rate was low (mean 1.9%), and Clavien-Dindo I-III complication rates were comparable between groups.</p><p><strong>Conclusion: </strong>Concurrent IHR during RARP may be feasible, with perioperative outcomes broadly comparable to RARP alone. Concurrent repair may be considered in selected patients and experienced centres however given study heterogeneity and the predominance of retrospective evidence, these findings should be interpreted cautiously.</p><p><strong>Trial registration: </strong>The trial was prospectively registered on PROSPERO on 03/02/2025 under ID: CRD42025646245.</p>","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"64"},"PeriodicalIF":2.4,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145989048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sutureless versus conventional open herniotomy in children with unilateral inguinal hernia.","authors":"Raashid Hamid, Akshat Sudhanshu, Vivek Sharma, Nisar A Bhat, Sabina Nisar","doi":"10.1007/s10029-025-03538-x","DOIUrl":"https://doi.org/10.1007/s10029-025-03538-x","url":null,"abstract":"","PeriodicalId":13168,"journal":{"name":"Hernia","volume":"30 1","pages":"60"},"PeriodicalIF":2.4,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}