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"My Health, My Right:" There Is More to It than Meets the Eye. "我的健康,我的权利:"其意义远不止于此。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_478_24
Rajib Dasgupta, Rama Baru

The WHO's World Health Day 2024 slogan, "My health, my right," has been unpacked through the lens of an evolving social epidemiological understanding. The operative part of the theme merely reiterates international positions that have been established for a long and is unable to adequately incorporate advances in the understanding of the central role that structural determinants play in the production of ill-health. Given the urgency of addressing Sustainable Development Goal and Universal Health Coverage goals, the reduction of health inequities through the promotion of social justice is as much a governance imperative as moral.

世卫组织 2024 年世界卫生日的口号 "我的健康,我的权利 "是通过不断发展的社 会流行病学认识来解读的。该主题的执行部分只是重申了长期以来确立的国际立场,未能充分纳入对结构性决定因素在造成不健康方面所起核心作用的认识的进展。鉴于实现可持续发展目标和全民医保目标的紧迫性,通过促进社会公正来减少卫 生不公平现象既是治理的需要,也是道德的需要。
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引用次数: 0
"The Early Years are Like a Foundation for the Future" Perspectives, Facilitators, and Challenges of Anganwadi Workers in Supporting Early Child Development Interventions in Hyderabad, India: Qualitative Findings from a Scalable Program Incorporating Early Child Development Interventions. "幼年是未来的基础",印度海得拉巴 Anganwadi 工作者在支持儿童早期发展干预措施方面的观点、促进因素和挑战:一项纳入儿童早期发展干预措施的可扩展计划的定性研究结果。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_868_23
Gitanjali Lall, Reetabrata Roy, Kunduru Sharath Chandrika, Gauri Divan

Background: Integrated Child Development Services (ICDS) scheme, a large public health program, addresses the needs of young children with Anganwadi Workers (AWWs) as frontline agents of delivery. A scalable program incorporating early child development interventions (ASPIRE) has been developed to complement the program and address some of its gaps.

Objectives: This paper describes formative work done with AWWs, as part of ASPIRE to assess their understanding of early childhood development (ECD) and acceptability of a novel ECD intervention using digital technology.

Materials and methods: Six focus group discussions (FGDs) were conducted with 31 AWWs, using a semi-structured guide.

Results: Framework analysis of their responses from FGDs led to the identification of three themes: (1) time use, (2) understanding of ECD, and (3) delivering messages using videos. The findings suggest that AWWs tight schedules often leave them feeling overburdened with work. They are aware of factors that can aid as well as hinder child growth and development, but their understanding of play is limited to games played by older children. They expressed acceptability in using a video intervention, specifying features that would increase relevance for families.

Conclusion: Integration of novel ECD interventions delivered by frontline workers needs to take into account their existing work schedules and associated challenges. Training on ECD interventions will need to broaden AWWs understanding of the critical foundational experiences which responsive caregiving and early child stimulation can provide.

背景:儿童综合发展服务计划(ICDS)是一项大型的公共卫生计划,由 Anganwadi 工作者(AWW)作为第一线的服务提供者来满足幼儿的需求。为了补充该计划并弥补其中的一些不足,我们制定了一项包含儿童早期发展干预措施的可扩展计划(ASPIRE):本文介绍了作为 ASPIRE 计划的一部分,与儿童福利工作者共同开展的形成性工作,以评估他们对儿童早期发展(ECD)的理解以及对使用数字技术的新型儿童早期发展干预措施的接受程度:采用半结构化指南,与 31 名儿童福利工作者进行了六次焦点小组讨论(FGD):对他们在焦点小组讨论中的回答进行框架分析后,确定了三个主题:(1) 时间利用,(2) 对幼儿发展的理解,(3) 利用视频传递信息。研究结果表明,工作时间紧张常常使儿童福利工作者感到工作负担过重。她们知道有哪些因素既能帮助也能阻碍儿童的成长和发展,但她们对游戏的理解仅限于大孩子玩的游戏。他们表示可以接受使用视频干预,并具体说明了可提高家庭相关性的特点:结论:整合由一线工作者提供的新型幼儿发展干预措施需要考虑到他们现有的工作安排和相关挑战。幼儿发展干预措施的培训需要拓宽一线工作者对回应性照料和早期儿童刺激所能提供的重要基础经验的理解。
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引用次数: 0
Neonatal Mortality and Associated Factors in Tribal Community. 部落社区新生儿死亡率及相关因素。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_1494_23
Dinesh Kumar, Suyesh Srivastava
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引用次数: 0
Public Health System's Preparedness to Address Polycystic Ovarian Syndrome: A Rapid Assessment Survey of Health-care Providers in India. 公共卫生系统应对多囊卵巢综合征的准备情况:印度医疗保健提供者快速评估调查》。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_15_23
Beena Nitin Joshi, Sharmeen Akhtar Shaikh, Amlin Shukla, Mohd Ashraf Ganie, Imtiyaz Ahmad Wani, Vanita Suri, Neena Malhotra, Sarita Agarwal, Subhankar Chowdhury, Prasanta Kumar Bhattacharya, Rakesh Kumar Sahay, Roya Rozati, Puthiyaveettil Khadar Jabbar, Abilash Nair, Bharti Kulkarni, Aafia Rashid, Sunny Khajuria, Monica Rajput, Gaivee Vinam Meshram, Shouvik Chowdhury, Rahul Harish Bamon, Muhammed Shahid Pasha, Farhana Begum, Manoj Rema Aravind, Taruna Arora

Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders largely affecting women of reproductive age group.

Objectives: This study aimed to understand the Indian public health-care systems' preparedness in addressing PCOS.

Materials and methods: A multicentric rapid assessment cross-sectional study was undertaken among 173 health-care providers serving across various public health-care facilities in India. This study was a component of a larger task force study that aimed to estimate the community-based prevalence of PCOS in India. Information on PCOS cases reported that knowledge about PCOS diagnosis, management practices, availability of diagnostic facilities, and drugs was explored.

Results: Irregular menstrual cycle was the most commonly reported PCOS symptom. Most of the health-care providers (HCPs) lacked correct knowledge about diagnostic criteria and investigation needed for the diagnosis of PCOS. Diagnostic facilities and drugs were inadequate. However, some facilities had access to investigations through public-private partnerships. Awareness programs on PCOS in the community were negligible, and PCOS cases were not documented. Training HCPs on PCOS along with the availability of specialists and strengthening diagnostic facilities were some major demands from the HCPs.

Conclusion: Results suggest the need for training HCPs, strengthening infrastructure with good referral linkages, and adequate supply of drugs to help improve PCOS management at public health-care facilities in India. There is a need to develop national technical and operational guidelines to address PCOS using a multidisciplinary approach across all levels of care. Creating demand for services and advocating healthy lifestyles through community awareness can help early diagnosis and prevention of complications.

背景:多囊卵巢综合征(PCOS多囊卵巢综合征(PCOS)是最常见的内分泌疾病之一,主要影响育龄妇女:本研究旨在了解印度公共医疗系统在应对多囊卵巢综合征方面的准备情况:这项多中心快速评估横断面研究的对象是印度各种公共医疗机构的 173 名医疗服务提供者。该研究是一项大型特别工作组研究的组成部分,旨在估算印度多囊卵巢综合症的社区患病率。对多囊卵巢综合症病例的信息报告、多囊卵巢综合症的诊断知识、管理方法、诊断设施的可用性以及药物进行了探讨:结果:月经周期不规律是最常报告的多囊卵巢综合症症状。大多数医疗服务提供者(HCPs)对多囊卵巢综合征的诊断标准和诊断所需的检查缺乏正确的认识。诊断设施和药物不足。不过,一些医疗机构通过公私合作的方式获得了检查手段。社区对多囊卵巢综合症的宣传计划微不足道,多囊卵巢综合症病例也没有记录在案。对保健专业人员进行有关多囊卵巢综合症的培训、提供专家和加强诊断设施是保健专业人员提出的一些主要要求:结论:研究结果表明,有必要对初级保健人员进行培训,加强具有良好转诊联系的基础设施,并提供充足的药物,以帮助改善印度公共医疗机构对多囊卵巢综合症的管理。有必要制定国家技术和操作指南,在各级医疗机构采用多学科方法治疗多囊卵巢综合症。通过社区宣传来创造对服务的需求和倡导健康的生活方式,有助于早期诊断和预防并发症。
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引用次数: 0
Roles, Responsibilities, and Functions of Village Health, Sanitation, and Nutrition Committees in India: A Qualitative Evidence Synthesis. 印度乡村健康、卫生和营养委员会的作用、责任和职能:定性证据综述》。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_149_23
Sathish Rajaa, Senthilkumar Ramalingam, Maulik Chokashi, Tushar Mokashi

National Health Mission instituted the Village Health, Sanitation, and Nutrition Committees (VHSNCs) in 2005, with an aim of ensuring health and well-being for local communities in India. There is a lack of concrete evidence on the functioning of VHSNCs at a national level. Thus, this study was undertaken to outline the roles, responsibilities, and functions of VHSNCs in India. We conducted a comprehensive data search in Medline, Cochrane Library, ScienceDirect, EMBASE, and Google Scholar between 2005 and August 2021. All peer-reviewed qualitative studies that reported the roles, responsibilities, functions, and good practices of VHSNCs from India were included in our review. Critical Appraisal Skills Programme checklist was used to assess the quality of individual studies. In total, we included 15 studies (including 1100+ VHSNCs) from various states of India. Our review highlighted that the majority of the VHSNCs functioned without a clear-cut definition of roles and responsibilities had irregular meetings and workforce shortage. There was a lack of inclusivity, accountability, and delay in the processing of untied funds. The included studies have showed that VHSNCs were involved health promotional activities such as formulation and implementation of village health plans, delivery of services through public distribution systems, ensuring safe drinking water and sanitary supervision, and identification and referral of malnourished children. Our review highlights the crucial role that VHSNCs play in improving the health outcomes of rural populations and underscores the need for continued support and capacity-building efforts to ensure their effectiveness.

国家卫生使命于 2005 年设立了乡村健康、卫生和营养委员会(VHSNCs),旨在确保印度当地社区的健康和福祉。目前还缺乏有关村保健、卫生和营养委员会在全国范围内运作情况的具体证据。因此,我们开展了这项研究,以概述印度村卫生服务网络的作用、责任和职能。我们在 Medline、Cochrane 图书馆、ScienceDirect、EMBASE 和 Google Scholar 中进行了一次全面的数据搜索,时间跨度为 2005 年至 2021 年 8 月。所有经过同行评议、报告了印度自愿失踪儿童家庭的角色、责任、功能和良好实践的定性研究都被纳入了我们的综述。我们使用 "批判性评估技能计划 "清单来评估各项研究的质量。我们总共收录了来自印度各邦的 15 项研究(包括 1100 多家自愿失踪儿童家庭服务机构)。我们的审查结果表明,大多数自愿医疗服务全国委员会在运作过程中没有明确的角色和职责定义,会议不定期举行,劳动力短缺。在处理不附带条件的资金方面,缺乏包容性、问责制和延迟性。所纳入的研究表明,村卫生服务全国委员会参与了卫生宣传活动,如制定和实施村卫生计划,通过公共分配系统提供服务,确保安全饮用水和卫生监督,以及营养不良儿童的识别和转诊。我们的审查强调了村卫生服务全国委员会在改善农村人口健康状况方面发挥的关键作用,并强调有必要继续提供支持和开展能力建设工作,以确保其有效性。
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引用次数: 0
Air Quality and Public Health Risk Assessment: A Case of an Industrial Area in Haridwar City, Uttarakhand (India). 空气质量与公共健康风险评估:印度北阿坎德邦哈里瓦市工业区案例。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_279_23
Alka Pant, Ramesh Chandra Joshi, Sanjay Sharma, Kamal Pant

Background: Air pollution is a significant issue for a developing country like India and the air quality index (AQI) forecasting helps to predict air quality levels in advance and allows individuals to take precautionary measures to protect their health.

Objectives: The study aimed to forecast the AQI for an industrial area (SIDCUL, Haridwar City) using a time series regression model.

Materials and methods: Three years of existing AQI data points (post-COVID-19) were collected from the Uttarakhand Pollution Control Board for the SIDCUL area of Haridwar City and tried to know the status of AQI values for the following 12 months. Trend and seasonality components were seen through the decomposition process. Further, the augmented Dickey-Fuller test was applied to check the stationarity of the series before finalizing the best-suited time series model for forecasting the AQI values.

Results: With the help of autocorrelation function (ACF)/partial ACF plots, a seasonal autoregressive integrated moving average (ARIMA) (0,1,0) (1,0,0)[12] model was selected with the minimum akaike information criterion (253.143) and mean absolute percentage error (17.42%). The AQI values have also been forecasted for this industrial area (SIDCUL) for the following year.

Conclusion: The seasonal ARIMA (0,1,0) (1,0,0)[12] model may be helpful to forecast the AQI values for a nonstationary time series dataset. Research indicates that the air of the SIDCUL area will become moderately polluted and may cause breathing discomfort to asthma patients' health. The scientists might apply this model to other polluted regions of the country so that the public and the government can take preventive measures in advance.

背景:空气污染是印度这样的发展中国家面临的一个重要问题,空气质量指数(AQI)预测有助于提前预测空气质量水平,使个人能够采取预防措施保护健康:研究旨在利用时间序列回归模型预测一个工业区(哈里瓦市 SIDCUL)的空气质量指数:从北阿坎德邦污染控制委员会收集了哈里德瓦尔市 SIDCUL 地区现有的三年空气质量指数数据点(COVID-19 后),并试图了解随后 12 个月的空气质量指数值状况。通过分解过程可以看出趋势和季节性成分。此外,在最终确定最适合预测空气质量指数值的时间序列模型之前,还应用了增强型 Dickey-Fuller 检验来检查序列的静态性:在自相关函数(ACF)/部分 ACF 图的帮助下,选择了一个季节性自回归综合移动平均(ARIMA)(0,1,0)(1,0,0)[12] 模型,该模型的阿凯克信息准则(253.143)和平均绝对百分比误差(17.42%)最小。同时还预测了该工业区(SIDCUL)下一年的空气质量指数值:结论:季节性 ARIMA (0,1,0) (1,0,0)[12] 模型可能有助于预测非平稳时间序列数据集的空气质量指数值。研究表明,SIDCUL 地区的空气将变得中度污染,可能会对哮喘患者的健康造成呼吸不适。科学家可将该模型应用于国内其他污染地区,以便公众和政府提前采取预防措施。
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引用次数: 0
How Did We Deal with the Pandemic? - Experience from a Tertiary Health Institute in Eastern India. 我们是如何应对大流行病的?- 印度东部一所三级医疗机构的经验。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_1444_22
Jawahar S K Pillai, Biswajeevan Sahoo, Thean Singh, Siddharth Mishra, Ramkrishna Mondal, Kiran Mv Kumar

With the introduction of the novel coronavirus in late 2019, the healthcare system of every country in the world experienced many challenges. In India, every healthcare organization has prepared itself to fight against these global challenges. This study aims to describe the challenges faced during the COVID-19 pandemic and how we dealt with the pandemic successfully. This narrative analysis study was made in a 960-bedded teaching hospital during the pandemic. The challenges were identified from the minutes of meetings, circulars issued, and various strategic decisions made to combat the pandemic. The challenges faced by the institute were categorized into nine different categories: infrastructural, human resource, hospital operations, and others. Lack of knowledge during the initial days of the pandemic, need for round-theclock situational management, and day-to-day operation needed aggressive training and adherence to the guidelines. Gaps identified in areas like inventory, infection control, logistics, etc., were quickly addressed, and processes were created as per the nation's changing guidelines. This study revealed strategies to manage the pandemic by optimally utilizing available resources with good teamwork and situational leadership.

随着 2019 年底新型冠状病毒的出现,世界各国的医疗保健系统都经历了许多挑战。在印度,每个医疗机构都做好了应对这些全球性挑战的准备。本研究旨在描述 COVID-19 大流行期间所面临的挑战,以及我们是如何成功应对此次大流行的。这项叙事分析研究是在一家拥有 960 张床位的教学医院进行的。我们从会议记录、发布的通知以及为应对大流行而做出的各种战略决策中发现了所面临的挑战。医院面临的挑战分为九个不同的类别:基础设施、人力资源、医院运营和其他。在大流行病初期缺乏知识、需要全天候的态势管理、日常运作需要积极的培训和对指导方针的遵守。在库存、感染控制、后勤等方面发现的差距得到了迅速解决,并根据国家不断变化的指导方针制定了流程。这项研究揭示了通过良好的团队合作和情境领导优化利用现有资源来管理大流行病的战略。
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引用次数: 0
Plagiarism and Authorship Credit. 剽窃与著作权。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_1071_23
Albina Arjuman, Somen N Chakraborty

Literature being an expression of an author, its commodification historically has assigned a value to it primarily in terms of authorship credit. Arguably reproducing published content without attributing the requisite source, termed as plagiarism is ethically discrediting to this premise. However, simply weighing its proportion based on digitally assigned semantic similarity may not be completely justifiable in the present-day digital atmosphere. It should be noted that while technology can facilitate plagiarism detection, digitization by way of providing greater access to published content is also the facilitator of plagiarism. While the scientific community is often severe in its approach toward the act of plagiarism, there is still a lack of clarity around the code of conduct of the same as there are several grey areas related to such a misconduct on which the law remains silent. By revisiting the historical evolution of the credit of authorship and the copyright law this piece presents an analytical vista pertaining to plagiarism in a different light. By identifying the gaps in the present-day handling of these age-old concepts, one may find that there is an unmet need to revisit the legal aspects of handling cases of plagiarism taking into consideration the digital environment.

文学作为作者的一种表达方式,其商品化的价值历来主要体现在作者署名方面。可以说,在不注明必要来源的情况下复制已发表的内容,即所谓的剽窃行为,在道德上是有悖于这一前提的。然而,在当今的数字环境中,简单地根据数字指定的语义相似性来权衡其比例可能并不完全合理。需要指出的是,技术固然有助于发现剽窃行为,但通过提供更多获取已发表内容的途径而实现的数字化也为剽窃行为提供了便利。虽然科学界对剽窃行为的态度往往是严厉的,但对剽窃行为的行为准则仍然缺乏明确的规定,因为与这种不当行为有关的一些灰色地带,法律仍然保持沉默。通过重新审视著作权和版权法的历史演变,这篇文章从另一个角度对抄袭行为进行了分析。通过找出当今处理这些古老概念的差距,人们可能会发现,考虑到数字环境,重新审视处理剽窃案件的法律方面的需求尚未得到满足。
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引用次数: 0
The Human Papillomavirus Enigma: A Narrative Review of Global Variations in Oropharyngeal Cancer Epidemiology and Prognosis. 人类乳头瘤病毒之谜:口咽癌流行病学和预后的全球差异综述》。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_827_23
Hitesh Rajendra Singhavi, Pankaj Chaturvedi, Deepa Nair

Oropharyngeal cancers (OPCs) in Asia account for 42% of the global burden and over 50% of related deaths. Human papillomavirus (HPV) is involved in over 70% of OPC cases in the Western hemisphere, but its role in the Eastern hemisphere is unclear. This study reviews OPC epidemiology, including prevalence, etiological factors (such as smokeless tobacco and HPV), and their interaction. Among the SEAR countries, India had the highest incidence of HPV-related OPCs at 38.4%, while data were unavailable for most African countries, with only a 14% incidence reported. Conversely, the American region exhibited one of the highest HPV positivity rates, reaching up to 65% in different states of the USA, while Brazil reported an incidence of up to 38%. In the European Union, the UK had the highest incidence of HPV-associated OPC, reaching up to 52%. In the Western Pacific region, New Zealand demonstrated the highest incidence at up to 78%. Smokeless tobacco consumption was higher in SEAR countries, which had a relatively lower incidence of HPV infection, suggesting a negative correlation between the two. Based on our literature search, the most common detection methods used globally are immunohistochemistry for p16 and polymerized chain reaction. OPCs are a global health concern, and proper identification and classification are vital. HPV-driven cancers have better survival rates, emphasizing the need for focused research on specific problem areas based on the burden of HPV-positive or HPV-negative cancers.

亚洲的口咽癌(OPCs)发病率占全球发病率的 42%,相关死亡人数超过 50%。在西半球,70%以上的口咽癌病例与人类乳头瘤病毒(HPV)有关,但其在东半球的作用尚不清楚。本研究回顾了 OPC 流行病学,包括发病率、致病因素(如无烟烟草和 HPV)及其相互作用。在东南亚地区国家中,印度与 HPV 相关的 OPC 发病率最高,为 38.4%,而大多数非洲国家没有相关数据,报告的发病率仅为 14%。相反,美洲地区是 HPV 阳性率最高的地区之一,在美国各州高达 65%,而巴西报告的发病率高达 38%。在欧盟,英国的 HPV 相关 OPC 发病率最高,达到 52%。在西太平洋地区,新西兰的发病率最高,高达78%。东南亚地区国家的无烟烟草消费量较高,而这些国家的HPV感染率相对较低,这表明两者之间存在负相关。根据我们的文献检索,全球最常用的检测方法是 p16 免疫组化和聚合链反应。卵巢癌是全球关注的健康问题,正确的鉴别和分类至关重要。HPV驱动的癌症存活率更高,因此需要根据HPV阳性或HPV阴性癌症的负担情况,对特定问题领域进行重点研究。
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引用次数: 0
Does Price Really Matter for Generic Alternatives? Supervised learning Approaches in Deciding the Right Price for Acceptable Quality Attributes of Amlodipine Besylate among Generic Alternatives. 仿制药替代品的价格真的重要吗?在非专利替代品中决定可接受质量属性的苯磺酸氨氯地平合适价格的监督学习方法。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI: 10.4103/ijph.ijph_345_23
Laltanpuii Chenkual, Mahindran Mariyappan, Dimple S Lalchandani, Khajapeer Shaikh, Pavan Kumar Sathala, Pawan Kumar Porwal

The price and safety of finished pharmaceutical preparations are two major concerns while prescribing medicine. In this work, machine learning-based classification models were developed with respect to the quality attributes of 258 samples covering 9 marketed amlodipine (AMLO) formulations. The quantitation of AMLO and its three sulfonate ester genotoxic impurities of besylate counter ion was settled using a validated high-performance liquid chromatography-diode-array detection method. The classification of correlation between dependent and independent variables was exercised using linear discriminant analysis models. The linear dispersion of acceptable quality attributes was significantly different for AMLO besylate formulation with unit price per tablet "<1 Rs." Although the correlations between price and quality are well-understood associations group centroid distance for price group "2-3 Rs." and "1-2 Rs." reveal that acceptable quality dispersion was similar for both groups. Nonetheless, a higher price could allow storage of the finished formulation to be kept on the shelf for a longer period.

成品药物制剂的价格和安全性是处方药的两大关注点。在这项工作中,针对 258 个样品的质量属性开发了基于机器学习的分类模型,这些样品涵盖了 9 种已上市的氨氯地平(AMLO)制剂。使用经过验证的高效液相色谱-二极管阵列检测方法,对苯磺酸反离子的 AMLO 及其三种磺酸酯类基因毒性杂质进行了定量。使用线性判别分析模型对因变量和自变量之间的相关性进行了分类。结果表明,AMLO 苯磺酸盐制剂的合格质量属性的线性分散性与每片单价"
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引用次数: 0
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Indian journal of public health
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