Pub Date : 2023-05-01DOI: 10.4103/kleuhsj.kleuhsj_567_22
Vinaya A. Singh, M. Khan, S. Malik, Poonam Wade, V. Kulkarni
Neonatal thrombocytopenia is a common entity encountered in neonatal intensive care unit. Diagnosis often becomes challenging because of broad range of possible clinical diagnoses. Careful evaluation and history taking are the backbone of sound diagnosis. During such diagnostic dilemma, investigation as basic as peripheral smear examination can come to a rescue. Here, we present a rare case of neonatal autoimmune thrombocytopenia. On the basis of detailed history, careful examination, and basic investigations, diagnosis of May–Hegglin anomaly was made which was later confirmed by genetic studies (rare mutation in myosin heavy chain 9 gene).
{"title":"May–Hegglin anomaly: A rare hereditary autoimmune thrombocytopenia","authors":"Vinaya A. Singh, M. Khan, S. Malik, Poonam Wade, V. Kulkarni","doi":"10.4103/kleuhsj.kleuhsj_567_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_567_22","url":null,"abstract":"Neonatal thrombocytopenia is a common entity encountered in neonatal intensive care unit. Diagnosis often becomes challenging because of broad range of possible clinical diagnoses. Careful evaluation and history taking are the backbone of sound diagnosis. During such diagnostic dilemma, investigation as basic as peripheral smear examination can come to a rescue. Here, we present a rare case of neonatal autoimmune thrombocytopenia. On the basis of detailed history, careful examination, and basic investigations, diagnosis of May–Hegglin anomaly was made which was later confirmed by genetic studies (rare mutation in myosin heavy chain 9 gene).","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"26 1","pages":"316 - 319"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77905642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.4103/kleuhsj.kleuhsj_101_22
R. Nerli, Keyur Patel, S. Rai, S. Rangrez, Neeraj S. Dixit
INTRODUCTION: The complications of benign prostatic hyperplasia (BPH) among others include bladder stones. The prevalence of vesical calculus is eight times higher in men having BPH (3.4%) as compared with men without BPH (0.4%). The guidelines suggest that BPH obstruction should be managed along with removal of bladder stones. The objective of the study was to study the outcome of surgery in patients with BPH and bladder calculi. MATERIALS AND METHODS: This prospective study included all patients undergoing surgical treatment for BPH with vesical calculi. Outcomes were measured in terms of blood loss, operating time, days of hospitalization, postoperative urinary flow, postvoid residual, and complications. RESULTS: Five (13.51%) patients underwent perurethral cystolitholapaxy, 17 (45.94%) underwent percutaneous suprapubic cystolitholapaxy, and the remaining 15 (40.54%) underwent open cystolithotomy for bladder stones. The prostate (BPH) was managed by monopolar transurethral resection of prostate (TURP) in 14 (37.83%), bipolar TURP in 12 (32.43%), and laser prostatectomy (Holmium enucleation) in the remaining 11 (29.72%). At the time of discharge, all patients were free of bladder stones and voided well. At 3-month follow-up, the mean Q-max was 18.65 mL/s. CONCLUSIONS: Simultaneous management of BPH and bladder stones is safe and effective. The procedure chosen for managing bladder stones depends on the size, number, and experience of the surgeon. Smaller stones can be easily managed by minimally invasive procedures such as perurethral cystolitholapaxy and percutaneous cystolitholapaxy.
{"title":"Outcome of management of patients with BPH and vesical calculi","authors":"R. Nerli, Keyur Patel, S. Rai, S. Rangrez, Neeraj S. Dixit","doi":"10.4103/kleuhsj.kleuhsj_101_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_101_22","url":null,"abstract":"INTRODUCTION: The complications of benign prostatic hyperplasia (BPH) among others include bladder stones. The prevalence of vesical calculus is eight times higher in men having BPH (3.4%) as compared with men without BPH (0.4%). The guidelines suggest that BPH obstruction should be managed along with removal of bladder stones. The objective of the study was to study the outcome of surgery in patients with BPH and bladder calculi. MATERIALS AND METHODS: This prospective study included all patients undergoing surgical treatment for BPH with vesical calculi. Outcomes were measured in terms of blood loss, operating time, days of hospitalization, postoperative urinary flow, postvoid residual, and complications. RESULTS: Five (13.51%) patients underwent perurethral cystolitholapaxy, 17 (45.94%) underwent percutaneous suprapubic cystolitholapaxy, and the remaining 15 (40.54%) underwent open cystolithotomy for bladder stones. The prostate (BPH) was managed by monopolar transurethral resection of prostate (TURP) in 14 (37.83%), bipolar TURP in 12 (32.43%), and laser prostatectomy (Holmium enucleation) in the remaining 11 (29.72%). At the time of discharge, all patients were free of bladder stones and voided well. At 3-month follow-up, the mean Q-max was 18.65 mL/s. CONCLUSIONS: Simultaneous management of BPH and bladder stones is safe and effective. The procedure chosen for managing bladder stones depends on the size, number, and experience of the surgeon. Smaller stones can be easily managed by minimally invasive procedures such as perurethral cystolitholapaxy and percutaneous cystolitholapaxy.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"452 1","pages":"210 - 214"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77519485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.4103/kleuhsj.kleuhsj_493_22
Uma Kole, Sudha A. Raddi, A. Dalal
INTRODUCTION: Goal 3 of sustainable development aims to ensure healthy lives and promote well-being for all people of all ages. One of the components for achieving this objective is the improvement of maternal and child health, with the perinatal mortality (PM) rate serving as an indicator. This study aimed to know the probable cause of perinatal death at a medical center of tertiary care to reduce the incidence of perinatal death and enhance the quality of care. OBJECTIVE: The objective of this study was to study the incidence and associated risk factors of PM in a selected tertiary care hospital. MATERIALS AND METHODS: A prospective case series study was conducted from August 2019 to September 2021 among all pregnant mothers who delivered in selected tertiary care hospitals of Belagavi city among 3508 participants. RESULTS: In the present study, results revealed that 29 per 1000 births and 7.12 per 1000 live births of END. The incidence of PM was 36.48 per 1000 births in the present study. There was a positive correlation between maternal weight in kg versus the birth weight of the baby (R = 0.091, P < 0.001). Results inferred that maternal anemia, antepartum hemorrhage, hypertensive disorders, thyroid disorders, amniotic fluid infections, and placental insufficiency were identified as primary causes of stillbirth. CONCLUSION: There is a region-wise wide variation in the rate of PM. There was an inverse relationship between birth weight and stillbirth, neonatal death, and perinatal death rate. Low birth weight babies contributed more than three times to stillbirths, early neonatal deaths, and perinatal deaths as compared to babies with normal birth weight.
导言:可持续发展目标3旨在确保健康的生活方式，促进各年龄段所有人的福祉。实现这一目标的组成部分之一是改善孕产妇和儿童健康，围产期死亡率是一项指标。本研究旨在了解三级医疗中心围产期死亡的可能原因，以降低围产期死亡发生率，提高护理质量。目的:本研究的目的是研究在选定的三级保健医院PM的发病率和相关危险因素。材料与方法:2019年8月至2021年9月，在贝拉加维市选定的三级医院分娩的所有孕妇中，对3508名参与者进行了前瞻性病例系列研究。结果:在本研究中，结果显示，每1000个新生儿中有29个，每1000个活产婴儿中有7.12个。在本研究中，PM的发病率为36.48 / 1000。产妇体重(kg)与婴儿出生体重呈正相关(R = 0.091, P < 0.001)。结果表明，产妇贫血、产前出血、高血压疾病、甲状腺疾病、羊水感染和胎盘功能不全是导致死产的主要原因。结论:不同地区PM率存在较大差异。出生体重与死产、新生儿死亡和围产期死亡率呈负相关。与正常出生体重的婴儿相比，低出生体重婴儿对死产、新生儿早期死亡和围产期死亡的贡献是正常出生体重婴儿的三倍多。
{"title":"Maternal and neonatal determinants of perinatal mortality in selected tertiary care hospital of North Karnataka","authors":"Uma Kole, Sudha A. Raddi, A. Dalal","doi":"10.4103/kleuhsj.kleuhsj_493_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_493_22","url":null,"abstract":"INTRODUCTION: Goal 3 of sustainable development aims to ensure healthy lives and promote well-being for all people of all ages. One of the components for achieving this objective is the improvement of maternal and child health, with the perinatal mortality (PM) rate serving as an indicator. This study aimed to know the probable cause of perinatal death at a medical center of tertiary care to reduce the incidence of perinatal death and enhance the quality of care. OBJECTIVE: The objective of this study was to study the incidence and associated risk factors of PM in a selected tertiary care hospital. MATERIALS AND METHODS: A prospective case series study was conducted from August 2019 to September 2021 among all pregnant mothers who delivered in selected tertiary care hospitals of Belagavi city among 3508 participants. RESULTS: In the present study, results revealed that 29 per 1000 births and 7.12 per 1000 live births of END. The incidence of PM was 36.48 per 1000 births in the present study. There was a positive correlation between maternal weight in kg versus the birth weight of the baby (R = 0.091, P < 0.001). Results inferred that maternal anemia, antepartum hemorrhage, hypertensive disorders, thyroid disorders, amniotic fluid infections, and placental insufficiency were identified as primary causes of stillbirth. CONCLUSION: There is a region-wise wide variation in the rate of PM. There was an inverse relationship between birth weight and stillbirth, neonatal death, and perinatal death rate. Low birth weight babies contributed more than three times to stillbirths, early neonatal deaths, and perinatal deaths as compared to babies with normal birth weight.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"5 1","pages":"264 - 267"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90082487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_580_22
D. Keerthana, P. Angadi
Fibrolipoma is a benign neoplasm categorized as a histopathological variant of classical lipoma. The occurrence of fibrolipoma in the oral cavity is extremely rare. When present, it manifests as a pedunculated or sessile, soft, smooth-surfaced nodular mass. Although it may vary, the majority of lesions are <5 cm in size. There may be association between functional and aesthetic limitations related to anatomical sites. Hence, it is crucial to properly examine lipomas histopathologically for better treatment modalities. Here is a case report of fibrolipoma occurring in buccal mucosa.
{"title":"Fibrolipoma of the buccal mucosa: A rare case report","authors":"D. Keerthana, P. Angadi","doi":"10.4103/kleuhsj.kleuhsj_580_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_580_22","url":null,"abstract":"Fibrolipoma is a benign neoplasm categorized as a histopathological variant of classical lipoma. The occurrence of fibrolipoma in the oral cavity is extremely rare. When present, it manifests as a pedunculated or sessile, soft, smooth-surfaced nodular mass. Although it may vary, the majority of lesions are <5 cm in size. There may be association between functional and aesthetic limitations related to anatomical sites. Hence, it is crucial to properly examine lipomas histopathologically for better treatment modalities. Here is a case report of fibrolipoma occurring in buccal mucosa.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"49 1","pages":"171 - 174"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80702675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_337_21
S. Lohitashwa, Srinidhi S. Hegde, K. Varghese, M. Srilakshmi, Sreekantha Sudaraghavan
Background: Assessment of the right chamber function has not given much importance; this could be due to complex structure, asymmetric shape, and difficulty in visualization, and resulted in poor understanding of the impact of the right ventricular (RV) function on prognosis. Echocardiography commonly used and most readily available investigation modality for the assessment of the right ventricular function. AIMS AND OBJECTIVES: The aim of this study was to evaluate the relation between RV function and left ventricle (LV) dysfunction and Killip class in acute myocardial infarction (AMI) exclusive of RV infarction. MATERIAL AND METHODS: A total of 21 consecutive patients admitted to the coronary care unit with AMI were included and echocardiography was performed within 24 h of admission to assess RV and LV functions. RV function was quantified with a tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC), RV longitudinal strain, RV myocardial performance index (RVMPI), and compared with the LV ejection fraction and Killip class. Results: Statistical analysis revealed that the majority of patients were male (90.5%) and only 9.5% of patients were female with a mean age of 50.9 years. Anterior wall MI was more common (58%) than inferior wall MI (42%). The study findings revealed that the RV longitudinal strain had a significant negative correlation (r2 = 0.803, P = 0.001) with Killip class and LV ejection fraction, whereas TAPSE, RVMPI, and RVFAC were poorly correlated with RV dysfunction. Conclusion: From the study findings, we concluded that echocardiographic assessment of RV functions demonstrated that larger infarcts correlated with RV dysfunction. RV involvement was more pronounced in anterior MI than inferior MI. Hence, the earliest recognition of RV dysfunction is warranted. Keywords: Acute myocardial infarction, echocardiograph, right ventricular function.
背景:对右心室功能的评估尚未得到重视;这可能是由于右心室结构复杂，形状不对称，难以可视化，导致对右心室(RV)功能对预后的影响了解不足。超声心动图是评估右心室功能最常用和最容易获得的调查方式。目的和目的:本研究的目的是评估急性心肌梗死(AMI)患者左心室功能与左心室功能障碍和Killip分级之间的关系。材料和方法:共纳入21例连续入住冠状动脉护理病房的AMI患者，并在入院24小时内进行超声心动图检查以评估左室和左室功能。采用三尖瓣环平面收缩偏移(TAPSE)、左室分数面积变化(RVFAC)、左室纵向应变、左室心肌功能指数(RVMPI)量化左室功能，并与左室射血分数和Killip分级进行比较。结果:统计分析显示，男性占90.5%，女性占9.5%，平均年龄50.9岁。前壁心肌梗死(58%)比下壁心肌梗死(42%)更为常见。研究结果显示，左室纵向应变与Killip分级和左室射血分数呈显著负相关(r2 = 0.803, P = 0.001)，而TAPSE、RVMPI和RVFAC与右室功能障碍相关性较差。结论:从研究结果中，我们得出结论，超声心动图对右心室功能的评估表明，较大的梗死与右心室功能障碍相关。左心室受累在心肌梗死前段比下段更为明显。因此，早期识别右心室功能障碍是有必要的。关键词:急性心肌梗死，超声心动图，右心室功能。
{"title":"Echocardiographic assessment of the right ventricular function in acute myocardial infarction","authors":"S. Lohitashwa, Srinidhi S. Hegde, K. Varghese, M. Srilakshmi, Sreekantha Sudaraghavan","doi":"10.4103/kleuhsj.kleuhsj_337_21","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_337_21","url":null,"abstract":"Background: Assessment of the right chamber function has not given much importance; this could be due to complex structure, asymmetric shape, and difficulty in visualization, and resulted in poor understanding of the impact of the right ventricular (RV) function on prognosis. Echocardiography commonly used and most readily available investigation modality for the assessment of the right ventricular function. AIMS AND OBJECTIVES: The aim of this study was to evaluate the relation between RV function and left ventricle (LV) dysfunction and Killip class in acute myocardial infarction (AMI) exclusive of RV infarction. MATERIAL AND METHODS: A total of 21 consecutive patients admitted to the coronary care unit with AMI were included and echocardiography was performed within 24 h of admission to assess RV and LV functions. RV function was quantified with a tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC), RV longitudinal strain, RV myocardial performance index (RVMPI), and compared with the LV ejection fraction and Killip class. Results: Statistical analysis revealed that the majority of patients were male (90.5%) and only 9.5% of patients were female with a mean age of 50.9 years. Anterior wall MI was more common (58%) than inferior wall MI (42%). The study findings revealed that the RV longitudinal strain had a significant negative correlation (r2 = 0.803, P = 0.001) with Killip class and LV ejection fraction, whereas TAPSE, RVMPI, and RVFAC were poorly correlated with RV dysfunction. Conclusion: From the study findings, we concluded that echocardiographic assessment of RV functions demonstrated that larger infarcts correlated with RV dysfunction. RV involvement was more pronounced in anterior MI than inferior MI. Hence, the earliest recognition of RV dysfunction is warranted. Keywords: Acute myocardial infarction, echocardiograph, right ventricular function.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"1 1","pages":"37 - 40"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88594038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_128_22
Swaran Lata, Varsha Singh, Anupriya
{"title":"HIV/acquired immune deficiency syndrome stigma, perceived social support, and medical adherence among HIV/acquired immune deficiency syndrome children: A mediation analysis","authors":"Swaran Lata, Varsha Singh, Anupriya","doi":"10.4103/kleuhsj.kleuhsj_128_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_128_22","url":null,"abstract":"","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78290363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_152_22
Milind Ubale, V. Nanoty, P. Patel, RajeshMahadeo Trimukhe, DebapriyaDas Choudhury, Pradnya S. Joshi
{"title":"A study of dermatophytosis in patients attending dermatology outdoor patient department at a tertiary care center","authors":"Milind Ubale, V. Nanoty, P. Patel, RajeshMahadeo Trimukhe, DebapriyaDas Choudhury, Pradnya S. Joshi","doi":"10.4103/kleuhsj.kleuhsj_152_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_152_22","url":null,"abstract":"","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75812745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_82_23
P. Angadi, H. Kour
{"title":"Influence of social media in research: Boon or bane","authors":"P. Angadi, H. Kour","doi":"10.4103/kleuhsj.kleuhsj_82_23","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_82_23","url":null,"abstract":"","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"71 1","pages":"4 - 6"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83913736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_492_22
Ruchi Srivastava, Anju Gautam
Gingival overgrowth is one of the most undesirable consequences that often lead to impaired esthetics and masticatory functions, compromised oral hygiene maintenance often requiring surgical excision of the excessive tissue. Gingival overgrowth belongs to a common group of lesions designated as focal reactive overgrowths. These growths are reactive in nature. A definitive diagnosis will then enable an appropriate management strategy. Peripheral giant-cell granuloma (PGCG) is a reactive focal overgrowth, ordinarily presents as an epulis-like growth. This is of a reactive rather than neoplastic nature and its pathogenesis is uncertain. It is widely considered to originate from the cells of the periodontal ligament, occurring as a response to irritants such as dental calculus, plaque, microorganisms, dental appliances, and restorations. The purpose of this article is to report the clinical, histopathological features and treatment of a case with PGCG arising from mandibular posterior alveolus in a 34-year-old female. The overgrowth was well defined along with the bone defect, involving the buccal aspect of the mandibular gingiva. The tooth was endodontically treated, the lesion was completely excised, and the osseous defect was filled with regenerative material. The 12-month follow-up radiograph revealed successful healing with no more recurrence.
{"title":"Rare presentation of localized gingival overgrowth with osseous defect – Case report","authors":"Ruchi Srivastava, Anju Gautam","doi":"10.4103/kleuhsj.kleuhsj_492_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_492_22","url":null,"abstract":"Gingival overgrowth is one of the most undesirable consequences that often lead to impaired esthetics and masticatory functions, compromised oral hygiene maintenance often requiring surgical excision of the excessive tissue. Gingival overgrowth belongs to a common group of lesions designated as focal reactive overgrowths. These growths are reactive in nature. A definitive diagnosis will then enable an appropriate management strategy. Peripheral giant-cell granuloma (PGCG) is a reactive focal overgrowth, ordinarily presents as an epulis-like growth. This is of a reactive rather than neoplastic nature and its pathogenesis is uncertain. It is widely considered to originate from the cells of the periodontal ligament, occurring as a response to irritants such as dental calculus, plaque, microorganisms, dental appliances, and restorations. The purpose of this article is to report the clinical, histopathological features and treatment of a case with PGCG arising from mandibular posterior alveolus in a 34-year-old female. The overgrowth was well defined along with the bone defect, involving the buccal aspect of the mandibular gingiva. The tooth was endodontically treated, the lesion was completely excised, and the osseous defect was filled with regenerative material. The 12-month follow-up radiograph revealed successful healing with no more recurrence.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":"32 1","pages":"159 - 162"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91168361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/kleuhsj.kleuhsj_489_22
Naren Rajendran, K. Sureshkumar, S. Kailash, Sivabackiya Chitravelu, Niha Rumaisa
BACKGROUND: Restricting the availability of alcohol in “dry states” and during the COVID-19 lockdown reveal illegal trading and consumption of illicit liquor leading to deaths and use of alternate harmful substances. The current study aims to fill the gaps in the literature to study alcohol usage and its procurement during its complete ban of sale. MATERIALS AND METHODS: A cross-sectional study of purposively sampled alcohol-dependent patients (n = 62) was conducted in an OPD setting, comparing two time periods: before and during total lockdown 2020. After reinforcing confidentiality and privacy, data were collected and analyzed. RESULTS: Alcohol usage during the lockdown was positively related to severity of alcohol dependence syndrome (r = 0.67, P = 0.00), quantity of alcohol consumed (r = 0.59, P = 0.00), and its cost of procurement (r = 0.43, P = 0.00) before lockdown. During the lockdown, the proportion of consuming alcohol more than or equal to 90 units weekly significantly decreased (Pearson Chi-square = 4.12, P = 0.04) and their predicting factors are rural residential location, moderate-income bracket, low socioeconomic class, and severe alcohol dependence. Furthermore, a significant increase in the proportion of procuring alcohol from the black market or used illicit liquor was observed (Fisher's exact test P = 0.00) with higher odds being associated with illegal procurement before lockdown (odds ratio = 22.00; 95% confidence interval = 3.93–123.28; P = 0.00). Increased use of alternate substances such as nicotine (37.1%) and cannabis (9.7%) during the lockdown was also observed. CONCLUSION: Although alcohol consumed did not significantly differ, illegal sources and money spent on procurement increased during the lockdown. Thus, a legal ban of liquor sales did not benefit alcohol dependence patients, and such restriction availability strategies may benefit from health awareness, treatment, and psychosocial support.
背景:在“干旱状态”和COVID-19封锁期间限制酒精供应，表明非法交易和消费非法酒精导致死亡和使用替代有害物质。目前的研究旨在填补文献中的空白，研究酒精的使用和在完全禁止销售期间的采购。材料和方法:在OPD环境中对有目的取样的酒精依赖患者(n = 62)进行了一项横断面研究，比较了两个时间段:2020年全面封锁之前和期间。在加强保密和隐私之后，收集和分析数据。结果:封城期间酒精使用与封城前酒精依赖综合征严重程度(r = 0.67, P = 0.00)、酒精消费量(r = 0.59, P = 0.00)和采购成本(r = 0.43, P = 0.00)呈正相关。在封城期间，每周饮酒量大于或等于90单位的比例显著下降(Pearson卡方= 4.12,P = 0.04)，其预测因素为农村居住地、中等收入阶层、低社会经济阶层和严重酒精依赖。此外，观察到从黑市购买酒精或使用非法酒的比例显著增加(Fisher确切检验P = 0.00)，与封锁前非法采购相关的几率更高(优势比= 22.00;95%置信区间= 3.93-123.28;P = 0.00)。还观察到，在封锁期间，尼古丁(37.1%)和大麻(9.7%)等替代物质的使用有所增加。结论:虽然酒精消费量没有显著差异，但在封锁期间，非法来源和用于采购的资金增加了。因此，法律禁止酒类销售对酒精依赖患者没有好处，而这种限制供应策略可能受益于健康意识、治疗和社会心理支持。
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