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A New Corneal Remodeling Technique with Laser Asymmetric Keratectomy Using Semi-Cylindrical Ablation Pattern Reducing Regional Asymmetry of Corneal Thickness, Case Series 一种新的角膜重塑技术:半圆柱形消融模式激光非对称角膜切除术,减少角膜厚度的区域不对称性,病例系列
Pub Date : 2022-07-04 DOI: 10.24966/ocr-8887/100091
Ji Sang Min, B. Min, Dong Cho Lee
Laser asymmetric keratectomy using semi-cylindrical ablation pattern (LAK-SCAP) is a new customized corneal remodeling method reducing regional asymmetry of corneal thickness, so could be to avoid and treat conventional laser refractive surgery adverse effects. Three eyes (3 patients) had laser epithelial keratomileusis (LASEK) linked LAK-SCAP (L-LAK-SCAP) to reduce regional asymmetry of corneal thickness and correct refractive errors. On Orbscan map, the cones of the corneas were located in the peripheral side, the corneal thickness imbalance was severe due to the sum of 4 direction differences in corneal thickness >80µm.
采用半圆柱形消融模式的激光非对称角膜切除术(lake - scap)是一种新的定制角膜重塑方法,可以减少角膜厚度的区域不对称性,从而避免和治疗传统激光屈光手术的不良反应。3眼(3例)行激光上皮性角膜磨除术(LASEK)联合LAK-SCAP (L-LAK-SCAP),以减少角膜厚度的区域不对称,矫正屈光不正。在Orbscan图上,角膜锥体位于外周侧,4个方向的角膜厚度差之和>80µm,导致角膜厚度失衡严重。
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引用次数: 0
Macular Thickness Measurement in Diabetic Patients Using Optical Coherence Tomography in Yaounde 在雅温得使用光学相干断层扫描测量糖尿病患者黄斑厚度
Pub Date : 2022-07-04 DOI: 10.24966/ocr-8887/100096
G. Kagmeni, C. Ngoune, C. Mvilongo, S. N. Nsala, C. Noche
85 diabetic patients were included (165 eyes). The mean age was 57.4 ± 9.4 years. The mean central macular thickness was 229.6 ± 53.8 µm. Optical coherence tomography detected a retinal abnormality in 78.2% of the eyes compared with 8.5% on fundoscopy. Abnormalities of macular thickness included perifoveolar thickening, macular thinning, subclinical macular edema and significant macular edema.
纳入85例糖尿病患者(165只眼)。平均年龄57.4±9.4岁。中心黄斑平均厚度为229.6±53.8µm。光学相干断层扫描在78.2%的眼睛中检测到视网膜异常,而眼底镜检查则为8.5%。黄斑厚度异常包括滤泡周围增厚、黄斑变薄、亚临床黄斑水肿和明显的黄斑水肿。
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引用次数: 0
Validation of a New Meibomian Gland Dysfunction (MGD) Grading Scale for Rapid Assessment of MGD in Clinical Practice 在临床实践中快速评估睑板腺功能障碍(MGD)分级量表的验证
Pub Date : 2022-07-04 DOI: 10.24966/ocr-8887/100094
Fahad Salem Alshahrani, F. Stapleton, B. Golebiowski, Emma Gibson, Archana Boga
This is the first study to validate the combination of TE for evaluating MGD. This study didn’t show correlations between TE combination against MGD14 and against meibography. In addition, there was no correlation between meibography and MGD14. Overall, this study displayed poor relationship between symptoms and signs of dry eye; however, these results need to be confirmed in a large sample size with more participants displaying MGD.
这是第一个验证TE联合评估MGD的研究。本研究未发现TE联合用药与MGD14和meibography之间存在相关性。此外,meibography与MGD14之间没有相关性。总的来说,这项研究显示干眼症的症状和体征之间的关系很差;然而,这些结果需要在更大的样本量中得到证实,更多的参与者表现为MGD。
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引用次数: 0
Longitudinal Evaluation of an Acute Nd:YAG Laser-Induced Macular Hole: A Case Report Nd:YAG激光致急性黄斑孔的纵向评价1例
Pub Date : 2022-07-04 DOI: 10.24966/ocr-8887/100095
Mauricio Bayram-Suverza, Elvia Isabel Vázquez-Ramírez, Manuel Angel Alcántara-Delgado, Julieta Villar-López
Macular Holes (MHs) caused by neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers are increasingly reported worldwide, but there is little experience with their management. Furthermore, longitudinal evaluations of their characteristics are scarce. Here, we describe the ophthalmologic findings and follow-up of a patient with an accidental Nd:YAG laser-induced MH. The patient attended with central scotoma of the right eye
由掺钕钇铝石榴石(Nd:YAG)激光器引起的黄斑孔(MHs)在世界范围内越来越多地被报道,但其管理经验很少。此外,缺乏对其特征的纵向评价。在这里,我们描述了一个意外的Nd:YAG激光诱导MH患者的眼科检查结果和随访。患者参加了右眼中央暗斑
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引用次数: 0
A Case of Ocular Ischaemic Syndrome Associated with Choroidal Folds 眼缺血综合征伴脉络膜皱褶1例
Pub Date : 2022-07-04 DOI: 10.24966/ocr-8887/100093
F. Kaya, E. Kasapoğlu, Umut Onur, Oznur Iscan, Ozgur Orum, F. U. Yigit
A 58 year-old male patient presented with fluctuating vision in right eye. Dilated fundus examination on presentation showed wavy choroidal folds and cotton wool spots in the posterior pole of right eye. Fundus fluorescein angiogram demonstrated prolonged arm-to-retina circulation time and a patchy choroidal filling pattern in the same eye
患者男,58岁,右眼视力波动。就诊时眼底扩张检查右眼后极可见波浪形脉络膜褶皱及棉絮斑。眼底荧光素血管造影显示手臂到视网膜循环时间延长,同一只眼睛有斑片状脉络膜充盈
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引用次数: 0
The Incidence and Etiology of 3rd, 4th, 6th, and Multiple Cranial Nerve Palsies in South India: A 6-Month Retrospective Prevalence Study 印度南部第3、4、6和多发性脑神经麻痹的发病率和病因:一项为期6个月的回顾性患病率研究
Pub Date : 2022-06-21 DOI: 10.33140/jocr.06.02.03
S. Habeel, Karthik Kumar, P. Macintosh, Virna M. Shah
Cranial nerve palsies may occur secondary to various etiologies including vasculopathic risk factors, trauma, cerebrovascular accident, neoplasms, inflammation, pituitary apoplexy, aneurysm and giant cell arteritis [1-6]. Studies have compared various etiologies in the West, Korea, and North India but data aimed at the South Indian population is limited. Geographic specific data can help in better understanding region specific risk factors.
脑神经麻痹可继发于多种病因,包括血管病变危险因素、外伤、脑血管意外、肿瘤、炎症、垂体中风、动脉瘤和巨细胞动脉炎[1-6]。研究比较了西方、韩国和北印度的各种病因,但针对南印度人口的数据有限。特定地理数据有助于更好地了解特定区域的风险因素。
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引用次数: 0
Epidemiological Study on Ocular Trauma and Associated Co-Morbidity at Tertiary Health Care Hospital 三级卫生保健医院眼外伤及相关合并症流行病学研究
Pub Date : 2022-06-21 DOI: 10.33140/jocr.06.02.02
S. Prabhakar, S. Maheshwari, HV Soumya, Anita T Girish, K. Kumar
Aims: To classify and find out the incidence of ocular injury effects and extraocular associates. Methods and Materials: This eight-month observational study was conducted between 2017 and 2018 recruiting 111 eyes of 101 patients reporting to ophthalmology outpatient and emergency medicine departments. Results: The demographic profile is composed of 82 (81.18%) males and 19 (18.81%) females with a mean presenting age of 33.45 and 33.57 years in males and females respectively ranging from 3 to 82 years. Sixty four (57.65%) right and 47 (42.34%) left eyes studied. Closed globe injuries accounted for 95 (85.56%) and open globe injuries were found in 16 (14.41%) eyes. Mode of injuries classified as RTA 37 (33.33%), RTA Self fall 26 (23.42%), metal-induced trauma in 9 (8.10%) and exposure to vegetative matter in 9 (8.10%), self fall at home/work in 6 (5.40%), assault in 4 (2.6%), sports-related injuries in 3 (2.7%), bull gore injuries in 3 (2.7%) and explosion injuries in 3 (2.7%) eyes. RTA and RTA self fall showed the highest relative risk and odds ratio among males compared to females. The relative risk ratio and odds ratio for RTA in males showed 0.63 and 0.31 respectively. Anterior segment injury effects were observed in all eyes and 21 (18.91%) eyes with posterior segment involvement. The associated facio-maxillary injury was seen in 58 (52.25%) eyes, orbital wall fractures in 52 (46.85%), and head injury in 26 (23.42%) eyes. Thirty (35.14%) eyes required imaging for further evaluation, of which 32 (31.68%) underwent computed tomography and 2 (1.99%) eyes subjected to magnetic resonance imaging. Fifty-three (52.47%) eyes were managed surgically, 25 (24.75%) conservatively and 23 (22.77%) medically. Conclusion: This study analysis concludes that closed globe injury is the most common ocular trauma. In middle-aged male patients, RTA-induced injuries were commonly prevalent. The most frequently associated co-morbidities were facio-maxillary trauma, lateral orbital wall fractures, and subconjunctival hemorrhage. Maximum eyes required surgical management while computed tomography provided a conventional mode of imaging. The multi-departmental management approach is essential for achieving a good medical and surgical outcome.
目的:对眼损伤的发生率及眼外相关因素进行分类和分析。方法与材料:本研究于2017年至2018年进行,为期8个月,招募了101例眼科门急诊患者的111只眼睛。结果:男性82例(81.18%),女性19例(18.81%),男性和女性平均发病年龄分别为33.45岁和33.57岁,年龄在3 ~ 82岁之间。右眼64只(57.65%),左眼47只(42.34%)。闭合性眼球损伤95例(85.56%),开放性眼球损伤16例(14.41%)。损伤类型为RTA 37例(33.33%)、RTA自摔26例(23.42%)、金属性外伤9例(8.10%)、植物性接触9例(8.10%)、在家/工作中自摔6例(5.40%)、殴打4例(2.6%)、运动相关损伤3例(2.7%)、公牛角伤3例(2.7%)和爆炸伤3例(2.7%)。与女性相比,男性的RTA和RTA自我跌倒的相对风险和优势比最高。男性RTA的相对危险比和优势比分别为0.63和0.31。所有眼均有前段损伤,后段受累21眼(18.91%)。面颌损伤58例(52.25%)眼,眶壁骨折52例(46.85%)眼,头部损伤26例(23.42%)眼。30只(35.14%)眼需要影像学进一步评估,其中32只(31.68%)眼行计算机断层扫描,2只(1.99%)眼行磁共振成像。手术治疗53例(52.47%),保守治疗25例(24.75%),内科治疗23例(22.77%)。结论:闭合性眼球损伤是最常见的眼外伤。在中年男性患者中,rta引起的损伤普遍存在。最常见的合并症是颌面外伤、眶外侧壁骨折和结膜下出血。大多数眼睛需要手术治疗,而计算机断层扫描提供了传统的成像模式。多部门管理方法对于取得良好的医疗和手术效果至关重要。
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引用次数: 0
Efficacy of Posterior Scleral Reinforcement in Children with High Myopia: A Systematic Review and Meta-Analysis 后巩膜加固治疗儿童高度近视的疗效:系统回顾和meta分析
Pub Date : 2022-05-27 DOI: 10.33140/jocr.06.02.01
Purpose: The purpose of this meta-analysis is to evaluate the effect of posterior scleral reinforcement (PSR) on axial length (AL), spherical equivalents (SE) and best corrected visual acuity (BCVA) in children with high myopia. Methods: The databases PubMed, EMBASE, Wanfang Database, CNKI, CSTJ and Cochrane Library from inception to March 2021 were searched to identify the relevant studies which evaluated the efficacy of PSR for patients under 18 years old with high myopia. The main parameters include AL, SE and BCVA. Revman software version 5.3 was used to perform the statistical analyses. Results in proportion with 95% confidence interval were calculated using dersimonian-laird model. Results: 8 studies including 383 PSR treated and 281 control eyes were finally included. Our analysis indicated that PSR could slow down the increase of AL and the loss of vision loss (P<.01). However, in the subgroup with a follow-up period shorter than three years, there was no statistical difference in BCVA changes between the PSR and control groups (WMD=-0.02, 95%CI -0.07 to 0.04, P=.58, I2=0%). The BCVA changes is significant after 3 years follow up (WMD=-0.13, 95%Cl -0.21 to -0.05, P=0.007). Conclusion: PSR can benefit children in controlling the growth of AL, SE and decrease of visual acuity. 3 years after PSR may be a critical time point. Given the limitations in our study, more research with larger sample sizes and more accurate data are required to reach a firmer conclusion.
目的:本meta分析的目的是评价后巩膜加固(PSR)对高度近视儿童眼轴长(AL)、眼球面等效物(SE)和最佳矫正视力(BCVA)的影响。方法:检索PubMed、EMBASE、万方数据库、中国知网、CSTJ、Cochrane图书馆自成立以来至2021年3月间评价PSR治疗18岁以下高度近视患者疗效的相关研究。主要参数包括AL、SE和BCVA。采用Revman 5.3版软件进行统计分析。采用dersimonan -laird模型计算结果与95%置信区间的比例。结果:最终纳入8项研究,包括383只PSR治疗眼和281只对照眼。我们的分析表明,PSR可以减缓AL的增加和视力丧失(P< 0.01)。然而,在随访期小于3年的亚组中,PSR组与对照组的BCVA变化无统计学差异(WMD=-0.02, 95%CI = -0.07 ~ 0.04, P=。58岁的I2 = 0%)。随访3年后BCVA变化显著(WMD=-0.13, 95%Cl = -0.21 ~ -0.05, P=0.007)。结论:PSR对儿童AL、SE的生长及视力下降有一定的控制作用。PSR后的3年可能是一个关键的时间点。鉴于我们研究的局限性,需要更多的研究,更大的样本量和更准确的数据来得出更确切的结论。
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引用次数: 0
A Model to Assess Time to Treatment in Children with Optic Pathway Gliomas 评估儿童视神经胶质瘤治疗时间的模型
Pub Date : 2022-02-09 DOI: 10.33140/jocr.06.01.01
The objective of the present study is to identify factors that may be of prognostic value to predict the need for chemotherapy in paediatric patients with optic pathway gliomas (OPGs) and to propose a screening protocol where the hazard rate for the time from diagnosis to initiation of therapy can be estimated in each patient individually. A search in the national Low Grade Glioma (LGG) database was performed allowing identification of 93 children with OPGs from 21 participating centers in the UK. A variable selection procedure based on stepwise regression was applied to identify the significant risk factors that are of prognostic value to predict the need for treatment. A Receiver Operating Characteristic (ROC) curve was used to determine the optimal threshold for classifying the patients. The influence of the available risk factors on the time from diagnosis to initiation of therapy was assessed by a Cox proportional hazards model. Children without Neurofibromatosis type 1 (NF 1) were more likely to have tumour involvement of the most posterior visual pathway. Children with posterior tumour involvement and subjects with poor visual acuity (VA) and younger age at diagnosis were found to be the groups with the highest risk of receiving treatment. Three diagnostic groups (high, moderate, and low risk) were defined with respect to their estimated probability of receiving treatment. Individualized hazard function plots and point estimations for the probability of the need of treatment may modify the frequency and duration of follow-up evaluations in OPG patients.
本研究的目的是确定可能具有预后价值的因素,以预测患有视神经胶质瘤(OPGs)的儿科患者是否需要化疗,并提出一种筛查方案,在该方案中,从诊断到开始治疗的危险率可以在每个患者中单独估计。在国家低级别胶质瘤(LGG)数据库中进行了搜索,允许识别来自英国21个参与中心的93名患有opg的儿童。采用基于逐步回归的变量选择程序来确定具有预测治疗需要的预后价值的重要危险因素。采用受试者工作特征(ROC)曲线确定患者分类的最佳阈值。可用的危险因素对从诊断到开始治疗时间的影响通过Cox比例风险模型进行评估。无1型神经纤维瘤病(NF - 1)的儿童更容易肿瘤累及最后视通路。儿童后侧肿瘤受累,视力差(VA)和诊断时年龄较小的受试者被发现是接受治疗的最高风险群体。根据他们接受治疗的估计概率,定义了三个诊断组(高、中、低风险)。个性化的危险函数图和治疗需要概率的点估计可能会改变OPG患者随访评估的频率和持续时间。
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引用次数: 0
Use of Transscleral Laser in the Management of Glaucoma – Ophthalmology 经巩膜激光在青光眼治疗中的应用
Pub Date : 2022-02-09 DOI: 10.33140/jocr.06.01.02
Glaucoma is a pathology classed in the neuropathologies presented to the optic degree, of a chronic nature that structurally damages the connective tissue of the optic nerve head, in the presence of decreased neural tissue, where a progressive loss of nerve fibers is generated. The retina, excavation of the same and pallor of the pupil and consequently the beginning of usable deterioration, affecting the visual field, associated in most cases with alterations in intraocular pressure related to the development, progression and severity of the same. The drainage mechanism of the eye is located in the anterior part of the chamber angle, which in classic conditions is delegated from drainage of 83% to 93% through the different channels such as Schlemn’s canal, the trabecular meshwork, the intrascleral canals, and both episcleral and conjunctival veins, in addition there are secondary drainage pathways which are a mechanism named uveoscleral drainage system which are delegated to drain the rest of the humor. Cyclophotocoagulation is an appropriate treatment option for the treatment of painful and refractory absolute glaucoma, since it preserves the ocular anatomy, relieves symptoms and reports improvements in intraocular pressure and the symptoms presented in these patients in post-intervention monitoring
青光眼是一种视神经病理,具有慢性性质,在神经组织减少的情况下,视神经头结缔组织结构受损,神经纤维逐渐丧失。视网膜,视网膜的挖掘和瞳孔的苍白,并因此开始可用的退化,影响视野,在大多数情况下与眼压的改变有关,这与视网膜的发展,进展和严重程度有关。眼的引流机制位于腔角前部,经典情况下,引流率为83% - 93%,通过Schlemn管、小梁网、巩膜内管、膜外和结膜静脉等不同的通道,此外还有次要的引流途径,称为巩膜引流系统,负责引流其余的幽默。光凝治疗是治疗疼痛性难治性绝对青光眼的一种合适的治疗选择,因为它保留了眼部解剖结构,缓解了症状,并在干预后监测中报告了这些患者眼压和症状的改善
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引用次数: 0
期刊
Journal of Ophthalmology &amp; Clinical Research
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