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Is Group and Saving Before the Modern Bipolar Transurethral Resection of the Prostate Still Necessary? 现代双极经尿道前列腺切除术前的分组和保存是否仍有必要?
Pub Date : 2022-08-26 DOI: 10.22374/jeleu.v5i2.150
L. Kretzmer, A. Damola, Chloe Libotte, S. Ehsanullah, A. Jones, I. Apakama
Introduction: Group and save (G&S) sampling is commonplace for patients undergoing transurethral resection of the prostate (TURP) due to the historically high risk of bleeding. However, modern adjustments to the procedure, including the advent of bipolar TURP in saline, have significantly reduced this risk. This study assessed whether routinely performing G&Ss before the modern TURP is still appropriate. Materials and Methods: This study was a retrospective review of all patients who underwent a TURP from January 2009 until December 2019 in one centre. A total of 687 patients were identified during this period. In addition, data was collected on G&S samples, blood products, and postoperative complications such as clot retention or if patients required a blood transfusion. Results: All patients had G&S samples taken before their operation. Only six (0.87%) patients required a blood transfusion. Half were transfused intra-operatively and half post-operatively. Remarkably, none of the transfused patients were below the National Institute for Health and Care Excellence (NICE) threshold to transfuse of <70g/L(8). Six patients were also noted to develop clot retention following the catheter removal. Discussion and Conclusion: This study has determined that patients undergoing a TURP rarely require blood transfusions. We propose that the practice of routinely taking G&S samples before this procedure should be reviewed. This would give a financial benefit and relieve patients of the unnecessary test. We would recommend thorough optimisation of patients before surgery, including review of anticoagulation and correction of any preoperative anaemia.
简介:由于历史上出血的高风险,对于接受经尿道前列腺切除术(TURP)的患者,分组和保存(G&S)抽样是常见的。然而,现代对手术的调整,包括生理盐水双相TURP的出现,已经显著降低了这种风险。本研究评估了在现代TURP之前常规进行g&s是否仍然合适。材料和方法:本研究是对2009年1月至2019年12月在一个中心接受TURP的所有患者的回顾性研究。在此期间共发现687例患者。此外,还收集了G&S样本、血液制品和术后并发症(如血块保留或患者是否需要输血)的数据。结果:所有患者术前均采集G&S标本。只有6例(0.87%)患者需要输血。一半在术中输血,一半在术后输血。值得注意的是,没有一个输血患者低于国家健康与护理卓越研究所(NICE) <70g/L的输血阈值(8)。6例患者在拔除导管后出现血栓潴留。讨论和结论:本研究已经确定,接受TURP的患者很少需要输血。我们建议在此程序之前常规取样G&S样品的做法应该进行审查。这将带来经济上的好处,并减轻患者不必要的检查。我们建议术前对患者进行彻底的优化,包括抗凝检查和术前贫血的纠正。
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引用次数: 0
Successful Simultaneous Clearance of Bilateral Staghorn Stones with Flexible Uretero-Renoscopic Lasertripsy 柔性输尿管-肾镜激光术同时成功清除双侧鹿角结石
Pub Date : 2022-07-07 DOI: 10.22374/jeleu.v5i2.140
A. Kodera, Tara Burnhope, V. Koo
A 50-year-old tetraplegic gentleman was referred with visible haematuria and recurrent urinary tract infections (UTI) presenting as behavioural difficulty. His past medical history includes diffuse brain injury following a motorbike accident, hypertension, BMI 41, performance status 4, and needing a hoist for transfer. CT showed bilateral staghorn complete calculi measuring the maximum length of 3 cm (left) and 4.2 cm (right) with 600 HU. Following best interest meetings, the patient communicated his unwillingness to proceed with PCNL or open surgery due to risks and opted for FURS. His bilateral staghorn stone was completely cleared simultaneously at his primary procedure after a total operative time of 190 min. He had no postoperative complications and was discharged with bilateral stents in situ. He had a second-look FURS 4 weeks later but only required washout of minimal dust and removal of bilateral ureteric stents. His stone analysis confirmed struvite stone. His haematuria, recurrent UTIs, and behavioural issues were resolved. His 6 months postoperative CTKUB showed a dust-free status. This report discusses the challenges of simultaneous bilateral staghorn clearance using FURS.
一个50岁的四肢瘫痪的绅士被转介可见血尿和复发性尿路感染(UTI)表现为行为困难。既往病史包括摩托车事故后弥漫性脑损伤,高血压,BMI 41,运动状态4,需要起重机转移。CT示双侧鹿角型完整结石,最大长度3cm(左),4.2 cm(右),600 HU。在最佳利益会议之后,由于风险,患者表示不愿意进行PCNL或开放手术,并选择FURS。他的双侧鹿角结石在一次手术中完全清除,总手术时间为190分钟。他没有术后并发症,出院时双侧支架原位放置。4周后,他进行了第二次检查,但只需要冲洗少量灰尘并取出双侧输尿管支架。他的石头分析证实是鸟粪石。他的血尿、复发性尿路感染和行为问题得到解决。术后6个月CTKUB显示无尘状态。本报告讨论了使用FURS同时清除双边鹿角的挑战。
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引用次数: 0
Bladder Xanthoma
Pub Date : 2022-07-07 DOI: 10.22374/jeleu.v5i2.151
T. Ameen, Jong Seok Ahn, J. Carton, W. Hwang, Hama Attar
A 35-year-old male presented with multiple interrupted episodes of frank hematuria and persistent microscopic hematuria. CT urogram demonstrated a nonspecific lesion in the bladder. Cystoscopy showed a lesion in the bladder wall that was biopsied, and histopathology confirmed a xanthoma, a rare diagnosis in the bladder. This case report performs a review of current literature and examines necessary investigations,differential diagnoses, and management required for bladder xanthoma.
一名35岁男性,表现为多次间断的明显血尿和持续性镜下血尿。CT尿路图显示膀胱非特异性病变。膀胱镜检查显示膀胱壁病变,组织病理学证实为黄色瘤,这在膀胱中是罕见的诊断。本病例报告回顾了目前的文献,并探讨了必要的调查、鉴别诊断和膀胱黄瘤所需的治疗。
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引用次数: 0
Complicated Renal Cyst as a Cause of Renal Colic and its Endoscopic Treatment 致肾绞痛的复杂性肾囊肿及其内镜治疗
Pub Date : 2022-06-29 DOI: 10.22374/jeleu.v5i2.146
G. Astroza, Francisca Sepúlveda
Renal cysts have a prevalence of 10% in the general population. Although they are usually asymptomatic, around 8% will develop complications such as cystic infection. A 75-year-old female presented with flank pain and hematuria. Computed tomography showed a dominant cyst with connection with the excretory system, as well as ipsilateral hydronephrosis secondary to pyelo-ureteral obstruction. A double J catheter was installed, and antibiotic treatment was started. One month later, she was admitted for ureterorenoscopy which revealed communication between the main cyst and the urinary tract, and proceeded to performendoscopic drainage of the cyst.
一般人群中肾囊肿的患病率为10%。虽然他们通常是无症状的,但约8%的人会出现并发症,如囊性感染。一名75岁女性,表现为腹部疼痛和血尿。计算机断层扫描显示一个显性囊肿与排泄系统相连,以及继发于肾盂输尿管梗阻的同侧肾积水。置双J型导管,并开始抗生素治疗。1个月后,患者行输尿管镜检查,发现主囊肿与尿路相通,并行内镜下囊肿引流术。
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引用次数: 0
Urethral Surveillance after Radical Cystectomy 根治性膀胱切除术后尿道监测
Pub Date : 2022-06-22 DOI: 10.22374/jeleu.v5i1.142
T. Burnhope, M. Kitchen, A. Chakravarti, D. Mak, I. Wharton, West Midlands Urology Research Collaborative
Radical cystectomy (RC) is commonly performed with curative intent for primary or recurrent high-risk non-muscle-invasive and muscle-invasive bladder cancers. Urethral recurrence (UR) within the residual urethra, often proximally where the epithelial lining comprises urothelial cells, is a rare but well-described occurrence associated with adverse clinical outcomes. Current national guidelines therefore suggest that male patients with a defunctioned urethra should undergo annual endoscopic or urethral washing surveillance for 5 years following RC, to identify UR early, where local disease management (e.g., urethrectomy) may still be possible. Anecdotally, however, urethroscopy and urethral washing cytology appear to be infrequently performed. Our regional trainee-led research collaborative evaluated the frequency and tim-ing of urethral surveillance in the West Midlands in comparison to National Institute for Health and Care Excellence (NICE) guidelines. Patients and methodsOur 10-year cross-sectional retrospective regional analysis included 495 patients from 2008–2018. Clinical and demographic data were collected alongside cross-sectional staging and imaging, and timings and frequency of urethral endoscopic surveillance or urethral washing cytology. ResultsOverall, 159 (35.2%) patients received one (or more) surveillance urethroscopy. A minority of surveillance urethroscopies were annual, with hugely variable frequency or intervals ranging from every 4–50 months. Only 81 (19.6%) patients had urethral surveillance in keeping with the frequency suggested by NICE guidelines. At 10 years, disease-specific mortality was 42.0%, and overall or all-cause mortality was 44.7%. The overall UR rate (as detected by staging CT and/or urethroscopy) was 1.0% (n = 4); all four cases of UR were found in patients with positive urethral margins after RC who did not undergo immediate urethrectomy. ConclusionsOur regional urethral surveillance practice following RC is heterogeneous and suboptimal in comparison to NICE guidelines. Our UR rate was so low that we are unable to assert whether early detection has any clinical benefit, and therefore we cannot advocate routine urethral surveillance, but suggest that patients with positive urethral margins should be offered immediate urethrectomy post RC. In addition, we encourage collaborative urological research and data collection to generate higher volume series, more representative and generalisable data, and more meaningful conclusions.
根治性膀胱切除术(RC)通常用于原发性或复发的高风险非肌浸润性和肌浸润性膀胱癌。残留尿道内的尿道复发(UR),通常发生在上皮上皮细胞组成的近端,是一种罕见但描述良好的与不良临床结果相关的发生。因此,目前的国家指南建议,尿道功能障碍的男性患者应在尿道切除术后5年内每年接受内镜或尿道冲洗监测,以早期发现尿路,在局部疾病治疗(如尿道切除术)仍有可能的情况下。然而,有趣的是,尿道镜检查和尿道冲洗细胞学检查似乎很少进行。我们的区域培训生领导的研究合作评估了尿道口监测的频率和时间在西米德兰兹郡与国家健康和护理卓越研究所(NICE)的指导方针进行比较。患者和方法我们对2008-2018年的495例患者进行了10年的横断面回顾性区域分析。临床和人口统计数据与横断面分期和成像、尿道内窥镜检查或尿道冲洗细胞学检查的时间和频率一起收集。结果159例(35.2%)患者接受了一次(或多次)尿道镜检查。少数尿道镜检查每年进行一次,频率或间隔变化很大,从每4-50个月不等。只有81例(19.6%)患者进行了符合NICE指南建议频率的尿道监测。10年时,疾病特异性死亡率为42.0%,总体或全因死亡率为44.7%。总UR率(通过分期CT和/或尿道镜检查)为1.0% (n = 4);所有4例尿路均发生在尿道边缘呈阳性且未立即行尿道切除术的患者中。结论与NICE指南相比,RC术后区域尿道监测实践存在异质性和次优性。我们的尿路发生率很低,因此我们不能断言早期发现是否有任何临床益处,因此我们不能提倡常规尿道监测,但建议尿道边缘呈阳性的患者在RC后应立即行尿道切除术。此外,我们鼓励合作泌尿学研究和数据收集,以产生更大的体积系列,更具代表性和普遍性的数据,和更有意义的结论。
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引用次数: 0
The Use of Spinal Anaesthesia for Retrograde Uretero-Renoscopy during the COVID-19 Pandemic COVID-19大流行期间脊髓麻醉在逆行输尿管-肾镜检查中的应用
Pub Date : 2022-06-01 DOI: 10.22374/jeleu.v5.1.138
W. Gallagher, Anna Longshaw, A. Dickinson
BackgroundThe use of spinal anaesthesia (SA) for retrograde uretero-renoscopic surgery is considered to be not as effective as a general anaesthetic (GA) by urologists. However, there were significant concerns associated with GA both for the patient and the anaesthetic team at the height of the COVID-19 pandemic. Our unit was able to successfully transfer surgery to a purpose-built day facility that had extensive experience in delivering SA. This created the opportunity to assess the SA technique in uretero-renoscopy in a cohort of unselected patients. ObjectiveTo assess the feasibility of SA as a primary form of anaesthetic for retrograde endoluminal renal and ure-teric surgery. ResultsOver 4 months, 41 ureteroscopic procedures were performed. The conversion rate to GA (for inadequate analgesia) was 9.8%. Surgical outcome data were compared with an equivalent cohort of patients’ who underwent GA before the pandemic. Both groups had similar outcomes: day-case discharge rate (SA 84%, GA 86%) and surgical completion rate (SA 94%, GA 90%). However, there was a difference in post-operative readmission rate (SA 8%, GA 22%) favouring SA. ConclusionsThis observational study demonstrated that SA is a safe and effective form of anaesthesia for uretero-renoscopic surgery, delivering non-inferior outcomes to GA. This has implications for the immediate provision of care as COVID-19 continues and as an alternative anaesthetic option to suit patients post pandemic. A larger pro-spective observational study would be appropriate to clearly define the benefits of SA for ureteroscopy.
背景:泌尿科医生认为在逆行输尿管镜手术中使用脊髓麻醉(SA)不如全身麻醉(GA)有效。然而,在COVID-19大流行高峰期,患者和麻醉团队都对GA存在重大担忧。我们的单位能够成功地将手术转移到一个专门建造的日间设施,该设施在提供SA方面具有丰富的经验。这为在一组未选择的患者中评估输尿管-肾镜检查中的SA技术创造了机会。目的探讨SA作为逆行腔内肾及腹腔手术主要麻醉形式的可行性。结果4个月内共行输尿管镜41例。转换率为GA(止痛不充分)为9.8%。将手术结果数据与大流行前接受GA的等效队列患者进行比较。两组的结果相似:日出院率(SA 84%, GA 86%)和手术完成率(SA 94%, GA 90%)。然而,SA组在术后再入院率(SA 8%, GA 22%)方面存在差异。结论:本观察性研究表明,在输尿管镜手术中,SA是一种安全有效的麻醉形式,其麻醉效果优于GA。这对在COVID-19持续期间立即提供护理以及作为大流行后适合患者的另一种麻醉选择具有影响。一项更大的前瞻性观察性研究将适合明确定义输尿管镜下SA的益处。
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引用次数: 0
Proceedings of the Welsh Urological Society 威尔士泌尿学会学报
Pub Date : 2022-05-25 DOI: 10.22374/jeleu.v5i2.148
G. Kandaswamy
Proceedings of the Welsh Urological Society 28th & 29th April 2022Hensol, Pontyclun
威尔士泌尿学会学报,2022年4月28日和29日,hensol, Pontyclun
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引用次数: 0
An Unexpected Finding in a Patient with Suspected Urothelial Recurrence during Surveillance Post Radical Cystoprostatectomy for Urothelial Bladder Carcinoma 一例尿路上皮性膀胱癌根治性膀胱前列腺切除术后监测中怀疑尿路上皮复发的意外发现
Pub Date : 2022-03-24 DOI: 10.22374/jeleu.v5i1.129
Ibrahim Alkhafaji, Harmony Uwadiae, Hajir Al-Hashimi, E. Abusada, S. Srirangam, Omar Al-Mula Abed
We report a 79-year-old gentleman with an asymptomatic intra-ureteric encrusted suture thread. He was found to have calcification in the left renal pelvis and thickening of the upper ureteric wall on a follow-up computerised tomography (CT) scan ten years after a radical cystoprostatectomy and ileal conduit formation for bladder and prostate cancer. These incidental CT scan findings raised the possibility of either ureteric stone or tumour. Subsequently, the patient underwent a ureterorenoscopy, which revealed a calcified 6cm length thread thought to be a suture that slipped intraoperative during his initial radical surgery ten years earlier.
我们报告一位79岁的男士,无症状输尿管内包覆缝线。患者因膀胱癌和前列腺癌行根治性膀胱前列腺切除术和回肠导管形成手术十年后,在随访的计算机断层扫描(CT)中发现左肾盂钙化和输尿管上壁增厚。这些偶然的CT扫描结果提示输尿管结石或肿瘤的可能性。随后,患者接受输尿管镜检查,发现一根钙化的6厘米长的线被认为是缝合线,该缝合线在10年前的首次根治性手术中滑落。
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引用次数: 0
Bladder Melanosis 膀胱黑变病
Pub Date : 2022-02-21 DOI: 10.22374/jeleu.v5i1.136
D. Hogan, Nick Meyer, D. Hennessey
This case report describes a rare cystoscopic finding in an octogenarian, presenting initially with nonspecific lower urinary tract symptoms. Physical examination did not reveal any abnormal skin or mucoepi-dermoid pigmentation. Routine ultrasound identified cystic changes in the bladder prompting cystoscopic investigation. Flexible cystoscopy identified melanin deposits within the bladder mucosa, and biopsy subsequently confirmed a diagnosis of bladder melanosis. The authors of this report wish to add to the available literature on this extremely rare finding in the hope a more robust evidence base would allow a protocol to be established for follow-up. The ultrasound findings reported in this study have not been previouslyreported and may benefit future guidelines on diagnosis.
这个病例报告描述了一个罕见的膀胱镜发现在八十多岁,最初表现为非特异性下尿路症状。体格检查未发现任何异常皮肤或粘膜表皮样色素沉着。常规超声检查发现膀胱囊性改变,提示膀胱镜检查。柔性膀胱镜检查发现膀胱粘膜内黑色素沉积,活检随后证实膀胱黑色素病的诊断。本报告的作者希望补充关于这一极其罕见的发现的现有文献,希望有一个更有力的证据基础,以便制定后续行动的议定书。本研究报告的超声结果以前没有报道过,可能有助于未来的诊断指南。
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引用次数: 0
Primary Ureteric Stent Insertion Under Local Anaesthetic or Sedoanalgesia in Non-pregnancy 非妊娠期局部麻醉或sedo镇痛下输尿管支架置入术
Pub Date : 2022-02-21 DOI: 10.22374/jeleu.v5i1.137
J. Gabriel, M. Quraishi, B. Osman, L. Shafik, Abraham Gabriel, G. Watson, S. Mackie
Background and ObjectiveTo characterise the evidence surrounding local anaesthetic ureteric stent insertion (LAUSI) in contexts outside of pregnancy, a procedure typically performed under general anaesthetic (GAUSI), as it has never been the subject of a systematic review.Materials and MethodsA systematic review of the Medline, EMBASE, PubMed, AMED, BNI, EMCARE, HMIC and PsycINFO databases was conducted to examine the published evidence in line with the Preferred Reporting Items of Systematic Review and Meta-analyses (PRISMA) guidelines surrounding the technique, patient demographics, setting, type of LA± sedoanalgesia used, cystoscopy and fluoroscopy usage, patient tolerability and pain, efficacy, complications and cost-effectiveness. Around 1,460 papers were systematically screened for inclusion.ResultsSeventeen studies were identified; one randomised controlled trials (RCT), four non-randomised com-parative studies, and 12 case-series describing LAUSI. The 17 studies encompassed a total of some 1545 LAUSI. The clinical indications were similar to those for GAUSI. Successful LAUSI rate ranged from 71-98.9% in studies overall, with a pooled mean success rate of 89.3% overall (86.8% in LA only, 91.75% in LA ± sedoanalgesia). The tolerability of a LAUSI patient across 14 studies had a pooled mean rate of 91.8% (88.6% in LA only, 95% in LA ± sedoanalgesia). The procedure time was reported in seven studies, and it ranged from 5.35±0.87 to 65.0±27.5 minutes. The four comparative studies showed no difference in complication rates between LAUSI and GAUSI. All five studies reporting on cost-effectiveness showed LAUSI to be superior to GAUSI.ConclusionsLAUSI is a safe, effective, and cost-effective alternative to GAUSI, which is underutilised. Further research in the form of RCTs is required to formally establish its place and acceptability amongst urologists.
背景与目的描述妊娠外输尿管局部麻醉支架置入(LAUSI)的相关证据,这是一种通常在全身麻醉(GAUSI)下进行的手术,因为它从未成为系统综述的主题。材料和方法对Medline、EMBASE、PubMed、AMED、BNI、EMCARE、HMIC和PsycINFO数据库进行了系统回顾,根据系统回顾和荟萃分析(PRISMA)指南的首选报告项目,围绕技术、患者人口统计学、环境、使用的LA±sedo镇痛药类型、膀胱镜和透视镜使用、患者耐受性和疼痛、疗效、并发症和成本效益,检查已发表的证据。大约1460篇论文被系统筛选纳入。结果共纳入17项研究;1项随机对照试验(RCT)、4项非随机对照研究和12个描述LAUSI的病例系列。这17项研究共涉及约1545个LAUSI。临床适应症与GAUSI相似。所有研究的LAUSI成功率为71-98.9%,总体平均成功率为89.3%(仅LA为86.8%,LA±sedo镇痛为91.75%)。在14项研究中,LAUSI患者的耐受性汇总平均率为91.8%(仅LA为88.6%,LA±sedo镇痛为95%)。7项研究报告了手术时间,范围为5.35±0.87至65.0±27.5分钟。四项比较研究显示LAUSI和GAUSI的并发症发生率无差异。报告成本效益的所有五项研究均显示LAUSI优于GAUSI。结论slausi是一种安全、有效、经济的替代GAUSI的方法,但未得到充分利用。需要以随机对照试验的形式进行进一步的研究,以正式确定其在泌尿科医生中的地位和可接受性。
{"title":"Primary Ureteric Stent Insertion Under Local Anaesthetic or Sedoanalgesia in Non-pregnancy","authors":"J. Gabriel, M. Quraishi, B. Osman, L. Shafik, Abraham Gabriel, G. Watson, S. Mackie","doi":"10.22374/jeleu.v5i1.137","DOIUrl":"https://doi.org/10.22374/jeleu.v5i1.137","url":null,"abstract":"Background and ObjectiveTo characterise the evidence surrounding local anaesthetic ureteric stent insertion (LAUSI) in contexts outside of pregnancy, a procedure typically performed under general anaesthetic (GAUSI), as it has never been the subject of a systematic review.Materials and MethodsA systematic review of the Medline, EMBASE, PubMed, AMED, BNI, EMCARE, HMIC and PsycINFO databases was conducted to examine the published evidence in line with the Preferred Reporting Items of Systematic Review and Meta-analyses (PRISMA) guidelines surrounding the technique, patient demographics, setting, type of LA± sedoanalgesia used, cystoscopy and fluoroscopy usage, patient tolerability and pain, efficacy, complications and cost-effectiveness. Around 1,460 papers were systematically screened for inclusion.ResultsSeventeen studies were identified; one randomised controlled trials (RCT), four non-randomised com-parative studies, and 12 case-series describing LAUSI. The 17 studies encompassed a total of some 1545 LAUSI. The clinical indications were similar to those for GAUSI. Successful LAUSI rate ranged from 71-98.9% in studies overall, with a pooled mean success rate of 89.3% overall (86.8% in LA only, 91.75% in LA ± sedoanalgesia). The tolerability of a LAUSI patient across 14 studies had a pooled mean rate of 91.8% (88.6% in LA only, 95% in LA ± sedoanalgesia). The procedure time was reported in seven studies, and it ranged from 5.35±0.87 to 65.0±27.5 minutes. The four comparative studies showed no difference in complication rates between LAUSI and GAUSI. All five studies reporting on cost-effectiveness showed LAUSI to be superior to GAUSI.ConclusionsLAUSI is a safe, effective, and cost-effective alternative to GAUSI, which is underutilised. Further research in the form of RCTs is required to formally establish its place and acceptability amongst urologists.","PeriodicalId":136362,"journal":{"name":"Journal of Endoluminal Endourology","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126286051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Journal of Endoluminal Endourology
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