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Simulating the stress-strain state of a thin plate after a thermal shock 模拟热冲击后薄板的应力-应变状态
Pub Date : 2021-11-29 DOI: 10.1142/s1793962322500246
A. Sedelnikov, S. Glushkov, V. Serdakova, M. Evtushenko, E. Khnyryova
The paper is devoted to simulating the impact of a thermal shock on a thin homogeneous plate in the ANSYS package. The assessment of the stress–strain state is carried out and the dynamics of changes in the temperature field of the plate is determined. The obtained results were compared with the data of other authors and can be used when taking into account the thermal shock of large elastic elements of spacecraft.
本文致力于在ANSYS软件包中模拟热冲击对薄板的影响。对板的应力应变状态进行了评估,确定了板的温度场的动态变化。所得结果与其他作者的数据进行了比较,可用于考虑航天器大弹性元件的热冲击。
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引用次数: 0
Design and simulation of AI remote terminal user identity recognition system based on reinforcement learning 基于强化学习的AI远程终端用户身份识别系统设计与仿真
Pub Date : 2021-11-29 DOI: 10.1142/s1793962323410052
Yan Chen
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引用次数: 1
New compounding lifetime distributions with applications to real data 新的复合生命周期分布,应用于实际数据
Pub Date : 2021-11-29 DOI: 10.1142/s1793962322500386
Leila Esmaeili, M. Niaparast
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引用次数: 0
A novel user review-based contextual recommender system 一种基于用户评论的上下文推荐系统
Pub Date : 2021-11-24 DOI: 10.1142/s1793962323410027
N. Khan, R. Mahalakshmi
Recommendation systems are shrewd applications for knowledge mining that profoundly handle the problem of data overload. Various literature explores different philosophies to create ideas and recommends different strategies according to the needs of customers. Most of the work in the suggested structure space focuses on extending the accuracy of the recommendation by using a few possible methods where the principle purpose remains to improve the accuracy of suggestions while avoiding other plan objectives, such as the particular situation of a client. By using appropriate customer rating data, the biggest test for a suggested system is to generate substantial proposals. A setting is an enormous concept that can think of numerous points of view: for example, the community of friends of a client, time, mindset, environment, organization, type of day, classification of an item, description of the object, place, and language. The rating behavior of customers typically varies in different environments. We have proposed a new review-based contextual recommender (RBCR) system application from this line of analysis, in particular a novel recommender system, which is an adaptable, quick, and accurate piece planning framework that perceives the significance of setting and fuses the logical data using piece stunt while making expectations. We have contrasted our suggested calculation with pre- and post-sifting methods as they have been the most common methodologies in writing to illuminate the issue of setting conscious suggestion. Our studies show that considering the logical data, the display of a system will increase and provide better, appropriate and important results on various evaluation measurements.
推荐系统是知识挖掘的精明应用,它深刻地处理了数据过载问题。各种文献探索不同的哲学来创造想法,并根据客户的需求推荐不同的策略。建议结构空间中的大部分工作都侧重于通过使用一些可能的方法来扩展推荐的准确性,这些方法的主要目的仍然是提高建议的准确性,同时避免其他计划目标,例如客户的特定情况。通过使用适当的客户评级数据,对建议系统的最大测试是生成实质性的建议。背景是一个巨大的概念,可以考虑许多观点:例如,客户的朋友社区,时间,心态,环境,组织,一天的类型,物品的分类,物体的描述,地点和语言。顾客的评级行为在不同的环境中通常是不同的。基于这一思路,我们提出了一种新的基于评论的上下文推荐(RBCR)系统应用,特别是一种新颖的推荐系统,它是一种适应性强、快速准确的片段规划框架,能够感知场景的重要性,并在做出期望的同时使用片段特技融合逻辑数据。我们将我们建议的计算与筛选前和筛选后的方法进行了对比,因为它们是书面中最常见的方法,以阐明设置有意识建议的问题。我们的研究表明,考虑到逻辑数据,系统的显示将会增加,并在各种评估测量中提供更好、合适和重要的结果。
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引用次数: 0
Modeling and simulation of the "IL-36 cytokine" and CAR-T cells interplay in cancer onset 模拟和模拟“IL-36细胞因子”和CAR-T细胞在癌症发病中的相互作用
Pub Date : 2021-11-13 DOI: 10.1142/s1793962322500209
K. Al-Utaibi, Alessandro Nutini, A. Sohail, Robia Arif, Sümeyye Tunç, S. M. Sait
Background: CAR-T cells are chimeric antigen receptor (CAR)-T cells; they are target-specific engineered cells on tumor cells and produce T cell-mediated antitumor responses. CAR-T cell therapy is the “first-line” therapy in immunotherapy for the treatment of highly clonal neoplasms such as lymphoma and leukemia. This adoptive therapy is currently being studied and tested even in the case of solid tumors such as osteosarcoma since, precisely for this type of tumor, the use of immune checkpoint inhibitors remained disappointing. Although CAR-T is a promising therapeutic technique, there are therapeutic limits linked to the persistence of these cells and to the tumor’s immune escape. CAR-T cell engineering techniques are allowed to express interleukin IL-36, and seem to be much more efficient in antitumoral action. IL-36 is involved in the long-term antitumor action, allowing CAR-T cells to be more efficient in their antitumor action due to a “cross-talk” action between the “IL-36/dendritic cells” axis and the adaptive immunity. Methods: This analysis makes the model useful for evaluating cell dynamics in the case of tumor relapses or specific understanding of the action of CAR-T cells in certain types of tumor. The model proposed here seeks to quantify the action and interaction between the three fundamental elements of this antitumor activity induced by this type of adoptive immunotherapy: IL-36, “armored” CAR-T cells (i.e., engineered to produce IL-36) and the tumor cell population, focusing exclusively on the action of this interleukin and on the antitumor consequences of the so modified CAR-T cells. Mathematical model was developed and numerical simulations were carried out during this research. The development of the model with stability analysis by conditions of Routh–Hurwitz shows how IL-36 makes CAR-T cells more efficient and persistent over time and more effective in the antitumoral treatment, making therapy more effective against the “solid tumor”. Findings: Primary malignant bone tumors are quite rare (about 3% of all tumors) and the vast majority consist of osteosarcomas and Ewing’s sarcoma and, approximately, the 20% of patients undergo metastasis situations that is the most likely cause of death. Interpretation: In bone tumor like osteosarcoma, there is a variation of the cellular mechanical characteristics that can influence the efficacy of chemotherapy and increase the metastatic capacity; an approach related to adoptive immunotherapy with CAR-T cells may be a possible solution because this type of therapy is not influenced by the biomechanics of cancer cells which show peculiar characteristics.
背景:CAR-T细胞是嵌合抗原受体(CAR)-T细胞;它们是肿瘤细胞上的靶向特异性工程细胞,并产生T细胞介导的抗肿瘤反应。CAR-T细胞疗法是免疫疗法治疗淋巴瘤和白血病等高度克隆性肿瘤的“一线”疗法。这种过继疗法目前正在研究和测试,甚至在实体肿瘤如骨肉瘤的情况下,因为正是对于这类肿瘤,免疫检查点抑制剂的使用仍然令人失望。尽管CAR-T是一种很有前途的治疗技术,但这些细胞的持久性和肿瘤的免疫逃逸都存在治疗限制。CAR-T细胞工程技术被允许表达白细胞介素IL-36,并且似乎在抗肿瘤作用中更有效。IL-36参与了长期的抗肿瘤作用,由于“IL-36/树突状细胞”轴与适应性免疫之间的“串话”作用,使得CAR-T细胞的抗肿瘤作用更有效。方法:这一分析使得该模型有助于在肿瘤复发的情况下评估细胞动力学或具体了解CAR-T细胞在某些类型肿瘤中的作用。本文提出的模型旨在量化这种过继免疫疗法诱导的抗肿瘤活性的三个基本要素之间的作用和相互作用:IL-36,“装甲”CAR-T细胞(即,设计以产生IL-36)和肿瘤细胞群,专注于这种白细胞介素的作用和如此修饰的CAR-T细胞的抗肿瘤后果。在研究过程中建立了数学模型并进行了数值模拟。通过Routh-Hurwitz条件下的稳定性分析,该模型的发展显示了IL-36如何使CAR-T细胞随着时间的推移更有效和持久,在抗肿瘤治疗中更有效,使治疗对“实体瘤”更有效。结果:原发性恶性骨肿瘤非常罕见(约占所有肿瘤的3%),绝大多数由骨肉瘤和尤文氏肉瘤组成,大约20%的患者发生转移,这是最可能导致死亡的原因。解释:在骨肿瘤如骨肉瘤中,存在细胞力学特性的变化,可影响化疗的疗效并增加转移能力;一种与CAR-T细胞过继免疫治疗相关的方法可能是一种解决方案,因为这种类型的治疗不受癌细胞生物力学的影响,而癌细胞表现出特殊的特征。
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引用次数: 0
Reducing catastrophic forgetting problem in streaming data by Hybrid Shark Smell with Jaya Optimization-based Deep Neural Networks 基于Jaya优化的深度神经网络混合鲨鱼气味减少流数据中的灾难性遗忘问题
Pub Date : 2021-11-01 DOI: 10.1142/s1793962322500301
Maisnam Niranjan Singh, Samitha Khaiyum
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引用次数: 0
Knowledge-based systems for blockchain-based cognitive cloud computing model for security purposes 基于区块链的安全认知云计算模型的基于知识的系统
Pub Date : 2021-10-27 DOI: 10.1142/s1793962322410021
Honglei Zhang, Zhenbo Zang, BalaAnand Muthu
Today, artificial intelligence (AI) can use the most powerful edge computing systems in the Internet of Things (IoT) for finding the information extracted from vast sensory data such as cyber effects or models in physical environments for classification, identification, and prediction. Heterogeneous IoT devices produce isolated and dispersed information parts, and knowledge sharing and exchange in IoT intelligent applications with several selfish nodes are necessary for complex tasks. In both academia and business, IoT is driving a digital revolution. However, protection and IoT privacy problems are challenged. It offers comfort for everyday lives. Blockchain, a shared cryptographic database, is a promising IoT encryption solution for several manufacturing, finance, and trade sectors. The IoT-based blockchain architecture is an interesting contrast to the conventional, centralized paradigm that struggles to fulfill specific IoT requirements. New concepts for applying data and resources management protection procedures in distributed networks and cloud computing are introduced. Cloud management services can be linked to the application through blockchain technology and distributed leader, a stable cognitive information system that facilitates management operations and securing data. This document provides many ideas for applying personal and behavioral characteristics to security and cryptography protocols, blockchain based on the cognitive cloud computing (BC-CCC) pattern. The simulation result shows that the proposed strategy can significantly enhance data transmission rate (96.2%), security ratio (94.5%), throughput ratio (92.4%), scalability ratio (91.5%), trust rate (93.8%), data trading ratio (96.2%), and reduce storage cost rate (25.1%) compared to other existing methods.
如今,人工智能(AI)可以利用物联网(IoT)中最强大的边缘计算系统,从海量感官数据(如物理环境中的网络效应或模型)中提取信息,进行分类、识别和预测。异构物联网设备产生孤立、分散的信息部分,具有多个自私节点的物联网智能应用中的知识共享和交换是复杂任务的必要条件。在学术界和商界,物联网正在推动一场数字革命。然而,保护和物联网隐私问题受到挑战。它为日常生活提供了舒适。区块链是一种共享的加密数据库,是一种很有前途的物联网加密解决方案,适用于多个制造业、金融和贸易部门。基于物联网的区块链架构与传统的中心化范式形成了有趣的对比,后者难以满足特定的物联网需求。介绍了在分布式网络和云计算中应用数据和资源管理保护程序的新概念。云管理服务可以通过区块链技术和分布式领导者连接到应用程序,这是一个稳定的认知信息系统,方便管理操作,保护数据。本文档为将个人和行为特征应用于安全和加密协议、基于认知云计算(BC-CCC)模式的区块链提供了许多想法。仿真结果表明,与现有方法相比,该策略可显著提高数据传输率(96.2%)、安全性(94.5%)、吞吐率(92.4%)、可扩展性(91.5%)、信任率(93.8%)、数据交易率(96.2%),降低存储成本(25.1%)。
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引用次数: 5
Artificial intelligence to link environmental endocrine disruptors (EEDs) with bone diseases 人工智能将环境内分泌干扰物(eed)与骨骼疾病联系起来
Pub Date : 2021-10-27 DOI: 10.1142/s1793962322500192
K. Al-Utaibi, M. Idrees, A. Sohail, Fatima Arif, Alessandro Nutini, S. M. Sait
Our endocrine system is not only complex, but is also enormously sensitive to the imbalances caused by the environmental stressors, extreme weather situation, and other geographical factors. The endocrine disruptions are associated with the bone diseases. Osteoporosis is a bone disorder that occurs when bone mineral density and bone mass decrease. It affects women and men of all races and ethnic groups, causing bone weakness and the risk of fractures. Environmental stresses are referred to physical, chemical, and biological factors that can impact species productivity. This research aims to examine the impact of environmental stresses on bone diseases like osteoporosis and low bone mass (LBM) in the United States (US). For this purpose, we use an artificial neural network model to evaluate the correlation between the data. A multilayer neural network model is constructed using the Levenberg–Marquardt training algorithm, and its performance is evaluated by mean absolute error and coefficient of correlation. The data of osteoporosis and LBM cases in the US are divided into three groups, including gender group, age group, and race/ethnicity group. Each group shows a positive correlation with environmental stresses and thus the endocrinology.
我们的内分泌系统不仅复杂,而且对环境压力、极端天气情况和其他地理因素造成的失衡非常敏感。内分泌紊乱与骨病有关。骨质疏松症是一种骨骼疾病,发生在骨密度和骨量减少的时候。它影响所有种族和民族的女性和男性,导致骨骼虚弱和骨折的风险。环境压力是指能够影响物种生产力的物理、化学和生物因素。本研究旨在研究环境压力对美国骨质疏松症和低骨量(LBM)等骨病的影响。为此,我们使用人工神经网络模型来评估数据之间的相关性。采用Levenberg-Marquardt训练算法构建多层神经网络模型,并通过平均绝对误差和相关系数对其性能进行评价。美国的骨质疏松症和LBM病例数据分为三组,包括性别组、年龄组和种族/民族组。每一组都显示出与环境压力和内分泌学呈正相关。
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引用次数: 7
A stochastic SIR model for analysis of testosterone suppression of CRH-stimulated cortisol in men 一个随机SIR模型用于分析男性crh刺激的皮质醇的睾酮抑制
Pub Date : 2021-10-23 DOI: 10.1142/s1793962322500210
Adhiyaman Manickam, Pushpendra Kumar, K. Dasunaidu, Govindaraj Venkatesan, D. Joshi
A stochastic SIR influenza vertical transmission model is examined in this paper where vaccination and an incidence rate that is not linear are considered. To determine whether testosterone regulates lower sintering HPA axis function in males, we used a stochastic SIR epidemic procedure with divergent influences on ACTH and cortisol. The suppressive effects on cortisol can be attributed to a peripheral (adrenal) locus. Following that, we came to the conclusion that experimental solutions have been discovered and the requisite statistical findings have been examined. Finally, we deduce that the given mathematical model and the results are relevant to medical research. In the future, this research can be further extended to simulate more results in the medical field.
本文研究了随机SIR流感垂直传播模型,其中考虑了疫苗接种和非线性发病率。为了确定睾酮是否调节男性低烧结HPA轴功能,我们使用了随机SIR流行病程序,对ACTH和皮质醇的影响不同。对皮质醇的抑制作用可归因于外周(肾上腺)位点。在此之后,我们得出的结论是,已经找到了实验解决方案,并检查了必要的统计结果。最后,我们推断出给定的数学模型和结果与医学研究有关。在未来,本研究可以进一步扩展,在医学领域模拟更多的结果。
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引用次数: 2
Study and analysis of various sentiment classification strategies: A challenging overview 各种情绪分类策略的研究和分析:一个具有挑战性的概述
Pub Date : 2021-10-20 DOI: 10.1142/s1793962322500015
Mandar Kundan Keakde, A. Muddana
In large-scale social media, sentiment classification is a significant one for connecting gaps among social media contents as well as real-world actions, including public emotional status monitoring, political election prediction, and so on. On the other hand, textual sentiment classification is well studied by various platforms, like Instagram, Twitter, etc. Sentiment classification has many advantages in various fields, like opinion polls, education, and e-commerce. Sentiment classification is an interesting and progressing research area due to its applications in several areas. The information is collected from various people about social, products, and social events by web in sentiment analysis. This review provides a detailed survey of 50 research papers presenting sentiment classification schemes such as active learning-based approach, aspect learning-based method, and machine learning-based approach. The analysis is presented based on the categorization of sentiment classification schemes, the dataset used, software tools utilized, published year, and the performance metrics. Finally, the issues of existing methods considering conventional sentiment classification strategies are elaborated to obtain improved contribution in devising significant sentiment classification strategies. Moreover, the probable future research directions in attaining efficient sentiment classification are provided.
在大型社交媒体中,情绪分类是连接社交媒体内容与现实世界行为之间差距的重要分类,包括公众情绪状态监测、政治选举预测等。另一方面,各种平台对文本情感分类进行了很好的研究,比如Instagram、Twitter等。情感分类在民意调查、教育、电子商务等各个领域都有很多优势。由于情感分类在多个领域的应用,它是一个有趣且不断发展的研究领域。通过网络情感分析,从不同的人那里收集有关社会、产品和社会事件的信息。这篇综述提供了50篇研究论文的详细调查,这些论文提出了基于主动学习的方法、基于方面学习的方法和基于机器学习的方法等情感分类方案。该分析基于情绪分类方案的分类、使用的数据集、使用的软件工具、发布年份和性能指标。最后,阐述了现有方法在考虑传统情感分类策略时存在的问题,为设计显著情感分类策略做出了更大的贡献。最后,提出了实现高效情感分类的可能的未来研究方向。
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引用次数: 1
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Int. J. Model. Simul. Sci. Comput.
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