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Bulbar urethral stricture: penile skin flap may be a good option? 球尿道狭窄:阴茎皮瓣可能是一个好选择?
L. Favorito
The September-October 2019 issue of the International Brazilian Journal of Urology presents original contributions with a lot of interesting papers in different fields: Infertility, Bladder Cancer, Prostate Cancer, Renal Cell Carcinoma, Partial nephrectomy, Kidney stones, Nocturnal Enuresis, Basic Research, Urinary Incontinence, Transplantation, UPJ Obstruction, Pelvic Organ Prolapse, Hypogonadism, Vasectomy, Herbal Medicine in Fertility and Urethral Strictures. The papers come from many different countries such as Italy, Brazil, USA, Turkey, China, France, Iran, Lebanon, Singapore, Colombia, Tunisia, India and Spain, and as usual the editor ́s comment highlights some papers. We decided to comment the paper about a very interesting topic: Penile skin flap for anterior urethral sctricture (1). Doctor Hmida and collegues from the Sahloul Hospital Sousse, Tunisia, performed on page 1057 an interesting study about the Penile skin flap for anterior urethral stricture. They studied 77 patients underwent substitution urethroplasty using dorsal penile skin flap for bulbar urethral strictures. The mean stricture length was 5cm (3-10 cm) and the mean flap length was 6cm. The mean follow-up was 60 months (6-120). The overall success rate was 88%. The authors concluded that urethroplasty using penile skin flap appear to be a safe and efficient technique for the treatment of a long and complex anterior urethral stricture. There are several options for the treatment of anterior urethral stricture (2-4). The patient’s stricture position, length and complexity are important factors to decide the surgical technique (5-7). For long bulbar strictures the buccal mucosa graft (BMG) as gold-standard material due to its histological characteristics and very good long term results (8-12). However, there are multiple situations whereby BMG is inadequate (prior buccal harvest) or inappropriate for utilization (heavy oral radiation). The fascio-cutaneous flaps could be a good option in these situations. The penile skin flap is easy to perform, do not need urethral mobilization and the present paper shows a success rate of 88%, a very significant number. We congratulate the authors for this very important contribution.
2019年9 - 10月的《国际巴西泌尿外科杂志》发表了许多不同领域的原创论文:不孕症、膀胱癌、前列腺癌、肾细胞癌、部分肾切除术、肾结石、夜间遗尿、基础研究、尿失禁、移植、UPJ阻塞、盆腔器官脱垂、性腺功能减退、输精管切除术、生育和尿道狭窄的草药。这些论文来自许多不同的国家,如意大利、巴西、美国、土耳其、中国、法国、伊朗、黎巴嫩、新加坡、哥伦比亚、突尼斯、印度和西班牙,和往常一样,编辑的评论突出了一些论文。我们决定评论这篇文章关于一个非常有趣的话题:阴茎皮瓣治疗前尿道狭窄(1)。来自突尼斯Sousse Sahloul医院的Hmida医生和他的同事在1057页上做了一项关于阴茎皮瓣治疗前尿道狭窄的有趣研究。他们研究了77例采用阴茎背侧皮瓣替代尿道成形术治疗球尿道狭窄的患者。狭窄长度平均为5cm (3 ~ 10cm),皮瓣长度平均为6cm。平均随访60个月(6-120)。总成功率为88%。作者认为阴茎皮瓣尿道成形术是治疗长而复杂的前尿道狭窄的一种安全有效的方法。治疗前尿道狭窄有几种选择(2-4)。患者的狭窄位置、长度和复杂性是决定手术技术的重要因素(5-7)。对于长球狭窄,颊黏膜移植物(BMG)由于其组织学特征和非常好的长期效果而成为金标准材料(8-12)。然而,在许多情况下,BMG是不充分的(事先口腔收获)或不适合使用(重度口腔辐射)。在这种情况下,筋膜皮瓣可能是一个很好的选择。阴茎皮瓣操作简单,不需要动员尿道,成功率为88%,是一个非常显著的数字。我们祝贺作者的这一非常重要的贡献。
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引用次数: 1
Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats 蒺藜和除虫菊对雄性大鼠生育参数的改善
D. Haghmorad, M. Mahmoudi, P. Haghighi, Paria Alidadiani, Ensieh Shahvazian, Parsova Tavasolian, M. Hosseini, M. Mahmoudi
ABSTRACT Objective Anacyclus Pyrethrum (AP) and Tribulus Terrestris (TT) have been reported as male infertility treatment in several studies; however, in Iranian traditional medicine these two plants are prescribed simultaneously. In this study, we aimed to determine the effects of AP and TT extracts both separately and simultaneously on the male Wistar rat fertility parameters. Materials and Methods 32 male Wistar rats were divided into 4 groups: Control, TT, AP, and AT treated groups. Treatment continued for 25 days and rats were weighed daily. Their testes were dissected for histological studies. Sperm analysis including sperm count, viability and motility were performed. Serum was obtained to evaluate testosterone, LH and FSH levels. Histological studies were conducted to study Leydig, and Sertoli cells, spermatogonia and spermatid cell numbers, and to measure seminiferous diameter and epithelium thickness. Results Sperm count increased in all the treatment groups. Sperm viability and motility in AT and AP groups were elevated. TT and AT groups showed significantly increased testosterone level compared to control group (P=004, P=0.000, respectively) and TT, AP and AT treatment groups showed increased LH level (P=0.002, P=0.03 and P=0.000, respectively) compared to control, while only AT group showed increased FSH (p=0.006) compared to control. Histological studies showed significant increase of spermatogonia, Leydig and Sertoli cell numbers and epithelial thickness in AT group compared to other groups. All the treatment groups had higher number of Leydig, spermatogonia and spermatid cells. Conclusion TT and AP improved sexual parameters; however, their simultaneous administration had higher improving effects on studied parameters.
【摘要】目的拟除虫菊(AP)和蒺藜(TT)作为治疗男性不育症的药物已有研究报道;然而,在伊朗传统医学中,这两种植物是同时开处方的。在本研究中,我们旨在确定AP和TT提取物分别和同时对雄性Wistar大鼠生育参数的影响。材料与方法雄性Wistar大鼠32只,随机分为4组:对照组、TT组、AP组、AT组。治疗持续25天,每天称重。解剖他们的睾丸进行组织学研究。进行精子分析,包括精子数量、生存力和活力。取血清测定睾酮、黄体生成素和卵泡刺激素水平。组织学研究了间质细胞、支持细胞、精原细胞和精母细胞的数量,并测量了精管直径和上皮厚度。结果各治疗组精子数量均有所增加。AT组和AP组精子活力和活力均升高。TT和AT组睾酮水平较对照组显著升高(P=004, P=0.000), TT、AP和AT治疗组LH水平较对照组显著升高(P=0.002, P=0.03, P=0.000),而只有AT组FSH水平较对照组升高(P= 0.006)。组织学研究显示,AT组精原细胞、间质细胞和支持细胞数量及上皮细胞厚度均显著高于其他各组。各处理组间质细胞、精原细胞和精母细胞数量均较高。结论TT和AP可改善性指标;但同时给药对研究参数有较高的改善作用。
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引用次数: 21
Association between calcitonin receptor gene polymorphisms and calcium stone urolithiasis: A meta-analysis 降钙素受体基因多态性与钙石尿石症之间的关系:一项荟萃分析
J. Xing, Jia-xuan Qin, Zonglong Cai, B. Duan, Peide Bai
ABSTRACT Purpose It has been reported that calcitonin receptor (CALCR) gene polymorphisms might be associated with calcium stone urolithiasis. Owing to mixed and inconclusive results, we conducted a meta-analysis to summarize and clarify this association. Materials and Methods A systematic search of studies on the association between CALCR gene polymorphisms and calcium stone urolithiasis susceptibility was conducted in databases. Results Odds ratios and 95% confidence intervals were used to pool the effect size. Five articles were included in our meta-analysis. Conclusions CALCR rs1801197 might be associated with increased risk of calcium stone urolithiasis. There is insufficient data to fully confirm the association between CALCR rs1042138 and calcium stone urolithiasis susceptibility. Well-designed studies with larger sample size and more subgroups are required to validate the risk identified in the current meta-analysis.
【摘要】目的有报道称,降钙素受体(CALCR)基因多态性可能与钙石性尿石症有关。由于混合和不确定的结果,我们进行了荟萃分析来总结和澄清这种关联。材料与方法系统检索数据库中有关CALCR基因多态性与钙石尿石症易感性关系的研究。结果优势比和95%置信区间用于汇总效应大小。我们的荟萃分析纳入了五篇文章。结论CALCR rs1801197可能与钙石性尿石症风险增加有关。目前还没有足够的数据充分证实CALCR rs1042138与钙石尿石易感性之间的关联。需要设计良好、样本量更大、亚组更多的研究来验证当前荟萃分析中确定的风险。
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引用次数: 4
Focal therapy for prostate cancer – index lesion treatment vs. hemiablation. A matter of definition 前列腺癌的局灶治疗-指数病变治疗与半消融术。定义的问题
A. Stabile, M. Moschini, F. Montorsi, X. Cathelineau, R. Sanchez-Salas
1 Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy; 2 Klinik für Urologie, Luzerner Kantonsspital, Lucerne, Switzerland; 3 Department of Urology, Institut Mutualiste Montsouris and Université Paris Descartes, Paris, France Vol. 45 (5): 873-876, September October, 2019
1意大利圣拉斐尔大学泌尿研究所泌尿外科及实验肿瘤科,意大利米兰;2瑞士卢塞恩Klinik 泌尿外科医院,卢塞恩;3巴黎笛卡尔大学泌尿外科,蒙特苏里互惠研究所,巴黎,Vol. 45(5): 873-876, 2019年9月- 10月
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引用次数: 11
Macroplastique for women with stress urinary incontinence secondary to intrinsic sphincter deficiency 大塑形术治疗女性压力性尿失禁继发于内在括约肌缺陷
Timothy F. Carroll, A. Christie, M. Foreman, G. Khatri, P. Zimmern
ABSTRACT Objective To evaluate the subjective and objective outcomes of Macroplastique® (MPQ) in women with stress urinary incontinence (SUI) secondary to intrinsic sphincter deficiency (ISD). Materials and Methods Following Institutional Review Board (IRB) approval, charts of non-neurogenic women with SUI secondary to ISD who underwent MPQ injection and had 6 months minimum follow-up were reviewed from a prospectively maintained database. Patients were divided into 3 groups: Naïve (Group I), Prior Anti-Incontinence Surgery (Group II), and combined Prior Bulking Agent and Anti-Incontinence Surgery (Group III). Data collected included SUI self-report, Urogenital Distress Inventory (UDI-6) Question 3, and VAS Quality of Life (QoL) Questionnaire scores at baseline and in follow-up. Three-dimensional ultrasound (3DUS) evaluated volume/configuration of MPQ. Success was defined after the last MPQ injection as a UDI-6 Question 3 score of 0 (dry) or 1, and no reoperation for SUI. Results From 2011-2017, 106 of 142 women met study criteria. At a median follow-up of 20 months (mean=26 months; range: 6-71), success rate was 41% for Group I, 40% for Group II, and 65% for Group III (p = 0.22). QoL scores were significantly improved over baseline in all groups. There was no significant difference in clinical outcome between the asymmetrical and symmetrical group on 3DUS. The completely dry rate was highest in Group III at 29%, compared to 4% for Group I and 15% for Group II (p = 0.05). Conclusion Macroplastique® improved subjective and objective outcome measures for SUI secondary to ISD as both a primary and secondary treatment option in women.
【摘要】目的评价Macroplastique®(MPQ)治疗女性压力性尿失禁(SUI)继发于内生性括约肌缺陷(ISD)的主客观预后。材料和方法经机构审查委员会(IRB)批准,从前瞻性维护的数据库中回顾了接受MPQ注射并进行至少6个月随访的非神经源性SUI继发于ISD的女性患者的图表。患者分为Naïve组(第一组)、既往抗失禁手术(第二组)、既往膨化剂联合抗失禁手术(第三组)。收集的数据包括SUI自我报告、泌尿生殖窘迫量表(UDI-6)问题3、基线和随访时VAS生活质量问卷得分。三维超声(3DUS)评估MPQ的体积/构型。最后一次MPQ注入后,UDI-6问题3评分为0(干)或1,并且没有SUI再次手术。结果2011-2017年,142名女性中有106名符合研究标准。中位随访20个月(平均26个月;范围:6-71),第一组的成功率为41%,第二组为40%,第三组为65% (p = 0.22)。所有组的生活质量评分均较基线有显著改善。不对称组和对称组在3DUS上的临床结果无显著差异。完全干燥率以ⅲ组最高,为29%,ⅰ组为4%,ⅱ组为15% (p = 0.05)。结论Macroplastique®作为女性ISD继发SUI的主要和次要治疗选择,改善了主观和客观结局指标。
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引用次数: 8
Editorial Comment: Portable model for vasectomy reversal training 编辑评论:输精管结扎逆转训练的便携式模型
Pub Date : 2019-01-29 DOI: 10.1590/S1677-5538.IBJU.2019.0092.1
R. Vieiralves
We know that microsurgery training is still far from becoming a reality during the process of training residents in Brazil. In fact, there is a gap around the world and therefore, just the fact that we have an article dealing with this topic is already of great relevance. In this very interesting article conducted at Para State University, Brazil (1), a portable training model for vasectomy reversal was adopted. We know that with the current juncture of society and the number of vasectomies performed worldwide, there is an increasing demand for vasectomy reversal mainly associated with a new post-vasectomy relationship. The paper in question becomes even more relevant because of it ́s bimodal certification for microsurgical training based on a time performance and on a check list not only measuring the execution time of vasovasostomy but also with a checklist questionnaire assessing the most diverse specific items of an perfect anastomosis (eg, if the resident is placed in a comfortable position, equidistance between knots, number of knots, continuous needle vision, etc). We understand that this bimodal evaluation increases the accuracy in the training, since the time does not necessarily correlate with the quality of the anastomosis. However, some relevant aspects need to be highlighted. Vasectomy reversal surgery involves a complex number of factors for its true success. The preparation of the surgical field itself, the section of adhesions and previous fibrosis, the calibration and approximation of the deferens ends without tension, the stabilization of the anastomosis, the patency test, the observation of the four deferent layers in the intraoperative period -mucosa, two layers of muscle and the adventitia(failure to observe two muscle layers may indicate residual vasectomy scarring). Blood supply evaluation by thin mucosal bleeding is also important (2). None of these fundamental points for surgical success is reproduced through the present model. Moreover, we know that the technique used in the model, proposed by Benlloch (3) with only 4 sutures in a single layer is not a reference in the literature. Today, we found no statistical difference in patency or pregnancy results for twoand one-layer vasovasostomy but a minimum number of 6 sutures presumably offers a high quality anastomosis by preventing sperm leakage and the associated risk of granuloma (4, 5). Some considerations regarding the materials used should be made. A technical point is the fact that using an 8-0 suture could facilitate training without simulating real anastomosis situations. We understand that further in vivo studies with thicker sutures in a single anastomotic layer are needed to validate this model (6, 7). Also, as much as the 3D printed model addresses important aspects such as the presence of two layers allowing the training of two types of anastomoses, single layer or double layer, the consistency of the material hardly simulates the vas deferens real physical pro
我们知道,在巴西培训住院医师的过程中,显微外科培训还远远没有成为现实。事实上,世界各地都存在差距,因此,我们有一篇关于这个话题的文章已经非常相关了。在巴西帕拉州立大学进行的一篇非常有趣的文章中(1),采用了一种便携式输精管结扎逆转训练模型。我们知道,随着当前社会的发展和世界范围内输精管切除术的数量,输精管切除术逆转的需求越来越大,主要与输精管切除术后的新关系有关。这篇论文变得更加相关,因为它基于时间表现和检查表对显微外科培训进行了双式认证,不仅测量了血管输精管吻合术的执行时间,而且还使用检查表问卷评估了完美吻合的最多样化的具体项目(例如,如果住院医师被放置在一个舒适的位置,结之间的等距离,结的数量,连续的针视力等)。我们知道,这种双峰评估增加了训练的准确性,因为时间不一定与吻合的质量相关。然而,需要强调一些相关方面。输精管结扎逆转手术的真正成功涉及复杂的因素。手术野本身的准备,粘连和既往纤维化的切片,输精管末端无张力的校准和近似,吻合口的稳定,通畅试验,术中观察四层不同的层-粘膜,两层肌肉和外膜(未能观察两层肌肉可能表明输精管结扎残余疤痕)。通过薄粘膜出血评估血供也很重要(2)。本模型没有重现手术成功的这些基本点。此外,我们知道模型中使用的技术,由Benlloch(3)提出,在单层中只有4个缝合线,在文献中没有引用。目前,我们发现两层和一层输精管造口术在通畅性和妊娠结果上没有统计学差异,但至少6条缝合线可能通过防止精子漏出和相关肉芽肿风险提供高质量的吻合(4,5)。在使用材料时应考虑一些因素。一个技术要点是,使用8-0缝线可以方便训练,而无需模拟真实的吻合情况。我们知道,需要在单个吻合层中使用更厚的缝合线进行进一步的体内研究来验证该模型(6,7)。此外,尽管3D打印模型解决了一些重要问题,例如两层的存在,允许训练两种类型的吻合层,单层或双层,但材料的一致性很难模拟输精管的真实物理特性。因为外部PVA涂层可能提供比真正的更高的电阻。另一点是,没有关于如何将模型固定在训练表上的精确描述,因为任何动员都会使所有训练变得困难和不准确。在使用显微镜时使用的放大倍率也没有被描述。社评45卷(5):1020-1021,2019年9月-10月
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引用次数: 0
Brazilian consensus in enuresis–recomendations for clinical practice 巴西关于遗尿的共识——临床实践建议
J. M. Netto, A. Rondon, G. D. de Lima, Miguel Zerati, E. D. Schneider-Monteiro, C. A. Molina, A. Calado, U. Barroso
ABSTRACT Introduction Enuresis, defined as an intermittent urinary incontinence that occurs during sleep, is a frequent condition, occurring in about 10% of children at 7 years of age. However, it is frequently neglected by the family and by the primary care provider, leaving many of those children without treatment. Despite of many studies in Enuresis and recent advances in scientific and technological knowledge there is still considerable heterogeneity in evaluation methods and therapeutic approaches. Materials and Methods The board of Pediatric Urology of the Brazilian Society of Urology joined a group of experts and reviewed all important issues on Enuresis and elaborated a draft of the document. On September 2018 the panel met to review, discuss and write a consensus document. Results and Discussion Enuresis is a multifactorial disease that can lead to a diversity of problems for the child and family. Children presenting with Enuresis require careful evaluation and treatment to avoid future psychological and behavioral problems. The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies.
遗尿症,定义为睡眠中发生的间歇性尿失禁,是一种常见的疾病,约10%的7岁儿童发生。然而,它经常被家庭和初级保健提供者所忽视,使许多儿童得不到治疗。尽管有许多关于遗尿症的研究和最近的科学技术知识的进步,但在评估方法和治疗方法上仍然存在相当大的异质性。材料和方法巴西泌尿外科学会儿科泌尿外科委员会与专家组一起审查了遗尿症的所有重要问题,并详细制定了文件草案。2018年9月,专家组开会审查、讨论并撰写共识文件。结果与讨论遗尿症是一种多因素疾病,可导致儿童和家庭的各种问题。患有遗尿症的儿童需要仔细的评估和治疗,以避免未来的心理和行为问题。小组讨论了最新诊断、评估和治疗选择的建议。
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引用次数: 10
REPLY BY THE AUTHORS: Re: Antibiotic prophylaxis prior to urodynamic study in patients with traumatic spinal cord injury. Is there an indication? 作者回复:回复:外伤性脊髓损伤患者尿动力学研究前抗生素预防。有什么迹象吗?
Pub Date : 2019-01-08 DOI: 10.1590/S1677-5538.IBJU.2018.0193.1
M. R. D. Silva, A. L. Barboza, M. Pijoán, P. Beraldo
We thank you for your comments on our latest publication (1). Indeed, what has motivated us the most to carry out this investigation was the lack of evidence concerning the usage of antimicrobials prior to urodynamic studies in spinal cord injured patients (2). An unexpected result for us was the greater incidence of urinary tract infection upon patients with injuries at T6 or above, regardlessly of the use of antimicrobials prior to the procedure. At this exact moment we are working on a new publication that details the incidence of urinary tract infection specifi cally amongst the 379 spinal cord injured patients with injuries at T6 or above, now considering the presence of autonomic dysrefl exia and urodynamic parameters. The results are becoming clinically relevant.
我们感谢您对我们最新出版物的评论(1)。事实上,我们开展这项调查的最大动机是缺乏关于脊髓损伤患者在尿动力学研究之前使用抗菌药物的证据(2)。对我们来说,一个意想不到的结果是T6或以上损伤患者的尿路感染发生率更高,无论在手术之前使用抗菌药物。此时此刻,我们正在撰写一份新的出版物,详细介绍了379名T6或以上损伤的脊髓损伤患者的尿路感染发生率,现在考虑到自主神经反射异常和尿动力学参数的存在。这些结果正变得具有临床意义。
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引用次数: 0
Int Braz J Urol Annual Report - 2017 2017年巴西J rol年度报告
S. Glina
Traditionally, every year, the International Brazilian Journal of Urology evaluates its reviewers and selects the most efficient along the previous year, Evaluation is based on the number of performed reviews, time for conclusion and quality of work (1). In 2017, the five most efficient reviewers were: Fabio Vicentini (Hospital das Clínicas da Faculdade de Medicina da USP, SP, Brasil), Eduardo Kaiser Ururahy Nunes Fonseca (Hospital Israelita Albert Einstein SP, Brasil), Victor Srougi (Faculdade de Medicina de São Paulo, SP, Brasil), Elcio Silva (Clínica Dr. Élcio Dias Silva, Campinas, SP, Brasil) and Kemal Sarica (Kartal Dr. Lufi Kirdar Training and Research Hospital Istanbul, Turkey). We would like to thank them and all others reviewers, that are the reason for the existence of a peer-review scientific journal. Int Braz J Urol is an open-access magazine, integrally supported by the Brazilian Urological Society, that does not charge for the submission of papers. Also, it is included in the Urology Green List (2), that reunites all reliable and safe urological journals on which the urological community can publish their researches. In 2017, our Journal received 603 papers, and 28% were accepted. Medium time for first decision correspondence was 44 days, and more 42 days for publishing as Ahead of Print. Papers were sent from 42 countries, from 635 different institutions and 2254 authors; we used 1135 reviewers. The 5-year impact factor of IBJU in 2017 was 1.097.
传统上,国际巴西泌尿外科杂志每年都会对其审稿人进行评估,并选择上一年效率最高的审稿人,评估基于执行审稿数量,结论时间和工作质量(1)。2017年,五位效率最高的审稿人分别是:法比奥·维森蒂尼(巴西国立医院Clínicas)、爱德华多·凯撒·乌鲁拉希·努内斯·丰塞卡(巴西以色列阿尔伯特·爱因斯坦医院SP)、维克多·斯鲁吉(巴西圣保罗医学院SP)、埃尔西奥·席尔瓦(Clínica Élcio迪亚斯·席尔瓦博士,巴西坎皮纳斯SP)和凯末尔·萨里卡(土耳其伊斯坦布尔卢菲·基尔达尔博士培训和研究医院)。我们要感谢他们和所有其他审稿人,他们是同行评议科学期刊存在的原因。《Int Braz J Urol》是一本开放获取的杂志,由巴西泌尿学会(Brazilian urology Society)提供全面支持,不收取论文投稿费用。此外,它还被列入泌尿外科绿色列表(2),该列表将所有可靠和安全的泌尿外科期刊联合起来,泌尿外科社区可以在这些期刊上发表他们的研究。2017年本刊共接收论文603篇,被录用28%。第一次决策通信的中间时间是44天,提前出版则需要42天。论文来自42个国家,635个不同的机构和2254位作者;我们使用了1135名评论者。2017年IBJU的5年影响因子为1.097。
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引用次数: 0
Full-thickness skin mesh graft vaginoplasty: a skin sparing technique 全层皮肤网片阴道成形术:一种保皮技术
G. Motta, P. Tavares, G. V. D. da Silva, Milton Berger, B. Silva, T. Rosito
ABSTRACT Introduction: The ideal vaginoplasty method should promote good cosmetic and functional results with low morbidity. We describe a new technique for congenital vaginal agenesis using a full-thickness perforated skin graft. Materials and Methods: We report an 18 year old patient with vaginal agenesis (Morris syndrome) that undergone a modified version of McIndoe vaginoplasty. Patient is set in a low lithotomy position and lateral traction sutures are placed in labia and a 16Fr urethral catheter inserted. An inverted “V”-shaped incision is made in the mucosal plaque below the urethra. Blunt dissection in a cephalic posterior direction forms a space between the rectum and urethra. Special care is taken to avoid rectal tear during this maneuver. A full-thickness skin graft is removed from the lower abdomen measuring 12.0×6.0cm as an aesthetic abdominoplasty. The fat tissue is removed, remaining epidermis and dermis and the graft is perforated, allowing a great surface increase. After suturing over a mold, the graft is fixed in the created space. The donor site is closed with intradermal transversal suture. Results: From January 2009 to August 2015, seven patients diagnosed with vaginal agenesis underwent this technique. There were no major complications or need for blood transfusions. At the six-month follow-up, all patients reported satisfactory sexual intercourse. There were no significant complications at donor site or neovagina that needed surgical intervention. Conclusion: Vaginal reconstruction using the perforated graft is viable with excellent functional results. Applying this modification, we yielded the good results of a classic McIndoe technique with lower donor site morbidity.
摘要简介:理想的阴道成形术应具有良好的美观和功能效果,且发病率低。我们描述了一种新的技术先天性阴道发育不全使用全层穿孔皮肤移植。材料和方法:我们报告了一位18岁的阴道发育不全(莫里斯综合征)患者,接受了改良版的McIndoe阴道成形术。将患者置于低位取石位,在阴唇放置外侧牵引缝合线,并插入16Fr导尿管。在尿道下方的粘膜斑块上做一个倒“V”形切口。在头侧后方钝性剥离形成直肠和尿道之间的间隙。在此操作中要特别注意避免直肠撕裂。从下腹取出全层皮肤移植物,测量为12.0×6.0cm作为一种美观的腹部成形术。脂肪组织被移除,剩下的表皮和真皮和移植物被穿孔,允许很大的表面增加。在模具上缝合后,移植物被固定在创建的空间中。用皮内横向缝合闭合供体部位。结果:2009年1月至2015年8月,7例诊断为阴道发育不全的患者接受了该手术。没有重大并发症,也不需要输血。在六个月的随访中,所有患者都报告了满意的性交。供体部位和新阴道均无明显并发症需要手术干预。结论:阴道穿孔移植物重建阴道是可行的,功能效果良好。应用这种改良,我们获得了经典McIndoe技术的良好结果,供体部位发病率较低。
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引用次数: 5
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International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology
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