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Did 'long COVID' increase road deaths in the USA? 长 COVID "是否增加了美国的道路死亡率?
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045136
Leon Robertson

Objective: To examine data on COVID-19 disease associated with a 10% increase in US road deaths from 2020 to 2021 that raises the question of the potential effect of pandemic stress and neurological damage from COVID-19 disease.

Methods: Poisson regression was used to estimate the association of recent COVID-19 cases, accumulated cases, maximum temperatures, truck registrations and gasoline prices with road deaths monthly among US states in 2021. Using the regression coefficients, changes in each risk factor from 2020 to 2021 were used to calculate expected deaths in 2021 if each factor had remained the same as in 2020.

Results: Corrected for the other risk factors, road deaths were associated with accumulated COVID-19 cases but not concurrent cases. More than 20 700 road deaths were associated with the changes in accumulated COVID-19 cases but were substantially offset by about 19 100 less-than-expected deaths associated with increased gasoline prices.

Conclusions: The lingering effects of COVID-19 on neurological function may be a risk factor for behaviour leading to road deaths.

目的:研究 COVID-19 疾病与 2020 年至 2021 年美国道路死亡人数增加 10%相关的数据,该数据提出了 COVID-19 疾病可能造成的流行压力和神经损伤的问题:采用泊松回归法估算了 2021 年美国各州近期 COVID-19 病例、累积病例、最高气温、卡车注册量和汽油价格与每月公路死亡人数的关系。利用回归系数,用 2020 年至 2021 年每个风险因素的变化来计算 2021 年的预期死亡人数(如果每个因素与 2020 年相同):结果:在对其他风险因素进行校正后,公路死亡与 COVID-19 的累积病例有关,但与并发病例无关。超过 20 700 例道路死亡与 COVID-19 累计病例的变化有关,但汽油价格上涨导致的约 19 100 例低于预期的死亡大大抵消了这一变化:结论:COVID-19 对神经功能的持续影响可能是导致道路死亡的行为风险因素。
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引用次数: 0
Gun violence exposure and population health inequality: a conceptual framework. 枪支暴力暴露与人口健康不平等:一个概念框架。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045197
Daniel C Semenza, Nicole Kravitz-Wirtz

This essay establishes a conceptual framework to understand how direct, secondar and community exposures to gun violence converge to influence population health. Our framework asserts that persistent gun violence in structurally disadvantaged communities enacts broad consequences for mental, physical and behavioural health, operating as a key driver of racial and socioeconomic health disparities. We discuss the applications of this framework for research and improved data collection with a focus on establishing timely and accurate measures of gun violence alongside individual and community health measures. We then address the policy implications of the framework, emphasising the need for long-term, institutional investment in gun violence prevention and intervention, survivor service provision and evidence-based policies at all levels of government.

本文建立了一个概念框架,以了解枪支暴力的直接、间接和社区接触如何共同影响人口健康。我们的框架认为,结构上处于不利地位的社区中持续存在的枪支暴力会对精神、身体和行为健康产生广泛影响,是种族和社会经济健康差异的主要驱动因素。我们讨论了这一框架在研究和改进数据收集方面的应用,重点是建立及时、准确的枪支暴力衡量标准以及个人和社区健康衡量标准。然后,我们讨论了该框架的政策影响,强调各级政府需要对枪支暴力预防和干预、幸存者服务提供和循证政策进行长期、制度性投资。
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引用次数: 0
Cost-effectiveness of the 'Stay One Step Ahead' Home Safety programme for the prevention of injuries among children under 5 years. 先行一步 "家庭安全计划在预防 5 岁以下儿童受伤方面的成本效益。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2024-045236
Matthew Jones, Elizabeth Orton, Michael James Taylor, Clare Timblin, Rachel Clarke, Michael Craig Watson, Mike Hayes, Tina Patel, Carol Coupland, Denise Kendrick

Background: Unintentional injuries are a common cause of morbidity and mortality in the under-5s, but undertaking home safety practices can reduce injury risk. Stay One Step Ahead (SOSA) is an evidence-based standardised home safety programme. This study evaluates the cost-effectiveness of SOSA versus usual care in Nottingham, UK.

Methods: Cost-effectiveness analysis from a National Health Service and personal social services perspective. SOSA activity data, injury occurrence and associated short-term healthcare costs were collected within a controlled before-and-after study from 2017 to 2020. The primary outcome was the incremental cost-effectiveness ratio (ICER) per additional home adopting three key safety practices (working smoke alarm, safe poisons storage and fitted stair gate). Secondary outcomes were ICERs per injury avoided and quality-adjusted life-years (QALYs) gained.

Results: SOSA costs £30 per child but reduces short-term healthcare expenditure by £42. SOSA increased the number of homes with three key safety practices by 0.02 per child, reduced injuries per child by 0.15 and gained 0.0036 QALYs per child. SOSA was dominant as it was cheaper and more effective than current practice. ICERs were -£590 per additional home deemed safe, -£77 per injury avoided and -£3225 per QALY gained. Focusing on healthcare expenditure alone, SOSA saved £1.39 for every pound spent.

Conclusions: SOSA is a cost-saving intervention. Commissioners should consider implementing SOSA.

背景:意外伤害是导致 5 岁以下儿童发病和死亡的常见原因,但采取家居安全措施可以降低伤害风险。先行一步(SOSA)是一项以证据为基础的标准化家庭安全计划。本研究在英国诺丁汉评估了 SOSA 与常规护理的成本效益:方法:从国民健康服务和个人社会服务的角度进行成本效益分析。在 2017 年至 2020 年的一项前后对照研究中,收集了 SOSA 活动数据、伤害发生率和相关短期医疗成本。主要结果是每增加一户采用三种关键安全措施(正常工作的烟雾报警器、安全的毒药储存和安装楼梯门)的家庭的增量成本效益比 (ICER)。次要结果是每避免一次伤害的 ICER 和获得的质量调整生命年 (QALY):每名儿童的 SOSA 费用为 30 英镑,但可减少 42 英镑的短期医疗支出。SOSA 使采用三种关键安全措施的家庭数量每名儿童增加 0.02 个,每名儿童减少 0.15 次伤害,每名儿童获得 0.0036 QALYs。由于 SOSA 比目前的做法更便宜、更有效,因此占主导地位。每增加一个被认为安全的家庭的 ICER 为-590 英镑,每避免一次伤害为-77 英镑,每获得一个 QALY 为-3225 英镑。仅就医疗支出而言,SOSA 每花费 1 英镑就能节省 1.39 英镑:结论:SOSA 是一种节约成本的干预措施。委员们应考虑实施 SOSA。
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引用次数: 0
Non-reporting of sport-related concussion symptoms: a cross-sectional study of community rugby league players in the UK. 不报告运动相关脑震荡症状:对英国社区橄榄球联赛运动员的横断面研究。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045108
Daniel Isaac Tadmor, Lucy Chesson, Kevin Till, Gemma Phillips, Laura Fairbank, James Brown, Matt Cross, Andrew J Gardner, Rich D Johnston, Cameron Owen, Sharief Hendricks, Keith A Stokes, Ben Jones

Recognising and removing players with suspected sport-related concussions is crucial for community sports.

Objectives: Quantify rates and factors associated with non-reporting of concussion symptoms in community rugby league.

Methods: Overall, 484 community rugby league players aged ≥18 years and 965 parents of rugby league players aged <18 years completed an online survey, regarding concussion history, knowledge, prevalence and reasons for non-reporting of concussion, long-term implications and perceptions of concussion.

Results: Thirty-five percent of players aged ≥18 years and 22% of parents of players aged <18 years reported at least one concussion in the last two seasons. Forty-three percent of players aged ≥18 years and 5% of parents of players aged<18 years surveyed stated they did not report concussion-related symptoms sustained during 2020 and 2021 seasons. The two most common reasons for non-reporting of concussion symptoms were 'didn't want to be ruled out of a match' and 'didn't want to let down the team'. Players aged ≥18 years who received external coaching pressures around concussion were more likely to not report concussion symptoms. Over 40% of parents and players were concerned about the potential long-term implications. Ten percent of players aged ≥18 years and 7% of parents of players aged <18 years would encourage their family members/children to not play rugby league.

Conclusions: Non-reporting rates of suspected concussion symptoms in adult community players were twice as high as in professional rugby league, with similar reasons (wanting to play and not letting the team down). Engaging coaches to prioritise brain health and providing broader and appropriate education on concussion should be focused on, given the concerns reported by community players and parents.

对于社区体育运动而言,识别并消除疑似运动相关脑震荡的球员至关重要:量化社区橄榄球联赛中未报告脑震荡症状的比率和相关因素:方法:共调查了 484 名年龄≥18 岁的社区橄榄球联盟球员和 965 名橄榄球联盟球员的父母:35%年龄≥18岁的球员和22%年龄≥18岁的球员家长 "不想被排除在比赛之外 "和 "不想让球队失望"。年龄≥18 岁的球员如果在脑震荡方面受到外部教练的压力,则更有可能不报告脑震荡症状。超过 40% 的家长和球员对潜在的长期影响表示担忧。10%的≥18岁球员和7%的结论年龄球员的家长对脑震荡的潜在长期影响表示担忧:成年社区球员未报告疑似脑震荡症状的比例是职业橄榄球联盟的两倍,原因类似(想参加比赛和不想让球队失望)。鉴于社区球员和家长所报告的问题,应重点关注让教练员优先考虑大脑健康,并提供更广泛、更适当的脑震荡教育。
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引用次数: 0
Community and multisector partner engagement in US Vision Zero plan development. 社区和多部门合作伙伴参与美国 "零愿景 "计划的制定。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045148
Sylvia Greer, Tabitha Combs, Rebecca B Naumann, Elyse Keefe, Seth LaJeunesse, Kelly R Evenson

Background: Vision Zero aims to eliminate serious and fatal road injuries using a Safe System approach. Safe System principles establish that safety is a shared responsibility; this involves both multisector partners and community engagement. This descriptive study explored multisector partners and community engagement in the development of municipal Vision Zero plans.

Methods: We reviewed all first edition Vision Zero plans published by US municipalities from 2014 to 2022. Using a structured coding tool, we abstracted partner involvement and community engagement strategies used in the development of Vision Zero plans.

Results: We identified, reviewed and abstracted 64 plans. The average number of partner groups per plan was 11.5 (12.0 for municipalities with a population ≥150 000; 10.1 for municipalities <150 000) and was higher for later plans (11.9 for plans published 2019-2022; 10.0 for plans published 2014-2018). Common partner groups engaged in the plan were law enforcement (85.9% of plans), local transportation planning (78.3%), mayor/city council/city manager (78.1%), engineering/public works (78.1%) and schools (73.4%). Community engagement strategies were reported in 71.9% of the plans and were more frequent among municipalities with a population ≥150 000 (76.1%) compared with a population <150 000 (61.1%), and in those with more recent plans (82.1%) versus earlier ones (56.0%). The most common community engagement strategies were public meetings, online surveys and map mark-ups.

Conclusions: These findings highlight the extent to which Vision Zero plans were aligned with core Safe System tenets regarding diverse partner involvement and community engagement. Plan developers should consider the translation of Safe System principles in Vision Zero plan development.

背景:零伤亡愿景旨在采用安全系统方法消除严重和致命的道路伤害。安全系统原则规定,安全是一项共同责任;这涉及多部门合作伙伴和社区参与。这项描述性研究探讨了在制定市级 "零伤亡愿景 "计划过程中的多部门合作伙伴和社区参与情况:我们回顾了美国市政当局从 2014 年到 2022 年发布的所有第一版 "零愿景 "计划。使用结构化编码工具,我们摘录了在制定 "零愿景 "计划过程中使用的合作伙伴参与和社区参与策略:我们确定、审查并摘录了 64 项计划。每个计划的合作伙伴团体平均为 11.5 个(人口≥15 万的城市为 12.0 个;城市为 10.1 个):这些调查结果表明,"零愿景 "计划在多大程度上与 "安全系统 "关于不同合作伙伴参与和社区参与的核心原则保持一致。计划制定者在制定 "零愿景 "计划时,应考虑将 "安全系统 "原则转化为现实。
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引用次数: 0
Global, regional and national burdens of occupational injuries, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. 1990-2019年全球、地区和国家的职业伤害负担:2019年全球疾病负担研究的系统分析。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045149
Jianqiang Lai, Xianmin Li, Wei Liu, Qian Liufu, Chengfan Zhong

Objectives: Occupational injuries pose a significant challenge to global health and development. This study aimed to quantify the international and regional burdens of occupational injuries from 1990 to 2019, stratified by specific causes.

Methods: We analysed global trends in deaths, disability-adjusted life years (DALYs), age-standardised mortality rates (ASMR) and age-standardised DALY rates (ASDR) related to occupational injuries. Specific injuries, including animal contact, drowning, mechanical forces, falls, fire, heat, hot substances, foreign bodies, poisoning and road injuries, were evaluated. Age-stratified and regional analyses were also performed.

Results: Globally, the number of deaths, DALYs, ASMR and ASDR related to occupational injuries declined from 1990 to 2019. The middle Socio-demographic Index (SDI) region exhibited the highest burden, whereas the high SDI region showed the least burden. China and India had the highest occupational injury-related death rates in 2019. Males, particularly those aged 25-44 years, were found to be more vulnerable. Road injuries were the leading cause of death in all age groups. Compared with 1990, mortality numbers and rates decreased significantly by 2019, with the highest burdens experienced in East Asia, South Asia and Southeast Asia.

Conclusion: The global decline in occupational injuries is promising; however, certain regions and demographics remain disproportionately affected. Targeted interventions in high-burden areas are crucial to further reduce the impact of occupational injuries.

目的:职业伤害对全球健康和发展构成重大挑战。本研究旨在量化 1990 年至 2019 年期间国际和地区的职业伤害负担,并按具体原因进行分层:我们分析了与职业伤害相关的死亡人数、残疾调整生命年(DALYs)、年龄标准化死亡率(ASMR)和年龄标准化残疾调整生命年率(ASDR)的全球趋势。对特定伤害进行了评估,包括动物接触、溺水、机械力、坠落、火灾、高温、热物质、异物、中毒和道路伤害。此外,还进行了年龄分层和地区分析:结果:从 1990 年到 2019 年,全球与职业伤害相关的死亡人数、残疾调整寿命年数、ASMR 和 ASDR 均有所下降。中等社会人口指数(SDI)地区的负担最高,而高社会人口指数地区的负担最低。2019年,中国和印度的职业伤害相关死亡率最高。男性,尤其是 25-44 岁的男性更容易受到伤害。道路伤害是所有年龄组的主要死因。与 1990 年相比,到 2019 年,死亡人数和死亡率显著下降,其中东亚、南亚和东南亚的负担最重:全球职业伤害下降的趋势令人鼓舞;然而,某些地区和人口群体仍然受到不成比例的影响。在高负担地区采取有针对性的干预措施对于进一步减少职业伤害的影响至关重要。
{"title":"Global, regional and national burdens of occupational injuries, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.","authors":"Jianqiang Lai, Xianmin Li, Wei Liu, Qian Liufu, Chengfan Zhong","doi":"10.1136/ip-2023-045149","DOIUrl":"10.1136/ip-2023-045149","url":null,"abstract":"<p><strong>Objectives: </strong>Occupational injuries pose a significant challenge to global health and development. This study aimed to quantify the international and regional burdens of occupational injuries from 1990 to 2019, stratified by specific causes.</p><p><strong>Methods: </strong>We analysed global trends in deaths, disability-adjusted life years (DALYs), age-standardised mortality rates (ASMR) and age-standardised DALY rates (ASDR) related to occupational injuries. Specific injuries, including animal contact, drowning, mechanical forces, falls, fire, heat, hot substances, foreign bodies, poisoning and road injuries, were evaluated. Age-stratified and regional analyses were also performed.</p><p><strong>Results: </strong>Globally, the number of deaths, DALYs, ASMR and ASDR related to occupational injuries declined from 1990 to 2019. The middle Socio-demographic Index (SDI) region exhibited the highest burden, whereas the high SDI region showed the least burden. China and India had the highest occupational injury-related death rates in 2019. Males, particularly those aged 25-44 years, were found to be more vulnerable. Road injuries were the leading cause of death in all age groups. Compared with 1990, mortality numbers and rates decreased significantly by 2019, with the highest burdens experienced in East Asia, South Asia and Southeast Asia.</p><p><strong>Conclusion: </strong>The global decline in occupational injuries is promising; however, certain regions and demographics remain disproportionately affected. Targeted interventions in high-burden areas are crucial to further reduce the impact of occupational injuries.</p>","PeriodicalId":13682,"journal":{"name":"Injury Prevention","volume":" ","pages":"52-59"},"PeriodicalIF":2.5,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141093208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New motivation for injury prevention in the face of dramatic demographic changes in China.
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2024-045578
Wanbao Ye, Shuxian Yu, Zhaojing Yang, Liping Li

Our manuscript reviewed the enormous number of deaths caused by different types of injuries in China and around the world and proposed a new motivation for injury prevention to address sharp demographic changes and promote constant economic growth when China faces ageing, fewer children and industrial upgrading.

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引用次数: 0
Physical and psychological factors related to injury, illness and tactical performance in law enforcement recruits: a systematic review. 与执法新兵受伤、生病和战术表现有关的生理和心理因素:系统综述。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-23 DOI: 10.1136/ip-2023-045150
Myles Murphy, Nicole Merrick, Gill Cowen, Vanessa Sutton, Garth Allen, Nicolas H Hart, Andrea B Mosler

Objective: There are inconsistent reports of factors relating to injury, illness and tactical performance in law enforcement recruits. Our objectives were to: (1) report physical and psychological risk factors and protective factors for injury and illness and (2) report physical and psychological risk factors and protective factors for tactical performance success.

Design: Systematic epidemiological review.

Methods: Searches of six databases were conducted on 13 December 2022. We included cohorts that assessed physical and psychological factors for injury, illness and tactical performance success. Study quality was assessed using the Joanna Briggs Institute Quality Assessment Checklist for Prevalence Studies and certainty assessed using the Grading of Recommendations Assessment, Development and Evaluation.

Results: 30 studies were included, and quality assessment was performed. Very low certainty of evidence exists for physical variables related to injury risk, and we found no studies that investigated psychological variables as a risk factor for injury. Low-certainty evidence found older age, poorer performance with push-up reps to failure, poorer arm ergometer revolutions, poorer beep test, poorer 75-yard pursuit and the 1.5 miles run tests to be associated with reduced tactical performance. Very low certainty of evidence exists that the psychological variables of intelligence and anger are associated with tactical performance.

Conclusions: We identified a lack of high-level evidence for factors associated with injury, illness and performance. Interventions based on this research will be suboptimal. We suggest context-specific factors related to injury, illness and performance in law enforcement populations are used to inform current practice while further, high-quality research into risk factors is performed.

Prospero registration number: CRD42022381973.

目的:关于执法新兵受伤、生病和战术表现的相关因素的报告并不一致。我们的目标是(1)报告伤病的生理和心理风险因素及保护因素;(2)报告战术表现成功的生理和心理风险因素及保护因素:设计:系统流行病学回顾:2022 年 12 月 13 日对六个数据库进行了检索。我们纳入了评估伤病和战术表现成功的生理和心理因素的队列。研究质量采用乔安娜-布里格斯研究所流行病学研究质量评估检查表进行评估,确定性采用建议分级评估、发展和评价进行评估:结果:共纳入 30 项研究,并进行了质量评估。与受伤风险相关的身体变量的证据确定性很低,我们没有发现调查心理变量作为受伤风险因素的研究。低确定性证据发现,年龄越大、俯卧撑失败次数越多、臂力器转数越少、哔哔声测试越少、75 码追逐和 1.5 英里跑步测试越少与战术表现下降有关。智力和愤怒等心理变量与战术表现相关的证据确定性很低:我们发现,与伤病和表现相关的因素缺乏高水平的证据。基于这些研究的干预措施将是次优的。我们建议在对风险因素进行进一步的高质量研究的同时,利用执法人群中与受伤、疾病和表现相关的特定环境因素来指导当前的实践:CRD42022381973。
{"title":"Physical and psychological factors related to injury, illness and tactical performance in law enforcement recruits: a systematic review.","authors":"Myles Murphy, Nicole Merrick, Gill Cowen, Vanessa Sutton, Garth Allen, Nicolas H Hart, Andrea B Mosler","doi":"10.1136/ip-2023-045150","DOIUrl":"10.1136/ip-2023-045150","url":null,"abstract":"<p><strong>Objective: </strong>There are inconsistent reports of factors relating to injury, illness and tactical performance in law enforcement recruits. Our objectives were to: (1) report physical and psychological risk factors and protective factors for injury and illness and (2) report physical and psychological risk factors and protective factors for tactical performance success.</p><p><strong>Design: </strong>Systematic epidemiological review.</p><p><strong>Methods: </strong>Searches of six databases were conducted on 13 December 2022. We included cohorts that assessed physical and psychological factors for injury, illness and tactical performance success. Study quality was assessed using the Joanna Briggs Institute Quality Assessment Checklist for Prevalence Studies and certainty assessed using the Grading of Recommendations Assessment, Development and Evaluation.</p><p><strong>Results: </strong>30 studies were included, and quality assessment was performed. Very low certainty of evidence exists for physical variables related to injury risk, and we found no studies that investigated psychological variables as a risk factor for injury. Low-certainty evidence found older age, poorer performance with push-up reps to failure, poorer arm ergometer revolutions, poorer beep test, poorer 75-yard pursuit and the 1.5 miles run tests to be associated with reduced tactical performance. Very low certainty of evidence exists that the psychological variables of intelligence and anger are associated with tactical performance.</p><p><strong>Conclusions: </strong>We identified a lack of high-level evidence for factors associated with injury, illness and performance. Interventions based on this research will be suboptimal. We suggest context-specific factors related to injury, illness and performance in law enforcement populations are used to inform current practice while further, high-quality research into risk factors is performed.</p><p><strong>Prospero registration number: </strong>CRD42022381973.</p>","PeriodicalId":13682,"journal":{"name":"Injury Prevention","volume":" ","pages":"9-17"},"PeriodicalIF":2.5,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in alcohol, MDMA, methylamphetamine and THC in injured and deceased motor vehicle drivers and motorcyclists over a decade (2010-2019) in Victoria, Australia. 澳大利亚维多利亚州十年来(2010-2019年)受伤和死亡的机动车驾驶员和摩托车手中酒精、摇头丸、甲基安非他明和四氢大麻酚的趋势。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-21 DOI: 10.1136/ip-2024-045342
Jennifer Schumann, Matthew Di Rago, Noel Woodford, Linda Glowacki, John Fitzpatrick, Michael Kelly, Ben Beck, Olaf H Drummer, Dimitri Gerostamoulos, Joanna F Dipnall

Background: Driving under the influence of alcohol and other drugs contributes significantly to road traffic crashes worldwide. This study explored trends of alcohol, methylamphetamine (MA), 3,4-methylenedioxy-N-methylamphetamine (MDMA) and Δ9-tetrahydrocannabinol (THC), in road crashes from 2010 to 2019 in Victoria, Australia.

Methods: We conducted a cross-sectional analysis using data from the Victorian Institute of Forensic Medicine and Victoria Police, examining proscribed drug detections in road crashes. Time series graphs per substance explored indicative trends and comparisons between road users. Negative binomial regression models, with robust SEs and adjusted for exposure (kilometres travelled, Victorian licence holders), modelled the incidence rate ratio, with a Bonferroni-adjusted α=0.007 for multiple comparisons.

Results: There were 19 843 injured drivers and 1596 fatally injured drivers. MA had the highest prevalence (12.3% of fatalities and 9.1% of injured drivers), demonstrating an increase over time. Overall, 16.8% of car drivers and motorcyclists tested positive for one or more drugs, with 14% of crashes involving a blood alcohol concentration (BAC)≥0.05%. MA and THC were the most common drugs in fatalities. Between 2015 and 2019, MA was detected in 27.9% of motorcyclist fatalities, followed by THC (18.3%) and alcohol ≥0.05% (14.2%), with similar but lower frequencies among injured motorcyclists. Alcohol detections (≥0.05% BAC) in fatalities declined, but increased in injured motorcyclists and car drivers until plateauing in 2017. THC detections rose among injured drivers until 2018, detected in 8.1% and 15.2% of injured and fatal drivers, respectively. MDMA-positive driving decreased among injured drivers and remained stable at ~1% of fatalities.

Conclusions: Despite enhanced road safety measures in Victoria, drug-driving persists, indicating a need for revised prevention strategies targeting this growing issue.

背景:在酒精和其他药物影响下驾驶在很大程度上造成了世界各地的道路交通事故。本研究探讨了酒精、甲基安非他明(MA)、3,4-亚甲基二氧基- n -甲基安非他明(MDMA)和Δ9-tetrahydrocannabinol (THC)在2010年至2019年澳大利亚维多利亚州道路交通事故中的趋势。方法:我们使用维多利亚法医研究所和维多利亚警方的数据进行了横断面分析,检查了道路交通事故中违禁药物的检测。每种物质的时间序列图探讨了道路使用者之间的指示性趋势和比较。负二项回归模型具有稳健的se,并调整了暴露(行驶公里,维多利亚州执照持有人),模拟了发病率比,多重比较采用bonferroni调整的α=0.007。结果:共有19 843名驾驶员受伤,1596名驾驶员重伤。MA的患病率最高(占死亡人数的12.3%和受伤司机的9.1%),随着时间的推移呈上升趋势。总体而言,16.8%的汽车司机和摩托车手对一种或多种药物的检测呈阳性,14%的撞车事故涉及血液酒精浓度(BAC)≥0.05%。MA和THC是导致死亡的最常见药物。2015年至2019年期间,在27.9%的摩托车手死亡病例中检测到MA,其次是四氢大麻酚(18.3%)和酒精≥0.05%(14.2%),在受伤的摩托车手中检测到MA的频率相似但较低。酒精检测(酒精浓度≥0.05%)在死亡人数中有所下降,但在受伤的摩托车手和汽车司机中有所增加,直到2017年达到稳定水平。直到2018年,受伤司机中四氢大麻酚的检测率有所上升,分别在8.1%和15.2%的受伤和致命司机中检测到。mdma阳性驾驶在受伤司机中减少,并保持稳定在约1%的死亡人数。结论:尽管维多利亚州加强了道路安全措施,但毒品驾驶仍然存在,表明需要针对这一日益严重的问题修订预防战略。
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引用次数: 0
Predicting 90-day return to the emergency department in orthopaedic trauma patients in the Southeastern USA: a machine-learning approach. 预测美国东南部骨科创伤患者90天内返回急诊室:一种机器学习方法。
IF 2.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-21 DOI: 10.1136/ip-2024-045358
Bruno Valan, Aaron Therien, Emily Peairs, Solomon Ayehu, Joshua Taylor, Daniel Zeng, Steven Olson, Rachel Reilly, Christian Pean, Malcolm DeBaun

Introduction: Return-to-acute-care metrics, such as early emergency department (ED) visits, are key indicators of healthcare quality, with ED returns following surgery often considered avoidable and costly events. Proactively identifying patients at high risk of ED return can support quality improvement efforts, allowing interventions to target vulnerable patients. With its predictive capabilities, machine learning (ML) has shown potential in forecasting various clinical outcomes but remains underutilised in orthopaedic trauma. This study uses a random forest model to predict 90-day ED return in orthopaedic trauma patients, aiming to identify high-risk individuals and elucidate risk factors associated with returns. This study hypothesised that a highly accurate model could be developed to predict patients at high risk of ED return within 90 days of surgery.

Purpose: To develop and validate an ML model that predicts 90-day ED returns after orthopaedic trauma surgery using input data readily available in the electronic health record.

Methods: This is a retrospective model development and validation study. The study used data from a registry that includes information on all orthopaedic surgeries conducted at a level 1 academic medical centre. Patients who underwent orthopaedic trauma between 1 January 2017 and 1 March 2023 were identified using common procedural terminology code. The model used demographic, comorbid and perioperative variables. Return to the ED was captured as a binary outcome. Model performance was evaluated using the area under the receiver operator curve (AUROC).

Results: A total of 12 069 patients met the inclusion criteria. Patients were predominantly female (53%) and white (70%), with a median age of 55. The 90-day ED return rate was 14% (table 1). The random forest model identified body mass index, distance from the patient's residence to the hospital, age, length of hospital stay and complexity of procedure (work relative value unit) as significant predictors of ED return, each accounting for greater than 10% of the total importance across all features in the model (table 2). Further, the model displayed strong discrimination of patients returning to the ED (AUROC=0.74) (figure 1).

Conclusions: The random forest model demonstrated predictive discrimination of 90-day ED returns. Critical predictors such as patient distance from the hospital suggest considering geographical and socioeconomic factors in postdischarge care planning. Operational factors such as length of stay or complexity of the procedure also predicted return to the ED. The study lays the groundwork for future predictive models in clinical decision-making and healthcare resource utilisation.

Level of evidence: Level III, retrospective model development and validation study.

急诊复诊指标,如早期急诊科(ED)访问,是医疗质量的关键指标,手术后的急诊复诊通常被认为是可避免的和昂贵的事件。主动识别ED复发风险高的患者可以支持质量改进工作,使干预措施能够针对弱势患者。凭借其预测能力,机器学习(ML)在预测各种临床结果方面显示出潜力,但在骨科创伤方面仍未得到充分利用。本研究采用随机森林模型预测骨科创伤患者90天ED复发,旨在识别高危人群并阐明与复发相关的危险因素。本研究假设可以建立一个高度精确的模型来预测手术后90天内ED复发的高风险患者。目的:开发并验证一个ML模型,该模型使用电子健康记录中现成的输入数据预测骨科创伤手术后90天ED复发。方法:采用回顾性模型开发与验证研究。该研究使用的数据来自一个登记处,其中包括在一级学术医疗中心进行的所有骨科手术的信息。2017年1月1日至2023年3月1日期间接受骨科创伤的患者使用通用程序术语代码进行识别。该模型使用人口统计学、合并症和围手术期变量。返回急诊室被捕获为二进制结果。采用接收算子曲线下面积(AUROC)评价模型性能。结果:共有12069例患者符合纳入标准。患者以女性(53%)和白人(70%)为主,中位年龄为55岁。90天ED复复率为14%(表1)。随机森林模型确定体重指数、患者住所到医院的距离、年龄、住院时间和手术复杂性(工作相对价值单位)是ED复复率的重要预测因子,每一个都占模型中所有特征总重要性的10%以上(表2)。该模型对患者返回ED表现出很强的辨别能力(AUROC=0.74)(图1)。结论:随机森林模型对90天ED复发具有预测性辨别能力。关键的预测因素,如患者与医院的距离,建议在出院后护理计划中考虑地理和社会经济因素。手术因素,如住院时间或手术的复杂性,也可以预测返回急诊室。该研究为临床决策和医疗资源利用的未来预测模型奠定了基础。证据等级:III级,回顾性模型开发和验证研究。
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Injury Prevention
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