Background: Dentine hypersensitivity (DH) is a common oral condition. The management of DH has been challenging with various treatment options, including in-office and home care.
Objective: To evaluate the efficacy of hydroxyapatite-containing toothpaste for the reduction of DH pain compared to potassium nitrate-containing toothpaste in short-term use.
Methods: A randomised; non-blinded clinical study involved 39 participants in the age group range 18-51 years. The patients were randomly divided into two groups. The test group (n = 19) was provided with hydroxyapatite toothpaste, while the control group (n = 20) received potassium nitrate toothpaste. Volunteers were examined using an air blast as the stimulus. DH pain scores (Visual Analogue Scale [VAS] and Schiff) were recorded at baseline, 2 weeks and 4 weeks.
Results: Both toothpastes significantly relieved DH in response to air-blast stimulus (p < 0.001). The relief of sensitivity was efficacious after 2 and 4 weeks for both toothpastes. The efficacy of hydroxyapatite toothpaste was comparable to that of potassium nitrate toothpaste.
Conclusion: This study shows that hydroxyapatite in higher concentrations has a similar efficacy in relieving DH as potassium nitrate.
Clinical significance: DH affects the quality of life. The use of a desensitising toothpaste can relieve DH. However, there is no gold-standard management for DH. The outcome of this study supports the use of hydroxyapatite toothpaste for DH relief.