Pub Date : 2024-01-08DOI: 10.1097/ipc.0000000000001336
Marwa N. Alsaraj, M. Qazzaz, M. Abed, F. Alassaf, M. Alfahad, Mahmood H. M. Jasim
Favipiravir and remdesivir have recently received more clinical interest for the management of COVID-19. The study aimed to explore the effectiveness of favipiravir or remdesivir on the clinical outcome of SARS-CoV-2 patients in comparison with standard care. All patients were given standard care before being randomized into the following 3 groups: standard care group (standard care only), remdesivir group (remdesivir and standard care), and favipiravir group (group 3, favipiravir and standard care). The primary endpoint of the study was time to recovery or the clinical condition of patients on day 14. A total of 156 patients underwent randomization (53 assigned to standard care group, 51 to favipiravir group, and 52 to remdesivir group). The percentage of death in favipiravir and remdesivir groups was higher than those in the standard care group and likewise the liver enzymes. Studying the time to starting therapy showed that early administration of antivirals resulted in lower percentage of mortality. The ratio of hazard for early favipiravir and remdesivir was lower in comparison with those treated with late administration of the same drugs (hazard ratio, 0.62; 95% confidence interval [CI], 0.62–0.73 vs 3.22; 95% CI, 3.21–3.44, respectively, for favipiravir and 0.11; 95% CI, 0.10–0.12 vs 3.44; 95% CI, 3.43–3.55, respectively, for remdesivir). For favipiravir or remdesivir to have more beneficial effects than standard care alone for SARS-CoV-2 patients, they need to be started as early as possible. However, regular monitoring of liver function is required.
{"title":"Consequence of Antivirals Versus Standard Care on Clinical Situation in Patients With COVID-19","authors":"Marwa N. Alsaraj, M. Qazzaz, M. Abed, F. Alassaf, M. Alfahad, Mahmood H. M. Jasim","doi":"10.1097/ipc.0000000000001336","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001336","url":null,"abstract":"\u0000 Favipiravir and remdesivir have recently received more clinical interest for the management of COVID-19. The study aimed to explore the effectiveness of favipiravir or remdesivir on the clinical outcome of SARS-CoV-2 patients in comparison with standard care. All patients were given standard care before being randomized into the following 3 groups: standard care group (standard care only), remdesivir group (remdesivir and standard care), and favipiravir group (group 3, favipiravir and standard care). The primary endpoint of the study was time to recovery or the clinical condition of patients on day 14. A total of 156 patients underwent randomization (53 assigned to standard care group, 51 to favipiravir group, and 52 to remdesivir group). The percentage of death in favipiravir and remdesivir groups was higher than those in the standard care group and likewise the liver enzymes. Studying the time to starting therapy showed that early administration of antivirals resulted in lower percentage of mortality. The ratio of hazard for early favipiravir and remdesivir was lower in comparison with those treated with late administration of the same drugs (hazard ratio, 0.62; 95% confidence interval [CI], 0.62–0.73 vs 3.22; 95% CI, 3.21–3.44, respectively, for favipiravir and 0.11; 95% CI, 0.10–0.12 vs 3.44; 95% CI, 3.43–3.55, respectively, for remdesivir). For favipiravir or remdesivir to have more beneficial effects than standard care alone for SARS-CoV-2 patients, they need to be started as early as possible. However, regular monitoring of liver function is required.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"34 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139447804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.1097/ipc.0000000000001337
V. Lobo Antuña, M. Lobo Antuña, Alejandro Fernández Soro, Benjamín Climent
Slamming is a widespread sexual practice that has been occurring in our society for more than a decade now. It has emerged as a public health issue because it associates many harm and risks, mainly derived from unsafe sexual practice and intravenous drug abuse. In the recent years, an additional concern has emerged regarding the rising occurrence of multidrug-resistant bacteria within the community, particularly strains of methicillin-resistant Staphylococcus aureus (S. aureus). In this report, we present the case of a human immunodeficiency virus patient addicted to parenteral-synthetic-cathinone use in the context of slamming, which developed necrotizing fasciitis by this resistant strain. As prevention measures, assuming the inevitability of slamming practices, harm reduction programs have been developed. Implemented for years, they aim to reduce the risks of addictive behaviors. This clinical case raises the question of whether methicillin-resistant S. aureus carrier screening and consequent decolonization among people who inject drugs, and more specifically among those engaged in slamming, should be included in the daily practice as another tool of these harm reduction programs.
{"title":"Screening and Decolonization Programs for Staphylococcus aureus Carriers in the Slamming-Practice Community: A New Strategy for Harm Reduction?","authors":"V. Lobo Antuña, M. Lobo Antuña, Alejandro Fernández Soro, Benjamín Climent","doi":"10.1097/ipc.0000000000001337","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001337","url":null,"abstract":"\u0000 Slamming is a widespread sexual practice that has been occurring in our society for more than a decade now. It has emerged as a public health issue because it associates many harm and risks, mainly derived from unsafe sexual practice and intravenous drug abuse. In the recent years, an additional concern has emerged regarding the rising occurrence of multidrug-resistant bacteria within the community, particularly strains of methicillin-resistant Staphylococcus aureus (S. aureus). In this report, we present the case of a human immunodeficiency virus patient addicted to parenteral-synthetic-cathinone use in the context of slamming, which developed necrotizing fasciitis by this resistant strain. As prevention measures, assuming the inevitability of slamming practices, harm reduction programs have been developed. Implemented for years, they aim to reduce the risks of addictive behaviors. This clinical case raises the question of whether methicillin-resistant S. aureus carrier screening and consequent decolonization among people who inject drugs, and more specifically among those engaged in slamming, should be included in the daily practice as another tool of these harm reduction programs.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"44 24","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139446324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.1097/ipc.0000000000001338
Lana Abusalem, A. M. Roy, Shagufta Siddiqui, Anissa Hodges, Priyenka Thapa, Ryan Dare
Schistosomiasis is a neglected tropical disease that remains a major threat to global health. Schistosoma is known to cause chronic urogenital infections with an increased risk of bladder carcinomas. We present a case of chronic latent Schistosoma haematobium infection in a US veteran identified several years after his active military duty in Iraq and Kuwait. This case highlights the need for proactive screening of returning veterans from endemic areas. It also leads us to wonder how many infected veterans remain undiagnosed, and how many of those who develop urothelial carcinomas had prior exposure to schistosomiasis during their service.
{"title":"A Tale of Mummified Eggs in Urine of a US Veteran","authors":"Lana Abusalem, A. M. Roy, Shagufta Siddiqui, Anissa Hodges, Priyenka Thapa, Ryan Dare","doi":"10.1097/ipc.0000000000001338","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001338","url":null,"abstract":"\u0000 Schistosomiasis is a neglected tropical disease that remains a major threat to global health. Schistosoma is known to cause chronic urogenital infections with an increased risk of bladder carcinomas. We present a case of chronic latent Schistosoma haematobium infection in a US veteran identified several years after his active military duty in Iraq and Kuwait. This case highlights the need for proactive screening of returning veterans from endemic areas. It also leads us to wonder how many infected veterans remain undiagnosed, and how many of those who develop urothelial carcinomas had prior exposure to schistosomiasis during their service.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"57 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139447246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.1097/ipc.0000000000001352
David J. Cennimo
{"title":"Lessons From the Mpox Education and Vaccination Campaign","authors":"David J. Cennimo","doi":"10.1097/ipc.0000000000001352","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001352","url":null,"abstract":"","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"3 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138973145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.1097/ipc.0000000000001303
Casey N. Pinto, Kathryn A. Risher, William Calo, Jennifer Kraschnewski, Emily S Heilbrunn, Catharine I. Paules
Little has been reported about mpox knowledge and vaccine willingness. We sought to collect timely data on mpox knowledge, perceived risk, and vaccine willingness among a representative sample of Pennsylvania adults. A cross-sectional web-based survey was conducted in September 2022. Four survey items were included to assess the population's knowledge and risk awareness surrounding the current mpox outbreak, and vaccine willingness if at risk for mpox. Data analyses included descriptive statistics and logistic regressions. Among 1039 survey respondents, few reported “no knowledge of mpox symptoms” (14.2%) or transmission modalities (12.5%). Those who perceived themselves at moderate/high risk were more likely to report knowing mpox symptoms (adjusted odds ratio [aOR] = 2.12) vs no risk. Men who have sex with men were more likely to know that mpox can mimic a sexually transmitted infection (aOR = 3.125), less likely to report not knowing any modes of transmission (aOR = 0.17), and more willing to be vaccinated (aOR = 4.35) than women who have sex with men. Self-perceived mpox risk was associated with willingness to get vaccinated (aOR low risk vs no risk = 3.45 [2.42–4.92], aOR moderate/high risk vs no risk = 9.93 [5.81–16.99]). Knowledge of mpox symptoms and transmission is strong in Pennsylvania, specifically among high-risk groups, but lacks a nuanced understanding specific to the current outbreak. Willingness to receive an mpox vaccine is highest in men who have sex with men and those that perceive themselves to be at highest risk. These findings highlight the need for more education on symptoms of the current outbreak and research on impact of the education on vaccine hesitancy.
{"title":"Mpox Knowledge and Vaccine Willingness Among a Representative Analysis of Adults in Pennsylvania","authors":"Casey N. Pinto, Kathryn A. Risher, William Calo, Jennifer Kraschnewski, Emily S Heilbrunn, Catharine I. Paules","doi":"10.1097/ipc.0000000000001303","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001303","url":null,"abstract":"\u0000 \u0000 Little has been reported about mpox knowledge and vaccine willingness. We sought to collect timely data on mpox knowledge, perceived risk, and vaccine willingness among a representative sample of Pennsylvania adults.\u0000 \u0000 \u0000 \u0000 A cross-sectional web-based survey was conducted in September 2022. Four survey items were included to assess the population's knowledge and risk awareness surrounding the current mpox outbreak, and vaccine willingness if at risk for mpox. Data analyses included descriptive statistics and logistic regressions.\u0000 \u0000 \u0000 \u0000 Among 1039 survey respondents, few reported “no knowledge of mpox symptoms” (14.2%) or transmission modalities (12.5%). Those who perceived themselves at moderate/high risk were more likely to report knowing mpox symptoms (adjusted odds ratio [aOR] = 2.12) vs no risk. Men who have sex with men were more likely to know that mpox can mimic a sexually transmitted infection (aOR = 3.125), less likely to report not knowing any modes of transmission (aOR = 0.17), and more willing to be vaccinated (aOR = 4.35) than women who have sex with men. Self-perceived mpox risk was associated with willingness to get vaccinated (aOR low risk vs no risk = 3.45 [2.42–4.92], aOR moderate/high risk vs no risk = 9.93 [5.81–16.99]).\u0000 \u0000 \u0000 \u0000 Knowledge of mpox symptoms and transmission is strong in Pennsylvania, specifically among high-risk groups, but lacks a nuanced understanding specific to the current outbreak. Willingness to receive an mpox vaccine is highest in men who have sex with men and those that perceive themselves to be at highest risk. These findings highlight the need for more education on symptoms of the current outbreak and research on impact of the education on vaccine hesitancy.\u0000","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"2021 15","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139001920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.1097/ipc.0000000000001312
Basil Al-kaabneh, R. Alpizar-Rivas, S. Chuang, Purba Gupta
We report a rare case of a liver transplant recipient who experienced acute respiratory failure early posttransplantation because of cryptococcal pleural effusion. Although cryptococcal disease presenting solely as pleural effusion has been reported in the literature, it is not widely described in liver transplant recipients. Cryptococcal disease usually manifests late in the posttransplant period, whereas our patient was diagnosed with the infection early posttransplant. Diagnosis was made by pleural fluid culture. The initial serum cryptococcal antigen testing was negative. This case demonstrates the potential of subclinical or latent infections in patients with cirrhosis and liver transplant recipients and the importance of considering pleural fluid culture in the diagnostic evaluation of pleural effusions in cirrhotic patients.
{"title":"Cryptococcal Infection Presenting as a Pleural Effusion in a Liver Transplant Recipient","authors":"Basil Al-kaabneh, R. Alpizar-Rivas, S. Chuang, Purba Gupta","doi":"10.1097/ipc.0000000000001312","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001312","url":null,"abstract":"\u0000 We report a rare case of a liver transplant recipient who experienced acute respiratory failure early posttransplantation because of cryptococcal pleural effusion. Although cryptococcal disease presenting solely as pleural effusion has been reported in the literature, it is not widely described in liver transplant recipients. Cryptococcal disease usually manifests late in the posttransplant period, whereas our patient was diagnosed with the infection early posttransplant. Diagnosis was made by pleural fluid culture. The initial serum cryptococcal antigen testing was negative. This case demonstrates the potential of subclinical or latent infections in patients with cirrhosis and liver transplant recipients and the importance of considering pleural fluid culture in the diagnostic evaluation of pleural effusions in cirrhotic patients.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"16 20","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139010464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.1097/ipc.0000000000001319
Bilal Irfan, Ihsaan Yasin, Aneela Yaqoob
{"title":"TikTok's Role in the COVID-19 Pandemic: An Analysis of the Spread of Treatment Information","authors":"Bilal Irfan, Ihsaan Yasin, Aneela Yaqoob","doi":"10.1097/ipc.0000000000001319","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001319","url":null,"abstract":"","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"18 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138980139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.1097/ipc.0000000000001318
Maisam Amar, Gabriel Weber, Rabah Yassin, Ola Salah, Pninit Shaked Mishan, Maya Brudenski, Shereen Shehade, R. Najjar-Debbiny
Bacille Calmette-Guérin wash for urothelial carcinoma is a very common adjuvant treatment with a low potential for serious systemic adverse events. We present a case of a rare serious complication, empyema necessitans, following treatment with BCG. A 77-year-old patient with urothelial cancer treated with adjuvant BCG wash developed empyema due to Mycobacterium bovis related to his previous BCG exposure, which progressed to empyema necessitans treated with antituberculosis medications in conjugant with multiple thoracic drainages. Despite treatment, the patient's condition deteriorated slowly leading to death. Rare adverse events of common treatments should be considered when evaluating a patient, as BCG wash could potentially lead to empyema necessitans.
{"title":"Empyema Necessitans Following Bacille Calmette-Guérin Administration for Urothelial Carcinoma","authors":"Maisam Amar, Gabriel Weber, Rabah Yassin, Ola Salah, Pninit Shaked Mishan, Maya Brudenski, Shereen Shehade, R. Najjar-Debbiny","doi":"10.1097/ipc.0000000000001318","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001318","url":null,"abstract":"\u0000 \u0000 Bacille Calmette-Guérin wash for urothelial carcinoma is a very common adjuvant treatment with a low potential for serious systemic adverse events. We present a case of a rare serious complication, empyema necessitans, following treatment with BCG.\u0000 \u0000 \u0000 \u0000 A 77-year-old patient with urothelial cancer treated with adjuvant BCG wash developed empyema due to Mycobacterium bovis related to his previous BCG exposure, which progressed to empyema necessitans treated with antituberculosis medications in conjugant with multiple thoracic drainages. Despite treatment, the patient's condition deteriorated slowly leading to death.\u0000 \u0000 \u0000 \u0000 Rare adverse events of common treatments should be considered when evaluating a patient, as BCG wash could potentially lead to empyema necessitans.\u0000","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"13 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138978870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.1097/ipc.0000000000001331
Osejie Oriaifo, Melisa Pasli, Supriya Sivadanam, Brandon Tedder, Nim Chan, Olanrewaju K Adabale, Arthur Dilibe, Paul Cook
Cunninghamella spp are a group of filamentous fungi commonly found in soil and decaying matter and can cause infections in immunocompromised individuals, especially those undergoing chemotherapy or with hematologic malignancies. These infections can lead to a rapidly progressive and fatal outcome. Despite accounting for less than 10% of documented mucormycosis cases, disseminated Cunninghamella infections have a higher mortality rate when compared with other mucormycosis. We present the case of a patient with chronic myelogenous leukemia and myelodysplastic syndromes/myeloproliferative neoplasms overlap, receiving azacitidine, who initially presented with a diabetic foot ulcer infested with maggots. The patient rapidly developed respiratory distress and encephalopathy, with imaging revealing consolidation in the right upper lung lobe infected with Cunninghamella spp. Treatment with amphotericin B did not improve the patient's condition. Brain imaging also indicated a 24.4 × 16.9-mm lesion, and given the patient's comorbidities and disease progression, surgical intervention was not feasible. The patient was subsequently transitioned to comfort care.
{"title":"Rapid Progression of Cunninghamella Species Leading to Respiratory Compromise","authors":"Osejie Oriaifo, Melisa Pasli, Supriya Sivadanam, Brandon Tedder, Nim Chan, Olanrewaju K Adabale, Arthur Dilibe, Paul Cook","doi":"10.1097/ipc.0000000000001331","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001331","url":null,"abstract":"\u0000 \u0000 Cunninghamella spp are a group of filamentous fungi commonly found in soil and decaying matter and can cause infections in immunocompromised individuals, especially those undergoing chemotherapy or with hematologic malignancies. These infections can lead to a rapidly progressive and fatal outcome. Despite accounting for less than 10% of documented mucormycosis cases, disseminated Cunninghamella infections have a higher mortality rate when compared with other mucormycosis.\u0000 We present the case of a patient with chronic myelogenous leukemia and myelodysplastic syndromes/myeloproliferative neoplasms overlap, receiving azacitidine, who initially presented with a diabetic foot ulcer infested with maggots. The patient rapidly developed respiratory distress and encephalopathy, with imaging revealing consolidation in the right upper lung lobe infected with Cunninghamella spp. Treatment with amphotericin B did not improve the patient's condition. Brain imaging also indicated a 24.4 × 16.9-mm lesion, and given the patient's comorbidities and disease progression, surgical intervention was not feasible. The patient was subsequently transitioned to comfort care.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"3 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138981066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-11DOI: 10.1097/ipc.0000000000001314
Faisal Khan, Drew W Engers, Joshua A. Lieberman, Varsha Moudgal
Cat bite wound infections are common, and much is known about their bacteriology, pathogenesis, and management. We report a case of a rare Mycoplasma species from a cat bite causing tenosynovitis and septic arthritis of the hand, as well as distant prosthetic joint infection of the knee. The patient demonstrated poor clinical response to standard and expanded antibiotic regimens. Repeated surgical interventions were necessary until nucleic acid amplification revealed a previously undescribed Mycoplasma species that was effectively treated with the addition of doxycycline.
{"title":"Disseminated Infection With a Previously Undescribed Mycoplasma Species From a Cat Bite","authors":"Faisal Khan, Drew W Engers, Joshua A. Lieberman, Varsha Moudgal","doi":"10.1097/ipc.0000000000001314","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001314","url":null,"abstract":"\u0000 Cat bite wound infections are common, and much is known about their bacteriology, pathogenesis, and management. We report a case of a rare Mycoplasma species from a cat bite causing tenosynovitis and septic arthritis of the hand, as well as distant prosthetic joint infection of the knee. The patient demonstrated poor clinical response to standard and expanded antibiotic regimens. Repeated surgical interventions were necessary until nucleic acid amplification revealed a previously undescribed Mycoplasma species that was effectively treated with the addition of doxycycline.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"13 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138979597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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