Pub Date : 2023-10-31DOI: 10.1097/ipc.0000000000001316
Hossein Yarmohammadi, Seyyed-Alireza Motevalizadeh, Amir-Mohammad Asgari, Mohammad Keshavarzi, Ghasem Azimi
Background COVID-19 has a variety of presentations and complications, and this study aimed to report the incidence of COVID-19 patients presenting with pneumothorax and bronchopleural fistula (BPF). Methods Documents of hospitalized COVID-19 patients with positive SARS-COV-2 polymerase chain reaction tests were reviewed respectively, and patients presenting with pneumothorax were included. Laboratory data, treatment, and the outcome were also gathered for each patient. Results The incidence of COVID-19 patients presenting with pneumothorax and BPF was 0.93% and 0.62%, respectively. Three cases were determined, and all were male adults. Two had BPF and one received thoracotomy. These 2 patients had significantly elevated inflammatory markers. Patients were treated with antibiotics, corticosteroids, anticoagulants, remdesivir, and tocilizumab. Unfortunately, all expired as 2 patients had a cardiac arrest and one had a multiorgan failure. Conclusions Presenting with pneumothorax among COVID-19 patients is not common but needs appropriate management to prevent further complications. It seems that BPF, as a rarely reported complication of COVID-19, might be linked to the inflammatory storm and indicates poor prognosis.
{"title":"COVID-19 Patients Presenting With Pneumothorax and Bronchopleural Fistula","authors":"Hossein Yarmohammadi, Seyyed-Alireza Motevalizadeh, Amir-Mohammad Asgari, Mohammad Keshavarzi, Ghasem Azimi","doi":"10.1097/ipc.0000000000001316","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001316","url":null,"abstract":"Background COVID-19 has a variety of presentations and complications, and this study aimed to report the incidence of COVID-19 patients presenting with pneumothorax and bronchopleural fistula (BPF). Methods Documents of hospitalized COVID-19 patients with positive SARS-COV-2 polymerase chain reaction tests were reviewed respectively, and patients presenting with pneumothorax were included. Laboratory data, treatment, and the outcome were also gathered for each patient. Results The incidence of COVID-19 patients presenting with pneumothorax and BPF was 0.93% and 0.62%, respectively. Three cases were determined, and all were male adults. Two had BPF and one received thoracotomy. These 2 patients had significantly elevated inflammatory markers. Patients were treated with antibiotics, corticosteroids, anticoagulants, remdesivir, and tocilizumab. Unfortunately, all expired as 2 patients had a cardiac arrest and one had a multiorgan failure. Conclusions Presenting with pneumothorax among COVID-19 patients is not common but needs appropriate management to prevent further complications. It seems that BPF, as a rarely reported complication of COVID-19, might be linked to the inflammatory storm and indicates poor prognosis.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"297 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.1097/ipc.0000000000001304
Daniel Strayve, Jarom Ruby, Mustafa Abidalhassan, Gerald J. Hutfles, Kurt B. Schaberg, Dongguang Wei, Michael Corwin, Sepideh Gholami
Abstract We report a rare case of hepatic malakoplakia mimicking malignancy both in its clinical presentation and appearance on 4-phase computed tomography. This case highlights both an interesting variation by which this disease process can manifest and a multidisciplinary approach, which may be used to identify and treat future patients.
{"title":"Malignant Mimicry in a Rare Case of Hepatic Malakoplakia","authors":"Daniel Strayve, Jarom Ruby, Mustafa Abidalhassan, Gerald J. Hutfles, Kurt B. Schaberg, Dongguang Wei, Michael Corwin, Sepideh Gholami","doi":"10.1097/ipc.0000000000001304","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001304","url":null,"abstract":"Abstract We report a rare case of hepatic malakoplakia mimicking malignancy both in its clinical presentation and appearance on 4-phase computed tomography. This case highlights both an interesting variation by which this disease process can manifest and a multidisciplinary approach, which may be used to identify and treat future patients.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.1097/ipc.0000000000001330
Munshi Moyenuddin
{"title":"Future Pandemic Could Be Worse","authors":"Munshi Moyenuddin","doi":"10.1097/ipc.0000000000001330","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001330","url":null,"abstract":"","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"48 7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135870894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.1097/ipc.0000000000001309
Atousa Salehani, Ramesh Nathan
Abstract The incidence of infections with Candida parapsilosis has been increasing, and this fungus is the second most commonly isolated Candida species from blood cultures. It has an affinity for intravascular devices, prosthetic devices, and total parenteral nutrition. We describe an uncommonly reported case of breakthrough bloodstream infection with C. parapsilosis in a patient receiving chronic total parenteral nutrition who was receiving micafungin for Candida glabrata fungemia. We also briefly discuss the challenges of diagnosis and management of fungemia caused by different Candida species.
{"title":"The Battle of Two Fungi","authors":"Atousa Salehani, Ramesh Nathan","doi":"10.1097/ipc.0000000000001309","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001309","url":null,"abstract":"Abstract The incidence of infections with Candida parapsilosis has been increasing, and this fungus is the second most commonly isolated Candida species from blood cultures. It has an affinity for intravascular devices, prosthetic devices, and total parenteral nutrition. We describe an uncommonly reported case of breakthrough bloodstream infection with C. parapsilosis in a patient receiving chronic total parenteral nutrition who was receiving micafungin for Candida glabrata fungemia. We also briefly discuss the challenges of diagnosis and management of fungemia caused by different Candida species.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135870596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.1097/ipc.0000000000001326
Ahmed Elkhapery, Sheza Malik, Pratibha Chaudhary, Zeinab Abdalla, Chengu Niu, Tripti Jain, Soon Khai Low, Ali Abdelhay, Carlos Portales-Castillo, Omar Al Ali, Abdullah A. Orakzai, Michael N. Gurell, Maryrose Laguio-Vila
Abstract Fusobacteriae are anaerobic gram-negative bacilli, classically involved in the development of septic thrombophlebitis of the internal jugular vein in Lemierre syndrome. The goal of this study is to describe the various presentations, treatment course, and outcomes of patients with Fusobacterium liver abscess(es) and review available literature on this topic. We retrospectively reviewed our microbiologic database for positive cultures of Fusobacteriae species in a tertiary care hospital from July 2018 through November 2022 and identified 5 cases of liver abscess that involved Fusobacterium nucleatum species. Patients presented with a syndrome of fever and chills, abdominal pain, and nausea and vomiting. Laboratory investigations revealed leukocytosis and transaminitis, and imaging revealed liver abscess(es). The identification of the F. nucleatum bacteria involved invasive aspiration of the abscess in all but one case, where it was identified on blood cultures. One patient had a florid picture of sepsis and acute respiratory distress syndrome. All patients responded well with intravenous antibiotics and were discharged home to complete a prolonged course until radiographic resolution. In 3 patients, history and imaging were suggestive of possible sources that may have hematogenously spread to the liver, with history of recent appendectomy in 1 patient, possible appendicitis on computed tomography of the abdomen in another patient, and recent dental manipulation in the third patient. In conclusion, Fusobacteriae should be included in the differential diagnosis of liver abscess, especially in the setting of recent appendicitis or dental disease. Effective treatment includes surgical drainage when feasible and prolonged course of antibiotics with goal of radiologic resolution.
{"title":"Liver Abscesses Due to Fusobacterium nucleatum: A Case Series","authors":"Ahmed Elkhapery, Sheza Malik, Pratibha Chaudhary, Zeinab Abdalla, Chengu Niu, Tripti Jain, Soon Khai Low, Ali Abdelhay, Carlos Portales-Castillo, Omar Al Ali, Abdullah A. Orakzai, Michael N. Gurell, Maryrose Laguio-Vila","doi":"10.1097/ipc.0000000000001326","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001326","url":null,"abstract":"Abstract Fusobacteriae are anaerobic gram-negative bacilli, classically involved in the development of septic thrombophlebitis of the internal jugular vein in Lemierre syndrome. The goal of this study is to describe the various presentations, treatment course, and outcomes of patients with Fusobacterium liver abscess(es) and review available literature on this topic. We retrospectively reviewed our microbiologic database for positive cultures of Fusobacteriae species in a tertiary care hospital from July 2018 through November 2022 and identified 5 cases of liver abscess that involved Fusobacterium nucleatum species. Patients presented with a syndrome of fever and chills, abdominal pain, and nausea and vomiting. Laboratory investigations revealed leukocytosis and transaminitis, and imaging revealed liver abscess(es). The identification of the F. nucleatum bacteria involved invasive aspiration of the abscess in all but one case, where it was identified on blood cultures. One patient had a florid picture of sepsis and acute respiratory distress syndrome. All patients responded well with intravenous antibiotics and were discharged home to complete a prolonged course until radiographic resolution. In 3 patients, history and imaging were suggestive of possible sources that may have hematogenously spread to the liver, with history of recent appendectomy in 1 patient, possible appendicitis on computed tomography of the abdomen in another patient, and recent dental manipulation in the third patient. In conclusion, Fusobacteriae should be included in the differential diagnosis of liver abscess, especially in the setting of recent appendicitis or dental disease. Effective treatment includes surgical drainage when feasible and prolonged course of antibiotics with goal of radiologic resolution.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135931603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1097/ipc.0000000000001306
Aaja Alosious, Mariya Luvis, Roshitha Ann Shaji, Antriya Annie Tom
Abstract Background Dengue, a vector-borne viral infection, is a concern in the tropical and subtropical regions across the world. The rampant use of antibiotics in dengue patients in India reinforces the anticipated threat of emergence of antimicrobial resistance. Aim We aimed to retrospectively investigate the prescribing pattern of antibiotics and compare the clinical status of dengue patients treated with and without antibiotics. Methods Between January 2016 and December 2020 period, data of patients who tested positive for at least 1 of the 3 screening tests (nonstructural protein 1, immunoglobulin M, or immunoglobulin G) were collected from patient medical chart, and we assessed the clinical outcome of dengue patients treated with and without antibiotics. Results Of 370 patients, 196 (52.97%) were managed with antibiotics and 174 (47.02%) were managed without antibiotics along with other supportive measures. A peak in the percentage of prescriptions with antibiotics was seen in 2019, 168 (85.71%) were prescribed with a single antibiotic with a majority of them, and 56.6% received third generation cephalosporins. Only 46 (23.46%) had bacterial co-infection while 150 (76.53%) had no co-infection. Thirty-five patients (70%) with dengue hemorrhagic fever were clinically managed with antibiotics compared with 50% patients in the “dengue fever” category. Only 8% of patients with mild dengue were given 2 antibiotics, whereas 13% with moderate dengue and 16% with severe dengue were prescribed with 2 antibiotics. Conclusions The increased number of prescriptions with antibiotics for a viral infection when not recommended by the guideline may lead to emergence of antibiotic resistance in hospitals as well as community.
{"title":"Misuse of Antibiotics in Dengue Fever—A Contributor to Antimicrobial Resistance?","authors":"Aaja Alosious, Mariya Luvis, Roshitha Ann Shaji, Antriya Annie Tom","doi":"10.1097/ipc.0000000000001306","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001306","url":null,"abstract":"Abstract Background Dengue, a vector-borne viral infection, is a concern in the tropical and subtropical regions across the world. The rampant use of antibiotics in dengue patients in India reinforces the anticipated threat of emergence of antimicrobial resistance. Aim We aimed to retrospectively investigate the prescribing pattern of antibiotics and compare the clinical status of dengue patients treated with and without antibiotics. Methods Between January 2016 and December 2020 period, data of patients who tested positive for at least 1 of the 3 screening tests (nonstructural protein 1, immunoglobulin M, or immunoglobulin G) were collected from patient medical chart, and we assessed the clinical outcome of dengue patients treated with and without antibiotics. Results Of 370 patients, 196 (52.97%) were managed with antibiotics and 174 (47.02%) were managed without antibiotics along with other supportive measures. A peak in the percentage of prescriptions with antibiotics was seen in 2019, 168 (85.71%) were prescribed with a single antibiotic with a majority of them, and 56.6% received third generation cephalosporins. Only 46 (23.46%) had bacterial co-infection while 150 (76.53%) had no co-infection. Thirty-five patients (70%) with dengue hemorrhagic fever were clinically managed with antibiotics compared with 50% patients in the “dengue fever” category. Only 8% of patients with mild dengue were given 2 antibiotics, whereas 13% with moderate dengue and 16% with severe dengue were prescribed with 2 antibiotics. Conclusions The increased number of prescriptions with antibiotics for a viral infection when not recommended by the guideline may lead to emergence of antibiotic resistance in hospitals as well as community.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"47 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1097/ipc.0000000000001317
Eric Santana, Ken S. Rosenthal
Abstract Monoclonal antibodies (mabs) and small molecule Janus kinase (JAK) inhibitors (nibs) are useful for treating inflammatory disease, autoimmune disease, and tumors, especially leukemia. Inhibition or depletion of the cytokines or cells with these drugs can result in loss of important protection against certain microbial infections. Recurrences of tuberculosis, hepatitis B and C, and zoster are especially sensitive to immune depletion. The consequences of inhibition of cytokines, molecules, pathways and cells by these drugs are described, depicted, and tabulated.
{"title":"Ablative Treatment of Inflammatory and Other Diseases With Monoclonal Antibodies (Mabs) or Janus Kinases (Nibs) Increases Risk for Infection","authors":"Eric Santana, Ken S. Rosenthal","doi":"10.1097/ipc.0000000000001317","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001317","url":null,"abstract":"Abstract Monoclonal antibodies (mabs) and small molecule Janus kinase (JAK) inhibitors (nibs) are useful for treating inflammatory disease, autoimmune disease, and tumors, especially leukemia. Inhibition or depletion of the cytokines or cells with these drugs can result in loss of important protection against certain microbial infections. Recurrences of tuberculosis, hepatitis B and C, and zoster are especially sensitive to immune depletion. The consequences of inhibition of cytokines, molecules, pathways and cells by these drugs are described, depicted, and tabulated.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"32 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135412942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1097/ipc.0000000000001315
Phuong-Uyen Vo, Roger B. Chaffee, Joseph P. Myers
Background Pasteurella multocida , a gram-negative coccobacillus associated with dog, cat, and other animal contact, often causes human bite infection, cellulitis, and osteomyelitis, but infective endocarditis is rare. We present a patient with P. multocida aortic valve endocarditis whose animal exposure was contact with his dog's saliva from frequent licking of patient's skin in the perioral area. Case Presentation A 62-year-old man with successfully treated hepatitis C presented to hospital after a syncopal episode while chasing his dog. He had previously noted night sweats, fever, generalized weakness, and dyspnea on exertion. He denied bites or scratches but admitted allowing his dog to lick around his mouth. On presentation, he was in septic shock with lactic acidosis. White blood cell count was 20,000/μL. Pasteurella multocida was isolated from both admission blood cultures. The patient was treated with antimicrobial therapy and resuscitated. Transthoracic echocardiogram revealed critical bicuspid aortic valve stenosis with root abscess and ascending aortic aneurysm. Transesophageal echocardiogram showed reduced ejection fraction and severe aortic stenosis but no definitive vegetations. At surgery, there were nodular lesions on the aortic valve, left ventricular outflow tract perforation, and annular abscess of aortic valve. He had mechanical aortic valve replacement, annular reconstruction, and aortic aneurysm repair. The patient received 6 weeks of postoperative intravenous ceftriaxone and remained infection-free at 1-year follow-up visit.
{"title":"Heartbreak From Puppy Love: A Case of Pasteurella multocida Endocarditis and Review of the Literature","authors":"Phuong-Uyen Vo, Roger B. Chaffee, Joseph P. Myers","doi":"10.1097/ipc.0000000000001315","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001315","url":null,"abstract":"Background Pasteurella multocida , a gram-negative coccobacillus associated with dog, cat, and other animal contact, often causes human bite infection, cellulitis, and osteomyelitis, but infective endocarditis is rare. We present a patient with P. multocida aortic valve endocarditis whose animal exposure was contact with his dog's saliva from frequent licking of patient's skin in the perioral area. Case Presentation A 62-year-old man with successfully treated hepatitis C presented to hospital after a syncopal episode while chasing his dog. He had previously noted night sweats, fever, generalized weakness, and dyspnea on exertion. He denied bites or scratches but admitted allowing his dog to lick around his mouth. On presentation, he was in septic shock with lactic acidosis. White blood cell count was 20,000/μL. Pasteurella multocida was isolated from both admission blood cultures. The patient was treated with antimicrobial therapy and resuscitated. Transthoracic echocardiogram revealed critical bicuspid aortic valve stenosis with root abscess and ascending aortic aneurysm. Transesophageal echocardiogram showed reduced ejection fraction and severe aortic stenosis but no definitive vegetations. At surgery, there were nodular lesions on the aortic valve, left ventricular outflow tract perforation, and annular abscess of aortic valve. He had mechanical aortic valve replacement, annular reconstruction, and aortic aneurysm repair. The patient received 6 weeks of postoperative intravenous ceftriaxone and remained infection-free at 1-year follow-up visit.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"31 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1097/ipc.0000000000001298
Miraç Öz, Nasser E. Absieha, Umut Dilegelen, Burak Alper Zengin, Kaan Gündüz, Ebru Evren, Sevgi Saryal
Abstract Syphilis is a multisystem infection caused by the spirochete Treponema pallidum . A 63-year-old man admitted to the hospital with chest pain and rashes on the chest wall and hands for 14 days. Thorax computed tomography revealed multiple nodular shadows in the bilateral lower lobes of the lung. Skin lesions were considered compatible with secondary syphilis. The antibody test for syphilis was positive. Screening for other associated sexually transmitted diseases (serology for HIV, hepatitis C, and hepatitis B) was negative. A specific therapy with crystallized penicillin G 2.4 MIU was applied. The key features for secondary syphilis diagnosis were positive serologic tests for syphilis and complete recovery on thorax computed tomography after antisyphilitic treatment. Pulmonary involvement in secondary syphilis is considered a rare occurrence.
{"title":"Secondary Syphilis With Pulmonary Involvement","authors":"Miraç Öz, Nasser E. Absieha, Umut Dilegelen, Burak Alper Zengin, Kaan Gündüz, Ebru Evren, Sevgi Saryal","doi":"10.1097/ipc.0000000000001298","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001298","url":null,"abstract":"Abstract Syphilis is a multisystem infection caused by the spirochete Treponema pallidum . A 63-year-old man admitted to the hospital with chest pain and rashes on the chest wall and hands for 14 days. Thorax computed tomography revealed multiple nodular shadows in the bilateral lower lobes of the lung. Skin lesions were considered compatible with secondary syphilis. The antibody test for syphilis was positive. Screening for other associated sexually transmitted diseases (serology for HIV, hepatitis C, and hepatitis B) was negative. A specific therapy with crystallized penicillin G 2.4 MIU was applied. The key features for secondary syphilis diagnosis were positive serologic tests for syphilis and complete recovery on thorax computed tomography after antisyphilitic treatment. Pulmonary involvement in secondary syphilis is considered a rare occurrence.","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"74 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135412947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spiritual Health Is a Neglected Need in the Mental Rehabilitation of Nurses After the COVID-19 Pandemic","authors":"Tahereh Yaghoubi, Rahmatollah Marzband, Seyed Hamzeh Hosseini, Fereshteh Araghian Mojarad","doi":"10.1097/ipc.0000000000001299","DOIUrl":"https://doi.org/10.1097/ipc.0000000000001299","url":null,"abstract":"Yaghoubi, Tahereh; Marzband, Rahmatollah; Hosseini, Seyed Hamzeh; Mojarad, Fereshteh Araghian Author Information","PeriodicalId":13952,"journal":{"name":"Infectious Diseases in Clinical Practice","volume":"13 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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