Pub Date : 2018-03-18DOI: 10.17554/J.ISSN.2313-5611.2018.04.73
M. Faizal, A. Khan
AIM: To assess the hyperglycemia-induced microscopic changes in the posterior pituitary of streptozotocin (STZ) - induced diabetic adult albino rats. MATERIAL AND METHODS: After clearance from the Institutional Animal Ethical Committee, 36 animals were divided into six groups having six rats each: control, two weeks, one month, two months, four months and six months. Diabetes was induced with a single dose of streptozotocin administered through intraperitoneal route (60 mg/kg). Body weight and blood sugar were monitored at the biweekly interval. At the end of each experimental period, animals were euthanized by deep ether anesthesia and blood samples were collected by direct puncture of heart for biochemical analysis. Tissues were fixed in Karnovsky fixative and processed for paraffin sectioning. Routine and special stained sections were studied under the light microscope and relevant findings were recorded. RESULTS: Data obtained from biochemical analyses and histomorphometry along with the histopathological features revealed that with increasing duration of hyperglycemia was associated with increased serum creatinine and reduction in serum total protein; increased mean percentage of darkly stained large sized pituicytes and notable thickening of perisinusoidal collagen. CONCLUSION: It is therefore concluded that long-standing hyperglycemia which is associated with increased occurrence of predominantly large and darkly stained pituicytes and remarkably increased deposition of perisinusoidal collagen appear to be the important contributing factors somehow responsible for the derangement of the function of the posterior pituitary in chronic diabetes.
{"title":"A Histomorphometric Study on the Neurohypophysis of STZ-induced Diabetic Albino Rats","authors":"M. Faizal, A. Khan","doi":"10.17554/J.ISSN.2313-5611.2018.04.73","DOIUrl":"https://doi.org/10.17554/J.ISSN.2313-5611.2018.04.73","url":null,"abstract":"AIM: To assess the hyperglycemia-induced microscopic changes in the posterior pituitary of streptozotocin (STZ) - induced diabetic adult albino rats. MATERIAL AND METHODS: After clearance from the Institutional Animal Ethical Committee, 36 animals were divided into six groups having six rats each: control, two weeks, one month, two months, four months and six months. Diabetes was induced with a single dose of streptozotocin administered through intraperitoneal route (60 mg/kg). Body weight and blood sugar were monitored at the biweekly interval. At the end of each experimental period, animals were euthanized by deep ether anesthesia and blood samples were collected by direct puncture of heart for biochemical analysis. Tissues were fixed in Karnovsky fixative and processed for paraffin sectioning. Routine and special stained sections were studied under the light microscope and relevant findings were recorded. RESULTS: Data obtained from biochemical analyses and histomorphometry along with the histopathological features revealed that with increasing duration of hyperglycemia was associated with increased serum creatinine and reduction in serum total protein; increased mean percentage of darkly stained large sized pituicytes and notable thickening of perisinusoidal collagen. CONCLUSION: It is therefore concluded that long-standing hyperglycemia which is associated with increased occurrence of predominantly large and darkly stained pituicytes and remarkably increased deposition of perisinusoidal collagen appear to be the important contributing factors somehow responsible for the derangement of the function of the posterior pituitary in chronic diabetes.","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85078594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/i6nns.0975.0223.10318.3
Arul Muthukumaraswamy, T. Arumugam
{"title":"Symptom Analysis and Surgical outcome of Supratentorial Meningioma: A Prospective Study","authors":"Arul Muthukumaraswamy, T. Arumugam","doi":"10.21088/i6nns.0975.0223.10318.3","DOIUrl":"https://doi.org/10.21088/i6nns.0975.0223.10318.3","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73635954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/IJNNS.0975.0223.10218.2
Baskar A.R, P. Shankar
{"title":"A Prospective Study of Endoscopic Third Ventriculostomy in Pediatric Andadult Hydrocephalus","authors":"Baskar A.R, P. Shankar","doi":"10.21088/IJNNS.0975.0223.10218.2","DOIUrl":"https://doi.org/10.21088/IJNNS.0975.0223.10218.2","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75898774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/I6NNS.0975.0223.10318.20
S. I. Khan, K. Ahsan, N. Ahmed, B. Chaurasia, D. Chowdhury
{"title":"Tuberculous Spondylitis of Craniovertebral Junction of a 70 Years Old Female: Case Report and Review of the Literature","authors":"S. I. Khan, K. Ahsan, N. Ahmed, B. Chaurasia, D. Chowdhury","doi":"10.21088/I6NNS.0975.0223.10318.20","DOIUrl":"https://doi.org/10.21088/I6NNS.0975.0223.10318.20","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81287276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/i6nns.0975.0223.10318.15
P. Viswajyothi, K. V. Kumar
{"title":"Utility of “International League against Epilepsy (ILAE)” Classification in Patients with Epilepsy","authors":"P. Viswajyothi, K. V. Kumar","doi":"10.21088/i6nns.0975.0223.10318.15","DOIUrl":"https://doi.org/10.21088/i6nns.0975.0223.10318.15","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85551562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/IJNNS.0975.0223.10218.6
Lakshman Rao Akyam, K. Ramaneshwar, Premjit Ray Mortha, B. Godugu, Abhishek Donthula
{"title":"Posterior Fossa Haematomas outcome Following Surgical Evacuation: A Prospective Study","authors":"Lakshman Rao Akyam, K. Ramaneshwar, Premjit Ray Mortha, B. Godugu, Abhishek Donthula","doi":"10.21088/IJNNS.0975.0223.10218.6","DOIUrl":"https://doi.org/10.21088/IJNNS.0975.0223.10218.6","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75666950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/I6NNS.0975.0223.10318.4
G. Sarma, A. Prabhu, Meghana Srinivas, T. Mathew, R. Nadig
{"title":"Restless Legs Syndrome as an Early Neurological Manifestation of Vitamin B12 Deficiency","authors":"G. Sarma, A. Prabhu, Meghana Srinivas, T. Mathew, R. Nadig","doi":"10.21088/I6NNS.0975.0223.10318.4","DOIUrl":"https://doi.org/10.21088/I6NNS.0975.0223.10318.4","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72647607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.15436/2377-1348.18.1934
V. Dalla, F. Antonaci, V. Rebecchi, G. Sances, P. Merlo, A. Giorgetti, F. D. Palma, E. Matta, C. Dallocchio, C. Tassorelli, A. Pezzini, G. Volta, Italia, Ommega Internationals
Received date: July 14, 2018 Accepted date: August 10, 2018 Published date: August 15, 2018 1 Headache Science Centre, Istituto Neurologico Nazionale Mondino, Pavia 2 UC Neurologia Speciale d’Urgenza, Istituto Neurologico Nazionale, Pavia 3 Dipartimento di Scienze del Sistema Nervoso e del Comportamento Università di Pavia 4 Centro Cefalee UOC Neurologia -VareseASST Settelaghi – Università dell’ Insubria 5 U.O.NeurologiaCentro Cefalee, Humanitas Gavazzeni, Bergamo 6 Centro Cefalee, Dipartimento di Neuroscienze H di Legnano ASST Ovest milanese 7 Centro Cefalee UOC Neurologia della ASST Lariana-Ospedale S. Anna di Como 8 Centro Cefalee UOC neurologia ASST Bergamo ovest 9 U O Neurologia, ASST Pavia, Ospedale Civile, Voghera 10 Dipartimento di Scienze Cliniche e Sperimentali, Clinica Neurologica, Università degli Studi di Brescia 11 Centro Cefalee U.O Neurologia Istituto Clinico Citta’ di Brescia, Brescia International Journal of Neurology and Brain Disorders
收到日期:7月14日，2018日接受日期:8月10日，2018日出版日期:奥古斯特15,2018年1 Headache科学中心、国家神经研究所Mondino、帕维亚2阿联酋全国紧急特别神经病学,神经学研究所,帕维亚3神经系统和行为科学系帕维亚大学神经学头痛UOC -VareseASST 4 Settelaghi—大学的Insubria 5 m . O . NeurologiaCentro头痛、管理Gavazzeni、贝加莫6头痛中心神经科学H米兰西工厂ASST 7系头痛UOC ASST神经病学中心Lariana-Ospedale S .安娜·科莫8头痛中心神经学UOC ASST贝尔加莫西9或神经,ASST帕维亚、民事医院、沃盖10临床和临床实验,神经科学系,universita degli Studi di布雷西亚11头痛中心阿拉伯联合酋长国或神经内科临床研究所城市布雷西亚,布雷西亚杂志》(International Journal of神经学和大脑,
{"title":"AURASTOP ® in the Treatment of Migraine Aura","authors":"V. Dalla, F. Antonaci, V. Rebecchi, G. Sances, P. Merlo, A. Giorgetti, F. D. Palma, E. Matta, C. Dallocchio, C. Tassorelli, A. Pezzini, G. Volta, Italia, Ommega Internationals","doi":"10.15436/2377-1348.18.1934","DOIUrl":"https://doi.org/10.15436/2377-1348.18.1934","url":null,"abstract":"Received date: July 14, 2018 Accepted date: August 10, 2018 Published date: August 15, 2018 1 Headache Science Centre, Istituto Neurologico Nazionale Mondino, Pavia 2 UC Neurologia Speciale d’Urgenza, Istituto Neurologico Nazionale, Pavia 3 Dipartimento di Scienze del Sistema Nervoso e del Comportamento Università di Pavia 4 Centro Cefalee UOC Neurologia -VareseASST Settelaghi – Università dell’ Insubria 5 U.O.NeurologiaCentro Cefalee, Humanitas Gavazzeni, Bergamo 6 Centro Cefalee, Dipartimento di Neuroscienze H di Legnano ASST Ovest milanese 7 Centro Cefalee UOC Neurologia della ASST Lariana-Ospedale S. Anna di Como 8 Centro Cefalee UOC neurologia ASST Bergamo ovest 9 U O Neurologia, ASST Pavia, Ospedale Civile, Voghera 10 Dipartimento di Scienze Cliniche e Sperimentali, Clinica Neurologica, Università degli Studi di Brescia 11 Centro Cefalee U.O Neurologia Istituto Clinico Citta’ di Brescia, Brescia International Journal of Neurology and Brain Disorders","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83375087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/ijnns.0975.0223.10218.4
R. Kalpana
{"title":"A Study on the Demographic Distribution of Epilepsy in a Tertiary Care Hospital","authors":"R. Kalpana","doi":"10.21088/ijnns.0975.0223.10218.4","DOIUrl":"https://doi.org/10.21088/ijnns.0975.0223.10218.4","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81205907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.21088/IJNNS.0975.0223.10318.16
K. Sudhakar, R. Manimaran, Dhanesh Kumar Kasinathan, B. Chaurasia, Pramati Technologies Chennai Tamil Nadu India. Data Scientist
{"title":"Incidence of Traumatically Induced Vertebral Artery Occlusion Associated with Cervical Spine Injuries: Prospective Study Using Magnetic Resonance Angiography","authors":"K. Sudhakar, R. Manimaran, Dhanesh Kumar Kasinathan, B. Chaurasia, Pramati Technologies Chennai Tamil Nadu India. Data Scientist","doi":"10.21088/IJNNS.0975.0223.10318.16","DOIUrl":"https://doi.org/10.21088/IJNNS.0975.0223.10318.16","url":null,"abstract":"","PeriodicalId":14163,"journal":{"name":"International journal of neurology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81193494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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