Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.154
S. Lee, B. Park, Chunsuk Kim
{"title":"Corrigendum: Methanol extracts of Asarum sieboldii Miq. induces apoptosis via the caspase pathway in human FaDu hypopharynx squamous carcinoma cells","authors":"S. Lee, B. Park, Chunsuk Kim","doi":"10.11620/ijob.2021.46.3.154","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.154","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84106264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.134
J. Y. Kang, Namju Kang, Yu-Mi Yang
Under physiological conditions, calcium (Ca 2+ ) regulates essential functions of polarized secretory cells by the stimulation of specific Ca 2+ signaling mechanisms, such as increases in intracellular Ca 2+ concentration ([Ca 2+ ] i ) via the store-operated Ca 2+ entry (SOCE) and the receptor-operated Ca 2+ entry (ROCE). Homer proteins are scaffold proteins that interact with G protein-coupled receptors, inositol 1,4,5-triphosphate (IP 3 ) receptors, Orai1-stromal interaction molecule 1, and transient receptor potential canonical (TRPC) channels. However, their role in the Ca 2+ signaling in exocrine cells remains unknown. In this study, we investigated the role of Homer2 in the Ca 2+ signaling and regulatory channels to mediate SOCE and ROCE in pancreatic acinar cells. Deletion of Homer2 (Homer2 –/– ) markedly increased the expression of TRPC3, TRPC6, and Orai1 in pancreatic acinar cells, whereas these expressions showed no difference in whole brains of wild-type and Homer2 –/– mice. Furthermore, the response of Ca 2+ entry by carbachol also showed significant changes to the patterns regulated by specific blockers of SOCE and ROCE in pancreatic acinar cells of Homer2 –/– mice. Thus, these results suggest that Homer2 plays a critical role in the regulatory action of the [Ca 2+ ] i via SOCE and ROCE in mouse pancreatic acinar cells.
{"title":"Regulation of the expression and function of TRPCs and Orai1 by Homer2 in mouse pancreatic acinar cells","authors":"J. Y. Kang, Namju Kang, Yu-Mi Yang","doi":"10.11620/ijob.2021.46.3.134","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.134","url":null,"abstract":"Under physiological conditions, calcium (Ca 2+ ) regulates essential functions of polarized secretory cells by the stimulation of specific Ca 2+ signaling mechanisms, such as increases in intracellular Ca 2+ concentration ([Ca 2+ ] i ) via the store-operated Ca 2+ entry (SOCE) and the receptor-operated Ca 2+ entry (ROCE). Homer proteins are scaffold proteins that interact with G protein-coupled receptors, inositol 1,4,5-triphosphate (IP 3 ) receptors, Orai1-stromal interaction molecule 1, and transient receptor potential canonical (TRPC) channels. However, their role in the Ca 2+ signaling in exocrine cells remains unknown. In this study, we investigated the role of Homer2 in the Ca 2+ signaling and regulatory channels to mediate SOCE and ROCE in pancreatic acinar cells. Deletion of Homer2 (Homer2 –/– ) markedly increased the expression of TRPC3, TRPC6, and Orai1 in pancreatic acinar cells, whereas these expressions showed no difference in whole brains of wild-type and Homer2 –/– mice. Furthermore, the response of Ca 2+ entry by carbachol also showed significant changes to the patterns regulated by specific blockers of SOCE and ROCE in pancreatic acinar cells of Homer2 –/– mice. Thus, these results suggest that Homer2 plays a critical role in the regulatory action of the [Ca 2+ ] i via SOCE and ROCE in mouse pancreatic acinar cells.","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79304575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.105
V. P. Dong, Ho-Gone Yoo
{"title":"Physicochemical properties of different phases of titanium dioxide nanoparticles","authors":"V. P. Dong, Ho-Gone Yoo","doi":"10.11620/ijob.2021.46.3.105","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.105","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"239 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73279139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.119
Hyemin Han, Y. Cho, Y. Bae
{"title":"Expression of vesicular glutamate transporter in transient receptor potential vanilloid 1-positive neurons in the rat trigeminal ganglion","authors":"Hyemin Han, Y. Cho, Y. Bae","doi":"10.11620/ijob.2021.46.3.119","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.119","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79092124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.127
Aeryun Kim, Ji-Hye Kim
{"title":"Role of γ-glutamyltranspeptidase in osteoclastogenesis induced by Fusobacterium nucleatum","authors":"Aeryun Kim, Ji-Hye Kim","doi":"10.11620/ijob.2021.46.3.127","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.127","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73980174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.99
So‐Hee Kim, Ji-Yeon Jung, Won-Jae Kim, Ok-Joon Kim, Young Kim, I. Kang
{"title":"Mechanisms of tissue factor induction by Porphyromonas gingivalis in human endothelial cells","authors":"So‐Hee Kim, Ji-Yeon Jung, Won-Jae Kim, Ok-Joon Kim, Young Kim, I. Kang","doi":"10.11620/ijob.2021.46.3.99","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.99","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79274490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-30DOI: 10.11620/ijob.2021.46.3.111
Sun‐Jin An, Jong-Uk Namkung, K. Ha, H. Jun, Hyun Young Kim, Bong‐Kyu Choi
{"title":"Inhibition of biofilm formation of periodontal pathogens by D-Arabinose","authors":"Sun‐Jin An, Jong-Uk Namkung, K. Ha, H. Jun, Hyun Young Kim, Bong‐Kyu Choi","doi":"10.11620/ijob.2021.46.3.111","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.3.111","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74936049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.11620/ijob.2021.46.2.74
Junyoung Jung, Joungmok Kim, J. Kim
{"title":"Autophagy: a lysosomal degradation process for cellular homeostasis and its relationship with oral squamous cell carcinoma","authors":"Junyoung Jung, Joungmok Kim, J. Kim","doi":"10.11620/ijob.2021.46.2.74","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.2.74","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80616368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-30DOI: 10.11620/ijob.2021.46.2.81
Kichul Kim, S. Roh
{"title":"Expression patterns of Rho-associated protein kinase signaling pathway-related genes in mouse submandibular glands","authors":"Kichul Kim, S. Roh","doi":"10.11620/ijob.2021.46.2.81","DOIUrl":"https://doi.org/10.11620/ijob.2021.46.2.81","url":null,"abstract":"","PeriodicalId":14180,"journal":{"name":"International Journal of Oral Biology","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73194117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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