Pub Date : 2023-08-31DOI: 10.1080/00914037.2023.2250051
T. Le, Thi Hong Chuong Nguyen, Thi Van Thi Tran, L. Lê, Xuân Anh Vũ Hồ, Thanh Minh Trần, Thuỳ Trang Lê, Hoang Luong Ngoc Nguyen, Minh Tuan Nguyen Dinh, Thi Hang Nga Phan, Thi Lan Huong Hoang, Chinh Chien Nguyen, Q. Le
{"title":"Quercetin-incorporated collagen/chitosan/SiO2 composite toward the robust antioxidant biomaterials","authors":"T. Le, Thi Hong Chuong Nguyen, Thi Van Thi Tran, L. Lê, Xuân Anh Vũ Hồ, Thanh Minh Trần, Thuỳ Trang Lê, Hoang Luong Ngoc Nguyen, Minh Tuan Nguyen Dinh, Thi Hang Nga Phan, Thi Lan Huong Hoang, Chinh Chien Nguyen, Q. Le","doi":"10.1080/00914037.2023.2250051","DOIUrl":"https://doi.org/10.1080/00914037.2023.2250051","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"2 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87815477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-26DOI: 10.1080/00914037.2023.2250046
Janhavi Bhavsar, P. Shende
{"title":"Nanocomplex of nisin with carbohydrate for the treatment of tuberculosis","authors":"Janhavi Bhavsar, P. Shende","doi":"10.1080/00914037.2023.2250046","DOIUrl":"https://doi.org/10.1080/00914037.2023.2250046","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"128 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73432601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.1080/00914037.2023.2250048
A. Özbal, Z. Dikmen, V. Bütün
Abstract Cross-linked and flexible poly(vinyl acetone ketal) (PV-A-K) films have been prepared as a result of ketalization reaction and monolith formation of poly(vinyl alcohol) (PVA), which has the feature of forming films quickly and is frequently used in biological fields. In this novel method, flexible PV-A-K films have been produced simply and in a short time accompanied by monolith formation without any catalyst in acetone. The effect of acetone ratio on the physical properties (i.e., swelling and mechanical properties) of such formations has been investigated to reveal significant influences of it. In addition, zinc oxide (ZnO) nanoparticles synthesized via the solvothermal method have been doped into PV-A-K films during film preparation. The prepared PV-A-K and ZnO doped PV-A-K films have been characterized with SEM, XRD, and FT-IR. Their mechanical properties have been investigated with a universal mechanical test machine. The acetone ratio is quite effective both on the porosity and stress/strain properties of the films. Antibacterial activities of the films are evaluated against four different strains (E. coli, S. aureus, P. aeruginosa, and E. faecalis) via the disk diffusion method. The films are selectively effective against S. aureus. These highly flexible and elastic films have great potential for biomedical applications, wound dressing, and antibacterial surface preparation. Graphical Abstract
{"title":"Preparation of elastic hydrogel films via in-situ ketalization of Poly(vinyl alcohol) and ZnO nanoparticle doped Poly(vinyl ketal) films as antibacterial surface","authors":"A. Özbal, Z. Dikmen, V. Bütün","doi":"10.1080/00914037.2023.2250048","DOIUrl":"https://doi.org/10.1080/00914037.2023.2250048","url":null,"abstract":"Abstract Cross-linked and flexible poly(vinyl acetone ketal) (PV-A-K) films have been prepared as a result of ketalization reaction and monolith formation of poly(vinyl alcohol) (PVA), which has the feature of forming films quickly and is frequently used in biological fields. In this novel method, flexible PV-A-K films have been produced simply and in a short time accompanied by monolith formation without any catalyst in acetone. The effect of acetone ratio on the physical properties (i.e., swelling and mechanical properties) of such formations has been investigated to reveal significant influences of it. In addition, zinc oxide (ZnO) nanoparticles synthesized via the solvothermal method have been doped into PV-A-K films during film preparation. The prepared PV-A-K and ZnO doped PV-A-K films have been characterized with SEM, XRD, and FT-IR. Their mechanical properties have been investigated with a universal mechanical test machine. The acetone ratio is quite effective both on the porosity and stress/strain properties of the films. Antibacterial activities of the films are evaluated against four different strains (E. coli, S. aureus, P. aeruginosa, and E. faecalis) via the disk diffusion method. The films are selectively effective against S. aureus. These highly flexible and elastic films have great potential for biomedical applications, wound dressing, and antibacterial surface preparation. Graphical Abstract","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"31 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83341227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.1080/00914037.2023.2250049
Qingyun Fu, Zhenzhao Guo, Bo Dongyin, H. Ke, Su Ziyu, Weihong Jin, Z. Yu, Shulan Xu, Li Hong
{"title":"Multi-drug delivery and osteogenic performance of β-tricalcium phosphate/alginate composite microspheres","authors":"Qingyun Fu, Zhenzhao Guo, Bo Dongyin, H. Ke, Su Ziyu, Weihong Jin, Z. Yu, Shulan Xu, Li Hong","doi":"10.1080/00914037.2023.2250049","DOIUrl":"https://doi.org/10.1080/00914037.2023.2250049","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"22 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74947599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-13DOI: 10.1080/00914037.2022.2066670
N. Bose, Kalaivizhi Rajappan, Gowriboy Natesan, S. Selvam
Abstract Thermoplastic polyurethane is known for its elasticity and hydrophobicity, which is significant for a few biomedical applications. The risk of clotting formation in blood-contacting devices is a major concern. Altering the surface of polymer with the addition of suitable nanofillers and additives can improve the blood compatibility of the prepared materials. Thus, aiming for enhanced blood compatibility of TPU (1) addition of PEG as an effective pore creator leads to enhancement in hydrophilicity, (2) modification of halloysite by universal bio-adhesives such as polydopamine, attach to the wall of HNTs by oxidation and self-polymerization, resulting as superior biomedical nanocomposites. The membrane is fabricated via the phase-inversion technique. TPU, TPU/PEG, and DHNTs@TPU/PEG were compared based on major characteristics such as hydrophilicity, pore analysis by SEM (ImageJ), and the blood compatibility test. In-Vitro blood coagulation and degradation study of pure TPU, TPU/PEG and DHNTs@TPU/PEG membrane suggest that the modified DHNTs-TPU/PEG membrane has better blood coagulation time and decreased hemolysis ratio. A degradation study with a variation in pH shows the breakage of a polymeric chain of the membrane. These results can suggest that the modified membrane has a potential application in the biomedical. Graphical Abstract
{"title":"DHNTs assimilated TPU/PEG membrane a new combination for evaluation of in-vitro blood-coagulation","authors":"N. Bose, Kalaivizhi Rajappan, Gowriboy Natesan, S. Selvam","doi":"10.1080/00914037.2022.2066670","DOIUrl":"https://doi.org/10.1080/00914037.2022.2066670","url":null,"abstract":"Abstract Thermoplastic polyurethane is known for its elasticity and hydrophobicity, which is significant for a few biomedical applications. The risk of clotting formation in blood-contacting devices is a major concern. Altering the surface of polymer with the addition of suitable nanofillers and additives can improve the blood compatibility of the prepared materials. Thus, aiming for enhanced blood compatibility of TPU (1) addition of PEG as an effective pore creator leads to enhancement in hydrophilicity, (2) modification of halloysite by universal bio-adhesives such as polydopamine, attach to the wall of HNTs by oxidation and self-polymerization, resulting as superior biomedical nanocomposites. The membrane is fabricated via the phase-inversion technique. TPU, TPU/PEG, and DHNTs@TPU/PEG were compared based on major characteristics such as hydrophilicity, pore analysis by SEM (ImageJ), and the blood compatibility test. In-Vitro blood coagulation and degradation study of pure TPU, TPU/PEG and DHNTs@TPU/PEG membrane suggest that the modified DHNTs-TPU/PEG membrane has better blood coagulation time and decreased hemolysis ratio. A degradation study with a variation in pH shows the breakage of a polymeric chain of the membrane. These results can suggest that the modified membrane has a potential application in the biomedical. Graphical Abstract","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"23 1","pages":"925 - 936"},"PeriodicalIF":3.2,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75499726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-10DOI: 10.1080/00914037.2023.2243370
Najmeh Kalbali, S. Hashemi-Najafabadi, F. Bagheri
{"title":"Improving pore size of electrospun gelatin scaffolds containing graphene oxide using PEG as a sacrificial agent for bone tissue engineering","authors":"Najmeh Kalbali, S. Hashemi-Najafabadi, F. Bagheri","doi":"10.1080/00914037.2023.2243370","DOIUrl":"https://doi.org/10.1080/00914037.2023.2243370","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"156 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79881794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-10DOI: 10.1080/00914037.2023.2243368
Shivam Nishad, R. Mazumder, Swarupanjali Padhi, Malakapogu Ravindra Basu, P. Pandey
{"title":"Enhancement of bioavailability of therapeutics using drug conjugation approach: an in-depth review","authors":"Shivam Nishad, R. Mazumder, Swarupanjali Padhi, Malakapogu Ravindra Basu, P. Pandey","doi":"10.1080/00914037.2023.2243368","DOIUrl":"https://doi.org/10.1080/00914037.2023.2243368","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"29 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90475866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-10DOI: 10.1080/00914037.2023.2243363
Cristhian Pinto, Leidi Méndez, Bernardo Camacho-Rodríguez, Ingrid Silva-Cote
{"title":"Antibacterial PVA/Chitosan/alginate/Meropenem-based hydrogel as a potential therapeutic strategy for chronic ulcers infections","authors":"Cristhian Pinto, Leidi Méndez, Bernardo Camacho-Rodríguez, Ingrid Silva-Cote","doi":"10.1080/00914037.2023.2243363","DOIUrl":"https://doi.org/10.1080/00914037.2023.2243363","url":null,"abstract":"","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"39 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78371718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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