Pub Date : 2024-07-06DOI: 10.18203/2320-6012.ijrms20241949
Abhishek Kumar Singh, S. M. Doddagowda
Background: Cervical cancer is a common gynecological malignancy and public health problem that can be prevented, but the utilization of screening is just 2.6%-5% in India. Healthcare providers mainly nursing personnel are crucial and play a vital role in raising awareness and educating the public about implementation of low-cost cervical cancer screening approaches in low-resource settings. Objectives were to determine baseline information about knowledge of cervical cancer and explore attitude and practice of pap smear screening among staff nurses. Methods: The questionnaire containing mostly recognition and some recall type questions about demographics, knowledge about cervical cancer, its risk factors, screening techniques, attitudes towards cervical cancer screening and its practices and their knowledge was tested. Results: Analyses of knowledge showed that majority of nurses recognized the risk factors and symptoms associated with carcinoma of cervix. A considerable lack of knowledge was observed on the treatment of cervical cancer but a significant portion of nurses knew about prevention. A positive attitude was observed on all aspects of cervical cancer and its prevention. Conclusions: This study demonstrates a good knowledge and positive attitude about carcinoma of cervix and its prevention amongst the nurses which plays a key role in the campaign to prevent cervical malignancy. Poor practice seen in this study emphasizes the need to translate the awareness to practice. Easier availability of HPV testing and better distribution of HPV vaccine is paramount to successfully prevent cervical cancer in future.
{"title":"Awareness and knowledge about cervical cancer and pap test among nursing staff at a rural tertiary care hospital","authors":"Abhishek Kumar Singh, S. M. Doddagowda","doi":"10.18203/2320-6012.ijrms20241949","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241949","url":null,"abstract":"Background: Cervical cancer is a common gynecological malignancy and public health problem that can be prevented, but the utilization of screening is just 2.6%-5% in India. Healthcare providers mainly nursing personnel are crucial and play a vital role in raising awareness and educating the public about implementation of low-cost cervical cancer screening approaches in low-resource settings. Objectives were to determine baseline information about knowledge of cervical cancer and explore attitude and practice of pap smear screening among staff nurses.\u0000Methods: The questionnaire containing mostly recognition and some recall type questions about demographics, knowledge about cervical cancer, its risk factors, screening techniques, attitudes towards cervical cancer screening and its practices and their knowledge was tested.\u0000Results: Analyses of knowledge showed that majority of nurses recognized the risk factors and symptoms associated with carcinoma of cervix. A considerable lack of knowledge was observed on the treatment of cervical cancer but a significant portion of nurses knew about prevention. A positive attitude was observed on all aspects of cervical cancer and its prevention.\u0000Conclusions: This study demonstrates a good knowledge and positive attitude about carcinoma of cervix and its prevention amongst the nurses which plays a key role in the campaign to prevent cervical malignancy. Poor practice seen in this study emphasizes the need to translate the awareness to practice. Easier availability of HPV testing and better distribution of HPV vaccine is paramount to successfully prevent cervical cancer in future.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141671518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-14DOI: 10.18203/2320-6012.ijrms20241616
Nagesh S. Nagapurkar, Viquar A. Patel
Background: The aim of our study is to evaluate the outcome of medical expulsion therapy (MET) for lower ureteric calculi and asses the clinical, laboratory and radiological factors that predict conservative approach. We evaluated the efficacy of combined drug therapy with alpha 1 adrenergic receptor antagonist tamsulosin and corticosteroid deflazacort for MET therapy for lower ureteric calculi. Methods: A prospective randomized control study was conducted in the department of surgery urology wing on out patients (OPD) basis at IIMSR Medical College Warudi District Jalna a tertiary referral center after approval from the ethical committee. The study conducted between 01 January 2020 to 31 December 2023 over period of three years. Total 76 cases included with the age 18 years old and above. The patients were examined weekly with ultrasonography and kidney ureter bladder (KUB) for 4 weeks and the stone expulsion rate and time, pain episodes during follow-up period, total diclofenac dosage and the need for any intervention was noted close monitoring and timely follow up is mandatory counselling and selection of patient is key factor. Results: Stone expulsion with patients on MET was 84% which is higher as compare to another group 57%. Conclusions: Medical therapy with a combination of α-adrenergic blocker and corticosteroid is associated with good stone expulsion rates and should be considered in all patients with lower ureteral stones of size less than 10 mm who are not having any contraindications for medical therapy provided close monitoring and timely follow up is mandatory counselling and selection of patient is key factor.
{"title":"A study of predicting factors and medical expulsion therapy for solitory lower ureteric calculi","authors":"Nagesh S. Nagapurkar, Viquar A. Patel","doi":"10.18203/2320-6012.ijrms20241616","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241616","url":null,"abstract":"Background: The aim of our study is to evaluate the outcome of medical expulsion therapy (MET) for lower ureteric calculi and asses the clinical, laboratory and radiological factors that predict conservative approach. We evaluated the efficacy of combined drug therapy with alpha 1 adrenergic receptor antagonist tamsulosin and corticosteroid deflazacort for MET therapy for lower ureteric calculi.\u0000Methods: A prospective randomized control study was conducted in the department of surgery urology wing on out patients (OPD) basis at IIMSR Medical College Warudi District Jalna a tertiary referral center after approval from the ethical committee. The study conducted between 01 January 2020 to 31 December 2023 over period of three years. Total 76 cases included with the age 18 years old and above. The patients were examined weekly with ultrasonography and kidney ureter bladder (KUB) for 4 weeks and the stone expulsion rate and time, pain episodes during follow-up period, total diclofenac dosage and the need for any intervention was noted close monitoring and timely follow up is mandatory counselling and selection of patient is key factor.\u0000Results: Stone expulsion with patients on MET was 84% which is higher as compare to another group 57%.\u0000Conclusions: Medical therapy with a combination of α-adrenergic blocker and corticosteroid is associated with good stone expulsion rates and should be considered in all patients with lower ureteral stones of size less than 10 mm who are not having any contraindications for medical therapy provided close monitoring and timely follow up is mandatory counselling and selection of patient is key factor.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"48 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141339628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-12DOI: 10.18203/2320-6012.ijrms20241612
Jazmin V. Sanchez, Rene R. Guerrero, Karla F. G. G. Rubio, Noe I. G. Mancilla, Raymundo T. Piña
Background: Breast reconstruction with latissimus dorsi muscle transfer is one of the most frequent procedures at our hospital. The objective is to evaluate if there is any functional impairment after the surgery with a potential impact of patient´s daily life. Methods: Functional morbidity was analyzed applying the disabilities of the arm, shoulder and hand (DASH) questionnaire and shoulder range of motion with goniometer in 42 patients whose breast reconstruction was between 2016 and 2022 at our hospital. We collected data using Microsoft excel V16.47.1 and analyzed data with statistical package for the social sciences (SPSS) software, v23.0. Results: There was statistically significant difference for disability/symptom DASH score in cases of bilateral reconstruction and for cases undergoing a procedure on the right side versus left side. Conclusions: In patients with bilateral breast reconstruction, we found a greater DASH score in dysfunction and symptoms which associates with poor quality of life, as well as when the flap is on the contralateral extremity of the hand dominance; in those cases, there are other reconstructive procedures that provide greater safety and less disability to the patient. For evaluating extension, we need more prospective and comparative studies with strict follow up of the patients and same series of rehabilitation.
背景:背阔肌移植乳房再造术是我院最常见的手术之一。我们的目的是评估术后是否存在功能障碍,以及对患者日常生活的潜在影响:方法:采用手臂、肩部和手部残疾(DASH)调查问卷和肩部活动范围量角器,对我院在2016年至2022年期间进行乳房重建的42名患者的功能性发病率进行分析。我们使用 Microsoft excel V16.47.1 收集数据,并使用社会科学统计软件包(SPSS)v23.0 分析数据:双侧乳房再造患者的残疾/症状DASH评分,以及右侧与左侧乳房再造患者的残疾/症状DASH评分在统计学上存在显著差异:在双侧乳房重建患者中,我们发现功能障碍和症状的 DASH 评分更高,这与生活质量低下有关,而且当皮瓣位于手部优势的对侧肢体时也是如此;在这些情况下,有其他重建手术可以为患者提供更高的安全性和更少的残疾。为了评估延伸效果,我们需要进行更多的前瞻性比较研究,对患者进行严格的随访和同一系列的康复治疗。
{"title":"Disability evaluation after latissimus dorsi muscle transfer in breast reconstruction using DASH score","authors":"Jazmin V. Sanchez, Rene R. Guerrero, Karla F. G. G. Rubio, Noe I. G. Mancilla, Raymundo T. Piña","doi":"10.18203/2320-6012.ijrms20241612","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241612","url":null,"abstract":"Background: Breast reconstruction with latissimus dorsi muscle transfer is one of the most frequent procedures at our hospital. The objective is to evaluate if there is any functional impairment after the surgery with a potential impact of patient´s daily life.\u0000Methods: Functional morbidity was analyzed applying the disabilities of the arm, shoulder and hand (DASH) questionnaire and shoulder range of motion with goniometer in 42 patients whose breast reconstruction was between 2016 and 2022 at our hospital. We collected data using Microsoft excel V16.47.1 and analyzed data with statistical package for the social sciences (SPSS) software, v23.0.\u0000Results: There was statistically significant difference for disability/symptom DASH score in cases of bilateral reconstruction and for cases undergoing a procedure on the right side versus left side.\u0000Conclusions: In patients with bilateral breast reconstruction, we found a greater DASH score in dysfunction and symptoms which associates with poor quality of life, as well as when the flap is on the contralateral extremity of the hand dominance; in those cases, there are other reconstructive procedures that provide greater safety and less disability to the patient. For evaluating extension, we need more prospective and comparative studies with strict follow up of the patients and same series of rehabilitation.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"103 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141352323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-07DOI: 10.18203/2320-6012.ijrms20241608
Made Yudha Ganesa Wikantyas Widia, I. Budiana, I. N. B. Mahendra, I. N. H. Sanjaya, Anom Suardika, I. G. S. Winata
Background: Ovarian cancer is one of the top three most common cancers in women. Most are detected at an advanced stage, so early detection is essential. A scoring system can easily predict an ovarian malignancy. IOTA Simple Rules and RMI-4 are easy-to-implement scoring systems. This study aimed to evaluate the comparison between the accuracy of the IOTA simple rules scoring system and RMI-4 as a predictor of malignancy in ovarian tumor cases at Prof. Dr. IGNG Ngoerah general hospital. Methods: This study used a diagnostic trial design involving 120 ovarian tumor patients undergoing surgery at Prof. Dr. IGNG Ngoerah general hospital, with 100 patients meeting the inclusion criteria. The collected data were tabulated and analyzed using SPSS for Windows ver. 22. Results were considered significant if p≤0.05. Results: From 100 patient samples who met the inclusion criteria, 60 subjects (60%) were ovarian tumors with benign histopathologic results, and 40 (40%) subjects were tumors with malignant histopathology. The majority of ovarian tumors with malignant histopathology were found in the age group >50 years (52.5%), the menopausal group (57.5%), and multiparity (70%). CA-125 levels above 35 U/ml are found in 90% of the population, with details of 92.5% found in populations with malignant histopathological tumors. The AUC values for RMI-4 and IOTA simple rules are 0.846 and 0.925, with the p value for each scoring system being <0.001. Conclusions: This study found that the IOTA simple rules scoring method has a better diagnostic value than RMI-4 scoring.
{"title":"Comparison of the international ovarian tumor analysis simple rules scoring system and risk of malignancy index-4 as predictors of ovarian malignancy","authors":"Made Yudha Ganesa Wikantyas Widia, I. Budiana, I. N. B. Mahendra, I. N. H. Sanjaya, Anom Suardika, I. G. S. Winata","doi":"10.18203/2320-6012.ijrms20241608","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241608","url":null,"abstract":"Background: Ovarian cancer is one of the top three most common cancers in women. Most are detected at an advanced stage, so early detection is essential. A scoring system can easily predict an ovarian malignancy. IOTA Simple Rules and RMI-4 are easy-to-implement scoring systems. This study aimed to evaluate the comparison between the accuracy of the IOTA simple rules scoring system and RMI-4 as a predictor of malignancy in ovarian tumor cases at Prof. Dr. IGNG Ngoerah general hospital.\u0000Methods: This study used a diagnostic trial design involving 120 ovarian tumor patients undergoing surgery at Prof. Dr. IGNG Ngoerah general hospital, with 100 patients meeting the inclusion criteria. The collected data were tabulated and analyzed using SPSS for Windows ver. 22. Results were considered significant if p≤0.05.\u0000Results: From 100 patient samples who met the inclusion criteria, 60 subjects (60%) were ovarian tumors with benign histopathologic results, and 40 (40%) subjects were tumors with malignant histopathology. The majority of ovarian tumors with malignant histopathology were found in the age group >50 years (52.5%), the menopausal group (57.5%), and multiparity (70%). CA-125 levels above 35 U/ml are found in 90% of the population, with details of 92.5% found in populations with malignant histopathological tumors. The AUC values for RMI-4 and IOTA simple rules are 0.846 and 0.925, with the p value for each scoring system being <0.001.\u0000Conclusions: This study found that the IOTA simple rules scoring method has a better diagnostic value than RMI-4 scoring.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":" 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141374614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-07DOI: 10.18203/2320-6012.ijrms20241609
Rashmi Gupta Bajpai, Ayush Garg
Acute febrile illnesses with systemic involvement can present significant diagnostic and therapeutic challenges, particularly in patients with multiple comorbidities. This case report highlights a complex presentation of acute febrile illness with pancytopenia and immune-mediated cutaneous vasculitis in a patient with type II diabetes mellitus. A 52-year-old male with a known history of type II diabetes mellitus presented with fever, decreased oral intake, loose stools, oral ulcers, dysphagia, and rashes over the trunk and abdomen for four days. Upon admission to the ICU, extensive diagnostic evaluations were performed, revealing significant hematological, biochemical, and serological abnormalities. Imaging studies and histopathological examinations were conducted to further investigate the underlying etiology. Laboratory findings indicated pancytopenia, acute kidney injury, and hyperkalemia. Infectious disease workup was largely negative, except for a positive CMV IgG. Imaging studies revealed medical renal disease, and a skin punch biopsy confirmed cutaneous leukocytoclastic vasculitis. Bone marrow biopsy suggested bone marrow suppression. Multidisciplinary management, including dialysis, IV fluids, antibiotics, blood transfusions, steroids, and Ganciclovir, led to the patient’s gradual improvement and stabilization. The comprehensive diagnostic and therapeutic approach in this case underscores the importance of considering immune-mediated etiologies in patients with atypical presentations. Multidisciplinary collaboration was crucial in managing the multifaceted clinical condition of the patient. Early recognition and prompt multidisciplinary management are essential in similar cases. Extensive diagnostic evaluations should be performed to identify the underlying causes, and immune-mediated etiologies should be considered in complex presentations. Further research is recommended to explore optimal management strategies for such multifaceted conditions.
全身受累的急性发热性疾病会给诊断和治疗带来巨大挑战,尤其是对于患有多种并发症的患者。本病例报告重点介绍了一名 II 型糖尿病患者急性发热伴泛发性皮肤炎和免疫介导的皮肤血管炎的复杂表现。一名 52 岁的男性患者已知有 II 型糖尿病病史,表现为发热、进食减少、大便稀烂、口腔溃疡、吞咽困难以及躯干和腹部皮疹,已持续四天。入住重症监护室后,医生对其进行了广泛的诊断评估,发现其血液学、生化和血清学均有明显异常。为了进一步查明病因,对患者进行了影像学检查和组织病理学检查。实验室检查结果显示,患者出现全血细胞减少、急性肾损伤和高钾血症。除了 CMV IgG 阳性外,传染病检查结果基本为阴性。影像学检查发现了内科肾病,皮肤穿刺活检证实了皮肤白细胞坏死性血管炎。骨髓活检显示骨髓抑制。多学科治疗,包括透析、静脉输液、抗生素、输血、类固醇和更昔洛韦,使患者病情逐渐好转并趋于稳定。该病例的综合诊断和治疗方法强调了考虑非典型表现患者的免疫介导病因的重要性。多学科协作对于处理患者多方面的临床状况至关重要。在类似病例中,早期识别和及时的多学科管理至关重要。应进行广泛的诊断评估以确定潜在的病因,对于复杂的病例应考虑免疫介导的病因。建议进一步开展研究,探索针对此类多方面病症的最佳治疗策略。
{"title":"Rare case of immune mediated cutaneous leucoclastic vasculitis with pancytopenia in a rheumatoid arthritis patient with chronic cytomegalovirus infection","authors":"Rashmi Gupta Bajpai, Ayush Garg","doi":"10.18203/2320-6012.ijrms20241609","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241609","url":null,"abstract":"Acute febrile illnesses with systemic involvement can present significant diagnostic and therapeutic challenges, particularly in patients with multiple comorbidities. This case report highlights a complex presentation of acute febrile illness with pancytopenia and immune-mediated cutaneous vasculitis in a patient with type II diabetes mellitus. A 52-year-old male with a known history of type II diabetes mellitus presented with fever, decreased oral intake, loose stools, oral ulcers, dysphagia, and rashes over the trunk and abdomen for four days. Upon admission to the ICU, extensive diagnostic evaluations were performed, revealing significant hematological, biochemical, and serological abnormalities. Imaging studies and histopathological examinations were conducted to further investigate the underlying etiology. Laboratory findings indicated pancytopenia, acute kidney injury, and hyperkalemia. Infectious disease workup was largely negative, except for a positive CMV IgG. Imaging studies revealed medical renal disease, and a skin punch biopsy confirmed cutaneous leukocytoclastic vasculitis. Bone marrow biopsy suggested bone marrow suppression. Multidisciplinary management, including dialysis, IV fluids, antibiotics, blood transfusions, steroids, and Ganciclovir, led to the patient’s gradual improvement and stabilization. The comprehensive diagnostic and therapeutic approach in this case underscores the importance of considering immune-mediated etiologies in patients with atypical presentations. Multidisciplinary collaboration was crucial in managing the multifaceted clinical condition of the patient. Early recognition and prompt multidisciplinary management are essential in similar cases. Extensive diagnostic evaluations should be performed to identify the underlying causes, and immune-mediated etiologies should be considered in complex presentations. Further research is recommended to explore optimal management strategies for such multifaceted conditions.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141371480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-06DOI: 10.18203/2320-6012.ijrms20241604
M. D. Gaikwad, Bibi Zainab, Amir Choudhary
Cervicofacial actinomycosis is an uncommon disease caused by Actinomycosis israelii. Chronic ‘sialadenitis’ of parotid gland is an insidious inflammatory disorder and may form a fibrous mass. We report a case of 55 years old female presenting with mass in right parotid region-on imaging-malignant neoplasm of parotid gland. But on histopathology-actinomycosis and chronic parotid sialadenitis.
{"title":"Cervicofacial actinomycosis with chronic parotid sialadenitis-mimicking malignant neoplasm of parotid gland: a rare case","authors":"M. D. Gaikwad, Bibi Zainab, Amir Choudhary","doi":"10.18203/2320-6012.ijrms20241604","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20241604","url":null,"abstract":"Cervicofacial actinomycosis is an uncommon disease caused by Actinomycosis israelii. Chronic ‘sialadenitis’ of parotid gland is an insidious inflammatory disorder and may form a fibrous mass. We report a case of 55 years old female presenting with mass in right parotid region-on imaging-malignant neoplasm of parotid gland. But on histopathology-actinomycosis and chronic parotid sialadenitis.\u0000 ","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"9 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141378637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-06DOI: 10.18203/2320-6012.ijrms20241602
Wijaya Kusuma, Ardi Andriatno, Budhi Hami Seno
Background: Lung cancer patients are at high risk for depression, which is associated with poor treatment adherence. Medical hypnosis can improve symptoms of depression and affect interleukin-6 levels. This study aims to determine the effectiveness of medical hypnosis in improving depression and reducing IL-6 levels in lung cancer patients. Methods: This study is a quasi-experimental study with a pretest and post-test control group design. It assessed depressive symptoms using BDI-II scores and serum IL-6 levels in an intervention group receiving medical hypnosis and standard therapy compared to a control group receiving standard therapy. Data analysis was conducted using univariate tests, followed by Pearson correlation tests and effect size measurement with Cohen's d test. Results: The Wilcoxon test showed a decrease in IL-6 levels in the intervention group by 14.66±19.45 (p=0.008) and a reduction in BDI-II scores by 8.26±4.78 (p=0.001). Correlation tests indicated a significant relationship between IL-6 levels and BDI-II scores (r=0.472; p=0.009). Cohen's d test showed the effect size of medical hypnosis on IL-6 levels was 0.754 (moderate=0.5