首页 > 最新文献

International Journal of Research in Medical Sciences最新文献

英文 中文
Qatar National Diabetes Strategy for the growing diabetes pandemic (2016-2022) - are we there yet? 针对日益严重的糖尿病大流行的卡塔尔国家糖尿病战略(2016-2022 年)--我们到了吗?
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240871
Benazir Shah
Diabetes Mellitus (DM) is increasingly recognized as a major public health challenge with 422 million people suffering worldwide in 2014. Awad et al anticipated that by 2050, that DM prevalence and incidence in Qatar will rise significantly, emphasizing the rapidly expanding need for health care resources to treat the condition and highlighting the necessity of intervention techniques for treatment and prevention that are specific for each nationality in Qatar.
糖尿病(DM)日益被视为一项重大的公共卫生挑战,2014 年全球有 4.22 亿人患有糖尿病。Awad 等人预计,到 2050 年,卡塔尔的糖尿病流行率和发病率将大幅上升,这强调了治疗糖尿病的医疗资源需求迅速扩大,并突出了针对卡塔尔各民族的治疗和预防干预技术的必要性。
{"title":"Qatar National Diabetes Strategy for the growing diabetes pandemic (2016-2022) - are we there yet?","authors":"Benazir Shah","doi":"10.18203/2320-6012.ijrms20240871","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240871","url":null,"abstract":"Diabetes Mellitus (DM) is increasingly recognized as a major public health challenge with 422 million people suffering worldwide in 2014. Awad et al anticipated that by 2050, that DM prevalence and incidence in Qatar will rise significantly, emphasizing the rapidly expanding need for health care resources to treat the condition and highlighting the necessity of intervention techniques for treatment and prevention that are specific for each nationality in Qatar.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140367600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower urinary tract symptoms evaluation with uroflowmetry in patients with benign prostatic hyperplasia 用尿流率测量法评估良性前列腺增生患者的下尿路症状
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240839
Shivendra Agrawal, Srinath N., Prathvi, Sreedhar Reddy, Raju L. N., Deepak Bolbandi
Background: Uroflowmetry, a non-invasive urodynamic technique, is commonly employed in evaluating patients with potential lower urinary tract dysfunction. Accurate assessment of the severity of lower urinary tract symptoms (LUTS) can be achieved through the utilization of various validated questionnaires, such as the International Prostate Symptom Score (IPSS). The objective of this study was to investigate the correlation between uroflowmetry parameters and the severity of symptoms.Methods: Fifty patients with LUTS caused by benign prostatic hyperplasia were evaluated by using uroflowmetry, IPSS, prostate volume estimation from May 2022 to December 2023. The correlations between these parameters were quantified by means of Spearman correlation co-efficients.Results: Significant statistical correlations were identified between the IPSS and uroflowmetry outcomes, including peak flow rate, average flow rate, and post-void residual urine. However, no correlation was observed between the IPSS and measurements of prostate volume.Conclusions: A positive correlation was observed between the measured peak flow rate through uroflowmetry and the severity of lower urinary tract symptoms.
背景:尿流率测定法是一种无创尿动力学技术,通常用于评估潜在的下尿路功能障碍患者。通过使用各种有效问卷,如国际前列腺症状评分(IPSS),可以准确评估下尿路症状(LUTS)的严重程度。本研究旨在探讨尿流率参数与症状严重程度之间的相关性:方法:从2022年5月至2023年12月,采用尿流率测量法、IPSS和前列腺体积估算法对50名良性前列腺增生引起的LUTS患者进行了评估。这些参数之间的相关性通过斯皮尔曼相关系数进行量化:结果:IPSS与尿流测定结果(包括峰值流速、平均流速和排尿后残余尿)之间存在显著的统计学相关性。然而,在 IPSS 和前列腺体积测量值之间没有观察到相关性:结论:通过尿流率测量法测得的峰值尿流率与下尿路症状的严重程度呈正相关。
{"title":"Lower urinary tract symptoms evaluation with uroflowmetry in patients with benign prostatic hyperplasia","authors":"Shivendra Agrawal, Srinath N., Prathvi, Sreedhar Reddy, Raju L. N., Deepak Bolbandi","doi":"10.18203/2320-6012.ijrms20240839","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240839","url":null,"abstract":"Background: Uroflowmetry, a non-invasive urodynamic technique, is commonly employed in evaluating patients with potential lower urinary tract dysfunction. Accurate assessment of the severity of lower urinary tract symptoms (LUTS) can be achieved through the utilization of various validated questionnaires, such as the International Prostate Symptom Score (IPSS). The objective of this study was to investigate the correlation between uroflowmetry parameters and the severity of symptoms.\u0000Methods: Fifty patients with LUTS caused by benign prostatic hyperplasia were evaluated by using uroflowmetry, IPSS, prostate volume estimation from May 2022 to December 2023. The correlations between these parameters were quantified by means of Spearman correlation co-efficients.\u0000Results: Significant statistical correlations were identified between the IPSS and uroflowmetry outcomes, including peak flow rate, average flow rate, and post-void residual urine. However, no correlation was observed between the IPSS and measurements of prostate volume.\u0000Conclusions: A positive correlation was observed between the measured peak flow rate through uroflowmetry and the severity of lower urinary tract symptoms.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"51 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140367876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastric outlet obstruction secondary to adult hypertrophic pyloric stenosis: case report and literature review 继发于成人肥厚性幽门狭窄的胃出口梗阻:病例报告和文献综述
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240854
Citlali Calderón, Steve Belmont
Adult hypertrophic pyloric stenosis is a rare entity; the most common type is secondary to underlying gastrointestinal pathologies, such as peptic ulcer, malignant tumors, and certain inflammatory diseases. A rare case of hypertrophic pyloric stenosis is presented in an adult patient secondary to acid peptic disease, presenting with gastric outlet obstruction, treated in the first instance with pyloric dilation successfully, however, the clinical picture has recurred now with 90% hypertrophic pyloric stenosis, it was decided to perform a surgical procedure with roux-en-Y gastrojejunal diversion, progressing with adequate evolution. There is no consensus on which is the most effective treatment. However, most authors seem to favor gastric resection due to the risk of malignancy secondary to long-standing hypertrophic pyloric stenosis.
成人肥厚性幽门狭窄是一种罕见病;最常见的类型是继发于消化性溃疡、恶性肿瘤和某些炎症等潜在胃肠道病变。本病例是一例罕见的肥厚性幽门狭窄病例,患者为成人,继发于胃酸过多性疾病,表现为胃出口梗阻,最初采用幽门扩张术治疗成功,但现在临床症状复发,肥厚性幽门狭窄达90%,因此决定采用roux-en-Y胃空肠转流手术,手术进展顺利。关于哪种治疗方法最有效,目前还没有达成共识。不过,由于长期肥厚性幽门狭窄有继发恶性肿瘤的风险,大多数学者似乎更倾向于胃切除术。
{"title":"Gastric outlet obstruction secondary to adult hypertrophic pyloric stenosis: case report and literature review","authors":"Citlali Calderón, Steve Belmont","doi":"10.18203/2320-6012.ijrms20240854","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240854","url":null,"abstract":"Adult hypertrophic pyloric stenosis is a rare entity; the most common type is secondary to underlying gastrointestinal pathologies, such as peptic ulcer, malignant tumors, and certain inflammatory diseases. A rare case of hypertrophic pyloric stenosis is presented in an adult patient secondary to acid peptic disease, presenting with gastric outlet obstruction, treated in the first instance with pyloric dilation successfully, however, the clinical picture has recurred now with 90% hypertrophic pyloric stenosis, it was decided to perform a surgical procedure with roux-en-Y gastrojejunal diversion, progressing with adequate evolution. There is no consensus on which is the most effective treatment. However, most authors seem to favor gastric resection due to the risk of malignancy secondary to long-standing hypertrophic pyloric stenosis.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"47 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Observation of cardiac profile among the adult population of Sreemangal 观察斯雷芒加尔成人的心脏概况
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240828
M. Nazem Al Qureshi, A. H. M. Anisuzzaman, Niloy Chandra Das, Arpita Roy, Abdullah Al Mamun, M. Anwarul Amin, M. Hasan Ali, Dihan Tahite
Background: Cardiovascular diseases are a leading cause of morbidity and mortality worldwide. The prevalence and risk factors of CVDs vary across different populations and regions. This study aimed to observe the cardiac profile among the adult population of Sreemangal, Bangladesh, to identify the prevalence and risk factors of CVDs in this population.Methods: This prospective observational study was conducted over a six-month period at a public health camp in Sreemangal, Bangladesh. A total of 137 adult participants were purposively selected. Data were collected through a structured questionnaire and physical examination, including measurements of blood pressure and laboratory analysis of blood samples.Results: The study found that 44.53% of participants had elevated blood pressure, and 21.90% had stage 1 hypertension. Interestingly, 36.50% of participants were unaware of their hypertension status. Furthermore, 26.28% of participants had a known history of diabetes, but blood glucose level analysis revealed an additional 14.85% of participants were prediabetic, and 6.93% were diabetic based on fasting blood glucose levels. A statistically significant association was found between increasing age and the stage of hypertension (p<0.001), and between fasting and normal blood glucose levels and the stage of hypertension (p<0.005 and p<0.05, respectively).Conclusions: The findings of this study underscore the need for targeted interventions to prevent and manage CVDs in the adult population of Sreemangal, Bangladesh. These interventions should include regular screening for CVD risk factors, health education to increase awareness of these risk factors, and strategies to promote healthy lifestyle behaviors.
背景:心血管疾病是全球发病和死亡的主要原因。不同人群和地区的心血管疾病患病率和风险因素各不相同。本研究旨在观察孟加拉国斯雷芒加尔(Sreemangal)成年人群的心脏概况,以确定该人群心血管疾病的患病率和风险因素:这项前瞻性观察研究在孟加拉国 Sreemangal 的一个公共卫生营地进行,为期六个月。研究有目的性地选择了 137 名成年参与者。通过结构化问卷和身体检查收集数据,包括测量血压和对血液样本进行实验室分析:研究发现,44.53% 的参与者血压升高,21.90% 的参与者为一期高血压。有趣的是,36.50% 的参与者不知道自己患有高血压。此外,26.28% 的参与者已知有糖尿病史,但血糖水平分析显示,另有 14.85% 的参与者为糖尿病前期,6.93% 的参与者根据空腹血糖水平患有糖尿病。研究发现,年龄增长与高血压分期之间有统计学意义(p<0.001),空腹血糖水平和正常血糖水平与高血压分期之间有统计学意义(分别为 p<0.005 和 p<0.05):这项研究的结果表明,有必要采取有针对性的干预措施,预防和控制孟加拉国斯雷芒加尔成人的心血管疾病。这些干预措施应包括定期筛查心血管疾病的风险因素、开展健康教育以提高人们对这些风险因素的认识,以及推广健康生活方式行为的策略。
{"title":"Observation of cardiac profile among the adult population of Sreemangal","authors":"M. Nazem Al Qureshi, A. H. M. Anisuzzaman, Niloy Chandra Das, Arpita Roy, Abdullah Al Mamun, M. Anwarul Amin, M. Hasan Ali, Dihan Tahite","doi":"10.18203/2320-6012.ijrms20240828","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240828","url":null,"abstract":"Background: Cardiovascular diseases are a leading cause of morbidity and mortality worldwide. The prevalence and risk factors of CVDs vary across different populations and regions. This study aimed to observe the cardiac profile among the adult population of Sreemangal, Bangladesh, to identify the prevalence and risk factors of CVDs in this population.\u0000Methods: This prospective observational study was conducted over a six-month period at a public health camp in Sreemangal, Bangladesh. A total of 137 adult participants were purposively selected. Data were collected through a structured questionnaire and physical examination, including measurements of blood pressure and laboratory analysis of blood samples.\u0000Results: The study found that 44.53% of participants had elevated blood pressure, and 21.90% had stage 1 hypertension. Interestingly, 36.50% of participants were unaware of their hypertension status. Furthermore, 26.28% of participants had a known history of diabetes, but blood glucose level analysis revealed an additional 14.85% of participants were prediabetic, and 6.93% were diabetic based on fasting blood glucose levels. A statistically significant association was found between increasing age and the stage of hypertension (p<0.001), and between fasting and normal blood glucose levels and the stage of hypertension (p<0.005 and p<0.05, respectively).\u0000Conclusions: The findings of this study underscore the need for targeted interventions to prevent and manage CVDs in the adult population of Sreemangal, Bangladesh. These interventions should include regular screening for CVD risk factors, health education to increase awareness of these risk factors, and strategies to promote healthy lifestyle behaviors.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"63 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate analysis of histopathological features as prognostic factors in fifty cases of thyroid neoplasm: a retrospective study done at tertiary care centre 组织病理学特征作为五十例甲状腺肿瘤预后因素的多变量分析:一项在三级医疗中心进行的回顾性研究
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240846
Hitesha Bhandari, Anjali Sharma, Rishikesh D. Nilapwar, Praveena G. Vyas, Aditya S. Pawar
Background: Number of prognostic factors for thyroid carcinoma have been identified including age, gender and tumor characteristics, such as histology and stage. The importance of these factors as independent predictors of survival for patients with differentiated thyroid carcinoma has been extensively studied but remains uncertain.Methods: A retrospective analysis of 50 thyroid carcinomas was made to assess prognostic factors including histological variants from September 2019 to February 2022 at our centre. The surgical and histopathological data were studied.Results: 72% patients had papillary thyroid cancer. Multivariate analysis was done and factors showing prognostic significance were tumour size, extrathyroid extension, extranodal extension, lymphovascular, perineural invasion, histological type, necrosis, focality, capsular invasion were found to have poor prognosis.Conclusions: There are histopathological factors which can modify the course and influence the line of treatment of thyroid neoplasms.
背景:已确定的甲状腺癌预后因素包括年龄、性别和肿瘤特征,如组织学和分期。这些因素作为分化型甲状腺癌患者生存率的独立预测因素,其重要性已被广泛研究,但仍不确定:本中心对2019年9月至2022年2月期间的50例甲状腺癌进行了回顾性分析,以评估包括组织学变异在内的预后因素。研究了手术和组织病理学数据:72%的患者为甲状腺乳头状癌。多变量分析显示,肿瘤大小、甲状腺外扩展、结节外扩展、淋巴管、神经周围侵犯、组织学类型、坏死、病灶、囊肿侵犯等因素预后不良:有些组织病理学因素会改变甲状腺肿瘤的病程并影响治疗方案。
{"title":"Multivariate analysis of histopathological features as prognostic factors in fifty cases of thyroid neoplasm: a retrospective study done at tertiary care centre","authors":"Hitesha Bhandari, Anjali Sharma, Rishikesh D. Nilapwar, Praveena G. Vyas, Aditya S. Pawar","doi":"10.18203/2320-6012.ijrms20240846","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240846","url":null,"abstract":"Background: Number of prognostic factors for thyroid carcinoma have been identified including age, gender and tumor characteristics, such as histology and stage. The importance of these factors as independent predictors of survival for patients with differentiated thyroid carcinoma has been extensively studied but remains uncertain.\u0000Methods: A retrospective analysis of 50 thyroid carcinomas was made to assess prognostic factors including histological variants from September 2019 to February 2022 at our centre. The surgical and histopathological data were studied.\u0000Results: 72% patients had papillary thyroid cancer. Multivariate analysis was done and factors showing prognostic significance were tumour size, extrathyroid extension, extranodal extension, lymphovascular, perineural invasion, histological type, necrosis, focality, capsular invasion were found to have poor prognosis.\u0000Conclusions: There are histopathological factors which can modify the course and influence the line of treatment of thyroid neoplasms.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"27 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyand's hernia: an uncommon entity 阿米氏疝气:一种不常见的疾病
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240851
Jorge Silva-Zamora, Arturo Romero Macias, Luis A. Baigts Arriola, Cristian A. Dámazo Escobedo, Adriana G. Vizcarra Rendón, Jose G. Sevilla Flores
A 60-year-old male case whose condition began 6 months prior to admission to the emergency department, presenting an increase in volume in the right inguinal region, with intermittent pain, colic type, with an intensity rating of 8-10/10. On physical examination we found increased volume in the right inguinal region when standing, tumor measuring approximately 5x5 cm, hernia defect approximately 4 cm in diameter, non-painful and reducible. Patient was diagnosed clinically as direct right inguinal hernia and ultrasound confirmed the diagnosis with the presence of the appendix in the sac. A pre-operative diagnosis of right inguinal hernia was made and was planned for hernia mesh repair, during surgery under spinal blockage, the hernia sac was found to contain an appendix without signs of inflammation, so we decided to close the defect and repair with a Lichtenstein mesh hernioplasty without doing an appendectomy. In this case we treated a rare clinical entity called Amyand's hernia. This case highlights the importance of considering Amyand's hernia in the differential diagnosis of inguinal pathologies and the role of imaging modalities in pre-operative diagnosis. Various classification systems have been proposed, including those by Losanoff and Bason, later modified by Rikki et al offering insights into surgical management strategies based on the condition of the appendix and concomitant pathologies. Despite efforts to standardize treatment approaches, consensus on the optimal management strategy remains elusive, necessitating further research to refine diagnostic and therapeutic guidelines.
急诊科收治了一名 60 岁男性患者,他的病情始于入院前 6 个月,表现为右侧腹股沟区体积增大,伴有间歇性疼痛,绞痛类型,疼痛强度为 8-10/10 级。体格检查时,我们发现患者站立时右腹股沟区体积增大,肿瘤大小约为 5x5 厘米,疝气缺损直径约为 4 厘米,无疼痛且可缩小。患者被临床诊断为直接右侧腹股沟疝,超声波确诊囊内存在阑尾。术前诊断为右腹股沟疝,并计划进行疝网修补术,在脊柱阻断下进行手术时,发现疝囊内有阑尾,且无炎症迹象,因此我们决定用 Lichtenstein 网疝成形术缝合缺损并修补,而不进行阑尾切除术。在这个病例中,我们治疗了一种罕见的临床实体--阿米氏疝。本病例强调了在腹股沟病变的鉴别诊断中考虑阿米恩疝的重要性,以及影像学检查在术前诊断中的作用。人们提出了各种分类系统,包括 Losanoff 和 Bason 提出的分类系统,后来 Rikki 等人对其进行了修改,根据阑尾的情况和伴随的病理变化提出了手术治疗策略。尽管人们在努力实现治疗方法的标准化,但对最佳管理策略仍未达成共识,因此有必要开展进一步研究,以完善诊断和治疗指南。
{"title":"Amyand's hernia: an uncommon entity","authors":"Jorge Silva-Zamora, Arturo Romero Macias, Luis A. Baigts Arriola, Cristian A. Dámazo Escobedo, Adriana G. Vizcarra Rendón, Jose G. Sevilla Flores","doi":"10.18203/2320-6012.ijrms20240851","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240851","url":null,"abstract":"A 60-year-old male case whose condition began 6 months prior to admission to the emergency department, presenting an increase in volume in the right inguinal region, with intermittent pain, colic type, with an intensity rating of 8-10/10. On physical examination we found increased volume in the right inguinal region when standing, tumor measuring approximately 5x5 cm, hernia defect approximately 4 cm in diameter, non-painful and reducible. Patient was diagnosed clinically as direct right inguinal hernia and ultrasound confirmed the diagnosis with the presence of the appendix in the sac. A pre-operative diagnosis of right inguinal hernia was made and was planned for hernia mesh repair, during surgery under spinal blockage, the hernia sac was found to contain an appendix without signs of inflammation, so we decided to close the defect and repair with a Lichtenstein mesh hernioplasty without doing an appendectomy. In this case we treated a rare clinical entity called Amyand's hernia. This case highlights the importance of considering Amyand's hernia in the differential diagnosis of inguinal pathologies and the role of imaging modalities in pre-operative diagnosis. Various classification systems have been proposed, including those by Losanoff and Bason, later modified by Rikki et al offering insights into surgical management strategies based on the condition of the appendix and concomitant pathologies. Despite efforts to standardize treatment approaches, consensus on the optimal management strategy remains elusive, necessitating further research to refine diagnostic and therapeutic guidelines.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"75 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated strongyloidiasis in patients on immuno-suppressive therapy 接受免疫抑制治疗的患者中的播散性强直性脊柱炎
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240860
Insaf Kodiyerithodi, Shamsudeen Moideen, Benil Hafeeq, Jyothish Chalil Gopinathan, Bhagyanath T.
Strongyloidiasis is a disease that causes significant morbidity and rarely mortality in immunocompromised patients. We report two cases of disseminated strongyloidiasis infection while on steroids. The first patient was a known diabetic, hypertensive, and coronary artery disease who began on steroids with hemodialysis for biopsy-proven rapidly progressive glomerulo nephritis (RPGN). He presented to the emergency department (ED) with fever, loose stools, worsening dyspnea on exertion, cough, conjunctival congestion, and bilateral lower limb pain of 1-week duration while on hemodialysis (HD). He was started on intravenous (IV) antibiotics, suspecting a catheter-related septicemia. Stool and sputum examination revealed strongyloid infection. The patient was treated with Albendazole, Ivermectin, empirical antibiotics, and tapering and stopping of steroids. Symptoms improved and the patient was discharged in stable condition. The second case is a known case of systemic hypertension and biopsy-proven IgAN on maintenance steroids, with recently detected diabetes mellitus. He presented to the ED with tiredness, fever, cough, dyspnea, and occasional hemoptysis of 1-week duration. On evaluation, he had maculopapular rash over the chest and abdomen, along with hypoxia requiring oxygen support, thrombocytopenia, and worsening renal function. He was initially started on IV antibiotics, suspecting a lower respiratory tract infection with sepsis. Bronchoalveolar lavage (BAL) cytology yielded strogyloid larvae. The patient received ivermectin along with empirical IV antibiotics and supportive treatment but succumbed to the infection. These case reports signify the need for an active search for opportunistic infections in patients who are on continuous immunosuppressive therapy.
在免疫力低下的患者中,强直性脊索蚴病会导致严重的发病率,很少会导致死亡。我们报告了两例在服用类固醇期间感染播散性强丝虫的病例。第一例患者已知患有糖尿病、高血压和冠状动脉疾病,因活检证实的急进性肾小球肾炎(RPGN)开始服用类固醇并进行血液透析。他在接受血液透析(HD)治疗期间,因发热、便稀、用力时呼吸困难加重、咳嗽、结膜充血和双侧下肢疼痛持续一周而到急诊科(ED)就诊。由于怀疑是与导管有关的脓毒血症,医生开始给他静脉注射抗生素。粪便和痰液检查发现了强直性感染。患者接受了阿苯达唑、伊维菌素、经验性抗生素治疗,并逐渐减少和停止使用类固醇。症状有所改善,患者病情稳定后出院。第二个病例是一个已知患有全身性高血压和活检证实患有 IgAN 的病例,正在接受类固醇治疗,最近还查出患有糖尿病。他因疲倦、发热、咳嗽、呼吸困难和偶尔咯血而就诊于急诊室,病程持续一周。经评估,他的胸部和腹部出现斑丘疹,并伴有缺氧,需要吸氧支持,血小板减少,肾功能恶化。由于怀疑是下呼吸道感染并伴有败血症,医生开始给他静脉注射抗生素。支气管肺泡灌洗(BAL)细胞学检查发现了strogyloid幼虫。患者接受了伊维菌素以及经验性静脉注射抗生素和支持治疗,但最终因感染而死亡。这些病例报告表明,在持续接受免疫抑制治疗的患者中,需要积极寻找机会性感染。
{"title":"Disseminated strongyloidiasis in patients on immuno-suppressive therapy","authors":"Insaf Kodiyerithodi, Shamsudeen Moideen, Benil Hafeeq, Jyothish Chalil Gopinathan, Bhagyanath T.","doi":"10.18203/2320-6012.ijrms20240860","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240860","url":null,"abstract":"Strongyloidiasis is a disease that causes significant morbidity and rarely mortality in immunocompromised patients. We report two cases of disseminated strongyloidiasis infection while on steroids. The first patient was a known diabetic, hypertensive, and coronary artery disease who began on steroids with hemodialysis for biopsy-proven rapidly progressive glomerulo nephritis (RPGN). He presented to the emergency department (ED) with fever, loose stools, worsening dyspnea on exertion, cough, conjunctival congestion, and bilateral lower limb pain of 1-week duration while on hemodialysis (HD). He was started on intravenous (IV) antibiotics, suspecting a catheter-related septicemia. Stool and sputum examination revealed strongyloid infection. The patient was treated with Albendazole, Ivermectin, empirical antibiotics, and tapering and stopping of steroids. Symptoms improved and the patient was discharged in stable condition. The second case is a known case of systemic hypertension and biopsy-proven IgAN on maintenance steroids, with recently detected diabetes mellitus. He presented to the ED with tiredness, fever, cough, dyspnea, and occasional hemoptysis of 1-week duration. On evaluation, he had maculopapular rash over the chest and abdomen, along with hypoxia requiring oxygen support, thrombocytopenia, and worsening renal function. He was initially started on IV antibiotics, suspecting a lower respiratory tract infection with sepsis. Bronchoalveolar lavage (BAL) cytology yielded strogyloid larvae. The patient received ivermectin along with empirical IV antibiotics and supportive treatment but succumbed to the infection. These case reports signify the need for an active search for opportunistic infections in patients who are on continuous immunosuppressive therapy.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of perforator propeller flap for the coverage of soft tissue defects over middle and distal part of leg 穿孔器螺旋桨皮瓣覆盖腿部中远端软组织缺损的效果
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240829
M. Nazrul Hossain Mullah, M. Ruhul Amin, M. Noor-E-Alam, Istiaq Sultan, Mosabbir Ahmad Khan, Lailun Nahar, Hasan Nazir Uddin, Tanveer Ahmed
Background: Plastic surgery is a constant battle between blood supply and beauty. The end result of a reconstructive procedure is primarily attributable to the stability of the vascular component, which is fundamental in that it ensures survival and proper functioning of tissues that have been transferred to the recipient site. The aim of the study was to evaluate the clinical outcome of perforator propeller flap for coverage of soft tissue defects in middle and distal legs.Methods: This was a prospective observational study and was conducted in the Department of Plastic Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh during the period from September 2018 to February 2020. The study population includes the total of 30 patients having soft tissue defects of the middle and distal thirds of leg necessary for flap coverage in the Department of Plastic Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh.Results: In total 30 patients maximum 11 (36.7%) were in 31-40 years age group. Majority 27 (90%) were male and 3 (10%) were female in our study. Out of 22 flaps in distal leg necrosis occurred in 4 (18.19%) and among 8 flaps in middle leg necrosis occurred in 1 (12.5%).Conclusions: This study observed that that perforator propeller flaps are ideal in reconstructing soft tissue defects of the middle and distal third of the leg, being safe, easy to perform, providing similar tissue in texture and thickness of damaged tissues, with low donor site morbidity.
背景介绍整形手术是一场供血与美观之间的持久战。整形手术的最终效果主要取决于血管成分的稳定性,因为它是确保转移到受体部位的组织存活和正常功能的基础。本研究旨在评估穿孔器螺旋桨皮瓣覆盖小腿中远端软组织缺损的临床效果:这是一项前瞻性观察研究,于 2018 年 9 月至 2020 年 2 月期间在孟加拉国达卡医学院附属医院整形外科进行。研究对象包括孟加拉国达卡医学院附属医院整形外科的 30 名腿部中、远三分之二软组织缺损需要皮瓣覆盖的患者:在 30 名患者中,31-40 岁年龄段的患者最多,占 11 人(36.7%)。男性占 27 人(90%),女性占 3 人(10%)。在 22 个皮瓣中,有 4 个(18.19%)发生了腿远端皮瓣坏死,在 8 个皮瓣中,有 1 个(12.5%)发生了腿中部皮瓣坏死:本研究发现,穿孔器螺旋桨皮瓣是重建腿中部和远端三分之一处软组织缺损的理想方法,它安全、易于操作,可提供与受损组织质地和厚度相似的组织,且供体部位发病率低。
{"title":"Outcome of perforator propeller flap for the coverage of soft tissue defects over middle and distal part of leg","authors":"M. Nazrul Hossain Mullah, M. Ruhul Amin, M. Noor-E-Alam, Istiaq Sultan, Mosabbir Ahmad Khan, Lailun Nahar, Hasan Nazir Uddin, Tanveer Ahmed","doi":"10.18203/2320-6012.ijrms20240829","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240829","url":null,"abstract":"Background: Plastic surgery is a constant battle between blood supply and beauty. The end result of a reconstructive procedure is primarily attributable to the stability of the vascular component, which is fundamental in that it ensures survival and proper functioning of tissues that have been transferred to the recipient site. The aim of the study was to evaluate the clinical outcome of perforator propeller flap for coverage of soft tissue defects in middle and distal legs.\u0000Methods: This was a prospective observational study and was conducted in the Department of Plastic Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh during the period from September 2018 to February 2020. The study population includes the total of 30 patients having soft tissue defects of the middle and distal thirds of leg necessary for flap coverage in the Department of Plastic Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh.\u0000Results: In total 30 patients maximum 11 (36.7%) were in 31-40 years age group. Majority 27 (90%) were male and 3 (10%) were female in our study. Out of 22 flaps in distal leg necrosis occurred in 4 (18.19%) and among 8 flaps in middle leg necrosis occurred in 1 (12.5%).\u0000Conclusions: This study observed that that perforator propeller flaps are ideal in reconstructing soft tissue defects of the middle and distal third of the leg, being safe, easy to perform, providing similar tissue in texture and thickness of damaged tissues, with low donor site morbidity.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"38 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140366704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A clinico-pathological study of minor salivary gland tumors: experience of our institute 唾液腺小肿瘤的临床病理研究:我院的经验
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240838
Sourabh Sharma, Vikesh Kumar, Konark Thakkar, Yugam Prasad Shandilya
Background: Minor salivary glands are found throughout the entire upper aerodigestive tract. Minor salivary gland neoplasms represent less than 25% of intraoral salivary neoplasms. There are no uniform guidelines at present for treatment for minor salivary gland tumors as these are rare entities. The objective of the study was to evaluate the clinicopathological profile of minor salivary gland tumors and to evaluate follow up of patients after treatment.Methods: The present study was a prospective observational study conducted on 11 patients of the Pacific Medical College and Hospital, Udaipur from 1 December 2020 to 31 December 2023 with complaints of intra-oral swelling with biopsy proven MSGT were included.Results: Out of 11 patients, 7 were female and 4 were male. Highest incidence was found in patients in the 4th-5th decade of life. For most patients, painless swelling was the primary presentation. The most common site for minor salivary cancer was the hard palate 55%. The most common histological types were adenocystic carcinoma. In 10 cases complete surgical excision with clear margins was the preferred mode of treatment. In 1 palliative therapy was required. Among 11 patients, 2 required radiotherapy.Conclusions: MSGT are rare, early diagnosed and resection with wide margins/neck dissections + SOS adjuvant therapy is key to treatment.
背景:小唾液腺遍布整个上消化道。小唾液腺肿瘤占口内唾液腺肿瘤的比例不到 25%。由于小唾液腺肿瘤比较罕见,目前还没有统一的治疗指南。本研究的目的是评估唾液腺小肿瘤的临床病理学特征,并评估患者治疗后的随访情况:本研究是一项前瞻性观察研究,纳入了乌代布尔太平洋医学院和医院 2020 年 12 月 1 日至 2023 年 12 月 31 日期间主诉口腔内肿物并经活检证实为 MSGT 的 11 名患者:结果:11 名患者中有 7 名女性和 4 名男性。第 4-5 个十年期的患者发病率最高。大多数患者主要表现为无痛性肿胀。小涎腺癌最常见的发病部位是硬腭,占 55%。最常见的组织学类型是腺囊肿癌。10例患者首选的治疗方式是边缘清晰的完全手术切除。1例需要姑息治疗。11例患者中有2例需要接受放射治疗:结论:MSGT非常罕见,早期诊断和边缘清晰的切除术/颈部切除术+SOS辅助治疗是治疗的关键。
{"title":"A clinico-pathological study of minor salivary gland tumors: experience of our institute","authors":"Sourabh Sharma, Vikesh Kumar, Konark Thakkar, Yugam Prasad Shandilya","doi":"10.18203/2320-6012.ijrms20240838","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240838","url":null,"abstract":"Background: Minor salivary glands are found throughout the entire upper aerodigestive tract. Minor salivary gland neoplasms represent less than 25% of intraoral salivary neoplasms. There are no uniform guidelines at present for treatment for minor salivary gland tumors as these are rare entities. The objective of the study was to evaluate the clinicopathological profile of minor salivary gland tumors and to evaluate follow up of patients after treatment.\u0000Methods: The present study was a prospective observational study conducted on 11 patients of the Pacific Medical College and Hospital, Udaipur from 1 December 2020 to 31 December 2023 with complaints of intra-oral swelling with biopsy proven MSGT were included.\u0000Results: Out of 11 patients, 7 were female and 4 were male. Highest incidence was found in patients in the 4th-5th decade of life. For most patients, painless swelling was the primary presentation. The most common site for minor salivary cancer was the hard palate 55%. The most common histological types were adenocystic carcinoma. In 10 cases complete surgical excision with clear margins was the preferred mode of treatment. In 1 palliative therapy was required. Among 11 patients, 2 required radiotherapy.\u0000Conclusions: MSGT are rare, early diagnosed and resection with wide margins/neck dissections + SOS adjuvant therapy is key to treatment.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140366785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mycosis fungoides: a rare case report 真菌病:罕见病例报告
Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240858
Ruby Panmei, Angom Ronibala Devi, Mohan Babu B., Y. Devi
Lymphoproliferative disease has many sub-types but the most-commonest subtype of cutaneous T-cell lymphoma is mycosis fungoides (MF). When it presents as solitary or oligo-lesional lesion, radiation therapy is considered potentially curative. This paper presents a case of 17-year-old female who developed two skin lesions in her left knee. She was diagnosed as a case of MF in patch stage. Localised radiation therapy was given to the lesion. MF prognosis depends overall on its stage and is usually better in the early stages. MF is rare and often requires a clinical-pathological correlation for its diagnosis, which is often delayed, especially in the early forms.
淋巴增生性疾病有许多亚型,但最常见的皮肤T细胞淋巴瘤亚型是真菌病(MF)。当它表现为单发或少发性病变时,放射治疗被认为是潜在的治愈方法。本文介绍了一例 17 岁女性的病例,她的左膝出现了两处皮肤病变。她被诊断为斑块期多发性骨髓瘤。患者接受了局部放射治疗。手足口病的预后总体上取决于其分期,通常早期预后较好。手足口病很罕见,通常需要通过临床病理诊断才能确诊,而这往往会延误诊断,尤其是早期手足口病。
{"title":"Mycosis fungoides: a rare case report","authors":"Ruby Panmei, Angom Ronibala Devi, Mohan Babu B., Y. Devi","doi":"10.18203/2320-6012.ijrms20240858","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240858","url":null,"abstract":"Lymphoproliferative disease has many sub-types but the most-commonest subtype of cutaneous T-cell lymphoma is mycosis fungoides (MF). When it presents as solitary or oligo-lesional lesion, radiation therapy is considered potentially curative. This paper presents a case of 17-year-old female who developed two skin lesions in her left knee. She was diagnosed as a case of MF in patch stage. Localised radiation therapy was given to the lesion. MF prognosis depends overall on its stage and is usually better in the early stages. MF is rare and often requires a clinical-pathological correlation for its diagnosis, which is often delayed, especially in the early forms.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"46 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Research in Medical Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1