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Intrathecal baclofen for the management of hereditary spastic paraparesis: a systematic review. 鞘内巴氯芬治疗遗传性痉挛性截瘫:系统综述。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2024-03-01 Epub Date: 2024-01-20 DOI: 10.1097/MRR.0000000000000607
Luisa Viana Pinto, Isabel Romeiro, Filipa Gouveia, Joana Ramalho, Sara Ribeiro Silva, Maria Inês Táboas Simões, Joana Rodrigues Leal

This systematic review aims to evaluate the use of intrathecal baclofen (ITB) for hereditary spastic paraparesis (HSP) treatment. An extensive search in two electronical databases was performed. We identified articles published between 1990 and 2022 (PubMed, Scopus), and applied the following inclusion criteria: diagnosis of HSP at the time of the intervention, either familial or sporadic; report on the effect of ITB in patients with HSP; test trial via either bolus injections or continuous infusion tests; and ITB pump implantation. A data extraction sheet based on the Cochrane Consumers and Communication Review Group's data extraction template was created and adapted to collect relevant data. A qualitative analysis was performed to present the results in narrative summary fashion. A total of 6 studies met our inclusion criteria. 51 patients with HSP had a pre-implantation ITB trial. The time since the diagnosis until the pump implantation ranged from 5 to 30 years. The initial bolus ranged from 20 to 50 μg and the mean doses used at steady state ranged from 65 to 705 μg. An improvement in spasticity was observed on the modified Ashworth Scale in patients treated with ITB. Although all studies reported a subjective gait improvement, not all found an objective improvement in gait. The most common side effect reported was catheter-related problems. The findings of this review support the use of ITB as an effective and a viable option for the treatment of spasticity in HSP refractory to conservative therapies.

本系统综述旨在评估鞘内巴氯芬(ITB)在遗传性痉挛性截瘫(HSP)治疗中的应用。我们在两个电子数据库中进行了广泛的检索。我们确定了 1990 年至 2022 年间发表的文章(PubMed、Scopus),并采用了以下纳入标准:干预时诊断为 HSP(家族性或散发性);关于 ITB 对 HSP 患者疗效的报告;通过栓剂注射或连续输注测试进行的试验;以及 ITB 泵植入。我们根据 Cochrane 消费者与沟通审查小组的数据提取模板制作并调整了数据提取表,以收集相关数据。我们进行了定性分析,以叙述总结的方式呈现结果。共有 6 项研究符合我们的纳入标准。51 名 HSP 患者接受了植入前 ITB 试验。从确诊到植入泵的时间从 5 年到 30 年不等。初始栓塞剂量从 20 微克到 50 微克不等,稳态时的平均剂量从 65 微克到 705 微克不等。根据改良的阿什沃斯量表,接受 ITB 治疗的患者痉挛状况有所改善。虽然所有研究都报告了主观步态的改善,但并非所有研究都发现了客观步态的改善。最常见的副作用是导管相关问题。本综述的研究结果支持使用 ITB 作为治疗保守疗法难治的 HSP 痉挛的一种有效且可行的方法。
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引用次数: 0
Barriers and facilitators to physical activity participation among community-dwelling physically inactive individuals after stroke: a qualitative exploratory study. 中风后在社区居住的非体育活动人士参与体育活动的障碍和促进因素:一项定性探索性研究。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2024-03-01 Epub Date: 2024-01-06 DOI: 10.1097/MRR.0000000000000610
Evrim Karadag-Saygi, Esra Giray, Nurullah Eren, Gunay Yolcu, Ozge Kenis Coskun, Serap Cifcili

Physical activity has been shown to reduce the risk for first-ever stroke as well as recurrent stroke with positive effects on almost all known modifiable risk factors. However, the perceived barriers and facilitators for engaging in physical activity have been insufficiently studied and may differ between cultures. Therefore, the aim of this study was to explore the perceptions of community-dwelling physically inactive individuals with stroke about barriers and facilitators to their participation in physical activity. This qualitative study included two focus groups of ten individuals with stroke classified as physically inactive based on accelerometer recordings. A semi-structured set of questions was posed in each focus group session and the transcripts were analysed using thematic analysis. The results revealed three main themes and subthemes: individual factors (physical impairments, psychological factors, spirituality), interaction with the family (attitudes of family members/close community) and social and environmental factors (hobbies, lack of or presence of facilities, the use of orthosis). We conclude that physical activity participation is affected by a multitude of factors as well as cultural differences. Thus, interventions aimed at increasing participation in physical activity after stroke should not only be planned according to individual clinical characteristics but also take into account a range of personal-to-social factors, including cultural differences.

事实证明,体育锻炼可降低首次中风和复发中风的风险,对几乎所有已知的可改变风险因素都有积极影响。然而,对参与体育锻炼的障碍和促进因素的认识研究不足,而且不同文化之间可能存在差异。因此,本研究旨在探讨居住在社区的非体力活动中风患者对参与体育锻炼的障碍和促进因素的看法。这项定性研究包括两个焦点小组,由 10 名根据加速度计记录被归类为身体不活跃的中风患者组成。每个焦点小组会议都提出了一系列半结构化问题,并使用主题分析法对记录誊本进行了分析。结果发现了三个主要主题和次主题:个人因素(身体缺陷、心理因素、精神因素)、与家庭的互动(家庭成员/近邻社区的态度)以及社会和环境因素(爱好、设施缺乏或存在、矫形器的使用)。我们的结论是,体育活动的参与受到多种因素和文化差异的影响。因此,旨在提高脑卒中后体育活动参与率的干预措施不仅要根据个体临床特征进行规划,还要考虑一系列个人与社会因素,包括文化差异。
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引用次数: 0
Reliability of the Montreal Cognitive Assessment in people with stroke. 蒙特利尔认知评估在中风患者中的可靠性。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2024-03-01 Epub Date: 2024-01-06 DOI: 10.1097/MRR.0000000000000612
Hiu-Ying Lau, Yi-Hung Lin, Keh-Chung Lin, Yi-Chun Li, Grace Yao, Chih-Yu Lin, Yi-Hsuan Wu

This study examined the relative and absolute reliability of the Taiwanese version of the MoCA (MoCA-T) in people with stroke. The study recruited 114 individuals who were at least 3 months after the onset of a first-ever unilateral stroke. The MoCA-T was administered twice, at a 6-week interval, to all participants. The relative reliability was assessed using the intraclass correlation coefficient (ICC), and the absolute reliability was assessed using standard error of measurement (SEM), the smallest real difference (SRD), the SRD percentage, and the Bland-Altman method. The ICC analysis showed the MoCA-T was highly reliable (ICC = 0.85). The absolute reliability was between an acceptable and excellent level, where the SEM and the SRD at the 95% confidence interval were 1.38 and 3.83, respectively. The Bland-Altman analyses showed no systematic bias between repeated measurements. The range of the 95% limits of agreement was narrow, indicating a high level of stability over time. These findings suggest that the MoCA-T has high agreement between repeated measurements without systematic bias. The threshold to detect real change stands between an acceptable and excellent level. The MoCA-T is a reliable tool for cognitive screening in stroke rehabilitation.

本研究考察了台湾版 MoCA(MoCA-T)在脑卒中患者中的相对和绝对可靠性。研究招募了 114 名首次单侧脑卒中发病至少 3 个月后的患者。对所有参与者进行了两次 MoCA-T,每次间隔 6 周。相对可靠性采用类内相关系数(ICC)进行评估,绝对可靠性采用测量标准误差(SEM)、最小实际差异(SRD)、SRD 百分比和布兰德-阿尔特曼法进行评估。ICC 分析表明,MoCA-T 具有高度可靠性(ICC = 0.85)。绝对可靠度介于可接受和优秀之间,在 95% 置信区间内的 SEM 和 SRD 分别为 1.38 和 3.83。布兰-阿尔特曼分析表明,重复测量之间没有系统性偏差。95%的一致性界限范围较窄,表明随着时间的推移稳定性较高。这些结果表明,MoCA-T 在重复测量之间具有很高的一致性,没有系统性偏差。检测实际变化的阈值介于可接受水平和优秀水平之间。MoCA-T 是脑卒中康复认知筛查的可靠工具。
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引用次数: 0
Editorial: message from the new Editor-in-Chief. 社论:新主编的致辞。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2024-03-01 Epub Date: 2024-01-06 DOI: 10.1097/MRR.0000000000000615
Dobrivoje S Stokic
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引用次数: 0
Reproducibility and content validity of the Slovenian version of the STarT Back Screening Tool for chronicity risk assessment in patients with low back pain. 斯洛文尼亚版STarT背部筛查工具用于腰痛患者慢性风险评估的可重复性和内容有效性。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-10-16 DOI: 10.1097/MRR.0000000000000604
Marinka Cimerman, Alan Kacin

Chronic pain is the most common cause of impaired work ability and thus represents a significant social and economic burden. STarT Back Screening Tool (SBT) is the most often used screening tool for rapid identification and classification of patients for their risk of development of chronic low back pain, which is valid and reliable in the original English version and translation into other languages. The aim of the present study was to translate the SBT into Slovenian and to evaluate its content validity and reliability. We translated the SBT from English into Slovenian and back according to the standard protocol. We tested its metric properties on a group of patients with low back pain aged 18 to 65 years. The reliability of the reassessment was calculated using the ICC and specific agreement, while the content validity of the questionnaire was determined using the ceiling and floor effect. Of the 42 patients who participated in the study, 42.9% were at low risk, 33.3% were at moderate risk, and 23.8% were at high risk of developing chronic pain, according to the SBT. The ICC for the entire sample was 0.96 (95% CI 0.92-0.98). The Slovenian translation of the SBT showed excellent specific agreement between the initial and repeat assessments: 91.4% for the low-risk group, 85.7% for the moderate-risk group, and 95.2% for the high-risk group. In addition, it showed good content validity, as no ceiling or floor effects were detected. The Slovenian translation of the questionnaire is suitable for clinical use.

慢性疼痛是工作能力受损的最常见原因,因此是一种重大的社会和经济负担。STarT背部筛查工具(SBT)是最常用的筛查工具,用于快速识别和分类患者患慢性腰痛的风险,其英文原版和翻译成其他语言都是有效和可靠的。本研究的目的是将SBT翻译成斯洛文尼亚语,并评估其内容的有效性和可靠性。我们根据标准协议将SBT从英语翻译成斯洛文尼亚语并返回。我们在一组18至65岁的腰痛患者身上测试了它的度量特性。使用ICC和具体协议计算重新评估的可靠性,而使用上限和下限效应确定问卷的内容有效性。根据SBT,在参与研究的42名患者中,42.9%的患者处于低风险,33.3%的患者处于中风险,23.8%的患者处于慢性疼痛的高风险。整个样本的ICC为0.96(95%CI 0.92-0.98)。SBT的斯洛文尼亚语翻译在初始和重复评估之间显示出极好的特异性一致性:低风险组为91.4%,中风险组为85.7%,高风险组为95.2%。此外,由于没有检测到天花板或地板效应,它显示出良好的内容有效性。调查表的斯洛文尼亚语译文适合临床使用。
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引用次数: 0
Cognitive status and sleep quality can explain the fear of falling and fall history in people with Parkinson's disease. 认知状态和睡眠质量可以解释帕金森病患者对跌倒的恐惧和跌倒史。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-08-15 DOI: 10.1097/MRR.0000000000000596
Nesreen Alissa, Reem Rehan, Alham Al-Sharman, Mariem Latrous, Ala' S Aburub, Khalid El-Salem, Linzette Morris, Hanan Khalil

Fear of falling (FOF) is highly prevalent in people with Parkinson's disease (PwPD) and contributes to high fall risk. Studies reporting on the relationship between falls, FOF, and non-motor factors such as cognitive function and sleep quality in Parkinson's disease are limited. This study aimed to investigate (1) the relationship of cognitive function and sleep quality with FOF, and history of falls in PwPD; (2) differences in cognitive function and sleep quality between Parkinson's disease fallers and non-fallers; and (3) a cut-off score for cognitive function and sleep quality to discriminate Parkinson's disease fallers from non-fallers. Fifty PwPD were assessed for FOF [Falls Efficacy Scale-International (FES-I)], cognition [Montréal Cognitive Assessment (MOCA)], sleep quality [Pittsburgh Sleep Quality Index (PSQI)], and falls history. The MOCA is significantly associated with FES-I scores ( R2  = 0.429, P  < 0.0001). Both MOCA ( P  = 0.012) and PSQI ( P  = 0.027) were associated with falls history even after adjusting for confounding factors (age, sex, L-dopa use, Parkinson's disease severity). Both MOCA and PSQI scores were able to distinguish fallers from non-fallers with cut-off scores of 15.5 and 7.5, respectively. Although our findings revealed that both cognitive function and sleep quality are important factors influencing falls and FOF in PwPD, it remains to be determined if addressing cognitive impairments and poor sleep quality may favorably impact balance before integrating such screenings into fall prevention programs.

对跌倒的恐惧(FOF)在帕金森病(PwPD)患者中非常普遍,并导致高跌倒风险。关于帕金森病患者跌倒、FOF和认知功能和睡眠质量等非运动因素之间关系的研究报道有限。本研究旨在探讨(1)认知功能和睡眠质量与PwPD患者FOF和跌倒史的关系;(2) 帕金森病跌倒者和非跌倒者认知功能和睡眠质量的差异;以及(3)认知功能和睡眠质量的临界分数,以区分帕金森病患者和非患者。对50名PwPD进行了FOF[国际跌倒疗效量表(FES-I)]、认知[蒙特利尔认知评估(MOCA)]、睡眠质量[匹兹堡睡眠质量指数(PSQI)]和跌倒史评估。MOCA与FES-I评分显著相关(R2 = 0.429,P
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引用次数: 0
Clinimetric evaluation of five clinically feasible measures of the leg extensor muscle strength in neurological rehabilitation settings. 神经康复环境中五种临床可行的腿部伸肌力量测量方法的临床评估。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-07-11 DOI: 10.1097/MRR.0000000000000594
Edwina J Sutherland, Michelle B Kahn, Gavin P Williams

A gold-standard clinical measure of leg muscle strength has not been established. Therefore, the aim of this study was to evaluate clinimetric properties of five clinically feasible measures of lower-limb extensor muscle strength in neurological rehabilitation settings. This was a cross-sectional observational study of 36 participants with leg weakness as a result of a neurological condition/injury. Participants were recruited across a range of walking abilities, from non- to independently ambulant. Each was assessed using each of the following five measures: manual muscle test (MMT), hand-held dynamometry (HHD), seated single leg press one repetition maximum (1RM), functional sit-to-stand (STS) test and seated single leg press measured with a load cell. Each clinical measure was evaluated for its discriminative ability, floor/ceiling effects, test-retest reliability and clinical utility. The load cell and HHD were the most discriminative of the tests and were also resistant to floor/ceiling effects; however, the load cell was superior to the HHD when compared for its clinical utility. The MMT/STS tests received perfect scores for clinical utility, although similar to the 1RM test, they were susceptible to floor and ceiling effects. The load cell leg press test was the only measure of lower limb strength to satisfy all four clinimetric properties. Implications for clinical practice include, firstly, that strength tests available to clinicians vary in their clinimetric properties. Secondly, the functional status of the person will determine selection of the best clinical strength test. And lastly, load cell device technology should be considered for clinical strength assessments.

腿部肌肉力量的金标准临床测量尚未建立。因此,本研究的目的是评估神经康复环境中五种临床可行的下肢伸肌力量测量方法的临床特性。这是一项针对36名因神经系统疾病/损伤而出现腿部无力的参与者的横断面观察性研究。参与者被招募到一系列的行走能力,从非行走能力到独立行走能力。使用以下五种测量方法中的每一种进行评估:手动肌肉测试(MMT)、手持式测力仪(HHD)、最大重复一次的坐姿单腿按压(1RM)、功能性坐立式(STS)测试和用称重传感器测量的坐姿单脚按压。评估每项临床测量的辨别能力、下限/上限效应、重测可靠性和临床实用性。称重传感器和HHD是最具鉴别力的测试,也能抵抗地板/天花板的影响;然而,就其临床实用性而言,称重传感器优于HHD。MMT/STS测试在临床实用性方面获得了完美的分数,尽管与1RM测试类似,它们容易受到地板和天花板效应的影响。测压元件腿部压力测试是唯一能满足所有四种临床特性的下肢强度测量方法。对临床实践的影响包括,首先,临床医生可以使用的强度测试在其临床特性上各不相同。其次,患者的功能状态将决定最佳临床力量测试的选择。最后,称重传感器设备技术应被考虑用于临床强度评估。
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引用次数: 0
Discharge outcomes as predictors of social participation in the community after a stroke: a cohort study. 出院结果作为卒中后社区社会参与的预测因素:一项队列研究。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-08-03 DOI: 10.1097/MRR.0000000000000599
Flaviane Ribeiro de Souza, Matheus Sales, Larrie Rabelo Laporte, Ailton Melo, Nildo Manoel da Silva Ribeiro

The mapping of possible predictors of restrictions in the social participation of people after stroke in the community can be an essential tool to support the development of rehabilitation strategies even in the hospital environment. This study aimed to identify whether mobility, functional balance and dependence on functionality at hospital discharge can predict restrictions on social participation 1 year after stroke in the community. This is a hospital-based cohort study, with individuals over 18 years old admitted with a diagnosis of acute stroke included. People with dementia, previous functional limitations and cancer patients were omitted. Mobility, balance and functional independence were the predictor variables at hospital discharge, and the outcome of interest was social participation assessed 1 year after a stroke in the community. Forty-eight patients were included after a 1-year follow-up. The degree of functional independence at hospital discharge ( β  = 0.813; P  < 0.01) was the independent predictor of social participation, specifically the locomotion ( β  = 0.452; P  < 0.001) and social cognition ( β  = 0.462; P  < 0.001) related to functional independence. Mobility ( β  = 0.040; P  = 0.777) and functional balance ( β  = 0.060; P  = 0.652) did not show an independent association. Cognitive functional independence was a predictor of daily activities ( β  = 0.786; P  < 0.001), social roles ( β  = 0.390; P  = 0.014) and satisfaction ( β  = 0.564; P  < 0.001) of social participation. The degree of functional independence of people after a stroke at hospital discharge was able to predict the level of social involvement in the community one year after the stroke.

绘制中风患者在社区中社会参与限制的可能预测因素,即使在医院环境中,也可以成为支持康复策略制定的重要工具。这项研究旨在确定出院时的行动能力、功能平衡和对功能的依赖是否可以预测社会参与的限制1 社区中风后一年。这是一项基于医院的队列研究,研究对象为18岁以上的人 岁,诊断为急性中风。痴呆症患者、既往功能受限患者和癌症患者被忽略。流动性、平衡性和功能独立性是出院时的预测变量,感兴趣的结果是社会参与评估1 社区中风一年后。48名患者在一年的随访后被纳入。出院时的功能独立程度(β = 0.813;P
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引用次数: 0
Reliability and validity of the T-shirt test for the assessment of unsupported sitting in manual wheelchair users with spinal cord injury. T恤测试用于评估无支撑坐在手动轮椅使用者脊髓损伤的可靠性和有效性。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-08-15 DOI: 10.1097/MRR.0000000000000600
Francielle Romanini, Rafaella M Zambetta, Natália Padula, Roberta C Gaspar, Thiago L Russo, Jocemar Ilha

This study aimed to evaluate the validity and reliability of the T-shirt test (TST) in assessing sitting stability under three thigh support conditions and with timed outcomes derived in six ways among individuals with a spinal cord injury (SCI). The TST was performed five times under three thigh support conditions (85%, 55% and 25% of total thigh length) in two evaluations spaced between 7-14 days. For each thigh condition, six different outcomes were derived (average or best time from 2, 3, and 5 trial). All outcomes derivation showed excellent reliability on test day (intraclass correlation coefficient; ICC  ≥ 0.997) and excellent test-retest reliability (ICC ≥ 0.874) for each thigh support condition. The TST showed high inverse correlations with the Spinal Cord Independence Measure III (SCIM)-mobility score for all outcomes and support conditions (ρ≥-0.706), except for Best-5; moderate inverse correlations with total SCIM-total scores for most outcome derivations and support conditions (ρ≥-0.636); and a moderate inverse correlation with confidence and capacity domains of Wheelchair Skills Test-Questionnaire for most outcome derivation and support conditions (ρ≥-0.504). The TST could discriminate cervical from high and low thoracic levels of injuries under minimal thigh support condition. Overall, all the TST-derived outcomes and support conditions showed adequate validity and test-retest reliability, but Best-5 had inconsistency. Under the minimal thigh support condition, all outcome derivations except Best-3 could discriminate cervical from other injury-level groups. Although all outcome derivations and thigh support conditions provided reliable results, we recommend using the average of 3 trials under the maximal thigh support condition.

本研究旨在评估T恤测试(TST)在评估三种大腿支撑条件下的坐姿稳定性方面的有效性和可靠性,并通过六种方式得出脊髓损伤(SCI)患者的时间结果。在间隔7-14天的两次评估中,在三种大腿支撑条件下(占大腿总长度的85%、55%和25%)进行了五次TST。对于每种大腿状况,得出六种不同的结果(2、3和5次试验的平均或最佳时间)。所有结果推导在测试日显示出良好的可靠性(组内相关系数;ICC ≥ 0.997)和良好的重测可靠性(ICC ≥ 0.874)。除Best-5外,TST与所有结果和支持条件下的脊髓独立性测量III(SCIM)-活动性评分呈高度负相关(ρ≥-0.706);在大多数结果推导和支持条件下,与SCIM总分呈中度负相关(ρ≥-0.636);在大多数结果推导和支持条件下,与轮椅技能测试问卷的置信度和能力域呈中度负相关(ρ≥-0.504)。TST可以在最小大腿支持条件下区分颈部和胸部的损伤程度。总体而言,所有TST得出的结果和支持条件都显示出足够的有效性和重新测试的可靠性,但Best-5存在不一致性。在最小大腿支撑条件下,除Best-3外的所有结果推导都可以区分宫颈损伤和其他损伤水平组。尽管所有结果推导和大腿支撑条件都提供了可靠的结果,但我们建议在最大大腿支撑条件下使用3次试验的平均值。
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引用次数: 0
The effectiveness of home-based therapeutic exercises on adults with fibromyalgia: a systematic review and meta-analysis. 家庭治疗性锻炼对成人纤维肌痛的有效性:一项系统综述和荟萃分析。
IF 1.5 4区 医学 Q3 REHABILITATION Pub Date : 2023-12-01 Epub Date: 2023-10-31 DOI: 10.1097/MRR.0000000000000606
Esra' Saleh, Mohammad A Yabroudi, Mohammad Al-Wardat, Zakariya H Nawasreh, Khader Almhdawi, Mohammad Etoom

The objective of this systematic review and meta-analysis is to evaluate the effectiveness of home-based exercises (HBE) in alleviating pain, fatigue, depression, and anxiety and enhancing the quality of life (QOL) among adults with fibromyalgia. A comprehensive search was conducted across four databases PubMed, Cochrane, CINAHL (EBSCO), and PEDro to identify eligible randomized controlled trials (RCTs). Standardized mean differences (SMDs) at a 95% confidence interval (CI) were computed. Ten RCTs met the inclusion criteria, involving 601 participants, with a good-to-fair quality according to the PEDro scale. Of the 10 included studies, 3 compared HBE to no exercise, while 7 compared HBE to center-based exercises (CBE). HBE showed significant pain reduction (SMD = 0.775, P = 0.003) and improved QOL as measured by the fibromyalgia impact questionnaire (FIQ) (SMD = 0.621, P = 0.001) compared with no exercise, but there were no significant differences in depression and QOL as measured by SF-36 compared with CBE. In contrast, CBE demonstrated greater pain reduction (SMD = -1.325, P < 0.001) and improved FIQ scores (SMD = -0.843, P = 0.017) compared with HBE. In conclusion, HBE exhibit effectiveness in alleviating pain, and depression and enhancing QOL among fibromyalgia patients in comparison to no exercise. However, CBE are more effective in reducing pain and enhancing QOL than HBE, although HBE can be valuable for maintaining activity levels in fibromyalgia patients between treatment cycles.

本系统综述和荟萃分析的目的是评估家庭锻炼(HBE)在减轻成人纤维肌痛患者的疼痛、疲劳、抑郁和焦虑以及提高生活质量(QOL)方面的有效性。在PubMed、Cochrane、CINAHL(EBSCO)和PEDro四个数据库中进行了全面搜索,以确定符合条件的随机对照试验(RCT)。计算95%置信区间(CI)下的标准化平均差(SMD)。10项随机对照试验符合入选标准,涉及601名参与者,根据PEDro量表,质量良好至尚可。在纳入的10项研究中,3项将HBE与不锻炼进行了比较,7项将HBE与中心锻炼(CBE)进行了比较。与不运动相比,HBE显示出显著的疼痛减轻(SMD=0.775,P=0.003)和纤维肌痛影响问卷(FIQ)测量的生活质量改善(SMD=0.621,P=0.001),但与CBE相比,SF-36测量的抑郁和生活质量没有显著差异。相反,与HBE相比,CBE表现出更大的疼痛减轻(SMD=-1.325,P<0.001)和FIQ评分改善(SMD=-0.843,P=0.017)。总之,与不运动相比,HBE在减轻纤维肌痛患者的疼痛、抑郁和提高生活质量方面表现出有效性。然而,CBE在减轻疼痛和提高生活质量方面比HBE更有效,尽管HBE对于在治疗周期之间维持纤维肌痛患者的活动水平是有价值的。
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International Journal of Rehabilitation Research
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