{"title":"Editorial Comment to ‘Validation of the Pubo-Urethral Stump Angle as a Predictive Parameter for Elaborate Anastomotic Urethroplasty in Pelvic Fracture Urethral Injury’","authors":"Akihiro Kanematsu","doi":"10.1111/iju.70340","DOIUrl":"https://doi.org/10.1111/iju.70340","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145964166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Since Japan's public insurance covered robot-assisted radical prostatectomy (RARP) in 2012, it has become standard. Despite widespread use, variability exists among surgeons in approaches, nerve-sparing, lymph node dissection (LND), and postoperative management. This study examined the practices of surgical technique selection, energy settings, and postoperative management in RARP across Japan to identify standardization opportunities.
Materials and Methods
A 50-item questionnaire was distributed between October and December 2023 to physicians performing robotic surgeries at 44 institutions affiliated with Kyoto University and other universities. The survey addressed the surgeons' experience, robotic platforms, energy settings, surgical approaches, LND, anastomosis, complication prevention, and postoperative management. Responses from 147 physicians were analyzed.
Results
All respondents used the da Vinci system, with the half of institutions performing over 50 RARP annually. Most surgeons preferred the transperitoneal approach (over 80%) and standard LND (65.7%), while 20% performed an extended pelvic lymph node dissection. Monopolar and bipolar energies were set to Effects 3 and 4, respectively. Barbed sutures were used for anastomosis in 90% of the cases with posterior wall reconstruction. Drains were placed in 70% of the cases, and catheters were removed on postoperative days 5–7 in over 90%. Variations were noted in dorsal venous complex management, nerve-sparing, hernia prevention, and imaging before catheter removal.
Conclusions
This survey revealed the diversity of RARP techniques and postoperative protocols among Japanese surgeons. While fundamental elements, such as LND templates and barbed anastomosis, have converged, significant procedural variability persists. A two-tiered educational model, which standardizes essential safety techniques while allowing case-specific flexibility, may promote consistent nationwide RARP practices.
{"title":"Technique Selection for Robot-Assisted Radical Prostatectomy: A Multi-Institutional Survey in Japan","authors":"Norihiko Masuda, Tatsuya Hazama, Toshihide Hosomi, Kazuto Imai, Toshiya Akao","doi":"10.1111/iju.70347","DOIUrl":"10.1111/iju.70347","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Since Japan's public insurance covered robot-assisted radical prostatectomy (RARP) in 2012, it has become standard. Despite widespread use, variability exists among surgeons in approaches, nerve-sparing, lymph node dissection (LND), and postoperative management. This study examined the practices of surgical technique selection, energy settings, and postoperative management in RARP across Japan to identify standardization opportunities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A 50-item questionnaire was distributed between October and December 2023 to physicians performing robotic surgeries at 44 institutions affiliated with Kyoto University and other universities. The survey addressed the surgeons' experience, robotic platforms, energy settings, surgical approaches, LND, anastomosis, complication prevention, and postoperative management. Responses from 147 physicians were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All respondents used the da Vinci system, with the half of institutions performing over 50 RARP annually. Most surgeons preferred the transperitoneal approach (over 80%) and standard LND (65.7%), while 20% performed an extended pelvic lymph node dissection. Monopolar and bipolar energies were set to Effects 3 and 4, respectively. Barbed sutures were used for anastomosis in 90% of the cases with posterior wall reconstruction. Drains were placed in 70% of the cases, and catheters were removed on postoperative days 5–7 in over 90%. Variations were noted in dorsal venous complex management, nerve-sparing, hernia prevention, and imaging before catheter removal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This survey revealed the diversity of RARP techniques and postoperative protocols among Japanese surgeons. While fundamental elements, such as LND templates and barbed anastomosis, have converged, significant procedural variability persists. A two-tiered educational model, which standardizes essential safety techniques while allowing case-specific flexibility, may promote consistent nationwide RARP practices.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145966012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomohiro Iwasawa, Takuya Tsujino, Shigehiro Tsukahara, Hiroshi Fukushima, Daisuke Ito, Eisuke Tomiyama, Fumihiko Urabe, the Japanese Young Urologist Basic Research Collaboration
Urothelial carcinoma (UC), encompassing both bladder cancer and upper tract UC, is a biologically heterogeneous malignancy that has long complicated patient stratification and therapeutic prediction. Recent genomic and transcriptomic analyses, however, have delineated reproducible molecular subtypes across non-muscle-invasive and muscle-invasive disease. These classification frameworks have refined biological understanding and improved both risk stratification and treatment selection. Emerging evidence also indicates that genomic alterations, such as FGFR3 mutations, may confer distinct immunologic phenotypes within specific transcriptomic contexts, thereby challenging prior assumptions. The advent of immune checkpoint inhibitors has transformed UC management, yet variable response rates underscore the complexity of the tumor microenvironment (TME). Single-cell and spatial analyses have identified immune-inflamed, -desert, and -excluded TME subtypes, with cancer-associated fibroblasts playing a key role in immune exclusion and therapeutic resistance. Liquid biopsy, particularly circulating tumor DNA, has demonstrated utility for real-time disease monitoring, minimal residual disease detection, and treatment stratification, as highlighted in trials such as IMvigor010 and IMvigor011. Urinary extracellular vesicles also represent promising non-invasive biomarkers, though further standardization is required. In addition, novel therapeutic strategies—including antibody-drug conjugates, gene therapies, and sustained-release delivery systems—are broadening treatment options across disease stages. Collectively, these translational advances mark a paradigm shift toward precision immuno-oncology in UC. Nonetheless, successful clinical implementation will require prospective validation, optimized analytical platforms, and sustained physician-scientist engagement to translate these discoveries into improved patient outcomes. This review provides a comprehensive overview of recent progress in UC translational research, with a focus on genomic and transcriptomic insights, the evolving role of immunotherapy, advances in liquid biopsy, and the development of novel therapeutics.
{"title":"Translational Advances in Urothelial Carcinoma: From Bench to Bedside","authors":"Tomohiro Iwasawa, Takuya Tsujino, Shigehiro Tsukahara, Hiroshi Fukushima, Daisuke Ito, Eisuke Tomiyama, Fumihiko Urabe, the Japanese Young Urologist Basic Research Collaboration","doi":"10.1111/iju.70341","DOIUrl":"10.1111/iju.70341","url":null,"abstract":"<p>Urothelial carcinoma (UC), encompassing both bladder cancer and upper tract UC, is a biologically heterogeneous malignancy that has long complicated patient stratification and therapeutic prediction. Recent genomic and transcriptomic analyses, however, have delineated reproducible molecular subtypes across non-muscle-invasive and muscle-invasive disease. These classification frameworks have refined biological understanding and improved both risk stratification and treatment selection. Emerging evidence also indicates that genomic alterations, such as <i>FGFR3</i> mutations, may confer distinct immunologic phenotypes within specific transcriptomic contexts, thereby challenging prior assumptions. The advent of immune checkpoint inhibitors has transformed UC management, yet variable response rates underscore the complexity of the tumor microenvironment (TME). Single-cell and spatial analyses have identified immune-inflamed, -desert, and -excluded TME subtypes, with cancer-associated fibroblasts playing a key role in immune exclusion and therapeutic resistance. Liquid biopsy, particularly circulating tumor DNA, has demonstrated utility for real-time disease monitoring, minimal residual disease detection, and treatment stratification, as highlighted in trials such as IMvigor010 and IMvigor011. Urinary extracellular vesicles also represent promising non-invasive biomarkers, though further standardization is required. In addition, novel therapeutic strategies—including antibody-drug conjugates, gene therapies, and sustained-release delivery systems—are broadening treatment options across disease stages. Collectively, these translational advances mark a paradigm shift toward precision immuno-oncology in UC. Nonetheless, successful clinical implementation will require prospective validation, optimized analytical platforms, and sustained physician-scientist engagement to translate these discoveries into improved patient outcomes. This review provides a comprehensive overview of recent progress in UC translational research, with a focus on genomic and transcriptomic insights, the evolving role of immunotherapy, advances in liquid biopsy, and the development of novel therapeutics.</p>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iju.70341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment on “The Evolution of Prostate Multiparametric MRI and Its Application in Prostate Cancer Clinical Management”","authors":"Yoshiko Ueno","doi":"10.1111/iju.70353","DOIUrl":"10.1111/iju.70353","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to examine trends in frequency of sexual intercourse and sexual function among Japanese men over the past 30 years by comparing the Nationwide Survey conducted by the Japanese Society for Sexual Medicine in 2023 with the Sapporo Survey conducted by the Department of Urology, Sapporo Medical University, in 1991.
Methods
Three domains were analyzed: sexual intercourse, penile rigidity, and morning erections in both studies. To minimize inconsistencies, definitions were standardized. The 2023 survey included 3795 men aged 20–79 years, while the 1991 survey comprised 8893 participants for sexual intercourse, 7517 for morning erections, and 3886 for penile rigidity. Case numbers differed by item in 1991 owing to incomplete responses. The 1991 survey targeted only married individuals; comparable analyses were performed using married participants extracted from the 2023 dataset.
Results
1. Sexual intercourse: Compared with the 1991 Sapporo Survey, the proportion of men reporting sexual intercourse less than once per month was significantly higher across all age groups in the 2023 Nationwide Survey, except among men in their 20s. 2. Penile rigidity: The proportion of men with insufficient penile rigidity for penetration was significantly higher in 2023 than in 1991 across all age groups except those aged ≥ 75 years. 3. Morning erections: Men reporting complete absence of morning erections were significantly more common in 2023 across all age groups.
Conclusion
Over the past three decades, Japanese men have shown substantial declines in the frequency of sexual intercourse, penile rigidity, and the frequency of morning erections, particularly in younger and middle-aged cohorts.
{"title":"Three Decades of Change in Frequency of Sexual Intercourse and Sexual Function Among Japanese Men: A Comparative National Survey","authors":"Yoshikazu Sato, Akira Tsujimura, Masato Shirai, Haruaki Sasaki, Ko Kobayashi, Hiroki Horita, Aoki Masaharu, Nobukazu Suzuki, Shinichi Hisasue, Shinichiro Fukuhara, Koji Chiba, Tsuyoshi Yoshizawa, Hikaru Tomoe, Kazunori Kimura, Eiji Kikuchi, Eri Maeda, Atsushi Nagai, Koichi Nagao, Taiji Tsukamoto, Naoya Masumori","doi":"10.1111/iju.70344","DOIUrl":"10.1111/iju.70344","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to examine trends in frequency of sexual intercourse and sexual function among Japanese men over the past 30 years by comparing the Nationwide Survey conducted by the Japanese Society for Sexual Medicine in 2023 with the Sapporo Survey conducted by the Department of Urology, Sapporo Medical University, in 1991.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Three domains were analyzed: sexual intercourse, penile rigidity, and morning erections in both studies. To minimize inconsistencies, definitions were standardized. The 2023 survey included 3795 men aged 20–79 years, while the 1991 survey comprised 8893 participants for sexual intercourse, 7517 for morning erections, and 3886 for penile rigidity. Case numbers differed by item in 1991 owing to incomplete responses. The 1991 survey targeted only married individuals; comparable analyses were performed using married participants extracted from the 2023 dataset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>1. Sexual intercourse: Compared with the 1991 Sapporo Survey, the proportion of men reporting sexual intercourse less than once per month was significantly higher across all age groups in the 2023 Nationwide Survey, except among men in their 20s. 2. Penile rigidity: The proportion of men with insufficient penile rigidity for penetration was significantly higher in 2023 than in 1991 across all age groups except those aged ≥ 75 years. 3. Morning erections: Men reporting complete absence of morning erections were significantly more common in 2023 across all age groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Over the past three decades, Japanese men have shown substantial declines in the frequency of sexual intercourse, penile rigidity, and the frequency of morning erections, particularly in younger and middle-aged cohorts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment on Oligometastatic Prostate and Bladder Cancer: An Integrative Narrative Review","authors":"Hiroshi Hirata","doi":"10.1111/iju.70343","DOIUrl":"10.1111/iju.70343","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment on “Usefulness of the Toronto Voiding Symptom Score in the Diagnosis of Occult Tethered Cord Syndrome”","authors":"Ismail Selvi","doi":"10.1111/iju.70349","DOIUrl":"10.1111/iju.70349","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment to “Clinical Features and Risk Factors of Enfortumab Vedotin-Induced Peripheral Neuropathy in Patients With Metastatic Urothelial Carcinoma: A Multicenter Retrospective Study (YUSHIMA Study)”","authors":"Makito Miyake","doi":"10.1111/iju.70351","DOIUrl":"10.1111/iju.70351","url":null,"abstract":"","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vesicourethral anastomotic stenosis and/or urethral stenosis (VUAS/US) is a complication of robotic-assisted radical prostatectomy (RARP) for prostate cancer. We aimed to evaluate the incidence of VUAS/US after RARP and to identify potential risk factors.
Materials and Methods
We performed a retrospective assessment of clinical records of patients with RARP as primary prostate cancer treatment (January 2011–December 2018) and investigated associations between VUAS/US formation and radiotherapy, pT-stage, tumor margins, Gleason score, nerve-sparing, and postoperative duration of bladder catheterization. Statistical analysis was performed via uni- and multivariable cox regression; risk estimation was done with the Kaplan–Meier method and log-rank test.
Results and Limitations
809 patients were included in the study. Median clinical follow-up was 61.0 months (IQR 50.0–75.0) and 175 (22%) patients received radiotherapy. VUAS and US were recorded in 19 (2.3%) and 10 (1.2%) patients, respectively. Whereas in univariable analysis radiotherapy, pT-stage ≥ pT3a, higher Gleason score, positive tumor margins, nerve-sparing, and prolonged duration of bladder catheterization were significant risk factors, in a multivariable analysis only radiotherapy (p = 0.003) and prolonged duration of bladder catheterization (p = 0.0309) proved to be independently predictive. Estimated 5-year risk of VUAS/US formation was lower without than with radiotherapy (2.1% [95% CI: 0.9–3.3] vs. 7.3% [95% CI: 3.4–11]) and with normal compared to prolonged bladder catheterization (2.6% [95% CI: 1.4–3.8] vs. 9.9% [95% CI: 2.3–18]). Retrospectivity and the limited number of events were our major limitations.
Conclusions and Clinical Implications
Low incidence of VUAS/US in RARP. Patients undergoing radiotherapy or requiring prolonged catheterization should be explicitly informed about the risk of VUAS/US and about symptoms. Also, physicians must be aware.
{"title":"Retrospective Analysis of Vesicourethral-Anastomosis Stricture/Urethral Stricture After Robotic-Assisted Laparoscopic Radical Prostatectomy With and Without Radiotherapy","authors":"Kinan Massouh, Katharina Leucht, Lutz Leistritz, Marc-Oliver Grimm","doi":"10.1111/iju.70339","DOIUrl":"10.1111/iju.70339","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objective</h3>\u0000 \u0000 <p>Vesicourethral anastomotic stenosis and/or urethral stenosis (VUAS/US) is a complication of robotic-assisted radical prostatectomy (RARP) for prostate cancer. We aimed to evaluate the incidence of VUAS/US after RARP and to identify potential risk factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>We performed a retrospective assessment of clinical records of patients with RARP as primary prostate cancer treatment (January 2011–December 2018) and investigated associations between VUAS/US formation and radiotherapy, pT-stage, tumor margins, Gleason score, nerve-sparing, and postoperative duration of bladder catheterization. Statistical analysis was performed via uni- and multivariable cox regression; risk estimation was done with the Kaplan–Meier method and log-rank test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results and Limitations</h3>\u0000 \u0000 <p>809 patients were included in the study. Median clinical follow-up was 61.0 months (IQR 50.0–75.0) and 175 (22%) patients received radiotherapy. VUAS and US were recorded in 19 (2.3%) and 10 (1.2%) patients, respectively. Whereas in univariable analysis radiotherapy, pT-stage ≥ pT3a, higher Gleason score, positive tumor margins, nerve-sparing, and prolonged duration of bladder catheterization were significant risk factors, in a multivariable analysis only radiotherapy (<i>p</i> = 0.003) and prolonged duration of bladder catheterization (<i>p</i> = 0.0309) proved to be independently predictive. Estimated 5-year risk of VUAS/US formation was lower without than with radiotherapy (2.1% [95% CI: 0.9–3.3] vs. 7.3% [95% CI: 3.4–11]) and with normal compared to prolonged bladder catheterization (2.6% [95% CI: 1.4–3.8] vs. 9.9% [95% CI: 2.3–18]). Retrospectivity and the limited number of events were our major limitations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Implications</h3>\u0000 \u0000 <p>Low incidence of VUAS/US in RARP. Patients undergoing radiotherapy or requiring prolonged catheterization should be explicitly informed about the risk of VUAS/US and about symptoms. Also, physicians must be aware.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14323,"journal":{"name":"International Journal of Urology","volume":"33 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iju.70339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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