首页 > 最新文献

International Surgery Journal最新文献

英文 中文
Rectal malakoplakia simulating a locally advanced rectal cancer: a case report 模拟局部晚期直肠癌的直肠恶性肿瘤:一份病例报告
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240757
André A. Silva, Guida C. Pires, Liliana V. Simões, Beatriz R. Lourenço, Catarina C. Rocha, Lília J. Meireles
Malakoplakia is a rare and chronic granulomatous disease, resulting from the accumulation of large granular macrophages containing basophilic inclusion bodies in the cytoplasm named Michaelis-Gutmann bodies. The gastrointestinal tract is the second most common site after the urinary tract, though malakoplakia has the potential to manifest in multiple organs. Rectal malakoplakia is difficult to diagnose due to its unspecific clinical and radiological presentation, usually mimicking a malignancy. Most report cases are associated with immunosuppressive diseases or chronic prolonged illness. We present the case of a 64-year-old male with a history of anal pain. A pelvic magnetic resonance imaging showed a rectal mass with 38 mm invading the mesorectum. Colonoscopy was performed confirming a mass-like lesion and biopsies were taken. Histopathological examination revealed features consistent with malakoplakia. The patient underwent long-term oral antibiotic treatment and during follow-up there was a regression of the lesion and resolution of symptoms.
麦拉克氏病是一种罕见的慢性肉芽肿性疾病,由胞质中含有嗜碱性包涵体的大颗粒巨噬细胞堆积而成,这种包涵体被命名为麦拉克氏-古特曼体(Michaelis-Gutmann bodies)。胃肠道是仅次于泌尿道的第二大常见部位,但恶性肿瘤有可能在多个器官出现。直肠恶性肿瘤很难诊断,因为它的临床和影像学表现没有特异性,通常会模仿恶性肿瘤。大多数报告病例与免疫抑制性疾病或长期慢性疾病有关。我们报告的病例是一名 64 岁的男性,有肛门疼痛病史。盆腔磁共振成像显示有一个 38 毫米的直肠肿块侵入直肠中层。结肠镜检查证实了肿块样病变,并进行了活检。组织病理学检查显示其特征与恶性肿瘤一致。患者接受了长期口服抗生素治疗,随访期间病灶消退,症状缓解。
{"title":"Rectal malakoplakia simulating a locally advanced rectal cancer: a case report","authors":"André A. Silva, Guida C. Pires, Liliana V. Simões, Beatriz R. Lourenço, Catarina C. Rocha, Lília J. Meireles","doi":"10.18203/2349-2902.isj20240757","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240757","url":null,"abstract":"Malakoplakia is a rare and chronic granulomatous disease, resulting from the accumulation of large granular macrophages containing basophilic inclusion bodies in the cytoplasm named Michaelis-Gutmann bodies. The gastrointestinal tract is the second most common site after the urinary tract, though malakoplakia has the potential to manifest in multiple organs. Rectal malakoplakia is difficult to diagnose due to its unspecific clinical and radiological presentation, usually mimicking a malignancy. Most report cases are associated with immunosuppressive diseases or chronic prolonged illness. We present the case of a 64-year-old male with a history of anal pain. A pelvic magnetic resonance imaging showed a rectal mass with 38 mm invading the mesorectum. Colonoscopy was performed confirming a mass-like lesion and biopsies were taken. Histopathological examination revealed features consistent with malakoplakia. The patient underwent long-term oral antibiotic treatment and during follow-up there was a regression of the lesion and resolution of symptoms.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"24 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140373701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of extra adrenal retroperitoneal paraganglioma: case report 肾上腺外腹膜后副神经节瘤:罕见病例报告
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240754
Sakshi Ramnani, Subhash Chawla, M. S. Utaal, Mrigendra Singh, Dakshita Adlakha, Mrugen Thakor
Extra adrenal retroperitoneal paragangliomas are neuro endocrine neoplasms with extremely rare incidence and a wide plethora of clinical presentations. They originate from the neural crest cells interspersed throughout the body. They can present with vague symptoms of pain abdomen, hypertension, palpitations and in severe cases with renal failure, and shock owing to catecholamine excess. On the other end of the spectrum they can be totally asymptomatic and detected incidentally. The multitude of clinical presentations and lack of specific diagnostic tests hence pose a great difficulty in the pre-operative diagnosis of the disease. We are presenting a case of a 20-year-old female with vague symptoms to highlight the management and clinical diagnosis of extra adrenal retroperitoneal paraganglioma. 
肾上腺后腹膜外副神经节瘤是一种神经内分泌肿瘤,发病率极低,临床表现多种多样。它们起源于遍布全身的神经嵴细胞。它们可表现为腹部疼痛、高血压、心悸等模糊症状,严重者可因儿茶酚胺过多而导致肾功能衰竭和休克。另一方面,它们也可能完全没有症状,只是偶然被发现。由于临床表现多种多样,且缺乏特异性诊断测试,因此给该病的术前诊断带来了很大困难。我们将介绍一例症状模糊的 20 岁女性病例,以强调肾上腺外腹膜后副神经节瘤的处理和临床诊断。
{"title":"A rare case of extra adrenal retroperitoneal paraganglioma: case report","authors":"Sakshi Ramnani, Subhash Chawla, M. S. Utaal, Mrigendra Singh, Dakshita Adlakha, Mrugen Thakor","doi":"10.18203/2349-2902.isj20240754","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240754","url":null,"abstract":"Extra adrenal retroperitoneal paragangliomas are neuro endocrine neoplasms with extremely rare incidence and a wide plethora of clinical presentations. They originate from the neural crest cells interspersed throughout the body. They can present with vague symptoms of pain abdomen, hypertension, palpitations and in severe cases with renal failure, and shock owing to catecholamine excess. On the other end of the spectrum they can be totally asymptomatic and detected incidentally. The multitude of clinical presentations and lack of specific diagnostic tests hence pose a great difficulty in the pre-operative diagnosis of the disease. We are presenting a case of a 20-year-old female with vague symptoms to highlight the management and clinical diagnosis of extra adrenal retroperitoneal paraganglioma.\u0000 ","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"04 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caesarean section scar pregnancy: a case series 剖腹产瘢痕妊娠:病例系列
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240752
Tan Ying An, K. Nagandla, Krishna Kumar, Akshatha Daniel
Cesarean scar pregnancy is a rare type of ectopic pregnancy but potentially life threatening. The incidence of this ectopic pregnancy continues to rise due to global increase in cesarean sections rates as well as the diagnosis with wide use of transvaginal ultrasound. Delay or wrong diagnosis may result to uterine rupture and life-threatening bleeding with potential maternal morbidity and mortality.  Endo-vaginal ultrasound has a reported sensitivity of 85-90% for detection. In difficult cases, magnetic resonance imaging is often useful as second line imaging. Treatment may be ranging from conservative to medical therapy or surgery. We present a series of three illustrative cases successfully managed with medical management and sequential treatment of medical and surgical management. We discuss diagnostic challenges and review of literature on updates on management strategies.
剖宫产瘢痕妊娠是一种罕见的异位妊娠,但可能危及生命。由于全球剖宫产率的增加以及经阴道超声诊断的广泛应用,这种异位妊娠的发病率持续上升。延误或错误的诊断可能会导致子宫破裂和危及生命的大出血,并造成潜在的孕产妇发病率和死亡率。 据报道,阴道内超声检查的灵敏度为 85%-90%。在疑难病例中,磁共振成像通常可作为第二线成像。治疗方法包括保守治疗、药物治疗或手术治疗。我们介绍了三个成功接受药物治疗以及药物和手术治疗的病例。我们将讨论诊断方面的挑战,并回顾有关最新治疗策略的文献。
{"title":"Caesarean section scar pregnancy: a case series","authors":"Tan Ying An, K. Nagandla, Krishna Kumar, Akshatha Daniel","doi":"10.18203/2349-2902.isj20240752","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240752","url":null,"abstract":"Cesarean scar pregnancy is a rare type of ectopic pregnancy but potentially life threatening. The incidence of this ectopic pregnancy continues to rise due to global increase in cesarean sections rates as well as the diagnosis with wide use of transvaginal ultrasound. Delay or wrong diagnosis may result to uterine rupture and life-threatening bleeding with potential maternal morbidity and mortality.  Endo-vaginal ultrasound has a reported sensitivity of 85-90% for detection. In difficult cases, magnetic resonance imaging is often useful as second line imaging. Treatment may be ranging from conservative to medical therapy or surgery. We present a series of three illustrative cases successfully managed with medical management and sequential treatment of medical and surgical management. We discuss diagnostic challenges and review of literature on updates on management strategies.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the use habits and efficacy of intracavernosal alprostadil: is it tolerable and sustainable? 评估阴茎海绵体内阿洛前列地尔的使用习惯和疗效:它是否可以忍受和持续?
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240749
Mehmet G. Sönmez, Eren Erol, Leyla Ö. Sönmez, Arif Aydın
Background: The aim of this study was to evaluate the efficacy of intracavernosal alprostadil treatment for erectile dysfunction and the evaluation of factors such as ease of drug use, duration of use, and difficulties in habituation.Methods: The data of 40 patients who were treated for erectile dysfunction, had inadequate response from first-line treatment modalities, received intracavernosal alprostadil in second-line treatment and continued treatment for more than 12 weeks without interruption were analyzed. Sexual function status was evaluated by 15-question international ındex of erectile function (IIEF-15) form and degree of erection (1-10 points). In addition, duration of use, self-administered dose, reasons for difficulty, and reasons for treatment interruption were investigated.Results: The mean duration of use was 21.38 months. Patients switched to self-administration after an average minimum dose of 2.23 doses. After 12 weeks, 50% of the patients discontinued self-administration, 10% because of difficulty in administration, 55% because of inadequate erection response, 25% because of time, and 10% because of additional health problems. IIEF-15 parameters and the degree of erection were found to improve significantly after administration (p<0.05 for all parameters).Conclusions: Intracavernosal alprostadil provides significant improvement in sexual function, but since it is an invasive application, patients have difficulty in getting used to it, self-administration is started after a minimum of 2 doses, and the reason for discontinuation is mostly due to inadequate erectile response.
研究背景本研究的目的是评估阴茎海绵体内注射阿洛前列地尔治疗勃起功能障碍的疗效,以及评估药物使用的难易程度、使用时间和习惯困难等因素:分析了40名接受勃起功能障碍治疗的患者的数据,这些患者对一线治疗方法反应不佳,在二线治疗中接受了阴茎海绵体内注射阿咯司他地治疗,并持续治疗12周以上,没有中断过治疗。性功能状况通过 15 个问题的国际勃起功能指数(IIEF-15)表和勃起程度(1-10 分)进行评估。此外,还调查了用药时间、自行用药剂量、用药困难的原因以及中断治疗的原因:结果:平均用药时间为 21.38 个月。患者在平均服用 2.23 次最低剂量后转为自行用药。12 周后,50% 的患者中断了自行用药,10% 是因为用药困难,55% 是因为勃起反应不足,25% 是因为时间问题,10% 是因为其他健康问题。用药后,IIEF-15 参数和勃起程度均有明显改善(所有参数的 P<0.05 ):结论:阴茎海绵体内注射阿普斯地尔能显著改善性功能,但由于这是一种侵入性用药,患者很难适应,至少要在用药 2 次后才能开始自行用药,停药的原因主要是勃起反应不足。
{"title":"Assessing the use habits and efficacy of intracavernosal alprostadil: is it tolerable and sustainable?","authors":"Mehmet G. Sönmez, Eren Erol, Leyla Ö. Sönmez, Arif Aydın","doi":"10.18203/2349-2902.isj20240749","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240749","url":null,"abstract":"Background: The aim of this study was to evaluate the efficacy of intracavernosal alprostadil treatment for erectile dysfunction and the evaluation of factors such as ease of drug use, duration of use, and difficulties in habituation.\u0000Methods: The data of 40 patients who were treated for erectile dysfunction, had inadequate response from first-line treatment modalities, received intracavernosal alprostadil in second-line treatment and continued treatment for more than 12 weeks without interruption were analyzed. Sexual function status was evaluated by 15-question international ındex of erectile function (IIEF-15) form and degree of erection (1-10 points). In addition, duration of use, self-administered dose, reasons for difficulty, and reasons for treatment interruption were investigated.\u0000Results: The mean duration of use was 21.38 months. Patients switched to self-administration after an average minimum dose of 2.23 doses. After 12 weeks, 50% of the patients discontinued self-administration, 10% because of difficulty in administration, 55% because of inadequate erection response, 25% because of time, and 10% because of additional health problems. IIEF-15 parameters and the degree of erection were found to improve significantly after administration (p<0.05 for all parameters).\u0000Conclusions: Intracavernosal alprostadil provides significant improvement in sexual function, but since it is an invasive application, patients have difficulty in getting used to it, self-administration is started after a minimum of 2 doses, and the reason for discontinuation is mostly due to inadequate erectile response.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"8 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Principles of dressing and debridement in modern rural surgery: experience of a case of Fournier’s gangrene 现代农村外科的包扎和清创原则:一例 Fournier 坏疽病例的经验
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240763
Arijit Rumu Baruah, Darpana Kalita
Fournier’s gangrene is a rare and rapidly progressive necrotising fasciitis of the external genitalia and perineum. It is characterised by obliterative endarteritis of the subcutaneous arteries resulting in gangrene of the subcutaneous tissue and the overlying skin. Rural surgery refers to the practice of surgery serving people in rural communities and geographically remote areas. Rural surgery faces multiple challenges like limitation of resources and manpower, poverty, multiple co-morbidities and superstitions. We present such a case of Fournier’s gangrene treated in a secondary care centre of rural Assam. A 45 year old male presented with pain and discharge from the scrotum since two weeks. No other co-morbidities were present. Initially, wound debridement and dressing with hydrogen peroxide and povidone iodine is done. Necrosed tissue is sent for microbial culture and sensitivity. Initially, empirical antibiotics was started and was converted to fluoroquinolones as it showed sensitivity. Serial dressing and debridement were continued till healthy granulation tissue appeared. Then, the wound was closed by loose approximation method. Wound was successfully apposed and viability of both the testis was also found to be intact. Thus, the age-old principle of dressing and debridement still serves as the background of wound care in modern rural surgery.
福尼尔坏疽是一种罕见的、进展迅速的外生殖器和会阴部坏死性筋膜炎。其特点是皮下动脉发生闭塞性动脉内膜炎,导致皮下组织和上覆皮肤坏疽。农村外科是指为农村社区和地理偏远地区的人们提供服务的外科手术。农村外科面临着资源和人力限制、贫困、多种并发症和迷信等多重挑战。我们在阿萨姆邦农村地区的一家二级医疗中心介绍了这样一例治疗 Fournier 坏疽的病例。患者为一名 45 岁男性,两周前开始出现阴囊疼痛和分泌物增多。无其他并发症。最初,医生用双氧水和聚维酮碘对伤口进行清创和包扎。坏死组织被送去进行微生物培养和药敏试验。起初使用的是经验性抗生素,后因显示出敏感性而改用氟喹诺酮类药物。连续敷料和清创一直持续到健康的肉芽组织出现。然后,采用松弛贴近法缝合伤口。伤口成功贴合,两个睾丸的存活能力也完好无损。因此,包扎和清创这一古老的原则仍然是现代农村外科伤口护理的基础。
{"title":"Principles of dressing and debridement in modern rural surgery: experience of a case of Fournier’s gangrene","authors":"Arijit Rumu Baruah, Darpana Kalita","doi":"10.18203/2349-2902.isj20240763","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240763","url":null,"abstract":"Fournier’s gangrene is a rare and rapidly progressive necrotising fasciitis of the external genitalia and perineum. It is characterised by obliterative endarteritis of the subcutaneous arteries resulting in gangrene of the subcutaneous tissue and the overlying skin. Rural surgery refers to the practice of surgery serving people in rural communities and geographically remote areas. Rural surgery faces multiple challenges like limitation of resources and manpower, poverty, multiple co-morbidities and superstitions. We present such a case of Fournier’s gangrene treated in a secondary care centre of rural Assam. A 45 year old male presented with pain and discharge from the scrotum since two weeks. No other co-morbidities were present. Initially, wound debridement and dressing with hydrogen peroxide and povidone iodine is done. Necrosed tissue is sent for microbial culture and sensitivity. Initially, empirical antibiotics was started and was converted to fluoroquinolones as it showed sensitivity. Serial dressing and debridement were continued till healthy granulation tissue appeared. Then, the wound was closed by loose approximation method. Wound was successfully apposed and viability of both the testis was also found to be intact. Thus, the age-old principle of dressing and debridement still serves as the background of wound care in modern rural surgery.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"97 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extrahepatic and extrapulmonary hydatid cysts as primary lesions 作为原发病灶的肝外和肺外水瘤囊肿
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240750
Hepi V. Patel, Dharmesh P. Vasavada
Background: Hydatid cyst disease, caused by the larval stage of the parasite Echinococcus granulosus, commonly affects the liver and lungs but can also manifest in various extrahepatic and extrapulmonary locations. Splenic hydatid disease, despite being rare, is the third most common location. This paper presents a case series highlighting the clinical presentation, diagnostic challenges, and management strategies for patients with extrahepatic and extrapulmonary hydatid cysts. Several studies already postulated on sites of hydatid cysts which have statistically significant results.Methods: Patients who were operated on for hydatid disease or cystic lesions, which were later diagnosed as hydatid disease, between September 2022-August 2023 were retrieved retrospectively. Patients with lesions localized outside the liver and the lung as well as in liver and lung were enrolled in the study. Fifty-Two patients with extra-hepatic primary hydatid disease were treated surgically at our clinic. The cysts were located in different part of body. Results has undergone statistical methods like Z-test and Mann-Whitney U test. Any patient of any gender admitted with diagnosis of hydatid cyst in any part of body with age >18 but less than 70 years irrespective of any comorbidities.Results: Surgical techniques like partial or total cystectomy with or without tube drainage are good option for management of extrahepatic and extrapulmonary primary hydatid cysts. There were no complications or mortality in the postoperative period. Hydatid cyst is considered in the differential diagnosis of cystic lesions, especially in endemic areas. Surgical technique planned according to the location of the cyst.Conclusions: Cystectomy is a surgical option in extrahepatic and extrapulmonary hydatid cyst which is evaluate better in this study. 
背景:由棘球蚴幼虫阶段引起的包虫囊肿病通常会影响肝脏和肺部,但也可表现为肝外和肺外的各种部位。脾包虫病虽然罕见,但却是第三大常见病发部位。本文通过一系列病例着重介绍了肝外和肺外包虫囊肿患者的临床表现、诊断难题和治疗策略。已有多项研究推测了水瘤囊肿的发病部位,并得出了具有统计学意义的结果:方法:回顾性检索 2022 年 9 月至 2023 年 8 月期间因包虫病或囊性病变接受手术的患者,这些患者后来被诊断为包虫病。病变位于肝脏和肺脏以外以及肝脏和肺脏内的患者均被纳入研究。52 名肝外原发性包虫病患者在本诊所接受了手术治疗。囊肿位于身体的不同部位。研究结果采用 Z 检验和 Mann-Whitney U 检验等统计方法。任何性别、年龄大于 18 岁但小于 70 岁、被诊断为身体任何部位的包虫囊肿患者,无论是否有任何合并症:肝外和肺外原发性包虫囊肿的治疗方法中,部分或全部囊肿切除术(带或不带管道引流)是不错的选择。术后无并发症或死亡率。在囊性病变的鉴别诊断中应考虑包虫囊肿,尤其是在地方病流行地区。根据囊肿的位置规划手术技术:囊肿切除术是肝外和肺外包虫囊肿的一种手术选择,在本研究中得到了较好的评价。
{"title":"Extrahepatic and extrapulmonary hydatid cysts as primary lesions","authors":"Hepi V. Patel, Dharmesh P. Vasavada","doi":"10.18203/2349-2902.isj20240750","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240750","url":null,"abstract":"Background: Hydatid cyst disease, caused by the larval stage of the parasite Echinococcus granulosus, commonly affects the liver and lungs but can also manifest in various extrahepatic and extrapulmonary locations. Splenic hydatid disease, despite being rare, is the third most common location. This paper presents a case series highlighting the clinical presentation, diagnostic challenges, and management strategies for patients with extrahepatic and extrapulmonary hydatid cysts. Several studies already postulated on sites of hydatid cysts which have statistically significant results.\u0000Methods: Patients who were operated on for hydatid disease or cystic lesions, which were later diagnosed as hydatid disease, between September 2022-August 2023 were retrieved retrospectively. Patients with lesions localized outside the liver and the lung as well as in liver and lung were enrolled in the study. Fifty-Two patients with extra-hepatic primary hydatid disease were treated surgically at our clinic. The cysts were located in different part of body. Results has undergone statistical methods like Z-test and Mann-Whitney U test. Any patient of any gender admitted with diagnosis of hydatid cyst in any part of body with age >18 but less than 70 years irrespective of any comorbidities.\u0000Results: Surgical techniques like partial or total cystectomy with or without tube drainage are good option for management of extrahepatic and extrapulmonary primary hydatid cysts. There were no complications or mortality in the postoperative period. Hydatid cyst is considered in the differential diagnosis of cystic lesions, especially in endemic areas. Surgical technique planned according to the location of the cyst.\u0000Conclusions: Cystectomy is a surgical option in extrahepatic and extrapulmonary hydatid cyst which is evaluate better in this study.\u0000 ","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"93 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Need for a paradigm shift? Survival post-pancreatoduodenectomy remains poor despite surgical and oncological advances 是否需要转变模式?胰十二指肠切除术后的存活率仍然很低,尽管手术和肿瘤学取得了进步
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240748
Mia Shepherdson, Daniel Kilburn, Matthew Marshall-Webb, Shahid Ullah, John Chen, M. Brooke-Smith
Background: Despite advances in surgical techniques and chemotherapy, poor outcomes persist in pancreatic malignancy. This study aimed to investigate clinical outcomes and describe the impact of factors like the closest resection margin on overall survival following open pancreatoduodenectomy at a tertiary referral centre over a ten-year period.Methods: Patients who underwent a pancreaticoduodenectomy at a tertiary hospital in South Australia between 2009-2019 were included in this retrospective study. Patient demographics, systemic treatments, complications, and histological features were analysed for their role in overall survival. Kaplan-Meier survival curves were used to assess patient survival and estimate median survival time.Results: There were 134 open pancreaticoduodenectomy procedures during 2009-2019. Majority of patients were male (54.7%) between 65-75 years of age (41%) with an ASA physical status classification grade of 3 (63.3%). 56.7% of patients experienced a complication with 5 in-hospital deaths recorded and 12 ISPGF grade B or C pancreatic anastomotic leaks (n=5, n=7 respectively). 88% of resected specimens were malignant with an overall 5-year survival of 32%. A resection margin of >2 mm had a significantly improved overall survival compared to 0 mm (p=0.01). There was no survival benefit for a resection margin of <1 mm or 1-2 mm compared 0mm margin (p=0.6 and p=0.2 respectively). 65 patients (54.6%) experienced either local or distal disease recurrence by the end of the study period.Conclusions: There has been no improvement in overall survival post pancreatoduodenectomy for pancreatic malignancy. Further research into the clinical significance of the R status classification is required.
背景:尽管外科技术和化疗取得了进步,但胰腺恶性肿瘤的治疗效果仍然不佳。本研究旨在调查临床结果,并描述十年间三级转诊中心开放式胰十二指肠切除术后最接近切除边缘等因素对总生存率的影响:这项回顾性研究纳入了2009-2019年间在南澳大利亚州一家三级医院接受胰十二指肠切除术的患者。研究分析了患者的人口统计学特征、系统治疗、并发症和组织学特征对总生存率的影响。采用卡普兰-梅耶生存曲线评估患者生存率并估算中位生存时间:2009-2019年期间,共有134例开腹胰十二指肠切除术。大多数患者为男性(54.7%),年龄在 65-75 岁之间(41%),ASA 身体状况分类等级为 3 级(63.3%)。56.7%的患者出现并发症,其中5例患者在院内死亡,12例患者出现ISPGF B级或C级胰腺吻合口漏(分别为5例和7例)。88%的切除标本为恶性,5年总存活率为32%。切除边缘大于 2 毫米的总生存率明显高于 0 毫米(P=0.01)。切除边缘小于1毫米或1-2毫米与0毫米边缘相比,生存率没有提高(分别为P=0.6和P=0.2)。65名患者(54.6%)在研究结束时出现局部或远端疾病复发:结论:胰腺恶性肿瘤胰十二指肠切除术后的总生存率没有提高。需要进一步研究R状态分类的临床意义。
{"title":"Need for a paradigm shift? Survival post-pancreatoduodenectomy remains poor despite surgical and oncological advances","authors":"Mia Shepherdson, Daniel Kilburn, Matthew Marshall-Webb, Shahid Ullah, John Chen, M. Brooke-Smith","doi":"10.18203/2349-2902.isj20240748","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240748","url":null,"abstract":"Background: Despite advances in surgical techniques and chemotherapy, poor outcomes persist in pancreatic malignancy. This study aimed to investigate clinical outcomes and describe the impact of factors like the closest resection margin on overall survival following open pancreatoduodenectomy at a tertiary referral centre over a ten-year period.\u0000Methods: Patients who underwent a pancreaticoduodenectomy at a tertiary hospital in South Australia between 2009-2019 were included in this retrospective study. Patient demographics, systemic treatments, complications, and histological features were analysed for their role in overall survival. Kaplan-Meier survival curves were used to assess patient survival and estimate median survival time.\u0000Results: There were 134 open pancreaticoduodenectomy procedures during 2009-2019. Majority of patients were male (54.7%) between 65-75 years of age (41%) with an ASA physical status classification grade of 3 (63.3%). 56.7% of patients experienced a complication with 5 in-hospital deaths recorded and 12 ISPGF grade B or C pancreatic anastomotic leaks (n=5, n=7 respectively). 88% of resected specimens were malignant with an overall 5-year survival of 32%. A resection margin of >2 mm had a significantly improved overall survival compared to 0 mm (p=0.01). There was no survival benefit for a resection margin of <1 mm or 1-2 mm compared 0mm margin (p=0.6 and p=0.2 respectively). 65 patients (54.6%) experienced either local or distal disease recurrence by the end of the study period.\u0000Conclusions: There has been no improvement in overall survival post pancreatoduodenectomy for pancreatic malignancy. Further research into the clinical significance of the R status classification is required.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"46 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140376912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic hydatid cyst: a case report 脾包虫囊肿:病例报告
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240753
Dakshita Adlakha, Subhash Chawla, M. S. Utaal, Shivam Sharma, Ankita Khurana, Mrugen Thakor, Sakshi Ramnani
Hydatid cyst (HD) disease is a parasitic infection caused by Echinococcus granulosus. It occurs worldwide, but its prevalence is higher in the rural communities where sheep and cattle raising constitute a crucial component of the agricultural industry. This is a zoonotic disease which spreads via close contact of humans with sheep and dogs. The most common organs involved in hydatid cyst are the liver and lungs. However, other organs may also foster it, such as the spleen which is a rare clinical condition, with an incidence rate of between 0.5% and 4%. In this study, a 46-year-old male with a primary splenic HC is reported with chief complaint of pain and non-tender palpable mass in left hypochondrium. A 9.7×10.6×11 cm splenic cystic mass was detected on ultrasonography (US) and confirmed by abdominal computed tomography (CT) scan, without involvement of other organs. Splenectomy was done along with excision of intact hydatid cyst. Pathological examinations revealed cystic hydatidosis. We describe this case of an isolated splenic HC, which was successfully treated with total splenectomy, focusing on the management and outcome of this disease.
包虫囊肿病(HD)是一种由棘球蚴引起的寄生虫感染。这种疾病在世界各地都有发生,但在农村社区发病率较高,因为养羊和养牛是农业产业的重要组成部分。这是一种人畜共患病,通过人与羊和狗的密切接触传播。包虫囊肿最常涉及的器官是肝脏和肺部。不过,其他器官也可能感染,例如脾脏,这是一种罕见的临床病症,发病率在 0.5% 到 4% 之间。在本研究中,报告了一名 46 岁男性原发性脾脏 HC 患者,主诉为左侧下腹疼痛并可触及无触痛的肿块。超声波检查(US)发现一个 9.7×10.6×11 厘米的脾脏囊性肿块,腹部计算机断层扫描(CT)证实该肿块未累及其他器官。在切除完整水瘤囊肿的同时进行了脾切除术。病理检查显示为囊性包虫病。我们描述了这例通过全脾切除术成功治疗的孤立性脾包虫病,重点介绍了这种疾病的治疗方法和结果。
{"title":"Splenic hydatid cyst: a case report","authors":"Dakshita Adlakha, Subhash Chawla, M. S. Utaal, Shivam Sharma, Ankita Khurana, Mrugen Thakor, Sakshi Ramnani","doi":"10.18203/2349-2902.isj20240753","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240753","url":null,"abstract":"Hydatid cyst (HD) disease is a parasitic infection caused by Echinococcus granulosus. It occurs worldwide, but its prevalence is higher in the rural communities where sheep and cattle raising constitute a crucial component of the agricultural industry. This is a zoonotic disease which spreads via close contact of humans with sheep and dogs. The most common organs involved in hydatid cyst are the liver and lungs. However, other organs may also foster it, such as the spleen which is a rare clinical condition, with an incidence rate of between 0.5% and 4%. In this study, a 46-year-old male with a primary splenic HC is reported with chief complaint of pain and non-tender palpable mass in left hypochondrium. A 9.7×10.6×11 cm splenic cystic mass was detected on ultrasonography (US) and confirmed by abdominal computed tomography (CT) scan, without involvement of other organs. Splenectomy was done along with excision of intact hydatid cyst. Pathological examinations revealed cystic hydatidosis. We describe this case of an isolated splenic HC, which was successfully treated with total splenectomy, focusing on the management and outcome of this disease.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"43 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive case study of cholecystectomy in a patient with a gallbladder laden with 442 stones 对一名胆囊充满 442 颗结石的患者进行胆囊切除术的综合病例研究
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240761
Prashant Kedari, Milind Joshi, Vaibhav Kapoor, Sushant Khurana
Cholelithiasis (gallstones), crystalline formations in the gallbladder, presents a common yet intricate medical concern. These stones can vary in size and composition, ranging from cholesterol to pigment-based stones. Treatment often involves surgical intervention, with laparoscopic procedures being a minimally invasive and effective option. However, complications arise when multiple stones are present, leading to heightened inflammation and recurrent symptoms. In this study, we present a case of a 34-year-old, male who came with complaints of abdominal pain and bloating, intermittent nausea, vomiting, and jaundice for more than 5 days. He was diagnosed with multiple calculi in the gallbladder (acute cholecystitis with cholelithiasis) based on ultrasonography. Since the patient had jaundice, he was suggested to get a magnetic resonance cholangiopancreatography (MRCP) to rule out any pathoanatomy. He received treatment by laparoscopic cholecystectomy and showed improvement within 5 days of surgery.
胆石症(胆结石)是胆囊中的结晶体,是一种常见而又复杂的医学问题。这些结石的大小和成分各不相同,有胆固醇结石,也有色素结石。治疗通常涉及手术干预,腹腔镜手术是一种微创而有效的选择。然而,当出现多发性结石时,就会出现并发症,导致炎症加重和症状反复。在本研究中,我们介绍了一例 34 岁的男性患者,他主诉腹痛、腹胀、间歇性恶心、呕吐和黄疸超过 5 天。根据超声波检查,他被诊断为胆囊多发性结石(急性胆囊炎伴胆石症)。由于患者出现黄疸,医生建议他进行磁共振胆胰管造影(MRCP),以排除任何病理解剖。他接受了腹腔镜胆囊切除术治疗,术后 5 天内病情有所好转。
{"title":"A comprehensive case study of cholecystectomy in a patient with a gallbladder laden with 442 stones","authors":"Prashant Kedari, Milind Joshi, Vaibhav Kapoor, Sushant Khurana","doi":"10.18203/2349-2902.isj20240761","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240761","url":null,"abstract":"Cholelithiasis (gallstones), crystalline formations in the gallbladder, presents a common yet intricate medical concern. These stones can vary in size and composition, ranging from cholesterol to pigment-based stones. Treatment often involves surgical intervention, with laparoscopic procedures being a minimally invasive and effective option. However, complications arise when multiple stones are present, leading to heightened inflammation and recurrent symptoms. In this study, we present a case of a 34-year-old, male who came with complaints of abdominal pain and bloating, intermittent nausea, vomiting, and jaundice for more than 5 days. He was diagnosed with multiple calculi in the gallbladder (acute cholecystitis with cholelithiasis) based on ultrasonography. Since the patient had jaundice, he was suggested to get a magnetic resonance cholangiopancreatography (MRCP) to rule out any pathoanatomy. He received treatment by laparoscopic cholecystectomy and showed improvement within 5 days of surgery.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"17 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin graft on a collagen and elastin matrix fixed with negative pressure in a complicated pediatric dog bite: case report 在用负压固定的胶原蛋白和弹性蛋白基质上植皮治疗复杂的小儿被狗咬伤:病例报告
Pub Date : 2024-03-27 DOI: 10.18203/2349-2902.isj20240755
Omar S. Fattel-Servin, Osvaldo I. Guevara-Valmaña, Sebastian Trigueiros-Guzmán, Valentina Prieto-Vargas, Ximena I. Ramirez-Morales, Armando Apellaniz-campo
Animal bites represent a significant source of morbidity in the pediatric population, with dogs being the primary cause. Highlighting the need for innovative solutions to effectively tackle the issue and enhance both functional and aesthetic outcomes. Dog bites, marked by a heightened morbidity rate, present an inherent infection risk owing to the considerable bacterial load present in saliva. The fundamental approach to treatment revolves around preventing infection through meticulous washing, debridement, and the timely implementation of early primary closure. We detail the management of a pediatric patient with a dog bite on the pelvic limb, resulting in a challenging-to-manage wound. This case was successfully treated with a skin graft on a bed of collagen matrix, secured with negative pressure therapy. The choice of the appropriate technique for reconstructing skin defects depends on their depth and size. Consequently, combining these three techniques yielded a favorable functional and aesthetic outcome for the patient. This case report emphasizes the relevance of employing different techniques in managing complicated dog bites.
动物咬伤是儿科发病率的一个重要来源,其中狗是主要原因。因此需要创新的解决方案来有效解决这一问题,并提高功能和美观效果。狗咬伤的发病率较高,由于唾液中含有大量细菌,因此存在固有的感染风险。治疗的基本方法是通过仔细清洗、清创和及时实施早期初级闭合术来预防感染。我们详细介绍了一名骨盆肢体被狗咬伤的儿科患者的治疗情况,该伤口极难处理。该病例在胶原基质床上进行了植皮,并用负压疗法进行了固定,治疗取得了成功。根据皮肤缺损的深度和大小,选择合适的技术重建皮肤缺损。因此,将这三种技术相结合,为患者带来了良好的功能和美学效果。本病例报告强调了在处理复杂的狗咬伤时采用不同技术的重要性。
{"title":"Skin graft on a collagen and elastin matrix fixed with negative pressure in a complicated pediatric dog bite: case report","authors":"Omar S. Fattel-Servin, Osvaldo I. Guevara-Valmaña, Sebastian Trigueiros-Guzmán, Valentina Prieto-Vargas, Ximena I. Ramirez-Morales, Armando Apellaniz-campo","doi":"10.18203/2349-2902.isj20240755","DOIUrl":"https://doi.org/10.18203/2349-2902.isj20240755","url":null,"abstract":"Animal bites represent a significant source of morbidity in the pediatric population, with dogs being the primary cause. Highlighting the need for innovative solutions to effectively tackle the issue and enhance both functional and aesthetic outcomes. Dog bites, marked by a heightened morbidity rate, present an inherent infection risk owing to the considerable bacterial load present in saliva. The fundamental approach to treatment revolves around preventing infection through meticulous washing, debridement, and the timely implementation of early primary closure. We detail the management of a pediatric patient with a dog bite on the pelvic limb, resulting in a challenging-to-manage wound. This case was successfully treated with a skin graft on a bed of collagen matrix, secured with negative pressure therapy. The choice of the appropriate technique for reconstructing skin defects depends on their depth and size. Consequently, combining these three techniques yielded a favorable functional and aesthetic outcome for the patient. This case report emphasizes the relevance of employing different techniques in managing complicated dog bites.","PeriodicalId":14372,"journal":{"name":"International Surgery Journal","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Surgery Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1