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Congenital hepatic hemangioma: a review 先天性肝血管瘤:综述
Pub Date : 2024-07-19 DOI: 10.18203/2349-2902.isj20241975
Gerardo M. Mendez, Miguel A. S. Juárez, Alejandro C. Jimenez, Axel T. O. Santamaría, Iván T. Torres
Congenital hepatic hemangioma (CHH) is a benign vascular malformation of the liver observed in newborns. Despite its rarity, it is crucial to understand its clinical presentation, diagnosis, and management due to potential complications. This extensive bibliographic review compiles key references to provide a detailed overview of the epidemiology, pathogenesis, clinical manifestations, diagnostic methods, and therapeutic options for CHH, aiming to offer a comprehensive insight into this condition.
先天性肝血管瘤(CHH)是新生儿肝脏的一种良性血管畸形。尽管这种疾病非常罕见,但由于其潜在的并发症,了解其临床表现、诊断和处理方法至关重要。这篇内容广泛的书目综述汇编了主要参考文献,详细概述了CHH的流行病学、发病机制、临床表现、诊断方法和治疗方案,旨在提供对这种疾病的全面见解。
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引用次数: 0
Pelvic congestion syndrome and its treatment: topic review 盆腔充血综合征及其治疗:专题回顾
Pub Date : 2024-07-19 DOI: 10.18203/2349-2902.isj20241974
Fernando G. R. Estrada, Miguel A. S. Juarez, Marlon E. L. Valenzuela
Pelvic congestion syndrome (PCS) is a pathology characterized by pain in the pelvic region that occurs chronically and is usually associated with the presence of varicose veins in the genital, vulvar or perineal region as a consequence of venous reflux of gonadal, gluteal or peri uterine veins, as well as compression syndromes in the left renal veins or iliac segments, which can lead to a spectrum of clinical symptoms ranging from dysuria, pain when standing, dyspareunia and intense dysmenorrhea, or equally psychological symptoms such as mood disorders or depression, which affect the quality of life of patients. Despite its high prevalence, this disease continues to be underdiagnosed and mistreated. The etiology varies involving factors in mechanics, hemodynamics, anatomical defects, anomalies of venous return, multiparity, including hormonal factors, obesity, or sedentary lifestyle, which favor blood stasis and consequent venous dilation. The diagnosis is made with an appropriate clinical examination, and confirmed with imaging studies, phlebography being the gold standard due to its diagnostic and therapeutic usefulness. There is currently a wide variety in the treatment of PCS, however endovascular management with sclerotherapy and embolization is the one that has shown the best results with clinical improvement and quality of life. This article seeks to review the literature on pelvic congestion syndrome with the aim of understanding a frequently overlooked disease and the diagnostic and therapeutic alternatives to treat these patients.
盆腔充血综合征(PCS)是一种以盆腔区域疼痛为特征的病理现象,这种疼痛长期发生,通常与生殖器、外阴或会阴区域的静脉曲张有关,是性腺、臀部或子宫周围静脉回流的结果、这些症状可导致一系列临床症状,包括排尿困难、站立时疼痛、排便困难和剧烈痛经,或同样的心理症状,如情绪障碍或抑郁,从而影响患者的生活质量。尽管这种疾病的发病率很高,但仍然没有得到充分诊断和治疗。病因多种多样,涉及力学、血液动力学、解剖学缺陷、静脉回流异常、多胎妊娠(包括激素因素)、肥胖或久坐不动的生活方式等因素,这些因素都有利于血液淤滞和随之而来的静脉扩张。诊断需要通过适当的临床检查,并通过影像学检查进行确诊,静脉造影因其诊断和治疗作用而成为金标准。目前,PCS 的治疗方法多种多样,但采用硬化剂注射和栓塞治疗的血管内治疗方法在改善临床症状和生活质量方面效果最佳。本文试图回顾有关盆腔充血综合征的文献,旨在了解这种经常被忽视的疾病,以及治疗这些患者的诊断和治疗方法。
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引用次数: 0
Retroperitoneal soft tissue sarcoma, a rare mimic and important differential of iliopsoas abscess 腹膜后软组织肉瘤,髂腰肌脓肿的罕见拟态和重要鉴别指标
Pub Date : 2024-07-09 DOI: 10.18203/2349-2902.isj20241956
Ryan J. Green, Sarath Vennam, Corey Kirkham, Conor Aylward, William Caufield, Lucy Andraloj, Miles Geldart, James Sellars
This case report highlights the diagnostic challenges posed by retroperitoneal soft tissue sarcoma (STS) presenting as an iliopsoas abscess, mimicking common symptoms and radiological findings. This patients’ symptoms recurred despite multiple percutaneous drains and revisions over a period of months. Further investigation revealed a partly solid, partly cystic mass consistent with sarcoma. Surgical excision confirmed the diagnosis, but recurrence necessitated palliation. This case emphasizes the importance of differential diagnoses of iliopsoas collection and the need for research into alternative imaging modalities to aid clinicians and radiologists in differentiating benign retroperitoneal collections from malignancy.
本病例报告强调了腹膜后软组织肉瘤(STS)以髂腰肌脓肿为表现形式、模仿常见症状和放射学检查结果所带来的诊断难题。尽管在数月内进行了多次经皮引流和翻修,但该患者的症状仍反复出现。进一步检查发现了一个部分实性、部分囊性的肿块,与肉瘤一致。手术切除证实了诊断,但由于复发而不得不采取姑息治疗。本病例强调了髂腰肌肿块鉴别诊断的重要性,以及研究其他成像方式的必要性,以帮助临床医生和放射科医生区分良性腹膜后肿块和恶性肿瘤。
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引用次数: 0
Giant pancreatic cyst with extension to spleen managed by laparoscopy 巨型胰腺囊肿扩展至脾脏,腹腔镜手术治疗
Pub Date : 2024-07-09 DOI: 10.18203/2349-2902.isj20241955
José Fernando Montiel Catañeda, Raúl Manuel Cota García, Antonio Valencia Vega, Darinel Osorio Gómez, Roman Esteban Hernández González, Brayant López García, Gabriela Díaz Salas, Miguel Ángel Adame Anzo, María José Cabrera Chávez, Jahat Uziel Lindoro Salgueiro
To review the etiology, clinical presentation, diagnostic evaluation, management, and prognosis of giant pancreatic cysts. Giant pancreatic cysts, defined as cysts exceeding 5 cm in diameter, include a diverse group of lesions such as pseudocysts, serous cystadenomas, mucinous cystic neoplasms (MCNs), and intraductal papillary mucinous neoplasms (IPMNs). Their clinical significance stems from potential complications and the necessity to differentiate benign from malignant cysts. A comprehensive review of the literature was conducted, focusing on the pathophysiology, symptomatology, diagnostic modalities, treatment options, and outcomes associated with giant pancreatic cysts. The etiology of giant pancreatic cysts varies from benign conditions like pseudocysts and serous cystadenomas to potentially malignant or malignant neoplasms such as MCNs and IPMNs. Clinical presentation ranges from asymptomatic cases to severe abdominal symptoms and complications. Diagnostic evaluation includes imaging modalities like ultrasound, CT, MRI/MRCP, and endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) for cytology and biochemical analysis. Management strategies depend on the type and characteristics of the cyst, with options including observation, endoscopic drainage, surgical resection, and percutaneous drainage. The prognosis varies, with benign cysts generally having a favorable outcome, while cysts with malignant potential require timely surgical intervention to improve survival rates. Giant pancreatic cysts pose a diagnostic and therapeutic challenge due to their varied etiologies and potential complications. Accurate diagnosis through advanced imaging and fluid analysis is crucial. Management should be tailored based on the cyst type, symptoms, and malignancy risk, involving a multidisciplinary approach to optimize patient outcomes. Further advancements in diagnostic and therapeutic techniques are anticipated to enhance the management of these complex lesions.
回顾巨型胰腺囊肿的病因、临床表现、诊断评估、治疗和预后。巨型胰腺囊肿是指直径超过 5 厘米的囊肿,包括假性囊肿、浆液性囊腺瘤、粘液性囊性瘤(MCN)和导管内乳头状粘液瘤(IPMN)等多种病变。它们的临床意义在于潜在的并发症以及区分良性和恶性囊肿的必要性。我们对相关文献进行了全面回顾,重点关注巨型胰腺囊肿的病理生理学、症状学、诊断方式、治疗方案和结果。巨型胰腺囊肿的病因多种多样,既有假性囊肿和浆液性囊腺瘤等良性病变,也有潜在的恶性或恶性肿瘤,如 MCN 和 IPMN。临床表现从无症状到严重腹部症状和并发症不等。诊断评估包括超声、CT、MRI/MRCP 和内窥镜超声(EUS)等成像模式,并进行细针穿刺(FNA)以进行细胞学和生化分析。治疗策略取决于囊肿的类型和特征,包括观察、内镜引流、手术切除和经皮引流。预后各不相同,良性囊肿一般预后良好,而有恶变可能的囊肿则需要及时进行手术治疗,以提高存活率。巨型胰腺囊肿的病因多种多样,并具有潜在的并发症,因此给诊断和治疗带来了挑战。通过先进的成像和液体分析进行准确诊断至关重要。应根据囊肿类型、症状和恶性肿瘤风险采取针对性的治疗措施,并采用多学科方法优化患者预后。预计诊断和治疗技术的进一步发展将加强对这些复杂病变的管理。
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引用次数: 0
Cerebrospinal fluid shunt catheter extrusion through the mouth in a child: a case report with brief literature review 儿童脑脊液分流导管从口中挤出:病例报告及简要文献综述
Pub Date : 2024-06-12 DOI: 10.18203/2349-2902.isj20241614
R. Ghritlaharey
Extrusion of the distal end of the cerebrospinal fluid (CSF) shunt catheter through the mouth is a rare complication of shunt surgery performed to treat hydrocephalus. A two-year-old girl had her first CSF shunt inserted when she was six months old to treat congenital hydrocephalus. The shunt became infected 2-months later and had to be removed. A few weeks later, a new CSF shunt was inserted on the left side. One year later, she presented with an extrusion of the distal end of the CSF shunt catheter through her mouth. However, she showed no symptoms or signs of peritonitis or meningitis. Her entire CSF shunt system on the left side required removal. A cranial magnetic resonance imaging (MRI) scan showed ventriculomegaly and a new CSF shunt catheter was implanted on the right side. She had an uneventful postoperative period and was doing well during the follow-up. Extrusion of the distal end of the CSF shunt catheter through the mouth is rare and more likely to occur in children, and clinicians need to be aware of such complications.
脑脊液(CSF)分流导管远端从口腔中挤出是治疗脑积水的分流手术中一种罕见的并发症。一名两岁女童在六个月大时首次植入了 CSF 分流器以治疗先天性脑积水。2 个月后,分流器受到感染,不得不将其移除。几周后,又在左侧植入了一个新的 CSF 分流器。一年后,她出现了脑脊液分流导管远端从口中挤出的情况。但是,她没有腹膜炎或脑膜炎的症状或体征。她左侧的整个脑脊液分流系统需要移除。头颅磁共振成像(MRI)扫描显示脑室肥大,于是在右侧植入了新的脑脊液分流导管。她的术后恢复顺利,随访期间情况良好。脑脊液分流导管远端从口中挤出的情况很少见,而且更容易发生在儿童身上,临床医生需要警惕此类并发症。
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引用次数: 0
Surgical site infections in elective and emergency general surgery cases in a tertiary public hospital of South India: a retrospective study 印度南部一家三级公立医院普外科择期手术和急诊手术中的手术部位感染:一项回顾性研究
Pub Date : 2024-06-12 DOI: 10.18203/2349-2902.isj20241613
Rahul G. Reji, C. Vijayakumar, G. Sreenath
Background: Surgical site infections (SSIs) are responsible for increased morbidity and mortality among post-operative patients worldwide. They also increase healthcare costs and prolong the duration of hospital stay. This study aims to determine the incidence of SSIs in elective and emergency general surgery and its association with various risk factors.Methods: A retrospective cohort study was carried out using the case sheets of 200 patients who underwent general surgery in a tertiary public hospital of South India. The patients were selected from two cohorts- emergency and elective (100 from each). The data retrieved from the hospital’s electronic medical records were analyzed using STATA version 14.0.Results: Of the 200 patients included in the study, 57% were men and the mean (range) age was 49.3 (18-88) years; 122 patients (61%) had contaminated wounds, 68 patients (34%) had a pre-existing comorbidity and the average duration of hospital stay was 6.98 days. The overall surgical site infection rate was 11%; 13% in emergency surgery and 9% in elective surgery. Staphylococcus aureus was isolated from 36% of the patients with surgical site infections.Conclusions: Emergency surgery reported a higher infection rate than elective surgery. Old age, pre-existing medical illnesses, wound contamination and prolonged hospital stay were also found to increase the risks for developing SSIs.
背景:手术部位感染(SSI)是导致全球术后患者发病率和死亡率上升的主要原因。它们还增加了医疗成本,延长了住院时间。本研究旨在确定普外科择期手术和急诊手术中 SSI 的发生率及其与各种风险因素的关系:一项回顾性队列研究使用了在南印度一家三级公立医院接受普外科手术的 200 名患者的病例表。这些患者分别来自急诊和择期手术(各 100 人)。研究人员使用 STATA 14.0 版对从医院电子病历中获取的数据进行了分析:在纳入研究的 200 名患者中,57% 为男性,平均年龄(范围)为 49.3(18-88)岁;122 名患者(61%)的伤口受到污染,68 名患者(34%)原有合并症,平均住院时间为 6.98 天。总的手术部位感染率为 11%;急诊手术为 13%,择期手术为 9%。36%的手术部位感染患者分离出了金黄色葡萄球菌:结论:急诊手术的感染率高于择期手术。结论:与择期手术相比,急诊手术的感染率更高,高龄、原有内科疾病、伤口污染和住院时间过长也会增加感染 SSI 的风险。
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引用次数: 0
Reduction of pancreatic leak rate after pancreaticoduodenectomy by changing anastomotic and drainage techniques: a long-term single center experience 通过改变吻合器和引流技术降低胰十二指肠切除术后的胰漏发生率:长期单中心经验
Pub Date : 2024-06-06 DOI: 10.18203/2349-2902.isj20241605
Mohamed Elsheikh, Amir Abdelhamid, Hossam R. Moussa
Background: Pancreaticoduodenectomy is the best curative option for malignant pancreatic head neoplasms with a high perioperative morbidity rate. Pancreatic leak is the most feared complication. This study was done to describe our early and late experience outcomes of PD after implementing technical modifications to decrease the postoperative incidence of pancreatic leak.Methods: The data of 53 patients were collected and divided into two groups: the early experience group (27 cases) and the late experience group (26 cases). The main two modifications performed in late group were Heidelberg technique for pancreatojejunostomy anastomosis (all cases) and irrigation of the pancreatic anastomosis (selected cases).Results: All preoperative demographic, clinical, laboratory, and intraoperative findings showed insignificant differences between the two groups (p≥0.05). Nonetheless, cases in the late group had shorter operative time, less intraoperative blood loss, and less need for blood transfusion (p<0.05(. Postoperatively, the incidence of pancreatic leak decreased with technical modifications (11.54% vs. 37.04% in the early group). The late group showed earlier time to oral intake and shorter hospitalization periods. In-hospital mortality occurred in 14.81% of early cases secondary to pancreatic leak and subsequent secondary haemorrhage and multiorgan failure. Obesity (p<0.001), soft pancreas (p<0.001), and small pancreatic duct diameter (p=0.007) were significant predictors of pancreatic leak.Conclusions: Surgical expertise and technical modifications play a crucial role in improving PD outcomes with less incidence of complications, earlier oral intake, and shorter hospitalization period.
背景:胰十二指肠切除术是治愈恶性胰头肿瘤的最佳选择,但围手术期发病率较高。胰漏是最可怕的并发症。本研究旨在描述我们为降低术后胰漏发生率而进行技术改造后,胰头癌早期和晚期的治疗效果:收集了 53 例患者的数据,并将其分为两组:早期经验组(27 例)和晚期经验组(26 例)。晚期经验组主要进行了两项改良:胰空肠吻合术的海德堡技术(所有病例)和胰腺吻合术的灌洗(部分病例):所有术前人口统计学、临床、实验室和术中检查结果显示,两组间差异不显著(P≥0.05)。然而,晚期组病例的手术时间更短、术中失血更少、输血需求更少(P<0.05)。术后,胰漏发生率随着技术改造而降低(早期组为 11.54% 对 37.04%)。晚期组口服时间更早,住院时间更短。14.81%的早期病例因胰腺漏、继发出血和多器官功能衰竭而出现院内死亡。肥胖(p<0.001)、软胰腺(p<0.001)和胰管直径小(p=0.007)是胰漏的重要预测因素:结论:外科专业知识和技术改造在改善胰漏预后方面起着至关重要的作用,并发症发生率低,口服时间早,住院时间短。
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引用次数: 0
Ultrasound guided aspiration versus incision and drainage in the management of breast abscess 超声引导下抽吸与切开引流术治疗乳腺脓肿的比较
Pub Date : 2024-05-18 DOI: 10.18203/2349-2902.isj20241308
Prashanth C., Neetha V., Likhith Kumar R., Manohar T. M.
Background: The aim of this study is to compare the results of ultrasound guided aspiration and incision and drainage in the management of breast abscess.Methods: This is a comparative study of between ultrasound guided aspiration and incision and drainage, consist of 50 patients with breast abscess who underwent both the treatment alternatively in our institution Sri. Siddhartha Institute of Medical Sciences and Research Begur during 2021 to 2023. 7th and 14th day following aspiration, patients should be assessed both clinically and by USG breast. Results were tabulated and analyzed.Results: 4 patients developed complications following Incision and drainage. 3 milk fistula and wound gaping, 1 recurrence and 3 patients developed complications following USG guided aspiration All 3 cases were recurrence.Conclusions: USG guided aspiration is simple, painless, day care procedure and effective alternative method of treatment to incision and drainage in properly selected patient and with timely support by sonologist with early postoperative recovery and good patient satisfaction.
背景:本研究旨在比较超声引导下抽吸和切开引流术治疗乳腺脓肿的效果:本研究旨在比较超声引导下抽吸术和切开引流术治疗乳腺脓肿的效果:这是一项关于超声引导下抽吸术与切开引流术的比较研究,研究对象是在 2021 年期间在本院 Sri.Siddhartha Institute of Medical Sciences and Research Begur的50名乳腺脓肿患者。抽吸后第 7 天和第 14 天,患者应接受临床和乳腺 USG 评估。对结果进行列表和分析:结果:4 名患者在切开引流术后出现并发症。结果:4 例患者在切开引流术后出现并发症,3 例出现乳瘘和伤口裂开,1 例复发,3 例患者在 USG 引导下抽吸术后出现并发症,所有 3 例均为复发:结论:USG 引导下抽吸术是一种简单、无痛、日间护理的手术,对于经过适当选择的患者,在超声科医生的及时支持下,可有效替代切开引流术,术后恢复快,患者满意度高。
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引用次数: 0
A heterotopic pregnancy at 12 weeks’ pregnancy 怀孕 12 周时出现异位妊娠
Pub Date : 2024-05-16 DOI: 10.18203/2349-2902.isj20241306
Wiwin Suhandri, Diki Riandi
Heterotopic pregnancy (HP) represents a rare and complex condition where simultaneous pregnancies occur at different implantation sites, with only one located within the uterine cavity. Typically diagnosed in the first trimester, HP presents diagnostic challenges due to its rarity and varying clinical presentations. Here, we present a unique case of HP diagnosed at Bengkalis Hospital involving a 42-year-old multipara at 12 weeks of gestation. The patient's presentation included regular uterine contractions and upper abdominal pain, with a positive Plano test upon admission. Despite experiencing vaginal bleeding two days prior and an initial refusal of care, further examination revealed a 2.13 cm gestational sac in the intrauterine cavity, consistent with the gestational age. Additionally, free intra-abdominal fluid was observed in the Douglas cavity. Haematological examination indicated a low haemoglobin level of 7.2 g/dl and elevated leukocytes at 16,000. An emergency laparotomy revealed a ruptured right ovarian tube containing a gestational sac, which was managed with hemostasis and a subsequent salpingectomy. The left ovarian tube underwent a tubectomy as a preventive measure. The patient received multiple blood transfusions, leading to an improvement in haemoglobin levels to 10.2 g/dl postoperatively. Following a two-day hospitalisation, the patient was discharged in good general condition. HP cases often necessitate laparotomies for tubal pregnancies, and ultrasound plays a crucial role in diagnosis, especially given its prevalence of 1 in 7000 due to assisted reproduction. Treatment typically involves laparoscopic or laparotomic intervention, highlighting the multidisciplinary approach required for managing this rare condition.
异位妊娠(HP)是一种罕见而复杂的病症,即同时妊娠发生在不同的着床部位,只有一个着床部位位于子宫腔内。异位妊娠通常在妊娠头三个月被诊断出来,由于其罕见性和不同的临床表现,给诊断带来了挑战。在此,我们介绍一例在 Bengkalis 医院确诊的独特 HP 病例,患者 42 岁,多胎,妊娠 12 周。患者表现为规律性子宫收缩和上腹部疼痛,入院时普拉诺试验呈阳性。尽管患者两天前曾出现阴道出血,而且最初拒绝接受治疗,但进一步检查发现宫腔内有一个 2.13 厘米的妊娠囊,与孕龄相符。此外,在道格拉斯腔内还发现了游离的腹腔积液。血液检查显示血红蛋白水平低至 7.2 g/dl,白细胞升高至 16 000。紧急开腹手术显示右侧卵巢管破裂,内含一个妊娠囊,经止血处理后进行了输卵管切除术。作为预防措施,对左侧卵巢管进行了切除。患者接受了多次输血,术后血红蛋白水平提高到 10.2 g/dl。经过两天的住院治疗,患者出院时全身状况良好。输卵管妊娠 HP 病例通常需要开腹手术,超声波在诊断中起着至关重要的作用,特别是考虑到由于辅助生殖,其发病率高达 1/7000。治疗方法通常包括腹腔镜或腹腔镜干预,这突出说明了治疗这种罕见疾病所需的多学科方法。
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引用次数: 0
Towards zero bleeding after laparoscopic sleeve gastrectomy: investigating the impact of prophylactic tranexamic acid 腹腔镜袖带胃切除术后实现零出血:研究预防性氨甲环酸的影响
Pub Date : 2024-05-16 DOI: 10.18203/2349-2902.isj20241307
Owaid M. Almalki
Background: Laparoscopic sleeve gastrectomy (LSG) is a prevalent bariatric procedure known for its efficacy in weight loss and amelioration of obesity-related comorbidities. However, postoperative bleeding from the staple line remains a significant complication, necessitating strategies for effective hemostasis. Tranexamic acid (TXA) has shown promise in reducing bleeding complications in various surgical contexts, yet its role in LSG remains underexplored due to concerns about thromboembolic risks.Methods: This retrospective comparative analysis examines the impact of prophylactic TXA administration on perioperative bleeding in LSG patients. Two cohorts of 100 patients each, undergoing LSG before and after TXA implementation, were analyzed. Demographic, clinical, and outcome data were collected and statistically analyzed.Results: In our study, 100 patients received TXA with a mean age of 36.8±12.18 years, while another 100 formed the non-TXA group with a mean age of 37.2±11.81 years. Pre-surgery, clinical characteristics and hemodynamic parameters did not significantly differ between groups. However, post-surgery, TXA patients showed significantly elevated hemoglobin levels (p=0.019), increased hematocrit (p<0.001), higher prothrombin activity (p=0.002), decreased INR values (p=0.012), and higher fibrinogen levels (p=0.014) compared to non-TXA patients. Three non-TXA patients experienced post-operative bleeding requiring ICU admission and transfusions. The mean length of stay was 2.1±0.5 days for TXA patients and 2.2±0.03 days for non-TXA patients. No venous thromboembolism (VTE) or deaths occurred in either group.Conclusions: The integration of prophylactic TXA into perioperative protocols for LSG holds promise in optimizing hemostasis and enhancing patient outcomes. TXA serves as a valuable adjunctive strategy towards minimizing bleeding events and bolstering safety in LSG procedures.
背景:腹腔镜袖带胃切除术(LSG)是一种流行的减肥手术,因其在减轻体重和改善肥胖相关并发症方面的疗效而闻名。然而,术后缝合线出血仍是一个重要的并发症,需要采取有效的止血策略。氨甲环酸(TXA)在各种手术中都显示出减少出血并发症的前景,但由于担心血栓栓塞风险,其在全胃肠镜中的作用仍未得到充分探索:这项回顾性对比分析研究了预防性使用 TXA 对 LSG 患者围手术期出血的影响。分析了实施 TXA 之前和之后接受 LSG 的两组患者,每组 100 人。我们收集了人口统计学、临床和结果数据,并进行了统计分析:在我们的研究中,100 名患者接受了 TXA 治疗,平均年龄为(36.8±12.18)岁;另外 100 名患者组成了非 TXA 组,平均年龄为(37.2±11.81)岁。两组患者手术前的临床特征和血液动力学参数无明显差异。然而,与非 TXA 患者相比,手术后 TXA 患者的血红蛋白水平明显升高(p=0.019),血细胞比容升高(p<0.001),凝血酶原活动度升高(p=0.002),INR 值降低(p=0.012),纤维蛋白原水平升高(p=0.014)。三名非 TXA 患者术后出血,需要入住重症监护室和输血。TXA患者的平均住院时间为2.1±0.5天,非TXA患者的平均住院时间为2.2±0.03天。两组患者均未发生静脉血栓栓塞(VTE)或死亡:结论:将预防性 TXA 纳入 LSG 围手术期方案有望优化止血效果并改善患者预后。TXA是一种有价值的辅助策略,可最大限度地减少出血事件,提高LSG手术的安全性。
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引用次数: 0
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International Surgery Journal
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