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Assessing the Effectiveness of Padlet Instructional Tool in the Teaching and Learning of some Ecological Concepts 评估小板教学工具在一些生态概念教与学中的有效性
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2554
M. Baidoo, Y. Ameyaw, J. N. Annan
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引用次数: 0
Rusho-Ramanujan Fourier Series Rusho-Ramanujan傅里叶级数
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2599
Maher Ali Rusho
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引用次数: 0
Progress in the Treatment of Neonatal Respiratory Distress Syndrome 新生儿呼吸窘迫综合征的治疗进展
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2579
H. Hui, Jun Yu Li
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引用次数: 0
An Ecological Strategy to Reduce and Optimize Nitrogenous Fertilizer in the Growth of Solaneum lycopersicum 番茄茄生长过程中氮肥减量与优化的生态策略
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2620
Alexis Javier Nava-Vazquez, Juan Luis Ignacion de la Cruz, Juan Manuel Sanchez-Yañez
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引用次数: 0
Diagnosis and Treatment of Patients with Trigeminal Neuralgia: A Review 三叉神经痛的诊断与治疗综述
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2608
Valdecir Carlos Tadei
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引用次数: 0
De Novo Designed Peptide to Prevent SARS-CoV-2 Interaction with ACE2 Receptor on Host Cells De Novo设计的肽阻止SARS-CoV-2与宿主细胞上ACE2受体的相互作用
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2558
I. Cosic, U. Kuhar, U. Krapež, B. Slavec, D. Cosic, I. Loncarevic
: COVID-19 pandemic, which has made havoc in the World, is caused by single stranded RNA virus SARS-C0V-2. This virus attacks cells by interacting with Angiotensin-Converting Enzyme 2 (ACE2) receptor on the surface of host cells. Using the Resonant Recognition Model (RRM), we have designed six de novo peptides which are proposed to prevent this interaction. Peptide preselection has been by standard Inhibitor Screening Assay Kits and one of the designed peptides (CovA) has been proposed to be a good candidate for testing on cell lines. Using Vero E6 cell line, peptide CovA has shown ability to significantly prevent interaction between SARS-CoV-2 virus and ACE2 receptor. Thus, the designed peptide CovA could provide the basis for development of new COVID-19 drugs. In addition, these results are supporting the RRM model ability to design peptides with desired biological function.
:肆虐全球的新冠肺炎大流行是由单链RNA病毒SARS-C0V-2引起的。这种病毒通过与宿主细胞表面的血管紧张素转换酶2 (ACE2)受体相互作用来攻击细胞。利用共振识别模型(RRM),我们设计了六个新的肽来防止这种相互作用。通过标准抑制剂筛选测定试剂盒对肽进行了预选,并提出了一种设计的肽(CovA)作为细胞系测试的良好候选肽。利用Vero E6细胞系,肽CovA显示出显著阻止SARS-CoV-2病毒与ACE2受体相互作用的能力。因此,设计的肽CovA可为新型COVID-19药物的开发提供基础。此外,这些结果支持RRM模型设计具有所需生物学功能的肽的能力。
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引用次数: 2
Chemical and Radiological Risk Assessment of Uranium in Surface and Groundwater in Ogoni Land, Rivers State, Nigeria 尼日利亚河流州奥戈尼地地表水和地下水中铀的化学和放射性风险评估
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2581
Thompson Chinedum Irunkwor, Alexander Amechi Odagwe, B. Atalor
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引用次数: 1
Therapeutic Effects of Kv7 Channel Activator Retigabine against Seizures and Neurodegeneration in Kainic Acid-Induced Seizure Model Kv7通道激活剂雷加滨对凯尼克酸致癫痫模型癫痫发作和神经变性的治疗作用
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2598
Xiaobo Zhuang
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引用次数: 0
Influence of Mechanical Shelling on the Microbiological and Physico-Chemical Quality of Souna Millet (Pennisetum glaucum) and its Derivatived 机械脱壳对谷子及其衍生物微生物和理化品质的影响
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2573
Adjaratou Basse, Donatien Kaboré, Mamadou Salif Sow, Seynabou Momar Fall, E. Dieme, F. Diallo, Magatte Fall, Mamoudou Hama Dicko
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引用次数: 0
Modification of Periodic Acid Schiff and Haematoxylin Van Geison Solutions with Ethanol and Ethyl Acetate Wood Extract of Erythroxylum 用乙醇和乙酸乙酯对周期性酸性席夫和紫杉醇溶液进行改性
Pub Date : 2022-01-01 DOI: 10.18483/ijsci.2567
N. Okorie, Jessica Chioma OJUKWU, Samuel A. FASOGBON, Uchenna Oyibe OKEKPA, Adebukola Adisa Ekoh-Jolly, Cyril A. EGBO, Sumbola A. ADEYINKA, Samuel Ehiremen, Odinaka Kingsley OBETA, Ibukun Akinsola OMISAKIN, Adekunle Oluwatosin ADELUWOYE
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引用次数: 0
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International journal of sciences
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