Pub Date : 2023-12-31DOI: 10.23937/2469-567x/1510090
Onyeka Odiase Edgar, M. Olley, Ugbomoiko Daniel Ohilebo, Erameh Theophilus Ogie, Gambo Ezekiel Dauda, Kanwulia Ofili Sandra, Ibrahim Muhammad Adamu, Ntasin Paul Yiran
{"title":"Prevalence of Mycobacterium tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State","authors":"Onyeka Odiase Edgar, M. Olley, Ugbomoiko Daniel Ohilebo, Erameh Theophilus Ogie, Gambo Ezekiel Dauda, Kanwulia Ofili Sandra, Ibrahim Muhammad Adamu, Ntasin Paul Yiran","doi":"10.23937/2469-567x/1510090","DOIUrl":"https://doi.org/10.23937/2469-567x/1510090","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"74 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-31DOI: 10.23937/2469-567x/1510091
Iqbal Myra Sarfraz
{"title":"siRNA-Therapy for Hepatitis B Virus (HBV): A Novel Choice for HBV Treatment","authors":"Iqbal Myra Sarfraz","doi":"10.23937/2469-567x/1510091","DOIUrl":"https://doi.org/10.23937/2469-567x/1510091","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"11 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139135565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.23937/2469-567x/1510084
AlAgha Rawan
{"title":"Thrombotic Microangiopathies as Initial Presentation of HIV: Two Case Reports and Literature Review","authors":"AlAgha Rawan","doi":"10.23937/2469-567x/1510084","DOIUrl":"https://doi.org/10.23937/2469-567x/1510084","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88046726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Onu, Emmanuel Onu, C. Ejikeugwu, C. Azi, J. Ugwu, O. Ogbu
{"title":"Seroprevalence and Molecular Investigation of Human Papillomavirus (HPV) Type-16 in HIV Positive Women in Abakaliki, Nigeria","authors":"E. Onu, Emmanuel Onu, C. Ejikeugwu, C. Azi, J. Ugwu, O. Ogbu","doi":"10.3923/ijv.2023.1.5","DOIUrl":"https://doi.org/10.3923/ijv.2023.1.5","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79507039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.23937/2469-567x/1510087
{"title":"Aids and Non-Hodgkin Lymphoma: Report of a Case","authors":"","doi":"10.23937/2469-567x/1510087","DOIUrl":"https://doi.org/10.23937/2469-567x/1510087","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87093948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.23937/2469-567x/1510089
Andigema Angyiba Serge, Cyrielle NGNOTOUOM NGNOKAM Tania, Landry KOUDOM Patrice, Vladimir ABENA Jerry
{"title":"AI in the Management of HIV: Case Study Cameroon","authors":"Andigema Angyiba Serge, Cyrielle NGNOTOUOM NGNOKAM Tania, Landry KOUDOM Patrice, Vladimir ABENA Jerry","doi":"10.23937/2469-567x/1510089","DOIUrl":"https://doi.org/10.23937/2469-567x/1510089","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78325522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.23937/2469-567x/1510088
Aggarwal H.K., J. Deepak, H. P, Dr Shaveta, K. Sandeep, K. Ashwani
Background: With the advent of HAART, natural history of HIV/AIDS has changed radically and PLHIV who are treated before significant immunosuppression can expect to have a longer life expectancy. Previous studies have suggested a rising rate of non-AIDS related events in HIV infected individuals of which cardiovascular diseases constitute significant morbidity and mortality. Identification of factors augmenting the cardiovascular risk is important in the management of HIV. Methods: The present study was a cross-sectional, observational study carried out in a tertiary care centre from January 2021 to July 2022. 200 HIV positive individuals on HAART for atleast 2 years were included who underwent ECG, chest radiograph, 2D Echocardiography and CD4+ T cell count along with other routine investigations. Presence of cardiovascular involvement was determined on the basis of echocardiographic abnormalities and these findings were associated with demographic, haematological and biochemical profile of the patients. The echocardiographic abnormalities were correlated with CD4+ T cell count and clinical stage of the disease. Results: 38.50% of the population had abnormal ECG findings of which sinus tachycardia was the most common (30.00%). The prevalence of echocardiographic abnormalities was 41.00%. The most common echocardiographic abnormality was diastolic dysfunction (32.00%) followed by valvular insufficiency (21.00%) and reduced LVEF (15.00%). The mean of CD4+ T cell count in those with abnormal echocardiographic findings was 194.43 ± 161.4 cells/mm3 which was significantly lower than those with normal echocardiographic findings (555.02 ± 393.36 cells/ mm3). With decrease in the CD4+ T cell count and with increase in WHO stage, cardiac abnormalities increased significantly. Higher grades of diastolic dysfunction were seen with CD4+ T cell count < 350/mm3 and WHO stages 3 and 4. Conclusion: In the present study, there was a high prevalence of cardiovascular abnormalities among PLHIV. Lower CD4+ T cell count was an independent risk factor for cardiovascular abnormalities and hence predicts the occurrence of cardiovascular disorders among PLHIV.
{"title":"Cardiovascular Involvement in People Living with Human Immunodeficiency Virus on Highly Active Antiretroviral Therapy","authors":"Aggarwal H.K., J. Deepak, H. P, Dr Shaveta, K. Sandeep, K. Ashwani","doi":"10.23937/2469-567x/1510088","DOIUrl":"https://doi.org/10.23937/2469-567x/1510088","url":null,"abstract":"Background: With the advent of HAART, natural history of HIV/AIDS has changed radically and PLHIV who are treated before significant immunosuppression can expect to have a longer life expectancy. Previous studies have suggested a rising rate of non-AIDS related events in HIV infected individuals of which cardiovascular diseases constitute significant morbidity and mortality. Identification of factors augmenting the cardiovascular risk is important in the management of HIV. Methods: The present study was a cross-sectional, observational study carried out in a tertiary care centre from January 2021 to July 2022. 200 HIV positive individuals on HAART for atleast 2 years were included who underwent ECG, chest radiograph, 2D Echocardiography and CD4+ T cell count along with other routine investigations. Presence of cardiovascular involvement was determined on the basis of echocardiographic abnormalities and these findings were associated with demographic, haematological and biochemical profile of the patients. The echocardiographic abnormalities were correlated with CD4+ T cell count and clinical stage of the disease. Results: 38.50% of the population had abnormal ECG findings of which sinus tachycardia was the most common (30.00%). The prevalence of echocardiographic abnormalities was 41.00%. The most common echocardiographic abnormality was diastolic dysfunction (32.00%) followed by valvular insufficiency (21.00%) and reduced LVEF (15.00%). The mean of CD4+ T cell count in those with abnormal echocardiographic findings was 194.43 ± 161.4 cells/mm3 which was significantly lower than those with normal echocardiographic findings (555.02 ± 393.36 cells/ mm3). With decrease in the CD4+ T cell count and with increase in WHO stage, cardiac abnormalities increased significantly. Higher grades of diastolic dysfunction were seen with CD4+ T cell count < 350/mm3 and WHO stages 3 and 4. Conclusion: In the present study, there was a high prevalence of cardiovascular abnormalities among PLHIV. Lower CD4+ T cell count was an independent risk factor for cardiovascular abnormalities and hence predicts the occurrence of cardiovascular disorders among PLHIV.","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"263 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85899127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.23937/2469-567x/1510085
Mosa Behre Dari, Wabe Yasin Awol, Mohammed Neja Awol
{"title":"Current Update of Severe Acute Respiratory Syndrome Coronavirus 2","authors":"Mosa Behre Dari, Wabe Yasin Awol, Mohammed Neja Awol","doi":"10.23937/2469-567x/1510085","DOIUrl":"https://doi.org/10.23937/2469-567x/1510085","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74243680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.23937/2469-567x/1510083
Katbi Moses, Bello Maryam, A. Oluwatosin, Adedoyin Adefisayo, Ukaere Amalachukwu, Gold Rachel, K. Kent, F. Iyiola, Meri Helina, Swomen Homsuk, A. Adegboye
{"title":"The Intersection of Two Pandemics: Elucidating the Impact of COVID-19 Restrictions on HIV Services among Key Populations in Northeast Nigeria","authors":"Katbi Moses, Bello Maryam, A. Oluwatosin, Adedoyin Adefisayo, Ukaere Amalachukwu, Gold Rachel, K. Kent, F. Iyiola, Meri Helina, Swomen Homsuk, A. Adegboye","doi":"10.23937/2469-567x/1510083","DOIUrl":"https://doi.org/10.23937/2469-567x/1510083","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90577686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Okoth, C. Onzere, C. Gallardo, M. Arias, J. Kasiti Lic, J. Macharia, R. Bishop
{"title":"First Detection of African Swine Fever Virus Genotype IX at the Kenya Coast","authors":"E. Okoth, C. Onzere, C. Gallardo, M. Arias, J. Kasiti Lic, J. Macharia, R. Bishop","doi":"10.3923/ijv.2022.1.6","DOIUrl":"https://doi.org/10.3923/ijv.2022.1.6","url":null,"abstract":"","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85353238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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