Pub Date : 2014-11-01DOI: 10.35215/JCJ.2014.1..002
Taejong Chung
{"title":"A Study on the Problematics of the Korean Dualistic System of Judicial Review of Administrative Orders and Rules and a Proposed Amendment to the Article 107 Section 2 of the Korean Constitution","authors":"Taejong Chung","doi":"10.35215/JCJ.2014.1..002","DOIUrl":"https://doi.org/10.35215/JCJ.2014.1..002","url":null,"abstract":"","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"10 1","pages":"39-85"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82146966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-11-01DOI: 10.35215/JCJ.2014.1..007
SooWoong Han
{"title":"Die verfassungsrechtliche Grenze der das kommunale Selbstverwaltungsrecht einschränkenden gesetzlichen Regelung - insbesondere in bezug auf die Probleme der Kernbereichsgarantie in der Rechtsprechung des Verfassungsgerichts -","authors":"SooWoong Han","doi":"10.35215/JCJ.2014.1..007","DOIUrl":"https://doi.org/10.35215/JCJ.2014.1..007","url":null,"abstract":"","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"26 1","pages":"235-280"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74400625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-04-01DOI: 10.1253/circj.cj-66-0080
H. Shimokawa
{"title":"MESSAGE FROM THE EDITOR-IN-CHIEF : Rapid Publication and Announcement of the 2016 JCS Meeting Activities","authors":"H. Shimokawa","doi":"10.1253/circj.cj-66-0080","DOIUrl":"https://doi.org/10.1253/circj.cj-66-0080","url":null,"abstract":"","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"144 1","pages":"779-781"},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74585861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-02-01DOI: 10.1253/CIRCJ.CJ-66-0078
H. Shimokawa
{"title":"MESSAGE FROM THE EDITOR-IN-CHIEF : Editorial Statistics and Best Reviewers Award for 2013","authors":"H. Shimokawa","doi":"10.1253/CIRCJ.CJ-66-0078","DOIUrl":"https://doi.org/10.1253/CIRCJ.CJ-66-0078","url":null,"abstract":"","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"10 1","pages":"267-270"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90364888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-10-01DOI: 10.1016/J.CARDFAIL.2013.08.239
K. Hao, J. Takahashi, K. Ito, S. Miyata, Y. Sakata, T. Nihei, R. Tsuburaya, T. Shiroto, Yoshitaka Ito, Y. Matsumoto, M. Nakayama, S. Yasuda, H. Shimokawa
{"title":"Emergency Care of Acute Myocardial Infarction and the Great East Japan Earthquake Disaster:– Report From the Miyagi AMI Registry Study –","authors":"K. Hao, J. Takahashi, K. Ito, S. Miyata, Y. Sakata, T. Nihei, R. Tsuburaya, T. Shiroto, Yoshitaka Ito, Y. Matsumoto, M. Nakayama, S. Yasuda, H. Shimokawa","doi":"10.1016/J.CARDFAIL.2013.08.239","DOIUrl":"https://doi.org/10.1016/J.CARDFAIL.2013.08.239","url":null,"abstract":"","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"23 1","pages":"634-643"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91157749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-11-20DOI: 10.1253/circj.cj-10-74-0202
K. Nishiyama, T. Tsutamoto, Masayuki Yamaji, Chiho Kawahara, Takashi Yamamoto, M. Fujii, M. Horie
he β-blockers improve cardiac function and prolong survival in patients with systolic chronic heart failure (CHF).1–4 In the Multicenter Oral Carvedilol Heart Failure Assessment (MOCHA) trial, carvedilol (6.25– 25 mg/day) was associated with dose-related improvements in left ventricular (LV) function and survival in heart failure (HF) patients in a population that was 77% Caucasian.5 However, the response to carvedilol may vary among different ethnic groups6–9 and indeed, the dose of carvedilol for treatment in Japanese is 10–20 mg/day, which is less than half of the dose used in Western patients.10,11 In the Multicenter Carvedilol Heart Failure Dose Assessment (MUCHA) trial, low-dose carvedilol (5 mg/day group or 20 mg/day group) improved the LV ejection fraction (LVEF) and reduced cardiovascular hospitalization in Japanese patients with CHF.12 In addition, carvedilol therapy achieved a dose-related improvement in CHF and LVEF; cardiovascular hospitalization was markedly reduced. However, the relationship between the dose-dependent improvement of carvedilol and prognosis in Japanese patients with CHF remains unknown. Cardiac sympathetic nerve activity (CSA) plays an important role in the pathophysiology of CHF.13–17 We previously reported that CSA plays an important role in the pathophysiology of CHF, independent of hemodynamic overload, and that the transcardiac gradient of norepinephrine (NE) is a more reliable biomarker of CSA than the peripheral venous NE level.18,19 Moreover, carvedilol treatment has been reported as associated with a significant reduction in the transcardiac gradient of NE, without any changes in the plasma arterial NE, in patients with CHF.20 There has not previously been a study correlating the transcardiac gradient of NE, brain natriuretic peptide (BNP) and N-terminal BNP (NT-proBNP) with the dose of carvedilol. In the present study, we investigated the relationship of these parameters with the prognosis of CHF in the same population.
{"title":"Dose-Dependent Prognostic Effect of Carvedilol in Patients With Chronic Heart Failure::Special Reference to Ranscardiac Gradient of Norepinephrine","authors":"K. Nishiyama, T. Tsutamoto, Masayuki Yamaji, Chiho Kawahara, Takashi Yamamoto, M. Fujii, M. Horie","doi":"10.1253/circj.cj-10-74-0202","DOIUrl":"https://doi.org/10.1253/circj.cj-10-74-0202","url":null,"abstract":"he β-blockers improve cardiac function and prolong survival in patients with systolic chronic heart failure (CHF).1–4 In the Multicenter Oral Carvedilol Heart Failure Assessment (MOCHA) trial, carvedilol (6.25– 25 mg/day) was associated with dose-related improvements in left ventricular (LV) function and survival in heart failure (HF) patients in a population that was 77% Caucasian.5 However, the response to carvedilol may vary among different ethnic groups6–9 and indeed, the dose of carvedilol for treatment in Japanese is 10–20 mg/day, which is less than half of the dose used in Western patients.10,11 In the Multicenter Carvedilol Heart Failure Dose Assessment (MUCHA) trial, low-dose carvedilol (5 mg/day group or 20 mg/day group) improved the LV ejection fraction (LVEF) and reduced cardiovascular hospitalization in Japanese patients with CHF.12 In addition, carvedilol therapy achieved a dose-related improvement in CHF and LVEF; cardiovascular hospitalization was markedly reduced. However, the relationship between the dose-dependent improvement of carvedilol and prognosis in Japanese patients with CHF remains unknown. Cardiac sympathetic nerve activity (CSA) plays an important role in the pathophysiology of CHF.13–17 We previously reported that CSA plays an important role in the pathophysiology of CHF, independent of hemodynamic overload, and that the transcardiac gradient of norepinephrine (NE) is a more reliable biomarker of CSA than the peripheral venous NE level.18,19 Moreover, carvedilol treatment has been reported as associated with a significant reduction in the transcardiac gradient of NE, without any changes in the plasma arterial NE, in patients with CHF.20 There has not previously been a study correlating the transcardiac gradient of NE, brain natriuretic peptide (BNP) and N-terminal BNP (NT-proBNP) with the dose of carvedilol. In the present study, we investigated the relationship of these parameters with the prognosis of CHF in the same population.","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"18 1","pages":"2270-2275"},"PeriodicalIF":0.0,"publicationDate":"2009-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76884349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-11-20DOI: 10.1253/CIRCJ.CJ-08-0933
Y. Mizuguchi, T. Oki
We appreciate the interesting comments by Dr Ntaios and colleagues who raised several important points that were not emphasized in our article.1 We demonstrated that 1-year pitavastatin treatment improves left ventricular function and carotid arterial stiffness, but there was an insufficient effect of pitavastatin on carotid intima–media thickness (IMT) in our study. 1 As they pointed out, however, several other studies have indicated that statin therapy decreases carotid IMT. 2–9 In our study, the maximum and mean IMTs after pitavastatin therapy tended to decrease, but there were no significant differences. In addition, we previously reported that left ventricular function, particularly diastolic function, is strongly related to carotid or aortic arterial stiffness rather than carotid IMT in subclinical patients with cardiovascular risk factors. 10,11
{"title":"Reply to Letter Regarding Article, \"Impact of Statin Therapy on Left Ventricular Function and Carotid Arterial Stiffness in Patients With Hypercholesterolemia\"(Letter to the Editor)","authors":"Y. Mizuguchi, T. Oki","doi":"10.1253/CIRCJ.CJ-08-0933","DOIUrl":"https://doi.org/10.1253/CIRCJ.CJ-08-0933","url":null,"abstract":"We appreciate the interesting comments by Dr Ntaios and colleagues who raised several important points that were not emphasized in our article.1 We demonstrated that 1-year pitavastatin treatment improves left ventricular function and carotid arterial stiffness, but there was an insufficient effect of pitavastatin on carotid intima–media thickness (IMT) in our study. 1 As they pointed out, however, several other studies have indicated that statin therapy decreases carotid IMT. 2–9 In our study, the maximum and mean IMTs after pitavastatin therapy tended to decrease, but there were no significant differences. In addition, we previously reported that left ventricular function, particularly diastolic function, is strongly related to carotid or aortic arterial stiffness rather than carotid IMT in subclinical patients with cardiovascular risk factors. 10,11","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"13 1","pages":"2102"},"PeriodicalIF":0.0,"publicationDate":"2008-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75855312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-09-20DOI: 10.1253/circj.cj-08-0759
G. Nakazawa, K. Tanabe, K. Hara
BACKGROUND Metallic allergy is associated with restenosis following bare metal stent implantation, but the impact of metallic allergy on the outcome after implantation of drug-eluting stents (DES) has not been investigated. METHODS AND RESULTS The present study group consisted of 88 consecutive patients (109 lesions) who underwent percutaneous coronary intervention with sirolimus-eluting stents (SES). Follow-up angiography was obtained at 8 months in all patients. At that time, the patients underwent epicutaneous patch tests for nickel, chromate, molybdenum, manganese, and titanium, which were evaluated after 48 h of contact. The patch test was positive in 14 patients (16%) (5 for manganese, 3 for nickel, 1 for chromate, 1 for Nickel and manganese, and 4 for manganese and chromate). The binary restenosis rate in the patients with a positive patch test was similar to those with negative patch test (6.3% vs 6.5%, p=0.98). Serial quantitative coronary angiography analyses identified no significant differences in late lumen loss of in-stent segments between patients with positive patch test and those with negative patch test (0.19+/-0.49 mm vs 0.12+/-0.48 mm, p=0.55). CONCLUSION SES prevent restenosis irrespective of metallic allergy. The classic relationship between metallic allergy and in-stent restenosis, seen with bare metal stents, does not appear to arise with DES, possibly because of the immunosuppressive effect of sirolimus.
{"title":"Reply to Letter Regarding Article, \"Sirolimus-Eluting Stents Suppress Neointimal Formation Irrespective of Metallic Allergy\"(Letter to the Editor)","authors":"G. Nakazawa, K. Tanabe, K. Hara","doi":"10.1253/circj.cj-08-0759","DOIUrl":"https://doi.org/10.1253/circj.cj-08-0759","url":null,"abstract":"BACKGROUND\u0000Metallic allergy is associated with restenosis following bare metal stent implantation, but the impact of metallic allergy on the outcome after implantation of drug-eluting stents (DES) has not been investigated.\u0000\u0000\u0000METHODS AND RESULTS\u0000The present study group consisted of 88 consecutive patients (109 lesions) who underwent percutaneous coronary intervention with sirolimus-eluting stents (SES). Follow-up angiography was obtained at 8 months in all patients. At that time, the patients underwent epicutaneous patch tests for nickel, chromate, molybdenum, manganese, and titanium, which were evaluated after 48 h of contact. The patch test was positive in 14 patients (16%) (5 for manganese, 3 for nickel, 1 for chromate, 1 for Nickel and manganese, and 4 for manganese and chromate). The binary restenosis rate in the patients with a positive patch test was similar to those with negative patch test (6.3% vs 6.5%, p=0.98). Serial quantitative coronary angiography analyses identified no significant differences in late lumen loss of in-stent segments between patients with positive patch test and those with negative patch test (0.19+/-0.49 mm vs 0.12+/-0.48 mm, p=0.55).\u0000\u0000\u0000CONCLUSION\u0000SES prevent restenosis irrespective of metallic allergy. The classic relationship between metallic allergy and in-stent restenosis, seen with bare metal stents, does not appear to arise with DES, possibly because of the immunosuppressive effect of sirolimus.","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"16 1","pages":"1722"},"PeriodicalIF":0.0,"publicationDate":"2008-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80904490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We thank Dr Mamkin and colleagues for their comment on our article. 1 The aim of our study was to assess clinical practice in Japan and patients’ outcomes. However, we also stressed that care should be taken when interpreting our findings. As we mentioned in the study limitations, although our multicenter study was prospective in nature, it included a smaller sample size than previous studies from North America. In addition, many confounding factors were not measured in our study, such as differences in patients’ backgrounds and the Japanese healthcare system, which could have influenced the outcome. These could be part of the uncertainties in clinical practice that influence our decision and thus patients’ outcomes. In our study, we tried to adjust for these factors appropriately, although one cannot deny that any such adjustment cannot be always perfect. To find practical and positive solutions for these issues, the ideal study should be prospective in nature and include sufficient number of patients so as to reduce any possible bias and chances of random errors. Now that we have data from different countries, we await better studies that include larger population samples drawn from various countries. We expect that every practicing physician in all countries genuinely provides the best clinical service to patients regardless of their clinical conditions. No doubt, each case and experience is different and peculiar, but collectively, the medical profession could contribute to improvement of quality of care. Towards this goal, as Dr Mamkin and colleagues alluded to, physicians worldwide should work cooperatively to improve the outcome of various medical conditions, including acute myocardial infarction.
{"title":"Reply to Letter Regarding Article, \"Weekend Onset of Acute Myocardial Infarction Does Not Have a Negative Impact on Outcome in Japan\"(Author's Reply)","authors":"K. Matsui, S. Kojima, H. Ogawa","doi":"10.1253/CIRCJ.72.865","DOIUrl":"https://doi.org/10.1253/CIRCJ.72.865","url":null,"abstract":"We thank Dr Mamkin and colleagues for their comment on our article. 1 The aim of our study was to assess clinical practice in Japan and patients’ outcomes. However, we also stressed that care should be taken when interpreting our findings. As we mentioned in the study limitations, although our multicenter study was prospective in nature, it included a smaller sample size than previous studies from North America. In addition, many confounding factors were not measured in our study, such as differences in patients’ backgrounds and the Japanese healthcare system, which could have influenced the outcome. These could be part of the uncertainties in clinical practice that influence our decision and thus patients’ outcomes. In our study, we tried to adjust for these factors appropriately, although one cannot deny that any such adjustment cannot be always perfect. To find practical and positive solutions for these issues, the ideal study should be prospective in nature and include sufficient number of patients so as to reduce any possible bias and chances of random errors. Now that we have data from different countries, we await better studies that include larger population samples drawn from various countries. We expect that every practicing physician in all countries genuinely provides the best clinical service to patients regardless of their clinical conditions. No doubt, each case and experience is different and peculiar, but collectively, the medical profession could contribute to improvement of quality of care. Towards this goal, as Dr Mamkin and colleagues alluded to, physicians worldwide should work cooperatively to improve the outcome of various medical conditions, including acute myocardial infarction.","PeriodicalId":14644,"journal":{"name":"Japanese Circulation Journal-english Edition","volume":"16 1","pages":"865"},"PeriodicalIF":0.0,"publicationDate":"2008-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81701749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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