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Effects of vitamin C supplementation on Chinese sausage-induced liver damage in rats 补充维生素C对腊肠致大鼠肝损伤的影响
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-02 DOI: 10.15586/ijfs.v35i3.2341
Minxian Rong, Yungang Liu, Yiyuan Wang, Hong Deng
Contamination of nitrosamine compounds in Chinese sausages and the relevant hepatoxicity have been reported. This study was conducted to evaluate the effects of vitamin C (VC) supplementation on Chinese sausage contaminated with N-nitrosodimethylamine (NDMA)-induced liver damage and relevant metabolomic changes. Rats were orally administered with Chinese sausage contaminated with NDMA at levels overpassing its safety limit. In some experiments, VC was additionally administered via drinking water to the rats for 25 weeks. Serum samples were collected from the rats for the measurement of the metabolomic profiles by using gas chromatography–mass spectrometry. Compared with the group administered with Chinese sausages alone, in rats with additional VC treatment, all serum biochemical parameters indicating hepatic damage were significantly alleviated, which suggested an improved hepatic function by VC supplementation. Metabonomic analysis of the serum samples showed notable changes in metabolites in VC-supplemented group as compared to that with sausage alone, especially for those involved in the regulation of amino acid or energy or lipid metabolism and/or anti-oxidative function. This study indicates that VC supplement in parallel with long-term exposure to Chinese sausage may attenuate liver damage and promote the recovery of liver function.
中国香肠中亚硝胺类化合物的污染及其肝毒性已被报道。本试验旨在研究补充维生素C (VC)对n -亚硝基二甲胺(NDMA)污染腊肠肝损伤及代谢组学变化的影响。给大鼠口服超过安全限量的NDMA污染的中国香肠。在一些实验中,VC通过饮用水给予大鼠,持续25周。采集大鼠血清样品,采用气相色谱-质谱联用法测定代谢组学特征。与单独给药组相比,VC组大鼠的血清生化指标均明显减轻,表明VC对肝功能有改善作用。血清代谢组学分析显示,与单独食用香肠相比,vc组代谢产物发生了显著变化,尤其是那些参与氨基酸、能量、脂质代谢和/或抗氧化功能调节的代谢产物。本研究提示,在长期食用腊肠的同时补充VC可减轻肝脏损伤,促进肝功能恢复。
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引用次数: 1
Effects of sourdough on rheological properties of dough, quality characteristics and staling time of wholemeal wheat croissants 酵母对全麦牛角包面团流变学特性、品质特性及贮藏时间的影响
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-29 DOI: 10.15586/ijfs.v35i3.2385
R. Chochkov, Miroslav Savov, V. Gotcheva, Maria Papageorgiou, J. Rocha, Vesselin Baev, A. Angelov
The present study aimed to obtain good quality croissants from wholegrain wheat flour using baking sourdoughs prepared from single starter cultures of Pediococcus acidilactici 02P108 (PA), Pediococcus pentosaceus SM2D17 (PP) and Enteroccocus durans 09B374 (ED) as an attempt to overcome the usual negative effects of the wholegrain flour on the characteristics of this specific bakery product group. Results showed that the addition of sourdough in the wholegrain wheat dough had similar performance as that of conventional baker’s yeast regarding the rheological characteristics of dough. The dynamic viscosity of all sourdough-leavened samples remained higher than that of the control sample at all tested shear rates. A positive effect of sourdoughs used on the development of baking dough was observed in terms of specific volume improvement, higher degree of softening, and reduced baking loss. However, these positive effects were found as strain-specific. The use of Enteroccocus durans 09B374-made sourdough showed the most distinguished sensory characteristics and the best results regarding croissant staling during storage. The study demonstrated that sourdoughs used in wholemeal wheat croissant dough had positive effect on the quality characteristics and shelf-life of products. However, strain selection proved as of key importance for the successful production of wholemeal wheat croissants.
本研究旨在利用单一发酵剂培养的酸活性球球菌02P108 (PA)、戊糖球球菌SM2D17 (PP)和durans肠球菌09B374 (ED)发酵酵母,从全麦面粉中获得优质羊角面包,以克服全麦面粉对这一特定烘焙产品群特性的负面影响。结果表明,全麦面团中添加酵母对面团流变学特性的影响与普通面包酵母相似。在所有测试的剪切速率下,所有酵母发酵样品的动态粘度都高于对照样品。酵母对焙烤面团的发展有积极的影响,表现在比体积的改善、软化程度的提高和焙烤损失的减少。然而,这些积极的影响是菌株特异性的。以杜兰enteroccoccus durans 09b374发酵酵母为原料,对牛角面包的保鲜效果最好。研究表明,全麦牛角面包面团中使用的酵母对产品的质量特性和保质期有积极的影响。然而,菌株选择被证明是成功生产全麦羊角面包的关键。
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引用次数: 0
Quality and stability of different seafood products treated with high hydrostatic pressure (HPP) intended for raw consumption 生食用高静水压力(HPP)处理不同海产品的质量和稳定性
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-23 DOI: 10.15586/ijfs.v35i3.2302
Ana Cristina de Aguiar Saldanha Pinheiro, Silvia Tappi, Giacomo Braschi, J. Genovese, F. Patrignani, P. Rocculi
The consumption of raw fish has rapidly increased in recent years, but being a highly perishable product, it is characterised by a very short microbiological shelf life. High hydrostatic pressure (HPP) processing is a non-thermal technology has emerged recently as a promising alternative to thermal processing for food pasteurization capable of maintaining fresh-like characteristics and nutritional value. However, the induced changes in product quality should be assessed carefully. The present research aimed to investigate the effect of HPP on different seafood products, namely grey mullet, tiger prawn and rose shrimp, intended for raw consumption. Three pressure levels (400, 500 and 600 MPa) were applied for 10 min. During refrigerated storage, microbiological quality, chemical parameters, colour and texture and fat oxidation were analysed. Results showed that the application of lower pressure was able to inactivate E. coli, pseudomonas and/or positive coagulase staphylococci; however, they were able to recover during storage. In addition, the application of 600-MPa pressure extended the microbiological shelf life by up to 30 days. For all samples, general whitening occurred while the texture was affected in a different way for the three considered species. Fat oxidation was only minimally affected and remained quite low during storage.
近年来,生鱼的消费量迅速增加,但作为一种极易腐烂的产品,它的特点是微生物保质期很短。高静水压力(HPP)加工是一种非热技术,近年来作为热加工的一种有前途的替代食品巴氏杀菌,能够保持新鲜的特性和营养价值。但是,应仔细评估引起的产品质量变化。本研究旨在探讨HPP对不同海产品的影响,即灰色鲻鱼、虎对虾和玫瑰虾,拟用于生食。三种压力水平(400,500和600mpa)施加10分钟。在冷藏期间,分析了微生物质量,化学参数,颜色和质地以及脂肪氧化。结果表明,施加较低的压力能够灭活大肠杆菌、假单胞菌和/或阳性凝固酶葡萄球菌;然而,它们能够在储存期间恢复。此外,600 mpa压力的应用将微生物的保质期延长了30天。对于所有的样品,当纹理以不同的方式受到三种被考虑的物种的影响时,一般的美白都会发生。脂肪氧化只受到最小程度的影响,在储存期间保持相当低的水平。
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引用次数: 1
Ganoderma lucidum extract reverses hepatocellular carcinoma multidrug resistance via inhibiting the function of P-glycoprotein in vitro and in vivo 灵芝提取物通过抑制体内和体外p -糖蛋白的功能逆转肝癌多药耐药
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-12 DOI: 10.15586/ijfs.v35i3.2354
Jing Li, Lin Cao, Cheng Yuan, Zhaojian Jiang, Hongfei Cai, Wendong Xu, Yamin Han, Liang Chen, Qin Zhang, Renwang Jiang, Juyan Liu
Cancer is a leading cause of death globally. Chemotherapy still plays an indispensable role in the clinical treatment of cancer. However, the emergence of multidrug resistance (MDR) has greatly obstructed the further application of chemotherapy agents. Ganoderma lucidum (G. lucidum) is a traditional Chinese medicine as well as an edible mushroom. In this study, we first explored the effect of six extract samples derived from G. lucidum on the cell viability of adriamycin-resistant human hepatocellular carcinoma multidrug-resistant cell subline (HepG-2/ADM). All these samples showed no obvious toxicity to cells; however, only G. lucidum ethanol extract could reverse resistance to doxorubicin and paclitaxel. Then the P-glycoprotein (P-gp) function in hepatocellular carcinoma G2 (HepG-2) and HepG-2/ADM cells was determined after incubated with these samples, and we found that G. lucidum ethanol extract could inhibit P-gp function in vitro. Furthermore, G. lucidum ethanol extract could reverse resistance to paclitaxel in HepG-2/ADM tumor-bearing mice in vivo, while the protein expression level of P-gp was unchanged. Taken together, these results indicated the potential role of G. lucidum ethanol extract in reversing MDR in the clinical treatment of hepatocellular carcinoma.
癌症是全球死亡的主要原因。化疗在癌症的临床治疗中仍然发挥着不可缺少的作用。然而,多药耐药(MDR)的出现极大地阻碍了化疗药物的进一步应用。灵芝(Ganoderma lucidum)是一种中药,也是一种食用菌。在本研究中,我们首次探讨了六种灵芝提取物样品对阿霉素耐药人肝癌多药耐药细胞亚群(HepG-2/ADM)细胞活力的影响。所有样品对细胞均无明显毒性;而只有灵芝乙醇提取物能够逆转对阿霉素和紫杉醇的耐药性。然后用这些样品孵育后测定p -糖蛋白(P-gp)在肝癌G2 (HepG-2)和HepG-2/ADM细胞中的功能,我们发现灵光乙醇提取物在体外可以抑制P-gp的功能。此外,在P-gp蛋白表达水平不变的情况下,灵芝乙醇提取物可在体内逆转HepG-2/ADM荷瘤小鼠对紫杉醇的耐药。综上所述,这些结果表明灵芝乙醇提取物在临床治疗肝癌中具有逆转多药耐药的潜在作用。
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引用次数: 0
Some factors affecting the bioactive substances of lactogenic tea 影响生乳茶生物活性物质的几个因素
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-04 DOI: 10.15586/ijfs.v35i3.2335
S. Siripongvutikorn, Chanisara Kluabpet, Chaninat Anantapan, V. Seechamnanturakit
This study aims to perform the phytochemical screening composition for galactagogue herbs and determining the total phenolic (TPC) and flavonoid contents (TFC). Terpenes, saponins, tannins, alkaloids, phenolics, and flavonoids were found in water extracts of banana inflorescence (Musa sapientum L), white holy basil leaves (Ocimum sanctum L.), rhizomes of Thai ginger (Zingiber officinale Roscoe), and powdered lactogenic product. The results show that the TPC were greater than the TFC for all fresh parts of banana inflorescences. Following the M1 method, fresh banana floret gave the greatest TPC, superior to those with M2 or M3, while the TFC with M1 and M2 methods applied to banana floret was significantly greater than that of banana bracts or banana cores. After harvest and dehydration of the banana inflorescence, TPC and TFC after one-day storage were higher than those at five-days of storage. Meanwhile, TPC and TFC on both fresh and dehydrated white holy basil tended to decrease due to heat intolerance, deterioration, and brewing. In contrast, TPC and TFC of Thai ginger increased on dehydration. The maceration with press-shear force interaction (PAI) pretreatment, and with PAI combined with moist heat, strongly increase the bioactive contents. SEM imaging demonstrated that PAI with moist heat tended to enlarge the micro-pore volume and simultaneously increased pores, resulting in more adsorption of these compounds.
本研究的目的是对半乳糖中草药的植物化学成分进行筛选,并测定总酚(TPC)和类黄酮(TFC)含量。在香蕉花序(Musa sapientum L)、白色圣罗勒叶(Ocimum sanctum L.)、泰国生姜根茎(Zingiber officinale Roscoe)和粉状乳制品的水提取物中发现了萜烯、皂苷、单宁、生物碱、酚类和黄酮类化合物。结果表明,香蕉花序各新鲜部位的TPC均大于TFC。在M1法之后,新鲜香蕉小花的TPC最大,优于M2或M3法,而M1和M2法应用于香蕉小花的TFC显著大于香蕉苞片或香蕉核。香蕉花序在收获和脱水后,贮藏一天后的TPC和TFC高于贮藏五天时。同时,新鲜和脱水白圣罗勒的TPC和TFC由于耐热、变质和酿造而趋于降低。相反,泰国生姜的TPC和TFC在脱水后增加。挤压-剪切力相互作用(PAI)预处理的浸渍,以及PAI与湿热相结合的浸渍,大大提高了生物活性含量。SEM成像表明,湿热条件下的PAI倾向于扩大微孔体积,同时增加孔隙,导致这些化合物更多地被吸附。
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引用次数: 1
Grape-based traditional foods produced in Turkey 土耳其生产的葡萄传统食品
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-02 DOI: 10.15586/ijfs.v35i3.2339
Simge Aktop, P. Şanlıbaba, Yalçın Güçer
Turkey is considered the gene centre of the vine, and it has remained one of the most important trading centres of viticulture and grape-based foods for a long time. The grapes grown in Anatolia and the foods obtained by processing these grapes contribute greatly to the economy of the nation. In addition to economic outcomes, grape-based traditional foods provide anti-carcinogenic, anti-inflammatory, antioxidant and cardiovascular disease–preventing benefits when consumed. A few examples of these grape-based traditional foods are molasses, wine, Turkish Rakı, hardaliye and pestil. In this review, the production processes of certain grape-based Turkish traditional foods are summarized.
土耳其被认为是葡萄的基因中心,长期以来一直是葡萄栽培和葡萄食品最重要的贸易中心之一。种植在安纳托利亚的葡萄和通过加工这些葡萄获得的食物对国家经济做出了巨大贡献。除了经济效益外,以葡萄为基础的传统食品还具有抗癌、抗炎、抗氧化和心血管疾病的功效,食用后还能预防疾病。这些以葡萄为基础的传统食品的几个例子是糖蜜、葡萄酒、土耳其Rakı、hardaliye和鼠疫。在这篇综述中,总结了某些以葡萄为基础的土耳其传统食品的生产工艺。
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引用次数: 0
Anti-dyslipidemic and anti-hypercholesteremic effects of concoction juice: A randomized, double-blind, placebo controlled trial 调制果汁的抗血脂异常和抗高胆固醇血症作用:一项随机、双盲、安慰剂对照试验
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-08-01 DOI: 10.15586/ijfs.v35i3.2381
Wajiha Saeed, Shahid Mahmood, G. Mueen-ud-Din, Muhammad Yousaf Quddoos
Globally, dyslipidemia is an alarming condition, which may cause death. However, its country-wise ratio varies. In Pakistan, it is about 16–20% in both men and women. Dyslipidemia can be defined as the up level quantity of lipids in blood than the average value. The treatment of dyslipidemia can be done by dietary interventions with indigenous sources. The (Concoction) juice has the ability to reduce the low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGs). and raise the high-density lipoprotein (HDL) level. For efficacy studies, dyslipidemic females (n = 1010) were approached in different clinics and hospitals of Sargodha. They were approached with biomarkers, that is, lipidemic profile, TC, HDL, urea, creatinine, and TGs. A total of 85 females were selected and they were divided into three groups (T0, L1 and M1). T0 is an experimental (control) group, T1 group has -dyslipidemic patients treated with lab-made juice, and M1 has dyslipidemic patients treated with -market products. After 120 days of treatment, the data were analyzed statistically to validate the results of the study. The -anthropometric and dietary intake was assessed by dyslipidemic volunteers. A significant level of -dyslipidemic biomarker was found in L1. The down level was found in TC (216-184 mg/dL), TGs (215.54-138.46 mg/dL), and LDL (145.64-134.34 mg/dL), and raised level was found in HDL (44.15-54.43 mg/dL). Other parameters that showed a -downward trend were urea (12.73-11.15 mg/dL), uric acid (6.12-5.38 mg/dL), creatinine (1.02-1.0 mg/dL), ALT (55-34 u/l), AST (47-27 u/l), ALP (91.63-83.76 IU/L), bilirubin (0.65 to 0.57 mg/dl), RBCs, WBCs, and Hb. Based on these results, it is concluded that lab-made concoction L1 showed best results overall and is also appropriate and cost effective and further research has to be done on a large scale.
在全球范围内,血脂异常是一种令人担忧的疾病,可能导致死亡。然而,其国家比例各不相同。在巴基斯坦,男性和女性的这一比例约为16-20%。血脂异常可以定义为血液中脂质含量高于平均值。血脂异常的治疗可以通过当地来源的饮食干预来完成。浓缩果汁具有降低低密度脂蛋白(LDL)、总胆固醇(TC)和甘油三酯(TG)的能力。并提高高密度脂蛋白(HDL)水平。对于疗效研究,在Sargodha的不同诊所和医院接触了血脂异常的女性(n=1010)。他们用生物标志物进行了研究,即血脂、TC、HDL、尿素、肌酐和TGs。共选择85名女性,将她们分为三组(T0、L1和M1)。T0是一个实验(对照)组,T1组有-名血脂异常患者用实验室制造的果汁治疗,M1有-名脂异常患者用市场产品治疗。治疗120天后,对数据进行统计学分析,以验证研究结果。由血脂异常的志愿者评估人体测量和饮食摄入量。在L1中发现了显著水平的血脂异常生物标志物。TC(216-184mg/dL)、TG(215.54-138.46mg/dL)和LDL(145.64-134.34mg/dL。其他呈下降趋势的参数包括尿素(12.73-11.15 mg/dL)、尿酸(6.12-5.38 mg/dL。基于这些结果,得出的结论是,实验室制造的混合物L1总体上显示出最佳的结果,也是合适的,并且具有成本效益,还需要进行大规模的进一步研究。
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引用次数: 0
Content of selected polyphenolic substances in parts of grapevine 葡萄部分多酚类物质的含量
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-07-19 DOI: 10.15586/ijfs.v35i3.2298
Lenka Jurasová, T. Juríková, M. Baroň, J. Sochor
This review provides an overview of the variety of occurrences, content, extraction and health effects of selected polyphenolic compounds associated with different parts of grapevine (seeds, peel, pulp and stems). The review provides a brief characterisation of grape parts, the content of polyphenolic compounds and their extraction together with their graphical forms of presentation and diversity as determined by different studies. The content of individual polyphenolic compounds differed with studies. Effects of different factors were evident in both growing style and geographical location of vineyards as well as extraction methods and analytical conditions.
本文综述了葡萄藤不同部位(种子、果皮、果肉和茎)中多酚类化合物的种类、含量、提取及其对健康的影响。本文简要介绍了葡萄各部分的特征,多酚类化合物的含量及其提取方法,以及不同研究确定的葡萄多酚类化合物的图示形式和多样性。个别多酚类化合物的含量与研究结果不同。不同因素对葡萄的生长方式和地理位置、提取方法和分析条件都有明显的影响。
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引用次数: 0
Quality changes during storage in Thai indigenous leafy vegetable, Liang leaves (Gnetum gnemon var. tenerum) after different preparation methods 泰国乡土叶菜梁叶(Gnetum gnemon var. tenerum)不同制备方法贮藏过程中品质的变化
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-07-10 DOI: 10.15586/ijfs.v35i3.2346
S. Siripongvutikorn, W. Usawakesmanee, S. Pisuchpen, Nicha Khatcharin, Chanonkarn Rujirapong
Liang or Gnetum gnemon var. tenerum, an indigenous southern vegetable has recently attracted increasing interest due to its high nutritional value, creamy taste and lack of smell. The leaves with or without stem are washed with chlorinated water at 100 ppm for 15 min, stored at 4°C and investigated for physiochemical, chemical and sensory evaluations over time. Total phenolic and flavonoid contents were higher in treatments with stems (P < 0.05). Washing significantly increased moisture content and water activity (aw) in all treatments (P < 0.05). In addition, washing resulted in significantly higher DPPH and ABTS activity (P < 0.05). However, washing and stem detachment had no effect on sensory and physicochemical qualities. The sensory score of the 8-days stored sample was comparable to the fresh one (Day 0).
梁(Gnetum gnemon var.tenerum)是一种南方本土蔬菜,由于其高营养价值、奶油味和无气味,最近引起了人们越来越多的兴趣。将带茎或不带茎的叶片用100ppm的氯化水洗涤15分钟,在4°C下储存,并随着时间的推移进行理化、化学和感官评估。总酚和黄酮含量在有茎处理中较高(P<0.05)。洗涤显著提高了所有处理的水分含量和水活性(aw)(P<0.01)。此外,洗涤显著提高DPPH和ABTS活性(P<0.001)。但洗涤和脱茎对感官和理化品质没有影响。储存8天的样品的感官评分与新鲜样品(第0天)相当。
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引用次数: 0
A pre-competitive research on frozen gnocchi: quality evaluation and market survey 冷冻意大利面团的赛前研究:质量评价和市场调查
IF 2.6 4区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-06-20 DOI: 10.15586/ijfs.v35i2.2269
A. Stasi, Antonietta Baino
This research was aimed to evaluate quality and safety of five formulations of gnocchi, namely, traditional, tomato-basil, pumpkin, spinach, with cauliflower pieces, and stuffed with cheese, to be marketed in a frozen state. An online survey was performed to assess the consumer desires and willingness to buy these new products in order to assess consumer preferences and targets and verify whether fresh and frozen gnocchi could become market substitutes or complements. The results highlighted that frozen gnocchi were a good product under different points of view and characteristics of an ideal consumer.
本研究旨在评估传统、番茄罗勒、南瓜、菠菜、花菜片和奶酪填充五种冷冻状态下面市的土豆团子的质量和安全性。我们进行了一项在线调查,评估消费者购买这些新产品的欲望和意愿,以评估消费者的偏好和目标,并验证新鲜和冷冻团子是否可以成为市场的替代品或补充。结果表明,在不同的观点和理想消费者的特征下,冷冻团子是一种好产品。
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引用次数: 0
期刊
Italian Journal of Food Science
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