JACC. Heart failure最新文献

{"title":"BMI in HFpEF","authors":"Jennifer E. Ho MD , Sanjeeb S. Bhattacharya MD","doi":"10.1016/j.jchf.2025.102826","DOIUrl":"10.1016/j.jchf.2025.102826","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102826"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145704308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undetected Heart Failure in Tertiary Care/Cardiology in Switzerland","authors":"Klara Rumora MD , Christian Puelacher MD, PhD , Mirjam Pargger MD, PhDc , Desiree Wussler MD , Ivo Strebel PhD , Noemi Glarner MD, PhD , Michael J. Zellweger MD , Danielle M. Gualandro MD, PhD , Otmar Pfister MD , Christian Mueller MD","doi":"10.1016/j.jchf.2025.102733","DOIUrl":"10.1016/j.jchf.2025.102733","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102733"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145374178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Medical Therapy Optimization in Cardiovascular-Kidney-Metabolic Clinical Trials","authors":"Ankeet S. Bhatt MD, MBA, ScM , Diana De Oliveira-Gomes MD , Mona Fiuzat PharmD , Muthiah Vaduganathan MD, MPH , Carine E. Hamo MD, MHS , Norman Stockbridge MD, PhD , Javed Butler MD, MPH, MBA , Mitchell Psotka MD, PhD , William T. Abraham MD , Darren K. McGuire MD, MHSc , Trejeeve Martyn MD, MSc , Barry H. Greenberg MD , Christopher M. O’Connor MD , Scott D. Solomon MD","doi":"10.1016/j.jchf.2025.102727","DOIUrl":"10.1016/j.jchf.2025.102727","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102727"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145382709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanically Reducing Cardiac Preload With the preCARDIA System in Acutely Decompensated Heart Failure","authors":"Rayan Yousefzai MD ,&nbsp;Arvind Bhimaraj MD ,&nbsp;Michael S. Kiernan MD, MPH ,&nbsp;Jacob Abraham MD ,&nbsp;Irakli Gorgoshvili MD ,&nbsp;Ryan J. Tedford MD ,&nbsp;Shashank Desai MD ,&nbsp;Esther E. Vorovich MD ,&nbsp;Keith H. Benzuly MD ,&nbsp;David Miranda MD ,&nbsp;Manreet K. Kanwar MD ,&nbsp;Andrew J. Sauer MD ,&nbsp;Debbie A. Rinde-Hoffman MD ,&nbsp;Ioana Dumitru MD ,&nbsp;Jaime Hernandez-Montfort MD ,&nbsp;Nima Aghili MD ,&nbsp;Farooq H. Sheikh MD ,&nbsp;Anupam Basuray MD ,&nbsp;Jason Bodnar PhD ,&nbsp;Jerry Curran PhD ,&nbsp;Navin K. Kapur MD","doi":"10.1016/j.jchf.2025.102841","DOIUrl":"10.1016/j.jchf.2025.102841","url":null,"abstract":"<div><h3>Background</h3><div>The preCARDIA device is a novel intervention designed to mechanically reduce cardiac filling pressures in patients with acute decompensated heart failure (ADHF) by regulating flow through the superior vena cava.</div></div><div><h3>Objectives</h3><div>The VENUS-HF (SVC Occlusion in Subjects With Acute Decompensated Heart Failure; <span><span>NCT03836079</span><svg><path></path></svg></span>) Early Feasibility Study tested the safety and feasibility of the next-generation preCARDIA system, which includes updates to the sheath, catheter, and console.</div></div><div><h3>Methods</h3><div>In a multicenter, prospective, single-arm safety and feasibility study, 60 subjects with ADHF received preCARDIA support for up to 24 hours. Primary and secondary endpoints testing the safety and technical feasibility of the device were analyzed.</div></div><div><h3>Results</h3><div>Freedom from device- or procedure-related major adverse events was observed in 98.3% (n = 59/60), and successful device deployment and removal in all subjects (N = 60). No statistically significant difference in major adverse events was observed between recipients of the original (0%, n = 0/30) and newest (3.3%, n = 1/30) generation preCARDIA devices. In subjects with 24 ± 3 hours of preCARDIA duration (n = 52), paired right atrial and pulmonary capillary wedge pressures decreased by 23% (18 ± 6 vs 11 ± 6 mm Hg, <em>P</em> &lt; 0.0001) and 18% (30 ± 8 vs 24 ± 9 mm Hg, <em>P</em> &lt; 0.0001), respectively, from baseline to end of device use. Compared with 24 hours before device initiation, net urine output increased during the 24-hour period during device use (−1.5 ± 0.9 vs −3.4 ± 2.4 L, <em>P</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Use of the preCARDIA system in patients with ADHF was feasible and well tolerated, with early exploratory signals of significantly reduced cardiac filling pressures and increased urine output. These findings provide a foundation for larger, prospective studies, such as the upcoming COR-ADHF (Cardiovascular UnlOading with preCARDIA in Acute Decompensated Heart Failure) trial, to determine clinical efficacy. (SVC Occlusion in Subjects With Acute Decompensated Heart Failure [VENUS-HF]; <span><span>NCT03836079</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102841"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145731054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-LVAD tMCS","authors":"Parsa Jahangiri BSc,&nbsp;Yuxiang Luo MD,&nbsp;Kadir Caliskan MD, PhD","doi":"10.1016/j.jchf.2025.102896","DOIUrl":"10.1016/j.jchf.2025.102896","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102896"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full issue PDF","authors":"","doi":"10.1016/S2213-1779(26)00055-7","DOIUrl":"10.1016/S2213-1779(26)00055-7","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102956"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147427293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Use of Inotropic Support in Cardiogenic Shock","authors":"Jonathan Grinstein MD ,&nbsp;Van-Khue Ton MD, PhD ,&nbsp;Sara Kalantari MD ,&nbsp;Jennifer A. Cowger MD, MS ,&nbsp;Manreet Kanwar MD","doi":"10.1016/j.jchf.2025.102725","DOIUrl":"10.1016/j.jchf.2025.102725","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102725"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145374184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proteome-Wide Genetic Investigation of Kidney Function in Heart Failure With Preserved Ejection Fraction","authors":"Karim Kohansal Vajargah MD ,&nbsp;Marie-Joe Dib PhD ,&nbsp;Hamed Tavolinejad MD ,&nbsp;Payman Zamani MD, MTR ,&nbsp;A. Mark Richards MD, PhD ,&nbsp;Douglas L. Mann MD ,&nbsp;Ernst Rietzschel MD, PhD ,&nbsp;Vanessa van Empel MD, PhD ,&nbsp;Stephen Burgess PhD ,&nbsp;Thomas P. Cappola MD, SM ,&nbsp;Julio A. Chirinos MD, PhD","doi":"10.1016/j.jchf.2025.102771","DOIUrl":"10.1016/j.jchf.2025.102771","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102771"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145559691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guideline-Directed Medical Therapy for Patients With a Left Ventricular Assist Device","authors":"Palak Shah MD, MS,&nbsp;Shashank S. Sinha MD, MSc","doi":"10.1016/j.jchf.2025.102853","DOIUrl":"10.1016/j.jchf.2025.102853","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102853"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145902524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Policy Changes for Progress","authors":"Brian Wayda MD ,&nbsp;Corbin E. Goerlich MD ,&nbsp;Alexander K. Karius MD ,&nbsp;Kiran K. Khush MD, MAS","doi":"10.1016/j.jchf.2026.102955","DOIUrl":"10.1016/j.jchf.2026.102955","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"14 3","pages":"Article 102955"},"PeriodicalIF":11.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}