Journal de pharmacie de Belgique最新文献

It is not unusual for a pharmacist to get a prescription to deliver a "kit for euthanasia", without further explanation. However, such a kit is not available. Which products and materials are necessary to perform euthanasia? What are the conditions to which the prescription and delivery has to comply? This article summarizes what you need to know.

Purpose: In France, efforts to optimize prescribing of proton-pump inhibitors (PPIs) are rare. Various studies have shown that the prescription of these drugs is excessive. This has consequences regarding costs and iatrogenesis. The objective of this study was to describe the type of drug related problems (DRP) and pharmaceutical interventions reported by pharmacists practicing in a university hospital.

Methods: Drug related problems and pharmaceutical interventions (PI) made, were recorded on a database. They were classified according to the grid code of the French Society of Clinical Pharmacy.

Results and discussion: Over a 3 years period, 132.890 prescriptions were analysed. 15.347 generated PI. Among them 701 (4.6%) concerned PPIs. Most frequently reported problems were: lack of indication or patients without a documented indication (24.4%), drug-drug interactions (22.4%) and inappropriate route or mode of administration (19.8%). Discontinuation has been proposed in 40.5% of cases, followed by substitution (22.0%) and dosage titration (17.3%). Physicians modified the prescription according to 51.3% of PI. The main PI, discontinuation therapy, is associated with over-prescription of this drug class. Nevertheless, the rate of DRP recorded (0.5%) is low compared to the high exposure of patients on PPIs and misuse (or overuse?) reported in the literature.

Conclusion: PI made during the analysis of prescription contributes to rationalizing the use of PPIs. The action of the pharmacist must be strengthened through training of health professionals, and communication strategies to improve practices.

Under the presidency of prof. H. Depypere (UZ Ghent) and Prof. P. Simon (ULB Erasme) a Belgian panel of thirteen experts (gynecologists, representatives of universities and scientific associations for gynecology-obstetrics) reached a consensus on the use of intrauterine systems, both copper IUDs as hormone IUDs, in nultiparous women.

The last forty years have witnessed major improvements in the survival of pediatric cancer patients with an evolution of acute tymphoblastic leukemia as an untreatable disease to acute lymphoblastic leukemia with a survival rate of more than 90%. This has become possible due to improvements in the various modalities of cancer therapy and supportive care. The aim of this commentary is to give an overview of the history of pharmacological treatment for children with acute Lymphoblastic leukemia.

This article discusses some infectious diseases characterized by eruptions, frequently seen in children. Based on the symptoms, the pharmacy team is able to know the possible cause of the eruptions, to refer if necessary, and to optimize the pharmaceutical care for the patients. Besides general advice regarding eruption and fever, specific advice is given for each disease focusing on hygienic measures and prevention of further infection.

REMED stands for a "MEDication Errors Review". The REMED method aims at implementing and monitoring actions to improve patient medical care. This approach is part of the continuing healthcare quality and safety improvement and professional practice evaluation. REMED uses methodology and tools. Thus we use this methodology in the context of a drug errorwhich occurred in the dermatology department of our hospital. After this event description, related to a sensitive drug product, Instanyl (transmucosal fentanyl), the drug error is described, then the different causes are analyzed. These last are numerous and occur at any stage of patient medical care. They must allow us to show actions in order to improve patients' safety.