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New device for assessing the toe-brachial index and a pilot cross-sectional study in diabetic patients. 评估脚趾-肱指数的新装置和糖尿病患者的试点横断面研究。
IF 1 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401042
Thiago Paes de Barros De Luccia, Alexandre Donisete Bensi, Nelson De Luccia, Priscilla Matos Cunha, Lia Maristela da Silva Jacob, Leonardo Servato Sanches Martins de Barros, Julio Maganha Gouvêa, Vívian Mei Matuoka

Background: Blood pressure measurements in the hallux and fingers are important in evaluation of patients with diabetes, obese patients, dialysis patients, and those with peripheral artery disease.

Objectives: In this article, we tested a prototype of an automatic device for measuring systolic pressure in fingers and toes, combining optical plethysmography and a pressure sensor, with a cuff encircling the finger or toe, and controlled by a microcontroller.

Methods: The prototypes (a total of 3 identical devices) were tested for initial validation (with a group of participants who already had symptoms of peripheral arterial disease [PAD], n=30) and also in clinical comparisons between controls (n=15) and participants with diabetes (n=15). The following variables were tested: Ankle-brachial index; Toe-finger index; Toe-brachial index, and toe pressure in isolation. For validation, the toe pressure in isolation was measured with two devices (the prototype under test and the SysToe® device), to analyze the correlation between the two measurements.

Results: The correlation between the two devices was strong (R=0.88) in the group with symptoms of PAD. Toe-brachial index was lower in patients with diabetes than in control participants (p=0.005) as was the Toe-finger index (p=0.03), however, the Ankle-brachial index was similar in these two groups (p=0.92).

Conclusions: The findings show the feasibility of the device for measuring finger and toe pressures, and possibly indicate greater sensitivity for detecting early-stage arterial disease using this type of measurement.

背景:拇和手指的血压测量对于糖尿病患者、肥胖患者、透析患者和外周动脉疾病患者的评估很重要。目的:在本文中,我们测试了一种用于测量手指和脚趾收缩压的自动装置的原型,该装置结合了光学体积脉搏仪和压力传感器,并由微控制器控制。方法:对原型(共3个相同的装置)进行初步验证(已出现外周动脉疾病[PAD]症状的一组参与者,n=30),并在对照组(n=15)和糖尿病参与者(n=15)之间进行临床比较。测试了以下变量:踝臂指数;Toe-finger指数;脚趾肱指数和脚趾压力为了验证,使用两个设备(待测原型和SysToe®设备)测量隔离脚趾压力,以分析两个测量值之间的相关性。结果:两种器械在有PAD症状组相关性较强(R=0.88)。糖尿病患者的脚趾-肱指数低于对照组(p=0.005),脚趾-手指指数也低于对照组(p=0.03),然而,两组的踝-肱指数相似(p=0.92)。结论:研究结果表明该装置测量手指和脚趾压力的可行性,并可能表明使用这种测量方法检测早期动脉疾病的灵敏度更高。
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引用次数: 0
Systematic review and meta-analysis of the impact of diabetes mellitus on chronic venous insufficiency. 糖尿病对慢性静脉功能不全影响的系统回顾和荟萃分析。
IF 1 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202500062
Alex Carlos Ferreira de Castro, Anderson Veiga Barbosa, David Fonseca Lima, João Vitor Rodrigues Vidal, José Maciel Caldas Reis, Saul Rassy Carneiro

The systematic review with meta-analysis aimed to investigate the occurrence of Chronic Venous Insufficiency (CVI) in patients with Type II Diabetes Mellitus (T2DM). The guiding research question was structured using the PECOT framework (P: population; E: exposure; C: comparison; O: outcome; T: type of study), and the risk of bias was assessed using the ROBIS-I tool. A total of four studies were included in the analysis. The findings revealed that the prevalence of CVI in patients with T2DM was 55%, with a prevalence ratio of 1.51 (95% CI: 1.01 to 2.26). These results suggest that individuals with T2DM have a significantly higher prevalence of CVI compared to those without the condition. However, the review identified several limitations, such as the scarcity of longitudinal studies and variability in the diagnostic criteria for CVI among the included studies. The authors conclude that further research is warranted to address these gaps and deepen understanding of the relationship between T2DM and CVI.

本系统综述与荟萃分析旨在探讨慢性静脉功能不全(CVI)在2型糖尿病(T2DM)患者中的发生情况。指导性研究问题采用PECOT框架(P: population;艾凡:曝光;C:比较;O:结果;T:研究类型),并使用ROBIS-I工具评估偏倚风险。共有四项研究被纳入分析。研究结果显示,T2DM患者CVI患病率为55%,患病率比为1.51 (95% CI: 1.01 ~ 2.26)。这些结果表明,T2DM患者的CVI患病率明显高于非T2DM患者。然而,该综述发现了一些局限性,如纵向研究的缺乏和纳入研究中CVI诊断标准的可变性。作者得出结论,需要进一步的研究来解决这些差距,并加深对T2DM和CVI之间关系的理解。
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引用次数: 0
Migration of atrial septal occluder device to the thoracic aorta: case report. 房间隔封堵器移至胸主动脉1例。
IF 1 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401062
Felipe Carrasco Ferreira Dionisio, Pedro Henrique Amaral Ângelo da Silva, Bruno Lima Moreira, Augusto Kreling Medeiros

Atrial septal defect (ASD) is a common cardiac defect with significant implications if left untreated. Although open heart surgery is the traditional approach, transcatheter closure devices, such as the Amplatzer™ Septal Occluder Device, have gained prominence due to advantages like shorter hospital stays and reduced costs. Among potential complications, device migration is a rare complication, with an incidence of 0.5 to 1.1%. We report a rare case of migration of an Amplatzer™ device in an asymptomatic patient, diagnosed 6 months after its implantation. After detecting the issue, the medical team opted for percutaneous device removal followed by open surgery to correct the ASD. In conclusion, managing Amplatzer™ device embolization requires careful consideration of the patient's circumstances and device anatomy. This case highlights the importance of correlating clinical and imaging findings when selecting the management approach and assessing the feasibility of a less invasive approach in cases of late migration.

房间隔缺损(ASD)是一种常见的心脏缺陷,如果不及时治疗,会产生重大影响。虽然心内直视手术是传统的方法,但经导管封闭装置,如Amplatzer™中隔闭塞装置,由于其缩短住院时间和降低成本等优势而获得了突出的地位。在潜在的并发症中,器械移位是一种罕见的并发症,发生率为0.5 - 1.1%。我们报告一个罕见的病例迁移的Amplatzer™装置在无症状患者,诊断6个月后其植入。在发现问题后,医疗团队选择了经皮切除装置,然后进行开放手术来纠正ASD。总之,管理Amplatzer™设备栓塞需要仔细考虑患者的情况和设备的解剖结构。该病例强调了在选择治疗方法和评估微创治疗晚期迁移的可行性时,将临床和影像学结果相关联的重要性。
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引用次数: 0
Treatment of type IIIa endoleak and 7-year follow-up: case report. IIIa型渗漏治疗及7年随访1例。
IF 1 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400192
Luiz Ronaldo Godinho Pereira, Keller Soares Ávila, Vinicius Oliveira Godoi, Leonardo Augusto D'Avila Gonçalves, Rafael Fortes, Marcelo Adriano de Assis Hudson, Daniel Mendes Pinto

Type III endoleaks are characterized by a problem with the endograft structure, such as fracture of the metallic structure, separation, or rupture. They constitute a rare complication, occurring in 2.1% of patients after treatment of abdominal aortic aneurysm by endovascular repair, with higher incidence in first and second generation endografts, and can occur early (after 30 days) or later. This type III classification is subdivided into IIIa -modular separation of components - and IIIb - mesh fracture or rupture involving the endograft. This case report describes an asymptomatic patient who had previously undergone infrarenal abdominal aortic aneurysm repair and underwent follow-up computed tomography which found a type IIIa endoleak with separation of the main body from the proximal extension. A second endovascular intervention was performed to seal the endoleak and correct the aneurysm.

III型内漏的特点是内接枝结构出现问题,如金属结构断裂、分离或破裂。它们是一种罕见的并发症,在经血管内修复治疗腹主动脉瘤的患者中发生率为2.1%,在第一代和第二代内移植物中发病率较高,可早发生(30天后),也可晚发生。这种类型分为IIIa -组件模块化分离-和IIIb -涉及内移植物的网状骨折或破裂。本病例报告描述了一位无症状的患者,他之前接受了肾下腹主动脉瘤修复术,并在随访的计算机断层扫描中发现了一个IIIa型内漏,主体与近端延伸分离。进行第二次血管内介入以封闭腔内渗漏并矫正动脉瘤。
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引用次数: 0
Prevalence of rare visceral aneurysms. 罕见内脏动脉瘤的患病率。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202500412
Jamile Gomes Pereira de Barros, Luana Vieira de Medeiros Santana, Maria Clara Gomes Pontes, Letícia Lemos Belo, Bárbara Rocha Rodrigues Cox Coelho, Lucas Mendes Reis de Moura, Pedro Pereira Tenório
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引用次数: 0
Cost of radiofrequency ablation for chronic venous insufficiency: a pilot study of 9 cases at a teaching hospital in Brazil. 射频消融术治疗慢性静脉功能不全的费用:巴西一家教学医院9例病例的初步研究。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401722
Ana Luiza Carvalho Sartoreli, Henrique Capistrano Dos Santos, Thais Keltke Santos Felippe, Júlio César Souza Diniz, Luiz Baldini, Gustavo Muçouçah Sampaio Brandão, Michel Nasser

Background: While radiofrequency ablation (RFA) is increasingly used to treat saphenous vein incompetence, its adoption in Brazil may have been hindered by the lack of evidence demonstrating sufficient added value to justify its cost-effectiveness.

Objectives: To perform RFA in 9 patients with lower extremity varicose veins and determine the procedural costs per patient at a Brazilian teaching hospital.

Methods: Nine single-use RFA catheters were purchased by the teaching hospital affiliated with our institution and used in this pilot study. Direct and indirect costs were calculated as sums of the respective cost components of the procedure based on values from the federal government's price panel. To illustrate the potential cost-effectiveness of RFA, these costs were compared to those of 9 saphenectomy procedures performed on the same day as the RFA procedures. All analyses were descriptive, with no formal statistical testing.

Results: The mean operating room hourly rate for RFA was 127.50 BRL. The costs of anesthetics/medications, materials, and single-use catheter per patient were 32.63 BRL, 81.49 BRL, and 1600.00 BRL, respectively. Patients were absent from work for < 15 days (mean, 11.44 days), not incurring sick leave payments from the Social Security Administration. The total mean cost for RFA was lower than that of same-day saphenectomy (1841.62 BRL vs 2045.40 BRL).

Conclusions: This pilot study provided essential insights into resource utilization at a Brazilian teaching hospital, with the goal of improving treatment efficiency and ensuring the best cost-benefit ratio for patients.

背景:虽然射频消融(RFA)越来越多地用于治疗隐静脉功能不全,但由于缺乏足够的证据证明其成本效益,其在巴西的应用可能受到阻碍。目的:在巴西一家教学医院对9例下肢静脉曲张患者进行射频消融治疗,并确定每位患者的手术费用。方法:从我院附属教学医院购买9根一次性RFA导管用于本试验。直接成本和间接成本是根据联邦政府价格小组的价值计算的程序中各自成本组成部分的总和。为了说明RFA的潜在成本效益,将这些成本与同一天进行的9例隐骨切除术的成本进行了比较。所有的分析都是描述性的,没有正式的统计检验。结果:RFA的手术室平均小时收费为127.50 BRL。麻醉/药物费用、材料费用、单次使用导管费用分别为32.63、81.49、1600.00巴西雷亚尔。患者缺勤时间小于15天(平均11.44天),未从社会保障局获得病假工资。RFA的总平均费用低于当日隐骨切除术(1841.62巴西雷亚尔vs 2045.40巴西雷亚尔)。结论:这项初步研究为巴西一家教学医院的资源利用提供了重要的见解,目的是提高治疗效率,确保患者的最佳成本效益比。
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引用次数: 0
Outpatient treatment of varicose veins with endolaser in clinic vs. hospital: cost-benefit and safety assessment. 门诊治疗静脉曲张在诊所与医院:成本效益和安全性评估。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401602
Camila Biedler Giordani, Mateus Picada Correa, Luiza Brum Borges, Vitória Cerbaro Farias, Renan Camargo Puton, Jaber Nashat Saleh, Rafael Stevan Noel, Julio Cesar Bajerski

Background: Varicose disease is a common pathology among the population, with an incidence of about 38%. In Brazil, it affects 45% of women and 30% of men. Currently, endovenous thermal ablation (EVTA) of the saphenous vein is the method of choice in the treatment of varicose veins. As a minimally invasive procedure that promotes quick recovery and does not require hospitalization, it can be performed on an outpatient basis.

Objectives: To evaluate the safety and cost-benefit of outpatient varicose vein treatment in a clinic compared to the same procedure performed in a hospital environment.

Methods: A uncontrolled retrospective transversal study of case series evaluated a random group of 50 patients undergoing EVTA for the treatment of varicose disease by the same group of vascular surgeons. Twenty-five underwent the procedure in a tertiary hospital environment and 25 on an outpatient basis. The average costs of room fees and materials from both groups were analyzed and statistically compared with the Student's t-test. Intraoperative and postoperative complications were assessed.

Results: The average hospital cost of the procedure was R$ 1391.99 (± 280.8) in the hospital and R$ 1593.40 (± 99.53) in the clinic. The Student's t-test showed a significant difference with p=0.02. No patient had complications either intraoperatively or postoperatively.

Conclusions: Outpatient surgery, despite having a statistically higher cost than hospital surgery in Brazil, is safe and has a positive cost-benefit for the patient.

背景:静脉曲张是人群中一种常见的疾病,发病率约为38%。在巴西,它影响了45%的女性和30%的男性。目前,隐静脉热消融(EVTA)是治疗静脉曲张的首选方法。作为一种微创手术,促进快速恢复,不需要住院治疗,可以在门诊进行。目的:评价门诊静脉曲张治疗与医院治疗的安全性和成本效益。方法:一项无控制的回顾性横向研究病例系列评估随机组50例患者接受EVTA治疗静脉曲张疾病由同一组血管外科医生。25人在三级医院接受手术,25人在门诊接受手术。对两组学生的平均住宿费和材料费用进行分析,并采用学生t检验进行统计比较。评估术中及术后并发症。结果:住院平均费用为1391.99雷亚尔(±280.8)元,门诊平均费用为1593.40雷亚尔(±99.53)元。经学生t检验,p=0.02,差异有统计学意义。术中、术后均无并发症发生。结论:在巴西,尽管门诊手术的成本在统计上高于住院手术,但门诊手术是安全的,并且对患者具有积极的成本效益。
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引用次数: 0
Diagnosis of plantar vein thrombosis by vascular ultrasound: a case report. 血管超声诊断足底静脉血栓1例。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-06-16 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400812
Mariana Jordão França, Luciana Akemi Takahashi, Graciliano José França

Plantar vein thrombosis is a vascular disease that affects the medial and/or lateral plantar veins. Its clinical manifestations are generally non-specific. However, it usually presents with pain in the plantar region, edema, and difficulty walking. The disease predominantly affects middle-aged females and is idiopathic in the majority of cases. The most commonly associated risk factors are recent surgical procedures, cancer, use of oral contraceptives, local trauma, and genetic disorders, such as hereditary thrombophilia. The gold standard diagnostic test is vascular ultrasound, evaluating venous compressibility. We report a case of venous thrombosis of the lateral plantar vein diagnosed with vascular ultrasound.

足底静脉血栓形成是一种影响内侧和/或外侧足底静脉的血管疾病。其临床表现一般无特异性。然而,它通常表现为足底疼痛、水肿和行走困难。该病主要影响中年女性,多数病例为特发性。最常见的相关危险因素是最近的外科手术、癌症、口服避孕药的使用、局部创伤和遗传性疾病,如遗传性血栓病。金标准诊断试验是血管超声,评估静脉压缩性。我们报告一例静脉血栓形成的外侧足底静脉诊断血管超声。
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引用次数: 0
Animal model of a bovine pericardial patch for thoracoabdominal aortic aneurysms: step by step. 牛胸腹主动脉瘤心包贴片的动物模型:循序渐进。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-06-13 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401822
Allana Maryel Tobita, Bruno Jeronimo Ponte, Maria Fernanda Cassino Portugal, Anna Paula Weinhardt Baptista, Igor Rafael Sincos, Nelson Wolosker

Background: The treatment of thoracoabdominal aortic aneurysms (TAA) has advanced. Understanding the pathophysiology and surgical approaches to this disease is essential for best therapeutic performance.

Objectives: We aimed to improve previously described methods for creating thoracoabdominal aortic aneurysms in a porcine animal model, reducing surgical procedure time and specimen mortality.

Methods: A total of 18 swine underwent a surgical procedure to create a TAA. An autologous peritoneal patch was used to create the aneurysm in 2 animals, and a bovine pericardial patch was used in the other 16. The animals were followed up postoperatively, and the aneurysm sac was reexamined after 4 weeks. The animals that did not die in the post-operative period were euthanized according to institutional recommendations.

Results: All of the animals underwent laparotomy with retroperitoneal access. Two received an autologous peritoneal patch and 16 received a bovine pericardial patch. Three animals underwent single suprarenal clamping, while 15 underwent sequential clamping. There were no differences in operative time (p=0.207) or total clamping time (p=0.276) between groups. There was a higher mortality rate after 4 weeks in animals that received single clamping (100%) than sequential clamping (26.7%) (p=0.0017).

Conclusions: The experimental model of TAA using a bovine pericardial patch and a sequential clamping technique provided a stable and reliable platform that remains stable and patent for up to 4 weeks. This model can be extremely valuable for assessing new endovascular therapy options in living organisms.

背景:胸腹主动脉瘤(TAA)的治疗已取得进展。了解这种疾病的病理生理学和手术方法对最佳治疗效果至关重要。目的:我们旨在改进先前描述的在猪动物模型中制造胸腹主动脉瘤的方法,减少手术时间和标本死亡率。方法:共有18头猪接受了外科手术以建立TAA。在2只动物中使用自体腹膜贴片来制造动脉瘤,在另外16只动物中使用牛心包贴片。术后随访,术后4周复查动脉瘤囊。术后未死亡的动物根据机构建议实施安乐死。结果:所有动物均行剖腹手术,经腹膜后通路。2人接受自体腹膜贴片,16人接受牛心包贴片。单次肾上夹持3只,连续夹持15只。两组间手术时间(p=0.207)和总夹紧时间(p=0.276)差异无统计学意义。4周后,单次夹紧组的死亡率(100%)高于连续夹紧组(26.7%)(p=0.0017)。结论:采用牛心包补片和顺序夹持技术的TAA实验模型提供了一个稳定可靠的平台,可保持4周的稳定性和专利性。这个模型对于评估活体血管内治疗的新选择是非常有价值的。
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引用次数: 0
Aberrant right subclavian artery: case report and literature review. 右锁骨下动脉异常:1例报告并文献复习。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-06-09 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202300832
Ana Gabriela Fernandes Peixoto Martins, Marco Rafael Lopes da Cunha
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引用次数: 0
期刊
Jornal Vascular Brasileiro
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