R. Badertscher, V. Kilchenmann, A. Liniger, P. Gallmann
{"title":"Determination of 1,4-dichlorobenzene, naphthalene and thymol residues in honey using static Headspace coupled with GC-MS","authors":"R. Badertscher, V. Kilchenmann, A. Liniger, P. Gallmann","doi":"10.3896/IBRA.4.02.3.01","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.3.01","url":null,"abstract":"","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"9 1","pages":"87-92"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78789628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibacterial activity of Royal Jelly against bacteria capable of infecting cutaneous wounds","authors":"M. García, M. Finola, J. Marioli","doi":"10.3896/IBRA.4.02.3.02","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.3.02","url":null,"abstract":"","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"1 1","pages":"93-99"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82233483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Honey samples produced by Apis mellifera, both unifloral and multifloral (i.e. longan, sabsua, lychee, rambutan, sunflower, kapok, sesame, para rubber and wild flowers) from different sources in Thailand were examined for their antibacterial and antifungal activities as well as antioxidant properties. An agar incorporation technique was used to assess the minimum inhibition concentration (MIC) of honey against fourteen species of bacteria (Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli, Micrococcus luteus, Staphylococcus epidermidis, Streptococcus pyogenes, Listeria monocytogenes, Proteus mirabilis, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, Serratia marcescens, Salmonella typhimurium and Propionibacterium acnes) and two species of yeasts (Candida albicans and Saccharomyces cerevisiae). The Folin-Ciocalteu assay was used to measure phenol content and the 2,2-diphenyl-picrylhydrazyl (DPPH) assay was used to determine the scavenging activity of the honey samples. The honey samples were found to inhibit all of the tested bacteria but not the two species of yeasts. Antioxidant properties, determined by average phenol content was in the range of 493.79 ± 34.78 -1,160.39 ± 348.66 mg GAE/kg. The DPPH radical scavenging assay was found to have an IC50 in the range of 5.8 ± 1.55-19.76 ± 6.09 mg/mL.
{"title":"Antimicrobial and antioxidant properties of honeys produced by Apis mellifera in Thailand","authors":"Montra Srisayam, P. Chantawannakul","doi":"10.3896/IBRA.4.02.2.03","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.2.03","url":null,"abstract":"Honey samples produced by Apis mellifera, both unifloral and multifloral (i.e. longan, sabsua, lychee, rambutan, sunflower, kapok, sesame, para rubber and wild flowers) from different sources in Thailand were examined for their antibacterial and antifungal activities as well as antioxidant properties. An agar incorporation technique was used to assess the minimum inhibition concentration (MIC) of honey against fourteen species of bacteria (Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli, Micrococcus luteus, Staphylococcus epidermidis, Streptococcus pyogenes, Listeria monocytogenes, Proteus mirabilis, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, Serratia marcescens, Salmonella typhimurium and Propionibacterium acnes) and two species of yeasts (Candida albicans and Saccharomyces cerevisiae). The Folin-Ciocalteu assay was used to measure phenol content and the 2,2-diphenyl-picrylhydrazyl (DPPH) assay was used to determine the scavenging activity of the honey samples. The honey samples were found to inhibit all of the tested bacteria but not the two species of yeasts. Antioxidant properties, determined by average phenol content was in the range of 493.79 ± 34.78 -1,160.39 ± 348.66 mg GAE/kg. The DPPH radical scavenging assay was found to have an IC50 in the range of 5.8 ± 1.55-19.76 ± 6.09 mg/mL.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"120 1","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87453504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
From September to November during the years between 2004 and 2006, 78 honey samples were collected from ten areas of the Muğla city in western Turkey, Merkez, Milas, Ortaca, Köyceğiz, Marmaris, Fethiye, Yatağan, Bodrum, Ula and Datça where pine honey beekeeping is practiced extensively. Using light microscopy the Number of Honeydew Elements (NHE) and the Number of Total Pollen (NTP) were determined and samples with an NHE / NTP ratio above 4.5 were accepted as high density, superior quality pine honeydew honey. Of the 78, honeys collected, 50 were found to be pine honeydew honeys and were analysed for total phenolic and total favonoids. The mean total phenolic acids of the 50 pine honeys were found to be 155.55 mg GAE/kg, with a minimum of 35.36 mg GAE/kg, and a maximum of 365.94, while the mean total flavonoid content was found to be 22.80 mg QE/kg, with a minimum of 4.80 mg QE/ kg, and a maximum of 54.78 mg QE/kg.
{"title":"Total Phenolic Acid and Total Flavonoid Content of Turkish Pine Honeydew Honey","authors":"Asl, Özkök, B. D'Arcy, K. Sorkun","doi":"10.3896/IBRA.4.02.2.01","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.2.01","url":null,"abstract":"From September to November during the years between 2004 and 2006, 78 honey samples were collected from ten areas of the Muğla city in western Turkey, Merkez, Milas, Ortaca, Köyceğiz, Marmaris, Fethiye, Yatağan, Bodrum, Ula and Datça where pine honey beekeeping is practiced extensively. Using light microscopy the Number of Honeydew Elements (NHE) and the Number of Total Pollen (NTP) were determined and samples with an NHE / NTP ratio above 4.5 were accepted as high density, superior quality pine honeydew honey. Of the 78, honeys collected, 50 were found to be pine honeydew honeys and were analysed for total phenolic and total favonoids. The mean total phenolic acids of the 50 pine honeys were found to be 155.55 mg GAE/kg, with a minimum of 35.36 mg GAE/kg, and a maximum of 365.94, while the mean total flavonoid content was found to be 22.80 mg QE/kg, with a minimum of 4.80 mg QE/ kg, and a maximum of 54.78 mg QE/kg.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"11 1","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82091853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Sánchez, S. Miranda, P. Vit, Antonio J. Rodríguez-Malaver
Laboratorio de Bioquímica Adaptativa, Departamento de Bioquímica, Facultad de Medicina, Universidad de Los Andes, Mérida, Venezuela. Departamento de Biopatología, Facultad de Odontología, Universidad de Los Andes, Mérida, Venezuela. Departamento de Odontología Restauradora, Facultad de Odontología, Universidad de Los Andes, Mérida, Venezuela. Apiterapia y Bioactividad, Departamento de Ciencia de los Alimentos, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela
{"title":"Propolis protects against oxidative stress in human saliva","authors":"N. Sánchez, S. Miranda, P. Vit, Antonio J. Rodríguez-Malaver","doi":"10.3896/IBRA.4.02.2.02","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.2.02","url":null,"abstract":"Laboratorio de Bioquímica Adaptativa, Departamento de Bioquímica, Facultad de Medicina, Universidad de Los Andes, Mérida, Venezuela. Departamento de Biopatología, Facultad de Odontología, Universidad de Los Andes, Mérida, Venezuela. Departamento de Odontología Restauradora, Facultad de Odontología, Universidad de Los Andes, Mérida, Venezuela. Apiterapia y Bioactividad, Departamento de Ciencia de los Alimentos, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"142 1","pages":"72-76"},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86240141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AN APPROACH TO THE APPLICATION OF ROYAL JELLY: ENCAPSULATION OF LYOPHILIZED ROYAL JELLY AND ITS EFFECT ON GLUCOSE METABOLISM IN HUMANS","authors":"K. Munstedt, M. Bohme","doi":"10.3896/IBRA.4.02.1.03","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.1.03","url":null,"abstract":"","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"46 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2010-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89409387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Propolis is a resinous hive product collected by worker bees from various parts of the plants. It is widely used in Indian folk medicine for the treatment of stomach ulcers. The preventive and curative effects of Indian propolis for ulcers were evaluated using models of acute gastric lesions induced by ethanol and indomethacin in rats. Moreover, the effects of ethanolic extract of propolis on gastric content volume, total acidity and pH, using the pylorus ligated model were also evaluated. Animals pretreated with propolis extract showed a significant reduction in lesion index in both ethanol and indomethacin induced ulcer models in a dose dependent manner when compared to the control group. Similarly, post-treatment with propolis (300 mg/kg body weight) for a period of 15 days revealed a statistically significant improvement in the ulcer healing process p <0.05. In the pylorus ligated model, it was observed that the Indian propolis extract displayed an antisecretory activity, which led to a significant reduction in the gastric juice volume, total acidity and pH. These findings indicate that Indian propolis displays both ulcer preventive and ulcer curative properties and provides a scientific rationale for the use of propolis in the traditional medicinal system.
{"title":"Antiulcerogenic and ulcer healing effects of Indian propolis in experimental rat ulcer models","authors":"Iyyam Pillai, M. Kandaswamy, S. Subramanian","doi":"10.3896/IBRA.4.02.1.02","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.1.02","url":null,"abstract":"Propolis is a resinous hive product collected by worker bees from various parts of the plants. It is widely used in Indian folk medicine for the treatment of stomach ulcers. The preventive and curative effects of Indian propolis for ulcers were evaluated using models of acute gastric lesions induced by ethanol and indomethacin in rats. Moreover, the effects of ethanolic extract of propolis on gastric content volume, total acidity and pH, using the pylorus ligated model were also evaluated. Animals pretreated with propolis extract showed a significant reduction in lesion index in both ethanol and indomethacin induced ulcer models in a dose dependent manner when compared to the control group. Similarly, post-treatment with propolis (300 mg/kg body weight) for a period of 15 days revealed a statistically significant improvement in the ulcer healing process p <0.05. In the pylorus ligated model, it was observed that the Indian propolis extract displayed an antisecretory activity, which led to a significant reduction in the gastric juice volume, total acidity and pH. These findings indicate that Indian propolis displays both ulcer preventive and ulcer curative properties and provides a scientific rationale for the use of propolis in the traditional medicinal system.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"45 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2010-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89772433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epidemiologic findings strongly suggest that cancer rates are influenced by environmental factors that can be mitigated to a great extent, for example by a diet rich in polyphenolic/flavonoid compounds. Among natural products, honeybee propolis has been applied for centuries in traditional medicine as well as in diets and supplementary nutrition. Honeybee propolis and its polyphenolic/flavonoid compounds have been known to exhibit biological activity including immunopotentiation, chemopreventive and antitumor effects. In this review we consider the inhibition of tumor growth by honeybee propolis and their polyphenolic/flavonoid compounds as well as the mechanisms involved based on in vivo and in vitro studies. Results have shown that propolis and its polyphenolic compounds exerted an anti-metastatic and antitumor effect in mice and rats and considerable cytotoxicity without cross-resistance in both wild-type and chemoresistant human tumor cell lines. These findings suggest that propolis and their polyphenolic/flavonoid components may serve as a potent adjunct to chemotherapy and radiotherapy in the treatment of cancers. However, further in-depth studies including clinical trials are needed to fully evaluate the value of flavonoids in combination with chemotherapeutic agents for the treatment of human cancers.
{"title":"A review of propolis antitumor action in vivo and in vitro","authors":"N. Oršolić","doi":"10.3896/IBRA.4.02.1.01","DOIUrl":"https://doi.org/10.3896/IBRA.4.02.1.01","url":null,"abstract":"Epidemiologic findings strongly suggest that cancer rates are influenced by environmental factors that can be mitigated to a great extent, for example by a diet rich in polyphenolic/flavonoid compounds. Among natural products, honeybee propolis has been applied for centuries in traditional medicine as well as in diets and supplementary nutrition. Honeybee propolis and its polyphenolic/flavonoid compounds have been known to exhibit biological activity including immunopotentiation, chemopreventive and antitumor effects. In this review we consider the inhibition of tumor growth by honeybee propolis and their polyphenolic/flavonoid compounds as well as the mechanisms involved based on in vivo and in vitro studies. Results have shown that propolis and its polyphenolic compounds exerted an anti-metastatic and antitumor effect in mice and rats and considerable cytotoxicity without cross-resistance in both wild-type and chemoresistant human tumor cell lines. These findings suggest that propolis and their polyphenolic/flavonoid components may serve as a potent adjunct to chemotherapy and radiotherapy in the treatment of cancers. However, further in-depth studies including clinical trials are needed to fully evaluate the value of flavonoids in combination with chemotherapeutic agents for the treatment of human cancers.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"3 1","pages":"1-20"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82263210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antioxidant properties of total ethanolic extract of Indian propolis were investigated in this study, and the antioxidant activity of hexane soluble portion, ethyl acetate soluble portion and ethanol soluble portion of the crude propolis were also determind. Although the alcoholic extract (TEEP) showed moderate antioxidant activity, it was found that ethyl acetate soluble fraction of propolis (EAFP) exhibited superior antioxidant activity to the activity of trolox at the same concentration. Also it showed the maximum DPPH scavenging activity (81%) and NO radical scavenging activity (60%) as compared to the other formulations which were higher. The ethyl acetate soluble fraction was found to exhibit strongest trolox equivalent antioxidant capacity and other free radical scavenging activities. From IC50 values it was deduced that antioxidant compounds were located in the ethyl acetate soluble fraction. Thus Indian propolis was shown to act as a natural antioxidant; these properties may make it useful for pharmaceutical industries and as a food supplement.
{"title":"Antioxidant properties of Indian propolis","authors":"D. Naik, Harshada S Vaidya, B. Behera","doi":"10.3896/IBRA.4.01.4.03","DOIUrl":"https://doi.org/10.3896/IBRA.4.01.4.03","url":null,"abstract":"Antioxidant properties of total ethanolic extract of Indian propolis were investigated in this study, and the antioxidant activity of hexane soluble portion, ethyl acetate soluble portion and ethanol soluble portion of the crude propolis were also determind. Although the alcoholic extract (TEEP) showed moderate antioxidant activity, it was found that ethyl acetate soluble fraction of propolis (EAFP) exhibited superior antioxidant activity to the activity of trolox at the same concentration. Also it showed the maximum DPPH scavenging activity (81%) and NO radical scavenging activity (60%) as compared to the other formulations which were higher. The ethyl acetate soluble fraction was found to exhibit strongest trolox equivalent antioxidant capacity and other free radical scavenging activities. From IC50 values it was deduced that antioxidant compounds were located in the ethyl acetate soluble fraction. Thus Indian propolis was shown to act as a natural antioxidant; these properties may make it useful for pharmaceutical industries and as a food supplement.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"11 1","pages":"110-120"},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82654719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The benefits of bee honey in human health have long been recognized. Honey possesses antioxidant, chemopreventive, anti-atherogenic, immunoregulatory, antimicrobial and wound healing properties, however, the effects of honey on immune functions and its antitumour activity are not well characterised. This review explores the immunomodulatory and antitumour activity of bee honey in experimental studies and clinical studies and provides a broader perspective on the use of honey in the cancer setting. Evidence to support the use of honey in the treatment of radiation-induced mucositis, radiotherapy-induced and chemotherapy-induced skin reactions, the oral cavity and external surgical wounds is presented.
{"title":"Bee honey and cancer","authors":"N. Oršolić","doi":"10.3896/IBRA.4.01.4.01","DOIUrl":"https://doi.org/10.3896/IBRA.4.01.4.01","url":null,"abstract":"The benefits of bee honey in human health have long been recognized. Honey possesses antioxidant, chemopreventive, anti-atherogenic, immunoregulatory, antimicrobial and wound healing properties, however, the effects of honey on immune functions and its antitumour activity are not well characterised. This review explores the immunomodulatory and antitumour activity of bee honey in experimental studies and clinical studies and provides a broader perspective on the use of honey in the cancer setting. Evidence to support the use of honey in the treatment of radiation-induced mucositis, radiotherapy-induced and chemotherapy-induced skin reactions, the oral cavity and external surgical wounds is presented.","PeriodicalId":14866,"journal":{"name":"Journal of Apiproduct and Apimedical Science","volume":"35 1","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87158441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：