Pub Date : 2019-01-01DOI: 10.4172/1948-5956.1000577
D. Kartini, S. S. Panigoro, M. Ramli, R. Setiabudy, A. Taher
It is common for patient undergoing cancer treatment to consume any kind of supplement in order to enhance treatment efficacy or minimize side effects. There are many supplementations available out there including antioxidant which is used by approximately 22-83% cancer patients [1-3]. This group of antioxidant includes N-acetylcysteine, glutathione, vitamin A, vitamin C, vitamin E, beta carotene, melatonin, and many others. The one which has been explored by many researchers is melatonin (MLT).
{"title":"The Role of Melatonin in Improving Clinical Responses of Chemotherapy in Solid Cancer Patients: A Systematic Review","authors":"D. Kartini, S. S. Panigoro, M. Ramli, R. Setiabudy, A. Taher","doi":"10.4172/1948-5956.1000577","DOIUrl":"https://doi.org/10.4172/1948-5956.1000577","url":null,"abstract":"It is common for patient undergoing cancer treatment to consume any kind of supplement in order to enhance treatment efficacy or minimize side effects. There are many supplementations available out there including antioxidant which is used by approximately 22-83% cancer patients [1-3]. This group of antioxidant includes N-acetylcysteine, glutathione, vitamin A, vitamin C, vitamin E, beta carotene, melatonin, and many others. The one which has been explored by many researchers is melatonin (MLT).","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"6 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83763841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-11DOI: 10.4172/1948-5956-C11-152
pHuihuang Yanp
{"title":"Identification of epigenetic signatures associated with T-cell Prolymphocytic Leukemia","authors":"pHuihuang Yanp","doi":"10.4172/1948-5956-C11-152","DOIUrl":"https://doi.org/10.4172/1948-5956-C11-152","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72931014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-03DOI: 10.4172/1948-5956-C9-146
pShiawYih Linp
{"title":"Signature-guided approaches for targeting DNA damage response defects in cancer","authors":"pShiawYih Linp","doi":"10.4172/1948-5956-C9-146","DOIUrl":"https://doi.org/10.4172/1948-5956-C9-146","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72810696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-13DOI: 10.4172/1948-5956-C1-158
pColin Paul Spearsp
{"title":"Standardized approach for comparison of therapeutic, mutagenic and environmental alkylating agents in protic media","authors":"pColin Paul Spearsp","doi":"10.4172/1948-5956-C1-158","DOIUrl":"https://doi.org/10.4172/1948-5956-C1-158","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84716064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-13DOI: 10.4172/1948-5956-C8-143
Shinji Osada
{"title":"Strategy for colorectal cancer liver metastases","authors":"Shinji Osada","doi":"10.4172/1948-5956-C8-143","DOIUrl":"https://doi.org/10.4172/1948-5956-C8-143","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"220 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89124761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-08-09DOI: 10.4172/1948-5956-c6-139
pAppiah Aaron Oseip
{"title":"Expanding the possibilities of women’s health care","authors":"pAppiah Aaron Oseip","doi":"10.4172/1948-5956-c6-139","DOIUrl":"https://doi.org/10.4172/1948-5956-c6-139","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86009542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-27DOI: 10.4172/1948-5956-c5-134
S. Limbachiya
{"title":"Optimizing swallowing outcomes and management of dysphagia in head and neck cancer","authors":"S. Limbachiya","doi":"10.4172/1948-5956-c5-134","DOIUrl":"https://doi.org/10.4172/1948-5956-c5-134","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80499138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-27DOI: 10.4172/1948-5956-C5-135
D. Poprawski
{"title":"Colorectal cancer down staging in geriatric oncology","authors":"D. Poprawski","doi":"10.4172/1948-5956-C5-135","DOIUrl":"https://doi.org/10.4172/1948-5956-C5-135","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73502832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-22DOI: 10.4172/1948-5956.1000536
T. Kirita, N. Yamakawa, N. Ueda, T. Yagyuu
Tumor budding, defined as the presence of single cancer cells or small clusters of fewer than five cells at the tumor invasive front, has been reported to be an independent prognostic factor for several cancers together with margin status, depth of invasion, lymph vascular invasion, and lymph node metastasis. Distant metastasis and poor prognosis were significantly more common in the higher budding group. In this short review, we focused on the studies related to tumor budding in several cancers including oral squamous cell carcinoma(OSCC) and showed the association among the intensity of tumor budding, risk of lymph node metastasis, and poor prognosis in OSCC is strongly supported by many studies. Moreover, arguments for the assessment of tumor budding, scoring system, stains to mark budding, specimens, and the association with epithelial mesenchymal transition (EMT) are also discussed.
{"title":"Tumor Budding as a Useful Prognostic Indicator in Early Oral Squamous Cell Carcinoma","authors":"T. Kirita, N. Yamakawa, N. Ueda, T. Yagyuu","doi":"10.4172/1948-5956.1000536","DOIUrl":"https://doi.org/10.4172/1948-5956.1000536","url":null,"abstract":"Tumor budding, defined as the presence of single cancer cells or small clusters of fewer than five cells at the tumor invasive front, has been reported to be an independent prognostic factor for several cancers together with margin status, depth of invasion, lymph vascular invasion, and lymph node metastasis. Distant metastasis and poor prognosis were significantly more common in the higher budding group. In this short review, we focused on the studies related to tumor budding in several cancers including oral squamous cell carcinoma(OSCC) and showed the association among the intensity of tumor budding, risk of lymph node metastasis, and poor prognosis in OSCC is strongly supported by many studies. Moreover, arguments for the assessment of tumor budding, scoring system, stains to mark budding, specimens, and the association with epithelial mesenchymal transition (EMT) are also discussed.","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"42 1","pages":"162-167"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80392719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-20DOI: 10.4172/1948-5956-c11-153
Bing Li
{"title":"Circulating adipose fatty acid binding protein is a new link underlying obesity-associated breast/ mammary tumor development","authors":"Bing Li","doi":"10.4172/1948-5956-c11-153","DOIUrl":"https://doi.org/10.4172/1948-5956-c11-153","url":null,"abstract":"","PeriodicalId":15170,"journal":{"name":"Journal of Cancer Science & Therapy","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76302486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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