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Canadian Association of Cardiovascular Prevention and Rehabilitation (CACPR) 2025 Spring Conference Abstracts. 加拿大心血管预防和康复协会(CACPR) 2025年春季会议摘要。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-06-26 DOI: 10.1097/HCR.0000000000000980
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引用次数: 0
Effect of Masking Secondary to the COVID-19 Pandemic on Pulmonary Rehabilitation Outcomes. COVID-19大流行继发掩蔽对肺部康复结局的影响
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-06-26 DOI: 10.1097/HCR.0000000000000949
Frederick Lu, Arlene Gaw, Jacqueline Pierce, Julianne DeAngelis, James Simmons, Wen-Chih Wu
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引用次数: 0
Differences in Cardiac Rehabilitation Enrollment by Referral Setting. 转诊设置在心脏康复登记中的差异。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-05-23 DOI: 10.1097/HCR.0000000000000947
Kevin Chen, Julianne DeAngelis, Dana Antinozzi, Julia Berkowitz, Joanne Kerwin, Wen-Chih Wu

Purpose: National guidelines have focused on increasing early referrals to cardiac rehabilitation (CR) before hospital discharge. However, patients often have not seen their cardiologists for a CR discussion, which may affect their willingness to enroll. This study compared the odds of enrollment between inpatient, outpatient, and dual (inpatient and outpatient) referrals.

Methods: A retrospective study was conducted on 1614 patients referred to CR within a university hospital system in Rhode Island from October 1, 2021 to September 30, 2022. Rates of CR enrollment were compared across inpatient (n = 807), outpatient (n = 670), and dual (n = 137) referral settings. Multivariable regression models, including demographics and comorbidities, were used to identify predictors of enrollment.

Results: A total of 874 (54%) patients enrolled with 40% of patients with inpatient referrals enrolling compared to 70% and 60% of those with outpatient and dual referrals, respectively ( P < .005). The average time between referral to initial visit was 24.2 ± 20.0 days. Regression modeling showed that patients with outpatient (OR = 3.74: 95% CI, 2.97-4.72) and those with dual referrals (OR = 2.09: 95% CI, 1.44-3.05) had higher odds of enrolling than those with inpatient referrals. Additionally, patients >80 years had lower odds of enrolling (OR = 0.50: 95% CI, 0.36-0.71) compared to younger patients.

Conclusions: Patients with outpatient referrals and dual referrals had greater odds of CR enrollment compared to those with inpatient referrals. Older patients (age >80 years) had lower odds of enrollment compared to those aged 50 to 65 years. Studies should focus on how to strengthen the inpatient CR referral process and tailor the CR discussion to meet older patient needs.

目的:国家指南的重点是在出院前增加心脏康复(CR)的早期转诊。然而,患者通常没有见过他们的心脏病专家进行CR讨论,这可能会影响他们的报名意愿。本研究比较了住院、门诊和双重(住院和门诊)转诊的入组率。方法:对2021年10月1日至2022年9月30日在罗德岛州一所大学医院系统内转诊CR的1614例患者进行回顾性研究。比较住院患者(n = 807)、门诊患者(n = 670)和双重转诊患者(n = 137)的CR入组率。使用多变量回归模型,包括人口统计学和合并症,来确定入组的预测因素。结果:共有874例(54%)患者入组,其中住院转诊患者入组比例为40%,门诊和双重转诊患者入组比例分别为70%和60%(80岁的患者入组几率较年轻患者低(OR = 0.50: 95% CI, 0.36-0.71)。结论:门诊转诊和双重转诊的患者与住院转诊的患者相比,CR入组的几率更大。老年患者(50 ~ 80岁)的入组率低于50 ~ 65岁的患者。研究应侧重于如何加强住院CR转诊流程和调整CR讨论以满足老年患者的需求。
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引用次数: 0
Heatwaves and Heart Health: A Survey Study and Discussion on the Current Knowledge and Attitudes of Cardiac Rehabilitation Clinicians. 热浪与心脏健康:对心脏康复临床医生当前知识和态度的调查研究与探讨。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-05-23 DOI: 10.1097/HCR.0000000000000951
Georgia K Chaseling, Sarah Gauci, Matthew Hollings, Susie Cartledge, Julie Redfern, Tom Briffa, Robyn Gallagher, Adrienne O'Neil

Purpose: Heat-related cardiovascular deaths are increasingly common for people with cardiovascular disease (CVD) in the face of a warming climate. Cardiac rehabilitation clinicians are well placed to educate people with CVD about the risks of heatwaves, but little is understood about their knowledge of this issue. We conducted an Australia-wide survey to understand cardiac rehabilitation clinician knowledge and attitudes regarding the health impacts of heatwaves for people with CVD.

Methods: This online REDCap survey was distributed through the National Heart Foundation, Australian Cardiovascular Health and Rehabilitation Association, and SOLVE-CHD networks to cardiac rehabilitation clinicians across Australia. Questions were open-ended and multiple choice about the health impacts of heatwaves and available support for people with CVD. Open-ended questions were thematically coded, and all other responses were presented as percentages.

Results: Ninety-nine clinicians in 7 states/territories (70% registered nurses) completed the survey. Only 17% believed sufficient information existed on the heat-health impacts for people with CVD, and 16% thought those with CVD were aware of these negative effects. Half (51%) of the respondents were aware that medication could influence physiological responses to heat but raised concerns regarding a lack of clear hydration guidance for people taking diuretics during a heatwave. Forty-five percent of clinicians said adequate information was available regarding exercise in the heat. Electric fan use (65%) and visiting a cooling center (64%) were the most recommended cooling strategies.

Conclusions: Generating educational material and incorporating evidence-based heat management strategies into rehabilitation programs will be vital to reduce cardiovascular events during heatwaves.

目的:面对气候变暖,与热相关的心血管死亡在心血管疾病(CVD)患者中越来越常见。心脏康复临床医生可以很好地教育心血管疾病患者热浪的风险,但他们对这个问题的了解很少。我们进行了一项澳大利亚范围内的调查,以了解心脏康复临床医生对热浪对心血管疾病患者健康影响的知识和态度。方法:这项在线REDCap调查通过国家心脏基金会、澳大利亚心血管健康与康复协会和SOLVE-CHD网络分发给澳大利亚各地的心脏康复临床医生。问题是关于热浪对健康的影响和对心血管疾病患者的可用支持的开放式和多项选择。开放式问题按主题编码,所有其他回答都以百分比表示。结果:来自7个州/地区的99名临床医生(70%为注册护士)完成了调查。只有17%的人认为有足够的信息表明心血管疾病患者的热健康影响,16%的人认为心血管疾病患者意识到这些负面影响。一半(51%)的受访者意识到药物会影响对热的生理反应,但他们担心在热浪中服用利尿剂的人缺乏明确的补水指导。45%的临床医生表示,关于高温下的运动有足够的信息。使用电风扇(65%)和去制冷中心(64%)是最受推荐的制冷策略。结论:制作教育材料并将循证热管理策略纳入康复计划对于减少热浪期间的心血管事件至关重要。
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引用次数: 0
Cost-Effectiveness of Case Management and Financial Incentives to Increase Participation in Cardiac Rehabilitation. 增加心脏康复参与的病例管理和财政激励的成本效益。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.1097/HCR.0000000000000952
Donald S Shepard, Jiaye Shen, Blair K Yant, Deborah E Denkmann, Patrick D Savage, Robin K Collier, Brian R Katz, Philip A Ades, Diann E Gaalema

Purpose: As cardiac rehabilitation (CR) is highly effective, cost-effective, and professionally recommended, policymakers seek to increase utilization. Here we applied results from a randomized trial of case management (CM) and financial incentives (FI), paid as retail gift cards, separately and combined. We modeled their impact and cost-effectiveness compared to usual care (UC) in increasing quality-adjusted life years (QALYs).

Methods: Staff time logs, FI payouts, and CR attendance records generated short-term data. We derived the lifetime QALYs and cost-effectiveness (in 2022 US dollars) from a 2024 cost-effectiveness study of CR calibrated from an observational cohort of 601 099 CR-eligible Medicare beneficiaries. That cohort study controlled for confounding using instrumental variables (IV) and propensity-based (PB) matching.

Results: The FI alone and CM + FI combined interventions increased CR sessions significantly. Additional CR sessions per participant averaged 7.04 (95% CI, 0.93-13.15) with FI and 13.63 (95% CI, 7.86-19.41) with CM + FI. The CM alone intervention did not increase sessions significantly (mean = 1.53: 95% CI, -4.23 to 7.56). The CM + FI intervention generated the most lifetime QALYs, 0.733 (IV) and 1.100 (PB), and displayed a powerful synergy between CM and FI. Under CM + FI, the cost of financial payouts averaged $1088 (range $0-$1966), and total intervention costs averaged $2388. The lifetime cost-effectiveness of CM + FI was 29.966 (95% CI, 29.636-30.296, IV) or 29.257 (95% CI, 28.935-29.579 PB) QALYs/$million. Both values substantially surpassed the average threshold of the United States health care system (10.421 QALYs/$million).

Conclusions: The CM + FI intervention proved highly effective and more than twice as cost-effective as the average of all health interventions in the United States. Thus, CM + FI, combined with other effective interventions such as automatic referral and home-based CR, merit widespread implementation and funding.

目的:由于心脏康复(CR)是一种高效、经济、专业推荐的方法,决策者寻求提高其利用率。在这里,我们应用了案例管理(CM)和财务激励(FI)随机试验的结果,分别以零售礼品卡的形式支付,并将其合并。与常规护理(UC)相比,我们模拟了它们在增加质量调整生命年(QALYs)方面的影响和成本效益。方法:员工工时日志、FI支出和CR考勤记录生成短期数据。我们从2024年的一项CR成本效益研究中得出终身质量年和成本效益(以2022年美元计算),该研究对601 099名符合CR条件的医疗保险受益人进行了观察性队列校准。该队列研究使用工具变量(IV)和基于倾向(PB)匹配控制混淆。结果:FI单独和CM + FI联合干预显著增加了CR时间。每个参与者额外的CR疗程平均为FI组7.04次(95% CI, 0.93-13.15), CM + FI组13.63次(95% CI, 7.86-19.41)。单独CM干预并没有显著增加疗程(平均值= 1.53:95% CI, -4.23至7.56)。CM + FI干预产生了最多的生命周期qaly,分别为0.733 (IV)和1.100 (PB),显示出CM和FI之间强大的协同作用。在CM + FI下,财务支出成本平均为1088美元(范围为0- 1966美元),总干预成本平均为2388美元。CM + FI的终生成本-效果为29.966 (95% CI, 29.636-30.296, IV)或29.257 (95% CI, 28.935-29.579 PB) QALYs/$million。这两个值都大大超过了美国医疗保健系统的平均门槛(10421个质量年/百万美元)。结论:CM + FI干预被证明是非常有效的,其成本效益是美国所有健康干预平均成本的两倍以上。因此,CM + FI,结合其他有效的干预措施,如自动转诊和基于家庭的CR,值得广泛实施和资助。
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引用次数: 0
The Basic Science of Behavior Change in COPD: Testing Self-Determination Theory to Support Home-Based Rehabilitation With Health Coaching. COPD患者行为改变的基础科学:测试自我决定理论以支持健康指导的家庭康复。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-06-26 DOI: 10.1097/HCR.0000000000000957
Maria Benzo, Minji Lee, Matthew M Clark, Roberto Benzo

Purpose: Home-based pulmonary rehabilitation (HBPR) with health coaching (HC) in people with chronic obstructive pulmonary disease (COPD) has been reported to produce behavior change by improving accelerometry-measured physical activity level and quality of life (QoL). However, a theoretical framework supporting the observed behavior change has not been tested in people with COPD. Therefore, the purpose of this secondary analysis was to examine the mechanism by which HBPR with HC improved physical and emotional QoL, by testing a theoretical framework that may support the positive effect of the intervention. The hypothesis was that the Self-Determination Theory (SDT) supports the behavior change observed after the 12-week HBPR with HC in patients with moderate to very severe COPD. This theory posits that by supporting the individual's experience of autonomy, competence, and relatedness can foster the most volitional and high-quality forms of motivation and engagement for a behavior change.

Methods: Structural Equation Models (Path Analysis) tested the underlying assumption that competence, autonomy, and relatedness were the factors associated with improvement in the physical and emotional QoL post-intervention.

Results: The path models supported the effect HBPR with HC on physical and emotional QoL through a direct effect on competence and relatedness ( P <.01) and an indirect effect through autonomy via competence and relatedness.

Conclusions: The effect of HBPR with HC in patients with COPD is mechanistically supported by SDT. Addressing competence, relatedness, and autonomy during the pulmonary rehabilitation process may impact physical and emotional QoL, which is of utmost importance to these patients.

目的:据报道,慢性阻塞性肺疾病(COPD)患者的家庭肺康复(HBPR)与健康指导(HC)可以通过改善加速度计测量的身体活动水平和生活质量(QoL)来产生行为改变。然而,支持观察到的行为改变的理论框架尚未在COPD患者中进行测试。因此,本二次分析的目的是通过测试一个可能支持干预积极作用的理论框架,来检验HBPR与HC改善身体和情绪生活质量的机制。假设是自我决定理论(SDT)支持在中度至极重度COPD患者进行12周HBPR合并HC后观察到的行为改变。该理论认为,通过支持个体的自主、能力和关系体验,可以培养出最具意志和高质量的动机和参与形式,以促进行为改变。方法:结构方程模型(通径分析)检验了能力、自主性和相关性是干预后身体和情绪生活质量改善的相关因素的基本假设。结果:路径模型通过对能力和相关性的直接影响,支持HBPR + HC对COPD患者身体和情绪生活质量的影响(P)结论:SDT支持HBPR + HC对COPD患者的作用。在肺康复过程中处理能力、相关性和自主性可能会影响身体和情绪的生活质量,这对这些患者至关重要。
{"title":"The Basic Science of Behavior Change in COPD: Testing Self-Determination Theory to Support Home-Based Rehabilitation With Health Coaching.","authors":"Maria Benzo, Minji Lee, Matthew M Clark, Roberto Benzo","doi":"10.1097/HCR.0000000000000957","DOIUrl":"10.1097/HCR.0000000000000957","url":null,"abstract":"<p><strong>Purpose: </strong>Home-based pulmonary rehabilitation (HBPR) with health coaching (HC) in people with chronic obstructive pulmonary disease (COPD) has been reported to produce behavior change by improving accelerometry-measured physical activity level and quality of life (QoL). However, a theoretical framework supporting the observed behavior change has not been tested in people with COPD. Therefore, the purpose of this secondary analysis was to examine the mechanism by which HBPR with HC improved physical and emotional QoL, by testing a theoretical framework that may support the positive effect of the intervention. The hypothesis was that the Self-Determination Theory (SDT) supports the behavior change observed after the 12-week HBPR with HC in patients with moderate to very severe COPD. This theory posits that by supporting the individual's experience of autonomy, competence, and relatedness can foster the most volitional and high-quality forms of motivation and engagement for a behavior change.</p><p><strong>Methods: </strong>Structural Equation Models (Path Analysis) tested the underlying assumption that competence, autonomy, and relatedness were the factors associated with improvement in the physical and emotional QoL post-intervention.</p><p><strong>Results: </strong>The path models supported the effect HBPR with HC on physical and emotional QoL through a direct effect on competence and relatedness ( P <.01) and an indirect effect through autonomy via competence and relatedness.</p><p><strong>Conclusions: </strong>The effect of HBPR with HC in patients with COPD is mechanistically supported by SDT. Addressing competence, relatedness, and autonomy during the pulmonary rehabilitation process may impact physical and emotional QoL, which is of utmost importance to these patients.</p>","PeriodicalId":15192,"journal":{"name":"Journal of Cardiopulmonary Rehabilitation and Prevention","volume":" ","pages":"286-293"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attacks or Mild Non-Disabling Strokes: A Feasibility and Effectiveness Randomized Controlled Trial. 短暂性脑缺血发作或轻度非致残性中风后心脏康复二级预防的可行性和有效性随机对照试验
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-06-13 DOI: 10.1097/HCR.0000000000000955
Melissa Majoni, Saverio Stranges, Richard K T Chan, Neville Suskin, Peter L Prior
{"title":"Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attacks or Mild Non-Disabling Strokes: A Feasibility and Effectiveness Randomized Controlled Trial.","authors":"Melissa Majoni, Saverio Stranges, Richard K T Chan, Neville Suskin, Peter L Prior","doi":"10.1097/HCR.0000000000000955","DOIUrl":"10.1097/HCR.0000000000000955","url":null,"abstract":"","PeriodicalId":15192,"journal":{"name":"Journal of Cardiopulmonary Rehabilitation and Prevention","volume":" ","pages":"300-302"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When the Treatment Needs a Home: The Application of Exercise Interventions in Long COVID. 当治疗需要一个家:运动干预在长期COVID中的应用。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-07-01 Epub Date: 2025-06-26 DOI: 10.1097/HCR.0000000000000981
Katherine E Menson, Diann E Gaalema
{"title":"When the Treatment Needs a Home: The Application of Exercise Interventions in Long COVID.","authors":"Katherine E Menson, Diann E Gaalema","doi":"10.1097/HCR.0000000000000981","DOIUrl":"10.1097/HCR.0000000000000981","url":null,"abstract":"","PeriodicalId":15192,"journal":{"name":"Journal of Cardiopulmonary Rehabilitation and Prevention","volume":"45 4","pages":"233-235"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Home-Based Cardiac Rehabilitation on Physical Function, Outcomes, and Costs. 家庭心脏康复对身体功能、结果和费用的影响。
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-05-01 Epub Date: 2025-04-02 DOI: 10.1097/HCR.0000000000000931
Jonathan Myers, Karen Owoc, Holly Fonda, Khin Chan, Thant Zin Oo, Shriram Nallamshetty, Patricia Nguyen

Purpose: Cardiac rehabilitation (CR) improves health outcomes in patients with cardiovascular disease (CVD), but referral, participation, and completion rates are low. Home-based CR (HBCR) is a proposed solution, but studies on its efficacy are limited. We report our experience from a Veterans Affairs HBCR program on physical function, costs, and outcomes overlapping with the coronavirus disease-2019 (COVID-19) pandemic.

Methods: A 12-week HBCR program included case-managed individualized exercise and risk management. Six functional tests were conducted remotely, safety was monitored, and quality of life and costs were quantified. A composite outcome (death, myocardial infarction, stroke, and cardiac-related hospitalization) was compared between 70 HBCR participants, 131 patients referred to Community Care, and 71 patients undergoing usual care (no CR) over a mean follow-up of 2.5 ± 0.90 years.

Results: Among HBCR participants, there were significant improvements in right and left leg balance (145 and 56%, respectively, P < .001), 30-second chair stand (47%, P < .001), 2-minute step performance (41%, P < .001), right and left 30-second arm curl (31 and 30%, respectively, P < .001), 50-foot walk test (20%, P = .002), 8-foot up and go test (28%, P < .001), and steps/day (82%, P < .001). Composite events were lower among patients in the HBCR group versus those referred to Community Care ( P = .002). Health care costs were significantly lower among patients in the HBCR group compared to those in Community Care ($2101 vs $3289/subject, P < .001).

Conclusions: A HBCR program that included a broad spectrum of patients with CVD and multiple co-morbidities, performed largely during the COVID-19 pandemic, resulted in significant functional and outcome benefits and reduced costs.

目的:心脏康复(CR)可改善心血管疾病(CVD)患者的健康结局,但转诊、参与和完成率较低。基于家庭的CR (HBCR)是一种被提出的解决方案,但对其有效性的研究有限。我们报告了退伍军人事务HBCR项目在与2019冠状病毒病(COVID-19)大流行重叠的身体功能、成本和结果方面的经验。方法:为期12周的HBCR项目包括个案管理的个体化锻炼和风险管理。远程进行了六项功能测试,监测了安全性,并量化了生活质量和成本。在平均随访2.5±0.90年期间,比较了70名HBCR参与者、131名社区护理患者和71名接受常规护理(无CR)的患者的综合结果(死亡、心肌梗死、卒中和心脏相关住院)。结果:在HBCR参与者中,右腿和左腿平衡有显著改善(分别为145%和56%)。结论:HBCR项目包括广泛的心血管疾病和多种合合症患者,主要在COVID-19大流行期间进行,产生了显着的功能和预后益处,并降低了成本。
{"title":"Impact of Home-Based Cardiac Rehabilitation on Physical Function, Outcomes, and Costs.","authors":"Jonathan Myers, Karen Owoc, Holly Fonda, Khin Chan, Thant Zin Oo, Shriram Nallamshetty, Patricia Nguyen","doi":"10.1097/HCR.0000000000000931","DOIUrl":"10.1097/HCR.0000000000000931","url":null,"abstract":"<p><strong>Purpose: </strong>Cardiac rehabilitation (CR) improves health outcomes in patients with cardiovascular disease (CVD), but referral, participation, and completion rates are low. Home-based CR (HBCR) is a proposed solution, but studies on its efficacy are limited. We report our experience from a Veterans Affairs HBCR program on physical function, costs, and outcomes overlapping with the coronavirus disease-2019 (COVID-19) pandemic.</p><p><strong>Methods: </strong>A 12-week HBCR program included case-managed individualized exercise and risk management. Six functional tests were conducted remotely, safety was monitored, and quality of life and costs were quantified. A composite outcome (death, myocardial infarction, stroke, and cardiac-related hospitalization) was compared between 70 HBCR participants, 131 patients referred to Community Care, and 71 patients undergoing usual care (no CR) over a mean follow-up of 2.5 ± 0.90 years.</p><p><strong>Results: </strong>Among HBCR participants, there were significant improvements in right and left leg balance (145 and 56%, respectively, P < .001), 30-second chair stand (47%, P < .001), 2-minute step performance (41%, P < .001), right and left 30-second arm curl (31 and 30%, respectively, P < .001), 50-foot walk test (20%, P = .002), 8-foot up and go test (28%, P < .001), and steps/day (82%, P < .001). Composite events were lower among patients in the HBCR group versus those referred to Community Care ( P = .002). Health care costs were significantly lower among patients in the HBCR group compared to those in Community Care ($2101 vs $3289/subject, P < .001).</p><p><strong>Conclusions: </strong>A HBCR program that included a broad spectrum of patients with CVD and multiple co-morbidities, performed largely during the COVID-19 pandemic, resulted in significant functional and outcome benefits and reduced costs.</p>","PeriodicalId":15192,"journal":{"name":"Journal of Cardiopulmonary Rehabilitation and Prevention","volume":" ","pages":"200-206"},"PeriodicalIF":3.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined Physical Exercise in Pulmonary Rehabilitation Does Not Alter Endothelial Function and Vascular Structure in Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial. 肺康复中的联合体育锻炼不会改变慢性阻塞性肺病患者的内皮功能和血管结构:随机临床试验
IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-05-01 Epub Date: 2025-04-02 DOI: 10.1097/HCR.0000000000000940
Talmir Nolasco, Renata Figueiredo, Priscila Zanella, Francini Porcher, Ricardo Gass, Melina Hauck, Marli Knorst

Purpose: The aim of this study was to analyze the effect of exercise on endothelial function and other cardiovascular risk factors in patients with chronic obstructive pulmonary disease (COPD).

Methods: Forty patients were randomized to an 8-week pulmonary rehabilitation (PR) program or usual care. Symptoms, exercise capacity, and quality of life were measured at baseline and after intervention or observation. Flow-mediated brachial artery dilation (FMD), ankle-brachial index, intermittent claudication questionnaire, cardiovascular risk score, blood pressure, daily steps count, glucose, lipids, and C-reactive protein were evaluated before and after intervention.

Results: Participants had a mean age of 64.2 ± 6.7 years in the PR group and 62.2 ± 8.0 years in the usual care group. The forced expiratory volume in the first second was 45.5 ± 15.4% predicted in the PR group and 48.1 ± 24.3% predicted in the usual care group. Attending PR was associated with reduced symptoms, improved exercise capacity and quality of life in patients with COPD ( P < .005 for all). Endothelial function did not improve after PR (FMD% at baseline 9.38 ± 4.40 vs 9.67 ± 6.56 post PR; P = .87), and there was no difference between the 2 groups ( P = .61). However, exercise reduced C-reactive protein, triglycerides, and glucose and improved cardiovascular risk score, systemic blood pressure, and ankle-brachial index ( P < .005 for all).

Conclusions: Pulmonary rehabilitation elicited improvement in symptoms, exercise capacity, quality of life, and parameters related to cardiorespiratory fitness. The endothelial function measured by FMD did not change with exercise. However, other cardiovascular risk factors such as blood markers, systemic blood pressure, and lower limb blood flow improved after PR.

目的:本研究的目的是分析运动对慢性阻塞性肺疾病(COPD)患者内皮功能及其他心血管危险因素的影响。方法:40例患者随机分为8周肺康复(PR)组和常规护理组。在基线和干预或观察后测量症状、运动能力和生活质量。在干预前后评估血流介导的肱动脉扩张(FMD)、踝关节-肱指数、间歇性跛行问卷、心血管风险评分、血压、每日步数、血糖、血脂和c反应蛋白。结果:PR组平均年龄64.2±6.7岁,常规护理组平均年龄62.2±8.0岁。第一秒用力呼气量PR组预测为45.5±15.4%,常规护理组预测为48.1±24.3%。参加PR与COPD患者症状减轻、运动能力改善和生活质量相关(P结论:肺康复可改善症状、运动能力、生活质量和心肺健康相关参数。FMD测量的内皮功能不随运动而改变。然而,其他心血管危险因素,如血液标志物、全身血压和下肢血流在PR后得到改善。
{"title":"Combined Physical Exercise in Pulmonary Rehabilitation Does Not Alter Endothelial Function and Vascular Structure in Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial.","authors":"Talmir Nolasco, Renata Figueiredo, Priscila Zanella, Francini Porcher, Ricardo Gass, Melina Hauck, Marli Knorst","doi":"10.1097/HCR.0000000000000940","DOIUrl":"10.1097/HCR.0000000000000940","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to analyze the effect of exercise on endothelial function and other cardiovascular risk factors in patients with chronic obstructive pulmonary disease (COPD).</p><p><strong>Methods: </strong>Forty patients were randomized to an 8-week pulmonary rehabilitation (PR) program or usual care. Symptoms, exercise capacity, and quality of life were measured at baseline and after intervention or observation. Flow-mediated brachial artery dilation (FMD), ankle-brachial index, intermittent claudication questionnaire, cardiovascular risk score, blood pressure, daily steps count, glucose, lipids, and C-reactive protein were evaluated before and after intervention.</p><p><strong>Results: </strong>Participants had a mean age of 64.2 ± 6.7 years in the PR group and 62.2 ± 8.0 years in the usual care group. The forced expiratory volume in the first second was 45.5 ± 15.4% predicted in the PR group and 48.1 ± 24.3% predicted in the usual care group. Attending PR was associated with reduced symptoms, improved exercise capacity and quality of life in patients with COPD ( P < .005 for all). Endothelial function did not improve after PR (FMD% at baseline 9.38 ± 4.40 vs 9.67 ± 6.56 post PR; P = .87), and there was no difference between the 2 groups ( P = .61). However, exercise reduced C-reactive protein, triglycerides, and glucose and improved cardiovascular risk score, systemic blood pressure, and ankle-brachial index ( P < .005 for all).</p><p><strong>Conclusions: </strong>Pulmonary rehabilitation elicited improvement in symptoms, exercise capacity, quality of life, and parameters related to cardiorespiratory fitness. The endothelial function measured by FMD did not change with exercise. However, other cardiovascular risk factors such as blood markers, systemic blood pressure, and lower limb blood flow improved after PR.</p>","PeriodicalId":15192,"journal":{"name":"Journal of Cardiopulmonary Rehabilitation and Prevention","volume":" ","pages":"215-223"},"PeriodicalIF":3.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Cardiopulmonary Rehabilitation and Prevention
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