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Positive Childhood Experiences and the Indirect Relationship With Improved Emotion Regulation in Adults With ADHD Through Social Support. 积极的童年经历与通过社会支持改善多动症成人情绪调节的间接关系。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-11-01 Epub Date: 2024-06-24 DOI: 10.1177/10870547241261826
Catherine T Lowe, Alexandra C Bath, Brandy L Callahan, Emma A Climie

Objective: To identify direct and indirect associations between PCEs and social support to emotion regulation outcomes in adults with ADHD.

Method: Adults with ADHD (n = 81) reported PCEs, current social support, and emotion regulation. Conditional effects modeling examined the direct and indirect relationships between PCEs and emotion dysregulation through social support.

Results: Higher PCEs were indirectly related to improved emotion regulation through increased social support generally (β = -.70, 95% CI [-1.32, -0.17], and specifically through belonging (β = -.43, 95% CI [ -0.87, -0.05], self-esteem (β = -.61, 95% CI [-1.08, -0.27], and tangible social support (β = -.50, 95% CI [-1.07, -0.02].

Conclusions: PCEs may protect emotion regulation in adults with ADHD through social support, possibly through facilitating social connections, increasing access to social support, and sustaining emotion regulation strategies.

目的确定PCE和社会支持与ADHD成人情绪调节结果之间的直接和间接联系:方法:患有多动症的成年人(n = 81)报告 PCEs、当前社会支持和情绪调节。条件效应模型检验了 PCEs 与通过社会支持调节情绪失调之间的直接和间接关系:结果:较高的 PCEs 与通过增加社会支持改善情绪调节有间接关系(β = -.70, 95% CI [-1.32, -0.17]),特别是通过归属感(β = -.43, 95% CI [ -0.87, -0.05])、自尊(β = -.61, 95% CI [-1.08, -0.27])和有形社会支持(β = -.50, 95% CI [-1.07, -0.02]):PCE可通过社会支持保护成人多动症患者的情绪调节能力,可能是通过促进社会联系、增加获得社会支持的机会和维持情绪调节策略。
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引用次数: 0
Concussion Characteristics in Adults With ADHD Seen in a Specialty Concussion Clinic. 在脑震荡专科门诊就诊的多动症成人的脑震荡特征。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-25 DOI: 10.1177/10870547241292465
Rachel S Johnson, Hillary E Swann-Thomsen, Naida Dillion, Elyse A C Palumbo, Kristi Pardue, Hilary Flint, Kurt J Nilsson

Background: Concussions are a prevalent health concern, affecting millions of individuals in the United States yearly. Concussion symptomology overlaps with other conditions making diagnosis and management particularly challenging, particularly among individuals with ADHD. ADHD is a neurodevelopmental disorder that affects a significant portion of the adult population.

Objective: To enhance our understanding of symptom resolution and identify factors that could influence concussion care management, the purpose of the current study was to examine the recovery trajectory of adults diagnosed with both ADHD and concussion compared to the trajectory of adults who have experienced a concussion but do not have an ADHD diagnosis.

Methods: The study included a retrospective chart review of patients treated for concussion at a concussion specialty clinic.

Results: The findings of the study revealed no significant differences in history of concussion or recovery time between patients with and without ADHD. It was observed that patients with ADHD had a higher prevalence of anxiety, depression, and other mental health conditions.

Conclusions: The findings of the current study underscore the need for additional research to guide the care of patients diagnosed with both ADHD and concussion.

背景:脑震荡是一个普遍存在的健康问题,每年影响着美国数百万人。脑震荡的症状与其他疾病重叠,使得诊断和管理特别具有挑战性,尤其是在多动症患者中。多动症是一种神经发育障碍,影响着相当一部分成年人:为了加深我们对症状缓解情况的了解,并确定可能影响脑震荡护理管理的因素,本研究旨在对同时被诊断出患有多动症和脑震荡的成年人的康复轨迹与经历过脑震荡但未被诊断出患有多动症的成年人的康复轨迹进行比较:研究包括对在脑震荡专科门诊接受治疗的脑震荡患者进行回顾性病历审查:研究结果显示,有多动症和没有多动症的患者在脑震荡病史或康复时间上没有明显差异。据观察,患有多动症的患者患有焦虑症、抑郁症和其他精神疾病的比例较高:目前的研究结果表明,有必要开展更多的研究,以指导对同时被诊断为多动症和脑震荡患者的治疗。
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引用次数: 0
A Randomized Controlled Trial of the Effects of Organizational Skills Training on Children With Attention Deficit Hyperactivity Disorder in China. 组织能力培训对中国注意力缺陷多动障碍儿童影响的随机对照试验》。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-21 DOI: 10.1177/10870547241289848
Xin-Xin Huang, Li-Zhen Zheng, Qin-Fang Qian, Yan Huang, Yan-Xia Wang, Ping Ou

Background: In addition to attention and hyperactivity problems, children with attention deficit hyperactivity disorder (ADHD) have poorer organizational skills needed to manage time and materials. This study examines the improvement of organizational skills in children with ADHD by studying organizational skills training (OST).

Methods: This was a prospective, randomized controlled trial. Between September 2023 and January 2024, 70 children with a diagnosis of ADHD and at least one domain of executive dysfunction (EF) were divided into two groups. The conventional group was treated with medication, biofeedback, and behavioral interventions based on the children's actual condition. The OST group received OST in addition to the conventional group.

Results: The mean age of the children was 8.33 ± 1.62 years. A total of 66 children completed the intervention and follow-up, 32 in the conventional group and 34 in the OST group. There were no differences between the two groups of children in terms of their preintervention scores on the BRIEF, SNAP-IV, or IVA-CPT. Postintervention scores on the behavioral scales decreased (p < .05), and IVA-CPT scores increased (p < .05) in both groups compared with those in the preintervention period. The OST group had a lower BRIEF (p = .019) and SNAP-IV Attention deficit subscale (p = .046) and a higher IVA-CPT Attention deficit Index (p = .032) than the conventional group after the intervention. The percentage of children with a normal BRIEF total score in the OST group was 79.41% (27/34) after the intervention, which was greater than the 37.50% (12/32) in the conventional group (p = .001). Compared with the OST group, children in the conventional group were at greater risk of having BRIEF scores that remained abnormal after the intervention. Analysis of covariance revealed a statistically significant effect of group (p = .008), preintervention BRIEF (p < .001), and participation score (p = .036) on postintervention BRIEF.

Conclusion: OST can further improve organizational skills in daily life in children with ADHD while improving core symptoms of attention deficit in addition to conventional treatment. The effect of OST on BRIEF is also influenced by the child's BRIEF status at the baseline level and the level of cooperation during the intervention.

Trial registration: The randomized controlled trial registration number was ChiCTR2300075744.

背景:患有注意力缺陷多动障碍(ADHD)的儿童除了注意力和多动问题外,管理时间和材料所需的组织能力也较差。本研究通过组织能力训练(OST)来探讨如何提高多动症儿童的组织能力:这是一项前瞻性随机对照试验。2023 年 9 月至 2024 年 1 月期间,70 名被诊断为多动症且至少有一个执行功能障碍(EF)的儿童被分为两组。常规组根据儿童的实际情况接受药物、生物反馈和行为干预治疗。OST组在常规组的基础上接受OST治疗:儿童的平均年龄为(8.33 ± 1.62)岁。共有 66 名儿童完成了干预和随访,其中常规组 32 名,OST 组 34 名。两组儿童在干预前的 BRIEF、SNAP-IV 或 IVA-CPT 评分上没有差异。干预后,行为量表得分下降(p p = .019),SNAP-IV 注意力缺陷分量表得分下降(p = .046),IVA-CPT 注意力缺陷指数(p = .032)高于常规组。干预后,OST 组 BRIEF 总分正常的儿童比例为 79.41%(27/34),高于常规组的 37.50%(12/32)(p = .001)。与 OST 组相比,常规组儿童在干预后出现 BRIEF 评分异常的风险更大。协方差分析显示,组别(p = .008)、干预前 BRIEF(p p = .036)对干预后 BRIEF 的影响具有统计学意义:结论:在常规治疗的基础上,OST 可以进一步提高多动症儿童在日常生活中的组织能力,同时改善注意力缺陷的核心症状。OST对BRIEF的影响还受到儿童基线水平的BRIEF状况和干预期间合作程度的影响:随机对照试验注册号为ChiCTR2300075744。
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引用次数: 0
The Daydream Spectrum: The Role of Emotional Dysregulation, Internalized Stigma and Self-Esteem in Maladaptive Daydreaming Among Adults With ADHD, ASD, and Double Diagnosis. 白日梦光谱:多动症、自闭症和双重诊断成人的情绪失调、内化成见和自尊在适应不良的白日梦中的作用。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-21 DOI: 10.1177/10870547241290901
Anna Pyszkowska, Ari Nowacki, Julia Celban

Objective: Maladaptive daydreaming (MD) is characterized by vivid, excessive fantasy activity that becomes prioritized over other activities and may result in avoidant coping strategies. Little is known about the relationship between MD and internalized stigma in the neurodivergent sample. The current study aimed to examine emotional dysregulation, escapism and self-perception (self-esteem and internalized stigma) as potential determinants of MD in three groups: adults on the autism spectrum, with ADHD, and both diagnoses ("AuDHD"), including their neurodivergent symptoms (autistic traits, empathizing, ADHD symptoms).

Methods: A sample of 293 persons (139 with ADHD, 74 on the autism spectrum, and 80 with both diagnoses) completed self-report scales concerning ADHD symptoms, autism spectrum symptoms, empathizing, self-esteem, daydreaming as escapism, emotional dysregulation, maladaptive daydreaming, and internalized stigma. A correlation analysis was implemented. Additionally, a group comparison and quantile regression for the 25th, 50th, and 75th percentile of maladaptive daydreaming in the three groups were executed.

Results: The results showed that internalized stigma, emotional dysregulation, escapism, and self-esteem have significant associations with MD in the neurodiverse sample. The ADHD group achieved the lowest scores in emotional dysregulation, discrimination experience, and social withdrawal. The groups did not vary in MD rates, stereotype endorsement, stigma resistance, nonacceptance of emotional responses, and impulse control difficulties. The AuDHD group achieved higher results than the ASD group only in the ADHD symptoms. Quantile regression revealed differences in the predictors of maladaptive daydreaming in the three groups. ADHD symptoms and self-suppression escapism were significant predictors for the higher levels of MD in persons with singular autism or ADHD diagnosis.

Conclusion: The results showed no differences in MD rates, although there were significant variations in predictive features among the three samples. The role of internalized stigma and self-esteem was highlighted in the results as significant associates of MD prevalence. These outcomes expand the current knowledge in the context of maladaptive daydreaming, internalized stigma, self-esteem and emotional dysregulation in a neurodiverse sample and allow for proposing clinical applications and further research directions.

目的:适应不良型白日梦(MD)的特征是生动、过度的幻想活动,这种幻想活动优先于其他活动,并可能导致回避应对策略。在神经变异样本中,人们对白日梦与内化成见之间的关系知之甚少。本研究旨在探讨情绪失调、逃避现实和自我认知(自尊和内化成见)作为 MD 的潜在决定因素在自闭症谱系成人、多动症成人和同时患有两种诊断("AuDHD")的三类人群中的作用,包括他们的神经变异症状(自闭症特征、移情、多动症症状):293 人(139 人患有多动症,74 人患有自闭症谱系障碍,80 人同时患有这两种疾病)完成了有关多动症症状、自闭症谱系障碍症状、移情、自尊、逃避现实的白日梦、情绪失调、不适应性白日梦和内化耻辱的自我报告量表。研究还进行了相关分析。此外,还对三个组别中适应不良白日梦的第 25、50 和 75 百分位数进行了分组比较和量值回归:结果表明,在神经多样性样本中,内化成见、情绪失调、逃避现实和自尊与白日梦有显著关联。多动症组在情绪失调、歧视经历和社交退缩方面得分最低。各组在 MD 发生率、刻板印象认可、耻辱感抵制、不接受情绪反应和冲动控制困难方面没有差异。只有在多动症症状方面,AuDHD 组的结果高于 ASD 组。量子回归显示,三个组别在预测适应不良白日梦方面存在差异。ADHD症状和自我压抑逃避现实是单一自闭症或ADHD诊断人群白日梦水平较高的重要预测因素:结果表明,虽然三个样本的预测特征存在显著差异,但自闭症患者的自闭症发病率并无不同。结果表明,内化的耻辱感和自尊与多发性自闭症的患病率密切相关。这些结果拓展了目前对神经多样性样本中适应不良白日梦、内化成见、自尊和情绪失调的认识,并提出了临床应用和进一步研究的方向。
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引用次数: 0
Examining the Association Between Adverse Childhood Experiences and ADHD in School-Aged Children Following the COVID-19 Pandemic. 研究 COVID-19 大流行后学龄儿童的不良童年经历与多动症之间的关系。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-18 DOI: 10.1177/10870547241290673
Emma Boswell, Elizabeth Crouch, Cassie Odahowski, Peiyin Hung

Background: Adverse childhood experiences (ACEs) have long been associated with attention-deficit/hyperactive disorder (ADHD) diagnoses in children; but the data used is now over 6 years old (from 2017 to 2018). Understanding the current landscape of their prevalence and association is needed to capture evolving social, environmental, and economic conditions, and ensure interventions remain relevant to addressing current childhood trauma.

Objective: This study provides an updated analysis of the association between ACEs and ADHD using post-acute-COVID-19 pandemic data.

Participants and setting: This cross-sectional study of 10,518 children aged 5 to 17 years old derived data from the 2021 to 2022 National Health Interview Survey (NHIS).

Methods: Differences in the prevalence of number (0, 1-3, or 4+) and type of ACEs by ADHD diagnosis were evaluated using Rao-Scott chi-square tests and multivariable logistic regression. All analyses incorporate complex survey weights.

Results: In 2021 to 2022, 2,457 (23.3%) of children experienced ACEs and 1,115 (9.9%) had an ADHD diagnosis. Children with ADHD were more likely to experience every type of ACE and were more likely to have 1 to 3 or 4+ ACEs than children without ADHD. Children with 4+ ACEs had higher odds of having an ADHD diagnosis (aOR: 3.44, 95% CI [2.64, 4.49]) than children without ACEs. Male children, children with fair or poor health, and children living in rural counties were more likely to have an ADHD diagnosis, while children of color and uninsured children were less likely. We found the odds ratio of ADHD diagnosis for children with four or more ACEs, compared to those without ACEs, slightly lower than found in Brown et al., 2017's estimate of 3.97 (CI [3.29, 4.80]). These results suggest a consistent association between ACEs and ADHD when comparing pre-COVID data to our post-acute-COVID results.

Conclusions: These findings highlight the need for clinicians to consider traumatic stress in ADHD screening. Policymakers and early childhood organizations should encourage early screening and intervention for ACEs to reduce the impacts of ADHD diagnoses.

背景:长期以来,儿童不良童年经历(ACEs)一直与儿童注意力缺陷/多动障碍(ADHD)的诊断有关;但现在所使用的数据已超过 6 年(从 2017 年到 2018 年)。需要了解其流行率和相关性的现状,以掌握不断变化的社会、环境和经济条件,并确保干预措施始终与解决当前的儿童创伤问题相关:本研究利用 COVID-19 大流行后的数据,对 ACE 与多动症之间的关联进行了最新分析:这项横断面研究的 10,518 名 5 至 17 岁儿童的数据来自 2021 年至 2022 年的全国健康访谈调查(NHIS):方法:使用拉奥-斯科特卡方检验和多变量逻辑回归评估了ADHD诊断中ACE数量(0、1-3或4+)和类型的流行率差异。所有分析都采用了复杂的调查权重:在 2021 年至 2022 年期间,2,457 名儿童(23.3%)经历过 ACE,1,115 名儿童(9.9%)被诊断患有多动症。与没有多动症的儿童相比,患有多动症的儿童更有可能经历各种类型的 ACE,并且更有可能经历 1 到 3 次或 4 次以上的 ACE。与没有经历过 ACE 的儿童相比,经历过 4+ ACE 的儿童被诊断为多动症的几率更高(aOR:3.44,95% CI [2.64,4.49])。男性儿童、健康状况一般或较差的儿童以及居住在农村地区的儿童更有可能被诊断出患有多动症,而有色人种儿童和没有保险的儿童则更有可能被诊断出患有多动症。我们发现,与无 ACE 的儿童相比,有四次或四次以上 ACE 的儿童被诊断为多动症的几率比略低于 Brown 等人 2017 年估计的 3.97(CI [3.29, 4.80])。这些结果表明,将COVID前的数据与COVID后的结果进行比较,ACE与ADHD之间存在一致的关联:这些发现强调了临床医生在筛查多动症时考虑创伤性压力的必要性。政策制定者和儿童早期组织应鼓励对 ACE 进行早期筛查和干预,以减少 ADHD 诊断的影响。
{"title":"Examining the Association Between Adverse Childhood Experiences and ADHD in School-Aged Children Following the COVID-19 Pandemic.","authors":"Emma Boswell, Elizabeth Crouch, Cassie Odahowski, Peiyin Hung","doi":"10.1177/10870547241290673","DOIUrl":"https://doi.org/10.1177/10870547241290673","url":null,"abstract":"<p><strong>Background: </strong>Adverse childhood experiences (ACEs) have long been associated with attention-deficit/hyperactive disorder (ADHD) diagnoses in children; but the data used is now over 6 years old (from 2017 to 2018). Understanding the current landscape of their prevalence and association is needed to capture evolving social, environmental, and economic conditions, and ensure interventions remain relevant to addressing current childhood trauma.</p><p><strong>Objective: </strong>This study provides an updated analysis of the association between ACEs and ADHD using post-acute-COVID-19 pandemic data.</p><p><strong>Participants and setting: </strong>This cross-sectional study of 10,518 children aged 5 to 17 years old derived data from the 2021 to 2022 National Health Interview Survey (NHIS).</p><p><strong>Methods: </strong>Differences in the prevalence of number (0, 1-3, or 4+) and type of ACEs by ADHD diagnosis were evaluated using Rao-Scott chi-square tests and multivariable logistic regression. All analyses incorporate complex survey weights.</p><p><strong>Results: </strong>In 2021 to 2022, 2,457 (23.3%) of children experienced ACEs and 1,115 (9.9%) had an ADHD diagnosis. Children with ADHD were more likely to experience every type of ACE and were more likely to have 1 to 3 or 4+ ACEs than children without ADHD. Children with 4+ ACEs had higher odds of having an ADHD diagnosis (aOR: 3.44, 95% CI [2.64, 4.49]) than children without ACEs. Male children, children with fair or poor health, and children living in rural counties were more likely to have an ADHD diagnosis, while children of color and uninsured children were less likely. We found the odds ratio of ADHD diagnosis for children with four or more ACEs, compared to those without ACEs, slightly lower than found in Brown et al., 2017's estimate of 3.97 (CI [3.29, 4.80]). These results suggest a consistent association between ACEs and ADHD when comparing pre-COVID data to our post-acute-COVID results.</p><p><strong>Conclusions: </strong>These findings highlight the need for clinicians to consider traumatic stress in ADHD screening. Policymakers and early childhood organizations should encourage early screening and intervention for ACEs to reduce the impacts of ADHD diagnoses.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547241290673"},"PeriodicalIF":2.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relations Between Distinct Dimensions of Physical Activity and Preschoolers' ADHD Symptoms. 体育活动的不同维度与学龄前儿童多动症症状之间的关系。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-18 DOI: 10.1177/10870547241288347
Erin K Shoulberg, Hannah Scott, Caroline P Martin, Connie L Tompkins, Marissa Dennis, Allison Krasner, Betsy Hoza

Objective: This study examined the unique and interactive effects of PA volume and within-person fluctuations in PA volume (i.e., intraindividual variability in PA volume; PA-var) on preschoolers' (N = 141; 47.5% girls) ADHD symptoms.

Method: Preschoolers wore accelerometers during the school day over a 2-week period. Teachers reported on children's hyperactive, impulsive, and inattentive symptoms on the ADHD Rating Scale-IV Preschool Version.

Results: In the context of regression models, higher levels of PA-var were linked with lower levels of impulsive symptoms. Higher levels of PA volume were linked with higher levels of hyperactive and inattentive symptoms, but only when PA fluctuation (i.e., PAvar) was relatively low. Post hoc analyses with teacher-reported impairment as the outcome revealed a significant interaction such that the positive association between PA volume and impairment was stronger at lower, as compared to higher, levels of PA-var.

Conclusion: Larger fluctuations in preschoolers' PA volume may indicate lower risk for displaying impulsive symptoms. Moreover, preschoolers with high levels of PA that remain relatively consistent throughout the day may be at increased risk for exhibiting hyperactive and inattentive symptoms and related impairment, suggesting they are unable to regulate their activity to meet expectations in the school environment.

研究目的本研究探讨了 PA 量和 PA 量的人内波动(即 PA 量的个体内变异性;PA-var)对学龄前儿童(N = 141;47.5% 为女孩)多动症状的独特和交互影响:方法:学龄前儿童在上学期间佩戴加速度计,为期两周。教师根据 ADHD 评定量表-IV 学龄前版本报告儿童的多动、冲动和注意力不集中症状:结果:在回归模型中,较高水平的 PAvar 与较低水平的冲动症状有关。较高水平的 PA 量与较高水平的多动和注意力不集中症状有关,但只有当 PA 波动(即 PAvar)相对较低时才有关联。以教师报告的障碍为结果进行的事后分析表明,在较低的 PAvar 水平下,PA 量与障碍之间的正相关性比在较高的 PAvar 水平下更强:结论:学龄前儿童的 PA 量波动越大,表明出现冲动症状的风险越低。此外,如果学龄前儿童的活动量水平较高,且在一天中保持相对稳定,那么他们表现出多动和注意力不集中症状及相关障碍的风险可能会增加,这表明他们无法调节自己的活动以满足学校环境中的期望。
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引用次数: 0
Causality Between ADHD, ASD, and CVDs: A Two-Step, Two-Sample Mendelian Randomization Investigation. 多动症、自闭症和心血管疾病之间的因果关系:两步双样本孟德尔随机调查。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-14 DOI: 10.1177/10870547241288741
Zequn Zheng, Dihui Cai

Background: While observational studies have established a connection between attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and heightened risk for cardiovascular diseases (CVD), the causal relationships are not well-defined. This study is designed to examine the causality between ASD, ADHD, and CVD risk as well as investigate the mediating factors through which ADHD and ASD influence CVD.

Methods and results: Leveraging two-sample Mendelian randomization (MR) approaches and large scale GWAS summary stats, we examined underlying causal links between ASD and ADHD and the risk of CVDs. The analysis indicated that ADHD was related to an increased likelihood of developing coronary heart disease (OR [95% CI] 1.12 [1.03, 1.21], p = .008), heart failure (OR [95% CI] 1.14 [1.07, 1.22], p = 1.45 × 10-4), and large-artery stroke (OR [95% CI] 1.35 [1.09, 1.66], p = .005). In parallel, ASD showed a correlation with a greater atrial fibrillation risk (OR [95% CI] 1.09 [1.03, 1.16], p = .005] and heart failure (OR [95% CI] 1.11 [1.04, 1.19], p = .004). Additionally, we explored the mediating role of CVD risk factors through two-step MR and multivariable MR, highlighting the possible role of smoking, prescription opioid use, triglycerides, education, income, Townsend deprivation index, and obesity in the causal association of ADHD, ASD, on CVDs.

Conclusion: This MR study highlights the necessity for rigorous cardiovascular surveillance and interventions to decrease adverse cardiovascular events in people with ADHD or ASD by preventing identified mediating risk factors.

背景:尽管观察性研究已证实注意缺陷多动障碍(ADHD)、自闭症谱系障碍(ASD)与心血管疾病(CVD)风险增加之间存在联系,但其因果关系尚未明确。本研究旨在探讨自闭症谱系障碍(ASD)、多动症(ADHD)与心血管疾病风险之间的因果关系,并研究多动症(ADHD)和自闭症谱系障碍(ASD)影响心血管疾病的中介因素:利用双样本孟德尔随机化(MR)方法和大规模 GWAS 总结统计,我们研究了 ASD 和 ADHD 与心血管疾病风险之间的潜在因果关系。分析表明,ADHD 与冠心病(OR [95% CI] 1.12 [1.03, 1.21],p = .008)、心力衰竭(OR [95% CI] 1.14 [1.07, 1.22],p = 1.45 × 10-4)和大动脉中风(OR [95% CI] 1.35 [1.09, 1.66],p = .005)的发病可能性增加有关。同时,ASD 与更高的心房颤动风险(OR [95% CI] 1.09 [1.03, 1.16],p = .005)和心力衰竭(OR [95% CI] 1.11 [1.04, 1.19],p = .004)相关。此外,我们还通过两步MR和多变量MR探讨了心血管疾病风险因素的中介作用,强调了吸烟、处方阿片类药物使用、甘油三酯、教育、收入、汤森剥夺指数和肥胖在ADHD、ASD与心血管疾病的因果关系中可能发挥的作用:这项磁共振研究强调了对心血管进行严格监测和干预的必要性,以通过预防已确定的中介风险因素来减少多动症或 ASD 患者的不良心血管事件。
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引用次数: 0
Adolescent-Reported Changes in Provider Behavior Following Pediatrician Training in Stimulant Diversion Prevention: Results From a Cluster Randomized Controlled Trial. 儿科医生接受兴奋剂转用预防培训后,青少年对提供者行为变化的报告:集群随机对照试验的结果。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-14 DOI: 10.1177/10870547241288744
Brooke S G Molina, Heather M Joseph, Heidi L Kipp, Sarah L Pedersen, David J Kolko, Rachel A Lindstrom, Daniel J Bauer, Geetha A Subramaniam

Objective: To test whether pediatrician training leads to provider utilization of stimulant diversion prevention strategies as reported by adolescent patients with ADHD.

Methods: Pediatric practices received a stimulant diversion prevention workshop (SDP) or continued treatment-as-usual (TAU) in a cluster-randomized controlled trial. Surveys were completed by 341 stimulant-treated patients at baseline and three follow-up assessments.

Results: In intent-to-treat analyses of patient reports, SDP adolescents reported more provider use of diversion prevention strategies compared to TAU. They also reported more parent-patient communication about diversion. Provider satisfaction with the training was strong.

Conclusions: Pediatricians can make use of clinical practice strategies for the prevention of stimulant diversion following a 1-hr training; findings are novel given their reliance on confidential patient report of provider behavior and increase confidence in the results. Coupled with the positive provider satisfaction ratings, results suggest that this brief workshop may be an option for concerned providers that also has the effect of increasing discussion at home about safe use of stimulants.

目的根据患有多动症的青少年患者的报告,检验儿科医生培训是否会促使医疗机构采用兴奋剂转用预防策略:在一项分组随机对照试验中,儿科医疗机构接受了兴奋剂转用预防研讨会(SDP)或继续照常治疗(TAU)。341名接受过兴奋剂治疗的患者在基线和三次随访评估时填写了调查问卷:结果:在对患者报告进行的意向治疗分析中,与 "照常治疗 "相比,"照常治疗 "的青少年报告称提供者使用了更多的转移预防策略。他们还报告说,家长与患者之间就转用问题进行了更多的沟通。提供者对培训的满意度很高:儿科医生在接受 1 小时的培训后,可以利用临床实践策略来预防兴奋剂转用;由于培训结果依赖于患者对提供者行为的保密报告,因此具有新颖性,并增强了对培训结果的信心。加上提供者的积极满意度评价,结果表明这个简短的研讨会可能是相关提供者的一个选择,同时还能增加家庭中关于安全使用兴奋剂的讨论。
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引用次数: 0
Mindful Awareness Practices (MAPs) in Adolescents With ADHD and Cognitive Disengagement Syndrome (CDS): A Pilot Open Trial. 多动症和认知脱离综合征(CDS)青少年的正念意识练习(MAPs):一项试点开放试验。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-14 DOI: 10.1177/10870547241290182
Kelsey K Wiggs, Keely Thornton, Nicholas C Dunn, John T Mitchell, Joseph W Fredrick, Zoe R Smith, Stephen P Becker

Objective: Very few studies have investigated intervention approaches that may be efficacious for youth with ADHD and co-occurring cognitive disengagement syndrome (CDS) symptoms. This study examined the feasibility, acceptability, and preliminary efficacy of a mindfulness-based intervention for adolescents with ADHD and co-occurring CDS symptoms. Methods: Fourteen adolescents ages 13 to 17 years (35.71% female; 64.29% White, 7.14% Black, 28.57% Multiracial) with ADHD and elevated CDS symptoms completed the 8-week group-based Mindful Awareness Practices (MAPs) program developed for individuals with ADHD. We collected measures of CDS, ADHD, mind-wandering, mindfulness, and other difficulties and functioning at baseline, 1-month post-intervention, and 3-month post-intervention to examine preliminary efficacy. We measured participant session attendance, session engagement, at-home practice adherence, and satisfaction of adolescents and caregivers at 1-month post-intervention to examine feasibility and acceptability. We also collected qualitative feedback from adolescents and caregivers at 1-month post-intervention. Results: The intervention was overall feasible to administer, and caregivers and adolescents reported satisfaction with the intervention despite some difficulties with attendance and engagement. We observed improvements to both caregiver- and adolescent-reported CDS symptoms and ADHD-inattentive symptoms from pre-intervention to post-intervention time points, though findings across 1- and 3-month follow-up differed based on informant. We also observed improvements to some indices of adolescent-reported mind-wandering, mindfulness, brooding rumination, and academic functioning. For caregiver report, the only other noted improvement was for executive functioning. No improvements were reported by teachers. Conclusions: Findings support the initial feasibility, acceptability, and preliminary efficacy of MAPs for adolescents with ADHD and co-occurring CDS symptoms on a range of outcomes. Larger trials with a randomized design are warranted to further examine mindfulness-based interventions for adolescents with ADHD and co-occurring CDS symptoms.

目的:很少有研究调查过对患有多动症(ADHD)并同时伴有认知分离综合征(CDS)症状的青少年有效的干预方法。本研究考察了对患有多动症并同时伴有认知脱离综合症(CDS)症状的青少年进行正念干预的可行性、可接受性和初步疗效。研究方法:14名年龄在13至17岁之间、患有多动症并伴有CDS症状的青少年(35.71%为女性;64.29%为白人,7.14%为黑人,28.57%为多种族)完成了为多动症患者开发的为期8周的正念练习(MAPs)小组项目。我们收集了基线、干预后 1 个月和干预后 3 个月的 CDS、ADHD、思维游离、正念及其他困难和功能的测量数据,以检验初步疗效。我们在干预后 1 个月测量了参与者的课程出勤率、课程参与度、在家练习的坚持度以及青少年和照顾者的满意度,以考察其可行性和可接受性。我们还收集了青少年和护理人员在干预后 1 个月的定性反馈。结果:干预的实施总体上是可行的,尽管在出席和参与方面存在一些困难,但照护者和青少年对干预表示满意。我们观察到,从干预前到干预后,照顾者和青少年报告的CDS症状和ADHD注意力不集中症状都有所改善,但1个月和3个月的随访结果因提供信息者的不同而有所差异。我们还观察到,青少年报告的某些思想游荡、正念、忧郁反刍和学习功能指数有所改善。在照顾者的报告中,我们只注意到执行功能有所改善。教师没有报告任何改善。结论研究结果表明,MAPs 对患有多动症并同时伴有 CDS 症状的青少年具有初步的可行性、可接受性和初步疗效。有必要进行更大规模的随机设计试验,以进一步研究针对患有多动症和合并 CDS 症状的青少年的正念干预措施。
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引用次数: 0
Diabetes Glycemic Control in Adults With Type 2 Diabetes Mellitus and ADHD. 2 型糖尿病合并多动症成人的血糖控制。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-10-10 DOI: 10.1177/10870547241288720
Dahlia Leshno, Liat Lev Shalem, Revital Perlove Gavze, Moshe Leshno

Introduction: Persistence in treatment is important in balancing diabetes and preventing complications. ADHD impairs quality of life and functioning in many areas of life. The aim of this study is to evaluate the possible association of ADHD and diabetes glycemic control among adults with type 2 diabetes mellitus (T2DM).

Methods: All data were obtained from Maccabi Healthcare Services (MHS) automated databases. This retrospective cross-sectional study uses electronic medical records from the Maccabi Healthcare Services database during the years 2010 to 2020. Using a propensity score with the variables of age, gender, and duration of diabetes, we compared a group of 1,582 patients with T2DM and ADHD to 1,582 patients with T2DM and without ADHD. We used a t-test to compare continuous variables and a Mann-Whitney U test for non-parametric testing. In addition, we used multivariate logistic regression with a cutoff of several HbA1c values in T2DM patients with and without ADHD during 2019 to 2020. The proportion of patients with HbA1c values above 10%, 9%, and 8% in the group of patients with ADHD was 4.7 to 5.9 times higher than in patients without ADHD. In addition, the OR in the multivariate logistic regression was 4.2 (95% CI [2.5, 6.8]), 4.3 (95% CI [3.1, 6.1]), and 2.7 (95% CI [2.2, 3.4]) for cutoff of HbA1c of 10%, 9%, and 8%, respectively.

Conclusion: Patients with co-morbid ADHD and T2DM have a higher incidence of poor glycemic control. The findings extend the knowledge on the relationship between ADHD and diabetes and highlight the need for further research to improve treatment.

介绍:坚持治疗对于平衡糖尿病和预防并发症非常重要。多动症会损害生活质量和许多生活领域的功能。本研究旨在评估多动症与 2 型糖尿病(T2DM)成人患者的血糖控制之间可能存在的关联:所有数据均来自马卡比医疗保健服务(Maccabi Healthcare Services,MHS)的自动数据库。这项回顾性横断面研究使用了马卡比医疗保健服务数据库中 2010 年至 2020 年的电子病历。通过使用年龄、性别和糖尿病病程等变量进行倾向评分,我们将 1582 名患有 T2DM 和多动症的患者与 1582 名患有 T2DM 但不患有多动症的患者进行了比较。我们使用 t 检验比较连续变量,使用 Mann-Whitney U 检验进行非参数检验。此外,我们还使用了多变量逻辑回归,以2019年至2020年期间有多动症和无多动症的T2DM患者的几个HbA1c值为临界值。多动症患者组中HbA1c值高于10%、9%和8%的患者比例是无多动症患者的4.7至5.9倍。此外,在多变量逻辑回归中,HbA1c 临界值为 10%、9% 和 8% 的 OR 分别为 4.2(95% CI [2.5,6.8])、4.3(95% CI [3.1,6.1])和 2.7(95% CI [2.2,3.4]):结论:合并多动症和 T2DM 的患者血糖控制不佳的发生率较高。研究结果拓展了人们对多动症与糖尿病之间关系的认识,并强调了进一步研究以改善治疗的必要性。
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引用次数: 0
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Journal of Attention Disorders
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