Pub Date : 2026-02-01Epub Date: 2025-09-25DOI: 10.1177/10870547251370427
Fikriye Eda Karaçul, Gökmen Arslan
Background: Adverse childhood experiences (ACEs) are known to have several negative effects on mental health and well-being. However, few studies have examined the role of these events in the development of ADHD and the protective factors that could guide prevention and intervention strategies in college students. The aim of current study is to examine the potential role of self-compassion and emotion regulation in the relationship between ACEs and ADHD symptoms in college students. Method: The sample of the study consisted of 442 young adults (67.4% female; 32.6% male) aged between 18 and 29 years (M = 20.43, SD = 1.74) from a public university in Türkiye. Participants completed validated measures that were combined in a single battery with a web-based tool. Results: We found that ACEs were associated with lower levels of self-compassion (Cohen's d = 0.43) and emotion regulation (Cohen's d = 0.29), along with higher levels of attention deficit (Cohen's d = 0.47) and hyperactivity-impulsivity (Cohen's d = 0.46) symptoms. Further results indicated that ACEs were a significant positive predictor of attention deficit and hyperactivity-impulsivity symptoms and a negative predictor of self-compassion and emotion regulation. Additionally, self-compassion showed an indirect effect on the relationship between ACEs and emotion regulation, as well as the association between ACEs and attention-deficit/hyperactivity-impulsivity symptoms. Finally, we found that emotion regulation had an indirect effect on the association between self-compassion and attention-deficit/hyperactivity-impulsivity symptoms. Conclusion: These findings provide further evidence supporting the importance of self-compassion-based strategies to reduce attention-deficit/hyperactivity impulsivity by promoting emotion regulation skills in college students.
背景:众所周知,不良童年经历(ace)对心理健康和幸福有几种负面影响。然而,很少有研究检查这些事件在ADHD发展中的作用,以及可以指导大学生预防和干预策略的保护因素。本研究旨在探讨自我同情和情绪调节在大学生ace与ADHD症状之间的潜在作用。方法:研究样本为来自日本一所公立大学的年龄在18 ~ 29岁的青年442人(女性67.4%,男性32.6%),M = 20.43, SD = 1.74。参与者完成了经过验证的测量,这些测量与基于网络的工具结合在一起。结果:我们发现,ace与较低水平的自我同情(Cohen’s d = 0.43)和情绪调节(Cohen’s d = 0.29),以及较高水平的注意力缺陷(Cohen’s d = 0.47)和多动冲动(Cohen’s d = 0.46)症状有关。进一步的结果表明,ace是注意缺陷和多动冲动症状的显著正向预测因子,是自我同情和情绪调节的显著负向预测因子。此外,自我同情对ace与情绪调节之间的关系以及ace与注意缺陷/多动冲动症状之间的关系具有间接影响。最后,我们发现情绪调节对自我同情与注意缺陷/多动冲动症状之间的关联有间接影响。结论:这些发现进一步证明了基于自我同情的策略通过提高大学生的情绪调节技能来减少注意缺陷/多动冲动的重要性。
{"title":"Adverse Childhood Experiences and ADHD in College Students: Exploring the Role of Emotion Regulation and Self-Compassion.","authors":"Fikriye Eda Karaçul, Gökmen Arslan","doi":"10.1177/10870547251370427","DOIUrl":"10.1177/10870547251370427","url":null,"abstract":"<p><p><b>Background:</b> Adverse childhood experiences (ACEs) are known to have several negative effects on mental health and well-being. However, few studies have examined the role of these events in the development of ADHD and the protective factors that could guide prevention and intervention strategies in college students. The aim of current study is to examine the potential role of self-compassion and emotion regulation in the relationship between ACEs and ADHD symptoms in college students. <b>Method:</b> The sample of the study consisted of 442 young adults (67.4% female; 32.6% male) aged between 18 and 29 years (<i>M</i> = 20.43, <i>SD</i> = 1.74) from a public university in Türkiye. Participants completed validated measures that were combined in a single battery with a web-based tool. <b>Results:</b> We found that ACEs were associated with lower levels of self-compassion (Cohen's <i>d</i> = 0.43) and emotion regulation (Cohen's <i>d</i> = 0.29), along with higher levels of attention deficit (Cohen's <i>d</i> = 0.47) and hyperactivity-impulsivity (Cohen's <i>d</i> = 0.46) symptoms. Further results indicated that ACEs were a significant positive predictor of attention deficit and hyperactivity-impulsivity symptoms and a negative predictor of self-compassion and emotion regulation. Additionally, self-compassion showed an indirect effect on the relationship between ACEs and emotion regulation, as well as the association between ACEs and attention-deficit/hyperactivity-impulsivity symptoms. Finally, we found that emotion regulation had an indirect effect on the association between self-compassion and attention-deficit/hyperactivity-impulsivity symptoms. <b>Conclusion:</b> These findings provide further evidence supporting the importance of self-compassion-based strategies to reduce attention-deficit/hyperactivity impulsivity by promoting emotion regulation skills in college students.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"181-192"},"PeriodicalIF":2.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-11-28DOI: 10.1177/10870547251389337
Patrick K Goh, Sara Chung, Nandini Jhawar, Ashlyn W W A Wong, Grace S Mellor, Meeta Banerjee, Cynthia M Hartung
Objective: The Asian American and Native Hawaiian/Pacific Islander (AA & NH/PI) population represents one of the fastest-growing racial /ethnic groups in the United States, yet members of this community are among the least likely to receive services for ADHD. Studies seeking to explain discrepancies between the need for and use of ADHD services in AA & NH/PI populations have highlighted decreased problem recognition as precluding access to services. We sought to investigate the roles of three previously proposed factors (i.e., perceived impairment, ADHD knowledge, and ADHD stigma) in explaining differences in ADHD problem recognition in AA & NH/PI versus White, Black, Hispanic/Latinx, and Multiracial/Multiethnic college students.
Method: Participants were 1,451 college students aged 18 to 29 years (M = 19.3, SD = 1.64) who met self-reported symptom and impairment criteria for ADHD. They completed questionnaires assessing ADHD problem recognition, perceived impairment, ADHD knowledge, and ADHD stigma.
Results: Compared to the White Group, the AA & NH/PI Group had significantly lower probability of endorsing the belief that they should be diagnosed with ADHD. The AA & NH/PI Group also reported lower levels of ADHD knowledge and increased levels of ADHD stigma and perceived impairment compared to the White Group. Increased ADHD knowledge was associated with greater likelihood of ADHD problem recognition. Examination of indirect effects suggested that differences in ADHD problem recognition between AA & NH/PI and White Groups were partially explained by differences in ADHD knowledge.
Conclusion: Results highlighted the importance of clarifying mechanisms underlying ADHD-related service-use patterns in AA & NH/PI populations to better understand and address mental health needs.
{"title":"ADHD Knowledge as a Barrier to Problem Recognition in Asian American and Native Hawaiian/Pacific Islander Versus White College Students.","authors":"Patrick K Goh, Sara Chung, Nandini Jhawar, Ashlyn W W A Wong, Grace S Mellor, Meeta Banerjee, Cynthia M Hartung","doi":"10.1177/10870547251389337","DOIUrl":"10.1177/10870547251389337","url":null,"abstract":"<p><strong>Objective: </strong>The Asian American and Native Hawaiian/Pacific Islander (AA & NH/PI) population represents one of the fastest-growing racial /ethnic groups in the United States, yet members of this community are among the least likely to receive services for ADHD. Studies seeking to explain discrepancies between the need for and use of ADHD services in AA & NH/PI populations have highlighted decreased problem recognition as precluding access to services. We sought to investigate the roles of three previously proposed factors (i.e., perceived impairment, ADHD knowledge, and ADHD stigma) in explaining differences in ADHD problem recognition in AA & NH/PI versus White, Black, Hispanic/Latinx, and Multiracial/Multiethnic college students.</p><p><strong>Method: </strong>Participants were 1,451 college students aged 18 to 29 years (<i>M</i> = 19.3, <i>SD</i> = 1.64) who met self-reported symptom and impairment criteria for ADHD. They completed questionnaires assessing ADHD problem recognition, perceived impairment, ADHD knowledge, and ADHD stigma.</p><p><strong>Results: </strong>Compared to the White Group, the AA & NH/PI Group had significantly lower probability of endorsing the belief that they should be diagnosed with ADHD. The AA & NH/PI Group also reported lower levels of ADHD knowledge and increased levels of ADHD stigma and perceived impairment compared to the White Group. Increased ADHD knowledge was associated with greater likelihood of ADHD problem recognition. Examination of indirect effects suggested that differences in ADHD problem recognition between AA & NH/PI and White Groups were partially explained by differences in ADHD knowledge.</p><p><strong>Conclusion: </strong>Results highlighted the importance of clarifying mechanisms underlying ADHD-related service-use patterns in AA & NH/PI populations to better understand and address mental health needs.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"234-248"},"PeriodicalIF":2.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-01Epub Date: 2025-12-30DOI: 10.1177/10870547251405545
Laura J Holt, Alison Looby, Richard Feinn, Ty S Schepis
Prescription stimulant diversion (i.e., giving, selling, or trading one's medication) and non-medical prescription stimulant use (i.e., using in ways not prescribed) are common among undergraduates; however, few evidence-based interventions target these behaviors. This study evaluated the efficacy and feasibility of a 30-min, interactive web-based intervention providing psychoeducation around diversion and non-medical use, practice refusing medication requests, and medication adherence strategies. Students (Mage = 20.42 years; 74% female; 86% White) with current stimulant prescriptions from three US universities were randomized to the intervention (n = 128) or attention-matched placebo (n = 121) in a single-blind design, with 1- and 2-month boosters and 3- and 6-month follow-ups. Primary outcomes were diversion, non-medical use, and diversion intentions; secondary outcomes were perceived norms, perceived risk, self-efficacy to resist diversion and non-medical use, and prescriber communication. Contrary to pre-registered hypotheses, intervention participants did not report decreases in primary outcomes. There were small-to-medium effects on secondary outcomes of risk perceptions (d = 0.39 [0.12, 0.68]), perceived non-medical use norms (d = 0.51 [0.24, 0.76]), and self-efficacy to avoid non-medical use (d = 0.47 [0.10, 0.85]), but not on perceived diversion norms, self-efficacy to avoid diversion, and prescriber communication. Post-hoc analyses showed a 76% reduction in odds of any diversion (OR = 0.24 [0.08, 0.68]) and a 60% reduction of any non-medical use (OR = 0.40 [0.21, 0.77]) for intervention participants during the 6-month follow-up period. This intervention was acceptable and feasible to implement and evidenced some efficacy in modifying risk perceptions, self-efficacy, and perceived norms. Since diversion and misuse episodes were not reduced, future intervention refinements may tailor content to different levels of diversion and misuse risk. Registered in ClinicalTrials.gov on May 12, 2021: NCT04885166.
{"title":"Preventing Prescription Stimulant Diversion and Misuse via a Web-Based Intervention: A Randomized Controlled Trial.","authors":"Laura J Holt, Alison Looby, Richard Feinn, Ty S Schepis","doi":"10.1177/10870547251405545","DOIUrl":"10.1177/10870547251405545","url":null,"abstract":"<p><p>Prescription stimulant diversion (i.e., giving, selling, or trading one's medication) and non-medical prescription stimulant use (i.e., using in ways not prescribed) are common among undergraduates; however, few evidence-based interventions target these behaviors. This study evaluated the efficacy and feasibility of a 30-min, interactive web-based intervention providing psychoeducation around diversion and non-medical use, practice refusing medication requests, and medication adherence strategies. Students (<i>M</i><sub>age</sub> = 20.42 years; 74% female; 86% White) with current stimulant prescriptions from three US universities were randomized to the intervention (<i>n</i> = 128) or attention-matched placebo (<i>n</i> = 121) in a single-blind design, with 1- and 2-month boosters and 3- and 6-month follow-ups. Primary outcomes were diversion, non-medical use, and diversion intentions; secondary outcomes were perceived norms, perceived risk, self-efficacy to resist diversion and non-medical use, and prescriber communication. Contrary to pre-registered hypotheses, intervention participants did not report decreases in primary outcomes. There were small-to-medium effects on secondary outcomes of risk perceptions (<i>d</i> = 0.39 [0.12, 0.68]), perceived non-medical use norms (<i>d</i> = 0.51 [0.24, 0.76]), and self-efficacy to avoid non-medical use (<i>d</i> = 0.47 [0.10, 0.85]), but not on perceived diversion norms, self-efficacy to avoid diversion, and prescriber communication. Post-hoc analyses showed a 76% reduction in odds of <i>any</i> diversion (<i>OR</i> = 0.24 [0.08, 0.68]) and a 60% reduction of <i>any</i> non-medical use (<i>OR</i> = 0.40 [0.21, 0.77]) for intervention participants during the 6-month follow-up period. This intervention was acceptable and feasible to implement and evidenced some efficacy in modifying risk perceptions, self-efficacy, and perceived norms. Since diversion and misuse episodes were not reduced, future intervention refinements may tailor content to different levels of diversion and misuse risk. Registered in ClinicalTrials.gov on May 12, 2021: NCT04885166.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"265-280"},"PeriodicalIF":2.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145856477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-29DOI: 10.1177/10870547261416163
Brent R Carr
Background: Since DSM-5, ADHD has been classified as a neurodevelopmental disorder, and this placement has often reinforced dominant models that emphasize neurobiological mechanisms-treating attention as an internal trait shaped by executive dysfunction or dopaminergic imbalance. While these frameworks offer valuable insights, they often marginalize the ecological, relational, and sociomaterial contexts in which attention arises or collapses. Context is too often treated as background rather than condition.
Objective: This paper proposes a field-based reconceptualization of attention: a relational ontology in which patterns of behavior and experience gathered under the ADHD diagnosis are not solely located within the individual but emerge from dynamic tension between organism and environment.
Methods: Drawing from ecological psychology, dynamic systems theory, and phenomenological psychiatry, we develop the notion of fielded attention-a model in which attention is not a fixed trait but a modulation shaped by rhythm, affordance, and environmental curvature. We conduct a conceptual analysis in three stages: (1) critique of trait-based diagnostic frameworks that statistically neutralize context; (2) elaboration of a field ontology of attention that reframes breakdowns as ruptures in relational coherence; and (3) derivation of translational implications for research and care design.
Results: The analysis identifies an epistemic shift in which environmental and social structures are often flattened into reductionist risk factors, and heterogeneity in ADHD symptom expression is reframed as field sensitivity-a signal of developmental plasticity rather than diagnostic noise. Translational implications include the design of learning and care environments (including architectural and temporal structure) and adoption of field-sensitive research methods such as ecological momentary assessment and spatial diaries.
Conclusions: Rather than reject biological models, this framework resituates them within broader ecologies of modulation. By repositioning context as ontologically central, fielded attention advances a more ethically responsive and developmentally situated account of ADHD.
{"title":"Fielded Attention: Reframing ADHD Through a Relational Ontology of Context.","authors":"Brent R Carr","doi":"10.1177/10870547261416163","DOIUrl":"https://doi.org/10.1177/10870547261416163","url":null,"abstract":"<p><strong>Background: </strong>Since DSM-5, ADHD has been classified as a neurodevelopmental disorder, and this placement has often reinforced dominant models that emphasize neurobiological mechanisms-treating attention as an internal trait shaped by executive dysfunction or dopaminergic imbalance. While these frameworks offer valuable insights, they often marginalize the ecological, relational, and sociomaterial contexts in which attention arises or collapses. Context is too often treated as background rather than condition.</p><p><strong>Objective: </strong>This paper proposes a field-based reconceptualization of attention: a relational ontology in which patterns of behavior and experience gathered under the ADHD diagnosis are not solely located within the individual but emerge from dynamic tension between organism and environment.</p><p><strong>Methods: </strong>Drawing from ecological psychology, dynamic systems theory, and phenomenological psychiatry, we develop the notion of <i>fielded attention</i>-a model in which attention is not a fixed trait but a modulation shaped by rhythm, affordance, and environmental curvature. We conduct a conceptual analysis in three stages: (1) critique of trait-based diagnostic frameworks that statistically neutralize context; (2) elaboration of a field ontology of attention that reframes breakdowns as ruptures in relational coherence; and (3) derivation of translational implications for research and care design.</p><p><strong>Results: </strong>The analysis identifies an epistemic shift in which environmental and social structures are often flattened into reductionist risk factors, and heterogeneity in ADHD symptom expression is reframed as field sensitivity-a signal of developmental plasticity rather than diagnostic noise. Translational implications include the design of learning and care environments (including architectural and temporal structure) and adoption of field-sensitive research methods such as ecological momentary assessment and spatial diaries.</p><p><strong>Conclusions: </strong>Rather than reject biological models, this framework resituates them within broader ecologies of modulation. By repositioning context as ontologically central, <i>fielded attention</i> advances a more ethically responsive and developmentally situated account of ADHD.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547261416163"},"PeriodicalIF":2.2,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-26DOI: 10.1177/10870547251415431
Taylor K Hanes, Ann Christin Andersen, Bianca E Boyer, Kyle Wagner
Objective: This study investigates the effectiveness of Cognitive Behavioral Therapy (CBT) for adolescents with ADHD, while focusing on gender differences and comorbid internalizing symptoms.
Method: A quantitative secondary data analysis was performed on 200 adolescents aged 12 to 18 years who participated in randomized control trials in either the Netherlands or Norway.
Results: Overall, CBT significantly reduced ADHD symptoms from pretest to posttest on parent measures; however, treatment response varied based on gender, internalizing symptoms, and treatment formats. Girls with elevated depression showed significantly smaller reductions in ADHD symptoms compared to boys with similar depressive profiles (p = .02), even after controlling for baseline ADHD severity. Effect size analyses revealed that girls benefited from both CBT delivery formats, but symptom improvement was nearly twice as large in individual CBT (d = 0.90, large effect) compared to group CBT (d = 0.49, moderate effect).
Conclusion: These findings suggest that depression may impact treatment response among girls, and that individual CBT may offer enhanced benefits for adolescent girls with ADHD.
{"title":"Gender Differences in Cognitive Behavioral Therapy Outcomes for Adolescents With ADHD: Examining the Impact of Internalizing Symptoms.","authors":"Taylor K Hanes, Ann Christin Andersen, Bianca E Boyer, Kyle Wagner","doi":"10.1177/10870547251415431","DOIUrl":"https://doi.org/10.1177/10870547251415431","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the effectiveness of Cognitive Behavioral Therapy (CBT) for adolescents with ADHD, while focusing on gender differences and comorbid internalizing symptoms.</p><p><strong>Method: </strong>A quantitative secondary data analysis was performed on 200 adolescents aged 12 to 18 years who participated in randomized control trials in either the Netherlands or Norway.</p><p><strong>Results: </strong>Overall, CBT significantly reduced ADHD symptoms from pretest to posttest on parent measures; however, treatment response varied based on gender, internalizing symptoms, and treatment formats. Girls with elevated depression showed significantly smaller reductions in ADHD symptoms compared to boys with similar depressive profiles (<i>p</i> = .02), even after controlling for baseline ADHD severity. Effect size analyses revealed that girls benefited from both CBT delivery formats, but symptom improvement was nearly twice as large in individual CBT (<i>d</i> = 0.90, large effect) compared to group CBT (<i>d</i> = 0.49, moderate effect).</p><p><strong>Conclusion: </strong>These findings suggest that depression may impact treatment response among girls, and that individual CBT may offer enhanced benefits for adolescent girls with ADHD.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251415431"},"PeriodicalIF":2.2,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146052187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1177/10870547251397701
Jennifer M Loftis, Hayleigh K Ast, Alisha M Bruton, Priya Srikanth, Ramya Ramesh, David W Erikson, Lisa M Robinette, Irene E Hatsu, Brenda M Y Leung, Taryn A Machingo, L Eugene Arnold, Jeanette M Johnstone
Objective: While individual nutrients have shown effects on inflammatory mechanisms, the effects of multinutrients (vitamins + minerals, antioxidants, and amino acids) on inflammation are unknown. We investigated whether 8 weeks of multinutrient supplementation, in a randomized controlled trial of 83 children with ADHD, would alter immune factors compared to placebo.
Methods: Multiplex technology was used to measure 25 immune factors in blood samples collected at baseline and week 8. Immune factors were compared between multinutrient and placebo groups using the Mann-Whitney test. Linear mixed effects models evaluated immune factor change over time. To understand the functional relevance of the immune factors affected by multinutrient supplementation, pathway analysis was performed using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) v6.7 Bioinformatics Resources.
Results: Interleukin (IL)-5 and IL-13 levels differed following multinutrient supplementation versus placebo (p = .005 and .03, respectively). IL-5 decreased by 1.3% in the multinutrient group (95% CI [-8.6%, 6.7%]) and increased by 17.5% in the placebo group (95% CI [6.9%, 29.2%]). IL-13 decreased by 11.4% in the multinutrient group (95% CI [-18.2%, -4.0%]), compared to a 2.4% increase in the placebo group (95% CI [-7.2%, 13.1%]). When comparing immune factors between treatment responders versus non-responders in the multinutrient group, there was a 4.3% increase in IL-15 in multinutrient responders (95% CI [-6.8%, 16.8%]) and a 14.3% decrease in non-responders (p = .03, 95% CI [-24.9%, -2.4%]). Pathway analysis identified T helper type 2 (Th2) signaling pathways affected by multinutrient supplementation, including IL-17 and cytokine-cytokine receptor interaction pathways.
Conclusion: Th2 immune factors may be influenced by multinutrient supplementation and associated with behavioral improvements in ADHD.
{"title":"Multinutrient Supplementation in Children With ADHD Reduced Pro- and Anti-Inflammatory Immune Factors in the MADDY Randomized Controlled Trial.","authors":"Jennifer M Loftis, Hayleigh K Ast, Alisha M Bruton, Priya Srikanth, Ramya Ramesh, David W Erikson, Lisa M Robinette, Irene E Hatsu, Brenda M Y Leung, Taryn A Machingo, L Eugene Arnold, Jeanette M Johnstone","doi":"10.1177/10870547251397701","DOIUrl":"https://doi.org/10.1177/10870547251397701","url":null,"abstract":"<p><strong>Objective: </strong>While individual nutrients have shown effects on inflammatory mechanisms, the effects of multinutrients (vitamins + minerals, antioxidants, and amino acids) on inflammation are unknown. We investigated whether 8 weeks of multinutrient supplementation, in a randomized controlled trial of 83 children with ADHD, would alter immune factors compared to placebo.</p><p><strong>Methods: </strong>Multiplex technology was used to measure 25 immune factors in blood samples collected at baseline and week 8. Immune factors were compared between multinutrient and placebo groups using the Mann-Whitney test. Linear mixed effects models evaluated immune factor change over time. To understand the functional relevance of the immune factors affected by multinutrient supplementation, pathway analysis was performed using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) v6.7 Bioinformatics Resources.</p><p><strong>Results: </strong>Interleukin (IL)-5 and IL-13 levels differed following multinutrient supplementation versus placebo (<i>p</i> = .005 and .03, respectively). IL-5 decreased by 1.3% in the multinutrient group (95% CI [-8.6%, 6.7%]) and increased by 17.5% in the placebo group (95% CI [6.9%, 29.2%]). IL-13 decreased by 11.4% in the multinutrient group (95% CI [-18.2%, -4.0%]), compared to a 2.4% increase in the placebo group (95% CI [-7.2%, 13.1%]). When comparing immune factors between treatment responders versus non-responders in the multinutrient group, there was a 4.3% increase in IL-15 in multinutrient responders (95% CI [-6.8%, 16.8%]) and a 14.3% decrease in non-responders (<i>p</i> = .03, 95% CI [-24.9%, -2.4%]). Pathway analysis identified T helper type 2 (Th2) signaling pathways affected by multinutrient supplementation, including IL-17 and cytokine-cytokine receptor interaction pathways.</p><p><strong>Conclusion: </strong>Th2 immune factors may be influenced by multinutrient supplementation and associated with behavioral improvements in ADHD.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251397701"},"PeriodicalIF":2.2,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1177/10870547251412660
Brittany J Taylor, Ann DiGirolamo, Angela Snyder, Colleen Smith, Angelika H Claussen, Helena J Hutchins, Amanda Phillips Martinez
Objective: The American Academy of Pediatrics (AAP) recommends behavioral therapy as first-line evidence-based treatment for young children with ADHD, and in combination with medications for children ages 6 years and older. However, a significant percentage of young children are receiving medication treatment for ADHD rather than behavioral treatment. There is limited research capturing parent experiences of barriers to implementing behavioral health services for young children with ADHD diagnoses. This paper seeks to fill this gap by exploring these perceived barriers among parents of children diagnosed with ADHD.
Method: Parents of children with ADHD diagnoses (N = 29) were invited to participate in four focus groups to discuss their experiences with accessing treatment for their child. Focus group participants were recruited from one Southeast city through an ADHD parental support group and nationally from parents attending a conference on ADHD.
Results: Three themes emerged as perceived barriers that impact ADHD treatment. Parents reported barriers that can be conceptualized as (1) misconceptions and stigma; (2) availability of financial and time-related resources; and (3) treatment messaging and provider coordination. These barriers may be more pronounced for parents of young children with ADHD living in the Southeast.
Conclusion: Parent responses about perceived barriers in this study suggest a need for better coordinated care of ADHD across places of service, providers, and families. These findings may inform future efforts to improve access to and utilization of evidence-based treatments for ADHD in the Southeast and nationwide.
{"title":"Parent Perspectives on Barriers to Behavioral Health Services for Children With ADHD.","authors":"Brittany J Taylor, Ann DiGirolamo, Angela Snyder, Colleen Smith, Angelika H Claussen, Helena J Hutchins, Amanda Phillips Martinez","doi":"10.1177/10870547251412660","DOIUrl":"https://doi.org/10.1177/10870547251412660","url":null,"abstract":"<p><strong>Objective: </strong>The American Academy of Pediatrics (AAP) recommends behavioral therapy as first-line evidence-based treatment for young children with ADHD, and in combination with medications for children ages 6 years and older. However, a significant percentage of young children are receiving medication treatment for ADHD rather than behavioral treatment. There is limited research capturing parent experiences of barriers to implementing behavioral health services for young children with ADHD diagnoses. This paper seeks to fill this gap by exploring these perceived barriers among parents of children diagnosed with ADHD.</p><p><strong>Method: </strong>Parents of children with ADHD diagnoses (<i>N</i> = 29) were invited to participate in four focus groups to discuss their experiences with accessing treatment for their child. Focus group participants were recruited from one Southeast city through an ADHD parental support group and nationally from parents attending a conference on ADHD.</p><p><strong>Results: </strong>Three themes emerged as perceived barriers that impact ADHD treatment. Parents reported barriers that can be conceptualized as (1) misconceptions and stigma; (2) availability of financial and time-related resources; and (3) treatment messaging and provider coordination. These barriers may be more pronounced for parents of young children with ADHD living in the Southeast.</p><p><strong>Conclusion: </strong>Parent responses about perceived barriers in this study suggest a need for better coordinated care of ADHD across places of service, providers, and families. These findings may inform future efforts to improve access to and utilization of evidence-based treatments for ADHD in the Southeast and nationwide.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251412660"},"PeriodicalIF":2.2,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1177/10870547251409862
Marushka R Rout, Ava Gaddis, Carlos E Yeguez, Margaret H Sibley, Nicole B Groves
Objective: At least a third of U.S. adults with ADHD do not access recommended treatments (medication or cognitive behavioral therapy [CBT]), and those receiving treatment face barriers (e.g., inconsistent availability of medication). We investigated systemic inequities in CBT access for adults with ADHD versus psychiatric diagnoses with similar prevalence.
Method: We accessed and extracted publicly available listings from the Psychology Interjurisdictional Compact (PSYPACT) provider directory (N= 12,898) in April 2025.
Results: Only 26.4% of PSYPACT providers explicitly offer any services for adult ADHD. They were nearly three times more likely to treat adult depression (69.2%) and anxiety (74.0%). CBT for adult ADHD was offered by just 21.3% of providers.
Conclusion: U.S. psychologists are chief CBT providers for adult mental disorders; however, they systemically underserve adults with ADHD. Contributors to this inequity must be identified to advance adult ADHD care, as untreated ADHD is a costly public health burden.
{"title":"Disparities in Adult ADHD Care Delivery Among U.S. Telepsychology Providers.","authors":"Marushka R Rout, Ava Gaddis, Carlos E Yeguez, Margaret H Sibley, Nicole B Groves","doi":"10.1177/10870547251409862","DOIUrl":"https://doi.org/10.1177/10870547251409862","url":null,"abstract":"<p><strong>Objective: </strong>At least a third of U.S. adults with ADHD do not access recommended treatments (medication or cognitive behavioral therapy [CBT]), and those receiving treatment face barriers (e.g., inconsistent availability of medication). We investigated systemic inequities in CBT access for adults with ADHD versus psychiatric diagnoses with similar prevalence.</p><p><strong>Method: </strong>We accessed and extracted publicly available listings from the Psychology Interjurisdictional Compact (PSYPACT) provider directory (<i>N</i> <i>=</i> 12,898) in April 2025.</p><p><strong>Results: </strong>Only 26.4% of PSYPACT providers explicitly offer any services for adult ADHD. They were nearly three times more likely to treat adult depression (69.2%) and anxiety (74.0%). CBT for adult ADHD was offered by just 21.3% of providers.</p><p><strong>Conclusion: </strong>U.S. psychologists are chief CBT providers for adult mental disorders; however, they systemically underserve adults with ADHD. Contributors to this inequity must be identified to advance adult ADHD care, as untreated ADHD is a costly public health burden.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251409862"},"PeriodicalIF":2.2,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To estimate the adherence of children and adults to oral stimulant ADHD treatments in Sweden during the period 2015 to 2020.
Methods: This retrospective, nationwide, register-based study evaluated all patients who were dispensed oral formulation stimulants (Anatomical Therapeutic Chemical [ATC] codes: N06BA01, N06BA02, N06BA04, N06BA12) identified in the Swedish Prescribed Drug Register. Treatment episodes were constructed based on drug dispensation data, and treatment adherence was calculated for each treatment episode using a Proportion of Days Covered approach with a modified one-pill-a-day method.
Results: Between 2015 and 2020, 158,413 treatment episodes were recorded in 128,366 patients, corresponding to a median 1.23 treatment episodes per patient. The majority of treatment episodes involved methylphenidate (64.0%), followed by lisdexamfetamine (32.2%), dexamfetamine (3.0%), and amphetamine (0.8%). Overall treatment adherence was high (78.2%), and was similar for patients receiving methylphenidate, lisdexamfetamine, and dexamfetamine. The proportion of patients with ≥80% medication adherence was high (69.3%-71.8%) for adults aged ≥25 years, but was low for adolescents aged 12 to 17 years (49.7%-52.4%).
Conclusions: The overall rates of treatment adherence are high for children and adults receiving ADHD medication in Sweden. We observed lower adherence among adolescents, which warrants further study.
{"title":"Medication Adherence in Children and Adults Receiving Treatment for Attention Deficit Hyperactivity Disorder (ADHD) in Sweden: A Nationwide Study.","authors":"MaiBritt Giacobini, Jingcheng Zhao, Jonatan Freilich, Carolina Brünner, Niklas Wallin Bernhardsson, Ewa Ahnemark","doi":"10.1177/10870547251406760","DOIUrl":"https://doi.org/10.1177/10870547251406760","url":null,"abstract":"<p><strong>Objective: </strong>To estimate the adherence of children and adults to oral stimulant ADHD treatments in Sweden during the period 2015 to 2020.</p><p><strong>Methods: </strong>This retrospective, nationwide, register-based study evaluated all patients who were dispensed oral formulation stimulants (Anatomical Therapeutic Chemical [ATC] codes: N06BA01, N06BA02, N06BA04, N06BA12) identified in the Swedish Prescribed Drug Register. Treatment episodes were constructed based on drug dispensation data, and treatment adherence was calculated for each treatment episode using a Proportion of Days Covered approach with a modified one-pill-a-day method.</p><p><strong>Results: </strong>Between 2015 and 2020, 158,413 treatment episodes were recorded in 128,366 patients, corresponding to a median 1.23 treatment episodes per patient. The majority of treatment episodes involved methylphenidate (64.0%), followed by lisdexamfetamine (32.2%), dexamfetamine (3.0%), and amphetamine (0.8%). Overall treatment adherence was high (78.2%), and was similar for patients receiving methylphenidate, lisdexamfetamine, and dexamfetamine. The proportion of patients with ≥80% medication adherence was high (69.3%-71.8%) for adults aged ≥25 years, but was low for adolescents aged 12 to 17 years (49.7%-52.4%).</p><p><strong>Conclusions: </strong>The overall rates of treatment adherence are high for children and adults receiving ADHD medication in Sweden. We observed lower adherence among adolescents, which warrants further study.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251406760"},"PeriodicalIF":2.2,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146010572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-18DOI: 10.1177/10870547251408120
Ruth Netzer Turgeman, Yehuda Pollak
Objective: This study aims to investigate the complex relation between adult ADHD symptoms, procrastination, and mediating factors, in light of leading procrastination theories: the Temporal Motivation Theory (TMT), emotion regulation, and a General Architecture for Modeling the Dynamics of Goal-Directed Motivation and Decision-Making - the GOAL architecture.
Method: The study was preregistered. A survey was conducted with 640 adults recruited online to examine the associations between ADHD symptoms, procrastination, and seven mediating factors. Participants completed measures assessing ADHD symptoms, procrastination tendencies, emotion regulation, motivation, and goal-related behaviors. Structural equation modeling (SEM) was used to test the direct and indirect pathways among the variables.
Results: A positive association was revealed between ADHD inattention symptoms and procrastination tendencies. The mediating factors that significantly contributed to this relations were sensitivity to delay, perceived low value of the task, and flexible goal adjustment. While ADHD inattention symptoms was associated with all seven variables, three variables directly contributed to increased procrastination behavior, thus explaining the link between inattention symptoms and procrastination.
Conclusions: The study highlights the relations between procrastination and adult ADHD symptoms and underscores the need to address mediating factors in intervention strategies. Understanding these mechanisms is essential for developing targeted interventions to improve functional outcomes for individuals with ADHD.
{"title":"What Are You Waiting For?! Roles of Motivation, Goal Orientation, and Emotion Regulation in Explaining the Link Between ADHD and Procrastination.","authors":"Ruth Netzer Turgeman, Yehuda Pollak","doi":"10.1177/10870547251408120","DOIUrl":"https://doi.org/10.1177/10870547251408120","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the complex relation between adult ADHD symptoms, procrastination, and mediating factors, in light of leading procrastination theories: the Temporal Motivation Theory (TMT), emotion regulation, and a General Architecture for Modeling the Dynamics of Goal-Directed Motivation and Decision-Making - the GOAL architecture.</p><p><strong>Method: </strong>The study was preregistered. A survey was conducted with 640 adults recruited online to examine the associations between ADHD symptoms, procrastination, and seven mediating factors. Participants completed measures assessing ADHD symptoms, procrastination tendencies, emotion regulation, motivation, and goal-related behaviors. Structural equation modeling (SEM) was used to test the direct and indirect pathways among the variables.</p><p><strong>Results: </strong>A positive association was revealed between ADHD inattention symptoms and procrastination tendencies. The mediating factors that significantly contributed to this relations were sensitivity to delay, perceived low value of the task, and flexible goal adjustment. While ADHD inattention symptoms was associated with all seven variables, three variables directly contributed to increased procrastination behavior, thus explaining the link between inattention symptoms and procrastination.</p><p><strong>Conclusions: </strong>The study highlights the relations between procrastination and adult ADHD symptoms and underscores the need to address mediating factors in intervention strategies. Understanding these mechanisms is essential for developing targeted interventions to improve functional outcomes for individuals with ADHD.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"10870547251408120"},"PeriodicalIF":2.2,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}