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Differential diagnosis between recurrent disc herniation and granulation tissue after lumbar disc herniation Surgery: Qualitative analysis on MRI scans 腰椎间盘突出症手术后复发性椎间盘突出症与肉芽组织的鉴别诊断:磁共振成像扫描的定性分析
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-16 DOI: 10.1016/j.jocn.2024.110870
Ziya Asan , Halime Tozak Yildiz

Background

Recurrence of disc herniation is a prevalent late-term complication among patients surgically treated for lumbar disc herniation. Differential diagnosis between recurrent disc herniation and granulation tissue can be achieved through signal intensity measurements on T2-weighted MRI examinations. This study aims to examine cases operated on for recurrence of lumbar disc herniation, assessing those presenting with either disc recurrence or granulation tissue. The objective is to demonstrate that differential diagnosis can be facilitated through signal intensity value measurements and radiological findings in MRI examinations of patients with disc herniation recurrence and granulation tissue.

Methods

Analysis involved reviewing lumbar MRI T2 sequences of patients operated on with a presumptive diagnosis of lumbar disc herniation recurrence. Mean T2 signal intensity values in preoperative MRI images of cases with disc herniation recurrence and granulation tissue were examined and recorded on the Picture Archiving and Communication System. Mean T2 signal intensity values of recurrent disc herniation and granulation tissue were then compared.

Results

Among the patients who underwent surgery, disc herniation recurrence was observed in 135 cases, while granulation tissue was found in 12 patients (8.89 %). The preopreative mean T2 signal intensity value for disc herniation was recorded as 54.82 ± 2.42, whereas the mean T2 signal intensity value for granulation tissue was 205.96 ± 5.62.

Conclusions

T2 sequences in MRI examinations offer the clearest evaluation of disc herniations. Mean T2 signal intensity value measurements conducted on the PACS system can aid in differentiating between recurrent disc herniation and granulation tissue. These findings serve to inform surgical protocols during the preoperative phase.
背景椎间盘突出症复发是腰椎间盘突出症手术治疗患者普遍存在的晚期并发症。通过T2加权磁共振成像检查的信号强度测量可对复发的椎间盘突出症和肉芽组织进行鉴别诊断。本研究旨在检查因腰椎间盘突出症复发而接受手术的病例,评估出现椎间盘复发或肉芽组织的病例。目的是证明通过对椎间盘突出复发和肉芽组织患者的磁共振成像检查中的信号强度值测量和放射学发现,可以帮助进行鉴别诊断。方法分析包括对推测诊断为腰椎间盘突出复发的手术患者的腰椎磁共振成像 T2 序列进行复查。对腰椎间盘突出症复发和肉芽组织病例的术前 MRI 图像的平均 T2 信号强度值进行检查,并记录在图像存档和通信系统中。结果在接受手术的患者中,135 例观察到椎间盘突出复发,12 例发现肉芽组织(8.89%)。手术前椎间盘突出症的平均 T2 信号强度值为(54.82 ± 2.42),而肉芽组织的平均 T2 信号强度值为(205.96 ± 5.62)。在 PACS 系统上进行的平均 T2 信号强度值测量有助于区分复发性椎间盘突出症和肉芽组织。这些发现可为术前阶段的手术方案提供参考。
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引用次数: 0
Daytime versus out-of-hours surgery for Chronic Subdural Hematoma 慢性硬膜下血肿日间手术和非工作时间手术的比较
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-15 DOI: 10.1016/j.jocn.2024.110863
Conor S. Gillespie , Christopher Quelch , Kisanet Medhanie , Sruthi Ranganathan , Rajeevlochan Ravi , Munashe Veremu , William H. Cook , Prabhjot S. Malhotra , Oliver D. Mowforth , Daniel P. Brown
Chronic Subdural Hematoma (CSDH) is one of the most common neurosurgical pathologies. Due to an elderly demographic with increasing co-morbidities, surgery is often deferred out of hours. This may reduce complication risk, but increases length of stay and may compromise patient care due to delayed surgery. We performed a retrospective service evaluation of CSDH patients undergoing primary surgery (September 2021–September 2023) at a tertiary neurosciences centre. Out of hours (OOH) was defined as an operation start time outside 8 am–8 pm. Primary outcome was recurrence requiring repeat surgery. Secondary outcomes included complications, thromboembolic events (DVT/PE), length of stay, and in hospital mortality. Differences were assessed using Chi-Squared tests and Student’s t-tests. A total of 263 patients were included (200 (76.0 %) male, mean age 75.0 ± 11.3 yrs). Median time from admission to surgery was 37 h (IQR 14–71.5 h). In total, 49.8 % (131/263) of operations took place OOH. There were no significant differences in baseline characteristics between the two groups. At a median follow-up of 9.2 months (IQR 4.8–13.2 months) there was no difference in recurrence rates between OOH and in hours groups (14.5 % vs. 17.7 %, p = 0.483). There was no difference in complication rates (13.7 % vs 16.2 %, p = 0.585), thromboembolic events (3.8 % vs 3.1 %, p = 0.743), length of stay (mean 15.9 vs 15.2 days, p = 0.787), or in-hospital mortality (2.3 % vs 3.1 %, p = 0.483). OOH surgery for CSDH surgery is safe, does not appear to affect complications, recurrence, or mortality, and should be considered in appropriately selected cases.
慢性硬膜下血肿(CSDH)是最常见的神经外科病理之一。由于老年人群合并疾病越来越多,手术往往被推迟到非工作时间进行。这可能会降低并发症风险,但会延长住院时间,并可能因手术延迟而影响患者护理。我们对一家三级神经科学中心接受初级手术的 CSDH 患者进行了回顾性服务评估(2021 年 9 月至 2023 年 9 月)。非工作时间(OOH)是指手术开始时间在上午 8 点至晚上 8 点之外。主要结果是需要再次手术的复发率。次要结果包括并发症、血栓栓塞事件(DVT/PE)、住院时间和住院死亡率。差异采用秩方检验和学生 t 检验进行评估。共纳入了 263 名患者(200 名(76.0%)男性,平均年龄为 75.0 ± 11.3 岁)。从入院到手术的中位时间为 37 小时(IQR 14-71.5 小时)。总共有 49.8% 的手术(131/263)是在户外进行的。两组患者的基线特征无明显差异。中位随访时间为9.2个月(IQR为4.8-13.2个月),手术组与非住院组的复发率无差异(14.5% vs. 17.7%,P = 0.483)。并发症发生率(13.7% 对 16.2%,P = 0.585)、血栓栓塞事件(3.8% 对 3.1%,P = 0.743)、住院时间(平均 15.9 天对 15.2 天,P = 0.787)或院内死亡率(2.3% 对 3.1%,P = 0.483)均无差异。CSDH手术的体外手术是安全的,似乎不会影响并发症、复发或死亡率,应在适当选择的病例中予以考虑。
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引用次数: 0
Dorsal arachnoid web: A neurological condition with significant gaps in clinical and translational evidence. 背侧蛛网膜:一种在临床和转化证据方面存在重大差距的神经系统疾病。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-05 DOI: 10.1016/j.jocn.2024.110860
Johana Patricia Galván-Barrios, Jessica Manosalva-Sandoval
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引用次数: 0
Enhancing exposure in endoscopic endonasal resection of Craniopharyngioma: Sellar floor dural incision technique 加强颅咽管瘤内窥镜鼻内切除术的暴露:ellar底硬脑膜切口技术。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-05 DOI: 10.1016/j.jocn.2024.110855
Raywat Noiphithak , Juan C. Yanez-Siller
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引用次数: 0
Letter to the editor: Comment on "Global neurotrauma: A systematic review and summary of the current state of registries around the world". 致编辑的信评论 "全球神经创伤:全球神经创伤:全球登记现状的系统回顾与总结 "的评论。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-05 DOI: 10.1016/j.jocn.2024.110856
Rizky Andana Pohan, M Ramli, Adi Atmoko, Sa'dun Akbar, Erfan Ramadhani, Rikas Saputra, Ririn Dwi Astuti
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引用次数: 0
Comment on: "Decreased timing to vasospasm prophylaxis improves outcomes among patients with aneurysmal subarachnoid hemorrhage (aSAH) on prehospital CCBs, ARBs, or ACE-inhibitors". 评论"减少预防血管痉挛的时机可改善院前服用氯苯类药物、血管紧张素缓释剂或血管紧张素转换酶抑制剂的动脉瘤性蛛网膜下腔出血(aSAH)患者的预后"。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-04 DOI: 10.1016/j.jocn.2024.110859
Gurdeep Gambhir
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引用次数: 0
Worm-like necrotic inflammatory substance in Jackson-Pratt drain after spinal fusion 脊柱融合术后杰克逊-普拉特引流管中的蠕虫状坏死炎性物质。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-04 DOI: 10.1016/j.jocn.2024.110861
Meagan Paige Aladin , Jose Mantilla Arango , Eddie Louie , Themistocles Protopsaltis , Ariane Lewis
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引用次数: 0
Endoscopic reconstruction to primary empty sella: “7 E” technique 内窥镜重建原发性空蝶鞍:"7 E "技术
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-04 DOI: 10.1016/j.jocn.2024.110854
Juan F. Villalonga, Ernesto Ardisana, Agustín Martínez-Font, José I. Pailler, Álvaro Campero
We present the seven “E” technique step by step for the reconstruction of the empty sella with an illustrative case.
我们通过一个示例,逐步介绍了重建空蝶鞍的七 "E "技术。
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引用次数: 0
Clinical profile and outcomes in Tolosa-Hunt Syndrome; a systematic review 托洛萨-亨特综合征的临床概况和疗效;系统综述。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-03 DOI: 10.1016/j.jocn.2024.110858
H. Shafeeq Ahmed , Deepak B. Shivananda , Sneha Reddy Pulkurthi , Akhil Fravis Dias , Prachi Parinita Sahoo

Introduction

Tolosa-Hunt Syndrome (THS) stands as a rare headache disorder distinguished by painful ophthalmoplegia, accompanied by headaches and cranial nerve palsies. The syndrome was initially identified by Eduardo Tolosa in Spain in 1954. He observed granulomatous inflammation surrounding a carotid siphon in a patient with an intracavernous carotid aneurysm. The objective of this systematic review is to consolidate and summarize existing studies on THS, providing a comprehensive evaluation of its clinical findings and outcomes.

Methods

This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) checklist. Systematic searches were conducted on PubMed and Scopus databases to identify literature examining the sociodemographics, clinical findings, cranial nerve palsies, laboratory and radiological data, treatment, and outcomes of THS. The study followed a pre-established protocol registered on the PROSPERO database (ID: CRD42023494249).

Results

Out of 1115 studies screened, 11 met the predefined inclusion and exclusion criteria. The studies predominantly focused on Asian populations, emphasizing unilateral orbital headaches as a common clinical feature. Ophthalmological findings, including restriction of eye movements, diplopia, ptosis, and vision loss, were prevalent. Studies also highlighted some cases presenting atypically without ophthalmoplegia but with acute vision changes. Oculomotor nerve palsy, followed by abducens and trochlear nerve palsies, were the most frequently reported. Laboratory investigations across the studies often showed normal cerebrospinal fluid findings and varying levels of inflammatory markers like ESR and CRP. Inflammation of the cavernous sinus and orbital apex was noted most frequently. Treatment strategies were consistent across the studies, with steroids (both IV and oral) being the mainstay treatment for managing THS. Despite the use of steroids, the studies reported varied outcomes in terms of pain relief and recovery from cranial nerve deficits, with some cases showing rapid improvement while others had prolonged or incomplete recovery. Other immunosuppressants and steroid sparing agents are used with varying levels of success. Recurrence rates ranged from 9% to 71% across studies.

Conclusion

This review discusses the varied constellation of symptoms associated with THS, with headaches and cranial nerve findings being consistently observed. High and low doses, as well as both intravenous and oral steroids, have proven to be effective in managing THS. Overall, the prognosis appears favorable, with a limited number of cases showing recurrence.
简介托洛萨-亨特综合征(Tolosa-Hunt Syndrome,THS)是一种罕见的头痛疾病,主要表现为眼球疼痛,并伴有头痛和颅神经麻痹。该综合征最初由爱德华多-托罗萨(Eduardo Tolosa)于 1954 年在西班牙发现。他在一名颈内动脉瘤患者的颈动脉虹吸管周围观察到肉芽肿性炎症。本系统性综述旨在整合和总结现有的 THS 研究,对其临床发现和结果进行全面评估:本综述遵循系统综述和荟萃分析首选报告项目(PRISMA)清单。在 PubMed 和 Scopus 数据库中进行了系统检索,以确定研究 THS 的社会人口统计学、临床发现、颅神经麻痹、实验室和放射学数据、治疗和结果的文献。研究按照事先制定的方案在 PROSPERO 数据库(ID:CRD42023494249)中注册:在筛选出的 1115 项研究中,有 11 项符合预定义的纳入和排除标准。这些研究主要针对亚洲人群,强调单侧眼眶头痛是常见的临床特征。眼科检查结果包括眼球运动受限、复视、上睑下垂和视力减退等。研究还强调了一些没有眼肌麻痹但出现急性视力改变的非典型病例。眼运动神经麻痹是最常见的病例,其次是外展神经和耳蜗神经麻痹。各项研究中的实验室检查通常显示脑脊液结果正常,而 ESR 和 CRP 等炎症标志物水平不一。海绵窦和眶顶的炎症最为常见。各项研究的治疗策略一致,类固醇(静脉注射和口服)是控制 THS 的主要治疗方法。尽管使用了类固醇,但研究报告在疼痛缓解和颅神经功能缺损恢复方面的结果不尽相同,有些病例迅速好转,而有些病例则恢复时间较长或恢复不完全。其他免疫抑制剂和类固醇稀释剂的使用也取得了不同程度的成功。各项研究的复发率从 9% 到 71% 不等:这篇综述讨论了与 THS 相关的各种症状,其中头痛和颅神经症状始终存在。事实证明,大剂量和小剂量以及静脉注射和口服类固醇都能有效控制 THS。总体看来,预后良好,只有少数病例出现复发。
{"title":"Clinical profile and outcomes in Tolosa-Hunt Syndrome; a systematic review","authors":"H. Shafeeq Ahmed ,&nbsp;Deepak B. Shivananda ,&nbsp;Sneha Reddy Pulkurthi ,&nbsp;Akhil Fravis Dias ,&nbsp;Prachi Parinita Sahoo","doi":"10.1016/j.jocn.2024.110858","DOIUrl":"10.1016/j.jocn.2024.110858","url":null,"abstract":"<div><h3>Introduction</h3><div>Tolosa-Hunt Syndrome (THS) stands as a rare headache disorder distinguished by painful ophthalmoplegia, accompanied by headaches and cranial nerve palsies. The syndrome was initially identified by Eduardo Tolosa in Spain in 1954. He observed granulomatous inflammation surrounding a carotid siphon in a patient with an intracavernous carotid aneurysm. The objective of this systematic review is to consolidate and summarize existing studies on THS, providing a comprehensive evaluation of its clinical findings and outcomes.</div></div><div><h3>Methods</h3><div>This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) checklist. Systematic searches were conducted on PubMed and Scopus databases to identify literature examining the sociodemographics, clinical findings, cranial nerve palsies, laboratory and radiological data, treatment, and outcomes of THS. The study followed a pre-established protocol registered on the PROSPERO database (ID: CRD42023494249).</div></div><div><h3>Results</h3><div>Out of 1115 studies screened, 11 met the predefined inclusion and exclusion criteria. The studies predominantly focused on Asian populations, emphasizing unilateral orbital headaches as a common clinical feature. Ophthalmological findings, including restriction of eye movements, diplopia, ptosis, and vision loss, were prevalent. Studies also highlighted some cases presenting atypically without ophthalmoplegia but with acute vision changes. Oculomotor nerve palsy, followed by abducens and trochlear nerve palsies, were the most frequently reported. Laboratory investigations across the studies often showed normal cerebrospinal fluid findings and varying levels of inflammatory markers like ESR and CRP. Inflammation of the cavernous sinus and orbital apex was noted most frequently. Treatment strategies were consistent across the studies, with steroids (both IV and oral) being the mainstay treatment for managing THS. Despite the use of steroids, the studies reported varied outcomes in terms of pain relief and recovery from cranial nerve deficits, with some cases showing rapid improvement while others had prolonged or incomplete recovery. Other immunosuppressants and steroid sparing agents are used with varying levels of success. Recurrence rates ranged from 9% to 71% across studies.</div></div><div><h3>Conclusion</h3><div>This review discusses the varied constellation of symptoms associated with THS, with headaches and cranial nerve findings being consistently observed. High and low doses, as well as both intravenous and oral steroids, have proven to be effective in managing THS. Overall, the prognosis appears favorable, with a limited number of cases showing recurrence.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"129 ","pages":"Article 110858"},"PeriodicalIF":1.9,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term course of gastrostomy nutritional management in patients with Duchenne muscular dystrophy: A retrospective cohort study 杜兴氏肌肉萎缩症患者胃造口术营养管理的长期疗程:回顾性队列研究。
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-10-02 DOI: 10.1016/j.jocn.2024.110857
Yuki Takanarita , Yuichi Okata , Hiroyuki Awano , Ryosuke Bo , Yuko Bitoh
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease that commonly requires gastrostomy due to dysphagia. This study aimed to investigate the proportion of patients with DMD requiring gastrostomy and to assess the timing and outcomes of gastrostomy in patients with DMD to optimize perioperative care and improve long-term management. We conducted a retrospective cohort study by reviewing the medical records of patients with DMD treated between March 1991 and November 2023 at Kobe University Hospital. To identify risk factors for gastrostomy, Fisher’s two-tailed test and logistic analysis were used to compare the gastrostomy (group G) and comparison group without gastrostomy (group C) groups. We identified patients >18 years with DMD. We excluded those without medical records from the last decade and those on nasogastric tube feeding. Among the 135 eligible patients, five (median age, 23 years) underwent percutaneous endoscopic gastrostomy (PEG; uptake rate, 3.7 %), and their data were analyzed for perioperative outcomes. Complications included ventilatory disturbances, aspiration pneumonia, and hemorrhagic shock. Two patients experienced significant postoperative complications, underscoring the high-risk nature of PEG in this population. Participants’ postoperative weight changes varied significantly. The presence or absence of ventilatory management, cardiomyopathy treatment, scoliosis, and steroid treatment were examined as risk factors between groups G and C, but no significant differences were observed. This study highlights low gastrostomy usage among patients with DMD, with varying outcomes. Meticulous planning and early consideration of gastrostomy are crucial to enhance the quality of life and nutritional outcomes in these patients.
杜兴氏肌营养不良症(DMD)是一种进行性神经肌肉疾病,通常因吞咽困难而需要进行胃造瘘术。本研究旨在调查需要进行胃造口术的 DMD 患者比例,并评估 DMD 患者进行胃造口术的时机和结果,以优化围手术期护理并改善长期管理。我们通过回顾 1991 年 3 月至 2023 年 11 月期间在神户大学医院接受治疗的 DMD 患者的医疗记录,开展了一项回顾性队列研究。为了确定胃造口术的风险因素,我们采用费雪双尾检验和逻辑分析法比较了胃造口术组(G 组)和无胃造口术对比组(C 组)。我们确定了年龄大于 18 岁的 DMD 患者。我们排除了没有过去十年医疗记录的患者和使用鼻胃管喂养的患者。在 135 名符合条件的患者中,有 5 人(中位年龄为 23 岁)接受了经皮内镜胃造瘘术(PEG;接受率为 3.7%),我们对他们的数据进行了围手术期结果分析。并发症包括通气障碍、吸入性肺炎和失血性休克。两名患者出现了严重的术后并发症,凸显了 PEG 在这一人群中的高风险性。参与者的术后体重变化差异很大。作为 G 组和 C 组之间的风险因素,对是否存在通气管理、心肌病治疗、脊柱侧弯和类固醇治疗进行了研究,但未观察到明显差异。这项研究表明,DMD 患者使用胃造瘘术的比例较低,但结果却各不相同。为提高这些患者的生活质量和营养状况,精心策划和及早考虑胃造口术至关重要。
{"title":"Long-term course of gastrostomy nutritional management in patients with Duchenne muscular dystrophy: A retrospective cohort study","authors":"Yuki Takanarita ,&nbsp;Yuichi Okata ,&nbsp;Hiroyuki Awano ,&nbsp;Ryosuke Bo ,&nbsp;Yuko Bitoh","doi":"10.1016/j.jocn.2024.110857","DOIUrl":"10.1016/j.jocn.2024.110857","url":null,"abstract":"<div><div>Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease that commonly requires gastrostomy due to dysphagia. This study aimed to investigate the proportion of patients with DMD requiring gastrostomy and to assess the timing and outcomes of gastrostomy in patients with DMD to optimize perioperative care and improve long-term management. We conducted a retrospective cohort study by reviewing the medical records of patients with DMD treated between March 1991 and November 2023 at Kobe University Hospital. To identify risk factors for gastrostomy, Fisher’s two-tailed test and logistic analysis were used to compare the gastrostomy (group G) and comparison group without gastrostomy (group C) groups. We identified patients &gt;18 years with DMD. We excluded those without medical records from the last decade and those on nasogastric tube feeding. Among the 135 eligible patients, five (median age, 23 years) underwent percutaneous endoscopic gastrostomy (PEG; uptake rate, 3.7 %), and their data were analyzed for perioperative outcomes. Complications included ventilatory disturbances, aspiration pneumonia, and hemorrhagic shock. Two patients experienced significant postoperative complications, underscoring the high-risk nature of PEG in this population. Participants’ postoperative weight changes varied significantly. The presence or absence of ventilatory management, cardiomyopathy treatment, scoliosis, and steroid treatment were examined as risk factors between groups G and C, but no significant differences were observed. This study highlights low gastrostomy usage among patients with DMD, with varying outcomes. Meticulous planning and early consideration of gastrostomy are crucial to enhance the quality of life and nutritional outcomes in these patients.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"129 ","pages":"Article 110857"},"PeriodicalIF":1.9,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Clinical Neuroscience
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