Pub Date : 2023-01-01DOI: 10.4236/jcdsa.2023.131001
H. Thong, Po-jen Lin, Chieh-Chen Huang
{"title":"A Comprehensive Review of Long-Term Safety and Effectiveness of FACILLE Modified Sodium Hyaluronate Gel for Injection over 3 Years","authors":"H. Thong, Po-jen Lin, Chieh-Chen Huang","doi":"10.4236/jcdsa.2023.131001","DOIUrl":"https://doi.org/10.4236/jcdsa.2023.131001","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83902657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.124016
H. Polonini, Anton Ameneiro-Alvarez, C. Zander
{"title":"Safety Assessment of a Novel Topical Vehicle for Personalized Treatments in Acne","authors":"H. Polonini, Anton Ameneiro-Alvarez, C. Zander","doi":"10.4236/jcdsa.2022.124016","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.124016","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80526854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.124015
Salah Hassan Ibrahim, Mengqi Guan, Shanshan Li
{"title":"Systemic Immune Inflammatory Index Is Associated with Pustular Psoriasis: A Single Center Retrospective Study","authors":"Salah Hassan Ibrahim, Mengqi Guan, Shanshan Li","doi":"10.4236/jcdsa.2022.124015","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.124015","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"7 10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81698947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Traditional treatment of axillary odour is the surgical removal of skin and subcutaneous tissue along the edge of the axillary hair in a fusiform shape, which requires the restriction of upper limb activity, has large scars and a high recurrence rate. Minimally invasive methods have developed in recent years. The subcutaneous trimming method with small incision reduces the incision compared to traditional incision, but still requires skin incision, which does not achieve true, minimally invasive treatment. Simple negative pressure suction is difficult to destroy the sweat glands and sebaceous glands in the dermis layer. Thus, we hypothesized that combination of three minimally invasive methods might be more effective. Objective: To ex-plore the clinical effect of combined treatment of axillary osmidrosis by three minimally invasive methods of microwave, scraping & suction and scratching. Methods: From October 2015 to October 2020, 80 patients with underarm odor were enrolled and lacal swelling anesthetic was applied. Microwave was used to treat sweat glands and sebaceous glands in the dermis following the pores. The curettage-aspiration was used to scrape and suck the apocrine sweat glands in the subcutaneous fat layer and the junction between (2.50%) with skin necrosis on 3 sides, 1 case (1.25%) with uneven skin on 2 sides, 1 case (1.25%) with axillary abscess on 2 sides, and 1 case (1.25%) with keloids on 2 sides. Conclusion: The combination of three minimally invasive methods of microwave, scraping & suction and scratching to treat underarm odor is simple operation, has high cure rate, quick postoperative recovery, and few complications. It is an effective method for minimally invasive and thorough treatment of underarm odor in clinic.
{"title":"The Clinical Evaluation of Minimally Invasive Treatment for Axillary Osmidrosis","authors":"Yongxiang Wang, Qi Li, Cui-e Wei, Xinyan Xu, Shu-mei Ma, Xiaojiao Yan, Fei Xie, Junting Ma","doi":"10.4236/jcdsa.2022.121002","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.121002","url":null,"abstract":"Background: Traditional treatment of axillary odour is the surgical removal of skin and subcutaneous tissue along the edge of the axillary hair in a fusiform shape, which requires the restriction of upper limb activity, has large scars and a high recurrence rate. Minimally invasive methods have developed in recent years. The subcutaneous trimming method with small incision reduces the incision compared to traditional incision, but still requires skin incision, which does not achieve true, minimally invasive treatment. Simple negative pressure suction is difficult to destroy the sweat glands and sebaceous glands in the dermis layer. Thus, we hypothesized that combination of three minimally invasive methods might be more effective. Objective: To ex-plore the clinical effect of combined treatment of axillary osmidrosis by three minimally invasive methods of microwave, scraping & suction and scratching. Methods: From October 2015 to October 2020, 80 patients with underarm odor were enrolled and lacal swelling anesthetic was applied. Microwave was used to treat sweat glands and sebaceous glands in the dermis following the pores. The curettage-aspiration was used to scrape and suck the apocrine sweat glands in the subcutaneous fat layer and the junction between (2.50%) with skin necrosis on 3 sides, 1 case (1.25%) with uneven skin on 2 sides, 1 case (1.25%) with axillary abscess on 2 sides, and 1 case (1.25%) with keloids on 2 sides. Conclusion: The combination of three minimally invasive methods of microwave, scraping & suction and scratching to treat underarm odor is simple operation, has high cure rate, quick postoperative recovery, and few complications. It is an effective method for minimally invasive and thorough treatment of underarm odor in clinic.","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78579181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.123012
Waqas S. Abdulwahhab, Fatima M. Al Qaydi
{"title":"Urticarial Bullous Pemphigoid: A New Case Report","authors":"Waqas S. Abdulwahhab, Fatima M. Al Qaydi","doi":"10.4236/jcdsa.2022.123012","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.123012","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82143858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.121001
A. Aioi, R. Muromoto, T. Matsuda
Background: It is important to maintain skin homeostasis for cosmetic and medical reasons. Many ceramide-related ingredients and cosmetics have been developed to improve the skin barrier function and skin hydration. Similar to extracellular lipids, the cornified envelope, which is a structure formed beneath the plasma membrane, contributes to the skin barrier function as a scaffold for extracellular lipids. Therefore, in this study, we focused on transglutaminase 1 (TGM1) which is the key enzyme for formation of the cornified envelope Objective: The objectives of this study were to identify compounds that could upregulate the expression of TGM1 and evaluate their underlying action mechanisms. Methods: Expression of the transient receptor potential channel vanilloid subfamily member 4 (TRPV4) at the mRNA and protein levels was estimated by PCR and western blotting. Effects of baicalein and Salvia officinalis (SO) extract on TGM1 mRNA expression were meas-ured by PCR. The involvement of TRPV4 in TGM1 mRNA expression was evaluated by the inhibition and silencing of TRPV4. Results: TRPV4 was expressed in both basal cell-like HaCaT cells and suprabasal cell-like HaCaT cells. Baicalein and SO extract upregulated TGM1 mRNA expression in basal cell-like HaCaT cells. However, inhibition and silencing of TRPV4 abrogated the effects of baicalein and SO extract. Conclusion: Baicalein and SO extract upregulated the expression of TGM1 mRNA via the activation of TRPV4, suggesting that it may improve the skin barrier function by enhancing cornified envelope formation.
{"title":"Baicalein and <i>Salvia officinalis</i> Extract Upregulate Transglutaminase 1 mRNA Expression via the Activation of Transient Receptor Potential Channel V4","authors":"A. Aioi, R. Muromoto, T. Matsuda","doi":"10.4236/jcdsa.2022.121001","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.121001","url":null,"abstract":"Background: It is important to maintain skin homeostasis for cosmetic and medical reasons. Many ceramide-related ingredients and cosmetics have been developed to improve the skin barrier function and skin hydration. Similar to extracellular lipids, the cornified envelope, which is a structure formed beneath the plasma membrane, contributes to the skin barrier function as a scaffold for extracellular lipids. Therefore, in this study, we focused on transglutaminase 1 (TGM1) which is the key enzyme for formation of the cornified envelope Objective: The objectives of this study were to identify compounds that could upregulate the expression of TGM1 and evaluate their underlying action mechanisms. Methods: Expression of the transient receptor potential channel vanilloid subfamily member 4 (TRPV4) at the mRNA and protein levels was estimated by PCR and western blotting. Effects of baicalein and Salvia officinalis (SO) extract on TGM1 mRNA expression were meas-ured by PCR. The involvement of TRPV4 in TGM1 mRNA expression was evaluated by the inhibition and silencing of TRPV4. Results: TRPV4 was expressed in both basal cell-like HaCaT cells and suprabasal cell-like HaCaT cells. Baicalein and SO extract upregulated TGM1 mRNA expression in basal cell-like HaCaT cells. However, inhibition and silencing of TRPV4 abrogated the effects of baicalein and SO extract. Conclusion: Baicalein and SO extract upregulated the expression of TGM1 mRNA via the activation of TRPV4, suggesting that it may improve the skin barrier function by enhancing cornified envelope formation.","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88013402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.121005
F. Fanian, Pauline Meunier, Diana Bumbea, K. Dahel, P. Humbert
{"title":"Efficacy and Safety of a Botanical Topical Serum on Male and Female Androgenetic Alopecia","authors":"F. Fanian, Pauline Meunier, Diana Bumbea, K. Dahel, P. Humbert","doi":"10.4236/jcdsa.2022.121005","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.121005","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88429932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitamin C (ascorbic acid) plays an important role in maintaining skin health, and topical vitamin C supplementation can counteract oxidative stress induced by UVA, due to excellent reducibility. To clarify the efficacy of vitamin C on the skin in the carrier of lotion, we studied its permeability, irritation and anti-aging effect in vitro and in vivo, using Franz cell system, cell model and clinical test. The permeability test showed that vitamin C with 10%, 15%, 20% and 25% mass ratio could effectively penetrate skin. The 20% of vitamin C lotion (VCL-20%) had the highest efficiency of transdermal penetration and the diffusion percentage reached 84.707% after 24 h. Besides, the permeation quantity of VCL-20% was 1.43 times that of the control group. Irritation test showed that the cytotoxicity of vitamin C lotion was low. And no allergic reaction happened in the occlusive patch test. Compared with the control group, using vitamin C lotion for 28 days could significantly improve subjects’ skin gloss of 10.53% and improve skin color, enhance facial skin elasticity and tightness of 9.20% and reduce wrinkle area of 12.27% (p < 0.05).
{"title":"Study on the Efficacy of Vitamin C Lotion on Skin: Permeable and Anti-Aging","authors":"Mengping Wang, Wangwang Lu, Xin-ru Ge, Yuan Lu, Xiwen Jia, Huiming Li, Qiaoyuan Liu","doi":"10.4236/jcdsa.2022.121006","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.121006","url":null,"abstract":"Vitamin C (ascorbic acid) plays an important role in maintaining skin health, and topical vitamin C supplementation can counteract oxidative stress induced by UVA, due to excellent reducibility. To clarify the efficacy of vitamin C on the skin in the carrier of lotion, we studied its permeability, irritation and anti-aging effect in vitro and in vivo, using Franz cell system, cell model and clinical test. The permeability test showed that vitamin C with 10%, 15%, 20% and 25% mass ratio could effectively penetrate skin. The 20% of vitamin C lotion (VCL-20%) had the highest efficiency of transdermal penetration and the diffusion percentage reached 84.707% after 24 h. Besides, the permeation quantity of VCL-20% was 1.43 times that of the control group. Irritation test showed that the cytotoxicity of vitamin C lotion was low. And no allergic reaction happened in the occlusive patch test. Compared with the control group, using vitamin C lotion for 28 days could significantly improve subjects’ skin gloss of 10.53% and improve skin color, enhance facial skin elasticity and tightness of 9.20% and reduce wrinkle area of 12.27% (p < 0.05).","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77663881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.123011
A. Aioi, R. Muromoto, J. Kashiwakura, S. Mogami, Megumi Nishikawa, Shigeyuki Ogawa, T. Matsuda
{"title":"Porcine Placenta Extract Enhances Ceramide Synthase 3 Expression through the PPAR<i>δ</i>/ILK/Akt/mTOR/STAT3 Pathway","authors":"A. Aioi, R. Muromoto, J. Kashiwakura, S. Mogami, Megumi Nishikawa, Shigeyuki Ogawa, T. Matsuda","doi":"10.4236/jcdsa.2022.123011","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.123011","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87173874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.4236/jcdsa.2022.124013
R. Lubart, A. Lipovsky
{"title":"Immediate and Long Term Clinical Benefits of a Novel Topical Micronized Collagen Face Cream","authors":"R. Lubart, A. Lipovsky","doi":"10.4236/jcdsa.2022.124013","DOIUrl":"https://doi.org/10.4236/jcdsa.2022.124013","url":null,"abstract":"","PeriodicalId":15654,"journal":{"name":"Journal of Cosmetics, Dermatological Sciences and Applications","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75517174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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