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Paternal Involvement in Childcare and Housework and Mothers' Spanking Behavior: The Japanese Longitudinal Survey of Newborns in the 21st Century. 父亲参与育儿和家务劳动与母亲打屁股行为:21 世纪日本新生儿纵向调查。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-05 Epub Date: 2024-10-31 DOI: 10.2188/jea.JE20230270
Mako Nagayoshi, Yuko Kachi, Tsuguhiko Kato, Manami Ochi, Yuichi Ichinose, Takayuki Kondo, Kenji Takehara

Background: No previous study reported an association of paternal involvement in childcare and housework with maternal physical punishment.

Methods: Using data from the Japanese Longitudinal Survey of Newborns in the 21st century (N = 38,554), we analyzed responses about fathers' involvement in childcare and housework at 6 months and mothers' spanking of children at 3.5 years. Fathers' involvement in childcare and housework was scored and categorized into quartiles. Spanking frequency was asked in the "often", "sometimes", or "not at all" categories. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the mothers' often spanking children were computed for the fathers' involvement in childcare and housework. We also stratified the association by fathers' working hours (40-49, 50-59, or ≥60 hours/week).

Results: Among the 16,373 respondents, the proportion of mothers who often spanked their children was 4.8%. Compared with the lowest quartile, a higher frequency of paternal involvement in housework was associated with a lower risk of spanking children (Ptrend = 0.001). Adjustment for covariates attenuated the association, but significant association was observed in the 3rd quartile of paternal involvement in housework (OR 0.77; 95% CI, 0.62-0.96). When the fathers worked fewer than 50 hours a week, a significant negative association was observed between the fathers' frequency of childcare and the likeliness of the mothers' spanking their children (Ptrend = 0.02).

Conclusion: The fathers' active involvement in childcare and housework could reduce the mothers' physical punishment for their children.

背景:以前没有研究报道过父亲参与育儿和家务劳动与母亲体罚之间的关系:以前没有研究报告称父亲参与育儿和家务劳动与母亲体罚之间存在关联:我们利用日本 21 世纪新生儿纵向调查(N = 38554)的数据,分析了父亲在 6 个月时参与育儿和家务劳动的情况以及母亲在 3.5 岁时打孩子屁股的情况。我们对父亲参与育儿和家务的情况进行了评分,并将其分为四等分。打屁股频率按 "经常"、"有时 "或 "完全没有 "进行分类。针对父亲参与育儿和家务的情况,计算了母亲经常打孩子屁股的多变量调整后的几率比(ORs)和 95% 的置信区间(CIs)。我们还根据父亲的工作时间(40-49、50-59 或 ≥ 60 小时/周)对相关性进行了分层:在 16,373 名受访者中,经常打孩子屁股的母亲比例为 4.8%。与最低四分位数相比,父亲参与家务劳动的频率越高,打孩子屁股的风险越低(p 趋势 = 0.001)。对辅助变量的调整削弱了这种相关性,但在父亲参与家务的第三四分位数中观察到了显著的相关性[OR (95% CI):0.77 (0.62-0.96)]。当父亲每周工作少于 50 小时时,父亲的育儿频率与母亲打孩子屁股的可能性之间存在显著的负相关(P 趋势 = 0.02):结论:父亲积极参与育儿和家务劳动可减少母亲体罚孩子的行为。
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引用次数: 0
Impact of the COVID-19 pandemic on changes in tobacco use behaviour: A longitudinal cohort study in Japan. COVID-19 大流行对烟草使用行为变化的影响:日本纵向队列研究。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-23 DOI: 10.2188/jea.JE20240180
Makiko Kanai, Osamu Kanai, Takahiro Tabuchi

Background: Novel tobacco product such as heated tobacco products have recently increased as a result of being promoted less harmful alternatives to cigarettes. The impact of the COVID-19 pandemic on tobacco use may differ depending on the type of tobacco.

Methods: We longitudinally investigated changes in tobacco use over a one-year period using internet-based and self-reported questionnaires among Japanese aged 15 to 79 years. The study was conducted from 2019 to 2021, with participants before the COVID-19 pandemic in February 2020 as prepandemic group and participants after that as pandemic group. Accounting for population bias, we used sampling probability weighting referring to the nationwide data. The association between cessation and the COVID-19 pandemic was evaluated separately for each type of tobacco using logistic regression analysis.

Results: After conducting sampling probability weighting, 1,920 were in the prepandemic group and 2,681 were in the pandemic group. More participants in the pandemic group than in the prepandemic group achieved cessation after one year (13.8% vs. 10.2%, p<0.001). Dual users were more likely to quit during the pandemic than prepandemic (adjusted odds ratio [aOR]=2.56, p<0.001), whereas exclusive novel tobacco users were less likely to quit during the pandemic (aOR=0.66, p=0.041). Tobacco cessation was more frequently achieved among those who had intended to quit at baseline survey among conventional tobacco users (aOR=1.77, p<0.001) and dual users (aOR=2.52, p<0.001); however, this trend was not observed among novel tobacco users (aOR=1.49, p=0.090).

Conclusions: Conventional and novel tobacco use patterns varied in response to the COVID-19 pandemic.

背景:加热烟草制品等新型烟草制品由于被宣传为香烟的低危害替代品而在最近有所增加。COVID-19大流行对烟草使用的影响可能因烟草种类而异:我们使用互联网问卷和自我报告问卷对 15 至 79 岁日本人一年内的烟草使用变化进行了纵向调查。研究于 2019 年至 2021 年进行,2020 年 2 月 COVID-19 大流行前的参与者为流行前组,流行后的参与者为流行后组。考虑到人口偏差,我们参照全国数据采用了抽样概率加权法。使用逻辑回归分析分别评估了每种烟草类型的戒烟与 COVID-19 大流行之间的关联:结果:在进行抽样概率加权后,大流行前组有 1,920 人,大流行组有 2,681 人。大流行组中一年后戒烟的人数多于大流行前组(13.8% vs. 10.2%,pConclusions):传统和新型烟草使用模式因 COVID-19 大流行而异。
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引用次数: 0
Maternal Abnormal Liver Function in Early Pregnancy and Spontaneous Pregnancy Loss: A Retrospective Cohort Study. 孕早期母体肝功能异常与自然妊娠流产:一项回顾性队列研究。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-23 DOI: 10.2188/jea.JE20240233
Huibin Yang, Tianyi Tang, Qianlei Qian, Xiaohua Zhang, Yinan Liu, Xiaoyan Zhou, Yanling Zhang, Xiaotian Chen, Longmei Jin

Background: Spontaneous pregnancy loss (SPL) precedes an increased risk of reduced fertility, while its etiology mechanism remains largely unknown. Liver dysfunction presenting in early pregnancy may represent a pre-existing undiagnosed liver condition affecting fetal development. Here, we investigated whether maternal abnormal liver function in early pregnancy contributed to the incidence of SPL.

Methods: Data on pregnant women were leveraged from the Maternal Health Care Information System in Shanghai City from 2017 to 2021. Liver dysfunction status was defined as having any elevated liver function biomarker levels (LFBs) at the first antenatal visit. SPL cases were defined as fetal death occurring before 28 weeks gestation. Generalized linear models were used to estimate crude and adjusted risk ratios (aRRs) and 95% confidence intervals (CIs).

Results: Among 10175 leveraged pregnant women, 918 (9.0%) SPL cases were recorded. Maternal liver dysfunction in early pregnancy was associated with a 49% increased risk of SPL (RR 1.49, 95% CI 1.22-1.84). This positive association persisted after adjustment for covariates (aRR 1.55, 95% CI 1.26-1.92). Higher γ-glutamyl transferase (GGT) and alkaline phosphatase (ALP) levels were also linked with increased risk of SPL in a linear fashion (aRRs per 1 standard deviation increase: 1.13, 95% CI 1.08-1.17; 1.13, 1.07-1.20, respectively). Similar magnitudes of associations were observed between normal weight and overweight pregnant women in subgroup analysis.

Conclusion: We provide new evidence that maternal abnormal liver function in early pregnancy, as well as GGT and ALP, predisposes to an increased risk of SPL.

背景:自发性妊娠流产(SPL)会增加生育能力下降的风险,但其病因机制在很大程度上仍不清楚。孕早期出现的肝功能异常可能代表着孕前未确诊的影响胎儿发育的肝脏疾病。在此,我们研究了孕早期母体肝功能异常是否会导致 SPL 的发生:孕妇数据来自上海市孕产妇保健信息系统,时间为2017年至2021年。肝功能异常状态定义为首次产前检查时肝功能生物标志物水平(LFBs)升高。SPL病例定义为妊娠28周前发生的胎儿死亡。采用广义线性模型估算粗略风险比(aRR)和调整风险比(aRR)以及95%置信区间(CI):在10175名杠杆孕妇中,记录了918例(9.0%)SPL病例。孕早期母体肝功能异常与 SPL 风险增加 49% 相关(RR 1.49,95% CI 1.22-1.84)。调整协变量后,这种正相关关系仍然存在(aRR 1.55,95% CI 1.26-1.92)。γ-谷氨酰转移酶(GGT)和碱性磷酸酶(ALP)水平较高也与 SPL 风险增加呈线性关系(每增加 1 个标准差的 aRR:1.13,95% CI:1.22-1.84):分别为 1.13,95% CI 1.08-1.17;1.13,1.07-1.20)。在亚组分析中,正常体重和超重孕妇之间的关联程度相似:我们提供的新证据表明,孕早期母体肝功能异常以及 GGT 和 ALP 易导致 SPL 风险增加。
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引用次数: 0
A Short Report on a Single-center Survey of Barium Acute Appendicitis. 诊断钡餐急性阑尾炎的单中心调查简要报告。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-11-05 Epub Date: 2024-09-30 DOI: 10.2188/jea.JE20230334
Taku Harada, Takashi Watari
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引用次数: 0
Changes in mortality during the COVID-19 pandemic in Japan: descriptive analysis of national health statistics up to 2022. 日本 COVID-19 大流行期间死亡率的变化:截至 2022 年的全国卫生统计描述性分析。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-26 DOI: 10.2188/jea.JE20240158
Hirokazu Tanaka, Shuhei Nomura, Kota Katanoda

Background: Amidst the global coronavirus disease (COVID-19) pandemic, Japan has faced a significant public health challenge, evident from the significant increase in mortality rates since 2021. This study described the variations in all-cause and cause-specific changes in mortality up to 2022 in Japan.

Methods: This study used official Vital Statistics from the Ministry of Health, Labour and Welfare (MHLW) to assess the impact of the pandemic on mortality trends. An analysis of all-cause and cause-specific age-standardized mortality rates (ASMRs) from 1995 to 2022 was conducted, employing the 2015 Japan Standard Population. Sex- and cause-specific ASMRs for a particular year were compared with those from the preceding year to assess annual changes.

Results: Among men, the annual all-cause ASMR per 100,000 people increased from 1356.3 in 2021 to 1437.8 in 2022 (6.0% increase). Among women, the annual all-cause ASMR increased from 722.1 in 2021 to 785.8 in 2022 (6.5% increase). Compared with the period 2020 to 2021, COVID-19 (+29.1 per 100,000 people for men and +13.4 per 100,000 people for women), senility (+14.1 per 100,000 people for men and +12.5 per 100,000 people for women), heart disease, malignant neoplasms (for women) and "other causes not classified as major causes" substantially contributed to the increase in all-cause ASMR from 2021 to 2022.

Conclusions: Further long-term monitoring from 2023 onwards is necessary, especially for conditions like senility, cardiovascular disease, and cancer, which may have long-term effects due to changes in healthcare settings, even though the strong countermeasures against COVID-19 were lifted in 2023.

背景:在全球冠状病毒病(COVID-19)大流行的情况下,日本面临着重大的公共卫生挑战,这从2021年以来死亡率的显著上升可以看出。本研究描述了截至 2022 年日本全因死亡率和特定病因死亡率的变化情况:本研究使用厚生劳动省(MHLW)的官方生命统计数据来评估大流行病对死亡率趋势的影响。研究采用 2015 年日本标准人口,对 1995 年至 2022 年的全因和特定原因年龄标准化死亡率(ASMRs)进行了分析。将特定年份的性别和特定病因年龄标准化死亡率与前一年的死亡率进行比较,以评估每年的变化:结果:在男性中,每 10 万人的年度全因 ASMR 从 2021 年的 1356.3 上升到 2022 年的 1437.8(上升 6.0%)。在女性中,每年每 10 万人中全因 ASMR 从 2021 年的 722.1 增加到 2022 年的 785.8(增加 6.5%)。与 2020 年至 2021 年期间相比,COVID-19(男性每 100,000 人中 +29.1,女性每 100,000 人中 +13.4)、衰老(男性每 100,000 人中 +14.1,女性每 100,000 人中 +12.5)、心脏病、恶性肿瘤(女性)和 "未被归类为主要原因的其他原因 "极大地促进了 2021 年至 2022 年期间全因 ASMR 的增长:从 2023 年起,有必要进一步进行长期监测,特别是对于老年病、心血管疾病和癌症等疾病,尽管针对 COVID-19 的强力应对措施已于 2023 年解除,但由于医疗环境的变化,这些疾病可能会产生长期影响。
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引用次数: 0
Estimating the prevalence of and clarifying factors associated with multiple tobacco product use in Japan: a cross-sectional study in 2022. 估算日本多种烟草制品使用率并明确相关因素:2022 年横断面研究。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-26 DOI: 10.2188/jea.JE20240153
Takafumi Yamamoto, Hazem Abbas, Upul Cooray, Tetsuji Yokoyama, Takahiro Tabuchi

BackgroundMultiple tobacco product (MTP) use is a public health concern due to their combined adverse health effects. MTP use may have increased since heated tobacco products (HTPs) became more prevalent in Japan. This study aimed to (1) estimate the recent prevalence of MTP use and clarify the associated factors compared to (2) non-smokers and (3) single-product users.MethodWe used data from an internet survey conducted in February 2022. The prevalence of MTP use in Japan was estimated using inverse probability-weighted scores from this survey and a nationwide survey by the Japanese government. Tobacco products include six types: cigarettes, HTPs, e-cigarettes, cigars, pipe/water pipes, and smokeless tobacco products. MTP use was defined using the outcome variable (no use, single-product use, and MTP use) based on these six types of use. Using multivariate logistic regression, we calculated the adjusted odds ratios and 95% confidence intervals (CI) to clarify factors associated with MTP use compared to non-smokers, adjusting demographic variables, psychological distress, self-rated health, and alcohol use. Using multivariate Poisson regression, we calculated the adjusted prevalence ratios (aPR) and 95%CI to clarify factors associated with MTP use among smokers, adjusting for these covariates and smoking-related factors like workplace and home smoking rules.ResultsWe analyzed 30,141 participants whose mean age was 47.8 years (standard deviation = 17.9), and 14,722 participants were male (48.8%). The estimated prevalence of MTP use was 6.8%. The most common combination of MTP use was cigarettes and HTPs. Compared to non-smokers, being younger, male, low education, poor psychological distress, poor self-rated health, and alcohol use were factors associated with MTP use. Among smokers, workplace smoking rules, such as a partial smoking ban and no smoking ban, were not associated with MTP use compared to the indoor smoking ban. However, participants with no home smoking ban were positively associated with MTP use compared to those with a ban on both cigarettes and HTPs at home (both cigarettes and HTPs allowed aPR=1.36, 95%CI 1.15 to 1.61, HTPs only allowed aPR=1.73, 95%CI 1.43 to 2.10).ConclusionMTP users may account for a high percentage of Japanese smokers.

背景多种烟草制品(MTP)的使用因其对健康的综合不良影响而备受公众关注。自从加热烟草制品(HTPs)在日本变得越来越普遍后,MTP的使用可能有所增加。本研究旨在(1)估算近期MTP的使用流行率,并阐明与(2)非吸烟者和(3)单一产品使用者相比的相关因素。我们使用了2022年2月进行的一项互联网调查的数据,并利用该调查和日本政府进行的一项全国性调查的反概率加权分数估算了日本MTP的使用流行率。烟草制品包括六种类型:香烟、HTP、电子烟、雪茄、烟斗/水烟和无烟烟草制品。根据这六种烟草制品的使用情况,使用结果变量(不使用、使用单一烟草制品和使用 MTP)来定义 MTP 的使用情况。通过多变量逻辑回归,我们计算了调整后的几率比和95%置信区间(CI),以明确与非吸烟者相比,使用MTP的相关因素,并对人口统计学变量、心理困扰、自我健康评价和饮酒情况进行了调整。利用多变量泊松回归,我们计算了调整后的流行率(aPR)和95%置信区间(CI),以明确与吸烟者使用MTP相关的因素,同时调整了这些协变量以及与吸烟相关的因素,如工作场所和家庭的吸烟规定。估计使用 MTP 的流行率为 6.8%。最常见的 MTP 组合是香烟和 HTP。与非吸烟者相比,年轻、男性、教育程度低、心理压力大、自评健康状况差以及饮酒是与使用MTP相关的因素。在吸烟者中,与室内禁烟相比,工作场所的吸烟规定(如部分禁烟和禁止吸烟)与MTP的使用无关。然而,与禁止在家中吸食香烟和HTPs的参与者相比,禁止在家中吸食香烟和HTPs的参与者与MTP的使用呈正相关(允许吸食香烟和HTPs的PR=1.36,95%CI为1.15至1.61;只允许吸食HTPs的PR=1.73,95%CI为1.43至2.10)。
{"title":"Estimating the prevalence of and clarifying factors associated with multiple tobacco product use in Japan: a cross-sectional study in 2022.","authors":"Takafumi Yamamoto, Hazem Abbas, Upul Cooray, Tetsuji Yokoyama, Takahiro Tabuchi","doi":"10.2188/jea.JE20240153","DOIUrl":"https://doi.org/10.2188/jea.JE20240153","url":null,"abstract":"<p><p>BackgroundMultiple tobacco product (MTP) use is a public health concern due to their combined adverse health effects. MTP use may have increased since heated tobacco products (HTPs) became more prevalent in Japan. This study aimed to (1) estimate the recent prevalence of MTP use and clarify the associated factors compared to (2) non-smokers and (3) single-product users.MethodWe used data from an internet survey conducted in February 2022. The prevalence of MTP use in Japan was estimated using inverse probability-weighted scores from this survey and a nationwide survey by the Japanese government. Tobacco products include six types: cigarettes, HTPs, e-cigarettes, cigars, pipe/water pipes, and smokeless tobacco products. MTP use was defined using the outcome variable (no use, single-product use, and MTP use) based on these six types of use. Using multivariate logistic regression, we calculated the adjusted odds ratios and 95% confidence intervals (CI) to clarify factors associated with MTP use compared to non-smokers, adjusting demographic variables, psychological distress, self-rated health, and alcohol use. Using multivariate Poisson regression, we calculated the adjusted prevalence ratios (aPR) and 95%CI to clarify factors associated with MTP use among smokers, adjusting for these covariates and smoking-related factors like workplace and home smoking rules.ResultsWe analyzed 30,141 participants whose mean age was 47.8 years (standard deviation = 17.9), and 14,722 participants were male (48.8%). The estimated prevalence of MTP use was 6.8%. The most common combination of MTP use was cigarettes and HTPs. Compared to non-smokers, being younger, male, low education, poor psychological distress, poor self-rated health, and alcohol use were factors associated with MTP use. Among smokers, workplace smoking rules, such as a partial smoking ban and no smoking ban, were not associated with MTP use compared to the indoor smoking ban. However, participants with no home smoking ban were positively associated with MTP use compared to those with a ban on both cigarettes and HTPs at home (both cigarettes and HTPs allowed aPR=1.36, 95%CI 1.15 to 1.61, HTPs only allowed aPR=1.73, 95%CI 1.43 to 2.10).ConclusionMTP users may account for a high percentage of Japanese smokers.</p>","PeriodicalId":15799,"journal":{"name":"Journal of Epidemiology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
News coverage of older drivers' fatal car crashes: is it over-represented? 关于老年司机致命车祸的新闻报道:是否报道过多?
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-26 DOI: 10.2188/jea.JE20240299
Masao Ichikawa, Rie Tanaka, Akito Nakanishi, Yukie Sano

Background: Japan's stringent licensing policies for older drivers have not been questioned, possibly due to negative perceptions of older drivers potentially influenced by media coverage of their car crashes. We examined whether older drivers' fatal crashes are over-represented in the news articles.

Methods: To examine the news coverage of fatal crashes that occurred between January 2016 and December 2020, we extracted driver- and crash-related data from articles reporting fatal crashes in the two best-selling newspapers, Yomiuri and Asahi. We obtained the corresponding data of police-reported fatal crashes during the same period. We calculated the proportion of newspaper-reported fatal crashes to police-reported fatal crashes by at-fault driver's age group and crash characteristics.

Results: Of 12,987 police-reported fatal crashes, 5,888 (45%) and 2,909 (22%) crashes were reported in Yomiuri and Asahi newspapers, respectively. Excluding 2,098 crashes where at-fault drivers or their ages were not identifiable, Yomiuri reported 39%, 35%, and 31%, and Asahi reported 20%, 16%, and 14% of fatal crashes caused by drivers aged <30 years, 30-69 years, and 70 years or older, respectively. Crashes that caused more fatalities or killed children tended to be reported regardless of at-fault drivers' age groups. Compared with young and middle-aged drivers, older drivers' fatal crashes involving child fatalities were more reported, whereas their single fatal crashes ending in their own deaths were less reported.

Conclusion: Older drivers' at-fault fatal crashes were not over-represented in the news coverage of overall fatal crashes, and their crashes killing themselves were under-reported.

背景:日本对老年司机实行严格的驾照政策,但这一政策并未受到质疑,这可能是由于媒体对老年司机车祸的报道可能会影响人们对老年司机的负面看法。我们研究了老年司机的致命车祸是否在新闻报道中出现过多:为了研究 2016 年 1 月至 2020 年 12 月期间发生的致命车祸的新闻报道,我们从《读卖新闻》和《朝日新闻》两家最畅销报纸上报道致命车祸的文章中提取了与司机和车祸相关的数据。我们还获得了同期警方报告的致命车祸的相应数据。我们按肇事司机的年龄组和车祸特征计算了报纸报道的致命车祸与警方报道的致命车祸的比例:在警方报告的 12,987 起致命车祸中,《读卖新闻》和《朝日新闻》分别报道了 5,888 起(45%)和 2,909 起(22%)。除去 2,098 起无法确定肇事司机或其年龄的交通事故,《读卖新闻》和《朝日新闻》分别报道了 39%、35% 和 31%、20%、16% 和 14%的死亡交通事故是由年龄在 20 岁以下的司机造成的:在新闻报道中,老年驾驶员的过失致人死亡交通事故在整个致人死亡交通事故中的比例并不高,而对他们的交通事故致人死亡却报道不足。
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引用次数: 0
Comparison of Demographic and Clinical Characteristics of Taiwan Biobank Participants with Nonparticipants. 台湾生物库参与者与非参与者的人口统计学和临床特征比较。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-26 DOI: 10.2188/jea.JE20240297
Chi-Shin Wu, Le-Yin Hsu, Chen-Yang Shen, Wei J Chen, Mei-Chen Lin, Chun Chieh Fan, Shi-Heng Wang

Background: This study investigated fundamental demographic variables within the Taiwan Biobank (TWBB) and compared them with national demographic statistics. Additionally, a matched cohort analysis compared TWBB participants with nonparticipants to uncover disparities in sociodemographic and clinical characteristics.

Methods: A total of 128,663 individuals aged 30 to 70 without cancer were recruited within the TWBB, and 514,652 nonparticipants matched by age and sex were randomly selected from the National Health Insurance claims database. Sociodemographic variables, healthcare utilization metrics, underlying medical conditions, and subsequent mortality and cancer risk were analyzed.

Results: TWBB participants were more likely to be female, older, married, higher educated, with higher incomes, and urban residency. Healthcare utilization metrics showed minimal differences. Pre-cohort entry, TWBB participants had a higher prevalence of certain medical conditions, such as peptic ulcer disease, osteoarthritis, osteoporosis, and uterine leiomyoma in females. During follow-up periods, elevated mortality rates were observed among TWBB participants but decreased cancer risk.

Conclusion: The TWBB cohort exhibits disparities in sociodemographic and health-related attributes compared to the general population, comprising older, females, married, higher educated, higher income, and predominantly in urban areas. While mortality rates are slightly elevated within the TWBB cohort, cancer incidence rates are lower. Despite limitations in representativeness, the TWBB's size and exposure measures offer valuable insights into associations between exposures and health conditions.

研究背景本研究调查了台湾生物样本库(TWBB)中的基本人口统计学变量,并将其与全国人口统计学数据进行了比较。此外,一项匹配队列分析比较了台湾生物库参与者和非参与者,以揭示社会人口和临床特征的差异:在 TWBB 中招募了 128,663 名年龄在 30 岁至 70 岁之间的非癌症患者,并从国民健康保险索赔数据库中随机抽取了 514,652 名年龄和性别匹配的非参与者。对社会人口学变量、医疗保健使用指标、基础医疗条件以及随后的死亡率和癌症风险进行了分析:结果:TWBB 参与者更可能是女性、老年人、已婚者、受过高等教育者、收入较高者和城市居民。医疗保健利用率指标显示差异很小。在加入队列前,TWBB 参与者的某些疾病患病率较高,如消化性溃疡、骨关节炎、骨质疏松症和女性子宫肌瘤。在随访期间,观察到 TWBB 参与者的死亡率升高,但癌症风险降低:与普通人群相比,TWBB 群体在社会人口学和健康相关属性方面存在差异,包括老年人、女性、已婚、受过高等教育、收入较高、主要居住在城市地区。虽然 TWBB 群体的死亡率略高,但癌症发病率较低。尽管 TWBB 在代表性方面存在局限性,但其规模和暴露测量方法为了解暴露与健康状况之间的关联提供了宝贵的信息。
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引用次数: 0
Prevalence, incidence, and recovery of metabolic dysfunction-associated steatotic liver disease and associations with weight loss and lipid reduction in a Chinese community-based cohort. 中国社区队列中代谢功能障碍相关性脂肪性肝病的患病率、发病率和恢复情况,以及与减肥和降脂的关系。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-12 DOI: 10.2188/jea.JE20240224
Yurou Xu, Youyi Wang, Xiajing Yao, Qi Zhao, Bo Chen, Na Wang, Tiejun Zhang, Yonggen Jiang, Yiling Wu, Na He, Genming Zhao, Zhongxing Sun, Xing Liu

Background: As the most common chronic liver disease worldwide, the natural history of metabolic dysfunction-associated steatotic liver disease (MASLD) in general population is barely reported.

Methods: The Shanghai Suburban Adult Cohort and Biobank study recruited 36,404 adults between 2016 and 2017, and followed up 25,085 participants between 2019 and 2023 in Songjiang District. A questionnaire survey was conducted by face-to-face interview, and physical examination and laboratory tests were conducted. MASLD was diagnosed by liver ultrasound and the cardiometabolic risk factors (CMRF).

Results: A total of 36,122 and 21,831 participants met the criteria for baseline and follow-up analyses. The prevalence of MASLD at baseline was 36.8% overall, and 73.6% among those with a BMI over 28 kg/m2. After a median follow-up time of 4.26 years, the incidence density for MASLD was 8.4, and the recovery density was 11.4 per 100 person-years overall, and was 20.0 and 8.4 per 100 person-years for those with baseline BMI over 28 kg/m2. Per 1 kg/m2 increase in baseline BMI was associated with an 15% increase in incidence (HR=1.15, 95%CI: 1.14-1.17) and an 8% decrease in recovery (HR=0.92, 95%CI: 0.90-0.93). From baseline to follow-up visit, participants who remained non-obese, or remained normal cardiometabolic status always showed the lowest incidence and the highest recovery rate, followed by those with improved status.

Conclusions: The prevalence and incidence of MASLD were high among Shanghai residents, and active recovery was also observed. Obesity was the most important risk factor, and weight loss and lipid level reduction were beneficial for preventing or reversing MASLD.

背景:作为全球最常见的慢性肝病,代谢功能障碍相关性脂肪性肝病(MASLD)在普通人群中的自然史几乎没有报道:作为全球最常见的慢性肝病,代谢功能障碍相关性脂肪性肝病(MASLD)在普通人群中的自然史几乎没有报道:上海郊区成人队列和生物库研究于2016年至2017年在松江区招募了36404名成人,并于2019年至2023年对25085名参与者进行了随访。研究人员通过面对面访谈进行了问卷调查,并进行了体格检查和实验室检测。通过肝脏超声和心脏代谢风险因素(CMRF)诊断MASLD:分别有 36122 人和 21831 人符合基线分析和随访分析的标准。基线时MASLD的患病率为36.8%,体重指数超过28 kg/m2的人群中MASLD的患病率为73.6%。中位随访时间为 4.26 年后,MASLD 的发病密度为每 100 人年 8.4 例,恢复密度为每 100 人年 11.4 例,基线体重指数超过 28 kg/m2 的人群的发病密度为每 100 人年 20.0 例,恢复密度为每 100 人年 8.4 例。基线体重指数每增加 1 千克/平方米,发病率就会增加 15%(HR=1.15,95%CI:1.14-1.17),康复率就会降低 8%(HR=0.92,95%CI:0.90-0.93)。从基线到随访,保持不肥胖或心脏代谢状况正常的参与者的发病率最低,康复率最高,其次是状况有所改善的参与者:结论:MASLD在上海居民中的流行率和发病率都很高,并且也观察到了积极的恢复情况。肥胖是最重要的危险因素,减轻体重和降低血脂水平有利于预防或逆转 MASLD。
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引用次数: 0
Careful Consideration of Study Limitations When Interpreting the Association Between Induced Abortion and Breast Cancer Risk. 在解释人工流产与乳腺癌风险之间的关联时,应仔细考虑研究的局限性。
IF 3.7 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-05 Epub Date: 2024-03-09 DOI: 10.2188/jea.JE20230362
Tiana Fontanilla
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引用次数: 0
期刊
Journal of Epidemiology
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