Pub Date : 2020-12-30DOI: 10.31491/csrc.2020.12.065
M. O. Beyaz, Nur Gizem Elipek, I. Demir, D. Oztas, M. Ulukan, T. Sarıtas, M. Uğurlucan, H. Turkoglu
Aortic stenosis is a rarely seen condition in the pediatric population. Valve replacement is a treatment option for patients who do not benefit from medical or interventional procedures. In this report, we described our surgical treatment strategy in a 17-year-old patient who developed patient-prosthesis mismatch long after initial aortic valve replacement during the childhood period. Keywords: Konno-rastan procedure; manouguian technique; aortic root enlargement
{"title":"Konno-rastan procedure combined with manougian root enlargement for small aortic root","authors":"M. O. Beyaz, Nur Gizem Elipek, I. Demir, D. Oztas, M. Ulukan, T. Sarıtas, M. Uğurlucan, H. Turkoglu","doi":"10.31491/csrc.2020.12.065","DOIUrl":"https://doi.org/10.31491/csrc.2020.12.065","url":null,"abstract":"Aortic stenosis is a rarely seen condition in the pediatric population. Valve replacement is a treatment option for patients who do not benefit from medical or interventional procedures. In this report, we described our surgical treatment strategy in a 17-year-old patient who developed patient-prosthesis mismatch long after initial aortic valve replacement during the childhood period. Keywords: Konno-rastan procedure; manouguian technique; aortic root enlargement","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125308826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-30DOI: 10.31491/csrc.2020.12.063
F. Borulu, B. Erkut
Background: Patients with kidney failure need dialysis until transplant or die. Hemodialysis is one of the preferred methods for these patients. Many studies have been conducted on the factors affecting the patency of arteriovenous fistulas, which are frequently used for hemodialysis. In this study, we investigated the importance of age. Methods: 442 patients (256 men, 186 women) who underwent arteriovenous fistula operation between May 2013 and Oct 2020 were retrospectively analyzed. Surgical operations were performed by 5 different cardiovascular surgeons for hemodialysis in two different institutions in our region. The patients were divided into two groups, Group I (number of patients under 40 years old; n = 201) and Group II (number of patients over 40 years old; n = 241). The primary patency was the time interval between the formation of arteriovenous fistula and any intervention for initial thrombosis and recanalization. Secondary patency was not evaluated in this study. The effects of age on primary exposure rates were investigated for both groups. Results: Primary arteriovenous fistula patency rates were lower in patients over 40 years of age. For this reason, more care should be taken in surgery to create fistulas in patients over the age of 40, and the follow-up of patients should be done more tightly. Conclusion: Complicated external hernias occur in all age groups but are more common in older age and show preponderance in males. All patients present with irreducible swelling with no cough impulse. The indirect inguinal hernia is the most common type and herniorrhaphy is the most preferred operative procedure in the complicated hernia. Wound sepsis was the most common complication. Morbidity and mortality may be attenuated with proper surgical and post-operative management. Keywords: Arteriovenous fistula; hemodialysis; age; surgery; patency
{"title":"The importance of age in terms of fistula patency in chronic hemodialysis patients: 7-year follow-up","authors":"F. Borulu, B. Erkut","doi":"10.31491/csrc.2020.12.063","DOIUrl":"https://doi.org/10.31491/csrc.2020.12.063","url":null,"abstract":"Background: Patients with kidney failure need dialysis until transplant or die. Hemodialysis is one of the preferred methods for these patients. Many studies have been conducted on the factors affecting the patency of arteriovenous fistulas, which are frequently used for hemodialysis. In this study, we investigated the importance of age. Methods: 442 patients (256 men, 186 women) who underwent arteriovenous fistula operation between May 2013 and Oct 2020 were retrospectively analyzed. Surgical operations were performed by 5 different cardiovascular surgeons for hemodialysis in two different institutions in our region. The patients were divided into two groups, Group I (number of patients under 40 years old; n = 201) and Group II (number of patients over 40 years old; n = 241). The primary patency was the time interval between the formation of arteriovenous fistula and any intervention for initial thrombosis and recanalization. Secondary patency was not evaluated in this study. The effects of age on primary exposure rates were investigated for both groups. Results: Primary arteriovenous fistula patency rates were lower in patients over 40 years of age. For this reason, more care should be taken in surgery to create fistulas in patients over the age of 40, and the follow-up of patients should be done more tightly. Conclusion: Complicated external hernias occur in all age groups but are more common in older age and show preponderance in males. All patients present with irreducible swelling with no cough impulse. The indirect inguinal hernia is the most common type and herniorrhaphy is the most preferred operative procedure in the complicated hernia. Wound sepsis was the most common complication. Morbidity and mortality may be attenuated with proper surgical and post-operative management. Keywords: Arteriovenous fistula; hemodialysis; age; surgery; patency","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130790878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-30DOI: 10.31491/csrc.2020.12.064
D. Verma, Sarthak Sharma, L. Garg, Aishwarya Tinaikar
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2) involving the respiratory tract started in 2019 in Wuhan, China but spread to almost all parts of the world to the extent that it was declared a pandemic by WHO. As more and more cases are detected, the involvement of systems other than respiratory was observed and nearly 5 to 50 % of patients have abdominal symptoms like pain and diarrhea. During the course of treatment, few patients developed a rare complication of gastrointestinal perforation. Three cases (two with colonic perforation and one with gastric perforation) of gastrointestinal perforation in COVID-19 positive patient are reported in the article with a review of the literature regarding the various hypothesis of intestinal perforation in these patients. Keywords: COVID-19; gastrointestinal perforation; severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2); Tocilizumab
{"title":"Gastrointestinal perforation in COVID-19 patients – case series and review of the literature","authors":"D. Verma, Sarthak Sharma, L. Garg, Aishwarya Tinaikar","doi":"10.31491/csrc.2020.12.064","DOIUrl":"https://doi.org/10.31491/csrc.2020.12.064","url":null,"abstract":"Severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2) involving the respiratory tract started in 2019 in Wuhan, China but spread to almost all parts of the world to the extent that it was declared a pandemic by WHO. As more and more cases are detected, the involvement of systems other than respiratory was observed and nearly 5 to 50 % of patients have abdominal symptoms like pain and diarrhea. During the course of treatment, few patients developed a rare complication of gastrointestinal perforation. Three cases (two with colonic perforation and one with gastric perforation) of gastrointestinal perforation in COVID-19 positive patient are reported in the article with a review of the literature regarding the various hypothesis of intestinal perforation in these patients. Keywords: COVID-19; gastrointestinal perforation; severe acute respiratory syndrome coronavirus-2 (SARS-CoV 2); Tocilizumab","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123874245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-25DOI: 10.31491/CSRC.2020.09.061
Sajad Ahmad Salati
Sajad Ahmad Salati 25 was conducted to study the status and patency of the shunt. A multiaxial CT scan of the abdomen and pelvis with oral and intravenous contrast (Figure 1: A–F) showed a heterogeneous liver and a patent TIPS stent communicating the porto-venous and systemic system. The portal vein was distended with multiple collaterFigure 1. CT Scan showing patent TIPS (red arrows) and dilated collaterals (blue arrow). (A) Scout film. (B) Coronal view. (C) Sagittal view. (D) Transverse section (without contrast). (E,F) Transverse section (with contrast). Clin Surg Res Commun 2020; 4(3): 25-26
Sajad Ahmad Salati 25是为了研究分流的状态和通畅。腹部和骨盆的多轴CT扫描与口服和静脉造影剂(图1:A - f)显示异质肝脏和专利TIPS支架连接门静脉和全身系统。门静脉多支扩张图1。CT扫描显示TIPS(红色箭头)和侧枝扩张(蓝色箭头)。(A)童军电影。(B)冠状面。(C)矢状面。(D)横切面(无对比)。(E,F)横切面(有对比)。临床外科康复协会2020;4 (3): 25 - 26
{"title":"Transjugular intrahepatic portosystemic shunt in Budd-Chiari syndrome","authors":"Sajad Ahmad Salati","doi":"10.31491/CSRC.2020.09.061","DOIUrl":"https://doi.org/10.31491/CSRC.2020.09.061","url":null,"abstract":"Sajad Ahmad Salati 25 was conducted to study the status and patency of the shunt. A multiaxial CT scan of the abdomen and pelvis with oral and intravenous contrast (Figure 1: A–F) showed a heterogeneous liver and a patent TIPS stent communicating the porto-venous and systemic system. The portal vein was distended with multiple collaterFigure 1. CT Scan showing patent TIPS (red arrows) and dilated collaterals (blue arrow). (A) Scout film. (B) Coronal view. (C) Sagittal view. (D) Transverse section (without contrast). (E,F) Transverse section (with contrast). Clin Surg Res Commun 2020; 4(3): 25-26","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123145408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-25DOI: 10.31491/CSRC.2020.09.060
Veranis Sotiris, Karydakis Ploutarchos, T. Margaritis, Spanou Kallirroi, K. George
Atypical choroid plexus papillomas are rare in adults, especially in an extraventricular location. We present a case of a 42-year-old male patient suffering from a foramen magnum choroid plexus papilloma, which resembled meningioma in an initial evaluation, who developed dizziness, hearing loss, and gait disturbance. The patient was treated with suboccipital craniotomy and the tumor was partially removal. We describe the technique and postoperative complications. We also review other published cases of atypical choroid plexus papillomas of the posterior fossa in adults. Keywords: Papilloma; foramen magnum; suboccipital craniotomy; posterior fossa
{"title":"Foramen magnum papilloma case report and review of the literature","authors":"Veranis Sotiris, Karydakis Ploutarchos, T. Margaritis, Spanou Kallirroi, K. George","doi":"10.31491/CSRC.2020.09.060","DOIUrl":"https://doi.org/10.31491/CSRC.2020.09.060","url":null,"abstract":"Atypical choroid plexus papillomas are rare in adults, especially in an extraventricular location. We present a case of a 42-year-old male patient suffering from a foramen magnum choroid plexus papilloma, which resembled meningioma in an initial evaluation, who developed dizziness, hearing loss, and gait disturbance. The patient was treated with suboccipital craniotomy and the tumor was partially removal. We describe the technique and postoperative complications. We also review other published cases of atypical choroid plexus papillomas of the posterior fossa in adults. Keywords: Papilloma; foramen magnum; suboccipital craniotomy; posterior fossa","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127678121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-29DOI: 10.31491/csrc.2020.06.050
Sameh Abdelhay, M. Moussa, M. Elsherbeny
Background: The diagnosis of esophageal stricture after caustic ingestion is based on clinical symptoms of dysphagia, regurgitation and chocking that is evident initially in the acute stage. These symptoms may ameliorate by time or proceed to evident stricture due to fibrosis. This will need either dye esophagogram or Esophagoscopy which is better to be done not before the lapse of at least 6 weeks from injury. Esophageal dilatation using wire-guided dilators is the cornerstone of treatment. The frequency of dilatation is based on recurrence of dysphagia and in multiple strictures, repeated sessions with multi-level injection of steroids and graded dilatation is needed. Failure of dilatation or occurrence of complications may necessitate esophageal replacement and usually we prefer the transverse colon based on the left colic vessels in retrosternal position to treat the condition. We aimed to review the management of caustic esophageal strictures based on what is known and adding our experience in this aspect. Methods: We reviewed the articles discussing management of caustic esophageal strictures in the last twenty years. We added our experience of more than forty years managing an average of thirty new cases every year. Results: Management of caustic esophageal strictures has changed in the last years. Advanced endoscopic techniques of dilatation reduced the need for esophageal replacement. Conclusions: Caustic esophageal strictures could be managed successfully with advanced techniques of endoscopic dilatation. Keywords: Caustic stricture; esophageal dilatation; esophagoscopy; esophageal replacement
{"title":"Caustic esophageal stricture from diagnosis untill cure","authors":"Sameh Abdelhay, M. Moussa, M. Elsherbeny","doi":"10.31491/csrc.2020.06.050","DOIUrl":"https://doi.org/10.31491/csrc.2020.06.050","url":null,"abstract":"Background: The diagnosis of esophageal stricture after caustic ingestion is based on clinical symptoms of dysphagia, regurgitation and chocking that is evident initially in the acute stage. These symptoms may ameliorate by time or proceed to evident stricture due to fibrosis. This will need either dye esophagogram or Esophagoscopy which is better to be done not before the lapse of at least 6 weeks from injury. Esophageal dilatation using wire-guided dilators is the cornerstone of treatment. The frequency of dilatation is based on recurrence of dysphagia and in multiple strictures, repeated sessions with multi-level injection of steroids and graded dilatation is needed. Failure of dilatation or occurrence of complications may necessitate esophageal replacement and usually we prefer the transverse colon based on the left colic vessels in retrosternal position to treat the condition. We aimed to review the management of caustic esophageal strictures based on what is known and adding our experience in this aspect. Methods: We reviewed the articles discussing management of caustic esophageal strictures in the last twenty years. We added our experience of more than forty years managing an average of thirty new cases every year. Results: Management of caustic esophageal strictures has changed in the last years. Advanced endoscopic techniques of dilatation reduced the need for esophageal replacement. Conclusions: Caustic esophageal strictures could be managed successfully with advanced techniques of endoscopic dilatation. Keywords: Caustic stricture; esophageal dilatation; esophagoscopy; esophageal replacement","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115467402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-20DOI: 10.31491/csrc.2020.03.048
Z. Qiu, Yang Yu, ZhanYing Ma, P. Yan, Yixuan Gao, Qixiang Wang
Objectives: In this study, we aimed to supplement the database of intervertebral foramen by measuring the parameters of the lower lumbar spine related to the articular process of the X-ray, which could lay a theoretical foundation for the individualized surgery of transforaminal endoscopic spine technique (TEST). Methods: Anteroposterior and lateral X-rays of the lumbar spine from 104 adults (50 male and 54 female) who met the measurement criteria were selected. The height and width of the intervertebral foramen, the height of the intervertebral space, the length from the superior articular process (SAP) to the lower edge of the upper lumbar pedicle, and the length from SAP to posterior margin of superior vertebra posterior edge were measured. Results: There was no significant difference in the shape of the lower lumbar intervertebral foramen between normal adult men and women. There were significant differences in parameters related to the lower lumbar intervertebral foramen between the age group from 40 to 60 and above 60, and especially those related to the SAP. Conclusion: Parameters of the lower lumbar intervertebral foramen were obtained from 104 normal adults, which supplemented the lumbar intervertebral foramen database. After the age of 60, the morphology of the lower lumbar intervertebral foramen was significantly changed in normal adults, and especially parameters related to the SAP. This study provided a reference for individualized minimally invasive surgery using TEST for elderly people over 60 years of age. Keywords : Transforaminal endoscopic spine technique; Superior articular process; Intervertebral foramen; Lower lumbar spine; X-ray; Age
{"title":"X-ray measurement and analysis on parameters of intervertebral foramen in the lower lumbar spine associated with the superior articular process","authors":"Z. Qiu, Yang Yu, ZhanYing Ma, P. Yan, Yixuan Gao, Qixiang Wang","doi":"10.31491/csrc.2020.03.048","DOIUrl":"https://doi.org/10.31491/csrc.2020.03.048","url":null,"abstract":"Objectives: In this study, we aimed to supplement the database of intervertebral foramen by measuring the parameters of the lower lumbar spine related to the articular process of the X-ray, which could lay a theoretical foundation for the individualized surgery of transforaminal endoscopic spine technique (TEST). Methods: Anteroposterior and lateral X-rays of the lumbar spine from 104 adults (50 male and 54 female) who met the measurement criteria were selected. The height and width of the intervertebral foramen, the height of the intervertebral space, the length from the superior articular process (SAP) to the lower edge of the upper lumbar pedicle, and the length from SAP to posterior margin of superior vertebra posterior edge were measured. Results: There was no significant difference in the shape of the lower lumbar intervertebral foramen between normal adult men and women. There were significant differences in parameters related to the lower lumbar intervertebral foramen between the age group from 40 to 60 and above 60, and especially those related to the SAP. Conclusion: Parameters of the lower lumbar intervertebral foramen were obtained from 104 normal adults, which supplemented the lumbar intervertebral foramen database. After the age of 60, the morphology of the lower lumbar intervertebral foramen was significantly changed in normal adults, and especially parameters related to the SAP. This study provided a reference for individualized minimally invasive surgery using TEST for elderly people over 60 years of age. Keywords : Transforaminal endoscopic spine technique; Superior articular process; Intervertebral foramen; Lower lumbar spine; X-ray; Age","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127872005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-25DOI: 10.31491/csrc.2020.03.045
K. Chukwubuike
Background: Intestinal resection in children is an important surgical procedure because of the possible complications that may arise from it. Late presentation and ignorance in developing countries have made intestinal resection a frequent surgical procedure. Methods: This was a retrospective study of children that had intestinal resection in the pediatric surgery unit of Enugu State University Teaching Hospital, Enugu, Nigeria. The medical records of the pediatric patients that underwent intestinal resection over a 10-year period were evaluated for the indications that prompted the surgery. The other parameters that were assessed included the patients’ demographics, the duration of symptoms before presentation, the time interval between presentation and intervention, the complications arising from the intestinal resection, and the outcome. Results: There were 52 cases of intestinal resection with an age range of 1–168 months (median 10 months) and a male to female ratio of 2.25:1. There were 9 neonates (less than one month of age), 29 infants (greater than one month but less than one year of age) and 14 children (older than 1 year of age). The following were the indications for intestinal resection: gangrenous/irreducible intussusception (28 or 53.8%), strangulated external hernia (7 or 13.5%), typhoid intestinal perforation (6 or 11.5%), intestinal atresia (3 or 5.8%), gastroschisis (3 or 5.8%), midgut volvulus (3 or 5.8%), and abdominal trauma (2 or 3.8%). The following definitive surgical procedures were performed: right hemicolectomy with ileotransverse anastomosis (28 or 53.8%), segmental resection with end-to-end anastomosis (20 or 38.5%), and massive intestinal resection with end-to-end anastomosis (4 or 7.7%). The median duration of symptoms prior to presentation and the median duration from presentation to surgery were 3 days and 2 days, respectively. The mean duration of hospital stay was 15 days. Twenty patients (38.4%) developed complications, which included surgical site infection (8 or 15.4%), enterocutanous fistula (6 or 11.5%), intra-peritoneal abscess (4 or 7.7%), and adhesive intestinal obstruction (2 or 3.8%). There were 8 deaths, which accounted for 15.4% of the patients. Conclusion: Intestinal resection was performed most often for intussusception. Late presentation and ignorance contributed significantly to the number of intestinal resections required. Keywords: Children; intestinal resection; experience; intussusception; hernia
{"title":"Intestinal Resection in Children: Our Experience in Enugu, Nigeria","authors":"K. Chukwubuike","doi":"10.31491/csrc.2020.03.045","DOIUrl":"https://doi.org/10.31491/csrc.2020.03.045","url":null,"abstract":"Background: Intestinal resection in children is an important surgical procedure because of the possible complications that may arise from it. Late presentation and ignorance in developing countries have made intestinal resection a frequent surgical procedure. Methods: This was a retrospective study of children that had intestinal resection in the pediatric surgery unit of Enugu State University Teaching Hospital, Enugu, Nigeria. The medical records of the pediatric patients that underwent intestinal resection over a 10-year period were evaluated for the indications that prompted the surgery. The other parameters that were assessed included the patients’ demographics, the duration of symptoms before presentation, the time interval between presentation and intervention, the complications arising from the intestinal resection, and the outcome. Results: There were 52 cases of intestinal resection with an age range of 1–168 months (median 10 months) and a male to female ratio of 2.25:1. There were 9 neonates (less than one month of age), 29 infants (greater than one month but less than one year of age) and 14 children (older than 1 year of age). The following were the indications for intestinal resection: gangrenous/irreducible intussusception (28 or 53.8%), strangulated external hernia (7 or 13.5%), typhoid intestinal perforation (6 or 11.5%), intestinal atresia (3 or 5.8%), gastroschisis (3 or 5.8%), midgut volvulus (3 or 5.8%), and abdominal trauma (2 or 3.8%). The following definitive surgical procedures were performed: right hemicolectomy with ileotransverse anastomosis (28 or 53.8%), segmental resection with end-to-end anastomosis (20 or 38.5%), and massive intestinal resection with end-to-end anastomosis (4 or 7.7%). The median duration of symptoms prior to presentation and the median duration from presentation to surgery were 3 days and 2 days, respectively. The mean duration of hospital stay was 15 days. Twenty patients (38.4%) developed complications, which included surgical site infection (8 or 15.4%), enterocutanous fistula (6 or 11.5%), intra-peritoneal abscess (4 or 7.7%), and adhesive intestinal obstruction (2 or 3.8%). There were 8 deaths, which accounted for 15.4% of the patients. Conclusion: Intestinal resection was performed most often for intussusception. Late presentation and ignorance contributed significantly to the number of intestinal resections required. Keywords: Children; intestinal resection; experience; intussusception; hernia","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"542 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125938298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-29DOI: 10.31491/csrc.2019.09.004
H. Sleem, I. Sharabasy, R. Foad
Salivary gland tumors account for fewer than 3% of the head and neck tumors. Typically salivary gland neoplasm presented as a single swelling localized to one salivary gland. A more unusual event is the development of multiple neoplasms located either in different glands or in one gland. This manuscript present a case of palatal swelling diagnosed by incisional biopsy as polymorphous adenocarcinoma (PAC). Magnetic resonance imaging (MRI) examination revealed another parotid lesion which was diagnosed as pleomorphic adenoma (PA). Palatal mass was resected with safety margin; superficial parotidectomy was also done for parotid lesion sparing facial nerve. Post-operative radiotherapy was recommended by pathologist due to evident perineural invasion of PAC. The patient is tumor free after one year follow-up. The present case has more than one risk factor which favors expectation of multiple tumors and mandate examination of all salivary tissues. In case of multiple salivary tumors each tumor should be diagnosed and treated separately according to its nature and extension. Keywords: Salivary gland; tumors; parotid; palate; MRI
{"title":"The advantage of MRI in detection of Coincidental adenocarcinoma of palate and pleomorphic adenoma of parotid - a case report","authors":"H. Sleem, I. Sharabasy, R. Foad","doi":"10.31491/csrc.2019.09.004","DOIUrl":"https://doi.org/10.31491/csrc.2019.09.004","url":null,"abstract":"Salivary gland tumors account for fewer than 3% of the head and neck tumors. Typically salivary gland neoplasm presented as a single swelling localized to one salivary gland. A more unusual event is the development of multiple neoplasms located either in different glands or in one gland. This manuscript present a case of palatal swelling diagnosed by incisional biopsy as polymorphous adenocarcinoma (PAC). Magnetic resonance imaging (MRI) examination revealed another parotid lesion which was diagnosed as pleomorphic adenoma (PA). Palatal mass was resected with safety margin; superficial parotidectomy was also done for parotid lesion sparing facial nerve. Post-operative radiotherapy was recommended by pathologist due to evident perineural invasion of PAC. The patient is tumor free after one year follow-up. The present case has more than one risk factor which favors expectation of multiple tumors and mandate examination of all salivary tissues. In case of multiple salivary tumors each tumor should be diagnosed and treated separately according to its nature and extension. Keywords: Salivary gland; tumors; parotid; palate; MRI","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114081615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective : Resveratrol exerts various biologic effects. This study was designed to investigate its anti-cancer effect and its impact on cell apoptosis, autophagy, and endoplasmic reticulum stress (ER-stress) in colon cancer. Methods : Colon cancer cells were treated with resveratrol. Cell viability, apoptosis, and autophagy were assessed by MTT, flow cytometry, and green fluorescence protein (GFP)-tagged LC3B analysis, respectively. Gene expression was detected by qRT-PCR and western blot. Xenograft model was subjected to verify the effects of resveratrol on tumorigenesis of colon cancer cells in vivo. Results : The viability of colon cancer cells was reduced by resveratrol. The cell apoptosis and the protein levels of apoptotic markers (cleaved-PARP and cleaved-Caspase3) were increased by resveratrol. The protein level of autophagic marker (MAP1LC3B) and the LC3B dots accumulation were elevated by resveratrol. Autophagy inhibitor (3-MA) partially reversed the effect of resveratrol on cell apoptosis. The protein and mRNA levels of ER-stress markers (IRE-1 and ATF6) and pro-apoptotic signals (GRP-78, GADD153) were up-regulated by resveratrol. The tumor growth of colon cancer cells was suppressed by resveratrol in vivo. Conclusion : Resveratrol exerts anti-cancer function of colon cancer, which is associated with its induction effect of cell apoptosis, autophagy and ER-stress. Keywords: resveratrol; colon cancer; apoptosis; autophagy; endoplasmic reticulum stress
{"title":"Resveratrol induces apoptosis, autophagy and endoplasmic reticulum stress in colon cancer cells","authors":"Hao-wei Jia, Yue Wu, Ruixin Li, Hongchao Zhao, Guojun Wang, Junfeng Sun","doi":"10.31491/csrc.2019.09.003","DOIUrl":"https://doi.org/10.31491/csrc.2019.09.003","url":null,"abstract":"Objective : Resveratrol exerts various biologic effects. This study was designed to investigate its anti-cancer effect and its impact on cell apoptosis, autophagy, and endoplasmic reticulum stress (ER-stress) in colon cancer. Methods : Colon cancer cells were treated with resveratrol. Cell viability, apoptosis, and autophagy were assessed by MTT, flow cytometry, and green fluorescence protein (GFP)-tagged LC3B analysis, respectively. Gene expression was detected by qRT-PCR and western blot. Xenograft model was subjected to verify the effects of resveratrol on tumorigenesis of colon cancer cells in vivo. Results : The viability of colon cancer cells was reduced by resveratrol. The cell apoptosis and the protein levels of apoptotic markers (cleaved-PARP and cleaved-Caspase3) were increased by resveratrol. The protein level of autophagic marker (MAP1LC3B) and the LC3B dots accumulation were elevated by resveratrol. Autophagy inhibitor (3-MA) partially reversed the effect of resveratrol on cell apoptosis. The protein and mRNA levels of ER-stress markers (IRE-1 and ATF6) and pro-apoptotic signals (GRP-78, GADD153) were up-regulated by resveratrol. The tumor growth of colon cancer cells was suppressed by resveratrol in vivo. Conclusion : Resveratrol exerts anti-cancer function of colon cancer, which is associated with its induction effect of cell apoptosis, autophagy and ER-stress. Keywords: resveratrol; colon cancer; apoptosis; autophagy; endoplasmic reticulum stress","PeriodicalId":158678,"journal":{"name":"Clinical Surgery Research Communications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130075570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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